Potential roles of gut microbiota and microbial metabolites in Parkinson’s disease

A human gut microbial gene catalogue established by metagenomic sequencing

MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624 · see citing works

Untitled work

Hill (2014) · doi:10.1038/nrgastro.2014.66 · Cited by 9,592 · see citing works

Diversity of the Human Intestinal Microbial Flora

Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913 · see citing works

Parkinson's disease

Kalia, L. V., & Lang, A. E. (2015) · The Lancet · doi:10.1016/s0140-6736(14)61393-3 · Cited by 6,412 · see citing works

The human microbiome project

Turnbaugh, P. J., Ley, R. E., Hamady, M., Fraser-Liggett, C. M., Knight, R., & Gordon, J. I. (2007) · Nature · doi:10.1038/nature06244 · Cited by 6,091 · see citing works

Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Feigin, V. L., Nichols, E., Alam, T., Bannick, M. S., Beghi, E., Blake, N., Culpepper, W. J., Dorsey, E. R., Elbaz, A., Ellenbogen, R. G., et al. (2019) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30499-x · Cited by 5,644 · see citing works

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

Gibson, G. R., Hutkins, R., Sanders, M. E., Prescott, S. L., Reimer, R. A., Salminen, S. J., Scott, K., Stanton, C., Swanson, K. S., Cani, P. D., et al. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.75 · Cited by 5,634 · see citing works

Parkinson disease

Poewe, W., Seppi, K., Tanner, C. M., Halliday, G. M., Brundin, P., Volkmann, J., Schrag, A.-E., & Lang, A. E. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.13 · Cited by 5,415 · see citing works

The Microbiota-Gut-Brain Axis

Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286 · see citing works

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

Cryan, J. F., & Dinan, T. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3346 · Cited by 4,572 · see citing works

Ingestion of <i>Lactobacillus</i> strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

Bravo, J. A., Forsythe, P., Chew, M. V., Escaravage, E., Savignac, H. M., Dinan, T. G., Bienenstock, J., & Cryan, J. F. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102999108 · Cited by 3,888 · see citing works

Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease

Sampson, T. R., Debelius, J. W., Thron, T., Janssen, S., Shastri, G. G., Ilhan, Z. E., Challis, C., Schretter, C. E., Rocha, S., Gradinaru, V., et al. (2016) · Cell · doi:10.1016/j.cell.2016.11.018 · Cited by 3,622 · see citing works

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis

Yano, J. M., Yu, K., Donaldson, G. P., Shastri, G. G., Ann, P., Ma, L., Nagler, C. R., Ismagilov, R. F., Mazmanian, S. K., & Hsiao, E. Y. (2015) · Cell · doi:10.1016/j.cell.2015.02.047 · Cited by 3,614 · see citing works

Host microbiota constantly control maturation and function of microglia in the CNS

Erny, D., Hrabě de Angelis, A. L., Jaitin, D., Wieghofer, P., Staszewski, O., David, E., Keren-Shaul, H., Mahlakoiv, T., Jakobshagen, K., Buch, T., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.4030 · Cited by 3,569 · see citing works

The role of short-chain fatty acids in microbiota–gut–brain communication

Dalile, B., Van Oudenhove, L., Vervliet, B., & Verbeke, K. (2019) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/s41575-019-0157-3 · Cited by 3,357 · see citing works

Short chain fatty acids in human large intestine, portal, hepatic and venous blood

Cummings, J. H., Pomare, E. W., Branch, W. J., Naylor, C. P., & Macfarlane, G. T. (1987) · Gut · doi:10.1136/gut.28.10.1221 · Cited by 3,119 · see citing works

Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides

Topping, D. L., & Clifton, P. M. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1031 · Cited by 3,091 · see citing works

Diagnosis and Treatment of Parkinson Disease: A Review

Armstrong, M. J., & Okun, M. S. (2020) · JAMA · doi:10.1001/jama.2019.22360 · Cited by 2,924 · see citing works

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Dorsey, E. R., Elbaz, A., Nichols, E., Abbasi, N., Abd-Allah, F., Abdelalim, A., Adsuar, J. C., Ansha, M. G., Brayne, C., Choi, J.-Y. J., et al. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30295-3 · Cited by 2,816 · see citing works

Current understanding of the human microbiome

Gilbert, J. A., Blaser, M. J., Caporaso, J. G., Jansson, J. K., Lynch, S. V., & Knight, R. (2018) · Nature Medicine · doi:10.1038/nm.4517 · Cited by 2,609 · see citing works

The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems.

(2015) · PubMed Central · Cited by 2,540 · see citing works

The gut microbiota influences blood-brain barrier permeability in mice

Braniste, V., Al-Asmakh, M., Kowal, C., Anuar, F., Abbaspour, A., Tóth, M., Korecka, A., Bakocevic, N., Ng, L. G., Kundu, P., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009759 · Cited by 2,530 · see citing works

Effects of probiotics, prebiotics, and synbiotics on human health

Markowiak, P., & Śliżewska, K. (2017) · Nutrients · doi:10.3390/nu9091021 · Cited by 2,401 · see citing works

Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

Feigin, V. L., Abajobir, A. A., Abate, K. H., Abd-Allah, F., Abdulle, A. M., Abera, S. F., Abyu, G. Y., Ahmed, M. B., Aichour, A. N., Aichour, I., et al. (2017) · The Lancet Neurology · doi:10.1016/s1474-4422(17)30299-5 · Cited by 2,275 · see citing works

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

Lavelle, A., & Sokol, H. (2020) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/s41575-019-0258-z · Cited by 2,015 · see citing works

The Emerging Evidence of the Parkinson Pandemic

Dorsey, E. R., Sherer, T., Okun, M. S., & Bloem, B. R. (2018) · Journal of Parkinson s Disease · doi:10.3233/jpd-181474 · Cited by 1,995 · see citing works

Gut microbiota are related to Parkinson's disease and clinical phenotype

Scheperjans, F., Aho, V., Pereira, P. A. B., Koskinen, K., Paulin, L., Pekkonen, E., Haapaniemi, E., Kaakkola, S., Eerola‐Rautio, J., Pohja, M., et al. (2015) · Movement Disorders · doi:10.1002/mds.26069 · Cited by 1,968 · see citing works

Extensive impact of non-antibiotic drugs on human gut bacteria

Maier, L., Pruteanu, M., Kuhn, M., Zeller, G., Telzerow, A., Anderson, E. E., Brochado, A. R., Fernandez, K. C., Dose, H., Mori, H., et al. (2018) · Nature · doi:10.1038/nature25979 · Cited by 1,905 · see citing works

The interplay between the intestinal microbiota and the brain

Collins, S. M., Surette, M., & Bercik, P. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2876 · Cited by 1,611 · see citing works

Parkinson disease

Balestrino, R., & Schapira, A. H. V. (2020) · European Journal of Neurology · doi:10.1111/ene.14108 · Cited by 1,508 · see citing works

Microbiota Transfer Therapy Alters Gut Ecosystem and Improves Gastrointestinal and Autism Symptoms: An Open-Label Study

Kang, D.-W., Adams, J. B., Gregory, A. C., Borody, T., Chittick, L., Fasano, A., Khoruts, A., Geis, E., Maldonado, J., McDonough-Means, S., et al. (2017) · Microbiome · doi:10.1186/s40168-016-0225-7 · Cited by 1,391 · see citing works

Gastric α-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology

Braak, H., de Vos, R. A. I., Bohl, J., & Del Tredici, K. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2005.11.012 · Cited by 1,354 · see citing works

The gut microbiome in neurological disorders

Cryan, J. F., O'Riordan, K. J., Sandhu, K., Peterson, V., & Dinan, T. G. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(19)30356-4 · Cited by 1,336 · see citing works

How informative is the mouse for human gut microbiota research?

Nguyen, T. L. A., Vieira-Silva, S., Liston, A., & Raes, J. (2015) · Disease Models &amp; Mechanisms · doi:10.1242/dmm.017400 · Cited by 1,334 · see citing works

Colonic bacterial composition in Parkinson's disease

Keshavarzian, A., Green, S. J., Engen, P. A., Voigt, R. M., Naqib, A., Forsyth, C. B., Mutlu, E., & Shannon, K. M. (2015) · Movement Disorders · doi:10.1002/mds.26307 · Cited by 1,281 · see citing works

Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

Unger, M. M., Spiegel, J., Dillmann, K.-U., Grundmann, D., Philippeit, H., Bürmann, J., Faßbender, K., Schwiertz, A., & Schäfer, K.-H. (2016) · Parkinsonism &amp; Related Disorders · doi:10.1016/j.parkreldis.2016.08.019 · Cited by 1,159 · see citing works

The Human Gut Microbiome – A Potential Controller of Wellness and Disease

Kho, Z. Y., & Lal, S. K. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01835 · Cited by 1,116 · see citing works

Control of brain development, function, and behavior by the microbiome

Sampson, T. R., & Mazmanian, S. K. (2015) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2015.04.011 · Cited by 1,093 · see citing works

Short- and medium-chain fatty acids in energy metabolism: the cellular perspective

Schönfeld, P., & Wojtczak, L. (2016) · Journal of Lipid Research · doi:10.1194/jlr.r067629 · Cited by 1,088 · see citing works

Short chain fatty acids in the human colon.

Cummings, J. H. (1981) · Gut · doi:10.1136/gut.22.9.763 · Cited by 1,050 · see citing works

The SH-SY5Y cell line in Parkinson’s disease research: a systematic review

Xicoy, H., Wieringa, B., & Martens, G. J. M. (2017) · Molecular Neurodegeneration · doi:10.1186/s13024-017-0149-0 · Cited by 1,036 · see citing works

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

Bercik, P., Park, A. J., Sinclair, D., Khoshdel, A., Lu, J., Huang, X., Deng, Y., Blennerhassett, P. A., Fahnestock, M., Moine, D., et al. (2011) · Neurogastroenterology &amp; Motility · doi:10.1111/j.1365-2982.2011.01796.x · Cited by 1,018 · see citing works

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

Forsyth, C. B., Shannon, K. M., Kordower, J. H., Voigt, R. M., Shaikh, M., Jaglin, J. A., Estes, J. D., Dodiya, H. B., & Keshavarzian, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028032 · Cited by 974 · see citing works

Ectopic colonization of oral bacteria in the intestine drives T _H 1 cell induction and inflammation

Atarashi, K., Suda, W., Luo, C., Kawaguchi, T., Motoo, I., Narushima, S., Kiguchi, Y., Yasuma, K., Watanabe, E., Tanoue, T., et al. (2017) · Science · doi:10.1126/science.aan4526 · Cited by 957 · see citing works

Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice

Burokas, A., Arboleya, S., Moloney, R. D., Peterson, V. L., Murphy, K., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.12.031 · Cited by 952 · see citing works

Risk and safety of probiotics

Doron, S., & Snydman, D. R. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ085 · Cited by 942 · see citing works

Interaction between the gut microbiome and mucosal immune system

Shi, N., Li, N., Duan, X., & Niu, H. (2017) · Military Medical Research · doi:10.1186/s40779-017-0122-9 · Cited by 940 · see citing works

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

Holmqvist, S., Chutna, O., Bousset, L., Aldrin-Kirk, P., Li, W., Björklund, T., Wang, Z.-Y., Roybon, L., Melki, R., & Li, J.-Y. (2014) · Acta Neuropathologica · doi:10.1007/s00401-014-1343-6 · Cited by 925 · see citing works

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome

Hill‐Burns, E. M., Debelius, J. W., Morton, J. T., Wissemann, W. T., Lewis, M. R., Wallen, Z. D., Peddada, S. D., Factor, S. A., Molho, E., Zabetian, C. P., et al. (2017) · Movement Disorders · doi:10.1002/mds.26942 · Cited by 874 · see citing works

Vagotomy and subsequent risk of <scp>P</scp> arkinson's disease

Svensson, E., Horváth‐Puhó, E., Thomsen, R. W., Djurhuus, J. C., Pedersen, L., Borghammer, P., & Sørensen, H. T. (2015) · Annals of Neurology · doi:10.1002/ana.24448 · Cited by 806 · see citing works

GPR109A Is a G-protein–Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

Thangaraju, M., Cresci, G. A., Liu, K., Ananth, S., Gnanaprakasam, J. P., Browning, D. D., Mellinger, J. D., Smith, S. B., Digby, G. J., Lambert, N. A., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-4466 · Cited by 789 · see citing works

Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain–gut axis alterations

van de Wouw, M., Boehme, M., Lyte, J. M., Wiley, N., Strain, C., O'Sullivan, O., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F. (2018) · The Journal of Physiology · doi:10.1113/jp276431 · Cited by 789 · see citing works

Acetate Utilization and Butyryl Coenzyme A (CoA):Acetate-CoA Transferase in Butyrate-Producing Bacteria from the Human Large Intestine

Duncan, S. H., Barcenilla, A., Stewart, C. S., Pryde, S. E., & Flint, H. J. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.10.5186-5190.2002 · Cited by 743 · see citing works

Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson's disease mice: gut microbiota, glial reaction and TLR4/TNF-α signaling pathway

Sun, M.-F., Zhu, Y.-L., Zhou, Z.-L., Jia, X.-B., Xu, Y.-D., Yang, Q., Cui, C., & Shen, Y.-Q. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.02.005 · Cited by 736 · see citing works

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

Calvert, J. W., Jha, S. K., Gundewar, S., Elrod, J. W., Ramachandran, A., Pattillo, C. B., Kevil, C. G., & Lefer, D. J. (2009) · Circulation Research · doi:10.1161/circresaha.109.199919 · Cited by 722 · see citing works

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

Asano, Y., Hiramoto, T., Nishino, R., Aiba, Y., Kimura, T., Yoshihara, K., Koga, Y., & Sudo, N. (2012) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00341.2012 · Cited by 659 · see citing works

Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naive Parkinson's disease patients

Bedarf, J. R., Hildebrand, F., Coelho, L. P., Sunagawa, S., Bahram, M., Goeser, F., Bork, P., & Wüllner, U. (2017) · Genome Medicine · doi:10.1186/s13073-017-0428-y · Cited by 642 · see citing works

Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism

Duscha, A., Gisevius, B., Hirschberg, S., Yissachar, N., Stangl, G. I., Dawin, E., Bader, V., Haase, S., Kaisler, J., David, C., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.035 · Cited by 639 · see citing works

Systematic review with meta‐analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory <i>Clostridium difficile</i> infection

Quraishi, M. N., Widlak, M., Bhala, N., Moore, D., Price, M., Sharma, N., & Iqbal, T. H. (2017) · Alimentary Pharmacology &amp; Therapeutics · doi:10.1111/apt.14201 · Cited by 617 · see citing works

BDNF function and intracellular signaling in neurons.

Numakawa, T., Suzuki, S., Kumamaru, E., Adachi, N., Richards, M., & Kunugi, H. (2010) · PubMed · doi:10.14670/hh-25.237 · Cited by 598 · see citing works

The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?

Houser, M. C., & Tansey, M. G. (2017) · npj Parkinson's Disease · doi:10.1038/s41531-016-0002-0 · Cited by 588 · see citing works

Brain-Gut-Microbiota Axis in Parkinson’s Disease

Mulak, A. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i37.10609 · Cited by 583 · see citing works

Sodium Butyrate Inhibits Inflammation and Maintains Epithelium Barrier Integrity in a TNBS-induced Inflammatory Bowel Disease Mice Model

Chen, G., Ran, X., Li, B., Li, Y., He, D., Huang, B., Fu, S., Liu, J., & Wang, W. (2018) · eBioMedicine · doi:10.1016/j.ebiom.2018.03.030 · Cited by 580 · see citing works

Fecal microbiota transplantation: Review and update

Wang, J.-W., Kuo, C.-H., Kuo, F.-C., Wang, Y.-K., Hsu, W.-H., Yu, F.-J., Hu, H.-M., Hsu, P.-I., Wang, J.-Y., & Wu, D.-C. (2019) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2018.08.011 · Cited by 576 · see citing works

The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder

Heintz‐Buschart, A., Pandey, U., Wicke, T., Sixel‐Döring, F., Janzen, A., Sittig‐Wiegand, E., Trenkwalder, C., Oertel, W. H., Mollenhauer, B., & Wilmes, P. (2018) · Movement Disorders · doi:10.1002/mds.27105 · Cited by 554 · see citing works

The gut microbiome in human neurological disease: A review

Tremlett, H., Bauer, K. C., Appel‐Cresswell, S., Finlay, B. B., & Waubant, E. (2017) · Annals of Neurology · doi:10.1002/ana.24901 · Cited by 535 · see citing works

The blood-brain barrier and immune function and dysfunction

Banks, W. A., & Erickson, M. A. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.07.031 · Cited by 523 · see citing works

Intestinal dysbiosis and lowered serum lipopolysaccharide-binding protein in Parkinson's disease

Hasegawa, S., Goto, S., Tsuji, H., Okuno, T., Asahara, T., Nomoto, K., Shibata, A., Fujisawa, Y., Minato, T., Okamoto, A., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0142164 · Cited by 523 · see citing works

Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease

van Kessel, S. P., Frye, A. K., El-Gendy, A. O., Castejon, M., Keshavarzian, A., van Dijk, G., & El Aidy, S. (2019) · Nature Communications · doi:10.1038/s41467-019-08294-y · Cited by 521 · see citing works

Regulation of intestinal lipid metabolism: current concepts and relevance to disease

Ko, C.-W., Qu, J., Black, D. D., & Tso, P. (2020) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/s41575-019-0250-7 · Cited by 510 · see citing works

Effect of probiotics on depression: a systematic review and meta-analysis of randomized controlled trials

Huang, R., Wang, K., & Hu, J. (2016) · Nutrients · doi:10.3390/nu8080483 · Cited by 505 · see citing works

Parkinson’s Disease

Reich, S. G., & Savitt, J. M. (2018) · Medical Clinics of North America · doi:10.1016/j.mcna.2018.10.014 · Cited by 501 · see citing works

Probiotics as modulators of the gut flora

Fooks, L. J., & Gibson, G. R. (2002) · British Journal Of Nutrition · doi:10.1079/bjn2002628 · Cited by 499 · see citing works

Feeding the microbiota–gut–brain axis: Diet, microbiome, and neuropsychiatry

Sandhu, K. V., Sherwin, E., Schellekens, H., Stanton, C., Dinan, T. G., & Cryan, J. F. (2017) · Translational Research · doi:10.1016/j.trsl.2016.10.002 · Cited by 491 · see citing works

Host–microbiota interactions in immune-mediated diseases

Ruff, W. E., Greiling, T. M., & Kriegel, M. A. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0367-2 · Cited by 489 · see citing works

Analysis of Gut Microbiota in Patients with Parkinson’s Disease

Petrov, V. A., Saltykova, I. V., Zhukova, I. A., Alifirova, V. M., Zhukova, N. G., Dorofeeva, Y. B., Tyakht, A. V., Kovarsky, B. A., Alekseev, D. G., Kostryukova, E. S., et al. (2017) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-017-3700-7 · Cited by 487 · see citing works

Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson's disease

Lin, C.-H., Chen, C.-C., Chiang, H.-L., Liou, J.-M., Chang, C.-M., Lu, T.-P., Chuang, E. Y., Tai, Y.-C., Cheng, C., Lin, H.-Y., et al. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1528-y · Cited by 469 · see citing works

Role of TLR4 in the gut-brain axis in Parkinson's disease: A translational study from men to mice

Perez-Pardo, P., Dodiya, H. B., Engen, P. A., Forsyth, C. B., Huschens, A. M., Shaikh, M., Voigt, R. M., Naqib, A., Green, S. J., Kordower, J. H., et al. (2019) · Gut · doi:10.1136/gutjnl-2018-316844 · Cited by 467 · see citing works

Vagotomy and Parkinson disease: A Swedish register–based matched-cohort study

Liu, B., Fang, F., Pedersen, N. L., Tillander, A., Ludvigsson, J. F., Ekbom, A., Svenningsson, P., Chen, H., & Wirdefeldt, K. (2017) · Neurology · doi:10.1212/wnl.0000000000003961 · Cited by 447 · see citing works

Dysbiosis of gut microbiota and microbial metabolites in Parkinson's disease

Sun, M.-F., & Shen, Y.-Q. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.04.004 · Cited by 445 · see citing works

Collaborative JPEN‐Clinical Nutrition Scientific Publications Role of intestinal bacteria in nutrient metabolism

Cummings, J. H., & Macfarlane, G. T. (1997) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607197021006357 · Cited by 437 · see citing works

Faecal microbiota transplantation versus placebo for moderate-to-severe irritable bowel syndrome: a double-blind, randomised, placebo-controlled, parallel-group, single-centre trial

Johnsen, P. H., Hilpüsch, F., Cavanagh, J. P., Leikanger, I. S., Kolstad, C., Valle, P. C., & Goll, R. (2018) · The Lancet Gastroenterology &amp; Hepatology · doi:10.1016/s2468-1253(17)30338-2 · Cited by 437 · see citing works

Medical records documentation of constipation preceding Parkinson disease

Savica, R., Carlin, J. M., Grossardt, B. R., Bower, J. H., Ahlskog, J. E., Maraganore, D. M., Bharucha, A. E., & Rocca, W. A. (2009) · Neurology · doi:10.1212/wnl.0b013e3181c34af5 · Cited by 431 · see citing works

Pathological α‐synuclein in gastrointestinal tissues from prodromal <scp>P</scp> arkinson disease patients

Stokholm, M. G., Danielsen, E. H., Hamilton‐Dutoit, S. J., & Borghammer, P. (2016) · Annals of Neurology · doi:10.1002/ana.24648 · Cited by 415 · see citing works

Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease

Qian, Y., Yang, X., Xu, S., Wu, C., Song, Y., Qin, N., Chen, S.-D., & Xiao, Q. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.02.016 · Cited by 409 · see citing works

Structural changes of gut microbiota in Parkinson's disease and its correlation with clinical features

Li, W., Wu, X., Hu, X., Wang, T., Liang, S., Duan, Y., Jin, F., & Qin, B. (2017) · Science China Life Sciences · doi:10.1007/s11427-016-9001-4 · Cited by 406 · see citing works

Probiotics, prebiotics, and synbiotics: impact on the gut immune system and allergic reactions

Gourbeyre, P., Denery-Papini, S., & Bodinier, M. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.1109753 · Cited by 396 · see citing works

Exploring Braak’s hypothesis of Parkinson’s disease

Rietdijk, C. D., Perez-Pardo, P., Garssen, J., van Wezel, R. J. A., & Kraneveld, A. D. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00037 · Cited by 395 · see citing works

Unraveling gut microbiota in Parkinson's disease and atypical parkinsonism

Barichella, M., Severgnini, M., Cilia, R., Cassani, E., Bolliri, C., Caronni, S., Ferri, V., Cancello, R., Ceccarani, C., Faierman, S., et al. (2019) · Movement Disorders · doi:10.1002/mds.27581 · Cited by 393 · see citing works

Probiotics and prebiotic fiber for constipation associated with Parkinson disease: An RCT

Barichella, M., Pacchetti, C., Bolliri, C., Cassani, E., Iorio, L., Pusani, C., Pinelli, G., Privitera, G., Cesari, I., Faierman, S. A., et al. (2016) · Neurology · doi:10.1212/wnl.0000000000003127 · Cited by 390 · see citing works

Intestinal Microbiota Distinguish Gout Patients from Healthy Humans

Guo, Z., Zhang, J., Wang, Z., Ang, K. Y., Huang, S. W., Hou, Q., Su, X., Qiao, J., Zheng, Y., Wang, L., et al. (2016) · Scientific Reports · doi:10.1038/srep20602 · Cited by 381 · see citing works

Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine

Savignac, H. M., Corona, G., Mills, H., Chen, L., Spencer, J. P. E., Tzortzis, G., & Burnet, P. W. J. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.10.006 · Cited by 377 · see citing works

The Gut Microbiota and Unhealthy Aging: Disentangling Cause from Consequence

DeJong, E. N., Surette, M. G., & Bowdish, D. M. E. (2020) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2020.07.013 · Cited by 370 · see citing works

Neuroprotective effects of hydrogen sulfide on Parkinson’s disease rat models

Hu, L., Lu, M., Tiong, C. X., Dawe, G. S., Hu, G., & Bian, J. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2009.00543.x · Cited by 365 · see citing works

A Typical Immune T/B Subset Profile Characterizes Bicuspid Aortic Valve: In an Old Status?

Balistreri, C. R., Buffa, S., Allegra, A., Pisano, C., Ruvolo, G., Colonna‐Romano, G., Lio, D., Mazzesi, G., Schiavon, S., Greco, E., et al. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/5879281 · Cited by 365 · see citing works

Brain–gut–microbiota axis — mood, metabolism and behaviour

Dinan, T. G., & Cryan, J. F. (2017) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/nrgastro.2016.200 · Cited by 361 · see citing works

Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression

Aho, V. T. E., Pereira, P. A. B., Voutilainen, S., Paulin, L., Pekkonen, E., Auvinen, P., & Scheperjans, F. (2019) · eBioMedicine · doi:10.1016/j.ebiom.2019.05.064 · Cited by 361 · see citing works

Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects

Kelly, J. R., Allen, A. P., Temko, A., Hutch, W., Kennedy, P. J., Farid, N., Murphy, E., Boylan, G., Bienenstock, J., Cryan, J. F., et al. (2017) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2016.11.018 · Cited by 355 · see citing works

Towards microbial fermentation metabolites as markers for health benefits of prebiotics

Verbeke, K. A., Boobis, A. R., Chiodini, A., Edwards, C. A., Franck, A., Kleerebezem, M., Nauta, A., Raes, J., van Tol, E. A. F., & Tuohy, K. M. (2015) · Nutrition Research Reviews · doi:10.1017/s0954422415000037 · Cited by 343 · see citing works

Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study

Halkjær, S. I., Christensen, A. H., Lo, B. Z. S., Browne, P. D., Günther, S., Hansen, L. H., & Petersen, A. M. (2018) · Gut · doi:10.1136/gutjnl-2018-316434 · Cited by 340 · see citing works

Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson’s Disease

Caputi, V., & Giron, M. C. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19061689 · Cited by 338 · see citing works

Reduction of butyrate- and methane-producing microorganisms in patients with Irritable Bowel Syndrome

Pozuelo, M., Panda, S., Santiago, A., Mendez, S., Accarino, A. M., Santos, J., Guarner, F., Azpiroz, F., & Manichanh, C. (2015) · Scientific Reports · doi:10.1038/srep12693 · Cited by 325 · see citing works

Gut microbiota in Parkinson disease in a northern German cohort

Hopfner, F., Künstner, A., Müller, S. H., Künzel, S., Zeuner, K. E., Margraf, N. G., Deuschl, G., Baines, J. F., & Kuhlenbäumer, G. (2017) · Brain Research · doi:10.1016/j.brainres.2017.04.019 · Cited by 318 · see citing works

Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease

Kelly, L. P., Carvey, P. M., Keshavarzian, A., Shannon, K. M., Shaikh, M., Bakay, R. A. E., & Kordower, J. H. (2014) · Movement Disorders · doi:10.1002/mds.25736 · Cited by 308 · see citing works

Modulation of Gut Microbiota–Brain Axis by Probiotics, Prebiotics, and Diet

Liu, X., Cao, S., & Zhang, X. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b02404 · Cited by 304 · see citing works

Changes of colonic bacterial composition in Parkinson's disease and other neurodegenerative diseases

Gerhardt, S., & Mohajeri, M. H. (2018) · Nutrients · doi:10.3390/nu10060708 · Cited by 298 · see citing works

Structural alterations of the intestinal epithelial barrier in Parkinson’s disease

Clairembault, T., Leclair‐Visonneau, L., Coron, E., Bourreille, A., Dily, S. L., Vavasseur, F., Heymann, M., Neunlist, M., & Derkinderen, P. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0196-0 · Cited by 292 · see citing works

Gut Microbiota and Metabolome Alterations Associated with Parkinson’s Disease

Vascellari, S., Palmas, V., Melis, M., Pisanu, S., Cusano, R., Uva, P., Perra, D., Madau, V., Sarchioto, M., Oppo, V., et al. (2020) · mSystems · doi:10.1128/msystems.00561-20 · Cited by 291 · see citing works

Probiotic Clostridium butyricum ameliorated motor deficits in a mouse model of Parkinson’s disease via gut microbiota-GLP-1 pathway

Sun, J., Li, H., Jin, Y., Yu, J., Mao, S., Su, K.-P., Ling, Z., & Liu, J. (2021) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.10.014 · Cited by 264 · see citing works

Gut microbiota in patients with Parkinson's disease in southern China

Lin, A., Zheng, W., He, Y., Tang, W., Wei, X., He, R., Huang, W., Su, Y., Huang, Y., Zhou, H., et al. (2018) · Parkinsonism &amp; Related Disorders · doi:10.1016/j.parkreldis.2018.05.007 · Cited by 253 · see citing works

Characterizing Dysbiosis of Gut Microbiome in PD: Evidence for Overabundance of Opportunistic Pathogens

Wallen, Z. D., Appah, M., Dean, M. N., Sesler, C. L., Factor, S. A., Molho, E., Zabetian, C. P., Standaert, D. G., & Payami, H. (2020) · npj Parkinson s Disease · doi:10.1038/s41531-020-0112-6 · Cited by 252 · see citing works

Progression of Parkinson's disease is associated with gut dysbiosis: Two-year follow-up study

Minato, T., Maeda, T., Fujisawa, Y., Tsuji, H., Nomoto, K., Ohno, K., & Hirayama, M. (2017) · PLOS ONE · doi:10.1371/journal.pone.0187307 · Cited by 248 · see citing works

Fecal microbiota transplantation broadening its application beyond intestinal disorders

Xu, M.-Q. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i1.102 · Cited by 231 · see citing works

Epigenetic targeting of histone deacetylase: Therapeutic potential in Parkinson's disease?

Harrison, I. F., & Dexter, D. T. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.05.010 · Cited by 227 · see citing works

Probiotics for Constipation in Parkinson Disease: A Randomized Placebo-Controlled Study

Tan, A. H., Lim, S.-Y., Chong, K. K., A Manap, M. A. A., Hor, J. W., Lim, J. L., Low, S. C., Chong, C. W., Mahadeva, S., & Lang, A. E. (2021) · Neurology · doi:10.1212/wnl.0000000000010998 · Cited by 226 · see citing works

Virtual reality in research and rehabilitation of gait and balance in Parkinson disease

Canning, C. G., Allen, N. E., Nackaerts, E., Paul, S. S., Nieuwboer, A., & Gilat, M. (2020) · Nature Reviews Neurology · doi:10.1038/s41582-020-0370-2 · Cited by 225 · see citing works

Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1

Liu, J., Wang, F., Liu, S., Du, J., Hu, X., Xiong, J., Fang, R., Chen, W., & Sun, J. (2017) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2017.08.3235 · Cited by 218 · see citing works

Dysbiosis of gut microbiota in a selected population of Parkinson's patients

Pietrucci, D., Cerroni, R., Unida, V., Farcomeni, A., Pierantozzi, M., Mercuri, N. B., Biocca, S., Stefani, A., & Desideri, A. (2019) · Parkinsonism &amp; Related Disorders · doi:10.1016/j.parkreldis.2019.06.003 · Cited by 217 · see citing works

Oxidative Stress and the Microbiota‐Gut‐Brain Axis

Dumitrescu, L., Mitrea, I., Cozma, L., Tulbă, D., Hinescu, M. E., Ceafalan, L. C., Gherghiceanu, M., & Popescu, B. O. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/2406594 · Cited by 214 · see citing works

Meta-analyses on prevalence of selected Parkinson's nonmotor symptoms before and after diagnosis

Chen, H., Zhao, E. J., Zhang, W., Lu, Y., Liu, R., Huang, X., Ciesielski-Jones, A. J., Justice, M. A., Cousins, D. S., & Peddada, S. (2015) · Translational Neurodegeneration · doi:10.1186/2047-9158-4-1 · Cited by 212 · see citing works

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

Srivastav, S., Neupane, S., Bhurtel, S., Katila, N., Maharjan, S., Choi, H., Hong, J. T., & Choi, D.-Y. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.03.021 · Cited by 212 · see citing works

Hydrogen Sulfide: A Neuromodulator and Neuroprotectant in the Central Nervous System

Zhang, X., & Bian, J. (2014) · ACS Chemical Neuroscience · doi:10.1021/cn500185g · Cited by 210 · see citing works

Untitled work

(2011) · PubMed · Cited by 207 · see citing works

Oral and nasal microbiota in Parkinson's disease

Pereira, P. A. B., Aho, V. T. E., Paulin, L. G., Pekkonen, E., Auvinen, P., & Scheperjans, F. (2017) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2017.02.026 · Cited by 207 · see citing works

Lactobacillus plantarum DR7 alleviates stress and anxiety in adults: a randomised, double-blind, placebo-controlled study

Chong, H.-X., Yusoff, N., Hor, Y.-Y., Lew, L.-C., Jaafar, M. H., Choi, S. B., Yusoff, M. S. B., Wahid, N. A., Abdullah, M. F. I. L. B., Zakaria, N., et al. (2019) · Beneficial Microbes · doi:10.3920/bm2018.0135 · Cited by 207 · see citing works

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease

Fujita, K., Seike, T., Yutsudo, N., Ohno, M., Yamada, H., Yamaguchi, H., Sakumi, K., Yamakawa, Y., Kido, M. A., Takaki, A., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007247 · Cited by 203 · see citing works

The Gut-Brain Axis in Parkinson’s Disease: Possibilities for Food-Based Therapies

Perez-Pardo, P., Kliest, T., Dodiya, H. B., Broersen, L. M., Garssen, J., Keshavarzian, A., & Kraneveld, A. D. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.05.042 · Cited by 203 · see citing works

Efficacy of different faecal microbiota transplantation protocols for <i>Clostridium difficile</i> infection: A systematic review and meta‐analysis

Ianiro, G., Maida, M., Burisch, J., Simonelli, C., Hold, G., Ventimiglia, M., Gasbarrini, A., & Cammarota, G. (2018) · United European Gastroenterology Journal · doi:10.1177/2050640618780762 · Cited by 203 · see citing works

Fecal microbiota transplantation to treat Parkinson's disease with constipation: A case report

Huang, H., Xu, H., Luo, Q., He, J., Li, M., Chen, H., Tang, W., Nie, Y., & Zhou, Y. (2019) · Medicine · doi:10.1097/md.0000000000016163 · Cited by 201 · see citing works

Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease

St. Laurent, R., O’Brien, L. M., & Ahmad, S. T. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.04.037 · Cited by 199 · see citing works

Gut Microbial Ecosystem in Parkinson Disease: New Clinicobiological Insights from Multi‐Omics

Tan, A. H., Chong, C. W., Lim, S., Yap, I. K. S., Teh, C. S. J., Loke, M. F., Song, S., Tan, J. Y., Ang, B. H., Tan, Y. Q., et al. (2021) · Annals of Neurology · doi:10.1002/ana.25982 · Cited by 196 · see citing works

Neuroprotection of fasting mimicking diet on MPTP-induced Parkinson's disease mice via gut microbiota and metabolites

Zhou, Z.-L., Jia, X.-B., Sun, M.-F., Zhu, Y.-L., Qiao, C.-M., Zhang, B.-P., Zhao, L.-P., Yang, Q., Cui, C., Chen, X., et al. (2019) · Neurotherapeutics · doi:10.1007/s13311-019-00719-2 · Cited by 195 · see citing works

Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinson’s disease

Kida, K., Yamada, M., Tokuda, K., Marutani, E., Kakinohana, M., Kaneki, M., & Ichinose, F. (2011) · Antioxidants &amp; Redox Signaling · doi:10.1089/ars.2010.3671 · Cited by 191 · see citing works

Fecal microbiota transplantation therapy for Parkinson's disease: A preliminary study

Xue, L.-J., Yang, X.-Z., Tong, Q., Shen, P., Ma, S.-J., Wu, S.-N., Zheng, J.-L., & Wang, H.-G. (2020) · Medicine · doi:10.1097/md.0000000000022035 · Cited by 186 · see citing works

Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

Paiva, I., Pinho, R., Pavlou, M. A., Hennion, M., Wales, P., Schütz, A.-L., Rajput, A., Szegő, É. M., Kerimoglu, C., Gerhardt, E., et al. (2017) · Human Molecular Genetics · doi:10.1093/hmg/ddx114 · Cited by 185 · see citing works

Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections

Ulusoy, A., Phillips, R. J., Helwig, M., Klinkenberg, M., Powley, T. L., & Di Monte, D. A. (2017) · Acta Neuropathologica · doi:10.1007/s00401-016-1661-y · Cited by 179 · see citing works

Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease

Zhou, W., Bercury, K. K., Cummiskey, J., Luong, N., Lebin, J. A., & Freed, C. R. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.211029 · Cited by 178 · see citing works

Exploiting gut bacteriophages for human health

Dalmasso, M., Hill, C., & Ross, R. P. (2014) · Trends in Microbiology · doi:10.1016/j.tim.2014.02.010 · Cited by 177 · see citing works

Probiotics Alleviate the progressive deterioration of motor functions in a mouse model of Parkinson’s disease

Hsieh, T.-H., Kuo, C.-W., Hsieh, K.-H., Shieh, M.-J., Peng, C.-W., Chen, Y.-C., Chang, Y.-L., Huang, Y.-Z., Chen, C.-C., Chang, P.-K., et al. (2020) · Brain Sciences · doi:10.3390/brainsci10040206 · Cited by 174 · see citing works

Gut Microbiota Altered in Mild Cognitive Impairment Compared With Normal Cognition in Sporadic Parkinson's Disease

Ren, T., Gao, Y., Qiu, Y., Jiang, S., Zhang, Q., Zhang, J., Wang, L., Zhang, Y., Wang, L., & Nie, K. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00137 · Cited by 173 · see citing works

Oral administration of Proteus mirabilis damages dopaminergic neurons and motor functions in mice

Choi, J. G., Kim, N., Ju, I. G., Eo, H., Lim, S.-M., Jang, S.-E., Kim, D.-H., & Oh, M. S. (2018) · Scientific Reports · doi:10.1038/s41598-018-19646-x · Cited by 170 · see citing works

Intestinal pathology and gut microbiota alterations in a methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

Lai, F., Jiang, R., Xie, W., Liu, X., Tang, Y., Xiao, H., Gao, J., Jia, Y., & Bai, Q. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2620-x · Cited by 169 · see citing works

Psychotropics and the Microbiome: a Chamber of Secrets…

Cussotto, S., Clarke, G. A., Dinan, T. G., & Cryan, J. F. (2019) · Psychopharmacology · doi:10.1007/s00213-019-5185-8 · Cited by 169 · see citing works

Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systematic Review

Boertien, J. M., Pereira, P. A. B., Aho, V. T. E., & Scheperjans, F. (2019) · Journal of Parkinson s Disease · doi:10.3233/jpd-191711 · Cited by 169 · see citing works

Hydrogen cross-feeders of the human gastrointestinal tract

Smith, N. W., Shorten, P. R., Altermann, E., Roy, N. C., & McNabb, W. C. (2018) · Gut Microbes · doi:10.1080/19490976.2018.1546522 · Cited by 165 · see citing works

Probiotic-based strategies for therapeutic and prophylactic use against multiple gastrointestinal diseases

Varankovich, N. V., Nickerson, M. T., & Korber, D. R. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00685 · Cited by 164 · see citing works

Network imaging biomarkers: insights and clinical applications in Parkinson's disease

Schindlbeck, K. A., & Eidelberg, D. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30169-8 · Cited by 163 · see citing works

Starke Belege: Parkinson könnte im Verdauungstrakt beginnen

(2017) · Fortschritte der Neurologie · Psychiatrie · doi:10.1055/s-0043-113319 · Cited by 162 · see citing works

Involvement of the kynurenine pathway in the pathogenesis of Parkinson's disease

Lim, C. K., Fernández-Gomez, F. J., Braidy, N., Estrada, C., Costa, C., Costa, S., Bessede, A., Fernandez-Villalba, E., Zinger, A., Herrero, M. T., et al. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.12.009 · Cited by 159 · see citing works

Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant

Hoenen, C., Gustin, A., Birck, C., Kirchmeyer, M., Beaume, N., Felten, P., Grandbarbe, L., Heuschling, P., & Heurtaux, T. (2016) · PLOS ONE · doi:10.1371/journal.pone.0162717 · Cited by 159 · see citing works

Sensitivity and Specificity of Diagnostic Criteria for Progressive Supranuclear Palsy

Ali, F., Martin, P. R., Botha, H., Ahlskog, J. E., Bower, J. H., Masumoto, J. Y., Maraganore, D. M., Hassan, A., Eggers, S. D. Z., Boeve, B. F., et al. (2019) · Movement Disorders · doi:10.1002/mds.27619 · Cited by 157 · see citing works

A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys

Ottosson, D. R., Iderberg, H., Li, Q., Dekundy, A., Zhang, J., Li, H., Baishen, R., Danysz, W., Bézard, E., & Cenci, M. A. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.05.001 · Cited by 153 · see citing works

Probiotics for Parkinson’s Disease

Gazerani, P. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20174121 · Cited by 152 · see citing works

Parkinson’s Disease: The Emerging Role of Gut Dysbiosis, Antibiotics, Probiotics, and Fecal Microbiota Transplantation

Dutta, S., Verma, S., Jain, V., Surapaneni, B. K., Vinayek, R., Phillips, L. E., & Nair, P. P. (2019) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm19044 · Cited by 149 · see citing works

Gut microbiota from persons with attention-deficit/hyperactivity disorder affects the brain in mice

Tengeler, A. C., Dam, S. A., Wiesmann, M., Naaijen, J., van Bodegom, M., Belzer, C., Dederen, P. J. W. C., Verweij, V. G. M., Franke, B., Kozicz, T., et al. (2020) · Microbiome · doi:10.1186/s40168-020-00816-x · Cited by 147 · see citing works

Fecal microbiota transplantation associated with 10 years of stability in a patient with SPMS

Makkawi, S., Camara-Lemarroy, C. R., & Metz, L. M. (2018) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000000459 · Cited by 144 · see citing works

Toll-like receptors and their therapeutic potential in Parkinson’s disease and α-synucleinopathies

Kouli, A., Horne, C. B., & Williams-Gray, C. H. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.06.042 · Cited by 143 · see citing works

Deep brain stimulation in early-stage Parkinson disease

Hacker, M. L., Turchan, M., Heusinkveld, L. E., Currie, A. D., Millan, S. H., Molinari, A. L., Konrad, P. E., Davis, T. L., Phibbs, F. T., Hedera, P., et al. (2020) · Neurology · doi:10.1212/wnl.0000000000009946 · Cited by 143 · see citing works

Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: modulation of histone deacetylase activity

Sharma, S., Taliyan, R., & Singh, S. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.05.052 · Cited by 142 · see citing works

Gut Metagenomics-Derived Genes as Potential Biomarkers of Parkinson’s Disease

Qian, Y., Yang, X., Xu, S., Huang, P., Li, B., Du, J., He, Y., Su, B., Xu, L.-M., Wang, L., et al. (2020) · Brain · doi:10.1093/brain/awaa201 · Cited by 139 · see citing works

Nonmotor gastrointestinal disorders in older patients with Parkinson&amp;rsquo;s disease: is there hope?

Georgescu, D., Ancusa, O., Georgescu, L., Ionita, I., & Reisz, D. (2016) · Clinical Interventions in Aging · doi:10.2147/cia.s106284 · Cited by 138 · see citing works

Are Dopamine Oxidation Metabolites Involved in the Loss of Dopaminergic Neurons in the Nigrostriatal System in Parkinson’s Disease?

Herrera, A., Muñoz, P., Steinbusch, H. W. M., & Segura‐Aguilar, J. (2017) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.7b00034 · Cited by 135 · see citing works

Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes

Liu, C., Kurokawa, R., Fujino, M., Hirano, S., Sato, B., & Li, X. (2014) · Scientific Reports · doi:10.1038/srep05485 · Cited by 133 · see citing works

Probiotics: Role in Pathophysiology and Prevention in Necrotizing Enterocolitis

Martin, C. R., & Walker, W. A. (2008) · Seminars in Perinatology · doi:10.1053/j.semperi.2008.01.006 · Cited by 132 · see citing works

Mechanisms underlying immune effects of dietary oligosaccharides

Jeurink, P. V., van Esch, B. C., Rijnierse, A., Garssen, J., & Knippels, L. M. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.038596 · Cited by 129 · see citing works

Effect of Probiotic <i>Lactobacillus salivarius</i> UBL S22 and Prebiotic Fructo-oligosaccharide on Serum Lipids, Inflammatory Markers, Insulin Sensitivity, and Gut Bacteria in Healthy Young Volunteers: A Randomized Controlled Single-Blind Pilot Study

Rajkumar, H., Kumar, M., Das, N., Kumar, S. N., Challa, H. R., & Nagpal, R. (2015) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248414555004 · Cited by 128 · see citing works

Parkinson’s disease and bacteriophages as its overlooked contributors

Tetz, G. V., Brown, S. M., Hao, Y., & Tetz, V. (2018) · Scientific Reports · doi:10.1038/s41598-018-29173-4 · Cited by 126 · see citing works

Use of pre-, pro- and synbiotics in patients with acute pancreatitis: A meta-analysis

Zhang, M. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i31.3970 · Cited by 116 · see citing works

Plasma Short‐Chain Fatty Acids in Patients With Parkinson's Disease

Shin, C., Lim, Y., Lim, H., & Ahn, T. (2020) · Movement Disorders · doi:10.1002/mds.28016 · Cited by 116 · see citing works

Meta‐analysis: Association of <i>Helicobacter pylori</i> infection with Parkinson's diseases

Shen, X., Yang, H., Wu, Y., Zhang, D., & Jiang, H. (2017) · Helicobacter · doi:10.1111/hel.12398 · Cited by 114 · see citing works

Specificity of catecholamine-induced growth in Escherichia coli O157:H7, Salmonella enterica and Yersinia enterocolitica

Freestone, P. P. E., Haigh, R. D., & Lyte, M. (2007) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2006.00619.x · Cited by 110 · see citing works

Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson’s disease in rats

Ito, M., Hirayama, M., Yamai, K., Goto, S., Ito, M., Ichihara, M., & Ohno, K. (2012) · Medical Gas Research · doi:10.1186/2045-9912-2-15 · Cited by 110 · see citing works

Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction

Yu, Z., Shi, M. Y., Stewart, T., Fernagut, P., Huang, Y. X. R., Tian, C., Dehay, B., Atik, A., Yang, D., Giorgi, F. D., et al. (2020) · Brain · doi:10.1093/brain/awaa110 · Cited by 108 · see citing works

The gut microbiome in Parkinson's disease: A culprit or a bystander?

Keshavarzian, A., Engen, P. A., Bonvegna, S., & Cilia, R. (2020) · Progress in brain research · doi:10.1016/bs.pbr.2020.01.004 · Cited by 104 · see citing works

Probiotics and Prebiotics as a Therapeutic Strategy to Improve Memory in a Model of Middle-Aged Rats

Romo‐Araiza, A., Gutiérrez-Salmeán, G., Galván, E. J., Hernández‐Frausto, M., Herrera‐López, G., Parra, H. R., García-Contreras, V., Fernández-Presas, A. M., Jasso‐Chávez, R., Borlongan, C. V., et al. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00416 · Cited by 103 · see citing works

Brain Autoimmunity and Intestinal Microbiota: 100 Trillion Game Changers

Wekerle, H. (2017) · Trends in Immunology · doi:10.1016/j.it.2017.03.008 · Cited by 101 · see citing works

The Effects of Probiotic Supplementation on Gene Expression Related to Inflammation, Insulin and Lipid in Patients with Parkinson's Disease: A Randomized, Double-blind, PlaceboControlled Trial.

Borzabadi, S., Oryan, S., Eidi, A., Aghadavod, E., Kakhaki, R. D., Tamtaji, O. R., Taghizadeh, M., & Asemi, Z. (2018) · PubMed · Cited by 101 · see citing works

Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis

Zhang, J., Yi, M., Zha, L., Chen, S., Li, Z., Li, C., Gong, M., Deng, H. X., Chu, X., Chen, J., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147218 · Cited by 100 · see citing works

Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway

Qiao, C.-M., Sun, M., Jia, X.-B., Shi, Y. W., Zhang, B.-P., Zhou, Z.-L., Zhao, L., Cui, C., & Shen, Y. (2019) · Experimental Cell Research · doi:10.1016/j.yexcr.2019.111772 · Cited by 99 · see citing works

Selegiline: a molecule with innovative potential

Tábi, T., Vécsei, L., Youdim, M. B. H., Riederer, P. F., & Szökő, É. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-019-02082-0 · Cited by 99 · see citing works

Alteration of the fecal microbiota in North-Eastern Han Chinese population with sporadic Parkinson’s disease

Li, F., Wang, P., Chen, Z., Sui, X., Xie, X., & Zhang, J. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134297 · Cited by 97 · see citing works

Rapid and Sustained Long‐Term Decrease of Fecal Short‐Chain Fatty Acids in Critically Ill Patients With Systemic Inflammatory Response Syndrome

Yamada, T., Shimizu, K., Ogura, H., Asahara, T., Nomoto, K., Yamakawa, K., Hamasaki, T., Nakahori, Y., Ohnishi, M., Kuwagata, Y., et al. (2014) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607114529596 · Cited by 93 · see citing works

Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model

Tetz, G. V., & Tetz, V. (2016) · Gut Pathogens · doi:10.1186/s13099-016-0109-1 · Cited by 93 · see citing works

Sodium Butyrate Exacerbates Parkinson’s Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model

Qiao, C.-M., Sun, M., Jia, X.-B., Yang, L., Zhang, B.-P., Zhao, L., Shi, Y. W., Zhou, Z.-L., Zhu, Y., Cui, C., et al. (2020) · Neurochemical Research · doi:10.1007/s11064-020-03074-3 · Cited by 92 · see citing works

Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury

Ulusoy, A., Musgrove, R. E., Rusconi, R., Klinkenberg, M., Helwig, M., Schneider, A., & Monte, D. A. D. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0198-y · Cited by 91 · see citing works

Quantification of hydrogen production by intestinal bacteria that are specifically dysregulated in Parkinson's disease

Suzuki, A., Ito, M., Hamaguchi, T., Mori, H., Takeda, Y., Baba, R., Watanabe, T., Kurokawa, K., Asakawa, S., Hirayama, M., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0208313 · Cited by 90 · see citing works

Long-term Outcome of Gastric Per-Oral Endoscopic Pyloromyotomy in Treatment of Gastroparesis

Abdelfatah, M. M., Noll, A. G., Kapil, N., Shah, R., Li, L., Nustas, R., Li, B., Luo, H., Chen, H., Xia, L., et al. (2020) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2020.05.039 · Cited by 87 · see citing works

Inadequate Production of H2 by Gut Microbiota and Parkinson Disease

Ostojić, S. M. (2018) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2018.02.006 · Cited by 83 · see citing works

Therapies to modulate gut microbiota: Past, present and future

Gupta, A., Saha, S., & Khanna, S. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i8.777 · Cited by 83 · see citing works

Potential of Prebiotic Butyrogenic Fibers in Parkinson's Disease

Cantu-Jungles, T. M., Rasmussen, H. E., & Hamaker, B. R. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00663 · Cited by 81 · see citing works

Microbiome, Parkinson’s Disease and Molecular Mimicry

Miraglia, F., & Colla, E. (2019) · Cells · doi:10.3390/cells8030222 · Cited by 81 · see citing works

Parkinson's Disease: A Comprehensive Analysis of Fungi and Bacteria in Brain Tissue

Pisa, D., Alonso, R., & Carrasco, L. (2020) · International Journal of Biological Sciences · doi:10.7150/ijbs.42257 · Cited by 80 · see citing works

Epigenome targeting by probiotic metabolites

Licciardi, P. V., Wong, S., Tang, M. L. K., & Karagiannis, T. C. (2010) · Gut Pathogens · doi:10.1186/1757-4749-2-24 · Cited by 79 · see citing works

Antipsychotic Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD): Management of Extrapyramidal Side Effects

Ohno, Y., Kunisawa, N., & Shimizu, S. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01045 · Cited by 77 · see citing works

Clinical implications of gastric complications on levodopa treatment in Parkinson’s disease

Pfeiffer, R. F., Isaacson, S. H., & Pahwa, R. (2020) · Parkinsonism &amp; Related Disorders · doi:10.1016/j.parkreldis.2020.05.001 · Cited by 77 · see citing works

Helicobacter pylori Eradication in Parkinson's Disease: A Randomized Placebo‐Controlled Trial

Tan, A. H., Lim, S., Mahadeva, S., Loke, M. F., Tan, J. Y., Ang, B. H., Chin, K. P., Adnan, A. F. M., Ong, S. M. C., Ibrahim, A. I., et al. (2020) · Movement Disorders · doi:10.1002/mds.28248 · Cited by 76 · see citing works

Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile

Gutin, L. S., Piceno, Y. M., Fadrosh, D. W., Lynch, K. V., Zydek, M., Kassam, Z., LaMere, B. J., Terdiman, J. P., Ma, A. I., Somsouk, M., et al. (2019) · United European Gastroenterology Journal · doi:10.1177/2050640619845986 · Cited by 73 · see citing works

Overlapping Mechanisms of Action of Brain-Active Bacteria and Bacterial Metabolites in the Pathogenesis of Common Brain Diseases

Eicher, T. P., & Mohajeri, M. H. (2022) · Nutrients · doi:10.3390/nu14132661 · Cited by 148 · see citing works

An updated overview on the relationship between human gut microbiome dysbiosis and psychiatric and psychological disorders

Borrego-Ruiz, A., & Borrego, J. J. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110861 · Cited by 106 · see citing works

Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside

Ma, Y., Li, X., Yu, J., & Wang, Y. (2024) · Translational Neurodegeneration · doi:10.1186/s40035-024-00404-1 · Cited by 87 · see citing works

Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson’s Disease

Guo, T.-T., Zhang, Z., Sun, Y., Zhu, R.-Y., Wang, F.-X., Ma, L.-J., Jiang, L., & Liu, H.-D. (2023) · Nutrients · doi:10.3390/nu15040930 · Cited by 82 · see citing works

Relationship Between Short-chain Fatty Acids and Parkinson’s Disease: A Review from Pathology to Clinic

Duan, W.-X., Wang, F., Liu, J., & Liu, C. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-023-01123-9 · Cited by 78 · see citing works

Review of microbiota gut brain axis and innate immunity in inflammatory and infective diseases

Yuan, C., He, Y., Xie, K., Feng, L., Gao, S., & Cai, L. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1282431 · Cited by 82 · see citing works

Inflammatory microbes and genes as potential biomarkers of Parkinson’s disease

Nie, S., Wang, J., Deng, Y., Ye, Z., & Ge, Y. (2022) · npj Biofilms and Microbiomes · doi:10.1038/s41522-022-00367-z · Cited by 73 · see citing works

Respiratory tract infections and gut microbiome modifications: A systematic review

Woodall, C. A., McGeoch, L. J., Hay, A. D., & Hammond, A. (2022) · PLoS ONE · doi:10.1371/journal.pone.0262057 · Cited by 64 · see citing works

Gut-Brain Axis a Key Player to Control Gut Dysbiosis in Neurological Diseases

Pan, I., Issac, P. K., Rahman, M. M., Guru, A., & Arockiaraj, J. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03691-3 · Cited by 60 · see citing works

Metagenomics of the Gut Microbiome in Parkinson's Disease: Prodromal Changes

Palacios, N., Wilkinson, J., Bjornevik, K., Schwarzschild, M. A., McIver, L., Ascherio, A., & Huttenhower, C. (2023) · Annals of Neurology · doi:10.1002/ana.26719 · Cited by 59 · see citing works

Neuroprotective effects of an engineered Escherichia coli Nissle 1917 on Parkinson's disease in mice by delivering GLP ‐1 and modulating gut microbiota

Wu, H., Wei, J., Zhao, X., Liu, Y., Chen, Z., Wei, K., Lu, J., Chen, W., Jiang, M., Li, S., et al. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10351 · Cited by 57 · see citing works

Gastrodia elata polysaccharide alleviates Parkinson's disease via inhibiting apoptotic and inflammatory signaling pathways and modulating the gut microbiota

Gan, Q., Peng, M., Wei, H., Chen, L., Chen, X.-Y., Li, Z.-H., An, G., & Ma, Y. (2024) · Food & Function · doi:10.1039/d3fo05169b · Cited by 57 · see citing works

The roles of gut microbiota and its metabolites in diabetic nephropathy

Zhao, H., Yang, C.-E., Liu, T., Zhang, M., Niu, Y., Wang, M., & Yu, J. Q. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1207132 · Cited by 55 · see citing works

Associations between gut microbiota and Parkinson disease: A bidirectional Mendelian randomization analysis

Li, J., Li, J., Tang, B., & Guo, J. (2023) · European Journal of Neurology · doi:10.1111/ene.15848 · Cited by 53 · see citing works

The pathogenesis and treatment mechanism of Parkinson's disease from the perspective of traditional Chinese medicine

Chen, P., Zhang, J., Wang, C., Chai, Y., Wu, A., Huang, N., & Wang, L. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154044 · Cited by 50 · see citing works

Gut Microbiome and Mycobiome Alterations in an In Vivo Model of Alzheimer’s Disease

D’Argenio, V., Veneruso, I., Gong, C., Cecarini, V., Bonfili, L., & Eleuteri, A. M. (2022) · Genes · doi:10.3390/genes13091564 · Cited by 46 · see citing works

Differences in the Composition of Gut Microbiota between Patients with Parkinson’s Disease and Healthy Controls: A Cohort Study

Zapała, B., Stefura, T., Wójcik-Pędziwiatr, M., Kabut, R., Bałajewicz-Nowak, M., Milewicz, T., Dudek, A., Stój, A., & Rudzińska-Bar, M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10235698 · Cited by 44 · see citing works

Exploring the gut-brain Axis: Potential therapeutic impact of Psychobiotics on mental health

Cocean, A.-M., & Vodnar, D. C. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111073 · Cited by 48 · see citing works

Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice

Xu, R.-C., Miao, W.-T., Xu, J., Xu, W. V., Liu, M.-R., Ding, S., Jian, Y.-X., Lei, Y.-H., Yan, N., & Liu, H.-D. (2022) · Nutrients · doi:10.3390/nu14194163 · Cited by 39 · see citing works

Comprehensive Review on Potential Signaling Pathways Involving the Transfer of α-Synuclein from the Gut to the Brain That Leads to Parkinson’s Disease

Kumari, S., Taliyan, R., & Dubey, S. K. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.2c00730 · Cited by 37 · see citing works

A Narrative Review on the Advance of Probiotics to Metabiotics

Jang, H. J., Lee, N., & Paik, H. (2024) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2311.11023 · Cited by 38 · see citing works

The role of the microbiota-gut-brain axis and intestinal microbiome dysregulation in Parkinson’s disease

Li, Q., Meng, L., Chen, L., Shi, X., Tu, L., Zhou, Q. G., Yu, J.-L., Liao, X., Zeng, Y., & Yuan, Q. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1185375 · Cited by 36 · see citing works

Emerging insights between gut microbiome dysbiosis and Parkinson’s disease: Pathogenic and clinical relevance

Bi, M., Feng, L., He, J., Liu, C., Wang, Y., Jiang, H., & Liu, S. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101759 · Cited by 32 · see citing works

The link between increased Desulfovibrio and disease severity in Parkinson’s disease

Nie, S., Jing, Z., Wang, J., Deng, Y., Zhang, Y., Ye, Z., & Ge, Y. (2023) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-023-12489-1 · Cited by 31 · see citing works

Gut dysfunction may be the source of pathological aggregation of alpha-synuclein in the central nervous system through Paraquat exposure in mice

Wang, K., Zhang, C., Zhang, B., Li, G., Shi, G., Cai, Q., & Huang, M. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.114152 · Cited by 30 · see citing works

Role of the microbiota in inflammation-related related psychiatric disorders

Zhou, L., Wu, Q. J., Jiang, L., Rao, J., Gao, J., Zhao, F., & Wang, X. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1613027 · Cited by 30 · see citing works

The relationship between Parkinson’s disease and gastrointestinal diseases

Zeng, J., Wang, X., Pan, F., & Mao, Z. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.955919 · Cited by 26 · see citing works

Interplay of human gastrointestinal microbiota metabolites: Short-chain fatty acids and their correlation with Parkinson’s disease

Liu, J., Chen, Q., & Su, R. (2024) · Medicine · doi:10.1097/md.0000000000037960 · Cited by 25 · see citing works

The Pathology and Physiology of Ileostomy

Ma, H., Li, X., Yang, H., Qiu, Y., & Xiao, W. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.842198 · Cited by 25 · see citing works

Aging, testosterone, and neuroplasticity: friend or foe?

Saleki, K., Banazadeh, M., Saghazadeh, A., & Rezaei, N. (2022) · Reviews in the Neurosciences · doi:10.1515/revneuro-2022-0033 · Cited by 25 · see citing works

Sleep deprivation accelerates Parkinson's disease via modulating gut microbiota associated microglial activation and oxidative stress

Zhu, W., Hu, Y., Shi, Y., Bao, H., Cheng, X., Jiang, M., Peng, Z., Song, J., Fang, F., Jian, C., et al. (2025) · Microbiological Research · doi:10.1016/j.micres.2025.128077 · Cited by 24 · see citing works

Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway

Ma, X., Li, M., Zhang, Y., Xu, T., Zhou, X., Qian, M., Yang, Z., & Han, X. (2025) · eLife · doi:10.7554/elife.92906.5 · Cited by 23 · see citing works

The link between the gut microbiome, inflammation, and Parkinson’s disease

Nie, S., & Ge, Y. (2023) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-023-12789-6 · Cited by 23 · see citing works

Multidirectional associations between the gut microbiota and Parkinson’s disease, updated information from the perspectives of humoral pathway, cellular immune pathway and neuronal pathway

Jia, X., Chen, Q., Zhang, Y., & Asakawa, T. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1296713 · Cited by 22 · see citing works

Gut Microbiota-Based Interventions for Parkinson’s Disease: Neuroprotective Mechanisms and Current Perspective

Kumar, D., Bishnoi, M., Kondepudi, K. K., & Sharma, S. S. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-024-10433-x · Cited by 21 · see citing works

Gut microbiota-associated taurine metabolism dysregulation in a mouse model of Parkinson’s disease

Cui, C., Song, H., Han, Y., Yu, H., Li, H., Yang, Y., & Zhang, B. (2023) · mSphere · doi:10.1128/msphere.00431-23 · Cited by 21 · see citing works

Gut microbiota and tuberculosis infection: interaction and therapeutic potential

Chai, Y., Li, M., Deng, X., Ma, C., Zhou, N., Chen, Y., Yao, Y., Li, K. C., Gong, W., & Lei, H. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2531201 · Cited by 21 · see citing works

Dietary Galacto-oligosaccharides Ameliorate Atopic Dermatitis-like Skin Inflammation and Behavioral Deficits by Modulating Gut Microbiota–Brain–Skin Axis

Tang, L., Cao, X., Chen, S., Jiang, X., Li, D., & Chen, G. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c00205 · Cited by 20 · see citing works

Microbiota mitochondria disorders as hubs for early age-related macular degeneration

Fehér, J., Élő, Á., István, L., Nagy, Z. Z., Radak, Z. O., Scuderi, G., Artico, M., & Kovács, I. (2022) · GeroScience · doi:10.1007/s11357-022-00620-5 · Cited by 19 · see citing works

The alteration of intestinal mucosal α-synuclein expression and mucosal microbiota in Parkinson’s disease

Shi, J., Wang, Y., Chen, D., Xu, X., Li, W., Li, K., He, J., Su, W., & Luo, Q. (2023) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-023-12410-w · Cited by 19 · see citing works

Memory in Misfire: The Gut Microbiome-Trained Immunity Circuit in Inflammatory Bowel Diseases

Yang, B., Wu, J., Hou, X., Bai, T., & Liu, S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199663 · Cited by 18 · see citing works

Metabolic modeling links gut microbiota to metabolic markers of Parkinson’s disease

Hensen, T., & Thiele, I. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2554195 · Cited by 15 · see citing works

Effect of the gut microbiome in glaucoma risk from the causal perspective

Wu, Y., Shi, R., Chen, H., Zhang, Z., Bao, S., Qu, J., & Zhou, M. (2024) · BMJ Open Ophthalmology · doi:10.1136/bmjophth-2023-001547 · Cited by 16 · see citing works

Higher dietary butyrate intake is associated with better cognitive function in older adults: evidence from a cross-sectional study

Tu, J., Zhang, J., & Chen, G. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1522498 · Cited by 16 · see citing works

Infectious Agents as Potential Drivers of α‐Synucleinopathies

Linard, M., Ravier, A., Mougué, L., Grgurina, I., Boutillier, A., Foubert‐Samier, A., Blanc, F., & Helmer, C. (2022) · Movement Disorders · doi:10.1002/mds.28925 · Cited by 16 · see citing works

Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathwayPreprint

Ma, X., Li, M., Zhang, Y., Xu, T., Zhou, X., Qian, M., Yang, Z., & Han, X. (2023) · eLife · doi:10.7554/elife.92906 · Cited by 16 · see citing works

Microbiome Alterations and Alzheimer’s Disease: Modeling Strategies with Transgenic Mice

López-Villodres, J. A., Escamilla, A., Mercado-Sáenz, S., Alba-Tercedor, C., Rodríguez‐Pérez, L., Arranz‐Salas, I., Sanchez-Varo, R. M., & Bermúdez, D. (2023) · Biomedicines · doi:10.3390/biomedicines11071846 · Cited by 16 · see citing works

Multi-omics analysis of gut-brain axis reveals novel microbial and neurotransmitter signatures in patients with arteriosclerotic cerebral small vessel disease

Huang, J., Liu, S., Li, P., Wei, L., Lin, G., Lin, J., Luo, Y., Liu, Y., Mao, Y., Ruan, H., et al. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107385 · Cited by 13 · see citing works

Exploring the role of gut microbiota in Parkinson’s disease: insights from fecal microbiota transplantation

Guo, M., Gao, H., Wang, Y., & Xiang, Y. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1574512 · Cited by 13 · see citing works

The Interaction Between Nutraceuticals and Gut Microbiota: a Novel Therapeutic Approach to Prevent and Treatment Parkinson’s Disease

Yao, L., Yang, Y., Yang, X., & Rezaei, M. J. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04151-2 · Cited by 13 · see citing works

Neuronal control of microglia through the mitochondria

Pereira-Santos, A. R., Candeias, E., Magalhães, J. D., Empadinhas, N., Esteves, A. R., & Cardoso, S. M. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167167 · Cited by 13 · see citing works

Partially Hydrolyzed Guar Gum Intake Supports the Gut Microbiota and Attenuates Inflammation during Influenza H1N1 Virus Infection in Mice

Kato, T., Kamiya, S., Narasaki, S., Sumii, A., Tsutsumi, Y. M., Machida, K., Hara, K., Izumi-Mishima, Y., Tsutsumi, R., & Sakaue, H. (2023) · Nutrients · doi:10.3390/nu15194252 · Cited by 13 · see citing works

The gut microbiota influences neurodegenerative diseases through the gut-brain axis: molecular mechanisms and effects on immune function

Yang, J., Song, X., Yan, S., Li, Q., & Yang, W. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1739329 · Cited by 12 · see citing works

The Determination of Trimethylamine N-Oxide and Organic Acids Connected with Gut Microbiota in the Urine of Parkinson’s Disease Patients: A Pilot Study

Gątarek, P., Pawelczyk, M., Bobrowska‐Korczak, B., Giebułtowicz, J., Glabinski, A. R., & Kałużna‐Czaplińska, J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26104575 · Cited by 11 · see citing works

New Pieces for an Old Puzzle: Approaching Parkinson’s Disease from Translatable Animal Models, Gut Microbiota Modulation, and Lipidomics

Moreno, L. O., Bagüés, A., Martı́nez, V., & Abalo, R. (2023) · Nutrients · doi:10.3390/nu15122775 · Cited by 11 · see citing works

The Intricate Interplay: Microbial Metabolites and the Gut‐Liver‐Brain Axis in Parkinson's Disease

Kishanchand, D. K., A., A. K. K., Chandrababu, K., Philips, C. A., Sivan, U., & Chakrapani, P. S. B. (2025) · Journal of Neuroscience Research · doi:10.1002/jnr.70016 · Cited by 11 · see citing works

The role of the gut microbiota in neuropsychiatric disorders and therapy

Zhang, F., Ding, K., Zhang, L., Liu, D., Dong, X., Wang, M., Zhou, F.-L., Sun, Y., Zhang, W., Yu, Y., et al. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102894 · Cited by 11 · see citing works

Development of a H2S-responsive NIR Fluorescent Probe for H2S Detection and H2S Releasing Monitoring From Prodrug

Wu, M., Wang, S., Hai, W., Lu, X., & Li, P. (2023) · Journal of Fluorescence · doi:10.1007/s10895-023-03187-2 · Cited by 9 · see citing works

Plasma Metabolites as Mediators Between Gut Microbiota and Parkinson’s Disease: Insights from Mendelian Randomization

Chen, J., Zhu, L., Wang, F., Zhu, Y., Chen, J., Liang, C., Liu, B., Pang, A., & Yang, X. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04765-0 · Cited by 8 · see citing works

Alterations of Gut Microbiota and Microbial Metabolites in Parkinson’s Disease: A Systematic Review

Davoody, S., Vakili, K. G., Jazi, K., Fathi, M., Heidari‐Foroozan, M., Mofidi, S. A., Taremi, M., Taherkhani, A., Azadnajafabad, S., Hojjatipour, F., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05598-7 · Cited by 7 · see citing works

Deciphering the microbial map and its implications in the therapeutics of neurodegenerative disorder

Vashishth, S., Ambasta, R. K., & Kumar, P. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102466 · Cited by 7 · see citing works

Concomitant gut dysbiosis and defective gut barrier serve as the bridges between hypercortisolism and chronic systemic inflammation in Cushing’s disease

Lin, B. C., Melnikov, V., Guo, S., Cao, Z., Ye, Z., Ye, Z., Ji, C., Chen, J., Wang, J., Zhang, H., et al. (2024) · European Journal of Endocrinology · doi:10.1093/ejendo/lvae139 · Cited by 7 · see citing works

Age-driven dysbiosis: gut microbiota in the pathogenesis and treatment of aging disorders

Kopalli, S. R., Wankhede, N. L., Rahangdale, S. R., Sammeta, S. S., Aglawe, M. M., Koppula, S., Taksande, B. G., Upaganlawar, A., Umekar, M. J., & Kale, M. B. (2026) · Biogerontology · doi:10.1007/s10522-026-10389-1 · Cited by 6 · see citing works

Hydrogen Sulfide (H2S) Generated in the Colon Induces Neuropathic Pain by Activating Spinal NMDA Receptors in a Rodent Model of Chronic Constriction Injury

Wang, J., Zhang, N., Liu, H.-Z., Wang, J.-L., Zhang, Y., Su, D.-D., Zhang, L.-M., Li, B., Miao, H., & Miao, J. (2025) · Neurochemical Research · doi:10.1007/s11064-025-04342-w · Cited by 6 · see citing works

Frontiers and future perspectives of neuroimmunology

Qi, H., Duan, S., Xu, Y., & Zhang, H. (2022) · Fundamental Research · doi:10.1016/j.fmre.2022.10.002 · Cited by 5 · see citing works

Integrated Microbiome and Metabolome Analysis Reveals Hypothalamic‐Comorbidities Related Signatures in Craniopharyngioma

Lin, B. C., Ye, Z., Cao, Z., Ye, Z., Yu, Y., Jiang, W., Guo, S., Melnikov, V., Zhou, P., Ji, C., et al. (2024) · Advanced Science · doi:10.1002/advs.202400684 · Cited by 5 · see citing works

Retrospective analysis of diet and gut microbiota diversity and clinical pharmacology outcomes in patients with Parkinsonism syndrome

Hu, Y., Wang, H., Zhong, Y., & Sun, Y. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e38645 · Cited by 5 · see citing works

Neuroimmune modulators derived from natural products: Mechanisms and potential therapies

Feng, W.-D., Liu, D.-N., Shang, Y.-F., Zhang, W., Xu, S., Feng, D.-H., & Wang, Y. (2025) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2025.108830 · Cited by 5 · see citing works

Exercise as a multitarget therapy: modulating myokines, neurotrophins, and inflammation in Parkinson’s disease

Li, W., Yang, J.-H., Liu, L., Ding, S., Yu, B., Jiang, L., Yan, N., & Liu, H.-D. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1580029 · Cited by 5 · see citing works

Ingestible electronic capsules for in situ sensing of diverse biomarkers

Zhang, C., Song, H., Zeng, J., Chen, J., Ni, C.-J., Chung, H.-U., Xu, K., Ying, B.-B., & Nan, K. (2025) · Device · doi:10.1016/j.device.2025.100935 · Cited by 4 · see citing works

Unraveling the Relation of Parkinson's Disease and Metabolites: A Combined Analysis of Stool and Plasma Metabolites Based on Untargeted Metabolomics Technology

Liu, S., Zhao, Q., Tang, J., Li, X., Wang, J., Zhao, Y., Yang, Z., Pan, X., Xiang, R. H., Tian, J., et al. (2025) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70424 · Cited by 4 · see citing works

Exploring the relationship between novel Coronavirus pneumonia and Parkinson’s disease

Xi, X., & Han, L. (2022) · Medicine · doi:10.1097/md.0000000000031813 · Cited by 4 · see citing works

Akkermansia muciniphila identified as key strain to function in pathogen invasion and intestinal stem cell proliferation through Wnt signaling pathwayPreprint

Ma, X., Li, M., Xu, T., Zhou, X., Qian, M., Yang, Z., Cao, K., & Han, X. (2023) · eLife · doi:10.7554/elife.92906.1 · Cited by 4 · see citing works

From dysbiosis to dysfunction: specific gut microbes and metabolites in the pathogenesis of Parkinson’s disease

Chi, F., Chen, K., Yin, Y., Hakovirta, J. R., & Saris, P. E. J. (2026) · Sustainable Microbiology · doi:10.1093/sumbio/qvag002 · Cited by 5 · see citing works

Gut microbiota changes are associated with abnormal metabolism activity in children and adolescents with obsessive-compulsive disorder

Dai, J., Li, M., He, J., Duan, L., Zhu, X., Liu, L., Meng, M., Shao, X., & Zhu, G. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.12.041 · Cited by 3 · see citing works

Associations of digestive diseases exposure and lifestyle factors with Parkinson’s disease

Yang, K., Zeng, R., Zheng, Y., Zhong, S., Wang, J., Yu, X., Zhong, H., Chen, X., Shi, Y., Lin, F., et al. (2025) · npj Parkinson s Disease · doi:10.1038/s41531-025-01098-6 · Cited by 3 · see citing works

Research progress on natural products in regulating the gut microbiota in Parkinson’s disease

Jia, Y., Zhang, Y., Tai, X., Zhao, T., Zhang, H., & Zhou, H. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1667694 · Cited by 4 · see citing works

High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health

Ali, I., Martin, J., Zárate-Potes, A., & Benedetto, A. (2022) · Journal of Visualized Experiments · doi:10.3791/63860 · Cited by 4 · see citing works

Fecal microbiota transplantation for glaucoma; a potential emerging treatment strategy

Ebrahimi, R., Farsi, Y., & Nejadghaderi, S. A. (2024) · Current Research in Microbial Sciences · doi:10.1016/j.crmicr.2024.100314 · Cited by 4 · see citing works

Gut microbiome and diabetic kidney disease: Insights from Mendelian randomization and genetic correlations

Yang, K., Zhao, Z., Yin, Y., Liu, Y., & Wu, X. (2025) · Medicine · doi:10.1097/md.0000000000042492 · Cited by 2 · see citing works

Effects of gut microbiota on cognitive impairment in Parkinson’s disease: a comprehensive Mendelian randomization and case–control study

Feng, Y., Chang, Q., Zhou, H., Zhang, W., Xie, L., Deng, X., Chen, T., & Liu, W. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1620449 · Cited by 2 · see citing works

WuMei-pill alleviates Parkinson's disease induced by dopamine neuron damage in mice by regulating the gut-brain-microbiome axis

Zhang, Z., Shen, L., Bai, Y., Li, S., & Wang, S. (2025) · Journal of Radiation Research and Applied Sciences · doi:10.1016/j.jrras.2025.101632 · Cited by 2 · see citing works

Association Between Blood-Brain Barrier Disruption and Gut Microbiota Dysbiosis in Parkinson’s Disease

Yao, W., Liu, L., Wang, J., Chen, S., Zhang, C., Liao, R., Wang, Y., Ou, K., Jiang, L., Yu, Y., et al. (2026) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-026-01738-2 · Cited by 1 · see citing works

New insights in non-motor symptoms in Parkinson’s disease

Falup‐Pecurariu, C., Fanciulli, A., Borgohain, R., Chaudhuri, К. R., & Metta, V. (2024) · Frontiers research topics · doi:10.3389/978-2-8325-4722-9 · Cited by 1 · see citing works

Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathwayPreprint

Ma, X., Li, M., Zhang, Y., Xu, T., Zhou, X., Qian, M., Yang, Z., & Han, X. (2024) · eLife · doi:10.7554/elife.92906.2 · Cited by 1 · see citing works

Neuromicrobiology of Neurodegenerative Diseases:Preprint

Nandi, A., Nandi, A., Kaur, A., Ghai, S., Singh, G., & Tiwari, A. (2023) · doi:10.14293/pr2199.000546.v1

Research and treatment discussions regarding the potential impact of gut microbiota on Parkinson's disease

Tang, H. (2023) · International Journal of Frontiers in Medicine · doi:10.25236/ijfm.2023.051216

Effects of acupuncture on Parkinson's disease-related constipation and roles of gut microbial ecology: study protocol for a randomized controlled clinical trialPreprint

Lei, S., Fan, J., Quan, J., Li, Y., Cen, M., Xu, X., Liu, X., Wu, S., Liao, K., Lin, S., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4171150/v1

Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathwayPreprint

Ma, X., Li, M., Zhang, Y., Xu, T., Zhou, X., Qian, M., Yang, Z., & Han, X. (2024) · eLife · doi:10.7554/elife.92906.3

Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathwayPreprint

Ma, X., Meng, L., Zhang, Y., Xu, T., Zhou, X., Qian, M., Yang, Z., & Han, X. (2024) · eLife · doi:10.7554/elife.92906.4

Research Progress on the Relationship between Gut Microbiome and Parkinson’s Disease

力比奴尔·塞地尔丁, 克. (2024) · Advances in Clinical Medicine · doi:10.12677/acm.2024.14123217

Comorbidity of inflammatory bowel diseases and Parkinson’s disease

Трухан, Д. И., Konshu, N. V., & Олеговна, М. П. (2025) · Meditsinskiy sovet = Medical Council · doi:10.21518/ms2025-170

Effects and mechanisms of acupuncture for PIGD-subtype Parkinson’s disease via integration of fMRI and gut microbiota-metabolomics analysis: protocol for a prospective randomized controlled trial

Sheng, J., Xu, Y., Liu, T., Zhu, J., Mu, C., Zhai, L., Xu, S., Wang, H., Liu, X., Liu, T., et al. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1534165

Intestinal flora in aging: a scientific perspective on food intervention

Ye, X., Guan, Y., Chen, P., Zhu, J., Liu, Y., Chen, J., Zhu, K., Jin, Z., Luo, S., Cai, J., et al. (2025) · Food Science and Human Wellness · doi:10.26599/fshw.2025.9250713

Parkinson's Disease and Cancer: Mechanistic Insights and Therapeutic Opportunities From Cancer Neuroscience

Pan, T., Yuan, L., Zhao, R., Lu, L., Zhi, Y., Li, Y., Wu, M., & Huang, Y. (2025) · MedComm – Oncology · doi:10.1002/mog2.70044

Exploring the therapeutic potential of the gut microbiota metabolite 3‑indolepropionic acid in parkinson’s disease: a network pharmacology, molecular docking and cell viability study

Zheng, Q. G., Han, S., He, L., & Chen, Y. (2026) · Metabolic Brain Disease · doi:10.1007/s11011-026-01794-z

Stereoselective effects of nicotine enantiomers on the gut-brain axis and neuroinflammation in a mouse model of Parkinson’s disease

Liu, R. X., Ma, Y., Li, Y., Gao, X., Wang, S., Xu, L., Liu, G., Chen, H., Ji, M., & Hou, H. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1823372

The Human Microbiome in Airborne Particulate Matter–Associated Aging-Related Chronic Diseases: An Evidence-Stratified Review

Yang, Y., Liu, X., Wang, M., Zhu, X., Yang, B., Cao, J., Song, Y., & Jiang, G. (2026) · Environment & Health · doi:10.1021/envhealth.5c00852

Bidirectional mendelian randomization links circulating inflammation and gut microbiota to synucleinopathies, validated by probiotic modulation in a Parkinson’s disease mouse model

Zheng, X., Li, L., Huang, Z., & Zhou, L. (2026) · Brain Network Disorders · doi:10.1016/j.bnd.2026.06.001

Dysbiosis of gut microbiota and microbial metabolites in Parkinson's disease

Sun, M.-F., & Shen, Y.-Q. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.04.004 · Cited by 445 · see citing works

Parkinson's Disease and the Microbiota-Gut-Brain Axis: Metabolites, Mechanisms, and Innovative Therapeutic Strategies Targeting the Gut Microbiota

Zhao, R., Mu, B., Wang, D., XinHuang, Ma, Q., & Lu, M. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04584-9 · Cited by 19 · see citing works

From dysbiosis to dysfunction: specific gut microbes and metabolites in the pathogenesis of Parkinson’s disease

Chi, F., Chen, K., Yin, Y., Hakovirta, J. R., & Saris, P. E. J. (2026) · Sustainable Microbiology · doi:10.1093/sumbio/qvag002 · Cited by 5 · see citing works

The role of the gut microbiome in Parkinson’s disease

Metcalfe‐Roach, A., & Finlay, B. B. (2025) · Future Neurology · doi:10.1080/14796708.2025.2494981 · Cited by 6 · see citing works

Emerging insights between gut microbiome dysbiosis and Parkinson’s disease: Pathogenic and clinical relevance

Bi, M., Feng, L., He, J., Liu, C., Wang, Y., Jiang, H., & Liu, S. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101759 · Cited by 32 · see citing works