Using genetics for social science
Open accessAbstract
Social science genetics is concerned with understanding whether, how and why genetic differences between human beings are linked to differences in behaviours and socioeconomic outcomes. Our review discusses the goals, methods, challenges and implications of this research endeavour. We survey how the recent developments in genetics are beginning to provide social scientists with a powerful new toolbox they can use to better understand environmental effects, and we illustrate this with several substantive examples. Furthermore, we examine how medical research can benefit from genetic insights into social-scientific outcomes and vice versa. Finally, we discuss the ethical challenges of this work and clarify several common misunderstandings and misinterpretations of genetic research on individual differences. Harden and Koellinger discuss the goals, methods and challenges of social science genetics, which aims to unravel the genetic underpinnings of individual differences in social, behavioural and health outcomes.
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Genetic differences are a major confounder in many psychological and social phenomena.
“Genetic differences are a major confounder in many psychological and social phenomena35,36, but until recently this has been hard to account for because single genetic variants have very small effects.”
From The impact of digital media on children’s intelligence while controlling for genetic differences in cognition and socioeconomic background (2022) · cites this paper as [35]
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Self-citationBelsky, D. W., & Harden, K. P. (2019) · Current Directions in Psychological Science · doi:10.1177/0963721418807729 · Cited by 96 · see citing works
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A behavior genetic investigation of adolescent motherhood and offspring mental health problems.
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Self-citationThe Arrival of Social Science Genomics
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Why Have Tobacco Control Policies Stalled? Using Genetic Moderation to Examine Policy Impacts
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Mendelian randomization: the challenge of unobserved environmental confounds
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Using nature to understand nurture
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Self-citationVariable prediction accuracy of polygenic scores within an ancestry groupPreprint
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Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women
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The Biodemography of Human Reproduction and Fertility
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Genetic Risks for Chronic Conditions: Implications for Long-term Wellbeing
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Age at first birth in women is genetically associated with increased risk of schizophrenia
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Genetic Endowments and Wealth Inequality
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Self-citationNature still battles nurture in the haunting world of social genomics
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Flagged first, then by citations
Research works printed but not linked: 2
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- [114]Turley P Multi-trait analysis of genome-wide association summary statistics using MTAG. Nat. Genet. 50, 229– 237 (2018). 29292387 PMC5805593
Cited by
Sorted by citations
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Human brain anatomy reflects separable genetic and environmental components of socioeconomic status
Kweon, H., Aydogan, G., Dagher, A., Bzdok, D., Ruff, C. C., Nave, G., Farah, M. J., & Koellinger, P. D. (2022) · Science Advances · doi:10.1126/sciadv.abm2923 · Cited by 36 · see citing works
Self-citation
- Authors
- Harden, K. P., & Koellinger, P. D.
- Affiliations
- The University of Texas at Austin (US)
- Vrije Universiteit Amsterdam (NL)
- Corresponding author
- Harden, K. Paige
- Koellinger, Philipp D.
- Venue
- Nature Human Behaviour
- Published
- 2020-05-11
- Volume
- 4
- Issue
- 6
- Pages
- 567-576
- ISSN
- 2397-3374 (ISSN-L)
- PMC
- PMC8240138
- OpenAlex
- W3023331821
- Cited by
- 180
- References
- 118
- Citations by year
- 2026: 22 · 2025: 19 · 2024: 29 · 2023: 30 · 2022: 28 · 2021: 42 · 2020: 9
- FWCI
- 3.89
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Nature Human Behaviour (publishedVersion, public-domain)
- PubMed (publishedVersion)
- VU Research Portal (publishedVersion, other-oa)
- PubMed Central (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- John Templeton Foundation
- University of Texas at Austin
- Jacobs Foundation
- National Institute of Child Health and Human Development (HD042849)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R24HD042849, R01HD092548, R01HD083613, P2CHD042849)
- H2020 European Research Council (647648)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- behavioral genetics, socioeconomic outcomes, environmental effects, gene-environment interaction, individual differences, health outcomes, medical genetics, genetic research ethics
- MeSH terms
- Human Genetics, Humans, Psychology, Social, Social Mobility, Social Sciences, Multifactorial Inheritance, Genome-Wide Association Study
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