Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

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cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

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The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination

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Necroptosis in development, inflammation and disease

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Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

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The many roles of FAS receptor signaling in the immune system

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Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

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CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members

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FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis

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MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

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NF-κB Signals Induce the Expression of c-FLIP

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Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

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Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer’s disease

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RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

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RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

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RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3

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RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

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Activation of Necroptosis in Multiple Sclerosis

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TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

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NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling

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Microglia and Inflammation in Alzheimers Disease

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Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS

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The “Dying-Back” Phenomenon of Motor Neurons in ALS

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Neuroinflammation: Microglia and T Cells Get Ready to Tango

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RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease

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Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice

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