Cited by 741Nutritional Studies and DietCardiovascular Health and Risk FactorsPhytochemicals and Antioxidant Activities

The DOI matches its Crossref record; 47 of the 49 references it cites were found in a registry or an index.

Increased consumption of fruit and vegetables is related to a reduced risk of coronary heart disease: meta-analysis of cohort studies

He, F J, Nowson, C A, Lucas, M, MacGregor, G A·2007·Journal of Human Hypertension

Open this paper in CoChat — free account

Abstract

Increased consumption of fruit and vegetables has been shown to be associated with a reduced risk of coronary heart disease (CHD) in many epidemiological studies, however, the extent of the association is uncertain. We quantitatively assessed the relation between fruit and vegetable intake and incidence of CHD by carrying out a meta-analysis of cohort studies. Studies were included if they reported relative risks (RRs) and corresponding 95% confidence interval (CI) of CHD with respect to frequency of fruit and vegetable intake. Twelve studies, consisting of 13 independent cohorts, met the inclusion criteria. There were 278,459 individuals (9143 CHD events) with a median follow-up of 11 years. Compared with individuals who had less than 3 servings/day of fruit and vegetables, the pooled RR of CHD was 0.93 (95% CI: 0.86-1.00, P=0.06) for those with 3-5 servings/day and 0.83 (0.77-0.89, P<0.0001) for those with more than 5 servings/day. Subgroup analyses showed that both fruits and vegetables had a significant protective effect on CHD. Our meta-analysis of prospective cohort studies demonstrates that increased consumption of fruit and vegetables from less than 3 to more than 5 servings/day is related to a 17% reduction in CHD risk, whereas increased intake to 3-5 servings/day is associated with a smaller and borderline significant reduction in CHD risk. These results provide strong support for the recommendations to consume more than 5 servings/day of fruit and vegetables.

Integrity signals

Registry

Crossref · 10.1038/sj.jhh.1002212

Cites

47 of 47 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Yusuf, S., Hawken, S., Ôunpuu, S., Dans, T., Avezum, A., Lanas, F., McQueen, M., Budaj, A., Pais, P., Varigos, J., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17018-9 · Cited by 12,026
A Clinical Trial of the Effects of Dietary Patterns on Blood Pressure
Appel, L. J., Moore, T. J., Obarzanek, E., Vollmer, W. M., Svetkey, L. P., Sacks, F. M., Bray, G. A., Vogt, T. M., Cutler, J. A., Windhauser, M. M., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704173361601 · Cited by 5,981
Diet, nutrition and the prevention of chronic diseases : report of a Joint WHO/FAO Expert Consultation
Swinburn, B., Baba, N. H., Belhadj, M., Deurenberg‐Yap, M., Djazayery, A., Forrester, T., Galuska, D. A., Herman, S. T., James, W. P. T., Kabangu, J. R. M., et al. (2003) · World Health Organization eBooks · Cited by 3,453
Mediterranean Diet, Traditional Risk Factors, and the Rate of Cardiovascular Complications After Myocardial Infarction: Final Report of the Lyon Diet Heart Study
de Lorgeril, M., Salen, P., Martin, J.-L., Monjaud, I., Delaye, J., & Mamelle, N. (1999) · Circulation · doi:10.1161/01.cir.99.6.779 · Cited by 2,910
Diabetes and Cardiovascular Disease: A Statement for Healthcare Professionals From the American Heart Association
Grundy, S. M., Benjamin, I. J., Burke, G. L., Chait, A., Eckel, R. H., Howard, B. V., Mitch, W., Smith, S. C., & Sowers, J. R. (1999) · Circulation · doi:10.1161/01.cir.100.10.1134 · Cited by 2,698
Investigating and dealing with publication and other biases in meta-analysis
Sterne, J. A. C., Egger, M., & Smith, G. D. (2001) · BMJ · doi:10.1136/bmj.323.7304.101 · Cited by 2,225
Homocysteine and Risk of Ischemic Heart Disease and Stroke: A Meta-analysis
Homocysteine Studies Collaboration (2002) · JAMA · doi:10.1001/jama.288.16.2015 · Cited by 2,059
Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
Wald, D. S., Law, M., & Morris, J. K. (2002) · BMJ · doi:10.1136/bmj.325.7374.1202 · Cited by 1,945

Show all 49 references

Research works printed but not linked: 1

Report of the Cardiovascular Review Group Committee on Medical Aspects of Food Policy. Nutritional Aspects of Cardiovascular Disease. 1994. London: HMSO.

Sorted by citations

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Lim, S. S., Vos, T., Flaxman, A. D., Danaei, G., Shibuya, K., Adair-Rohani, H., AlMazroa, M. A., Amann, M., Anderson, H. R., Andrews, K. G., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61766-8 · Cited by 11,805
Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases
Del Rio, D., Rodriguez-Mateos, A., Spencer, J. P. E., Tognolini, M., Borges, G., & Crozier, A. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4581 · Cited by 2,601
Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality - a systematic review and dose-response meta-analysis of prospective studies
Aune, D., Giovannucci, E., Boffetta, P., Fadnes, L. T., Keum, N., Norat, T., Greenwood, D. C., Riboli, E., Vatten, L. J., & Tonstad, S. (2017) · International Journal of Epidemiology · doi:10.1093/ije/dyw319 · Cited by 2,419
Alternative Dietary Indices Both Strongly Predict Risk of Chronic Disease
Chiuve, S. E., Fung, T. T., Rimm, E. B., Hu, F. B., McCullough, M. L., Wang, M., Stampfer, M. J., & Willett, W. C. (2012) · The Journal of Nutrition · doi:10.3945/jn.111.157222 · Cited by 1,951
Critical review: vegetables and fruit in the prevention of chronic diseases
Boeing, H., Bechthold, A., Bub, A., Ellinger, S., Haller, D., Kroke, A., Leschik‐Bonnet, E., Müller, M. J., Oberritter, H., Schulze, M. B., et al. (2012) · European Journal of Nutrition · doi:10.1007/s00394-012-0380-y · Cited by 1,875
Marital quality and health: A meta-analytic review.
Robles, T. F., Slatcher, R. B., Trombello, J. M., & McGinn, M. M. (2013) · Psychological Bulletin · doi:10.1037/a0031859 · Cited by 1,764
American Cancer Society guidelines on nutrition and physical activity for cancer prevention
Kushi, L. H., Doyle, C., McCullough, M. L., Rock, C. L., Demark‐Wahnefried, W., Bandera, E. V., Gapstur, S. M., Patel, A. V., Andrews, K. S., & Gansler, T. S. (2012) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.20140 · Cited by 1,399
Determinants of fruit and vegetable consumption among children and adolescents: a review of the literature. Part I: Quantitative studies.
Rasmussen, M., Krølner, R. F., Klepp, K., Lytle, L., Brug, J., Bere, E. T., & Due, P. (2006) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-3-22 · Cited by 1,096
The Mediterranean Diet, its Components, and Cardiovascular Disease
Widmer, R. J., Flammer, A. J., Lerman, L. O., & Lerman, A. (2015) · The American Journal of Medicine · doi:10.1016/j.amjmed.2014.10.014 · Cited by 963
“Another large (over 200,000 patients) meta-analysis of observational studies showed a 17% reduction in cardiovascular disease events with three to five servings of fruits and vegetables daily as the primary endpoint (60), data that were reaffirmed two years later (61).”
Background
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors
Quach, A., Levine, M. E., Tanaka, T., Lu, A. T., Chen, B. H., Ferrucci, L., Ritz, B., Bandinelli, S., Neuhouser, M. L., Beasley, J. M., et al. (2017) · Aging · doi:10.18632/aging.101168 · Cited by 801
American Cancer Society guideline for diet and physical activity for cancer prevention
Rock, C. L., Thomson, C., Gansler, T., Gapstur, S. M., McCullough, M. L., Patel, A. V., Andrews, K. S., Bandera, E. V., Spees, C. K., Robien, K., et al. (2020) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21591 · Cited by 789
Australian Dietary Guidelines
Curriculum, K. (2006) · Cited by 768
Total phenolic compounds and antioxidant capacities of major fruits from Ecuador
Vasco, C., Ruales, J., & Kamal‐Eldin, A. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2008.04.054 · Cited by 728
Food groups and risk of coronary heart disease, stroke and heart failure: A systematic review and dose-response meta-analysis of prospective studies
Bechthold, A., Boeing, H., Schwedhelm, C., Hoffmann, G., Knüppel, S., Iqbal, K., De Henauw, S., Michels, N., Devleesschauwer, B., Schlesinger, S., et al. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1392288 · Cited by 693
“For vegetables and fruits, our results are similar to previous meta-analyses that revealed an inverse association between intake and CHD (Gan et al. 2015; Mente et al. 2009) (Dauchet et al. 2006; He et al. 2007), and stroke risk (Aune et al. 2017; He et al. 2006; Hu et al. 2014).”
Fruit Development and Ripening
Seymour, G. B., Østergaard, L., Chapman, N. H., Knapp, S., & Martin, C. R. (2013) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050312-120057 · Cited by 684
Fruits, vegetables, and health: A comprehensive narrative, umbrella review of the science and recommendations for enhanced public policy to improve intake
Wallace, T. C., Bailey, R. L., Blumberg, J. B., Burton-Freeman, B., Chen, C.-Y. O., Crowe-White, K. M., Drewnowski, A., Hooshmand, S., Johnson, E., Lewis, R., et al. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1632258 · Cited by 638
Exploitation of vegetables and fruits through lactic acid fermentation.
Di Cagno, R., Coda, R., De Angelis, M., & Gobbetti, M. (2013) · Food Microbiology · doi:10.1016/j.fm.2012.09.003 · Cited by 644
Etiologic effects and optimal intakes of foods and nutrients for risk of cardiovascular diseases and diabetes: Systematic reviews and meta-analyses from the Nutrition and Chronic Diseases Expert Group (NutriCoDE)
Micha, R., Shulkin, M., Peñalvo, J. L., Khatibzadeh, S., Singh, G. M., Rao, M., Fahimi, S., Powles, J. W., & Mozaffarian, D. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175149 · Cited by 507
Global, regional and national consumption of major food groups in 1990 and 2010: a systematic analysis including 266 country-specific nutrition surveys worldwide
Micha, R., Khatibzadeh, S., Shi, P., Andrews, K. G., Engell, R. E., & Mozaffarian, D. (2015) · BMJ Open · doi:10.1136/bmjopen-2015-008705 · Cited by 473
Antioxidant capacity, phenolic content and vitamin C in pulp, peel and seed from 24 exotic fruits from Colombia
Contreras‐Calderón, J., CALDERÓN-JAIMES, L. S., Guerra-Hernández, E. J., & García‐Villanova, B. (2010) · Food Research International · doi:10.1016/j.foodres.2010.11.003 · Cited by 467
Fruit and vegetable consumption and all-cause, cancer and CVD mortality: analysis of Health Survey for England data
Oyebode, O., Gordon-Dseagu, V., Walker, A., & Mindell, J. S. (2014) · Journal of Epidemiology and Community Health · doi:10.1136/jech-2013-203500 · Cited by 437
Influence of Individual and Combined Health Behaviors on Total and Cause-Specific Mortality in Men and Women
Kvaavik, E. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.76 · Cited by 423
Guidelines for Preventive Activities in General Practice
Ackermann, E. W., Harris, M., Alexander, K. L., Arcus, M., Bailey, L., Bennett, J. W., Mar, C. D., Emery, J. D., Ewald, B. D., Ewald, D. P., et al. (2012) · e-publications@bond (Bond University) · Cited by 421
The 2015 Dutch food-based dietary guidelines
Kromhout, D., Spaaij, C. J. K., de Goede, J., & Weggemans, R. M. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.52 · Cited by 416
Breast cancer survivorship: a comprehensive review of long-term medical issues and lifestyle recommendations
Bodai, B. I., & Tuso, P. (2015) · The Permanente Journal · doi:10.7812/tpp/14-241 · Cited by 397
Do ketogenic diets really suppress appetite? A systematic review and meta‐analysis
Gibson, A. A., Seimon, R. V., Lee, C. M. Y., Ayre, J., Franklin, J., Markovic, T. P., Caterson, I. D., & Sainsbury, A. (2015) · Obesity Reviews · doi:10.1111/obr.12230 · Cited by 366
Determinants of fruit and vegetable consumption among children and adolescents: a review of the literature. Part II: qualitative studies
Krølner, R. F., Rasmussen, M., Brug, J., Klepp, K., Wind, M., & Due, P. (2011) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-8-112 · Cited by 372
In Vitro Models for Studying Secondary Plant Metabolite Digestion and Bioaccessibility
Alminger, M., Aura, A., Bohn, T., Dufour, C., El, S. N., Gomes, A., Karakaya, S., Martínez‐Cuesta, M. C., McDougall, G. J., Requena, T., et al. (2014) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12081 · Cited by 369
Beneficial effects of potassium on human health
He, F. J., & MacGregor, G. A. (2008) · Physiologia Plantarum · doi:10.1111/j.1399-3054.2007.01033.x · Cited by 352
Self-citation
Contributions of risk factors and medical care to cardiovascular mortality trends
Ezzati, M., Obermeyer, Z., Tzoulaki, I., Mayosi, B. M., Elliott, P., & Leon, D. A. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.82 · Cited by 338
Antioxidant capacities and total phenolic contents of 56 vegetables
Deng, G.-F., Lin, X., Xu, X., Gao, L., Xie, J.-F., & Li, H.-B. (2012) · Journal of Functional Foods · doi:10.1016/j.jff.2012.10.015 · Cited by 331
A review of the impact of preparation and cooking on the nutritional quality of vegetables and legumes
Fabbri, A. D. T., & Crosby, G. A. (2015) · International Journal of Gastronomy and Food Science · doi:10.1016/j.ijgfs.2015.11.001 · Cited by 326
Applying the Socio-ecological Model to Improving Fruit and Vegetable Intake Among Low-Income African Americans
Robinson, T. D. (2008) · Journal of Community Health · doi:10.1007/s10900-008-9109-5 · Cited by 361
Cherry Antioxidants: From Farm to Table
Ferretti, G., Bacchetti, T., Belleggia, A., & Neri, D. (2010) · Molecules · doi:10.3390/molecules15106993 · Cited by 326
Vegetarian diets, low-meat diets and health: a review
McEvoy, C. T., Temple, N., & Woodside, J. V. (2012) · Public Health Nutrition · doi:10.1017/s1368980012000936 · Cited by 316
Dietary Fruits and Vegetables and Cardiovascular Diseases Risk
Alissa, E. M., & Ferns, G. A. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1040487 · Cited by 322
Review of dried fruits: Phytochemicals, antioxidant efficacies, and health benefits
Chang, S. K., Alasalvar, C., & Shahidi, F. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.11.034 · Cited by 292
Dietary Intake of Carotenoids and Their Antioxidant and Anti-Inflammatory Effects in Cardiovascular Care
Ciccone, M. M., Cortese, F., Gesualdo, M., Carbonara, S., Zito, A., Ricci, G., Pascalis, F. D., Scicchitano, P., & Riccioni, G. (2013) · Mediators of Inflammation · doi:10.1155/2013/782137 · Cited by 298
Fresh Fruit consumption and major cardiovascular disease in China
Du, H., Li, L., Bennett, D., Guo, Y., Key, T. J., Bian, Z., Sherliker, P., Gao, H., Chen, Y., Yang, L., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1501451 · Cited by 281
Fruit Polyphenols: A Review of Anti-inflammatory Effects in Humans
Joseph, S. V., Edirisinghe, I., & Burton‐Freeman, B. M. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2013.767221 · Cited by 296
Personal financial incentives for changing habitual health-related behaviors: A systematic review and meta-analysis
Mantzari, E., Vogt, F., Shemilt, I., Wei, Y., Higgins, J. P. T., & Marteau, T. M. (2015) · Preventive Medicine · doi:10.1016/j.ypmed.2015.03.001 · Cited by 289
Potential of Fruit Wastes as Natural Resources of Bioactive Compounds
Deng, G., Shen, C., Xu, X., Kuang, R.-D., Guo, Y., Zeng, L.-S., Gao, L., Lin, X., Xie, J.-F., Xia, E.-Q., et al. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms13078308 · Cited by 271
Changes in diet through adolescence and early adulthood: longitudinal trajectories and association with key life transitions
Winpenny, E. M., van Sluijs, E. M. F., White, M. J., Klepp, K., Wold, B., & Lien, N. (2018) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-018-0719-8 · Cited by 293
Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study
Crowe, F. L., Roddam, A. W., Key, T. J., Appleby, P. N., Overvad, K., Jakobsen, M. U., Tjonneland, A., Hansen, L., Boeing, H., Weikert, C., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehq465 · Cited by 263
Fruits, vegetables and coronary heart disease
Dauchet, L., Amouyel, P., & Dallongeville, J. (2009) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2009.131 · Cited by 270
Nonlinear Reduction in Risk for Colorectal Cancer by Fruit and Vegetable Intake Based on Meta-analysis of Prospective Studies
Aune, D., Lau, R., Chan, D. S. M., Vieira, R., Greenwood, D. C., Kampman, E., & Norat, T. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.04.013 · Cited by 278
Lifestyle and nutritional imbalances associated with Western diseases: causes and consequences of chronic systemic low-grade inflammation in an evolutionary context
Ruiz-Núñez, B., Pruimboom, L., Dijck-Brouwer, D. A. J., & Muskiet, F. A. J. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.02.009 · Cited by 246
Changes in dietary habits after migration and consequences for health: a focus on South Asians in Europe
Holmboe‐Ottesen, G., & Wandel, M. (2012) · Food & Nutrition Research · doi:10.3402/fnr.v56i0.18891 · Cited by 274
Berries: Anti-inflammatory Effects in Humans
Joseph, S. V., Edirisinghe, I., & Burton‐Freeman, B. M. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf4044056 · Cited by 249
Fruit and vegetable consumption and health outcomes: an umbrella review of observational studies
Angelino, D., Godos, J., Ghelfi, F., Tieri, M., Titta, L., Lafranconi, A., Marventano, S., Alonzo, E., Gambera, A., Sciacca, S., et al. (2019) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2019.1571021 · Cited by 247
Worldwide Exposures to Cardiovascular Risk Factors and Associated Health Effects
Tzoulaki, I., Elliott, P., Kontis, V., & Ezzati, M. (2016) · Circulation · doi:10.1161/circulationaha.115.008718 · Cited by 245
Citrus Flavanones: What Is Their Role in Cardiovascular Protection?
Chanet, A., Milenković, D., Manach, C., Mazur, A., & Morand, C. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf300669s · Cited by 233
Guidelines for the New Nordic Diet
Mithril, C. E., Dragsted, L. O., Meyer, C., Blauert, E., Holt, M. K., & Astrup, A. V. (2012) · Public Health Nutrition · doi:10.1017/s136898001100351x · Cited by 236
Global Vegetable Intake and Supply Compared to Recommendations: A Systematic Review
Kalmpourtzidou, A., Eilander, A., & Talsma, E. F. (2020) · Nutrients · doi:10.3390/nu12061558 · Cited by 233
Antioxidant capacity and related parameters of different fruit formulations
Müller, L., Gnoyke, S., Popken, A. M., & Böhm, V. (2010) · LWT · doi:10.1016/j.lwt.2010.02.004 · Cited by 229
Vitamin C and Heart Health: A Review Based on Findings from Epidemiologic Studies
Moser, M., & Chun, O. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17081328 · Cited by 222
Effects of grape antioxidant dietary fiber in cardiovascular disease risk factors
Pérez‐Jiménez, J., Serrano, J. C. E., Tabernero, M., Arranz, S., Diaz-Rubio, M. E., García‐Diz, L., Goñi, I., & Saura-Calixto, F. D. (2008) · Nutrition · doi:10.1016/j.nut.2008.03.012 · Cited by 230
Coronary heart disease prevention: Nutrients, foods, and dietary patterns
Bhupathiraju, S. N., & Tucker, K. L. (2011) · Clinica Chimica Acta · doi:10.1016/j.cca.2011.04.038 · Cited by 231
The southern rural health and mortality penalty: A review of regional health inequities in the United States
Miller, C. E., & Vasan, R. S. (2020) · Social Science & Medicine · doi:10.1016/j.socscimed.2020.113443 · Cited by 234
Associations between food and beverage groups and major diet-related chronic diseases: an exhaustive review of pooled/meta-analyses and systematic reviews
Fardet, A., & Boirie‌, Y. (2014) · Nutrition Reviews · doi:10.1111/nure.12153 · Cited by 216
Fruit and vegetable consumption and risk of cardiovascular disease: A meta-analysis of prospective cohort studies
Zhan, J., Liu, Y.-J., Cai, L.-B., Xu, F.-R., Xie, T., & He, Q.-Q. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1008980 · Cited by 217
Financial incentives increase fruit and vegetable intake among Supplemental Nutrition Assistance Program participants: a randomized controlled trial of the USDA Healthy Incentives Pilot
Olsho, L. E. W., Klerman, J. A., Wilde, P., & Bartlett, S. (2016) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.129320 · Cited by 218
Urban agriculture: a global analysis of the space constraint to meet urban vegetable demand
Martellozzo, F., Landry, J., Plouffe, D., Seufert, V., Rowhani, P., & Ramankutty, N. (2014) · Environmental Research Letters · doi:10.1088/1748-9326/9/6/064025 · Cited by 213
Plant Foods, Antioxidant Biomarkers, and the Risk of Cardiovascular Disease, Cancer, and Mortality: A Review of the Evidence
Aune, D. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz042 · Cited by 222
Functional Foods and Nutraceuticals in the Primary Prevention of Cardiovascular Diseases
Alissa, E. M., & Ferns, G. A. (2012) · Journal of Nutrition and Metabolism · doi:10.1155/2012/569486 · Cited by 221
Flavanols and cardiovascular disease prevention
Heiß, C., Keen, C. L., & Kelm, M. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq332 · Cited by 202
Berry (Poly)phenols and Cardiovascular Health
Rodriguez‐Mateos, A., Heiß, C., Borges, G., & Crozier, A. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf403757g · Cited by 195
Food Consumption Patterns of Infants and Toddlers: Findings from the Feeding Infants and Toddlers Study (FITS) 2016
Roess, A., Jacquier, E. F., Catellier, D., Carvalho, R. S., Lutes, A. C., Anater, A. S., & Dietz, W. H. (2018) · Journal of Nutrition · doi:10.1093/jn/nxy171 · Cited by 204
Relation of Different Fruit and Vegetable Sources With Incident Cardiovascular Outcomes: A Systematic Review and Meta‐Analysis of Prospective Cohort Studies
Zurbau, A., Au‐Yeung, F., Mejía, S. B., Khan, T. A., Vuksan, V. V. V., Jovanovski, E., Leiter, L. A., Kendall, C. W. C., Jenkins, D. J. A., & Sievenpiper, J. L. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.017728 · Cited by 204
Red and processed meat consumption and risk of stroke: a meta-analysis of prospective cohort studies
Chen, G.-C., Lv, D.-B., Pang, Z., & Liu, Q.-F. (2013) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2012.180 · Cited by 184
Insufficient Fruit and Vegetable Intake in a Low- and Middle-Income Setting: A Population-Based Survey in Semi-Urban Tanzania
Msambichaka, B., Eze, I. C., Abdul, R., Abdulla, S., Klatser, P. R., Tanner, M., Kaushik, R., Geubbels, E. L. P. E., & Probst-Hensch, N. M. (2018) · Nutrients · doi:10.3390/nu10020222 · Cited by 186
Lycopene and tomato and risk of cardiovascular diseases: A systematic review and meta-analysis of epidemiological evidence
Cheng, H. M., Koutsidis, G., Lodge, J. K., Ashor, A. W., Siervo, M., & Lara, J. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1362630 · Cited by 192
Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease
Testai, L., & Calderone, V. (2017) · Nutrients · doi:10.3390/nu9050502 · Cited by 179
Dietary patterns and CVD: a systematic review and meta-analysis of observational studies
Rodríguez‐Monforte, M., Flores‐Mateo, G., & Sánchez, E. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515003177 · Cited by 181
Consumption of fruit and vegetable and risk of coronary heart disease: A meta-analysis of prospective cohort studies
Gan, Y., Tong, X., Li, L., Cao, S., Yin, X., Gao, C., Herath, C., Li, W., Jin, Z., Chen, Y., et al. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.01.077 · Cited by 173
Quantity and variety in fruit and vegetable intake and risk of coronary heart disease
Bhupathiraju, S. N., Wedick, N. M., Pan, A., Manson, J. E., Rexrode, K. M., Willett, W. C., Rimm, E. B., & Hu, F. B. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.066381 · Cited by 175
Fruit and vegetable consumption trends among adolescents from 2002 to 2010 in 33 countries
Vereecken, C. A., Pedersen, T. P., Ojala, K., Krølner, R. F., Dzielska, A., Ahluwalia, N., Giacchi, M. V., & Kelly, C. N. M. (2015) · European Journal of Public Health · doi:10.1093/eurpub/ckv012 · Cited by 170
Fruit, vegetables, and olive oil and risk of coronary heart disease in Italian women: the EPICOR Study
Bendinelli, B., Masala, G., Saieva, C., Salvini, S., Calonico, C., Sacerdote, C., Agnoli, C., Grioni, S., Frasca, G., Mattiello, A., et al. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.000521 · Cited by 172
Dietary fiber intake in relation to coronary heart disease and all-cause mortality over 40 y: the Zutphen Study
Streppel, M. T., Ocké, M. C., Boshuizen, H. C., Kok, F. J., & Kromhout, D. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.4.1119 · Cited by 170
State-specific trends in fruit and vegetable consumption among adults - United States, 2000-2009.
Grimm, K. A., Blanck, H. M., Scanlon, K. S., Moore, L. V., Grummer-Strawn, L. M., & Foltz, J. L. (2010) · MMWR Morbidity and Mortality Weekly Report · Cited by 170
Effect of sorghum flour addition on resistant starch content, phenolic profile and antioxidant capacity of durum wheat pasta
Khan, I., Yousif, A. M., Johnson, S. K., & Gamlath, S. (2013) · Food Research International · doi:10.1016/j.foodres.2013.07.059 · Cited by 166
Effects of Potassium Chloride and Potassium Bicarbonate on Endothelial Function, Cardiovascular Risk Factors, and Bone Turnover in Mild Hypertensives
He, F. J., Marciniak, M., Carney, C., Markandu, N. D., Anand, V., Fraser, W. D., Dalton, R. N., Kaski, J. C., & MacGregor, G. A. (2010) · Hypertension · doi:10.1161/hypertensionaha.109.147488 · Cited by 164
Self-citation
Effect of lactic acid fermentation on antioxidant, texture, color and sensory properties of red and green smoothies
Cagno, R. D., Minervini, G., Rizzello, C. G., Angelis, M. D., & Gobbetti, M. (2011) · Food Microbiology · doi:10.1016/j.fm.2011.02.011 · Cited by 164
Authors' Perspective: What is the Optimum Intake of Vitamin C in Humans?
Frei, B. B., Birlouez‐Aragon, I., & Lykkesfeldt, J. (2012) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2011.649149 · Cited by 173
Health effects of adopting low greenhouse gas emission diets in the UK
Milner, J., Green, R., Dangour, A. D., Haines, A., Chalabi, Z., Spadaro, J. V., Markandya, A., & Wilkinson, P. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-007364 · Cited by 163
Fruit and Vegetable Intake During Infancy and Early Childhood
Grimm, K. A., Kim, S. A., Yaroch, A. L., & Scanlon, K. S. (2014) · PEDIATRICS · doi:10.1542/peds.2014-0646k · Cited by 152
Dietary polyphenols regulate endothelial function and prevent cardiovascular disease
Yamagata, K., Tagami, M., & Yamori, Y. (2014) · Nutrition · doi:10.1016/j.nut.2014.04.011 · Cited by 156
The Associations of Fruit and Vegetable Intakes with Burden of Diseases: A Systematic Review of Meta-Analyses
Yip, C. S. C., Chan, W. F. M., & Fielding, R. (2019) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2018.11.007 · Cited by 162
Dietary composition and nutrient content of the New Nordic Diet
Mithril, C. E., Dragsted, L. O., Meyer, C., Tetens, I., Biltoft-Jensen, A. P., & Astrup, A. V. (2012) · Public Health Nutrition · doi:10.1017/s1368980012004521 · Cited by 149
Human health risk assessment on the consumption of fruits and vegetables containing residual pesticides: A cancer and non-cancer risk/benefit perspective
Valcke, M., Bourgault, M.-H., Rochette, L., Normandin, L., Samuel, O., Belleville, D., Blanchet, C., & Phaneuf, D. (2017) · Environment International · doi:10.1016/j.envint.2017.07.023 · Cited by 146
Mechanisms Underlying Biological Effects of Cruciferous Glucosinolate-Derived Isothiocyanates/Indoles: A Focus on Metabolic Syndrome
Esteve, M. (2020) · Frontiers in Nutrition · doi:10.3389/fnut.2020.00111 · Cited by 147
Increased Consumption of Fruit and Vegetables Is Related to a Reduced Risk of Cognitive Impairment and Dementia: Meta-Analysis
Jiang, X., Huang, J., Song, D., Deng, R., Wei, J., & Zhang, Z. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00018 · Cited by 147
The Contribution of Fruit and Vegetable Consumption to Human Health
Yahia, E. M. (2009) · Wiley eBooks · doi:10.1002/9780813809397.ch1 · Cited by 136
The influence of socio-demographic, psychological and knowledge-related variables alongside perceived cooking and food skills abilities in the prediction of diet quality in adults: a nationally representative cross-sectional study
McGowan, L. J., Pot, G. K., Stephen, A. M., Lavelle, F., Spence, M., Raats, M. M., Hollywood, L. E., McDowell, D., McCloat, A., Mooney, E., et al. (2016) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-016-0440-4 · Cited by 148
Fruit and vegetable consumption in a sample of 11-year-old children in ten European countries – the PRO GREENS cross-sectional survey
Lynch, C., Kristjansdottir, Á. G., Velde, S. J. T., Lien, N., Roos, E., Þórsdóttir, I., Krawinkel, M. B., de Almeida, M. D. V., Papadaki, A., Ribič, C. H., et al. (2014) · Public Health Nutrition · doi:10.1017/s1368980014001347 · Cited by 134
Characterisation of Mediterranean Grape Pomace Seed and Skin Extracts: Polyphenolic Content and Antioxidant Activity
Ky, I., & Teissèdre, P. (2015) · Molecules · doi:10.3390/molecules20022190 · Cited by 132
The potential role of fruit and vegetables in aspects of psychological well-being: a review of the literature and future directions
Rooney, C., McKinley, M. C., & Woodside, J. V. (2013) · Proceedings of The Nutrition Society · doi:10.1017/s0029665113003388 · Cited by 130
Personalising nutritional guidance for more effective behaviour change
Celis-Morales, C., Lara, J., & Mathers, J. C. (2015) · Proceedings of the Nutrition Society · doi:10.1017/s0029665114001633 · Cited by 130
Significance of occlusal force for dietary fibre and vitamin intakes in independently living 70-year-old Japanese: from SONIC Study.
Inomata, C., Ikebe, K., Kagawa, R., Okubo, H., Sasaki, S., Okada, T., Takeshita, H., Tada, S., Matsuda, K., Kurushima, Y., et al. (2014) · E -journal of dentistry · doi:10.1016/j.jdent.2014.02.015 · Cited by 120
Consumption of fruit and vegetables and risk of frailty: a dose-response analysis of 3 prospective cohorts of community-dwelling older adults
García‐Esquinas, E., Rahi, B., Pérès, K., Colpo, M., Dartigues, J., Bandinelli, S., Féart, C., & Rodríguez‐Artalejo, F. (2016) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.125781 · Cited by 126

Authors: He, F. J., Nowson, C. A., Lucas, M., & MacGregor, G. A.
Affiliations: St George's, University of London (GB)
Deakin University (AU)
Corresponding author: He, F J
ORCID: He, F J
Nowson, C A
MacGregor, G A
Venue: Journal of Human Hypertension
Publisher: Springer Science and Business Media LLC
Published: 2007-04-19
Volume: 21
Issue: 9
Pages: 717-728
ISSN: 0950-9240 (ISSN-L)
1476-5527
DOI: 10.1038/sj.jhh.1002212
OpenAlex: W1999386633
Cited by: 741
References: 49
Citations by year: 2026: 5 · 2025: 15 · 2024: 19 · 2023: 23 · 2022: 30 · 2021: 38 · 2020: 44 · 2019: 44 · 2018: 41 · 2017: 52 · 2016: 56 · 2015: 83 · 2014: 65 · 2013: 64 · 2012: 56
FWCI: 3.72
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
www.springer.com/tdm (vor)
Locations: Journal of Human Hypertension (publishedVersion)
PubMed (publishedVersion)
Own your potential (DEAKIN) (submittedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Keywords: fruit and vegetable intake, coronary artery disease, dietary intake, cardiovascular risk reduction, dietary recommendations, prospective cohort
MeSH terms: Coronary Disease, Fruit, Humans, Vegetables, Cohort Studies, Risk Reduction Behavior

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Increased consumption of fruit and vegetables is related to a reduced risk of coronary heart disease: meta-analysis of cohort studies

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks