Cited by 217Nutritional Studies and DietCardiovascular Health and Risk FactorsPhytochemicals and Antioxidant Activities

Fruit and vegetable consumption and risk of cardiovascular disease: A meta-analysis of prospective cohort studies

Zhan, Jian, Liu, Yu-Jian, Cai, Long-Biao, Xu, Fang-Rong, Xie, Tao, He, Qi-Qiang·2017·Critical Reviews in Food Science and Nutrition

Abstract

A meta-analysis of prospective cohort studies was conducted to examine the relation between fruit and vegetables (FV) consumption and the risk of cardiovascular disease (CVD). We searched PubMed and EMBASE up to June 2014 for relevant studies. Pooled relative risks (RRs) were calculated and dose-response relationship was assessed. Thirty-eight studies, consisting of 47 independent cohorts, were eligible in this meta-analysis. There were 1,498,909 participants (44,013 CVD events) with a median follow-up of 10.5 years. The pooled RR (95% confidence interval) of CVD for the highest versus lowest category was 0.83 (0.79-0.86) for FV consumption, 0.84 (0.79-0.88) for fruit consumption, and 0.87 (0.83-0.91) for vegetable consumption, respectively. Dose-response analysis showed that those eating 800 g per day of FV consumption had the lowest risk of CVD. Our results indicate that increased FV intake is inversely associated with the risk of CVD. This meta-analysis provides strong support for the current recommendations to consume a high amount of FV to reduce CVD risk.

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Crossref · 10.1080/10408398.2015.1008980

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  • A recent meta-analysis showed that adults consuming 2.5 daily servings of fruit and vegetables (~200 g) had an 8% reduced risk of CVDs compared to adults who did not eat any fruit and vegetables over a 10.5-year follow-up.

    “In terms of relating fruit and vegetable intake to risk for cardiovascular disease, a recent meta-analysis showed that adults consuming five daily servings of fruit and vegetables (∼400 g) had a 15 % reduced risk of CVDs, while those consuming 2.5 daily servings (∼200 g) had a 8 % reduced risk of CVDs compared to adults who did not eat any fruit and vegetables over a 10.5-year follow-up period [78”
  • A recent meta-analysis showed that adults consuming five daily servings of fruit and vegetables (~400 g) had a 15% reduced risk of CVDs compared to adults who did not eat any fruit and vegetables over a 10.5-year follow-up.

    “In terms of relating fruit and vegetable intake to risk for cardiovascular disease, a recent meta-analysis showed that adults consuming five daily servings of fruit and vegetables (∼400 g) had a 15 % reduced risk of CVDs, while those consuming 2.5 daily servings (∼200 g) had a 8 % reduced risk of CVDs compared to adults who did not eat any fruit and vegetables over a 10.5-year follow-up period [78”

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Authors
Zhan, J., Liu, Y.-J., Cai, L.-B., Xu, F.-R., Xie, T., & He, Q.-Q.
Affiliations
Wuhan University (CN)
Corresponding author
He, Qi-Qiang
Venue
Critical Reviews in Food Science and Nutrition
Published
2015-06-26
Volume
57
Issue
8
Pages
1650-1663
ISSN
  • 1040-8398 (ISSN-L)
  • 1549-7852
OpenAlex
W2149818158
Cited by
217
References
64
Citations by year
2026: 6 · 2025: 17 · 2024: 19 · 2023: 19 · 2022: 26 · 2021: 25 · 2020: 28 · 2019: 37 · 2018: 21 · 2017: 13 · 2016: 5 · 2015: 1
FWCI
1.92
Type
journal article
Language
en
Open access
closed
Locations
  • Critical Reviews in Food Science and Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
Keywords
fruit and vegetable intake, cardiovascular risk, fruit consumption, vegetable consumption, dose-response relationship, dietary recommendations, prospective cohort
MeSH terms
Cardiovascular Diseases, Fruit, Humans, Risk Factors, Vegetables, Databases, Factual

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