Self-adhesive epidermal carbon nanotube electronics for tether-free long-term continuous recording of biosignals
Open accessAbstract
The long-term, continuous, inconspicuous, and noiseless monitoring of bioelectrical signals is critical to the early diagnosis of disease and monitoring health and wellbeing. However, it is a major challenge to record the bioelectrical signals of patients going about their daily lives because of the difficulties of integrating skin-like conducting materials, the measuring system, and medical technologies in a single platform. In this study, we developed a thin epidermis-like electronics that is capable of repeated self-adhesion onto skin, integration with commercial electronic components through soldering, and conformal contact without serious motion artifacts. Using well-mixed carbon nanotubes and adhesive polydimethylsiloxane, we fabricated an epidermal carbon nanotube electronics which maintains excellent conformal contact even within wrinkles in skin, and can be used to record electrocardiogram signals robustly. The electrode is biocompatible and can even be operated in water, which means patients can live normal lives despite wearing a complicated recording system.
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The CNT/aPDMS electrode patch was ultrathin (120 μm), extremely compliant (modulus of 27.5 kPa) and waterproof.
“the resulting electrode patch (Figure 3e) was ultrathin (120 µm), extremely compliant (modulus of 27.5 kPa) and waterproof.”
From Nanomaterial-Enabled Wearable Sensors for Healthcare (2018) · cites this paper as [95]
Nanomaterial-enabled dry electrodes have been demonstrated for wearable and long-term ECG sensing without irritating the skin.
“Nanomaterialenabled dry electrodes have been demonstrated for wearable and long-term ECG sensing without irritating the skin.[92,95,100]”
From Nanomaterial-Enabled Wearable Sensors for Healthcare (2018) · cites this paper as [95]
Only preliminary experiments were performed on biocompatibility of nanomaterials for wearable applications.
“For example, only preliminary experiments were performed on biocompatibility of nanomaterials for wearable applications.[94,95,205]”
From Nanomaterial-Enabled Wearable Sensors for Healthcare (2018) · cites this paper as [95]
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Cites
Kim, D.-H., Lu, N., Ma, R., Kim, Y.-S., Kim, R.-H., Wang, S., Wu, J., Won, S. M., Tao, H., Islam, A., et al. (2011) · Science · doi:10.1126/science.1206157 · Cited by 4,836 · see citing works
A stretchable carbon nanotube strain sensor for human-motion detection
Yamada, T., Hayamizu, Y., Yamamoto, Y., Yomogida, Y., Izadi-Najafabadi, A., Futaba, D. N., & Hata, K. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.36 · Cited by 3,247 · see citing works
Skin-like pressure and strain sensors based on transparent elastic films of carbon nanotubes
Lipomi, D. J., Vosgueritchian, M., Tee, B. C.-K., Hellstrom, S. L., Lee, J. A., Fox, C. H., & Bao, Z. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.184 · Cited by 3,188 · see citing works
Self-citationThermal conductivity of carbon nanotubes and their polymer nanocomposites: A review
Han, Z., & Fina, A. (2010) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2010.11.004 · Cited by 2,615 · see citing works
A wearable and highly sensitive pressure sensor with ultrathin gold nanowires
Gong, S., Schwalb, W., Wang, Y., Chen, Y., Tang, Y., Si, J., Shirinzadeh, B., & Cheng, W. (2014) · Nature Communications · doi:10.1038/ncomms4132 · Cited by 2,064 · see citing works
A Rubberlike Stretchable Active Matrix Using Elastic Conductors
Sekitani, T., Noguchi, Y., Hata, K., Fukushima, T., Aida, T., & Someya, T. (2008) · Science · doi:10.1126/science.1160309 · Cited by 1,369 · see citing works
Highly Conductive and Stretchable Silver Nanowire Conductors
Xu, F., & Zhu, Y. (2012) · Advanced Materials · doi:10.1002/adma.201201886 · Cited by 1,315 · see citing works
Ultrathin conformal devices for precise and continuous thermal characterization of human skin
Webb, R. C., Bonifas, A. P., Behnaz, A., Zhang, Y., Yu, K. J., Cheng, H., Shi, M., Bian, Z., Liu, Z., Kim, Y.-S., et al. (2013) · Nature Materials · doi:10.1038/nmat3755 · Cited by 1,229 · see citing works
Dry-Contact and Noncontact Biopotential Electrodes: Methodological Review
Chi, Y. M., Jung, T., & Cauwenberghs, G. (2010) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2010.2084078 · Cited by 1,068 · see citing works
Multifunctional Epidermal Electronics Printed Directly Onto the Skin
Yeo, W., Kim, Y., Lee, J., Ameen, A., Shi, L., Li, M., Wang, S., Ma, R., Jin, S. H., Kang, Z., et al. (2013) · Advanced Materials · doi:10.1002/adma.201204426 · Cited by 829 · see citing works
Self-citationMaterials and Optimized Designs for Human‐Machine Interfaces Via Epidermal Electronics
Jeong, J., Yeo, W., Akhtar, A., Norton, J. J. S., Kwack, Y., Li, S., Jung, S., Su, Y., Lee, W., Xia, J., et al. (2013) · Advanced Materials · doi:10.1002/adma.201301921 · Cited by 827 · see citing works
A direct comparison of wet, dry and insulating bioelectric recording electrodes
Searle, A., & Kirkup, L. (2000) · Physiological Measurement · doi:10.1088/0967-3334/21/2/307 · Cited by 726 · see citing works
CNT/PDMS Composite Flexible Dry Electrodesfor Long-Term ECG Monitoring
Jung, H.-C., Moon, J.-H., Baek, D.-H., Lee, J.-H., Choi, Y.-Y., Hong, J.-S., & Lee, S.-H. (2012) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2012.2190288 · Cited by 434 · see citing works
Self-citationA wireless wearable ECG sensor for long-term applications
Nemati, E., Deen, M., & Mondal, T. (2012) · IEEE Communications Magazine · doi:10.1109/mcom.2012.6122530 · Cited by 418 · see citing works
Characterizing and Patterning of PDMS‐Based Conducting Composites
Niu, X., Peng, S., Liu, L., Wen, W., & Sheng, P. (2007) · Advanced Materials · doi:10.1002/adma.200602515 · Cited by 415 · see citing works
Rational Design and Enhanced Biocompatibility of a Dry Adhesive Medical Skin Patch
Kwak, M. K., Jeong, H., & Suh, K. Y. (2011) · Advanced Materials · doi:10.1002/adma.201101694 · Cited by 341 · see citing works
Novel Dry Polymer Foam Electrodes for Long-Term EEG Measurement
Lin, C., Liao, L., Liu, Y., Wang, I.-J., Lin, B., & Chang, J.-Y. (2011) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2010.2102353 · Cited by 336 · see citing works
Zhang, Y., Xu, S. H., Fu, H., Lee, J., Su, J., Hwang, K., Rogers, J. A., & Huang, Y. Y. (2013) · Soft Matter · doi:10.1039/c3sm51360b · Cited by 311 · see citing works
Self-citationCapacitive Epidermal Electronics for Electrically Safe, Long‐Term Electrophysiological Measurements
Jeong, J., Kim, M. K., Cheng, H., Yeo, W., Huang, X., Liu, Y., Zhang, Y., Huang, Y., & Rogers, J. A. (2014) · Advanced Healthcare Materials · doi:10.1002/adhm.201300334 · Cited by 288 · see citing works
Novel dry electrodes for ECG monitoring
Gruetzmann, A., Hansen, S., & Müller, J. (2007) · Physiological Measurement · doi:10.1088/0967-3334/28/11/005 · Cited by 248 · see citing works
Electrical conductivity of pure carbon nanotube yarns
Miao, M. (2011) · Carbon · doi:10.1016/j.carbon.2011.05.008 · Cited by 244 · see citing works
ECG measurement on a chair without conductive contact
Lim, Y. G., Kim, K. K., & Park, S. (2006) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2006.872823 · Cited by 233 · see citing works
Solderable and electroplatable flexible electronic circuit on a porous stretchable elastomer
Jeong, G. S., Baek, D.-H., Jung, H., Song, J. H., Moon, J. H., Hong, S. W., Kim, I. Y., & Lee, S. (2012) · Nature Communications · doi:10.1038/ncomms1980 · Cited by 227 · see citing works
Self-citationMechanics of Epidermal Electronics
Wang, S., Li, M., Wu, J. C., Kim, D., Lu, N., Su, Y., Kang, Z., Huang, Y. Y., & Rogers, J. A. (2012) · Journal of Applied Mechanics · doi:10.1115/1.4005963 · Cited by 215 · see citing works
Hu, W., Niu, X., Li, L., Yun, S., Yu, Z., & Pei, Q. (2012) · Nanotechnology · doi:10.1088/0957-4484/23/34/344002 · Cited by 191 · see citing works
Nanofiber Web Textile Dry Electrodes for Long-Term Biopotential Recording
InOh, T., Yoon, S., Kim, T. E., Wi, H., Kim, K. J., Woo, E. J., & Sadleir, R. (2012) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2012.2201154 · Cited by 107 · see citing works
Bossuyt, F., Vervust, T., & Vanfleteren, J. (2013) · IEEE Transactions on Components Packaging and Manufacturing Technology · doi:10.1109/tcpmt.2012.2185792 · Cited by 92 · see citing works
Klode, J., Schöttler, L., Stoffels, I., Körber, A., Schadendorf, D., & Dissemond, J. (2011) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2010.03886.x · Cited by 73 · see citing works
Electrocardiography Pitfalls and Artifacts: The 10 Commandments
Baranchuk, A. M., Shaw, C., Alanazi, H., Campbell, D., Bally, K., Redfearn, D., Simpson, C. S., & Abdollah, H. (2009) · Critical Care Nurse · doi:10.4037/ccn2009607 · Cited by 60 · see citing works
Cumulative Irritation in Older and Younger Skin: a Comparison
Schwindt, D. A. (1998) · Acta Dermato Venereologica · doi:10.1080/000155598441864 · Cited by 58 · see citing works
Thin and flexible active electrodes with shield for capacitive electrocardiogram measurement
Lee, S. M., Sim, K. S., Kim, K. K., et al. (2010) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-010-0597-y · Cited by 57 · see citing works
Self-citationLee, S. M., Kim, J. H., Byeon, H. J., Choi, Y. Y., Park, K. S., & Lee, S. (2013) · Journal of Neural Engineering · doi:10.1088/1741-2560/10/3/036006 · Cited by 45 · see citing works
Self-citationDispersion of solvent-wet carbon nanotubes for electrical CNT/polydimethylsiloxane composite
Hong, J. S., Lee, J. H., & Nam, Y. (2013) · Carbon · doi:10.1016/j.carbon.2013.05.039 · Cited by 29 · see citing works
Self-citationSoldering-based easy packaging of thin polyimide multichannel electrodes for neuro-signal recording
Baek, D.-H., Han, C. H., Jung, H., et al. (2012) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/22/11/115017 · Cited by 8 · see citing works
Self-citation
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Cited by
Sorted by citations
Lab-on-Skin: A Review of Flexible and Stretchable Electronics for Wearable Health Monitoring
Liu, Y., Pharr, M., & Salvatore, G. A. (2017) · ACS Nano · doi:10.1021/acsnano.7b04898 · Cited by 1,725 · see citing works
Wearable sensors: modalities, challenges, and prospects
Heikenfeld, J., Jajack, A., Rogers, J., Gutruf, P., Tian, L., Pan, T., Li, R., Khine, M., Kim, J., Wang, J., et al. (2018) · Lab on a Chip · doi:10.1039/c7lc00914c · Cited by 1,434 · see citing works
Bio-Integrated Wearable Systems: A Comprehensive Review
Ray, T. R., Choi, J., Bandodkar, A. J., Krishnan, S., Gutruf, P., Tian, L., Ghaffari, R., & Rogers, J. A. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00573 · Cited by 1,350 · see citing works
Imani, S., Bandodkar, A. J., Mohan, A. M. V., Kumar, R., Yu, S., Wang, J., & Mercier, P. P. (2016) · Nature Communications · doi:10.1038/ncomms11650 · Cited by 861 · see citing works
Nanomaterial-Enabled Wearable Sensors for Healthcare
Yao, S., Swetha, P., & Zhu, Y. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700889 · Cited by 576 · see citing works
Zhang, L., Kumar, K. S., He, H., Cai, C. J., He, X., Gao, H., Yue, S., Li, C., Seet, R. C.-S., Ren, H., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18503-8 · Cited by 574 · see citing works
Wu, H., Yang, G., Zhu, K., Liu, S., Guo, W., Jiang, Z., & Li, Z. (2021) · Advanced Science · doi:10.1002/advs.202001938 · Cited by 395 · see citing works
Flexible Carbon Nanotube-Based Polymer Electrode for Long-Term Electrocardiographic Recording
Chi, M., Zhao, J., Dong, Y., & Wang, X. (2019) · Materials · doi:10.3390/ma12060971 · Cited by 68 · see citing works
Ambulatory cardiac bio-signals: From mirage to clinical reality through a decade of progress
Periyaswamy, T., & Balasubramanian, M. (2019) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2019.07.007 · Cited by 14 · see citing works
- Authors
- Lee, S. M., Byeon, H. J., Lee, J. H., Baek, D. H., Lee, K. H., Hong, J. S., & Lee, S.-H.
- Affiliations
- Korea University (KR)
- Kangwon National University (KR)
- Soongsil University (KR)
- Corresponding author
- Lee, Sang-Hoon
- Venue
- Scientific Reports
- Published
- 2014-08-15
- Volume
- 4
- Issue
- 1
- Pages
- 6074-6074
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC4133715
- OpenAlex
- W1970992788
- Cited by
- 181
- References
- 34
- Citations by year
- 2026: 6 · 2025: 13 · 2024: 16 · 2023: 18 · 2022: 16 · 2021: 19 · 2020: 19 · 2019: 28 · 2018: 14 · 2017: 20 · 2016: 8 · 2015: 4
- FWCI
- 5.53
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Scientific Reports (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Nanomaterials and Printing Technologies
- Keywords
- epidermal electronics, carbon nanotubes, self-adhesive electrodes, ECG monitoring, polydimethylsiloxane, motion artifacts, biocompatible electrodes, wearable health monitoring
- MeSH terms
- Adhesives, Biocompatible Materials, Electrocardiography, Equipment Design, Humans, Materials Testing, Microelectrodes, Biosensing Techniques, Monitoring, Ambulatory, Nanotubes, Carbon
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