Bioinspired polymer vesicles and membranes for biological and medical applications

Atom Transfer Radical Polymerization

Matyjaszewski, K., & Xia, J. (2001) · Chemical Reviews · doi:10.1021/cr940534g · Cited by 7,654

Stimuli-responsive nanocarriers for drug delivery

Mura, S., Nicolas, J., & Couvreur, P. (2013) · Nature Materials · doi:10.1038/nmat3776 · Cited by 6,289

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

Schafer, F. Q., & Buettner, G. R. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00480-4 · Cited by 4,587

New Polymer Synthesis by Nitroxide Mediated Living Radical Polymerizations

Hawker, C. J., Bosman, A. W., & Harth, E. (2001) · Chemical Reviews · doi:10.1021/cr990119u · Cited by 3,850

Liposome: classification, preparation, and applications

Akbarzadeh, A., Rezaei-Sadabady, R., Davaran, S., Joo, S. W., Zarghami, N., Hanifehpour, Y., Samiei, M., Kouhi, M., & Nejati-Koshki, K. (2013) · Nanoscale Research Letters · doi:10.1186/1556-276x-8-102 · Cited by 3,632

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

Fang, J., Nakamura, H., & Maeda, H. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.04.009 · Cited by 3,559

Polymersomes: Tough Vesicles Made from Diblock Copolymers

Discher, B. M., Won, Y.-Y., Ege, D. S., Lee, J. C.-M., Bates, F. S., Discher, D. E., & Hammer, D. A. (1999) · Science · doi:10.1126/science.284.5417.1143 · Cited by 2,512

Liposomes as nanomedical devices

Bozzuto, G., & Molinari, A. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s68861 · Cited by 2,261

Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications

Wicki, A., Witzigmann, D., Balasubramanian, V., & Huwyler, J. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.12.030 · Cited by 1,901

Biosensors: sense and sensibility

Turner, A. P. F. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35528d · Cited by 1,654

Recent Developments in Ring Opening Polymerization of Lactones for Biomedical Applications

Albertsson, A.-C., & Varma, I. K. (2003) · Biomacromolecules · doi:10.1021/bm034247a · Cited by 1,582

Living ring-opening metathesis polymerization

Bielawski, C. W., & Grubbs, R. H. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2006.08.006 · Cited by 1,518

Biomimetism and bioinspiration as tools for the design of innovative materials and systems

Sanchez, C., Arribart, H., & Giraud Guille, M. M. (2005) · Nature Materials · doi:10.1038/nmat1339 · Cited by 1,449

Vesicles and Liposomes: A Self‐Assembly Principle Beyond Lipids

Antonietti, M., & Förster, S. (2003) · Advanced Materials · doi:10.1002/adma.200300010 · Cited by 1,403

Radical addition–fragmentation chemistry in polymer synthesis

Moad, G., Rizzardo, E., & Thang, S. H. (2008) · Polymer · doi:10.1016/j.polymer.2007.11.020 · Cited by 1,397

Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery

Cheng, R., Meng, F., Deng, C., Klok, H.-A., & Zhong, Z. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.01.084 · Cited by 1,354

Polymer brushes via surface-initiated polymerizations

Edmondson, S., Osborne, V. L., & Huck, W. T. S. (2004) · Chemical Society Reviews · doi:10.1039/b210143m · Cited by 1,347

Overview of tag protein fusions: from molecular and biochemical fundamentals to commercial systems

Terpe, K. (2003) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-002-1158-6 · Cited by 1,342

Membrane proteins, lipids and detergents: not just a soap opera

Seddon, A. M., Curnow, P., & Booth, P. J. (2004) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2004.04.011 · Cited by 1,333

Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress

Lammers, T., Kiessling, F., Hennink, W. E., & Storm, G. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.09.063 · Cited by 1,324

Supramolecular Amphiphiles Based on Host–Guest Molecular Recognition Motifs

Yu, G., Jie, K., & Huang, F. (2015) · Chemical Reviews · doi:10.1021/cr5005315 · Cited by 1,025

Bacterial Small-Molecule Signaling Pathways

Camilli, A., & Bassler, B. L. (2006) · Science · doi:10.1126/science.1121357 · Cited by 977

Polymer-supported membranes as models of the cell surface

Tanaka, M., & Sackmann, E. (2005) · Nature · doi:10.1038/nature04164 · Cited by 915

Self-assembly and transformation of hybrid nano-objects and nanostructures under equilibrium and non-equilibrium conditions

Mann, S. (2009) · Nature Materials · doi:10.1038/nmat2496 · Cited by 867

Polymersomes

Discher, D. E., & Ahmed, F. (2006) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.8.061505.095838 · Cited by 844

Smart polymers: Physical forms and bioengineering applications

Kumar, A., Srivastava, A., Galaev, I. Y., & Mattiasson, B. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.003 · Cited by 742

Highly permeable polymeric membranes based on the incorporation of the functional water channel protein Aquaporin Z

Kumar, M., Grzelakowski, M., Zilles, J., Clark, M., & Meier, W. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708762104 · Cited by 716

Self-Assembled Monolayers and Polymer Brushes in Biotechnology: Current Applications and Future Perspectives

Senaratne, W., Andruzzi, L., & Ober, C. K. (2005) · Biomacromolecules · doi:10.1021/bm050180a · Cited by 695

Biodegradable Gold Nanovesicles with an Ultrastrong Plasmonic Coupling Effect for Photoacoustic Imaging and Photothermal Therapy

Huang, P., Lin, J., Li, W., Rong, P., Wang, Z., Wang, S., Wang, X., Sun, X., Aronova, M., Niu, G., et al. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201308986 · Cited by 672

Self-porating polymersomes of peg–pla and peg–pcl: Hydrolysis-triggered controlled release vesicles

Ahmed, F., & Discher, D. E. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.12.021 · Cited by 667

Photosensitizer-Loaded Gold Vesicles with Strong Plasmonic Coupling Effect for Imaging-Guided Photothermal/Photodynamic Therapy

Lin, J., Wang, S., Huang, P., Wang, Z., Chen, S., Niu, G., Li, W., He, J., Cui, D., Lu, G., et al. (2013) · ACS Nano · doi:10.1021/nn4011686 · Cited by 661

Polymeric Vesicles: From Drug Carriers to Nanoreactors and Artificial Organelles

Tanner, P., Baumann, P., Enea, R., Onaca, O., Palivan, C., & Meier, W. (2011) · Accounts of Chemical Research · doi:10.1021/ar200036k · Cited by 634

Surface-Initiated Polymer Brushes in the Biomedical Field: Applications in Membrane Science, Biosensing, Cell Culture, Regenerative Medicine and Antibacterial Coatings

Krishnamoorthy, M., Hakobyan, S., Ramstedt, M., & Gautrot, J. E. (2014) · Chemical Reviews · doi:10.1021/cr500252u · Cited by 604

Autonomous movement of platinum-loaded stomatocytes

Wilson, D. A., Nolte, R. J. M., & van Hest, J. C. M. (2012) · Nature Chemistry · doi:10.1038/nchem.1281 · Cited by 598

Phagocytosis and antigen presentation in dendritic cells

Savina, A., & Amigorena, S. (2007) · Immunological Reviews · doi:10.1111/j.1600-065x.2007.00552.x · Cited by 561

Cascade Reactions in Multicompartmentalized Polymersomes

Peters, R. J. R. W., Marguet, M., Marais, S., Fraaije, M. W., van Hest, J. C. M., & Lecommandoux, S. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201308141 · Cited by 561

Molecular Weight Dependence of Polymersome Membrane Structure, Elasticity, and Stability

Bermudez, H., Brannan, A. K., Hammer, D. A., Bates, F. S., & Discher, D. E. (2002) · Macromolecules · doi:10.1021/ma020669l · Cited by 547

Block copolymer vesicles—using concepts from polymer chemistry to mimic biomembranes

Kita-Tokarczyk, K., Grumelard, J., Haefele, T., & Meier, W. (2005) · Polymer · doi:10.1016/j.polymer.2005.02.083 · Cited by 517

The effects of polymeric nanostructure shape on drug delivery

Venkataraman, S., Hedrick, J. L., Ong, Z. Y., Yang, C., Ee, P. L. R., Hammond, P. T., & Yang, Y. Y. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.06.016 · Cited by 510

Multicompartmentalized polymeric systems: towards biomimetic cellular structure and function

Marguet, M., Bonduelle, C., & Lecommandoux, S. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35312a · Cited by 505

Reconstitution of Membrane Proteins into Liposomes

Rigaud, J., & Lévy, D. (2003) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(03)72004-7 · Cited by 501

Doxorubicin Loaded Magnetic Polymersomes: Theranostic Nanocarriers for MR Imaging and Magneto-Chemotherapy

Sanson, C., Diou, O., Thévenot, J., Ibarboure, E., Soum, A., Brûlet, A., Miraux, S., Thiaudière, E., Tan, S., Brisson, A., et al. (2011) · ACS Nano · doi:10.1021/nn102762f · Cited by 489

Temperature‐Controlled Assembly and Release from Polymer Vesicles of Poly(ethylene oxide)‐block‐ poly(N‐isopropylacrylamide)

Qin, S., Geng, Y., Discher, D. E., & Yang, S. (2006) · Advanced Materials · doi:10.1002/adma.200601019 · Cited by 478

Stimuli-Responsive Polymers and Their Applications in Nanomedicine

Cabane, E., Zhang, X., Langowska, K., Palivan, C. G., & Meier, W. (2012) · Biointerphases · doi:10.1007/s13758-011-0009-3 · Cited by 468

PEG-SS-PPS: Reduction-Sensitive Disulfide Block Copolymer Vesicles for Intracellular Drug Delivery

Cerritelli, S., Velluto, D., & Hubbell, J. A. (2007) · Biomacromolecules · doi:10.1021/bm070085x · Cited by 443

Nanotechnology in agro-food: From field to plate

Dasgupta, N., Ranjan, S., Mundekkad, D., Ramalingam, C., Shanker, R., & Kumar, A. (2015) · Food Research International · doi:10.1016/j.foodres.2015.01.005 · Cited by 437

How to exploit the full potential of the dip-coating process to better control film formation

Grosso, D. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm12837j · Cited by 400

A Biocompatible Oxidation-Triggered Carrier Polymer with Potential in Therapeutics

Broaders, K. E., Grandhe, S., & Fréchet, J. M. J. (2011) · Journal of the American Chemical Society · doi:10.1021/ja110468v · Cited by 392

Artificial Organelle: ATP Synthesis from Cellular Mimetic Polymersomes

Choi, H.-J., & Montemagno, C. D. (2005) · Nano Letters · doi:10.1021/nl051896e · Cited by 370

Modern physicochemical research on Langmuir monolayers

Dynarowicz-Łątka, P., Dhanabalan, A., & Oliveira, O. N. (2001) · Advances in Colloid and Interface Science · doi:10.1016/s0001-8686(99)00034-2 · Cited by 367

A Three‐Enzyme Cascade Reaction through Positional Assembly of Enzymes in a Polymersome Nanoreactor

van Dongen, S. F. M., Nallani, M., Cornelissen, J. J. L. M., Nolte, R. J. M., & van Hest, J. C. M. (2009) · Chemistry – A European Journal · doi:10.1002/chem.200802114 · Cited by 341

Semipermeable Polymer Vesicle (PICsome) Self-Assembled in Aqueous Medium from a Pair of Oppositely Charged Block Copolymers: Physiologically Stable Micro-/Nanocontainers of Water-Soluble Macromolecules

Koide, A., Kishimura, A., Osada, K., Jang, W.-D., Yamasaki, Y., & Kataoka, K. (2006) · Journal of the American Chemical Society · doi:10.1021/ja057993r · Cited by 327

Nanoreactors based on (polymerized) ABA-triblock copolymer vesicles

Nardin, C., Thoeni, S., Widmer, J., et al. (2000) · Chemical Communications · doi:10.1039/b004280n · Cited by 320

Magnetic field triggered drug release from polymersomes for cancer therapeutics

Oliveira, H., Pérez-Andrés, E., Thevenot, J., Sandre, O., Berra, E., & Lecommandoux, S. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.01.013 · Cited by 310

Anticancer nanomedicine and tumor vascular permeability; Where is the missing link?

Taurin, S., Nehoff, H., & Greish, K. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.07.013 · Cited by 309

Spotted vesicles, striped micelles and Janus assemblies induced by ligand binding

Christian, D. A., Tian, A., Ellenbroek, W. G., Levental, I., Rajagopal, K., Janmey, P. A., Liu, A. J., Baumgart, T., & Discher, D. E. (2009) · Nature Materials · doi:10.1038/nmat2512 · Cited by 306

A Dual-Responsive Supra-Amphiphilic Polypseudorotaxane Constructed from a Water-Soluble Pillar[7]arene and an Azobenzene-Containing Random Copolymer

Chi, X., Ji, X., Xia, D., & Huang, F. (2015) · Journal of the American Chemical Society · doi:10.1021/ja512978n · Cited by 296

Immobilization in Surface-Tethered Lipid Vesicles as a New Tool for Single Biomolecule Spectroscopy

Boukobza, E., Sonnenfeld, A., & Haran, G. (2001) · The Journal of Physical Chemistry B · doi:10.1021/jp012016x · Cited by 294

Synthetic Bio‐nanoreactor: Mechanical and Chemical Control of Polymersome Membrane Permeability

Gaitzsch, J., Appelhans, D., Wang, L., Battaglia, G., & Voit, B. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201108814 · Cited by 284

Multicompartment Polymersomes from Double Emulsions

Shum, H. C., Zhao, Y., Kim, S., & Weitz, D. A. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201006023 · Cited by 280

Reconstitution of Channel Proteins in (Polymerized) ABA Triblock Copolymer Membranes

Meier, W., Nardin, C., & Winterhalter, M. (2000) · Angewandte Chemie International Edition · doi:10.1002/1521-3773(20001215)39:24<4599::aid-anie4599>3.0.co;2-y · Cited by 274

Multiple Polymersomes for Programmed Release of Multiple Components

Kim, S.-H., Shum, H. C., Kim, J. W., Cho, J.-C., & Weitz, D. A. (2011) · Journal of the American Chemical Society · doi:10.1021/ja205687k · Cited by 250

Toward Intelligent Nanosize Bioreactors: A pH-Switchable, Channel-Equipped, Functional Polymer Nanocontainer

Broz, P., Driamov, S., Ziegler, J., Ben-Haim, N., Marsch, S., Meier, W., & Hunziker, P. (2006) · Nano Letters · doi:10.1021/nl0619305 · Cited by 248

Self-Immolative Polymersomes for High-Efficiency Triggered Release and Programmed Enzymatic Reactions

Liu, G., Wang, X., Hu, J., Zhang, G., & Liu, S. (2014) · Journal of the American Chemical Society · doi:10.1021/ja5030832 · Cited by 246

Recent trends in the tuning of polymersomes’ membrane properties

Le Meins, J. F., Sandre, O., & Lecommandoux, S. (2011) · The European Physical Journal E · doi:10.1140/epje/i2011-11014-y · Cited by 243

Amphiphilic block copolymer nanocontainers as bioreactors

Nardin, C., Widmer, J., Winterhalter, M., & Meier, W. (2001) · The European Physical Journal E · doi:10.1007/s101890170095 · Cited by 226

Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes

Scott, E. A., Stano, A., Gillard, M., Maio-Liu, A. C., Swartz, M. A., & Hubbell, J. A. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.04.060 · Cited by 221

Monosaccharide-Responsive Release of Insulin from Polymersomes of Polyboroxole Block Copolymers at Neutral pH

Kim, H., Kang, Y. J., Kang, S., & Kim, K. T. (2012) · Journal of the American Chemical Society · doi:10.1021/ja211728x · Cited by 219

Fluorescent labeling of tetracysteine-tagged proteins in intact cells

Hoffmann, C., Gaietta, G., Zürn, A., Adams, S. R., Terrillon, S., Ellisman, M. H., Tsien, R. Y., & Lohse, M. J. (2010) · Nature Protocols · doi:10.1038/nprot.2010.129 · Cited by 213

Multiresponsive, Hierarchically Structured Membranes: New, Challenging, Biomimetic Materials for Biosensors, Controlled Release, Biochemical Gates, and Nanoreactors

Tokarev, I., & Minko, S. (2009) · Advanced Materials · doi:10.1002/adma.200801408 · Cited by 211

Membrane biosensor platforms using nano- and microporous supports

Reimhult, E., & Kumar, K. (2008) · Trends in Biotechnology · doi:10.1016/j.tibtech.2007.11.004 · Cited by 208

Cholesterol biosensor based on cholesterol esterase, cholesterol oxidase and peroxidase immobilized onto conducting polyaniline films

Singh, S., Solanki, P. R., Pandey, M. K., & Malhotra, B. D. (2006) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2005.10.025 · Cited by 206

Biocompatible Functionalization of Polymersome Surfaces: A New Approach to Surface Immobilization and Cell Targeting Using Polymersomes

Egli, S., Nussbaumer, M. G., Balasubramanian, V., Chami, M., Bruns, N., Palivan, C., & Meier, W. (2011) · Journal of the American Chemical Society · doi:10.1021/ja110275f · Cited by 199

pH-sensitive degradable chimaeric polymersomes for the intracellular release of doxorubicin hydrochloride

Du, Y., Chen, W., Zheng, M., Meng, F., & Zhong, Z. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.06.034 · Cited by 195

Emerging methods for the fabrication of polymer capsules

Cui, J., van Koeverden, M. P., Müllner, M., Kempe, K., & Caruso, F. (2014) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2013.10.012 · Cited by 186

Protein Expression, Aggregation, and Triggered Release from Polymersomes as Artificial Cell‐like Structures

Martino, C., Kim, S., Horsfall, L., Abbaspourrad, A., Rosser, S. J., Cooper, J., & Weitz, D. A. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201201443 · Cited by 186

Effect of Bilayer Thickness on Membrane Bending Rigidity

Bermúdez, H., Hammer, D. A., & Discher, D. E. (2004) · Langmuir · doi:10.1021/la035497f · Cited by 184

Ultrasound and pH Dually Responsive Polymer Vesicles for Anticancer Drug Delivery

Chen, W., & Du, J. (2013) · Scientific Reports · doi:10.1038/srep02162 · Cited by 182

Protein–polymer nanoreactors for medical applications

Palivan, C. G., Fischer-Onaca, O., Delcea, M., Itel, F., & Meier, W. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15240h · Cited by 172

Photo‐ and Thermoresponsive Polymersomes for Triggered Release

Amstad, E., Kim, S., & Weitz, D. A. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201206531 · Cited by 171

Blood‐Inert Surfaces via Ion‐Pair Anchoring of Zwitterionic Copolymer Brushes in Human Whole Blood

Chang, Y., Shih, Y., Lai, C., Kung, H., & Jiang, S. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201201386 · Cited by 171

Membrane proteins and proteomics: Love is possible, but so difficult

Rabilloud, T. (2009) · ELECTROPHORESIS · doi:10.1002/elps.200900050 · Cited by 169

Biodegradable Polymersomes

Meng, F., Hiemstra, C., Engbers, G. H. M., & Feijen, J. (2003) · Macromolecules · doi:10.1021/ma034040+ · Cited by 169

A Novel Diblock Copolymer with a Supramolecular Polymer Block and a Traditional Polymer Block: Preparation, Controllable Self‐Assembly in Water, and Application in Controlled Release

Ji, X., Dong, S., Wei, P., Xia, D., & Huang, F. (2013) · Advanced Materials · doi:10.1002/adma.201301654 · Cited by 165

Giant Free-Standing ABA Triblock Copolymer Membranes

Nardin, C., Winterhalter, M., & Meier, W. (2000) · Langmuir · doi:10.1021/la000204t · Cited by 161

Asymmetric ABC‐Triblock Copolymer Membranes Induce a Directed Insertion of Membrane Proteins

Stoenescu, R., Graff, A., & Meier, W. (2004) · Macromolecular Bioscience · doi:10.1002/mabi.200400065 · Cited by 161

Large-scale production of functional membrane proteins

Junge, F., Schneider, B., Reckel, S., Schwarz, D., Dötsch, V., & Bernhard, F. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8067-5 · Cited by 159

Bio-Inspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin

Tai, W., Mo, R., Di, J., Subramanian, V., Gu, X., Buse, J. B., & Gu, Z. (2014) · Biomacromolecules · doi:10.1021/bm500364a · Cited by 158

Aiding Nature’s Organelles: Artificial Peroxisomes Play Their Role

Tanner, P., Balasubramanian, V., & Palivan, C. G. (2013) · Nano Letters · doi:10.1021/nl401215n · Cited by 155

Antibacterial Polypeptide-Grafted Chitosan-Based Nanocapsules As an “Armed” Carrier of Anticancer and Antiepileptic Drugs

Zhou, C., Wang, M., Zou, K., Chen, J., Zhu, Y., & Du, J. (2013) · ACS Macro Letters · doi:10.1021/mz400480z · Cited by 153

Giant Phospholipid/Block Copolymer Hybrid Vesicles: Mixing Behavior and Domain Formation

Nam, J., Beales, P. A., & Vanderlick, T. K. (2010) · Langmuir · doi:10.1021/la103428g · Cited by 150

Electromechanical Limits of Polymersomes

Aranda‐Espinoza, H., Bermudez, H., Bates, F. S., & Discher, D. E. (2001) · Physical Review Letters · doi:10.1103/physrevlett.87.208301 · Cited by 149

Synthesis and Self-Assembly of CO2–Temperature Dual Stimuli-Responsive Triblock Copolymers

Liu, B.-W., Zhou, H., Zhou, S., Zhang, H., Feng, A., Jian, C., Hu, J., Gao, W., & Yuan, J. (2014) · Macromolecules · doi:10.1021/ma5001404 · Cited by 146

Polymersome-Mediated Delivery of Combination Anticancer Therapy to Head and Neck Cancer Cells: 2D and 3D in Vitro Evaluation

Colley, H. E., Hearnden, V. L., Avila-Olias, M., Cecchin, D., Cantón, I., Madsen, J., MacNeil, S., Warren, N. J., Hu, K., McKeating, J. A., et al. (2014) · Molecular Pharmaceutics · doi:10.1021/mp400610b · Cited by 144

Molecular Organization and Dynamics in Polymersome Membranes: A Lateral Diffusion Study

Itel, F., Chami, M., Najer, A., Lörcher, S. L., Wu, D., Dinu, I. A., & Meier, W. P. (2014) · Macromolecules · doi:10.1021/ma5015403 · Cited by 144

Photoresponsive polymersomes as smart, triggerable nanocarriers

Cabane, É., Malinova, V., Menon, S. A., Palivan, C. G., & Meier, W. P. (2011) · Soft Matter · doi:10.1039/c1sm05880k · Cited by 142

Novel aspects of encapsulation and delivery using polymersomes

Messager, L., Gaitzsch, J., Chierico, L., & Battaglia, G. (2014) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2014.09.017 · Cited by 142

Listening to the brain: microelectrode biosensors for neurochemicals

Dale, N., Hatz, S., Tian, F., & Llaudet, E. (2005) · Trends in biotechnology · doi:10.1016/j.tibtech.2005.05.010 · Cited by 139

Polymer-based nanocarriers for vaginal drug delivery

das Neves, J., Nunes, R., Machado, A., & Sarmento, B. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2014.12.004 · Cited by 138

Reduction and temperature dual-responsive crosslinked polymersomes for targeted intracellular protein delivery

Cheng, R., Meng, F., Ma, S., Xu, H., Liu, H., Jing, X., & Zhong, Z. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm13536h · Cited by 138

Mimicking the cell membrane with block copolymer membranes

Zhang, X., Tanner, P., Graff, A., Palivan, C. G., & Meier, W. P. (2012) · Journal of Polymer Science Part A Polymer Chemistry · doi:10.1002/pola.26000 · Cited by 138

Enzymatic Cascade Reactions inside Polymeric Nanocontainers: A Means to Combat Oxidative Stress

Tanner, P., Onaca, O., Balasubramanian, V., Meier, W. P., & Palivan, C. G. (2011) · Chemistry - A European Journal · doi:10.1002/chem.201002782 · Cited by 136

Cross-linked polymersomes as nanoreactors for controlled and stabilized single and cascade enzymatic reactions

Gräfe, D., Gaitzsch, J., Appelhans, D., & Voit, B. I. (2014) · Nanoscale · doi:10.1039/c4nr02155j · Cited by 136

Surface-Grafted Stimuli-Responsive Block Copolymer Brushes for the Thermo-, Photo- and pH-Sensitive Release of Dye Molecules

Kumar, S. K., Dory, Y. L., Lepage, M., & Zhao, Y. (2011) · Macromolecules · doi:10.1021/ma2010102 · Cited by 134

From Membranes to Melts, Rouse to Reptation: Diffusion in Polymersome versus Lipid Bilayers

Lee, J. C., Santore, M. M., Bates, F. S., & Discher, D. E. (2001) · Macromolecules · doi:10.1021/ma0112063 · Cited by 130

pH and Reduction Dual-Bioresponsive Polymersomes for Efficient Intracellular Protein Delivery

Zhang, J., Wu, L., Meng, F., Wang, Z., Deng, C., Liu, H., & Zhong, Z. (2011) · Langmuir · doi:10.1021/la203843m · Cited by 130

Black lipid membranes

Winterhalter, M. (2000) · Current Opinion in Colloid & Interface Science · doi:10.1016/s1359-0294(00)00063-7 · Cited by 128

High-Density Reconstitution of Functional Water Channels into Vesicular and Planar Block Copolymer Membranes

Kumar, M., Habel, J., Shen, Y., Meier, W. P., & Walz, T. (2012) · Journal of the American Chemical Society · doi:10.1021/ja304721r · Cited by 128

Biotechnology Applications of Tethered Lipid Bilayer Membranes

Jackman, J. A., Knoll, W., & Cho, N. (2012) · Materials · doi:10.3390/ma5122637 · Cited by 126

Smart Nanocontainers: Progress on Novel Stimuli‐Responsive Polymer Vesicles

Feng, A., & Yuan, J. (2014) · Macromolecular Rapid Communications · doi:10.1002/marc.201300866 · Cited by 126

Reduction-Responsive Cholesterol-Based Block Copolymer Vesicles for Drug Delivery

Jia, L., Cui, D., Bignon, J. S., Cicco, A. D., Wdzieczak‐Bakala, J., Liu, J., & Li, M. (2014) · Biomacromolecules · doi:10.1021/bm5003569 · Cited by 123

Functionalized polymersomes for biomedical applications

Pawar, P. V., Gohil, S. V., Jain, J. P., & Kumar, N. (2013) · Polymer Chemistry · doi:10.1039/c3py00023k · Cited by 122

Immobilization of laccase onto poly(glycidylmethacrylate) brush grafted poly(hydroxyethylmethacrylate) films: Enzymatic oxidation of phenolic compounds

Bayramoğlu, G., & Arica, M. Y. (2009) · Materials Science and Engineering C · doi:10.1016/j.msec.2009.03.011 · Cited by 122

Enzyme Degradable Polymersomes from Hyaluronic Acid-block-poly(ε-caprolactone) Copolymers for the Detection of Enzymes of Pathogenic Bacteria

Haas, S., Hain, N., Raoufi, M., Handschuh‐Wang, S., Wang, T., Jiang, X., & Schönherr, H. (2015) · Biomacromolecules · doi:10.1021/bm501729h · Cited by 121

Block copolymer self-assembly controlled by the “green” gas stimulus of carbon dioxide

Yan, Q., & Zhao, Y. (2014) · Chemical Communications · doi:10.1039/c4cc03412k · Cited by 120

Folic Acid and Trastuzumab Functionalized Redox Responsive Polymersomes for Intracellular Doxorubicin Delivery in Breast Cancer

Lale, S. V., Kumar, A., Prasad, S., Bharti, A. C., & Koul, V. (2015) · Biomacromolecules · doi:10.1021/acs.biomac.5b00244 · Cited by 120

Protein Adsorption and Cell Adhesion/Detachment Behavior on Dual-Responsive Silicon Surfaces Modified with Poly(N-isopropylacrylamide)-block-polystyrene Copolymer

Yu, Q., Zhang, Y., Chen, H., Zhou, F., Wu, Z., Huang, H., & Brash, J. L. (2010) · Langmuir · doi:10.1021/la904663m · Cited by 119

Polymer nanoreactors shown to produce and release antibiotics locally

Langowska, K., Palivan, C. G., & Meier, W. P. (2012) · Chemical Communications · doi:10.1039/c2cc36345c · Cited by 118

Efficient Encapsulation of Plasmid DNA in pH‐Sensitive PMPC–PDPA Polymersomes: Study of the Effect of PDPA Block Length on Copolymer–DNA Binding Affinity

Lomas, H., Du, J., Cantón, I., Madsen, J., Warren, N. J., Armes, S. P., Lewis, A. L., & Battaglia, G. (2010) · Macromolecular Bioscience · doi:10.1002/mabi.201000083 · Cited by 116

Polymeric Brushes as Functional Templates for Immobilizing Ribonuclease A: Study of Binding Kinetics and Activity

Cullen, S. P., Liu, X., Mandel, I. C., Himpsel, F. J., & Gopalan, P. (2007) · Langmuir · doi:10.1021/la702510z · Cited by 115

Local Membrane Mechanics of Pore-Spanning Bilayers

Mey, I. P., Stephan, M., Schmitt, E. K., Mueller, M. M., Amar, M. B., Steinem, C., & Janshoff, A. (2009) · Journal of the American Chemical Society · doi:10.1021/ja809165h · Cited by 114

Molecular Regulation of Cell-Cycle Progression and Apoptosis in Mammalian Cells: Implications for Biotechnology

Fussenegger, M., & Bailey, J. E. (1998) · Biotechnology Progress · doi:10.1021/bp9800891 · Cited by 114

pH-Sensitive Tubular Polymersomes: Formation and Applications in Cellular Delivery

Robertson, J. D., Yealland, G., Avila-Olias, M., Chierico, L., Bandmann, O., Renshaw, S. A., & Battaglia, G. (2014) · ACS Nano · doi:10.1021/nn5004088 · Cited by 113

Peptide‐Mediated Blood–Brain Barrier Transport of Polymersomes

Georgieva, J. V., Brinkhuis, R. P., Stojanov, K., Weijers, C. A. G. M., Zuilhof, H. T., Rutjes, F. P. J. T., Hoekstra, D., van Hest, J. C. M., & Zuhorn, I. S. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201202001 · Cited by 113

Stimuli-Responsive Polyelectrolyte Polymer Brushes Prepared via Atom-Transfer Radical Polymerization

Ayres, N., Boyes, S. G., & Brittain, W. J. (2006) · Langmuir · doi:10.1021/la061526l · Cited by 110

Encapsulation of Biomacromolecules within Polymersomes by Electroporation

Wang, L., Chierico, L., Little, D., Patikarnmonthon, N., Zhou, Y., Azzouz, M., Madsen, J., Armes, S. P., & Battaglia, G. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201204169 · Cited by 110

Towards an artificial cell

Hammer, D. A., & Kamat, N. P. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.07.044 · Cited by 110

A nanocompartment system (Synthosome) designed for biotechnological applications

Nallani, M., Benito, S. M., Onaca, O., Graff, A., Lindemann, M., Winterhalter, M., Meier, W. P., & Schwaneberg, U. (2005) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2005.10.025 · Cited by 106

Multifunctional polymersomes for cytosolic delivery of gemcitabine and doxorubicin to cancer cells

Nahire, R., Haldar, M. K., Paul, S., Ambre, A. H., Meghnani, V., Layek, B., Katti, K. S., Gange, K. N., Singh, J., Sarkar, K., et al. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.04.026 · Cited by 101

Liposomes: Targeted and Controlled Delivery System

Garg, T., & Goyal, A. K. (2013) · Drug Delivery Letters · doi:10.2174/22103031113036660015 · Cited by 97

Polymersomes Prepared from Thermoresponsive Fluorescent Protein–Polymer Bioconjugates: Capture of and Report on Drug and Protein Payloads

Wong, C. K., Laos, A. J., Soeriyadi, A. H., Wiedenmann, J., Curmi, P. M. G., Gooding, J. J., Marquis, C. P., Stenzel, M. H., & Thordarson, P. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201412406 · Cited by 97

Designer amphiphilic proteins as building blocks for the intracellular formation of organelle-like compartments

Huber, M. C., Schreiber, A. W., von Olshausen, P., Varga, B. R., Kretz, O., Joch, B., Barnert, S., Schubert, R., Eimer, S., Kele, P., et al. (2014) · Nature Materials · doi:10.1038/nmat4118 · Cited by 94

Precision Intracellular Delivery Based on Optofluidic Polymersome Rupture

Vasdekis, A. E., Scott, E. A., O’Neil, C. P., Psaltis, D., & Hubbell, J. A. (2012) · ACS Nano · doi:10.1021/nn302122h · Cited by 94

Polymersomes from Dual Responsive Block Copolymers: Drug Encapsulation by Heating and Acid-Triggered Release

Qiao, Z., Ji, R., Huang, X., Du, F., Zhang, R., Liang, D., & Li, Z. (2013) · Biomacromolecules · doi:10.1021/bm400180n · Cited by 93

Fabrication of Polyion Complex Vesicles with Enhanced Salt and Temperature Resistance and Their Potential Applications as Enzymatic Nanoreactors

Chuanoi, S., Anraku, Y., Hori, M., Kishimura, A., & Kataoka, K. (2014) · Biomacromolecules · doi:10.1021/bm500127g · Cited by 93

Living Unimodal Growth of Polyion Complex Vesicles via Two-Dimensional Supramolecular Polymerization

Anraku, Y., Kishimura, A., Yamasaki, Y., & Kataoka, K. (2013) · Journal of the American Chemical Society · doi:10.1021/ja3096587 · Cited by 93

Improved Tumor Targeting of Polymer-Based Nanovesicles Using Polymer–Lipid Blends

Cheng, Z., Elias, D. R., Kamat, N. P., Johnston, E. D., Poloukhtine, A. A., Popik, V. V., Hammer, D. A., & Tsourkas, A. (2011) · Bioconjugate Chemistry · doi:10.1021/bc200214g · Cited by 92

Enhanced drug delivery to melanoma cells using PMPC-PDPA polymersomes

Pegoraro, C., Cecchin, D., Simón‐Gracia, L., Warren, N. J., Madsen, J., Armes, S. P., Lewis, A. L., MacNeil, S., & Battaglia, G. (2013) · Cancer Letters · doi:10.1016/j.canlet.2013.02.007 · Cited by 91

Covalent immobilization of antibody fragments on well-defined polymer brushes via site-directed method

Iwata, R., Satoh, R., Iwasaki, Y., & Akiyoshi, K. (2007) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2007.10.018 · Cited by 90

Bioreducible polymersomes for intracellular dual-drug delivery

Thambi, T., Deepagan, V. G., Ko, H., Lee, D. S., & Park, J. H. (2012) · Journal of Materials Chemistry · doi:10.1039/c2jm34546c · Cited by 89

Light Responsive Vesicles Based on Linear–Dendritic Block Copolymers Using Azobenzene–Aliphatic Codendrons

Blasco, E., Serrano, J. L., Piñol, M., & Oriol, L. T. (2013) · Macromolecules · doi:10.1021/ma4009725 · Cited by 89

Reduction and pH dual-bioresponsive crosslinked polymersomes for efficient intracellular delivery of proteins and potent induction of cancer cell apoptosis

Sun, H., Meng, F., Cheng, R., Deng, C., & Zhong, Z. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.01.010 · Cited by 88

Black Lipid Membranes: Visualizing the Structure, Dynamics, and Substrate Dependence of Membranes

Ries, R. S., Choi, H., Blunck, R., et al. (2004) · The Journal of Physical Chemistry B · doi:10.1021/jp048098h · Cited by 87

Preparation and characterization of pore-suspending biomimetic membranes embedded with Aquaporin Z on carboxylated polyethylene glycol polymer cushion

Wang, H., Chung, T., Tong, Y. W., Meier, W. P., Chen, Z., Hong, M., Jeyaseelan, K., & Armugam, A. (2011) · Soft Matter · doi:10.1039/c1sm05527e · Cited by 86

Polymersome‐mediated intracellular delivery of antibiotics to treat Porphyromonas gingivalis ‐infected oral epithelial cells

Wayakanon, K., Thornhill, M. H., Douglas, C. W. I., Lewis, A. L., Warren, N. J., Pinnock, A., Armes, S. P., Battaglia, G., & Murdoch, C. (2013) · The FASEB Journal · doi:10.1096/fj.12-225219 · Cited by 85

Asymmetrical Polymer Vesicles with a “Stealthy” Outer Corona and an Endosomal-Escape-Accelerating Inner Corona for Efficient Intracellular Anticancer Drug Delivery

Liu, Q., Chen, J., & Du, J. (2014) · Biomacromolecules · doi:10.1021/bm500676e · Cited by 84

Photolabile plasmonic vesicles assembled from amphiphilic gold nanoparticles for remote-controlled traceable drug delivery

Song, J., Fang, Z., Wang, C., Zhou, J., Duan, B., Pu, L., & Duan, H. (2013) · Nanoscale · doi:10.1039/c3nr01350b · Cited by 83

Graphene Transistors with Multifunctional Polymer Brushes for Biosensing Applications

Hess, L. H., Lyuleeva, A., Blaschke, B. M., et al. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am502112x · Cited by 82

Understanding the function of bacterial outer membrane channels by reconstitution into black lipid membranes

Gelder, P. V., Dumas, F., & Winterhalter, M. (2000) · Biophysical Chemistry · doi:10.1016/s0301-4622(99)00153-2 · Cited by 81

Bioelectrocatalytic System Coupled with Enzyme-Based Biocomputing Ensembles Performing Boolean Logic Operations: Approaching “Smart” Physiologically Controlled Biointerfaces

Zhou, J., Tam, T. K., Pita, M., Ornatska, M., Minko, S., & Katz, E. (2008) · ACS Applied Materials & Interfaces · doi:10.1021/am800088d · Cited by 80

Key Roles for Chain Flexibility in Block Copolymer Membranes that Contain Pores or Make Tubes

Srinivas, G., Discher, D. E., & Klein, M. L. (2005) · Nano Letters · doi:10.1021/nl051515x · Cited by 79

Anisamide-Decorated pH-Sensitive Degradable Chimaeric Polymersomes Mediate Potent and Targeted Protein Delivery to Lung Cancer Cells

Lu, L., Zou, Y., Yang, W., Meng, F., Deng, C., Cheng, R., & Zhong, Z. (2015) · Biomacromolecules · doi:10.1021/acs.biomac.5b00193 · Cited by 79

ROP and ATRP Fabricated Dual Targeted Redox Sensitive Polymersomes Based on pPEGMA-PCL-ss-PCL-pPEGMA Triblock Copolymers for Breast Cancer Therapeutics

Kumar, A., Lale, S. V., Mahajan, S., Choudhary, V., & Koul, V. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b01731 · Cited by 78

A glucose sensor via stable immobilization of the GOx enzyme on an organic transistor using a polymer brush

Welch, M., Doublet, T., Bernard, C., Malliaras, G. G., & Ober, C. K. (2014) · Journal of Polymer Science Part A Polymer Chemistry · doi:10.1002/pola.27392 · Cited by 78

Can polymeric vesicles that confine enzymatic reactions act as simplified organelles?

Tanner, P., Egli, S., Balasubramanian, V., Onaca, O., Palivan, C. G., & Meier, W. P. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.05.003 · Cited by 76

Gradient immobilization of a cell adhesion RGD peptide on thermal responsive surface for regulating cell adhesion and detachment

Li, L., Wu, J., & Gao, C. (2010) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2010.09.028 · Cited by 75

Single molecule measurements of channel proteins incorporated into biomimetic polymer membranes

Wong, D., Jeon, T., & Schmidt, J. J. (2006) · Nanotechnology · doi:10.1088/0957-4484/17/15/016 · Cited by 75

Fully synthetic polymer vesicles for intracellular delivery of antibodies in live cells

Cantón, I., Massignani, M., Patikarnmonthon, N., Chierico, L., Robertson, J., Renshaw, S. A., Warren, N. J., Madsen, J., Armes, S. P., Lewis, A. L., et al. (2012) · The FASEB Journal · doi:10.1096/fj.12-212183 · Cited by 73

Nanomimics of Host Cell Membranes Block Invasion and Expose Invasive Malaria Parasites

Najer, A., Wu, D., Bieri, A., Brand, F., Palivan, C. G., Beck, H., & Meier, W. P. (2014) · ACS Nano · doi:10.1021/nn5054206 · Cited by 71

Membrane Solubilization by Detergent: Resistance Conferred by Thickness

Pata, V., Ahmed, F., Discher, D. E., & Dan, N. R. (2004) · Langmuir · doi:10.1021/la035734e · Cited by 70

Amphiphilic Copolymer Membranes Promote NADH:Ubiquinone Oxidoreductase Activity: Towards an Electron‐Transfer Nanodevice

Graff, A., Fraysse‐Ailhas, C., Palivan, C. G., Grzelakowski, M., Friedrich, T., Vebert, C., Gescheidt, G., & Meier, W. P. (2009) · Macromolecular Chemistry and Physics · doi:10.1002/macp.200900517 · Cited by 69

Bio-mimetic Nanostructure Self-assembled from Au@Ag Heterogeneous Nanorods and Phage Fusion Proteins for Targeted Tumor Optical Detection and Photothermal Therapy

Wang, F., Liu, P., Sun, L. N., Li, C., Petrenko, V. A., & Liu, A. (2014) · Scientific Reports · doi:10.1038/srep06808 · Cited by 68

pH-Responsive Chimaeric Pepsomes Based on Asymmetric Poly(ethylene glycol)-b-Poly( l -leucine)-b-Poly( l -glutamic acid) Triblock Copolymer for Efficient Loading and Active Intracellular Delivery of Doxorubicin Hydrochloride

Chen, P., Qiu, M., Deng, C., Meng, F., Zhang, J., Cheng, R., & Zhong, Z. (2015) · Biomacromolecules · doi:10.1021/acs.biomac.5b00113 · Cited by 65

Enzyme Immobilization Strategies and Electropolymerization Conditions to Control Sensitivity and Selectivity Parameters of a Polymer-Enzyme Composite Glucose Biosensor

Rothwell, S. A., Killoran, S. J., & O'Neill, R. D. (2010) · Sensors · doi:10.3390/s100706439 · Cited by 65

Functionalized Nanocompartments (Synthosomes) with a Reduction‐Triggered Release System

Onaca, O., Sarkar, P., Roccatano, D., Friedrich, T., Hauer, B., Grzelakowski, M., Güven, A., Fioroni, M., & Schwaneberg, U. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200801076 · Cited by 64

Reconstitution of Membrane Proteins into Polymer-Supported Membranes for Probing Diffusion and Interactions by Single Molecule Techniques

Roder, F., Waichman, S., Paterok, D., Schubert, R., Richter, C. P., Liedberg, B., & Piehler, J. (2011) · Analytical Chemistry · doi:10.1021/ac201294v · Cited by 63

Phase Behavior of Mixed Langmuir Monolayers from Amphiphilic Block Copolymers and an Antimicrobial Peptide

Haefele, T., Kita‐Tokarczyk, K., & Meier, W. P. (2005) · Langmuir · doi:10.1021/la0524216 · Cited by 63

Poly(2-hydroxyethyl methacrylate) for Enzyme Immobilization: Impact on Activity and Stability of Horseradish Peroxidase

Lane, S. M., Kuang, Z., Yom, J., Arifuzzaman, S., Genzer, J., Farmer, B. L., Naik, R. R., & Vaia, R. A. (2011) · Biomacromolecules · doi:10.1021/bm200173y · Cited by 62

Polymersomes conjugated to 83-14 monoclonal antibodies: Invitro targeting of brain capillary endothelial cells

Dieu, L., Wu, D., Palivan, C. G., Balasubramanian, V., & Huwyler, J. (2014) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2014.05.021 · Cited by 59

Polymer Nanocompartments in Broad-Spectrum Medical Applications

Najer, A., Wu, D., Vasquez‐Muñoz, D., Palivan, C. G., & Meier, W. P. (2013) · Nanomedicine · doi:10.2217/nnm.13.11 · Cited by 59

GrapheneTransistors with Multifunctional PolymerBrushes for Biosensing Applications

Hess, L. H., Lyuleeva, A., Blaschke, B. M., et al. (2014) · doi:10.1021/am502112x.s001 · Cited by 59

Structural and mechanical characteristics of polymersomes

Chang, H.-Y., Sheng, Y., & Tsao, H. (2014) · Soft Matter · doi:10.1039/c4sm01092b · Cited by 57

Mechanical properties of block copolymer vesicle membranes by atomic force microscopy

Chen, Q., Schönherr, H., & Vancso, G. J. (2009) · Soft Matter · doi:10.1039/b903110c · Cited by 55

Polysaccharide nano-vesicular multidrug carriers for synergistic killing of cancer cells

Pramod, P. S., Shah, R., Chaphekar, S., Balasubramanian, N., & Jayakannan, M. (2014) · Nanoscale · doi:10.1039/c4nr03514c · Cited by 54

Protein Immobilization on Epoxy-Activated Thin Polymer Films: Effect of Surface Wettability and Enzyme Loading

Chen, B., Pernodet, N., Rafailovich, M. H., Bakhtina, A., & Gross, R. A. (2008) · Langmuir · doi:10.1021/la8019952 · Cited by 53

Robust formation of biodegradable polymersomes by direct hydration

Sui, X., Kujala, P., Janssen, G.-J. A., de Jong, E., Zuhorn, I. S., & van Hest, J. C. M. (2014) · Polymer Chemistry · doi:10.1039/c4py01288g · Cited by 53

Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy

Ma, J., Luan, S., Song, L., Jin, J., Yuan, S., Yan, S., Yang, H., Shi, H., & Yin, J. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am405017h · Cited by 53

Enzyme-mediated amperometric biosensors prepared via successive surface-initiated atom-transfer radical polymerization

Zhang, Z., Yuan, S., Zhu, X., Neoh, K. G., & Kang, E. T. (2009) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2009.09.023 · Cited by 51

Polymer Nanoreactors with Dual Functionality: Simultaneous Detoxification of Peroxynitrite and Oxygen Transport

Dobrunz, D., Toma, A. C., Tanner, P., Pfohl, T., & Palivan, C. G. (2012) · Langmuir · doi:10.1021/la302724m · Cited by 51

In Vivo Biodistribution of Prion- and GM1-Targeted Polymersomes following Intravenous Administration in Mice

Stojanov, K., Georgieva, J. V., Brinkhuis, R. P., van Hest, J. C. M., Rutjes, F. P. J. T., Dierckx, R., de Vries, E. F. J., & Zuhorn, I. S. (2012) · Molecular Pharmaceutics · doi:10.1021/mp200621v · Cited by 51

Planar Block Copolymer Membranes by Vesicle Spreading

Dorn, J., Belegrinou, S., Kreiter, M., Sinner, E., & Meier, W. P. (2011) · Macromolecular Bioscience · doi:10.1002/mabi.201000396 · Cited by 50

Planar Biomimetic Membranes Based on Amphiphilic Block Copolymers

Kowal, J., Zhang, X., Dinu, I. A., Palivan, C. G., & Meier, W. P. (2013) · ACS Macro Letters · doi:10.1021/mz400590c · Cited by 49

Probing bioinspired transport of nanoparticles into polymersomes.

Jaskiewicz, K., Larsen, A., Lieberwirth, I., Koynov, K., Meier, W., Fytas, G., Kroeger, A., & Landfester, K. (2012) · Angewandte Chemie · doi:10.1002/anie.201108421 · Cited by 49

Switchable Vesicles Formed by Diblock Random Copolymers with Tunable pH- and Thermo-Responsiveness

Savoji, M. T., Strandman, S., & Zhu, X. X. (2013) · Langmuir · doi:10.1021/la4009625 · Cited by 49

Engineering therapeutic proteins for cell entry: the natural approach

Guillard, S., Minter, R., & Jackson, R. H. (2015) · Trends in biotechnology · doi:10.1016/j.tibtech.2014.12.004 · Cited by 48

The Management of Hyperuricemia and Gout in Patients with Heart Failure

Spieker, L. E., Ruschitzka, F. T., Lüscher, T. F., & Noll, G. (2002) · European Journal of Heart Failure · doi:10.1016/s1388-9842(02)00086-7 · Cited by 48

Proton Transport from Dendritic Helical‐Pore‐Incorporated Polymersomes

Kim, A. J., Kaucher, M. S., Davis, K. P., Peterca, M., Imam, M. R., Christian, N. A., Levine, D. H., Bates, F. S., Percec, V., & Hammer, D. A. (2009) · Advanced Functional Materials · doi:10.1002/adfm.200900076 · Cited by 46

Kinetics of pH-Induced Formation and Dissociation of Polymeric Vesicles Assembled from a Water-Soluble Zwitterionic Diblock Copolymer

Shen, L., Du, J., Armes, S. P., & Liu, S. (2008) · Langmuir · doi:10.1021/la801190z · Cited by 45

Functional surface engineering by nucleotide-modulated potassium channel insertion into polymer membranes attached to solid supports

Kowal, J., Kowal, J., Wu, D., Stahlberg, H., Palivan, C. G., & Meier, W. P. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.05.043 · Cited by 44

Dendrimersomes with photodegradable membranes for triggered release of hydrophilic and hydrophobic cargo

Nazemi, A., & Gillies, E. R. (2014) · Chemical Communications · doi:10.1039/c4cc05161k · Cited by 44

Control of Frictional Coupling of Transmembrane Cell Receptors in Model Cell Membranes with Linear Polymer Spacers

Purrucker, O., Förtig, A., Jordan, R., Sackmann, E., & Tanaka, M. (2007) · Physical Review Letters · doi:10.1103/physrevlett.98.078102 · Cited by 44

Polymersomes functionalized via “click” chemistry with the fibronectin mimetic peptides PR_b and GRGDSP for targeted delivery to cells with different levels of α5β1 expression

Pangburn, T. O., Bates, F. S., & Kokkoli, E. (2012) · Soft Matter · doi:10.1039/c2sm06922a · Cited by 44

Self-Directed Reconstitution of Proteorhodopsin with Amphiphilic Block Copolymers Induces the Formation of Hierarchically Ordered Proteopolymer Membrane Arrays

Hua, D., Kuang, L., & Liang, H. (2011) · Journal of the American Chemical Society · doi:10.1021/ja109796x · Cited by 41

Amphiphilic Diblock Copolymers for Molecular Recognition: Metal−Nitrilotriacetic Acid Functionalized Vesicles

Nehring, R., Palivan, C. G., Casse, O., Tanner, P., Tüxen, J., & Meier, W. P. (2008) · Langmuir · doi:10.1021/la8027308 · Cited by 40

Smart polymer brush nanostructures guide the self-assembly of pore-spanning lipid bilayers with integrated membrane proteins

de Groot, G. W., Demarche, S. F., Santonicola, M. G., Tiefenauer, L., & Vancso, G. J. (2013) · Nanoscale · doi:10.1039/c3nr05356c · Cited by 40

Synthetic biology, inspired by synthetic chemistry

Malinova, V., Nallani, M., Meier, W. P., & Sinner, E.-K. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.05.033 · Cited by 37

Bioactive Polymersomes Self-Assembled from Amphiphilic PPO-GlycoPolypeptides: Synthesis, Characterization, and Dual-Dye Encapsulation

Das, S., Sharma, D. K., Chakrabarty, S., Chowdhury, A., & Gupta, S. S. (2015) · Langmuir · doi:10.1021/la503993e · Cited by 37

Sequential pH‐Dependent Adsorption of Ionic Amphiphilic Diblock Copolymer Micelles and Choline Oxidase Onto Conductive Substrates: Toward the Design of Biosensors

Sigolaeva, L. V., Günther, U., Pergushov, D. V., et al. (2014) · Macromolecular Bioscience · doi:10.1002/mabi.201300580 · Cited by 35

Oriented Binding of the His6-Tagged Carboxyl-Tail of the L-type Ca2+ Channel α1-Subunit to a New NTA-Functionalized Self-Assembled Monolayer

Gamsjaeger, R., Wimmer, B., Kahr, H., Tinazli, A., Pićurić, S., Lata, S., Tampé, R., Maulet, Y., Gruber, H. J., Hinterdorfer, P., et al. (2004) · Langmuir · doi:10.1021/la0498206 · Cited by 35

Controlled enhancement of transmembrane enzyme activity in polymer cushioned supported bilayer membranes

Renner, L. D., Pompe, W., Lemaitre, R., Drechsel, D. N., & Werner, C. (2010) · Soft Matter · doi:10.1039/c0sm00565g · Cited by 35

Microbial lipases and their industrial applications: a comprehensive review

Chandra, P., Enespa, Singh, R., & Arora, P. K. (2020) · Microbial Cell Factories · doi:10.1186/s12934-020-01428-8 · Cited by 887

Artificial Metalloenzymes: Reaction Scope and Optimization Strategies

Schwizer, F., Okamoto, Y., Heinisch, T., Gu, Y., Pellizzoni, M. M., Lebrun, V., Reuter, R., Köhler, V., Lewis, J. C., & Ward, T. R. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00014 · Cited by 831

Opportunities and challenges for combining chemo- and biocatalysis

Rudroff, F., Mihovilovic, M. D., Gröger, H., Snajdrova, R., Iding, H., & Bornscheuer, U. T. (2018) · Nature Catalysis · doi:10.1038/s41929-017-0010-4 · Cited by 649

H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery

Hu, X., Yu, J., Qian, C., Lu, Y., Kahkoska, A. R., Xie, Z., Jing, X., Buse, J. B., & Gu, Z. (2017) · ACS Nano · doi:10.1021/acsnano.6b06892 · Cited by 313

Preparation and Application of Cell Membrane-Camouflaged Nanoparticles for Cancer Therapy

Zhai, Y., Su, J., Ran, W., Zhang, P., Yin, Q., Zhang, Z., Yu, H., & Li, Y. (2017) · Theranostics · doi:10.7150/thno.20118 · Cited by 312