Coffee drinking and death due to coronary heart disease
Abstract
For a series of 649 patients who died of coronary heart disease within 24 hours of onset of symptoms, and an equal number of neighborhood controls, information was obtained on a large number of variables, including coffee consumption. An analysis using multivariate risk scores to control for all available variables yields a maximum likelihood estimate of the risk ratio associated with coffee drinking of 1.1 (95 per cent two-sided confidence limits, 0.8 to 1.6). The estimate of the risk ratio depends somewhat on the number and nature of variables controlled for in the analysis. Overall, our findings, limited to low-risk and middle-risk patients, suggest that the risk, if any, of death from coronary heart disease associated with coffee drinking is small.
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With one exception, all of the case-control studies used non-fatal myocardial infarction as the disease end point.
“With one exception,'6 all of the case-control studies used non-fatal myocardial infarction as the disease end point.”
From Does coffee drinking increase the risk of coronary heart disease? Results from a meta‐analysis (1994) · cites this paper as [36]
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- Authors
- Hennekens, C. H., Drolette, M. E., Jesse, M. J., Davies, J. E., & Hutchison, G. B.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1976-03-18
- Volume
- 294
- Issue
- 12
- Pages
- 633-636
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2336729671
- Cited by
- 101
- References
- 15
- Citations by year
- 2022: 1 · 2021: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2013: 3 · 2012: 1
- FWCI
- 10.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- coffee consumption, coronary artery disease, mortality, relative risk, case-control study, risk factors
- MeSH terms
- Adult, Aged, Angina Pectoris, Body Weight, Caffeine, Coffee, Coronary Disease, Physical Exertion, Heart Failure, Humans, Hypertension, Male, Medical History Taking, Middle Aged, Myocardial Infarction, Occupations, Regression Analysis, Risk, Smoking, Diabetes Complications
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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