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Cited by 480

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Diet and 20-Year Mortality from Coronary Heart Disease: The Ireland–Boston Diet–Heart Study

Kushi, Lawrence H., Lew, Robert A., Stare, Fredrick J., Ellison, Curtis R., el Lozy, Mohamed, Bourke, Geoffrey, Daly, Leslie, Graham, Ian, Hickey, Noel, Mulcahy, Risteard, Kevaney, John·1985·New England Journal of Medicine
DOI 10.1056/nejm198503283121302
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Abstract

In a prospective epidemiologic study of 1001 middle-aged men, we examined the relation between dietary information collected approximately 20 years ago and subsequent mortality from coronary heart disease. The men were initially enrolled in three cohorts: one of men born and living in Ireland, another of those born in Ireland who had emigrated to Boston, and the third of those born in the Boston area of Irish immigrants. There were no differences in mortality from coronary heart disease among the three cohorts. In within-population analyses, those who died of coronary heart disease had higher Keys (P = 0.06) and modified Hegsted (P = 0.02) dietary scores than did those who did not (a high score indicates a high intake of saturated fatty acids and cholesterol and a relatively low intake of polyunsaturated fatty acids). These associations were significant (P = 0.03 for the Keys and P = 0.04 for the modified Hegsted scores) after adjustment for other risk factors for coronary heart disease. Fiber intake (P = 0.04) and a vegetable-foods score, which rose with increased intake of fiber, vegetable protein, and starch (P = 0.02), were lower among those who died from coronary heart disease, though not significantly so after adjustment for other risk factors. A higher Keys score carried an increased risk of coronary heart disease (relative risk, 1.60), and a higher fiber intake carried a decreased risk (relative risk, 0.57). Overall, these results tend to support the hypothesis that diet is related, albeit weakly, to the development of coronary heart disease.

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Metadata

Authors
Kushi, L. H., Lew, R. A., Stare, F. J., Ellison, C. R., el Lozy, M., Bourke, G., Daly, L., Graham, I., Hickey, N., Mulcahy, R., & Kevaney, J.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1985-03-28
Volume
312
Issue
13
Pages
811-818
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm198503283121302
OpenAlex
W2044486889
Cited by
480
References
1
FWCI
25.77
Type
journal article
Language
en
Open access
closed

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