Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis
Sanyal, Arun J., Chalasani, Naga, Kowdley, Kris V., McCullough, Arthur, Diehl, Anna Mae, Bass, Nathan M., Neuschwander-Tetri, Brent A., Lavine, Joel E. +8 more·2010·New England Journal of Medicine
Cited by (180)
Items 101–180 of 180
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- Fibrosis progression rate in biopsy-proven nonalcoholic fatty liver disease among people with diabetes versus people without diabetes: a multicenter studyHuang, Daniel Q., Wilson, Laura A., Behling, Cynthia, Kleiner, David E., Kowdley, Kris V., Dasarathy, Srinivasan, Amangurbanova, Maral, Terrault, Norah A., Diehl, Anna Mae, Chalasani, Naga et al. · 2023 · Gastroenterology
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- IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent mannerNishizawa, Hitoshi, Iguchi, Genzo, Fukuoka, Hidenori, Takahashi, Michiko, Suda, Kentaro, Bando, Hironori, Matsumoto, Ryusaku, Yoshida, Kenichi, Odake, Yukiko, Ogawa, Wataru et al. · 2016 · Scientific Reports
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- Placebo-controlled, randomised clinical trial: High-dose resveratrol treatment for non-alcoholic fatty liver diseaseHeebøll, Sara, Kreuzfeldt, Martin, Hamilton-Dutoit, Stephen, Kjær Poulsen, Marianne, Stødkilde-Jørgensen, Hans, Møller, Holger Jon, Jessen, Niels, Thorsen, Kasper, Kristina Hellberg, Ylva, Bønløkke Pedersen, Steen et al. · 2016 · Scandinavian Journal of Gastroenterology
- Efficacy and safety of anti-hyperglycaemic drugs in patients with non-alcoholic fatty liver disease with or without diabetes: An updated systematic review of randomized controlled trialsMantovani, A., Byrne, C.D., Scorletti, E., Mantzoros, C.S., Targher, G. · 2020 · Diabetes & Metabolism
- The effectiveness of liraglutide in nonalcoholic fatty liver disease patients with type 2 diabetes mellitus compared to sitagliptin and pioglitazoneOhki, Takamasa, Isogawa, Akihiro, Iwamoto, Masahiko, Ohsugi, Mitsuru, Yoshida, Haruhiko, Toda, Nobuo, Tagawa, Kazumi, Omata, Masao, Koike, Kazuhiko · 2012 · The Scientific World Journal
- Lipid metabolism in MASLD and MASH: From mechanism to the clinicCarli, Fabrizia, Della Pepa, Giuseppe, Sabatini, Silvia, Vidal Puig, Antonio, Gastaldelli, Amalia · 2024 · JHEP Reports
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- Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosisYu, Junjie, Zhu, Changyu, Wang, Xiaobo, Kim, KyeongJin, Bartolome, Alberto, Dongiovanni, Paola, Yates, Katherine P., Valenti, Luca, Carrer, Michele, Sadowski, Thorsten et al. · 2021 · Science Translational Medicine
- Obeticholic acid-a new therapy in PBC and NASHChapman, Roger W, Lynch, Kate D · 2020 · British Medical Bulletin
- Effects of combined exenatide and pioglitazone therapy on hepatic fat content in type 2 diabetesSathyanarayana, Padma, Jogi, Medhavi, Muthupillai, Raja, Krishnamurthy, Ramkumar, Samson, Susan L., Bajaj, Mandeep · 2011 · Obesity
- Non-alcoholic Fatty Liver Disease (NAFLD) as a Neglected Metabolic Companion of Psychiatric Disorders: Common Pathways and Future ApproachesSoto-Angona, Óscar, Anmella, Gerard, Valdés-Florido, María José, De Uribe-Viloria, Nieves, Carvalho, Andre F., Penninx, Brenda W. J. H., Berk, Michael · 2020 · BMC Medicine
- EDP-305 in patients with NASH: a phase II double-blind placebo-controlled dose-ranging studyRatziu, Vlad, Rinella, Mary E., Neuschwander-Tetri, Brent A., Lawitz, Eric, Denham, Douglas, Kayali, Zeid, Sheikh, Aasim, Kowdley, Kris V., Desta, Taddese, Elkhashab, Magdy et al. · 2022 · Journal of Hepatology
- Relationship Between Changes in Serum Levels of Keratin 18 and Changes in Liver Histology in Children and Adults With Nonalcoholic Fatty Liver DiseaseVuppalanchi, Raj, Jain, Ajay K., Deppe, Ross, Yates, Katherine, Comerford, Megan, Masuoka, Howard C., Neuschwander-Tetri, Brent A., Loomba, Rohit, Brunt, Elizabeth M., Kleiner, David E. et al. · 2014 · Clinical Gastroenterology and Hepatology
- Understanding the cellular interactome of non-alcoholic fatty liver diseaseWallace, Sebastian J., Tacke, Frank, Schwabe, Robert F., Henderson, Neil C. · 2022 · JHEP Reports
- A CONSORT-Compliant, Randomized, Double-Blind, Placebo-Controlled Pilot Trial of Purified Anthocyanin in Patients With Nonalcoholic Fatty Liver DiseaseZhang, Pei-Wen, Chen, Feng-Xia, Li, Di, Ling, Wen-Hua, Guo, Hong-Hui · 2015 · Medicine
- Hepatocellular carcinoma in the setting of non-cirrhotic nonalcoholic fatty liver disease and the metabolic syndrome: US experiencePerumpail, Ryan B., Wong, Robert J., Ahmed, Aijaz, Harrison, Stephen A. · 2015 · Digestive Diseases and Sciences
- Nonalcoholic fatty liver disease – current status and future directionsDemir, Münevver, Lang, Sonja, Steffen, Hans‐Michael · 2015 · Journal of Digestive Diseases
- The effect of coffee consumption on the non-alcoholic fatty liver disease and liver fibrosis: a meta-analysis of 11 epidemiological studiesHayat, Umar, Siddiqui, Ali A., Okut, Hayrettin, Afroz, Saba, Tasleem, Syed, Haris, Ahmed · 2021 · Annals of Hepatology
- International liver transplantation consensus statement on end-stage liver disease due to nonalcoholic steatohepatitis and liver transplantationTsochatzis, Emmanuel, Coilly, Audrey, Nadalin, Silvio, Levistky, Josh, Tokat, Yaman, Ghobrial, Mark, Klinck, John, Berenguer, Marina · 2019 · Transplantation
- Improved hepatic lipid composition following short-term exercise in nonalcoholic fatty liver diseaseHaus, Jacob M., Solomon, Thomas P.J., Kelly, Karen R., Fealy, Ciaran E., Kullman, Emily L., Scelsi, Amanda R., Lu, Lan, Pagadala, Mangesh R., McCullough, Arthur J., Flask, Chris A. et al. · 2013 · The Journal of Clinical Endocrinology & Metabolism
- Pharmacological intervention in hepatic stellate cell activation and hepatic fibrosisSchon, Hans-Theo, Bartneck, Matthias, Borkham-Kamphorst, Erawan, Nattermann, Jacob, Lammers, Twan, Tacke, Frank, Weiskirchen, Ralf · 2016 · Frontiers in Pharmacology
- Liver safety of statins in prediabetes or T2DM and nonalcoholic steatohepatitis: post hoc analysis of a randomized trialBril, Fernando, Portillo Sanchez, Paola, Lomonaco, Romina, Orsak, Beverly, Hecht, Joan, Tio, Fermin, Cusi, Kenneth · 2017 · The Journal of Clinical Endocrinology & Metabolism
- The Multifaceted Roles of Macrophages in NAFLD PathogenesisVonderlin, Joscha, Chavakis, Triantafyllos, Sieweke, Michael, Tacke, Frank · 2023 · Cellular and Molecular Gastroenterology and Hepatology
- Nutrition in the management of cirrhosis and its neurological complicationsBémeur, Chantal, Butterworth, Roger F. · 2014 · Journal of Clinical and Experimental Hepatology
- Evaluation of PXL065–deuterium-stabilized (R)-pioglitazone in patients with NASH: a phase II randomized placebo-controlled trial (DESTINY-1)Harrison, Stephen A., Thang, Carole, Bolze, Sébastien, Dewitt, Sheila, Hallakou-Bozec, Sophie, Dubourg, Julie, Bedossa, Pierre, Cusi, Kenneth, Ratziu, Vlad, Grouin, Jean-Marie et al. · 2023 · Journal of Hepatology
- Systematic review with network meta-analysis: comparative efficacy of pharmacologic therapies for fibrosis improvement and resolution of NASHMajzoub, Abdul M., Nayfeh, Tarek, Barnard, Abbey, Munaganuru, Nagambika, Dave, Shravan, Singh, Siddharth, Murad, Mohammad Hassan, Loomba, Rohit · 2021 · Alimentary Pharmacology & Therapeutics
- Standardisation of diet and exercise in clinical trials of NAFLD-NASH: Recommendations from the Liver ForumGlass, Oliver, Filozof, Claudia, Noureddin, Mazen, Berner-Hansen, Mark, Schabel, Elmer, Omokaro, Stephanie O., Schattenberg, Jörn M., Barradas, Katherine, Miller, Veronica, Francque, Sven et al. · 2020 · Journal of Hepatology
- Why Do So Many Nonalcoholic Steatohepatitis Trials Fail?Ratziu, Vlad, Friedman, Scott L. · 2023 · Gastroenterology
- Vildagliptin and Pioglitazone in Patients With Impaired Glucose Tolerance After Kidney Transplantation: A Randomized, Placebo-Controlled Clinical TrialWerzowa, Johannes, Hecking, Manfred, Haidinger, Michael, Lechner, Felix, Döller, Dominik, Pacini, Giovanni, Stemer, Gunar, Pleiner, Johannes, Frantal, Sophie, Säemann, Marcus D. · 2013 · Transplantation
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- Antibody-Directed Glucocorticoid Targeting to CD163 in M2-Type Macrophages Attenuates Fructose-Induced Liver Inflammatory ChangesSvendsen, Pia, Graversen, Jonas H., Etzerodt, Anders, Hager, Henrik, Røge, Rasmus, Grønbæk, Henning, Christensen, Erik I., Møller, Holger J., Vilstrup, Hendrik, Moestrup, Søren K. · 2017 · Molecular Therapy - Methods & Clinical Development
- Pioglitazone even at low dosage improves NAFLD in type 2 diabetes: clinical and pathophysiological insights from a subgroup of the TOSCA.IT randomised trialDella Pepa, Giuseppe, Russo, Marco, Vitale, Marilena, Carli, Fabrizia, Vetrani, Claudia, Masulli, Maria, Riccardi, Gabriele, Vaccaro, Olga, Gastaldelli, Amalia, Rivellese, Angela A. et al. · 2021 · Diabetes Research and Clinical Practice
- Screening for nonalcoholic steatohepatitis in individuals with type 2 diabetes: a cost-effectiveness analysisCorey, Kathleen E., Klebanoff, Matthew J., Tramontano, Angela C., Chung, Raymond T., Hur, Chin · 2016 · Digestive Diseases and Sciences
- An Evaluation of the Collagen Fragments Related to Fibrogenesis and Fibrolysis in Nonalcoholic SteatohepatitisLuo, Yi, Oseini, Abdul, Gagnon, Robert, Charles, Edgar D., Sidik, Kurex, Vincent, Robert, Collen, Rebeca, Idowu, Michael, Contos, Melissa J., Mirshahi, Faridoddin et al. · 2018 · Scientific Reports
- Do thiazolidinediones still have a role in treatment of type 2 diabetes mellitus?Consoli, A., Formoso, G. · 2013 · Diabetes, Obesity and Metabolism
- A critical review of endpoints for non-cirrhotic NASH therapeutic trialsRatziu, Vlad · 2018 · Journal of Hepatology
- Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activityGuy, Cynthia D., Suzuki, Ayako, Abdelmalek, Manal F., Burchette, James L., Diehl, Anna Mae, for the NASH CRN · 2015 · Hepatology
- Efficacy and safety of glucagon-like peptide-1 receptor agonists in non-alcoholic fatty liver disease: A systematic review and meta-analysisDong, Yajie, Lv, Qingguo, Li, Sheyu, Wu, Yuan, Li, Ling, Li, Juan, Zhang, Fang, Sun, Xin, Tong, Nanwei · 2017 · Clinics and Research in Hepatology and Gastroenterology
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- Cost-effectiveness analysis: risk stratification of nonalcoholic fatty liver disease (NAFLD) by the primary care physician using the NAFLD fibrosis scoreTapper, Elliot B., Hunink, M. G. Myriam, Afdhal, Nezam H., Lai, Michelle, Sengupta, Neil · 2016 · PLoS ONE
- Pioglitazone and bariatric surgery are the most effective treatments for non-alcoholic steatohepatitis: a hierarchical network meta-analysisPanunzi, Simona, Maltese, Sabina, Verrastro, Ornella, Labbate, Luca, De Gaetano, Andrea, Pompili, Maurizio, Capristo, Esmeralda, Bornstein, Stefan R., Mingrone, Geltrude · 2021 · Diabetes, Obesity and Metabolism
- Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry–based metabolomicsJohnson, Caroline H, Slanař, Ondřej, Krausz, Kristopher W, Kang, Dong Wook, Patterson, Andrew D, Kim, Jung-Hwan, Luecke, Hans, Gonzalez, Frank J, Idle, Jeffrey R · 2012 · The American Journal of Clinical Nutrition
- Plasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatoninGonciarz, Maciej, Bielański, Wladyslaw, Partyka, Robert, Brzozowski, Tomasz, Konturek, Piotr C., Eszyk, Jerzy, Celiński, Krzysztof, Reiter, Russel J., Konturek, Stanislaw J. · 2013 · Journal of Pineal Research
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- Change in hepatic fat content measured by MRI does not predict treatment-induced histological improvement of steatohepatitisBril, Fernando, Barb, Diana, Lomonaco, Romina, Lai, Jinping, Cusi, Kenneth · 2020 · Journal of Hepatology
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- Insulin Resistance Is Central to Long-Term Reversal of Histologic Nonalcoholic Steatohepatitis After Metabolic SurgeryRusso, Maria Francesca, Lembo, Erminia, Mari, Andrea, Angelini, Giulia, Verrastro, Ornella, Nanni, Giuseppe, Pompili, Maurizio, Raffaelli, Marco, Vecchio, Fabio Maria, Bornstein, Stefan R et al. · 2021 · The Journal of Clinical Endocrinology & Metabolism
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- Nonalcoholic steatohepatitis Fitness Intervention in Thrombosis (NASHFit): Study protocol for a randomized controlled trial of a supervised aerobic exercise program to reduce elevated clotting risk in patients with NASHStine, Jonathan G., Schreibman, Ian, Navabi, Seyedehsan, Kang, Mitchell, Dahmus, Jessica, Soriano, Christopher, Rivas, Gloriany, Hummer, Breianna, Beyer, Megan, Tressler, Heather et al. · 2020 · Contemporary Clinical Trials Communications
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