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Cited by 1,408Cancer survivorship and careMental Health Treatment and AccessCancer-related cognitive impairment studies

Prevalence of depression in patients with cancer

Open access
Massie, M. J.·2004·Journal of the National Cancer Institute Monographs
DOI 10.1093/jncimonographs/lgh014
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Abstract

Depression is the psychiatric syndrome that has received the most attention in individuals with cancer. The study of depression has been a challenge because symptoms occur on a broad spectrum that ranges from sadness to major affective disorder and because mood change is often difficult to evaluate when a patient is confronted by repeated threats to life, is receiving cancer treatments, is fatigued, or is experiencing pain. Although many research groups have assessed depression in cancer patients since the 1960s, the reported prevalence (major depression, 0%-38%; depression spectrum syndromes, 0%-58%) varies significantly because of varying conceptualizations of depression, different criteria used to define depression, differences in methodological approaches to the measurement of depression, and different populations studied. Depression is highly associated with oropharyngeal (22%-57%), pancreatic (33%-50%), breast (1.5%-46%), and lung (11%-44%) cancers. A less high prevalence of depression is reported in patients with other cancers, such as colon (13%-25%), gynecological (12%-23%), and lymphoma (8%-19%). This report reviews the prevalence of depression in cancer patients throughout the course of cancer.

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Authors
Massie, M. J.
Affiliations
Memorial Sloan Kettering Cancer Center (US)
Corresponding author
Massie, M. J.
Venue
Journal of the National Cancer Institute Monographs
Publisher
Oxford University Press (OUP)
Published
2004-07-01
Volume
2004
Issue
32
Pages
57-71
ISSN
1052-6773 (ISSN-L)
DOI
10.1093/jncimonographs/lgh014
OpenAlex
W2111457041
Cited by
1,408
References
117
Citations by year
2026: 34 · 2025: 33 · 2024: 35 · 2023: 62 · 2022: 102 · 2021: 74 · 2020: 65 · 2019: 79 · 2018: 62 · 2017: 63 · 2016: 82 · 2015: 76 · 2014: 81 · 2013: 119 · 2012: 104
FWCI
2.05
Type
journal article
Language
en
Open access
Locations
  • JNCI Monographs (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
Keywords
depression, cancer patients, prevalence, major depressive disorder, oropharyngeal cancer, pancreatic cancer, breast cancer, lung cancer, cancer-related depression, mood assessment
MeSH terms
Depressive Disorder, Fatigue, Humans, Neoplasms, Pain, Risk Factors, Sex Factors, Prevalence

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