Review: Genetics of Attention Deficit/Hyperactivity Disorder

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Attention-deficit hyperactivity disorder

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Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder

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Multiple dopamine D4 receptor variants in the human population

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Further Evidence for Family-Genetic Risk Factors in Attention Deficit Hyperactivity Disorder: Patterns of Comorbidity in Probands and Relatives in Psychiatrically and Pediatrically Referred Samples

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Meta-analysis of the association between the 7-repeat allele of the dopamine D(4) receptor gene and attention deficit hyperactivity disorder.

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Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder.

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National Institute of Mental Health Multimodal Treatment Study of ADHD Follow-up: 24-Month Outcomes of Treatment Strategies for Attention-Deficit/Hyperactivity Disorder

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Environmental risk factors for attention‐deficit hyperactivity disorder

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The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

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Comorbidity of Reading Disability and Attention-Deficit/ Hyperactivity Disorder

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Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography

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Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism.

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Association and linkage of the dopamine transporter gene and attention-deficit hyperactivity disorder in children: Heterogeneity owing to diagnostic subtype and severity

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Dopamine genes and ADHD

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Dopamine D4 Receptor-Knock-Out Mice Exhibit Reduced Exploration of Novel Stimuli

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Gender differences in a sample of adults with attention deficit hyperactivity disorder.

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A genomewide scan for loci involved in attention-deficit/hyperactivity disorder.

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A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy.

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Adoptive and Biological Families of Children and Adolescents With ADHD

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Role of dopamine transporter genotype and maternal prenatal smoking in childhood hyperactive-impulsive, inattentive, and oppositional behaviors

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Symptomatic Improvement in Children With ADHD Treated With Long-Term Methylphenidate and Multimodal Psychosocial Treatment

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Impact of comorbidity in adults with attention-deficit/hyperactivity disorder.

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Prenatal smoking exposure and dopaminergic genotypes interact to cause a severe ADHD subtype

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Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention

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A Whole-Genome Scan in 164 Dutch Sib Pairs with Attention-Deficit/Hyperactivity Disorder: Suggestive Evidence for Linkage on Chromosomes 7p and 15q

Bakker, S. C., Meulen, E. M. V. D., Buitelaar, J. K., Sandkuijl, L. A., Pauls, D. L., Monsuur, A. J., Slot, R. V. ‘., Minderaa, R. B., Gunning, W. B., Pearson, P. L., et al. (2003) · The American Journal of Human Genetics · doi:10.1086/375143 · Cited by 257 · see citing works

Separation of DSM-III attention deficit disorder and conduct disorder: evidence from a family-genetic study of American child psychiatric patients

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Support for association between ADHD and two candidate genes: NET1 and DRD1

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Identification of DNA variants in the SNAP-25 gene and linkage study of these polymorphisms and attention-deficit hyperactivity disorder

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A Genomewide Scan for Attention-Deficit/Hyperactivity Disorder in an Extended Sample: Suggestive Linkage on 17p11

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Association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and childhood ADHD psychopathology

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Attention-Deficit/Hyperactivity Disorder in a Population Isolate: Linkage to Loci at 4q13.2, 5q33.3, 11q22, and 17p11

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Catechol O-Methyltransferase Gene Variant and Birth Weight Predict Early-Onset Antisocial Behavior in Children With Attention-Deficit/Hyperactivity Disorder

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Toward guidelines for pedigree selection in genetic studies of attention deficit hyperactivity disorder

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Molecular genetic studies of ADHD: 1991 to 2004

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Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sample.

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Prevalence of Attention-Deficit/Hyperactivity Disorder Symptoms in 4- to 17-Year-Old Children in the General Population

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Attention-Deficit Hyperactivity Disorder in Girls

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Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT1B receptor gene in 273 nuclear families from a multi-centre sample

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Conduct problems, gender and adult psychiatric outcome of children with attention-deficit hyperactivity disorder

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Synaptosomal-associated protein 25 (SNAP-25) and attention deficit hyperactivity disorder (ADHD): evidence of linkage and association in the Irish population

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Additive Effects of Psychostimulants, Parent Training, and Self-Control Therapy with ADHD Children

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Familiality and Heritability of Subtypes of Attention Deficit Hyperactivity Disorder in a Population Sample of Adolescent Female Twins

Todd, R. D., Rasmussen, E. R., Neuman, R. J., Reich, W., Hudziak, J. J., Bucholz, K. K., Madden, P. A. F., & Heath, A. C. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1891 · Cited by 164 · see citing works

Multivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder

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A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs

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Attention deficit disorder and conduct disorder: longitudinal evidence for a familial subtype

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A family-genetic study of girls with DSM-III attention deficit disorder

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Segregation analysis of attention deficit hyperactivity disorder

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A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: Interaction with adverse childhood environment

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Further Evidence for Family-Genetic Risk Factors in Attention Deficit Hyperactivity Disorder

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5-HT2 Receptor Antagonism Reduces Hyperactivity Induced by Amphetamine, Cocaine, and MK-801 But Not D1 Agonist C-APB

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Attention deficit hyperactivity disorder: fine mapping supports linkage to 5p13, 6q12, 16p13, and 17p11

Ogdie, M. N., Fisher, S. E., Yang, M., Ishii, J., Francks, C., Loo, S. K., Cantor, R. M., McCracken, J. T., McGough, J. J., Smalley, S. L., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/424387 · Cited by 133 · see citing works

A family study of patients with attention deficit disorder and normal controls

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Latent class analysis of ADHD and comorbid symptoms in a population sample of adolescent female twins

Neuman, R. J., Heath, A., Reich, W., Bucholz, K. K., Madden, P. A. F., Sun, L., Todd, R. D., & Hudziak, J. J. (2001) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00789 · Cited by 125 · see citing works

Functional polymorphism within the promotor of the serotonin transporter gene is associated with severe hyperkinetic disorders

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Biased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder

Kustanovich, V., Merriman, B., McGough, J., McCracken, J. T., Smalley, S. L., & Nelson, S. F. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001247 · Cited by 122 · see citing works

Evidence for the serotonin HTR2A receptor gene as a susceptibility factor in attention deficit hyperactivity disorder (ADHD)

Quist, J., Barr, C., Schachar, R., Roberts, W., Malone, M., Tannock, R., Basile, V., Beitchman, J., & Kennedy, J. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000779 · Cited by 121 · see citing works

Mutational analysis of the nicotinic acetylcholine receptor alpha 4 subunit gene in attention deficit/hyperactivity disorder: evidence for association of an intronic polymorphism with attention problems

Todd, R. D., Lobos, E. A., Sun, L.-W., & Neuman, R. J. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001257 · Cited by 115 · see citing works

Familial clustering of latent class and DSM‐IV defined attention‐deficit/hyperactivity disorder (ADHD) subtypes

Rasmussen, E., Neuman, R. J., Heath, A. C., Lévy, F., Hay, D. A., & Todd, R. D. (2004) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2004.00248.x · Cited by 114 · see citing works

Family‐based and case‐control association studies of catechol‐<i>O</i>‐methyltransferase in attention deficit hyperactivity disorder suggest genetic sexual dimorphism

Qian, Q., Wang, Y., Zhou, R., Li, J., Wang, B., Glatt, S., & Faraone, S. V. (2003) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.10064 · Cited by 113 · see citing works

Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP‐25, and 5HT1B

Mill, J., Xu, X.-H., Ronald, A., Curran, S., Price, T., Knight, J., Craig, I., Sham, P., Plomin, R., & Asherson, P. (2005) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30107 · Cited by 109 · see citing works

Significance of Serotonin Transporter Gene 5-HTTLPR and Variable Number of Tandem Repeat Polymorphism in Attention Deficit Hyperactivity Disorder

Zoroglu, S., Erdal, M., Alaşehirli, B., Erdal, N., Si̇vasli, E., Tutkun, H., Savaş, H., & Herken, H. (2002) · Neuropsychobiology · doi:10.1159/000063667 · Cited by 108 · see citing works

Haplotype analysis of SNAP-25 suggests a role in the aetiology of ADHD

Mill, J., Richards, S., Knight, J., Curran, S., Taylor, E., & Asherson, P. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001482 · Cited by 108 · see citing works

A high-density single-nucleotide polymorphism screen of 23 candidate genes in attention deficit hyperactivity disorder: suggesting multiple susceptibility genes among Chinese Han population

Guan, L., Wang, B., Chen, Y., Yang, L., Li, J., Qian, Q., Wang, Z., Faraone, S. V., & Wang, Y.-T. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002139 · Cited by 105 · see citing works

Replication of the latent class structure of Attention‐Deficit/Hyperactivity Disorder (ADHD) subtypes in a sample of Australian twins

Rasmussen, E. R., Neuman, R. J., Heath, A. C., Lévy, F., Hay, D. A., & Todd, R. D. (2002) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00229 · Cited by 105 · see citing works

The SNAP25 gene as a susceptibility gene contributing to attention-deficit hyperactivity disorder

Feng, Y., Crosbie, J., Wigg, K., Pathare, T., Ickowicz, A., Schachar, R. J., Tannock, R., Roberts, W., MALONE, M. A., Swanson, J. M., et al. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001722 · Cited by 101 · see citing works

Gene–Environment interactions in the development of combined type ADHD: Evidence for a synapse-based model

Todd, R. D., & Neuman, R. J. (2007) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30640 · Cited by 99 · see citing works

Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families

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Association study of a SNAP-25 microsatellite and attention deficit hyperactivity disorder.

Mill, J., Curran, S., Kent, L., Gould, A., Huckett, L., Richards, S., Taylor, E., & Asherson, P. (2002) · American journal of medical genetics · doi:10.1002/ajmg.10253 · Cited by 94 · see citing works

The norepinephrine transporter gene and attention-deficit hyperactivity disorder.

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Factor and Latent Class Analysis of DSM-IV ADHD Symptoms in a School Sample of Brazilian Adolescents

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