Negative Symptoms in Schizophrenia: Avolition and Occam's Razor

Foussias, G.; Remington, G.

doi:10.1093/schbul/sbn094

Cited by 594Schizophrenia research and treatmentMental Health and PsychiatryMental Health Research Topics

Negative Symptoms in Schizophrenia: Avolition and Occam's Razor

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Foussias, G., Remington, G.·2010·Schizophrenia Bulletin

DOI 10.1093/schbul/sbn094PMC PMC2833114

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Abstract

The identification of schizophrenia's negative symptoms dates back to the earliest descriptions of Kraepelin and Bleuler, who each highlighted the central role of avolition in the phenomenology and course of this illness. Since, there have been numerous advances in our understanding of schizophrenia, and the present review tracks the changes that have taken place in our understanding of negative symptoms, their description and measurement. That these symptoms represent a distinct domain of the illness is discussed in the context of their ties to other symptoms and functional outcome. The underlying structure of the negative symptom construct is explored, including several lines of investigation that point towards diminished expression and amotivation as key underlying subdomains. We also discuss findings of intact emotional experience and consummatory pleasure in individuals with schizophrenia, calling into question the presence of anhedonia in this illness. We conclude with a reconceptualization of the negative symptoms, suggesting amotivation (ie, avolition) represents the critical component, particularly in regard to functional outcome. Further exploration and clarification of this core deficit will ultimately enhance our neurobiological understanding of schizophrenia, as well as strategies that may improve outcome.

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Anhedonia (diminished 'liking') is a less prominent feature of schizophrenia than avolition (diminished 'wanting').
“Several authoritative reviews thus concluded that anhedonia (diminished ‘liking’) is a less prominent feature of schizophrenia than avolition (diminished ‘wanting’) [49,51-53].”
From Social “wanting” dysfunction in autism: neurobiological underpinnings and treatment implications (2012) · cites this paper as [49]

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Authors: Foussias, G., & Remington, G.
Affiliations: Centre for Addiction and Mental Health (CA)
Corresponding author: Foussias, G.
ORCID: Foussias, G.
Remington, G.
Venue: Schizophrenia Bulletin
Publisher: Oxford University Press (OUP)
Published: 2008-07-21
Volume: 36
Issue: 2
Pages: 359-369
ISSN: 0586-7614 (ISSN-L)
1745-1701
DOI: 10.1093/schbul/sbn094
PMC: PMC2833114
OpenAlex: W2156770514
Cited by: 594
References: 91
Citations by year: 2026: 23 · 2025: 22 · 2024: 15 · 2023: 27 · 2022: 40 · 2021: 37 · 2020: 36 · 2019: 30 · 2018: 50 · 2017: 39 · 2016: 54 · 2015: 41 · 2014: 55 · 2013: 53 · 2012: 27
FWCI: 10.31
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Schizophrenia Bulletin (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Keywords: schizophrenia, negative symptoms
MeSH terms: Affective Symptoms, Drive, Emotions, Humans, Motivation, Prognosis, Psychiatric Status Rating Scales, Psychometrics, Schizophrenia, Schizophrenic Psychology, Social Isolation, Reproducibility of Results, Pleasure

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Negative Symptoms in Schizophrenia: Avolition and Occam's Razor

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