DNA Base Damage by Reactive Oxygen Species, Oxidizing Agents, and UV Radiation

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

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The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

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Reconciling the chemistry and biology of reactive oxygen species

Winterbourn, C. C. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.85 · Cited by 2,504

Hollow Capsule Processing through Colloidal Templating and Self-Assembly

Caruso, F. (2000) · Chemistry - A European Journal · doi:10.1002/(sici)1521-3765(20000204)6:3 · Cited by 883

Free-Radical-Induced DNA Damage and Its Repair

von Sonntag, C. (2006) · Springer eBooks · doi:10.1007/3-540-30592-0 · Cited by 811

Mutations induced by ultraviolet light

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Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

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Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidationPreprint

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Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation

Mouret, S., Baudouin, C., Charveron, M., Favier, A., Cadet, J., & Douki, T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604213103 · Cited by 684

Wavelength dependence of oxidative DNA damage induced by UV and visible light

Kielbassa, C. (1997) · Carcinogenesis · doi:10.1093/carcin/18.4.811 · Cited by 616

Oxidatively generated base damage to cellular DNA

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Oxidatively Generated Damage to the Guanine Moiety of DNA: Mechanistic Aspects and Formation in Cells

Cadet, J., Douki, T., & Ravanat, J.-L. (2008) · Accounts of Chemical Research · doi:10.1021/ar700245e · Cited by 555

Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products

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The Discovery of 5‐Formylcytosine in Embryonic Stem Cell DNA

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Bipyrimidine Photoproducts Rather than Oxidative Lesions Are the Main Type of DNA Damage Involved in the Genotoxic Effect of Solar UVA Radiation

Douki, T., Reynaud-Angelin, A., Cadet, J., & Sage, E. (2003) · Biochemistry · doi:10.1021/bi034593c · Cited by 452

5-Hydroxymethylcytosine Is Strongly Depleted in Human Cancers but Its Levels Do Not Correlate with IDH1 Mutations

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Myeloperoxidase: a target for new drug development?

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Quantification of the Sixth DNA Base Hydroxymethylcytosine in the Brain

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Individual Determination of the Yield of the Main UV-Induced Dimeric Pyrimidine Photoproducts in DNA Suggests a High Mutagenicity of CC Photolesions

Douki, T., & Cadet, J. (2001) · Biochemistry · doi:10.1021/bi0022543 · Cited by 337

2,2-Diamino-4-[(3,5-di-O-acetyl-2-deoxy-.beta.-D-erythro- pentofuranosyl)amino]-5-(2H)-oxazolone: a Novel and Predominant Radical Oxidation Product of 3',5'-Di-O-acetyl-2'-deoxyguanosine

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Singlet Oxygen Induces Oxidation of Cellular DNA

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Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA

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Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions†

Cadet, J., Mouret, S., Ravanat, J., & Douki, T. (2012) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2012.01200.x · Cited by 300

NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).cntdot.dA(anti) alignment at lesion site

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New functions of XPC in the protection of human skin cells from oxidative damage

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High-performance liquid chromatography--tandem mass spectrometry measurement of radiation-induced base damage to isolated and cellular DNA

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Endogenous oxidative damage of deoxycytidine in DNA.

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5‐Hydroxymethylcytosine, the Sixth Base of the Genome

Münzel, M., Globisch, D., & Carell, T. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201101547 · Cited by 252

Formation of the Main UV-induced Thymine Dimeric Lesions within Isolated and Cellular DNA as Measured by High Performance Liquid Chromatography-Tandem Mass Spectrometry

Douki, T., Court, M., Sauvaigo, S., Odin, F., & Cadet, J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.16.11678 · Cited by 239

Oxidatively generated complex DNA damage: Tandem and clustered lesions

Cadet, J., Ravanat, J.-L., TavernaPorro, M., Menoni, H., & Angelov, D. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.04.005 · Cited by 233

Measurement and Meaning of Oxidatively Modified DNA Lesions in Urine

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Oxidative DNA Damage Associated with Combination of Guanine and Superoxide Radicals and Repair Mechanisms via Radical Trapping

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Formation of Modified DNA Bases in Cells Exposed either to Gamma Radiation or to High-LET Particles1

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NMR studies of a DNA containing 8-hydroxydeoxyguanosine

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The Chemical Toxicology of 2-Deoxyribose Oxidation in DNA

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Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation

Cadet, J., Douki, T., Ravanat, J.-L., & Di Mascio, P. (2009) · Photochemical & Photobiological Sciences · doi:10.1039/b905343n · Cited by 213

Hypochlorite-Induced Damage to DNA, RNA, and Polynucleotides: Formation of Chloramines and Nitrogen-Centered Radicals

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The carbonate radical and related oxidants derived from bicarbonate buffer

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DNA oxidation: Investigating its key role in environmental mutagenesis with the comet assay

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Oxidation Reactions of Cytosine DNA Components by Hydroxyl Radical and One-Electron Oxidants in Aerated Aqueous Solutions

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Guanine Oxidation: One‐ and Two‐Electron Reactions

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Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion

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Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations

Courdavault, S., Baudouin, C., Charveron, M., Canguilhem, B., Favier, A., Cadet, J., & Douki, T. (2005) · DNA Repair · doi:10.1016/j.dnarep.2005.05.001 · Cited by 156

Structural and conformational analyses of 8-hydroxy-2'-deoxyguanosine

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UVA-induced cyclobutane pyrimidine dimers in DNA: a direct photochemical mechanism?

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Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids

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Low values of 5‐hydroxymethylcytosine (5hmC), the “sixth base,” are associated with anaplasia in human brain tumors

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Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

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Chlorination of Guanosine and Other Nucleosides by Hypochlorous Acid and Myeloperoxidase of Activated Human Neutrophils

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The oxidative DNA lesions 8,5′-cyclopurines accumulate with aging in a tissue-specific manner

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Characterization of Lysine−Guanine Cross-Links upon One-Electron Oxidation of a Guanine-Containing Oligonucleotide in the Presence of a Trilysine Peptide

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UVA1 induces cyclobutane pyrimidine dimers but not 6-4 photoproducts in human skin in vivo

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Pattern of hydroxy radical reaction with adenine and its nucleosides and nucleotides. Characterization of two types of isomeric hydroxy adduct and their unimolecular transformation reactions

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HO • radicals induce an unexpected high proportion of tandem base lesions refractory to repair by DNA glycosylases

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Purine 5′,8-cyclonucleoside lesions: chemistry and biology

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The role of CSA in the response to oxidative DNA damage in human cells

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Measurement of oxidatively generated base damage in cellular DNA

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Oxidation of Guanine in Cellular DNA by Solar UV Radiation: Biological Role†

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Oxidatively generated damage to DNA by UVA radiation in cells and human skin

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Endoperoxide formation in a guanosine derivative

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Quantification of Oxidative DNA Lesions in Tissues of Long-Evans Cinnamon Rats by Capillary High-Performance Liquid Chromatography−Tandem Mass Spectrometry Coupled with Stable Isotope-Dilution Method

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Characterization and Chemical Stability of Photooxidized Oligonucleotides that Contain 2,2-Diamino-4-[(2-deoxy-β- d -erythro-pentofuranosyl)amino]-5(2H)-oxazolone

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Tandem Base Lesions Are Generated by Hydroxyl Radical within Isolated DNA in Aerated Aqueous Solution

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Base Pairing Enhances Fluorescence and Favors Cyclobutane Dimer Formation Induced upon Absorption of UVA Radiation by DNA

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Minor contribution of direct ionization to DNA base damage inducedby heavy ions

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Glutathione and ascorbate are negatively correlated with oxidative DNA damage in human lymphocytes

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Thymidine Hydroperoxides: Structural Assignment, Conformational Features, and Thermal Decomposition in Water

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UV Laser Photolysis of DNA: Effect of Duplex Stability on Charge-Transfer Efficiency

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Quantitative analysis of the oxidative DNA lesion, 2,2-diamino-4-(2-deoxy-β-d-erythro-pentofuranosyl)amino]-5(2H)-oxazolone (oxazolone), in vitro and in vivo by isotope dilution-capillary HPLC-ESI-MS/MS

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Radiation-induced formation of purine 5′,8-cyclonucleosides in isolated and cellular DNA: high stereospecificity and modulating effect of oxygen

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The specificity of UVA-induced DNA damage in human melanocytes

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Hypochlorite-Induced Damage to Nucleosides: Formation of Chloramines and Nitrogen-Centered Radicals

Hawkins, C. L., & Davies, M. J. (2001) · Chemical Research in Toxicology · doi:10.1021/tx010071r · Cited by 94

Mechanism of DNA damage induced by bromate differs from general types of oxidative stress

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Differential repair of UVB-induced cyclobutane pyrimidine dimers in cultured human skin cells and whole human skin

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DNA Tandem Lesions Containing 8-Oxo-7,8-dihydroguanine and Formamido Residues Arise from Intramolecular Addition of Thymine Peroxyl Radical to Guanine

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The Discovery of 5‐Formylcytosine in Embryonic Stem Cell DNA

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Photosensitized Oxidation of 5-Methyl-2‘-deoxycytidine by 2-Methyl-1,4-naphthoquinone: Characterization of 5-(Hydroperoxymethyl)-2‘-deoxycytidine and Stable Methyl Group Oxidation Products

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Singlet oxygen-mediated damage to cellular DNA determined by the comet assay associated with DNA repair enzymes

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Characterization and Mechanism of Formation of Tandem Lesions in DNA by a Nucleobase Peroxyl Radical

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An ab initio molecular orbital study on the characteristics of 8-hydroxyguanine

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The Insulated SolarFenton Hybrid Process: Fundamental Investigations

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Mechanism of UV‐Induced Formation of Dewar Lesions in DNA

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Multiple forms of DNA Damage Caused by UVA Photoactivation of DNA 6‐Thioguanine

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New Insights into the Reaction Paths of Hydroxyl Radicals with 2′-Deoxyguanosine

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Hydroxyl-Radical-Induced Decomposition of 2‘-Deoxycytidine in Aerated Aqueous Solutions

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Detection of chlorinated DNA and RNA nucleosides by HPLC coupled to tandem mass spectrometry as potential biomarkers of inflammation

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Isolation, Characterization, and Independent Synthesis of Guanine Oxidation Products

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Nitrogen-15 nuclear magnetic resonance studies on the tautomerism of 8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanosine, and other C8-substituted guanine nucleosides

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Scope and Mechanism of Interstrand Cross-Link Formation by the C4′-Oxidized Abasic Site

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In Vivo Formation and in Vitro Replication of a Guanine−Thymine Intrastrand Cross-Link Lesion

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Mechanisms of Oxidation of Guanine in DNA by Carbonate Radical Anion, a Decomposition Product of Nitrosoperoxycarbonate

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Chemical and Immunochemical Detection of 8-Halogenated Deoxyguanosines at Early Stage Inflammation

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2′-Deoxycytidine Glycols, a Missing Link in the Free Radical-mediated Oxidation of DNA

Tremblay, S., Douki, T., Cadet, J., & Wagner, J. R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.30.20833 · Cited by 60

Recommendations for Standardized Description of and Nomenclature Concerning Oxidatively Damaged Nucleobases in DNA

Cooke, M. S., Loft, S. H., Oliński, R., Evans, M. D., Białkowski, K., Wagner, J. R., Dedon, P. C., Möller, P., Greenberg, M. M., & Cadet, J. (2010) · Chemical Research in Toxicology · doi:10.1021/tx1000706 · Cited by 58

Effects of Duplex Stability on Charge-Transfer Efficiency within DNA

Douki, T., Ravanat, J., Angelov, D., Wagner, J. R., & Cadet, J. (2012) · Topics in current chemistry · doi:10.1007/b94409 · Cited by 57

Profiling Cytosine Oxidation in DNA by LC-MS/MS

Samson-Thibault, F., Madugundu, G. S., Gao, S., Cadet, J., & Wagner, J. R. (2012) · Chemical Research in Toxicology · doi:10.1021/tx300195f · Cited by 53

No formation of DNA double-strand breaks and no activation of recombination repair with UVA

Rizzo, J. L., Dunn, J., Rees, A., & Rünger, T. M. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.365 · Cited by 50

Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice

Trapp, C., Reite, K., Klungland, A., & Epe, B. (2007) · Oncogene · doi:10.1038/sj.onc.1210167 · Cited by 50

Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation

Brem, R., Daehn, I., & Karran, P. (2011) · DNA Repair · doi:10.1016/j.dnarep.2011.05.010 · Cited by 48

Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA

Gueranger, Q., Kia, A., Frith, D., & Karran, P. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr112 · Cited by 47

Ionizing Radiation Causes Greater DNA Base Damage in Radiation-Sensitive Mutant M10 Cells Than in Parent Mouse Lymphoma L5178Y Cells

Mori, T., & Dizdaroğlu, M. (1994) · Radiation Research · doi:10.2307/3578572 · Cited by 47

Radical Oxidation of the Adenine Moiety of Nucleoside and DNA: 2-Hydroxy-2′-deoxyadenosine is a Minor Decomposition Product

Frelon, S., Douki, T., & Cadet, J. (2002) · Free Radical Research · doi:10.1080/10715760290025889 · Cited by 45

Individual Photosensitivity of Human Skin and UVA-Induced Pyrimidine Dimers in DNA

Mouret, S., Leccia, M. ‐., Bourrain, J. ‐., Douki, T., & Béani, J. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.47 · Cited by 44

Generation of Guanine–Thymidine Cross-Links in DNA by Peroxynitrite/Carbon Dioxide

Yun, B. H., Geacintov, N. E., & Shafirovich, V. (2011) · Chemical Research in Toxicology · doi:10.1021/tx200139c · Cited by 44

Ascorbate and H2O2 induced oxidative DNA damage in Jurkat cells

Rivière, J., Ravanat, J., & Wagner, J. R. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.02.003 · Cited by 43

Guanine–thymine intrastrand cross-linked lesion containing oligonucleotides: from chemical synthesis to in vitro enzymatic replication

Bellon, S., Gasparutto, D., Saint‐Pierre, C., & Cadet, J. (2006) · Organic & Biomolecular Chemistry · doi:10.1039/b609460k · Cited by 43

Hydroxylation of the C-8 position of deoxyguanosine by reducing agents in the presence of oxygen.

Kasai, H., & Nishimura, S. (1983) · PubMed · Cited by 43

Singlet oxygen induces oxidation of cellular DNA.

Ravanat, J.-L., Di Mascio, P., Martinez, G. R., Medeiros, M. G., & Cadet, J. (2001) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)46360-6 · Cited by 42

Detection of new radiation‐induced DNA lesions by liquid chromatography coupled to tandem mass spectrometry

Regulus, P., Spessotto, S., Gateau, M., Cadet, J., Favier, A. E., & Ravanat, J. (2004) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.1612 · Cited by 42

Tautomeric equilibria in 8-oxopurines: Implications for mutagenicity

Venkateswarlu, D., & Leszczyński, J. (1998) · Journal of Computer-Aided Molecular Design · doi:10.1023/a:1008067110965 · Cited by 41

Vicinal Lesions in X-irradiated DNA?

Box, H. C., Budzinski, E. E., Freund, H. G., Evans, M. S., Patrzyc, H. B., Wallace, J. C., & Maccubbin, A. E. (1993) · International Journal of Radiation Biology · doi:10.1080/09553009314551411 · Cited by 41

Site-specific radical formation in DNA induced by Cu(II)–H2O2 oxidizing system, using ESR, immuno-spin trapping, LC-MS, and MS/MS

Bhattacharjee, S., Deterding, L. J., Chatterjee, S., Jiang, J., Ehrenshaft, M., Lardinois, O. M., Ramírez, D. C., Tomer, K. B., & Mason, R. P. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.02.034 · Cited by 40

Measurement of oxidatively generated base damage to nucleic acids in cells: facts and artifacts

Cadet, J., Douki, T., Ravanat, J.-L., & Wagner, J. R. (2012) · Bioanalytical Reviews · doi:10.1007/s12566-012-0029-6 · Cited by 38

Measurement of (5′R)- and (5′S)-8,5′-cyclo-2′-deoxyadenosines in DNA in vivo by liquid chromatography/isotope-dilution tandem mass spectrometry

Jaruga, P., Xiao, Y., Nelson, B. C., & Dizdaroğlu, M. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.06.107 · Cited by 38

Invited Review A Compilation of Physical, Spectroscopic and Photophysical Properties of Polycyclic Aromatic Hydrocarbons

Dabestani, R., & Ivanov, I. N. (1999) · Photochemistry and Photobiology · doi:10.1562/0031-8655(1999)070 · Cited by 38

It’s All about Position: The Basal Layer of Human Epidermis Is Particularly Susceptible to Different Types of Sunlight-Induced DNA Damage

Halliday, G. M., & Cadet, J. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.281 · Cited by 35

Dehydration, deamination and enzymatic repair of cytosine glycols from oxidized poly(dG-dC) and poly(dI-dC)

Tremblay, S., & Wagner, J. R. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm1013 · Cited by 35

Oxidation of 5-Hydroxy-2‘-deoxyuridine into Isodialuric Acid, Dialuric Acid, and Hydantoin Products

Rivière, J., Bergeron, F., Tremblay, S., Gasparutto, D., Cadet, J., & Wagner, J. R. (2004) · Journal of the American Chemical Society · doi:10.1021/ja049438f · Cited by 34

Generation of 2′-Deoxyadenosine N6-Aminyl Radicals from the Photolysis of Phenylhydrazone Derivatives

Kuttappan-Nair, V., Samson-Thibault, F., & Wagner, J. R. (2009) · Chemical Research in Toxicology · doi:10.1021/tx900268r · Cited by 31

Structural, energetic and dynamic properties of guanine(C8)–thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair

Ding, S., Kropachev, K. Y., Cai, Y., Kolbanovskiy, M., Durandina, S. A., Liu, Z., Shafirovich, V., Broyde, S. B., & Geacintov, N. E. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr1087 · Cited by 28

High-resolution crystal structure of the intramolecular d(TpA) thymine-adenine photoadduct and its mechanistic implications

Davies, R. J. H., Malone, J. F., Gan, Y., Cardin, C. J., Lee, M. P., & Neidle, S. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkl1101 · Cited by 27

A New Photoproduct of 5-Methylcytosine and Adenine Characterized by High-Performance Liquid Chromatography and Mass Spectrometry

Su, D. G. T., Taylor, J.-S. A., & Gross, M. L. (2010) · Chemical Research in Toxicology · doi:10.1021/tx9003962 · Cited by 26

Isolation and Mass Spectrometric Characterization of Dimeric Adenine Photoproducts in Oligodeoxynucleotides

Wang, Y., Taylor, J., & Gross, M. L. (2001) · Chemical Research in Toxicology · doi:10.1021/tx010009u · Cited by 26

Kinetics of deamination and Cu(II)/H 2 O 2 /Ascorbate-induced formation of 5-methylcytosine glycol at CpG sites in duplex DNA

Cao, H., Jiang, Y., & Wang, Y. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp615 · Cited by 26

Surviving an Oxygen Atmosphere: DNA Damage and Repair

Burrows, C. J. (2009) · ACS symposium series · doi:10.1021/bk-2009-1025.ch008 · Cited by 25

Detection and imaging of the free radical DNA in cells--Site-specific radical formation induced by Fenton chemistry and its repair in cellular DNA as seen by electron spin resonance, immuno-spin trapping and confocal microscopy

Bhattacharjee, S., Chatterjee, S., Jiang, J., Sinha, B. K., & Mason, R. P. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks180 · Cited by 24

Oxidation of 5-Hydroxypyrimidine Nucleosides to 5-Hydroxyhydantoin and Its α-Hydroxy-ketone Isomer

Rivière, J., Klarskov, K., & Wagner, J. R. (2005) · Chemical Research in Toxicology · doi:10.1021/tx050121i · Cited by 23

Formation of 2′-deoxyuridine hydrates upon exposure of nucleosides to gamma radiation and UVC-irradiation of isolated and cellular DNA

Douki, T., Vadesne-Bauer, G., & Cadet, J. (2002) · Photochemical & Photobiological Sciences · doi:10.1039/b201612e · Cited by 22

UV-Induced TA Photoproducts: Formation and Hydrolysis in Double-Stranded DNA

Asgatay, S., Martinez, A., Coantic-Castex, S., Harakat, D., Philippe, C., Douki, T., & Clivio, P. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1023173 · Cited by 21

8-Hydroxyguanine: A base for discovery

Nishimura, S. (2011) · DNA repair · doi:10.1016/j.dnarep.2011.04.006 · Cited by 20

Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides

Sczepanski, J. T., Hiemstra, C. N., & Greenberg, M. M. (2011) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2011.08.024 · Cited by 20

Oxidation of 2‘-Deoxycytidine to Four Interconverting Diastereomers of N1-Carbamoyl-4,5-dihydroxy-2-oxoimidazolidine Nucleosides

Tremblay, S., Gantchev, T. G., Tremblay, L., Lavigne, P., Cadet, J., & Wagner, J. R. (2007) · The Journal of Organic Chemistry · doi:10.1021/jo062386n · Cited by 14

Unrepaired Cyclobutane Pyrimidine Dimers Do Not Prevent Proliferation of UV‐B‐irradiated Cultured Human Fibroblasts¶

Courdavault, S., Baudouin, C., Sauvaigo, S., Mouret, S., Candéias, S., Charveron, M., Favier, A., Cadet, J., & Douki, T. (2004) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2004.tb00004.x · Cited by 12

Oxidatively Generated Nucleobase Modifications in Isolated and Cellular DNA

Cadet, J., Douki, T., Gasparutto, D., Ravanat, J., & Wagner, J. R. (2012) · Wiley eBooks · doi:10.1002/9781119953678.rad038 · Cited by 7

Chlorination of guanosine and other nucleosides by hypochlorous acid and myeloperoxidase of activated human neutrophils : Catalysis by nicotine and trimethylamine

増田, 光. (2002) · Medical Entomology and Zoology · Cited by 6

Measurement of oxidatively generated base damage to nucleic acids in cells: facts and artifacts

Cadet, J., Douki, T., Ravanat, J., & Wagner, J. R. (2013) · Springer eBooks · doi:10.1007/978-3-642-36303-0_13 · Cited by 3

Unrepaired Cyclobutane Pyrimidine Dimers Do Not Prevent Proliferation of UV-B–irradiated Cultured Human Fibroblasts

Courdavault, S., Baudouin, C., Sauvaigo, S., et al. (2004) · BioOne Complete (BioOne) · doi:10.1562/0031-8655(2004)079<0145:ucpddn>2.0.co;2 · Cited by 3

Guanine Oxidation: One‐ and Two‐Electron Reactions

Pratviel, G., & Meunier, B. (2006) · ChemInform · doi:10.1002/chin.200647248 · Cited by 2

Isolation, Characterization, and Independent Synthesis of Guanine Oxidation Products

Gimisis, T., & Cismaş, C. (2006) · ChemInform · doi:10.1002/chin.200624238 · Cited by 1

Lifestyle, oxidative stress, and antioxidants: Back and forth in the pathophysiology of chronic diseases

Sharifi-Rad, M., Anil Kumar, N. V., Zucca, P., Varoni, E. M., Dini, L., Panzarini, E., Rajkovic, J., Tsouh Fokou, P. V., Azzini, E., Peluso, I., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00694 · Cited by 1,971

Arsenic Uptake, Toxicity, Detoxification, and Speciation in Plants: Physiological, Biochemical, and Molecular Aspects

Abbas, G., Murtaza, B., Bibi, I., Shahid, M. A. R., Niazi, N. K., Khan, M. I., Amjad, M., Hussain, M., & Natasha, N. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15010059 · Cited by 918

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Cimmino, L., Dolgalev, I., Wang, Y., Yoshimi, A., Martin, G. H., Wang, J., Ng, V., Xia, B., Witkowski, M. T., Mitchell-Flack, M., et al. (2017) · Cell · doi:10.1016/j.cell.2017.07.032 · Cited by 707

Modulating ROS to overcome multidrug resistance in cancer

Cui, Q., Wang, J., Assaraf, Y. G., Ren, L., Gupta, P., Wei, L., Ashby, C. R., Yang, D., & Chen, Z. (2018) · Drug Resistance Updates · doi:10.1016/j.drup.2018.11.001 · Cited by 677

Singlet Molecular Oxygen Reactions with Nucleic Acids, Lipids, and Proteins

Mascio, P. D., Martinez, G. R., Miyamoto, S., Ronsein, G. E., de Medeiros, M. H. G., & Cadet, J. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00554 · Cited by 674

Oxidatively generated base damage to cellular DNA

Cadet, J., Douki, T., & Ravanat, J. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.03.025 · Cited by 566

Oxidative degradation pathways of cellular DNA: product formation and mechanistic insights

Cadet, J. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.10.598 · Cited by 17

Oxidatively Generated Nucleobase Modifications in Isolated and Cellular DNA

Cadet, J., Douki, T., Gasparutto, D., Ravanat, J., & Wagner, J. R. (2012) · Wiley eBooks · doi:10.1002/9781119953678.rad038 · Cited by 7

Oxidatively generated base damage to cellular DNA by hydroxyl radical and one-electron oxidants: similarities and differences

Cadet, J., & Wagner, J. R. (2014) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2014.05.001 · Cited by 169

Oxidatively Generated Damage to the Guanine Moiety of DNA: Mechanistic Aspects and Formation in Cells

Cadet, J., Douki, T., & Ravanat, J.-L. (2008) · Accounts of Chemical Research · doi:10.1021/ar700245e · Cited by 555