Energy Efficient Low-Noise Neural Recording Amplifier With Enhanced Noise Efficiency Factor

Majidzadeh, Vahid; Schmid, Alexandre; Leblebici, Yusuf

doi:10.1109/tbcas.2010.2078815

Cited by 165Analog and Mixed-Signal Circuit DesignNeuroscience and Neural EngineeringRadio Frequency Integrated Circuit Design

Energy Efficient Low-Noise Neural Recording Amplifier With Enhanced Noise Efficiency Factor

Open access

Majidzadeh, Vahid, Schmid, Alexandre, Leblebici, Yusuf·2011·IEEE Transactions on Biomedical Circuits and Systems

DOI 10.1109/tbcas.2010.2078815

Open this paper in CoChat — free account

Abstract

This paper presents a neural recording amplifier array suitable for large-scale integration with multielectrode arrays in very low-power microelectronic cortical implants. The proposed amplifier is one of the most energy-efficient structures reported to date, which theoretically achieves an effective noise efficiency factor (NEF) smaller than the limit that can be achieved by any existing amplifier topology, which utilizes a differential pair input stage. The proposed architecture, which is referred to as a partial operational transconductance amplifier sharing architecture, results in a significant reduction of power dissipation as well as silicon area, in addition to the very low NEF. The effect of mismatch on crosstalk between channels and the tradeoff between noise and crosstalk are theoretically analyzed. Moreover, a mathematical model of the nonlinearity of the amplifier is derived, and its accuracy is confirmed by simulations and measurements. For an array of four neural amplifiers, measurement results show a midband gain of 39.4 dB and a -3-dB bandwidth ranging from 10 Hz to 7.2 kHz. The input-referred noise integrated from 10 Hz to 100 kHz is measured at 3.5 μVrms and the power consumption is 7.92 μW from a 1.8-V supply, which corresponds to NEF = 3.35. The worst-case crosstalk and common-mode rejection ratio within the desired bandwidth are - 43.5 dB and 70.1 dB, respectively, and the active silicon area of each amplifier is 256 μm × 256 μm in 0.18-μm complementary metal-oxide semiconductor technology.

Integrity signals

Registry

Crossref · 10.1109/tbcas.2010.2078815

Cites

16 of 16 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Majidzadeh et al. demonstrated sharing the reference branch of one front-end amplifier among multiple channels.
“A recent work by Majidzadeh et al. [78] demonstrated how to share the reference branch of one front-end amplifier among multiple channels.”
From Implantable neurotechnologies: a review of integrated circuit neural amplifiers (2016) · cites this paper as [78]
Recent studies have attempted to reduce silicon area by using smaller unit capacitors or by reducing amplifier gain.
“Recent studies have attempted to reduce the silicon area by using smaller unit capacitors or reducing the amplifier gain [77, 78].”
From Implantable neurotechnologies: a review of integrated circuit neural amplifiers (2016) · cites this paper as [78]

Circuit techniques for reducing the effects of op-amp imperfections: autozeroing, correlated double sampling, and chopper stabilization
Enz, C., & Temes, G. C. (1996) · Proceedings of the IEEE · doi:10.1109/5.542410 · Cited by 1,878 · see citing works
A low-power low-noise cmos for amplifier neural recording applications
Harrison, R. R., & Charles, C. (2003) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2003.811979 · Cited by 1,695 · see citing works
Real-time prediction of hand trajectory by ensembles of cortical neurons in primates
Wessberg, J., Stambaugh, C. R., Kralik, J. D., Beck, P. D., Laubach, M., Chapin, J. K., Kim, J., Biggs, S. J., Srinivasan, M. A., & Nicolelis, M. A. L. (2000) · Nature · doi:10.1038/35042582 · Cited by 1,491 · see citing works
A micropower low-noise monolithic instrumentation amplifier for medical purposes
Steyaert, M. S. J., & Sansen, W. M. C. (1987) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.1987.1052869 · Cited by 577 · see citing works
An Energy-Efficient Micropower Neural Recording Amplifier
Wattanapanitch, W., Fee, M., & Sarpeshkar, R. (2007) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2007.907868 · Cited by 441 · see citing works
Charge‐Based MOS Transistor Modeling
Enz, C., & Vittoz, E. A. (2006) · Wiley eBooks · doi:10.1002/0470855460 · Cited by 419 · see citing works
Single unit recording capabilities of a 100 microelectrode array
Nordhausen, C. T., Maynard, E. M., & Normann, R. A. (1996) · Brain Research · doi:10.1016/0006-8993(96)00321-6 · Cited by 358 · see citing works
Charge-Based MOS Transistor Modeling - The EKV Model for Low-Power and RF IC Design
Enz, C., & Vittoz, E. A. (2006) · Cited by 238 · see citing works
A Low-Power Integrated Bioamplifier With Active Low-Frequency Suppression
Gosselin, B. J., Sawan, M., & Chapman, C. A. (2007) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2007.914490 · Cited by 174 · see citing works
A Fully Integrated Neural Recording Amplifier With DC Input Stabilization
Mohseni, P., & Najafi, K. (2004) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2004.824126 · Cited by 173 · see citing works
Integrated circuit amplifiers for multi-electrode intracortical recording
Jochum, T., Denison, T., & Wolf, P. D. (2009) · Journal of Neural Engineering · doi:10.1088/1741-2560/6/1/012001 · Cited by 167 · see citing works
A Sub-Microwatt Low-Noise Amplifier for Neural Recording
Holleman, J. H., & Otis, B. P. (2007) · Conference proceedings · doi:10.1109/iembs.2007.4353193 · Cited by 111 · see citing works
Design of a CMOS Potentiostat Circuit for Electrochemical Detector Arrays
Ayers, S., Gillis, K. D., Lindau, M., & Minch, B. A. (2007) · IEEE Transactions on Circuits and Systems I Regular Papers · doi:10.1109/tcsi.2006.888777 · Cited by 109 · see citing works
A 500µW neural tag with 2µVrms AFE and frequency-multiplying MICS/ISM FSK transmitter
Rai, S., Holleman, J. H., Pandey, J., Zhang, F., & Otis, B. P. (2009) · Digest of technical papers/Digest of technical papers - IEEE International Solid-State Circuits Conference · doi:10.1109/isscc.2009.4977383 · Cited by 54 · see citing works
Numerical analysis of temperature elevation in the head due to power dissipation in a cortical implant
Silay, K. M., Dehollain, C., & Declercq, M. J. (2008) · doi:10.1109/iembs.2008.4649312 · Cited by 31 · see citing works
A micropower neural recording amplifier with improved noise efficiency factor
Majidzadeh, V., Schmid, A., & Leblebici, Y. (2009) · European Conference on Circuit Theory and Design · doi:10.1109/ecctd.2009.5274982 · Cited by 18 · see citing works
Self-citation

Flagged first, then by citations

Sorted by citations

A High Dynamic-Range Neural Recording Chopper Amplifier for Simultaneous Neural Recording and Stimulation
Chandrakumar, H., & Markovic, D. (2017) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2016.2645611 · Cited by 237 · see citing works
An 80-mVpp Linear-Input Range, 1.6-GΩ Input Impedance, Low-Power Chopper Amplifier for Closed-Loop Neural Recording That Is Tolerant to 650-mVpp Common-Mode Interference
Chandrakumar, H., & Markovic, D. M. (2017) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2017.2753824 · Cited by 187 · see citing works
A Low-Power, High CMRR Neural Amplifier System Employing CMOS Inverter-Based OTAs With CMFB Through Supply Rails
Ng, K. A., & Xu, Y. P. (2016) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2015.2512935 · Cited by 145 · see citing works
A 15.2-ENOB 5-kHz BW 4.5- $\mu$ W Chopped CT $\Delta\Sigma$ -ADC for Artifact-Tolerant Neural Recording Front Ends
Chandrakumar, H., & Markovic, D. M. (2018) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2018.2876468 · Cited by 135 · see citing works
Battery-less Tri-band-Radio Neuro-monitor and Responsive Neurostimulator for Diagnostics and Treatment of Neurological Disorders
Kassiri, H., Bagheri, A., Soltani, N., Abdelhalim, K., Jafari, H. M., Salam, M. T., Velázquez, J. L. P., & Genov, R. (2016) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2016.2528999 · Cited by 117 · see citing works
A Low-Noise Chopper Amplifier Designed for Multi-Channel Neural Signal Acquisition
Luo, D., Zhang, M., & Wang, Z. (2019) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2019.2913101 · Cited by 114 · see citing works
A Low-Power Programmable Neural Spike Detection Channel With Embedded Calibration and Data Compression
Rodriguez-Perez, A., Ruiz-Amaya, J., Delgado-Restituto, M., & Rodriguez-Vazquez, Á. (2012) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2012.2187352 · Cited by 103 · see citing works
Analysis and Design of Tunable Amplifiers for Implantable Neural Recording Applications
Rezaee-Dehsorkh, H., Ravanshad, N., Lotfi, R., Mafinezhad, K., & Sodagar, A. M. (2011) · IEEE Journal on Emerging and Selected Topics in Circuits and Systems · doi:10.1109/jetcas.2011.2174492 · Cited by 103 · see citing works
Compact Low-Power Cortical Recording Architecture for Compressive Multichannel Data Acquisition
Shoaran, M., Kamal, M. H., Pollo, C., Vandergheynst, P., & Schmid, A. (2014) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2014.2304582 · Cited by 101 · see citing works
Self-citation
A Fully Reconfigurable Low-Noise Biopotential Sensing Amplifier With 1.96 Noise Efficiency Factor
Wang, T.-Y., Lai, M.-R., Twigg, C. M., & Peng, S.-Y. (2013) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2013.2278659 · Cited by 97 · see citing works
Implantable neurotechnologies: a review of integrated circuit neural amplifiers
Ng, K. A., Greenwald, E., Xu, Y. P., & Thakor, N. V. (2016) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-015-1431-3 · Cited by 83 · see citing works
A Compact, Low Input Capacitance Neural Recording Amplifier
Ng, K. A., & Xu, Y. P. (2013) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2013.2280066 · Cited by 81 · see citing works
A 13.9-nA ECG Amplifier Achieving 0.86/0.99 NEF/PEF Using AC-Coupled OTA-Stacking
Mondal, S., & Hall, D. A. (2019) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2019.2957193 · Cited by 81 · see citing works
A 400 GΩ Input-Impedance Active Electrode for Non-Contact Capacitively Coupled ECG Acquisition With Large Linear-Input-Range and High CM-Interference-Tolerance
Chen, M., Chun, H. S., Castro, I. D., Torfs, T., Lin, Q., Hoof, C. A. V., Wang, G., Lian, Y., & Helleputte, N. V. (2019) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2019.2895660 · Cited by 80 · see citing works
An Orthogonal Current-Reuse Amplifier for Multi-Channel Sensing
Johnson, B., & Molnar, A. (2013) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2013.2257478 · Cited by 80 · see citing works
A Low-Power Current-Reuse Analog Front-End for High-Density Neural Recording Implants
Rezaei, M., Maghsoudloo, E., Bories, C., Koninck, Y. D., & Gosselin, B. J. (2018) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2018.2805278 · Cited by 67 · see citing works
A 0.09 $\mu$ W Low Power Front-End Biopotential Amplifier for Biosignal Recording
Tseng, Y., Ho, Y., Kao, S.-T., & Su, C. (2012) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2012.2188029 · Cited by 65 · see citing works
Energy Efficient Low-Noise Multichannel Neural Amplifier in Submicron CMOS Process
Kmon, P., & Gryboś, P. (2013) · IEEE Transactions on Circuits and Systems I Regular Papers · doi:10.1109/tcsi.2012.2230504 · Cited by 61 · see citing works
An Area-Efficient Noise-Adaptive Neural Amplifier in 130 nm CMOS Technology
Chaturvedi, V., & Amrutur, B. (2011) · IEEE Journal on Emerging and Selected Topics in Circuits and Systems · doi:10.1109/jetcas.2011.2178731 · Cited by 60 · see citing works
An Ultralow-Power Low-Noise CMOS Biopotential Amplifier for Neural Recording
Tan, Y., & Holleman, J. H. (2015) · IEEE Transactions on Circuits & Systems II Express Briefs · doi:10.1109/tcsii.2015.2457811 · Cited by 53 · see citing works
A 0.13- $\mu\text{m}$ CMOS SoC for Simultaneous Multichannel Optogenetics and Neural Recording
Gagnon-Turcotte, G., Khiarak, M. N., Éthier, C., Koninck, Y. D., & Gosselin, B. J. (2018) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2018.2865474 · Cited by 53 · see citing works
A Noise-Power-Area Optimized Biosensing Front End for Wireless Body Sensor Nodes and Medical Implantable Devices
Bhamra, H., Lynch, J., Ward, M. P., & Irazoqui, P. P. (2017) · IEEE Transactions on Very Large Scale Integration (VLSI) Systems · doi:10.1109/tvlsi.2017.2714171 · Cited by 52 · see citing works
A Survey of Neural Front End Amplifiers and Their Requirements toward Practical Neural Interfaces
Bharucha, E. A., Sepehrian, H., & Gosselin, B. J. (2014) · Journal of Low Power Electronics and Applications · doi:10.3390/jlpea4040268 · Cited by 49 · see citing works
A Digitally Assisted, Signal Folding Neural Recording Amplifier
Chen, Y., Basu, A., Liu, L., Zou, X., Rajkumar, R., Dawe, G. S., & Je, M. (2014) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2013.2288680 · Cited by 43 · see citing works
An Integrated Circuit for Simultaneous Extracellular Electrophysiology Recording and Optogenetic Neural Manipulation
Chen, C. H., McCullagh, E. A., Pun, S. H., Mak, P. U., Vai, M. I., Mak, P., Klug, A., & Lei, T. C. (2017) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2016.2609412 · Cited by 42 · see citing works
A Power-Efficient Highly Linear Reconfigurable Biopotential Sensing Amplifier Using Gate-Balanced Pseudoresistors
Wang, T.-Y., Liu, L., & Peng, S.-Y. (2015) · IEEE Transactions on Circuits & Systems II Express Briefs · doi:10.1109/tcsii.2014.2387685 · Cited by 35 · see citing works
A 15-Channel Orthogonal Code Chopping Instrumentation Amplifier for Area-Efficient, Low-Mismatch Bio-Signal Acquisition
Park, J. H., Tang, T., Zhang, L., Ng, K. A., Gammad, G. G. L., Yen, S., & Yoo, J. (2020) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2020.2991542 · Cited by 34 · see citing works
A 430nW 64nV/vHz current-reuse telescopic amplifier for neural recording applications
Song, S., Rooijakkers, M. J., Harpe, P., Rabotti, C., Mischi, M., van Roermund, A. H. M., & Cantatore, E. (2013) · 2013 IEEE Biomedical Circuits and Systems Conference (BioCAS) · doi:10.1109/biocas.2013.6679704 · Cited by 33 · see citing works
11.6 A multi-channel neural-recording amplifier system with 90dB CMRR employing CMOS-inverter-based OTAs with CMFB through supply rails in 65nm CMOS
Ng, K. A., & Xu, Y. P. (2015) · Digest of technical papers/Digest of technical papers - IEEE International Solid-State Circuits Conference · doi:10.1109/isscc.2015.7062998 · Cited by 33 · see citing works
Circuit and System Designs of Ultra-Low Power Sensor Nodes With Illustration in a Miniaturized GNSS Logger for Position Tracking: Part I—Analog Circuit Techniques
Jang, T., Kim, G., Kempke, B. P., Henry, M. B., Chiotellis, N., Pfeiffer, C., Kim, D., Kim, Y., Foo, Z., Kim, H., et al. (2017) · IEEE Transactions on Circuits and Systems I Regular Papers · doi:10.1109/tcsi.2017.2730600 · Cited by 33 · see citing works
Design considerations for effective neural signal sensing and amplification: a review
Sharma, K., & Sharma, R. (2019) · Biomedical Physics & Engineering Express · doi:10.1088/2057-1976/ab1674 · Cited by 32 · see citing works
Low power DDA-based instrumentation amplifier for neural recording applications in 65 nm CMOS
Avoli, M., Centurelli, F., Monsurrò, P., Scotti, G., & Trifiletti, A. (2018) · AEU - International Journal of Electronics and Communications · doi:10.1016/j.aeue.2018.05.014 · Cited by 30 · see citing works
Modeling of the Cell-Electrode Interface Noise for Microelectrode Arrays
Guo, J., Yuan, J. G., & Chan, M. (2012) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2012.2189569 · Cited by 30 · see citing works
A low-power low-noise CMOS bio-potential amplifier for multi-channel neural recording with active DC-rejection and current sharing
Jomehei, M. G., & Sheikhaei, S. (2018) · Microelectronics Journal · doi:10.1016/j.mejo.2018.11.021 · Cited by 30 · see citing works
Tunnel FET-based ultra-low power, low-noise amplifier design for bio-signal acquisition
Liu, H., Shoaran, M., Li, X., Datta, S., Schmid, A., & Narayanan, V. (2014) · International Symposium on Low Power Electronics and Design (ISLPED) · doi:10.1145/2627369.2627631 · Cited by 29 · see citing works
Self-citation
A 4 <formula formulatype="inline"><tex Notation="TeX">$\mu{\rm W}/{\rm Ch}$</tex></formula> Analog Front-End Module With Moderate Inversion and Power-Scalable Sampling Operation for 3-D Neural Microsystems
Al-Ashmouny, K. M., Chang, S.-I., & Yoon, E. (2012) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2012.2218105 · Cited by 28 · see citing works
Advances in Microelectronics for Implantable Medical Devices
Demosthenous, A. (2014) · Advances in Electronics · doi:10.1155/2014/981295 · Cited by 27 · see citing works
Analog Front-End Input-Impedance Boosting Techniques for Bio-Potential Monitoring—A Review
Yan, F., & Liu, J. (2024) · IEEE Transactions on Instrumentation and Measurement · doi:10.1109/tim.2024.3370766 · Cited by 24 · see citing works
A Low Noise Amplifier for Neural Spike Recording Interfaces
Ruiz-Amaya, J., Rodriguez-Perez, A., & Delgado-Restituto, M. (2015) · Sensors · doi:10.3390/s151025313 · Cited by 23 · see citing works
432 nW per Channel 130 nV/rtHz ECG Acquisition Front End With Multifrequency Chopping
Khatavkar, P., & Aniruddhan, S. (2019) · IEEE Transactions on Very Large Scale Integration (VLSI) Systems · doi:10.1109/tvlsi.2019.2910202 · Cited by 23 · see citing works
SOI FinFET based instrumentation amplifier for biomedical applications
Sonkusare, R., Joshi, O., & Rathod, S. S. (2019) · Microelectronics Journal · doi:10.1016/j.mejo.2019.07.005 · Cited by 23 · see citing works
A Low-Noise Biopotential CMOS Amplifier IC Using Low-Power Two-Stage OTA for Neural Recording Applications
Kim, H. S., & Cha, H. (2017) · Journal of Circuits Systems and Computers · doi:10.1142/s0218126618500688 · Cited by 23 · see citing works
A 1.8 $\mu$ W −65 dB THD ECG Acquisition Front-End IC Using a Bandpass Instrumentation Amplifier With Class-AB Output Configuration
Hsu, Y.-P., Liu, Z., & Hella, M. M. (2018) · IEEE Transactions on Circuits & Systems II Express Briefs · doi:10.1109/tcsii.2018.2809470 · Cited by 23 · see citing works
Noise Efficient Integrated Amplifier Designs for Biomedical Applications
Simmich, S., Bahr, A., & Rieger, R. (2021) · Electronics · doi:10.3390/electronics10131522 · Cited by 23 · see citing works
A fully-integrated 16-channel EEG readout front-end for neural recording applications
Nasserian, M., Peiravi, A., & Moradi, F. (2018) · AEU - International Journal of Electronics and Communications · doi:10.1016/j.aeue.2018.06.045 · Cited by 22 · see citing works
An ECG chopper amplifier achieving 0.92 NEF and 0.85 PEF with AC-coupled inverter-stacking for noise efficiency enhancement
Mondal, S., & Hall, D. A. (2017) · IEEE International Symposium on Circuits and Systems proceedings · doi:10.1109/iscas.2017.8050957 · Cited by 21 · see citing works
A Review of Microelectronic Systems and Circuit Techniques for Electrical Neural Recording Aimed at Closed-Loop Epilepsy Control
Ranjandish, R., & Schmid, A. (2020) · Sensors · doi:10.3390/s20195716 · Cited by 21 · see citing works
Self-citation
A CMOS Micro-power and Area Efficient Neural Recording and Stimulation Front-End for Biomedical Applications
Rehman, S. U., & Kamboh, A. M. (2014) · Circuits Systems and Signal Processing · doi:10.1007/s00034-014-9935-x · Cited by 19 · see citing works
Merging brain-computer interface and functional electrical stimulation technologies for movement restoration
Bouton, C. E. (2020) · Handbook of clinical neurology · doi:10.1016/b978-0-444-63934-9.00022-6 · Cited by 18 · see citing works
A 2.53 NEF 8-bit 10 kS/s 0.5 μm CMOS Neural Recording Read-Out Circuit with High Linearity for Neuromodulation Implants
Tasneem, N. T., & Mahbub, I. (2021) · Electronics · doi:10.3390/electronics10050590 · Cited by 17 · see citing works
A High CMRR Instrumentation Amplifier Employing Pseudo-Differential Inverter for Neural Signal Sensing
Zhou, Z., Zhu, L., Yang, R., Li, J., Wang, W., Pan, J., Liu, M., Wang, K., & Wang, Z. (2021) · IEEE Sensors Journal · doi:10.1109/jsen.2021.3130003 · Cited by 17 · see citing works
Design of a Low-Power Low-Noise ECG Amplifier for Smart Wearable Devices Using 180nm CMOS Technology
Laababid, Y., Khadiri, K. E., & Tahiri, A. (2022) · WSEAS TRANSACTIONS ON POWER SYSTEMS · doi:10.37394/232016.2022.17.18 · Cited by 15 · see citing works
A 20.3μW 1.9GΩ Input Impedance Capacitively-Coupled Chopper-Stabilized Amplifier for Bio-Potential Readout
Zhou, Y., Song, S., Zheng, Y., Yang, T., Li, M., Cao, Y., Zheng, F., Huang, K., Tan, Z., & Zhao, M. (2024) · IEEE Transactions on Circuits and Systems I Regular Papers · doi:10.1109/tcsi.2024.3351872 · Cited by 15 · see citing works
A 16-channel, 359 μW, parallel neural recording system using Walsh-Hadamard coding
Majidzadeh, V., Schmid, A., & Leblebici, Y. (2013) · Custom Integrated Circuits Conference · doi:10.1109/cicc.2013.6658512 · Cited by 14 · see citing works
Self-citation
Digitally assisted neural recording and spike detection multichannel integrated circuit designed in 180 nm CMOS technology
Kmon, P. (2014) · Microelectronics Journal · doi:10.1016/j.mejo.2014.04.031 · Cited by 13 · see citing works
Fast and effective method of CMRR enhancement for multichannel integrated circuits dedicated to biomedical measurements
Kmon, P., Gryboś, P., Żołądź, M., & Lisicka, A. (2015) · Electronics Letters · doi:10.1049/el.2015.1933 · Cited by 12 · see citing works
Survey on various architectures of preamplifiers for electroencephalogram (EEG) signal acquisition
Devi, S., Guha, K., Baishnab, K. L., Iannacci, J., & Narayan, K. S. (2022) · Microsystem Technologies · doi:10.1007/s00542-022-05253-4 · Cited by 12 · see citing works
Low Noise Amplifier in Smart Healthcare Applications
Bansal, M., & Jyoti (2019) · International Conference on Signal Processing and Integrated Networks (SPIN) · doi:10.1109/spin.2019.8711705 · Cited by 12 · see citing works
A compact, low input capacitance neural recording amplifier with Cin/Gain of 20fF.V/V
Ng, K. A., & Xu, Y. P. (2012) · IEEE Biomedical Circuits and Systems Conference (BioCAS) · doi:10.1109/biocas.2012.6418430 · Cited by 12 · see citing works
A 64-Channel Inverter-Based Neural Signal Recording Amplifier With a Novel Differential-Like OTA Achieving an NEF of 0.84
Xu, Q., Li, G., Liu, Y., Luo, F. C., & Xiao, Z. (2024) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2024.3363130 · Cited by 11 · see citing works
A low-power, low-noise, high-accurate epileptic-seizure detection system for wearable applications
Tohidi, M. M., Madsen, J. K., & Moradi, F. (2019) · Microelectronics Journal · doi:10.1016/j.mejo.2019.104600 · Cited by 11 · see citing works
A Low-Power High-Input-Impedance ECG Readout System Employing a Very High-Gain Amplification and a Signal-Folding Technique for Dry-Electrode Recording
Buaban, C., Ratametha, C., Limpisawas, T., Songthawornpong, T., Pholpoke, B., & Wattanapanitch, W. (2021) · IEEE Sensors Journal · doi:10.1109/jsen.2021.3087723 · Cited by 11 · see citing works
Design techniques and analysis of high-resolution neural recording systems targeting epilepsy focus localization
Shoaran, M., Pollo, C., Leblebici, Y., & Schmid, A. (2012) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2012.6347153 · Cited by 11 · see citing works
Self-citation
A low-power, low-area modular architecture for high density neural probes
Angotzi, G. N., & Berdondini, L. (2015) · International IEEE/EMBS Conference on Neural Engineering · doi:10.1109/ner.2015.7146674 · Cited by 10 · see citing works
Design and Analysis of Low Power Bio-amplifier with Current Mirror Topology at CMOS 45nm Technology Node
Kumar, A., Tripathi, S. L., Verma, C., Raboacă, M. S., Enescu, F. M., & Mihălţan, T. C. (2022) · International Conference on Electronics, Computers and Artificial Intelligence (ECAI) · doi:10.1109/ecai54874.2022.9847492 · Cited by 10 · see citing works
2.5D Heterogeneously Integrated Microsystem for High-Density Neural Sensing Applications
Huang, P.-T., Wu, S.-L., Huang, Y., Chou, L.-C., Huang, T.-C., Wang, T.-H., Lin, Y.-R., Cheng, C.-A., Shen, W.-W., Chuang, C.-T. K., et al. (2014) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2014.2385061 · Cited by 10 · see citing works
A low-power current-reuse analog front-end for multi-channel neural signal recording
Sepehrian, H., Mirbozorgi, S. A., & Gosselin, B. J. (2014) · IEEE International New Circuits and Systems Conference (NEWCAS) · doi:10.1109/newcas.2014.6934077 · Cited by 9 · see citing works
Energy-efficient low-noise 16-channel analog-front-end circuit for bio-potential acquisition
Wu, S.-L., Huang, P.-T., Huang, T.-C., Chen, K., Chiou, J., Chen, K.-H., Chiu, C.-T., Tong, H., Chuang, C.-T. K., & Hwang, W. (2014) · International Symposium on VLSI Design, Automation and Test · doi:10.1109/vlsi-dat.2014.6834893 · Cited by 9 · see citing works
A Power Efficient Low-noise and High Swing CMOS Amplifier for Neural Recording Applications
Naderi, K., Shad, E. H. T., Molinas, M., & Heidari, A. (2020) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc44109.2020.9175842 · Cited by 9 · see citing works
A Fully Differential Analog Front-End for Signal Processing from EMG Sensor in 28 nm FDSOI Technology
Kledrowetz, V., Prokop, R., Fujčík, L., & Háze, J. (2023) · Sensors · doi:10.3390/s23073422 · Cited by 8 · see citing works
Compact and Low Power Analog Front End with in-situ Data Decimator for High-Channel-Count ECoG Recording
Ashoori, E., Dávila-Montero, S., & Mason, A. J. (2018) · IEEE International Symposium on Circuits and Systems proceedings · doi:10.1109/iscas.2018.8351245 · Cited by 8 · see citing works
Light Modulation of Brain and Development of Relevant Equipment
Li, X., Liu, C., & Wang, R. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-191240 · Cited by 8 · see citing works
A multi-parameter bio-electric ASIC sensor with integrated 2-wire data transmission protocol for wearable healthcare system
Yang, G., Chen, J., Jönsson, F., Tenhunen, H., & Zheng, L. (2012) · Design, Automation, and Test in Europe · doi:10.1109/date.2012.6176512 · Cited by 8 · see citing works
Implantable Medical Devices for Wireless Optical Neuromodulation and Neural Recording: Energy-Efficient Integrated Circuit and System Design
Jia, Y., & Zhao, L. (2023) · IEEE Solid-State Circuits Magazine · doi:10.1109/mssc.2023.3305589 · Cited by 7 · see citing works
A 4-channel neural amplifier employing partial OTA sharing structure with variable gain and bandwidth for implantable neural recording applications
Ashayeri, M., & Yavari, M. (2024) · Alexandria Engineering Journal · doi:10.1016/j.aej.2024.08.090 · Cited by 7 · see citing works
Development of an ultra low noise, miniature signal conditioning device for vestibular evoked response recordings
Kumaragamage, C., Lithgow, B., & Moussavi, Z. (2014) · BioMedical Engineering OnLine · doi:10.1186/1475-925x-13-6 · Cited by 7 · see citing works
A multi-parameter bio-electric ASIC sensor with integrated 2-wire data transmission protocol for wearable healthcare system
Yang, G., Chen, J., Jönsson, F., Tenhunen, H., & Zheng, L. (2012) · Design, Automation, and Test in Europe · doi:10.5555/2492708.2492821 · Cited by 7 · see citing works
Design and Implementation of Low Noise Amplifier in Neural Signal Analysis
Bansal, M., & Singh, D. (2019) · Communications in computer and information science · doi:10.1007/978-981-15-1384-8_2 · Cited by 7 · see citing works
Modelling and analysis of a modified preamplifier for seizure detection
Devi, S., Guha, K., Laskar, N. M., Nath, S., Baishnab, K. L., Iannacci, J., & Narayan, K. S. (2021) · Microsystem Technologies · doi:10.1007/s00542-020-05114-y · Cited by 7 · see citing works
A multi-channel analog IC forin vitroneural recording
Feng, Y., Wang, Z., & Lü, X. (2016) · Journal of Semiconductors · doi:10.1088/1674-4926/37/2/025007 · Cited by 7 · see citing works
An Experimental Reliability Study of Pseudo-Resistors in Biomedical Applications
Reich, S., Fritschi, D., Sporer, M., & Ortmanns, M. (2022) · IEEE International Symposium on Circuits and Systems proceedings · doi:10.1109/iscas48785.2022.9937987 · Cited by 7 · see citing works
Low power amplifier for biopotential signal acquisition system
Pratyusha, K., Kumar, S., & Kumari, A. (2015) · International Conference on Advances in Computing, Communications and Informatics (ICACCI) · doi:10.1109/icacci.2015.7275629 · Cited by 7 · see citing works
A 1.8 µW area-efficient bio-potential amplifier with 90 dB DC offset suppression
Zhang, J., Chan, S. C., & Wang, L. (2014) · IEEE International Midwest Symposium on Circuits and Systems (MWSCAS) · doi:10.1109/mwscas.2014.6908408 · Cited by 6 · see citing works
A low-power capacitive-feedback CMOS neural recording amplifier for biomedical applications
Kim, H. S., & Cha, H. (2016) · International SoC Design Conference · doi:10.1109/isocc.2016.7799786 · Cited by 6 · see citing works
Telemetry-controlled simultaneous stimulation-and-recording device (SRD) to study interhemispheric cortical circuits in rat primary somatosensory (SI) cortex
Ramshur, J. T., Morshed, B. I., Curry, A. L. D. J., & Waters, R. S. (2019) · BMC Biomedical Engineering · doi:10.1186/s42490-019-0019-7 · Cited by 6 · see citing works
A 1V low-power low-noise biopotential amplifier based on flipped voltage follower
Farouk, T., Elkhatib, M., & Dessouky, M. A. (2015) · IEEE International Conference on Electronics, Circuits and Systems (ICECS) · doi:10.1109/icecs.2015.7440373 · Cited by 6 · see citing works
Ultra-Low Power Application-Specific Integrated Circuits for Sensing
Kassanos, P., Ip, H., & Yang, G. (2018) · Springer eBooks · doi:10.1007/978-3-319-69748-2_5 · Cited by 6 · see citing works
Facile Deep Brain Electrode Coating with MXene for Improved Electrode Performance
Kondrataviciute, L., Valiante, T. A., Milosevic, L., Kalia, L. V., Kim, D. W., & Kalia, S. K. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202501169 · Cited by 5 · see citing works
A CMOS frontend chip for implantable neural recording with wide voltage supply range
Liu, J., Zhang, X., Hu, X., Guo, Y., Li, P., Liu, M., Li, B., & Chen, H. (2015) · Journal of Semiconductors · doi:10.1088/1674-4926/36/10/105003 · Cited by 5 · see citing works
A novel compressive sensing architecture for high-density biological signal recording
Shoaran, M., Afshari, H., & Schmid, A. (2014) · IEEE Biomedical Circuits and Systems Conference (BioCAS) · doi:10.1109/biocas.2014.6981633 · Cited by 5 · see citing works
Self-citation
In Vitro Study of Artifact-Recovery Using a 32-Channel Neuromodulator Platform
Reich, S., Fritschi, D., Sporer, M., & Ortmanns, M. (2023) · IEEE Transactions on Circuits and Systems I Regular Papers · doi:10.1109/tcsi.2023.3255549 · Cited by 5 · see citing works
Design of low noise amplifier for sensor applications
Jana, D., & Mal, A. K. (2017) · Devices for Integrated Circuit (DevIC) · doi:10.1109/devic.2017.8073990 · Cited by 5 · see citing works
Compact, Programmable, Two-Stage Configuration for Implantable Biopotential Recording Amplifiers
Maghami, M. H., & Sodagar, A. M. (2019) · Journal of Circuits Systems and Computers · doi:10.1142/s0218126619200093 · Cited by 5 · see citing works
A 2 × 2 Neural Amplifier Macro-Pixel with Shared DC Servo Loop for High-Density Brain-Computer Interfaces
Abdelgaliel, B. H., Exalto, M., Ou-Yang, Y.-H., & Muratore, D. G. (2024) · IEEE Biomedical Circuits and Systems Conference (BioCAS) · doi:10.1109/biocas61083.2024.10798201 · Cited by 4 · see citing works
A low-noise fully differential recycling folded cascode neural amplifier
Cerida, S., Raygada, E., Silva, C., & Monge, M. (2015) · IEEE Latin American Symposium on Circuits and Systems (LASCAS) · doi:10.1109/lascas.2015.7250497 · Cited by 4 · see citing works
A low-power current-reuse dual-band analog front-end for multi-channel neural signal recording
Sepehrian, H., & Gosselin, B. J. (2014) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2014.6944818 · Cited by 4 · see citing works
Low-Gain, Low-Noise Integrated Neuronal Amplifier for Implantable Artifact-Reduction Recording System
Zbrzeski, A., Lewis, N., Rummens, F., Jung, R., N’Kaoua, G., Benazzouz, A., & Renaud, S. (2013) · Journal of Low Power Electronics and Applications · doi:10.3390/jlpea3030279 · Cited by 4 · see citing works
A low-noise gain-tunable amplifier for large array biopotential recording systems
Li, Y.-G., Haider, M. R., & Massoud, Y. (2012) · Analog Integrated Circuits and Signal Processing · doi:10.1007/s10470-012-0013-7 · Cited by 4 · see citing works
Continuous-time micropower interface for neural recording applications
Elia, M., Leene, L. B., & Constandinou, T. G. (2016) · IEEE International Symposium on Circuits and Systems proceedings · doi:10.1109/iscas.2016.7527295 · Cited by 3 · see citing works
Demonstration of a fully differential VGA chip with small THD for ECG acquisition system
Xiao, G., Qin, Y., Xu, W., Wei, B., Duan, J., & Wei, X. (2015) · Journal of Semiconductors · doi:10.1088/1674-4926/36/10/105005 · Cited by 3 · see citing works

A micropower neural recording amplifier with improved noise efficiency factor
Majidzadeh, V., Schmid, A., & Leblebici, Y. (2009) · European Conference on Circuit Theory and Design · doi:10.1109/ecctd.2009.5274982 · Cited by 18 · see citing works
Self-citation
Circuit Design for Ultra Low-Noise and Low-Power Sensor Interface
Majidzadeh, V., & Schmid, A. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6702-1_4
Self-citation
800 nW 43 nV/√Hz neural recording amplifier with enhanced noise efficiency factor
Liu, L., Zou, X., Goh, W. L., Ramamoorthy, R., Dawe, G. S., & Je, M. (2012) · Electronics Letters · doi:10.1049/el.2012.0685 · Cited by 51 · see citing works
Energy Efficient Low-Noise Multichannel Neural Amplifier in Submicron CMOS Process
Kmon, P., & Gryboś, P. (2013) · IEEE Transactions on Circuits and Systems I Regular Papers · doi:10.1109/tcsi.2012.2230504 · Cited by 61 · see citing works
An Energy-Efficient Micropower Neural Recording Amplifier
Wattanapanitch, W., Fee, M., & Sarpeshkar, R. (2007) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2007.907868 · Cited by 441 · see citing works

Authors: Majidzadeh, V., Schmid, A., & Leblebici, Y.
Affiliations: École Polytechnique Fédérale de Lausanne (CH)
ORCID: Schmid, Alexandre
Venue: IEEE Transactions on Biomedical Circuits and Systems
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Published: 2011-06
Volume: 5
Issue: 3
Pages: 262-271
ISSN: 1932-4545 (ISSN-L)
1940-9990
DOI: 10.1109/tbcas.2010.2078815
OpenAlex: W2164282321
Cited by: 165
References: 16
Citations by year: 2026: 1 · 2025: 3 · 2024: 7 · 2023: 4 · 2022: 9 · 2021: 8 · 2020: 8 · 2019: 15 · 2018: 13 · 2017: 13 · 2016: 15 · 2015: 21 · 2014: 19 · 2013: 13 · 2012: 12
FWCI: 9.09
Type: journal article
Language: en
Open access: green
infoscience.epfl.ch
Licence: ieeexplore.ieee.org/Xplorehelp/downloads/license-information/IEEE.html (vor)
Locations: IEEE Transactions on Biomedical Circuits and Systems (publishedVersion)
PubMed (publishedVersion)
Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion)
Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
Topics: Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Physical Sciences › Engineering › Electrical and Electronic Engineering › Radio Frequency Integrated Circuit Design
Keywords: noise efficiency factor, low-power amplifier, microelectrode arrays, cortical implants, crosstalk, common-mode rejection ratio, amplifier nonlinearity, input-referred noise, energy efficiency

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Energy Efficient Low-Noise Neural Recording Amplifier With Enhanced Noise Efficiency Factor

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks