International Diabetes Federation: a consensus on Type 2 diabetes prevention
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Aims Early intervention and avoidance or delay of progression to Type 2 diabetes is of enormous benefit to patients in terms of increasing life expectancy and quality of life, and potentially in economic terms for society and health‐care payers. To address the growing impact of Type 2 diabetes the International Diabetes Federation (IDF) Taskforce on Prevention and Epidemiology convened a consensus workshop in 2006. The primary goal of the workshop and this document was the prevention of Type 2 diabetes in both the developed and developing world. A second aim was to reduce the risk of cardiovascular disease in people who are identified as being at a higher risk of Type 2 diabetes. The IDF plan for prevention of Type 2 diabetes is based on controlling modifiable risk factors and can be divided into two target groups: People at high risk of developing Type 2 diabetes The entire population. Conclusions In planning national measures for the prevention of Type 2 diabetes, both groups should be targeted simultaneously with lifestyle modification the primary goal through a stepwise approach. In addition, it is important that all activities are tailored to the specific local situation. Further information on the prevention of diabetes can be found on the IDF website: http://www.idf.org/prevention .
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Early intervention is critical to improve the progression of complications and reduce the long-term cost of diabetes.
“Early intervention has been shown to be critical to improve the progression of the complications and reduce the cost of the disease in the long term [7].”
From A Novel Testing Model for Opportunistic Screening of Pre-Diabetes and Diabetes among U.S. Adults (2015) · cites this paper as [7]
The IDF strategy for diabetes prevention section says early detection and intervention can reduce the incidence of diabetes and its complications. The Health economics section describes economic benefits as potential and says long-term cost savings from avoided complications are not yet established by follow-up data. The claim overstates the evidence by presenting a reduction in long-term costs as demonstrated. (LLM, conf=0.88)
Experimental — accuracy not yet measuredPCOS is identified by the International Diabetes Federation as an independent risk factor for type 2 diabetes.
“PCOShasbeenidentified by the International Diabetes Federation as an independent risk factor for DM2 (Alberti et al. , 2007); hence the role of metformin and lifestyle in preventing DM2 in PCOS is highly relevant.”
From Metformin and lifestyle modification in polycystic ovary syndrome: systematic review and meta-analysis (2015) · cites this paper as Alberti et al. , 2007
The Causes of diabetes and Other risk factors sections discuss type 2 diabetes risk factors, but the available passages do not mention PCOS or identify it as an independent risk factor. Searches for “PCOS,” “polycystic,” and “polycystic ovarian syndrome” found no such statement; the indexed copy of Table 1 contains only its heading and a partial header. (LLM, conf=0.70)
Experimental — accuracy not yet measuredPCOS is listed by the International Diabetes Federation as a non-modifiable risk factor for DM2.
“In this context, PCOS is listed by the International Diabetes Federation as a non-modifiable risk factor for DM2. 106”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [106]
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“indicating that simple, practical, non-invasive, and inexpensive methods are needed to identify individuals at high risk for IGT and diabetes and to limit the proportion of the population requiring diagnostic glucose tolerance tests [25].”
MethodHu, R., Li, Y., Lv, Q., Wu, T., & Tong, N. (2015) · Clinical Therapeutics · doi:10.1016/j.clinthera.2015.05.504 · Cited by 32 · see citing works
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Crandall, J. P., Dabelea, D., Knowler, W. C., Nathan, D. M., Temprosa, M., DPP Research Group, Bray, G. A., Gadde, K. M., Culbert, I. W., Arceneaux, J., et al. (2025) · Diabetes Care · doi:10.2337/dc25-0014 · Cited by 29 · see citing works
Khamseh, M. E., Ansari, M., Malek, M., Shafiee, G., & Baradaran, H. (2011) · Journal of Diabetes Science and Technology · doi:10.1177/193229681100500228 · Cited by 20 · see citing works
Wang, Y., Feng, Q., Niu, X., Xu, K., Wang, Y., Wang, J., Li, Q., Mao, Y., & Gao, S. (2016) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2016/9417362 · Cited by 16 · see citing works
Digital Health Interventions to Prevent Type 2 Diabetes Mellitus: Systematic Review
Duong, T., Olsen, Q., Menon, A., Woods, L., Wang, W., Varnfield, M., Jiang, L., & Sullivan, C. (2025) · Journal of Medical Internet Research · doi:10.2196/67507 · Cited by 14 · see citing works
Muilwijk, M., Stronks, K., Qureshi, S. A., Beune, E., Celis-Morales, C., Gill, J., Sheikh, A., Jenum, A. K., & van Valkengoed, I. G. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-012783 · Cited by 5 · see citing works
- Authors
- Alberti, K. G. M. M., Zimmet, P., & Shaw, J.
- Affiliations
- St Mary's Hospital (GB)
- Corresponding author
- Alberti, K. G. M. M.
- ORCID
- Venue
- Diabetic Medicine
- Publisher
- Wiley
- Published
- 2007-04-26
- Volume
- 24
- Issue
- 5
- Pages
- 451-463
- ISSN
- 0742-3071 (ISSN-L)
- 1464-5491
- OpenAlex
- W2159806894
- Cited by
- 778
- References
- 56
- Citations by year
- 2026: 8 · 2025: 9 · 2024: 31 · 2023: 30 · 2022: 34 · 2021: 33 · 2020: 33 · 2019: 42 · 2018: 44 · 2017: 55 · 2016: 53 · 2015: 56 · 2014: 51 · 2013: 60 · 2012: 67
- FWCI
- 29.47
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Diabetic Medicine (publishedVersion)
- PubMed (publishedVersion)
- eCite Digital Repository (University of Tasmania) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- type 2 diabetes prevention, International Diabetes Federation, consensus recommendations, vulnerable populations, lifestyle modification, cardiovascular risk reduction, modifiable risk factors, diabetes epidemiology
- MeSH terms
- Adult, Cost-Benefit Analysis, Diabetes Mellitus, Type 2, Female, Health Education, Health Promotion, Humans, International Cooperation, Male, Middle Aged, Risk Factors, Societies, Medical
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