ggplot2: Elegant Graphics for Data Analysis

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Blanco-Melo, D., Nilsson-Payant, B. E., Liu, W.-C., Uhl, S., Hoagland, D., Møller, R., Jordan, T. X., Oishi, K., Panis, M., Sachs, D., et al. (2020) · Cell · doi:10.1016/j.cell.2020.04.026 · Cited by 4,222

Definitions, methods, and applications in interpretable machine learning

Murdoch, W. J., Singh, C., Kumbier, K., Abbasi-Asl, R., & Yu, B. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1900654116 · Cited by 2,167

Google Scholar, Web of Science, and Scopus: A systematic comparison of citations in 252 subject categories

Martín-Martín, A., Orduna-Malea, E., Thelwall, M., & Delgado López-Cózar, E. (2018) · Journal of Informetrics · doi:10.1016/j.joi.2018.09.002 · Cited by 1,990

Biochar and its effects on plant productivity and nutrient cycling: A meta-analysis

Biederman, L. A., & Harpole, W. S. (2013) · GCB Bioenergy · doi:10.1111/gcbb.12037 · Cited by 1,737

Gut-microbiota-targeted diets modulate human immune status

Wastyk, H. C., Fragiadakis, G. K., Perelman, D., Dahan, D., Merrill, B. D., Yu, F. B., Topf, M., Gonzalez, C. G., Van Treuren, W., Han, S., et al. (2021) · Cell · doi:10.1016/j.cell.2021.06.019 · Cited by 1,385

Clustering trees: a visualization for evaluating clusterings at multiple resolutions

Zappia, L., & Oshlack, A. (2018) · GigaScience · doi:10.1093/gigascience/giy083 · Cited by 1,064

gprofiler2 -- an R package for gene list functional enrichment analysis and namespace conversion toolset g:Profiler

Kolberg, L., Raudvere, U., Kuzmin, I., Vilo, J., & Peterson, H. (2020) · F1000Research · doi:10.12688/f1000research.24956.2 · Cited by 1,098

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Guilliams, M., Bonnardel, J., Haest, B., Vanderborght, B., Wagner, C., Remmerie, A., Bujko, A., Martens, L., Thoné, T., Browaeys, R., et al. (2022) · Cell · doi:10.1016/j.cell.2021.12.018 · Cited by 985

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

Richardson, T. G., Sanderson, E., Palmer, T. M., Ala-Korpela, M., Ference, B. A., Davey Smith, G., & Holmes, M. V. (2020) · PLOS Medicine · doi:10.1371/journal.pmed.1003062 · Cited by 843

Splatter: simulation of single-cell RNA sequencing data

Zappia, L., Phipson, B., & Oshlack, A. (2017) · Genome Biology · doi:10.1186/s13059-017-1305-0 · Cited by 905

A phase Ib trial of personalized neoantigen therapy plus anti-PD-1 in patients with advanced melanoma, non-small cell lung cancer, or bladder cancer

Ott, P. A., Hu-Lieskovan, S., Chmielowski, B., Govindan, R., Naing, A., Bhardwaj, N., Margolin, K., Awad, M. M., Hellmann, M. D., Lin, J. J., et al. (2020) · Cell · doi:10.1016/j.cell.2020.08.053 · Cited by 738

TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge

Nugent, A. A., Lin, K., van Lengerich, B., Lianoglou, S., Przybyla, L., Davis, S. S., Llapashtica, C., Wang, J., Kim, D. J., Xia, D., et al. (2020) · Neuron · doi:10.1016/j.neuron.2019.12.007 · Cited by 745

TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Molgora, M., Esaulova, E., Vermi, W., Hou, J., Chen, Y., Luo, J., Brioschi, S., Bugatti, M., Omodei, A. S., Ricci, B., et al. (2020) · Cell · doi:10.1016/j.cell.2020.07.013 · Cited by 656

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection

Hudson, W. H., Gensheimer, J., Hashimoto, M., Wieland, A., Valanparambil, R. M., Li, P., Lin, J.-X., Konieczny, B. T., Im, S. J., Freeman, G. J., et al. (2019) · Immunity · doi:10.1016/j.immuni.2019.11.002 · Cited by 656

Complete genomic and epigenetic maps of human centromeres

Altemose, N., Logsdon, G. A., Bzikadze, A. V., Sidhwani, P., Langley, S. A., Caldas, G. V., Hoyt, S. J., Uralsky, L., Ryabov, F. D., Shew, C. J., et al. (2022) · Science · doi:10.1126/science.abl4178 · Cited by 618

Twenty-first Century Trends in the Global Epidemiology of Pediatric-Onset Inflammatory Bowel Disease: Systematic Review

Kuenzig, M. E., Fung, S. G., Marderfeld, L., Mak, J. W. Y., Kaplan, G. G., Ng, S. C., Wilson, D. C., Cameron, F., Henderson, P., Kotze, P. G., et al. (2022) · Gastroenterology · doi:10.1053/j.gastro.2021.12.282 · Cited by 608

Comparison of the accuracy of human readers versus machine-learning algorithms for pigmented skin lesion classification: an open, web-based, international, diagnostic study

Tschandl, P., Codella, N., Akay, B. N., Argenziano, G., Braun, R. P., Cabo, H., Gutman, D., Halpern, A., Helba, B., Hofmann-Wellenhof, R., et al. (2019) · The Lancet Oncology · doi:10.1016/s1470-2045(19)30333-x · Cited by 555

Widespread and Functional RNA Circularization in Localized Prostate Cancer

Chen, S., Huang, V., Xu, X., Livingstone, J., Soares, F., Jeon, J., Zeng, Y., Hua, J. T., Petricca, J., Guo, H., et al. (2019) · Cell · doi:10.1016/j.cell.2019.01.025 · Cited by 544

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Wendisch, D., Dietrich, O., Mari, T., von Stillfried, S., Ibarra, I. L., Mittermaier, M., Mache, C., Chua, R. L., Knoll, R., Timm, S., et al. (2021) · Cell · doi:10.1016/j.cell.2021.11.033 · Cited by 528

Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial

Behr, J., Prasse, A., Kreuter, M., Johow, J., Rabe, K. F., Bonella, F., Bonnet, R., Grohe, C., Held, M., Wilkens, H., et al. (2021) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30554-3 · Cited by 522

A Quantitative Proteome Map of the Human Body

Jiang, L., Wang, M., Lin, S., Jian, R., Li, X., Chan, J., Dong, G., Fang, H., Robinson, A. E., Aguet, F., et al. (2020) · Cell · doi:10.1016/j.cell.2020.08.036 · Cited by 458

Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy

Luoma, A. M., Suo, S., Williams, H. L., Sharova, T., Sullivan, K., Manos, M., Bowling, P., Hodi, F. S., Rahma, O., Sullivan, R. J., et al. (2020) · Cell · doi:10.1016/j.cell.2020.06.001 · Cited by 484

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

McDonald, M. M., Khoo, W. H., Ng, P. Y., Xiao, Y., Zamerli, J., Thatcher, P., Kyaw, W., Pathmanandavel, K., Grootveld, A. K., Moran, I., et al. (2021) · Cell · doi:10.1016/j.cell.2021.02.002 · Cited by 433

Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging

Ma, S., Sun, S., Geng, L., Song, M., Wang, W., Ye, Y., Ji, Q., Zou, Z., Wang, S., He, X., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.008 · Cited by 349

Microplastic contamination of drinking water: A systematic review

Danopoulos, E., Twiddy, M., & Rotchell, J. M. (2020) · PLOS ONE · doi:10.1371/journal.pone.0236838 · Cited by 341

Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study.

Richardson, T. G., Sanderson, E., Elsworth, B., Tilling, K., & Davey Smith, G. (2019) · doi:10.1101/19008011 · Cited by 321

Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing

Willenborg, S., Sanin, D. E., Jais, A., Ding, X., Ulas, T., Nüchel, J., Popović, M., MacVicar, T., Langer, T., Schultze, J. L., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.10.004 · Cited by 310

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

Richardson, T. G., Leyden, G. M., Wang, Q., Bell, J. A., Elsworth, B., Davey Smith, G., & Holmes, M. V. (2022) · PLOS Biology · doi:10.1371/journal.pbio.3001547 · Cited by 304

Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq

Swanson, E., Lord, C., Reading, J., Heubeck, A. T., Genge, P. C., Thomson, Z., Weiss, M. D., Li, X.-J., Savage, A. K., Green, R. R., et al. (2021) · eLife · doi:10.7554/elife.63632 · Cited by 267

Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats.

Knight, P., Chellian, R., Wilson, R., Behnood-Rod, A., Panunzio, S., & Bruijnzeel, A. W. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173168 · Cited by 252

Validation of a Machine Learning Model That Outperforms Clinical Risk Scoring Systems for Upper Gastrointestinal Bleeding

Shung, D. L., Au, B., Taylor, R. A., Tay, J. K., Laursen, S. B., Stanley, A. J., Dalton, H. R., Ngu, J., Schultz, M., & Laine, L. (2020) · Gastroenterology · doi:10.1053/j.gastro.2019.09.009 · Cited by 227

Functional inference of gene regulation using single-cell multi-omics

Kartha, V. K., Duarte, F. M., Hu, Y., Ma, S., Chew, J. G., Lareau, C. A., Earl, A., Burkett, Z. D., Kohlway, A. S., Lebofsky, R., et al. (2022) · Cell Genomics · doi:10.1016/j.xgen.2022.100166 · Cited by 224

Critical evaluation of biodegradation studies on synthetic plastics through a systematic literature review

Matjašič, T., Simčič, T., Medvešček, N., Bajt, O., Dreo, T., & Mori, N. (2021) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.141959 · Cited by 229

Metformin decelerates aging clock in male monkeys

Yang, Y., Lu, X., Liu, N., Ma, S., Zhang, H., Zhang, Z., Yang, K., Jiang, M., Zheng, Z., Qiao, Y., et al. (2024) · Cell · doi:10.1016/j.cell.2024.08.021 · Cited by 227

Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration

Achuthan, V., Perreira, J. M., Sowd, G. A., Puray-Chavez, M., McDougall, W. M., Paulucci-Holthauzen, A., Wu, X., Fadel, H. J., Poeschla, E. M., Multani, A. S., et al. (2018) · Cell Host & Microbe · doi:10.1016/j.chom.2018.08.002 · Cited by 205

Sounding out ecoacoustic metrics: Avian species richness is predicted by acoustic indices in temperate but not tropical habitats

Eldridge, A., Guyot, P., Moscoso, P., Johnston, A., Eyre-Walker, Y., & Peck, M. (2018) · Ecological Indicators · doi:10.1016/j.ecolind.2018.06.012 · Cited by 209

Single-cell atlas of healthy human blood unveils age-related loss of NKG2C+GZMB−CD8+ memory T cells and accumulation of type 2 memory T cells

Terekhova, M., Swain, A., Bohacova, P., Aladyeva, E., Arthur, L., Laha, A., Mogilenko, D. A., Burdess, S., Sukhov, V., Kleverov, D., et al. (2023) · Immunity · doi:10.1016/j.immuni.2023.10.013 · Cited by 199

Multibatch TMT reveals false positives, batch effects and missing values

Brenes, A., Hukelmann, J., Bensaddek, D., & Lamond, A. I. (2019) · Molecular & Cellular Proteomics · doi:10.1074/mcp.ra119.001472 · Cited by 196

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β

Komuczki, J., Tuzlak, S., Friebel, E., Hartwig, T., Spath, S., Rosenstiel, P., Waisman, A., Opitz, L., Oukka, M., Schreiner, B., et al. (2019) · Immunity · doi:10.1016/j.immuni.2019.04.006 · Cited by 201

Towards integrating personalized feedback research into clinical practice: Development of the Trier Treatment Navigator (TTN)

Lutz, W., Rubel, J. A., Schwartz, B., Schilling, V., & Deisenhofer, A.-K. (2019) · Behaviour Research and Therapy · doi:10.1016/j.brat.2019.103438 · Cited by 196

African lungfish genome sheds light on the vertebrate water-to-land transition

Wang, K., Wang, J., Zhu, C., Yang, L., Ren, Y., Ruan, J., Fan, G., Hu, J., Xu, W., Bi, X., et al. (2021) · Cell · doi:10.1016/j.cell.2021.01.047 · Cited by 192

Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues.

Ma, S., Wang, S., Ye, Y., Ren, J., Chen, R., Li, W., Li, J., Zhao, L., Zhao, Q., Sun, G., et al. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2022.04.017 · Cited by 189

Enhancer viruses for combinatorial cell-subclass-specific labeling

Graybuck, L. T., Daigle, T. L., Sedeño-Cortés, A. E., Walker, M., Kalmbach, B., Lenz, G. H., Morin, E., Nguyen, T. N., Garren, E., Bendrick, J. L., et al. (2021) · Neuron · doi:10.1016/j.neuron.2021.03.011 · Cited by 187

Heterogeneity in NECTIN4 Expression Across Molecular Subtypes of Urothelial Cancer Mediates Sensitivity to Enfortumab Vedotin

(2021) · doi:10.1158/1078-0432.ccr-20-4175 · Cited by 172

Chronic stress primes innate immune responses in mice and humans

Barrett, T. J., Corr, E. M., van Solingen, C., Schlamp, F., Brown, E. J., Koelwyn, G. J., Lee, A. H., Shanley, L. C., Spruill, T. M., Bozal, F., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109595 · Cited by 169

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain

Zhan, L., Krabbe, G., Du, F., Jones, I., Reichert, M. C., Telpoukhovskaia, M., Kodama, L., Wang, C., Cho, S.-H., Sayed, F., et al. (2019) · PLOS Biology · doi:10.1371/journal.pbio.3000134 · Cited by 163

Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity

Fenton, T. M., Jørgensen, P. B., Niss, K., Rubin, S. J. S., Mörbe, U. M., Riis, L. B., Da Silva, C., Plumb, A., Vandamme, J., Jakobsen, H. L., et al. (2020) · Immunity · doi:10.1016/j.immuni.2020.02.001 · Cited by 145

Non-Targeted Metabolomics and Associations with per- and Polyfluoroalkyl Substances (PFAS) Exposure in Humans: A Scoping Review

Guo, P., Furnary, T., Vasiliou, V., Yan, Q., Nyhan, K., Jones, D. P., Johnson, C. H., & Liew, Z. (2022) · Environment International · doi:10.1016/j.envint.2022.107159 · Cited by 145

Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain

Venturino, A., Schulz, R., De Jesús-Cortés, H., Maes, M. E., Nagy, B., Reilly-Andújar, F., Colombo, G., Cubero, R. J. A., Schoot Uiterkamp, F. E., Bear, M. F., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109313 · Cited by 140

did2s: Two-Stage Difference-in-Differences

Butts, K., & Gardner, J. (2022) · The R Journal · doi:10.32614/rj-2022-048 · Cited by 133

The proteomic landscape of synaptic diversity across brain regions and cell types

van Oostrum, M., Blok, T. M., Giandomenico, S. L., tom Dieck, S., Tushev, G., Fürst, N., Langer, J. D., & Schuman, E. M. (2023) · Cell · doi:10.1016/j.cell.2023.09.028 · Cited by 135

Mining microbes for mental health: determining the role of microbial metabolic pathways in human brain health and disease

Spichak, S., Bastiaanssen, T. F. S., Berding, K., Vlckova, K., Clarke, G., Dinan, T. G., & Cryan, J. F. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.044 · Cited by 127

A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver

Inverso, D., Shi, J., Lee, K. H., Jakab, M., Ben-Moshe, S., Kulkarni, S. R., Schneider, M., Wang, G., Komeili, M., Vélez, P. A., et al. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.05.001 · Cited by 114

Island songbirds as windows into evolution in small populations

Leroy, T., Rousselle, M., Tilak, M.-K., Caizergues, A. E., Scornavacca, C., Recuerda, M., Fuchs, J., Illera, J. C., De Swardt, D. H., Blanco, G., et al. (2021) · Current Biology · doi:10.1016/j.cub.2020.12.040 · Cited by 113

Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer

Rosendahl Huber, A., Pleguezuelos-Manzano, C., Puschhof, J., Ubels, J., Boot, C., Saftien, A., Verheul, M., Trabut, L. T., Groenen, N., van Roosmalen, M., et al. (2024) · Cancer Cell · doi:10.1016/j.ccell.2024.02.009 · Cited by 106

Process efficiency and ventilation requirement in black soldier fly larvae composting of substrates with high water content

Lalander, C., Ermolaev, E., Wiklicky, V., & Vinnerås, B. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138968 · Cited by 106

AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

Li, H., Liu, Z., Liu, L., Zhang, H., Han, C., Girard, L., Park, H., Zhang, A., Dong, C., Ye, J., et al. (2022) · Cell Reports Medicine · doi:10.1016/j.xcrm.2022.100554 · Cited by 102

Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome

Martinez-Ara, M., Comoglio, F., van Arensbergen, J., & van Steensel, B. (2022) · Molecular Cell · doi:10.1016/j.molcel.2022.04.009 · Cited by 101

Temporal dissection of an enhancer cluster reveals distinct temporal and functional contributions of individual elements

Thomas, H. F., Kotova, E., Jayaram, S., Pilz, A., Romeike, M., Lackner, A., Penz, T., Bock, C., Leeb, M., Halbritter, F., et al. (2021) · Molecular Cell · doi:10.1016/j.molcel.2020.12.047 · Cited by 98

Using learning analytics to understand student perceptions of peer feedback

Misiejuk, K., Wasson, B., & Egelandsdal, K. (2021) · Computers in Human Behavior · doi:10.1016/j.chb.2020.106658 · Cited by 98

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

De Ponti, F. F., Bujko, A., Liu, Z., Collins, P. J., Schuermans, S., Maueroder, C., Amstelveen, S., Thoné, T., Martens, L., McKendrick, J. G., et al. (2025) · Immunity · doi:10.1016/j.immuni.2025.01.002 · Cited by 94

Looking for the lighthouse: A systematic review of advanced theory-of-mind tests beyond preschool

Osterhaus, C., & Bosacki, S. L. (2022) · Developmental Review · doi:10.1016/j.dr.2022.101021 · Cited by 94

CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories

Villa, C. E., Cheroni, C., Dotter, C. P., López-Tóbon, A., Oliveira, B., Sacco, R., Yahya, A. Ç., Morandell, J., Gabriele, M., Tavakoli, M. R., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110615 · Cited by 92

Breaking new ground on human health and well-being with epigenetic clocks: A systematic review and meta-analysis of epigenetic age acceleration associations

Chervova, O., Panteleeva, K., Chernysheva, E., Widayati, T. A., Baronik, Ž. F., Hrbková, N., Schneider, J. L., Bobak, M., Beck, S., & Voloshin, V. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102552 · Cited by 91

Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation

Lee, S. C., Adams, D. W., Ipsaro, J. J., Cahn, J., Lynn, J., Kim, H.-S., Berube, B., Major, V., Calarco, J. P., LeBlanc, C., et al. (2023) · Cell · doi:10.1016/j.cell.2023.08.001 · Cited by 89

Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth

McKee, A. M., Kirkup, B. M., Madgwick, M., Fowler, W. J., Price, C. A., Dreger, S. A., Ansorge, R., Makin, K. A., Caim, S., Le Gall, G., et al. (2021) · iScience · doi:10.1016/j.isci.2021.103012 · Cited by 81

Deciphering the decline of metabolic elasticity in aging and obesity

Zhou, Q., Yu, L., Cook, J. R., Qiang, L., & Sun, L. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.08.001 · Cited by 80

Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system

Ramirez, P., Zuniga, G., Sun, W., Beckmann, A., Ochoa, E., DeVos, S. L., Hyman, B., Chiu, G., Roy, E. R., Cao, W., et al. (2022) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2021.102181 · Cited by 79

Biochar amendment stimulates utilization of plant-derived carbon by soil bacteria in an intercropping system

Liao, H., Li, Y., & Yao, H. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01361 · Cited by 76

Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice

Berghoff, S. A., Spieth, L., Sun, T., Hosang, L., Depp, C., Sasmita, A. O., Vasileva, M. H., Scholz, P., Zhao, Y., Krueger-Burg, D., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109889 · Cited by 76

Conspiratorial thinking during COVID-19: The roles of paranoia, delusion-proneness, and intolerance of uncertainty

Larsen, E. M., Donaldson, K. R., Liew, M., & Mohanty, A. (2020) · doi:10.31234/osf.io/mb65f · Cited by 71

WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity

Elbæk, C. R., Petrosius, V., Benada, J., Erichsen, L., Damgaard, R. B., & Sørensen, C. S. (2022) · Cell Reports · doi:10.1016/j.celrep.2021.110261 · Cited by 64

Variability in Autism Symptom Trajectories Using Repeated Observations From 14 to 36 Months of Age

Kim, S. H., Bal, V. H., Benrey, N., Choi, Y. B., Guthrie, W., Colombi, C., & Lord, C. (2018) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2018.05.026 · Cited by 70

A sex-specific switch between visual and olfactory inputs underlies adaptive sex differences in behavior

Nojima, T., Rings, A., Allen, A. M., Otto, N., Verschut, T. A., Billeter, J.-C., Neville, M. C., & Goodwin, S. F. (2021) · Current Biology · doi:10.1016/j.cub.2020.12.047 · Cited by 69

Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes

Milenkovic, D., Misic, J., Hevler, J. F., Molinié, T., Chung, I., Atanassov, I., Li, X., Filograna, R., Mesaros, A., Mourier, A., et al. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.07.015 · Cited by 68

Microplastics in a deep, dimictic lake of the North German Plain with special regard to vertical distribution patterns

Tamminga, M., & Fischer, E. K. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.115507 · Cited by 68

First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Zwirner, S., Abu Rmilah, A. A., Klotz, S., Pfaffenroth, B., Kloevekorn, P., Moschopoulou, A. A., Schuette, S., Haag, M., Selig, R., Li, K., et al. (2024) · Cell · doi:10.1016/j.cell.2024.02.023 · Cited by 65

Structural elements promote architectural stripe formation and facilitate ultra-long-range gene regulation at a human disease locus

Chen, L.-F., Long, H. K., Park, M., Swigut, T., Boettiger, A. N., & Wysocka, J. (2023) · Molecular Cell · doi:10.1016/j.molcel.2023.03.009 · Cited by 66

The gut microbiota promotes pain in fibromyalgia

Cai, W., Haddad, M., Haddad, R., Kesten, I., Hoffman, T., Laan, R., Westfall, S., Defaye, M., Abdullah, N. S., Wong, C., et al. (2025) · Neuron · doi:10.1016/j.neuron.2025.03.032 · Cited by 59

Development of the gut microbiota in healthy children in the first ten years of life: associations with internalizing and externalizing behavior

Ou, Y., Belzer, C., Smidt, H., & de Weerth, C. (2022) · Gut Microbes · doi:10.1080/19490976.2022.2038853 · Cited by 54

IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy

Pan, L., Cho, K.-S., Wei, X., Xu, F., Lennikov, A., Hu, G., Tang, J., Guo, S., Chen, J., Kriukov, E., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112889 · Cited by 52

Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen

O’Meara, T. R., O’Meara, M. J., Polvi, E. J., Pourhaghighi, M. R., Liston, S. D., Lin, Z.-Y., Veri, A. O., Emili, A., Gingras, A.-C., & Cowen, L. E. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000358 · Cited by 49

PDAC-ANN: an artificial neural network to predict pancreatic ductal adenocarcinoma based on gene expression

Almeida, P. P., Cardoso, C. P., & de Freitas, L. M. (2020) · BMC Cancer · doi:10.1186/s12885-020-6533-0 · Cited by 48

This Item Might Reinforce Your Opinion: Obfuscation and Labeling of Search Results to Mitigate Confirmation Bias

Rieger, A., Draws, T., Theune, M., & Tintarev, N. (2021) · Proceedings of the 32st ACM Conference on Hypertext and Social Media · doi:10.1145/3465336.3475101 · Cited by 48

Microplastic ingestion and plastic additive detection in pelagic squid and fish: Implications for bioindicators and plastic tracers in open oceanic food webs

Sambolino, A., Iniguez, E., Herrera, I., Kaufmann, M., Dinis, A., & Cordeiro, N. (2023) · Science of The Total Environment · doi:10.1016/j.scitotenv.2023.164952 · Cited by 47

Post-exercise hypotension and skeletal muscle oxygenation is regulated by nitrate-reducing activity of oral bacteria

Clarke, C., Kiernan, M., Willis, J. R., Gallardo-Alfaro, L., Casas-Agustench, P., White, D., Hickson, M., Gabaldon, T., & Bescos, R. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.07.035 · Cited by 49

Seasonal dynamics of bacterial communities in the surface seawater around subtropical Xiamen Island, China, as determined by 16S rRNA gene profiling

Wang, Y., Liu, Y., Wang, J., Luo, T., Zhang, R., Sun, J., Zheng, Q., & Jiao, N. (2019) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2019.03.035 · Cited by 45

Identification of Iron-Sulfur (Fe-S) Cluster and Zinc (Zn) Binding Sites Within Proteomes Predicted by DeepMind’s AlphaFold2 Program Dramatically Expands the Metalloproteome

Wehrspan, Z. J., McDonnell, R. T., & Elcock, A. H. (2022) · Journal of Molecular Biology · doi:10.1016/j.jmb.2021.167377 · Cited by 45

AlzBase: An Integrative Database for Gene Dysregulation in Alzheimer’s Disease

Bai, Z., Han, G., Xie, B., Wang, J., Song, F., Peng, X., & Lei, H. (2016) · Molecular Neurobiology · doi:10.1007/s12035-014-9011-3 · Cited by 44

A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway

Yoon, S.-B., Hong, H., Lim, H.-J., Choi, J. H., Choi, Y. P., Seo, S. W., Lee, H. W., Chae, C. H., Park, W.-K., Kim, H. Y., et al. (2023) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.12.001 · Cited by 44

Methionine transsulfuration pathway is upregulated in long-lived humans

Mota-Martorell, N., Jové, M., Borrás, C., Berdún, R., Obis, È., Sol, J., Cabré, R., Pradas, I., Galo-Licona, J. D., Puig, J., et al. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.11.026 · Cited by 43

The gut microbiota profile in psoriasis: a Brazilian case-control study

Schade, L., Mesa, D., Faria, A. R., Santamaria, J. R., Xavier, C. A., Ribeiro, D., Hajar, F. N., & Azevedo, V. F. (2022) · Letters in Applied Microbiology · doi:10.1111/lam.13630 · Cited by 42

Retention of participants recruited to a multi-year longitudinal study via Prolific

Kothe, E. J., & Ling, M. (2019) · doi:10.31234/osf.io/5yv2u · Cited by 42

Fully Automated 3-D Ultrasound Segmentation of the Placenta, Amniotic Fluid, and Fetus for Early Pregnancy Assessment

Looney, P., Yin, Y., Collins, S. L., Nicolaides, K. H., Plasencia, W., Molloholli, M., Natsis, S., & Stevenson, G. N. (2021) · IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control · doi:10.1109/tuffc.2021.3052143 · Cited by 40

The effects of testosterone on the physiological response to social and somatic stressors

Kutlikova, H. H., Durdiaková, J. B., Wagner, B., Vlček, M., Eisenegger, C., Lamm, C., & Riečanský, I. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104693 · Cited by 40

Long-range regulation of transcription scales with genomic distance in a gene-specific manner

Jensen, C. L., Chen, L.-F., Swigut, T., Crocker, O. J., Yao, D., Bassik, M. C., Ferrell, J. E., Boettiger, A. N., & Wysocka, J. (2025) · Molecular Cell · doi:10.1016/j.molcel.2024.10.021 · Cited by 39

Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency

Root, J., Mendsaikhan, A., Taylor, G., Merino, P., Nandy, S., Wang, M., Araujo, L. T., Ryu, D., Holler, C., Thompson, B. M., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114985 · Cited by 39

BHA-CS: A novel cognitive composite for Alzheimer's disease and related disorders

Tsoy, E., Erlhoff, S. J., Goode, C. A., Dorsman, K. A., Kanjanapong, S., Lindbergh, C. A., La Joie, R., Strom, A., Rabinovici, G. D., Lanata, S. C., et al. (2020) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring · doi:10.1002/dad2.12042 · Cited by 38

Can Visualization Alleviate Dichotomous Thinking? Effects of Visual Representations on the Cliff Effect

Helske, J., Helske, S., Cooper, M., Ynnerman, A., & Besancon, L. (2021) · IEEE Transactions on Visualization and Computer Graphics · doi:10.1109/tvcg.2021.3073466 · Cited by 38

Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome

Sanfilippo, P., Kim, A. J., Bhukel, A., Yoo, J., Mirshahidi, P. S., Pandey, V., Bevir, H., Yuen, A., Mirshahidi, P. S., Guo, P., et al. (2024) · Neuron · doi:10.1016/j.neuron.2023.12.014 · Cited by 36