Default mode network connectivity as a predictor of post‐traumatic stress disorder symptom severity in acutely traumatized subjects
Abstract
Objective: The goal of this study was to investigate the relationship between default mode network connectivity and the severity of post‐traumatic stress disorder (PTSD) symptoms in a sample of eleven acutely traumatized subjects. Method: Participants underwent a 5.5 min resting functional magnetic resonance imaging scan. Brain areas whose activity positively correlated with that of the posterior cingulate/precuneus (PCC) were assessed. To assess the relationship between severity of PTSD symptoms and PCC connectivity, the contrast image representing areas positively correlated with the PCC was correlated with the subjects’ Clinician Administered PTSD Scale scores. Results: Results suggest that resting state connectivity of the PCC with the perigenual anterior cingulate and the right amygdala is associated with current PTSD symptoms and that correlation with the right amygdala predicts future PTSD symptoms. Conclusion: These results may contribute to the development of prognostic tools to distinguish between those who will and those who will not develop PTSD.
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Recent studies have reported alterations in subcortical and default network connectivity in individuals with PTSD.
“Recent studies have begun to investigate resting-state connectivity in individuals with PTSD and have reported alterations in subcortical31 and default network connectivity.32–35”
From Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder (2012) · cites this paper as [33]
In a more recent study with acutely traumatized individuals, PCC/precuneus-to-amygdala connectivity was found to be positively correlated with PTSD symptoms.
“however, in a more recent study with acutely traumatized individuals, they found PCC/precuneus-to-amygdala connectivity to be positively correlated with PTSD symptoms.33”
From Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder (2012) · cites this paper as [33]
Cites
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032 · see citing works
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139 · see citing works
A default mode of brain function
Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190 · see citing works
Posttraumatic Stress Disorder in the National Comorbidity Survey
Kessler, R. C. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950240066012 · Cited by 10,379 · see citing works
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C., & Raichle, M. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504136102 · Cited by 8,553 · see citing works
Functional connectivity in the resting brain: a network analysis of the default mode hypothesis
Greicius, M. D., Krasnow, B., Reiss, A. L., & Menon, V. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0135058100 · Cited by 6,358 · see citing works
The precuneus: a review of its functional anatomy and behavioural correlates
Cavanna, A. E., & Trimble, M. R. (2006) · Brain · doi:10.1093/brain/awl004 · Cited by 5,128 · see citing works
Maldjian, J. A., Laurienti, P. J., Kraft, R., & Burdette, J. H. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00169-1 · Cited by 5,066 · see citing works
The development of a Clinician-Administered PTSD Scale
Blake, D. D., Weathers, F. W., Nagy, L. M., Kaloupek, D. G., Gusman, F. D., Charney, D. S., & Keane, T. M. (1995) · Journal of Traumatic Stress · doi:10.1002/jts.2490080106 · Cited by 5,024 · see citing works
Development, reliability, and validity of a dissociation scale
BERNSTEIN, E. M., & PUTNAM, F. W. (1986) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198612000-00004 · Cited by 3,793 · cited 1× · see citing works
“In addition, participants were assessed with the Beck Depression and Anxiety Inventories (27) and the Dissociative Experiences Scale (DES) on the day of the scan (28).”
MethodGreicius, M. D., Srivastava, G., Reiss, A. L., & Menon, V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308627101 · Cited by 3,684 · see citing works
Etkin, A., & Wager, T. D. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07030504 · Cited by 3,391 · cited 6× · see citing works
“In contrast, awareness of emotional stimulation may engage top–down reflexive or effortful emotion regulation that may be impaired in PTSD as a consequence of task-related subgenual ACC ⁄ventromedial PFC hypoactivity (22).”
BackgroundMethodResultInfluentialSearching for a baseline: Functional imaging and the resting human brain
Gusnard, D. A., & Raichle, M. E. (2001) · Nature Reviews Neuroscience · doi:10.1038/35094500 · Cited by 3,371 · see citing works
Buckner, R. L., & Carroll, D. C. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2006.11.004 · Cited by 2,691 · see citing works
Greicius, M. D., Flores, B. H., Menon, V., Glover, G. H., Solvason, H. B., Kenna, H., Reiss, A. L., & Schatzberg, A. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.020 · Cited by 2,214 · see citing works
Intrinsic functional architecture in the anaesthetized monkey brain
Vincent, J. L., Patel, G. H., Fox, M. D., Snyder, A. Z., Baker, J. T., Van Essen, D. C., Zempel, J. M., Snyder, L. H., Corbetta, M., & Raichle, M. E. (2007) · Nature · doi:10.1038/nature05758 · Cited by 1,786 · see citing works
Fransson, P. (2005) · Human Brain Mapping · doi:10.1002/hbm.20113 · Cited by 1,388 · see citing works
Birn, R. M., Diamond, J. B., Smith, M. A., & Bandettini, P. A. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.02.048 · Cited by 1,343 · see citing works
fMRI resting state networks define distinct modes of long-distance interactions in the human brain
De Luca, M., Beckmann, C. F., De Stefano, N., Matthews, P. M., & Smith, S. M. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.08.035 · Cited by 1,241 · see citing works
Fransson, P., & Marrelec, G. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.05.059 · Cited by 1,213 · cited 1× · see citing works
“The posterior cingulate ⁄precuneus was chosen as the primary seed region for the investigation of default mode network connectivity, because: i) it is the region that shows the highest resting state brain metabolism (16), ii) it has most commonly been used as a seed region in prior studies of the default mode network,…”
MethodAberrant “Default Mode” Functional Connectivity in Schizophrenia
Garrity, A. G., Pearlson, G. D., McKiernan, K., Lloyd, D., Kiehl, K. A., & Calhoun, V. D. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.3.450 · Cited by 1,114 · see citing works
Ghashghaei, H. T., Hilgetag, C. C., & Barbas, H. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2006.09.046 · Cited by 845 · see citing works
Functional connectivity in a baseline resting-state network in autism
Cherkassky, V. L., Kana, R. K., Keller, T. A., & Just, M. A. (2006) · NeuroReport · doi:10.1097/01.wnr.0000239956.45448.4c · Cited by 622 · see citing works
How default is the default mode of brain function?
Fransson, P. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.06.017 · Cited by 611 · see citing works
Fear extinction in rats: Implications for human brain imaging and anxiety disorders
Milad, M. R., Rauch, S. L., Pitman, R. K., & Quirk, G. J. (2006) · Biological Psychology · doi:10.1016/j.biopsycho.2006.01.008 · Cited by 597 · see citing works
Calhoun, V. D., Kiehl, K. A., & Pearlson, G. D. (2008) · Human Brain Mapping · doi:10.1002/hbm.20581 · Cited by 567 · see citing works
Bluhm, R. L., Miller, J., Lanius, R. A., Osuch, E. A., Boksman, K., Neufeld, R. W. J., Théberge, J., Schaefer, B., & Williamson, P. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm052 · Cited by 562 · see citing works
Self-citationVogt, B. A., & Laureys, S. (2005) · Progress in brain research · doi:10.1016/s0079-6123(05)50015-3 · Cited by 497 · see citing works
Cytology and functionally correlated circuits of human posterior cingulate areas
Vogt, B. A., Vogt, L., & Laureys, S. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.07.048 · Cited by 484 · see citing works
Bluhm, R. L., Williamson, P. C., Osuch, E. A., Frewen, P. A., Stevens, T. K., Boksman, K., Neufeld, R. W. J., Théberge, J., & Lanius, R. A. (2009) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0925 · Cited by 422 · see citing works
Self-citationAcute stress disorder scale: A self-report measure of acute stress disorder.
Bryant, R. A., Moulds, M. L., & Guthrie, R. M. (2000) · Psychological Assessment · doi:10.1037/1040-3590.12.1.61 · Cited by 418 · see citing works
Goodrich, S. M. (1995) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(95)90252-x · Cited by 255 · see citing works
Bryant, R. A., Kemp, A. H., Felmingham, K. L., Liddell, B. J., Olivieri, G., Peduto, A. J., Gordon, E., & Williams, L. M. (2007) · Human Brain Mapping · doi:10.1002/hbm.20415 · Cited by 251 · see citing works
Effect of prior cognitive state on resting state networks measured with functional connectivity
Waites, A. B., Stanislavsky, A., Abbott, D. F., & Jackson, G. D. (2004) · Human Brain Mapping · doi:10.1002/hbm.20069 · Cited by 244 · see citing works
Esposito, F., Bertolino, A., Scarabino, T., Latorre, V., Blasi, G., Popolizio, T., Tedeschi, G., Cirillo, S., Goebel, R., & Salle, F. D. (2006) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2006.06.012 · Cited by 235 · see citing works
Default mode network connectivity: effects of age, sex, and analytic approach
Bluhm, R. L., Osuch, E. A., Lanius, R. A., Boksman, K., Neufeld, R. W. J., Théberge, J., & Williamson, P. (2008) · Neuroreport · doi:10.1097/wnr.0b013e328300ebbf · Cited by 222 · see citing works
Self-citationAssessing acute stress disorder: Psychometric properties of a structured clinical interview.
Bryant, R. A., Harvey, A. G., Dang, S. T., & Sackville, T. (1998) · Psychological Assessment · doi:10.1037/1040-3590.10.3.215 · Cited by 207 · see citing works
Mining the posterior cingulate: Segregation between memory and pain components
Nielsen, F. Å., Balslev, D., & Hansen, L. K. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.04.034 · Cited by 185 · see citing works
Task-induced deactivation of midline cortical regions in schizophrenia assessed with fMRI
Harrison, B. J., Yücel, M., Pujol, J., & Pantelis, C. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2006.12.027 · Cited by 166 · see citing works
Decomposing Intra-Subject Variability in Children with Attention-Deficit/Hyperactivity Disorder
Di Martino, A., Ghaffari, M., Curchack, J., Reiss, P., Hyde, C., Vannucci, M., Petkova, E., Klein, D. F., & Castellanos, F. X. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.03.008 · Cited by 146 · see citing works
Bryant, R. A., Creamer, M. C., O'Donnell, M. L., Silove, D. M., & McFARLANE, A. C. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0606 · Cited by 82 · see citing works
Horowitz, H. W. (2008) · JAMA · doi:10.1001/jama.299.5.497 · Cited by 4 · see citing works
Shulman, S. T. (2007) · Pediatric Annals · doi:10.3928/0090-4481-20070401-01 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Kim, M. J., Loucks, R. A., Palmer, A. L., Brown, A. C., Solomon, K. M., Marchante, A. N., & Whalen, P. J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.04.025 · Cited by 838 · see citing works
Childhood maltreatment, emotional dysregulation, and psychiatric comorbidities
Dvir, Y., Ford, J. D., Hill, M., & Frazier, J. A. (2014) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000014 · Cited by 698 · see citing works
Boyd, J. E., Lanius, R. A., & McKinnon, M. C. (2018) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.170021 · Cited by 407 · see citing works
Self-citationSripada, R. K., King, A. P., Welsh, R. C., Garfinkel, S. N., Wang, X., Sripada, C. S., & Liberzon, I. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318273bf33 · Cited by 412 · see citing works
O'Doherty, D. C. M., Chitty, K. M., Saddiqui, S., Bennett, M. R., & Lagopoulos, J. (2015) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2015.01.002 · Cited by 375 · see citing works
Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder
Sripada, R. K., King, A. P., Garfinkel, S. N., Wang, X., Sripada, C. S., Welsh, R. C., & Liberzon, I. (2012) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.110069 · Cited by 352 · see citing works
Koch, S. B. J., van Zuiden, M., Nawijn, L., Frijling, J. L., Veltman, D. J., & Olff, M. (2016) · Depression and Anxiety · doi:10.1002/da.22478 · Cited by 334 · see citing works
Stevens, J. S., Jovanovic, T., Fani, N., Ely, T. D., Glover, E. M., Bradley, B., & Ressler, K. J. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.05.031 · Cited by 293 · see citing works
Functional neuroimaging studies of post-traumatic stress disorder
Hughes, K. C., & Shin, L. M. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.10.198 · Cited by 290 · see citing works
Taren, A. A., Gianaros, P. J., Greco, C. M., Lindsay, E. K., Fairgrieve, A., Brown, K. W., Rosen, R. K., Ferris, J. L., Julson, E., Marsland, A. L., et al. (2015) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsv066 · Cited by 236 · see citing works
King, A. P., Block, S. R., Sripada, R. K., Rauch, S., Giardino, N., Favorite, T., Angstadt, M., Kessler, D., Welsh, R., & Liberzon, I. (2016) · Depression and Anxiety · doi:10.1002/da.22481 · Cited by 225 · see citing works
Altered amygdala resting-state functional connectivity in post-traumatic stress disorder
Rabinak, C. A., Angstadt, M., Welsh, R. C., Kenndy, A. E., Lyubkin, M., Martis, B., & Phan, K. L. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00062 · Cited by 230 · see citing works
Graham, A. M., Rasmussen, J. M., Entringer, S., Ben Ward, E., Rudolph, M. D., Gilmore, J. H., Styner, M., Wadhwa, P. D., Fair, D. A., & Buss, C. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.06.023 · Cited by 203 · see citing works
Akiki, T. J., Averill, C. L., Wrocklage, K. M., Scott, J. C., Averill, L. A., Schweinsburg, B., Alexander-Bloch, A., Martini, B., Southwick, S. M., Krystal, J. H., et al. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.05.005 · Cited by 188 · see citing works
Nicholson, A. A., Densmore, M., Frewen, P. A., Théberge, J., Neufeld, R. W., McKinnon, M. C., & Lanius, R. A. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.79 · Cited by 180 · see citing works
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Tursich, M., Ros, T., Frewen, P. A., Kluetsch, R. C., Calhoun, V. D., & Lanius, R. A. (2015) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12387 · Cited by 148 · see citing works
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Wolf, R. C., Sambataro, F., Vasic, N., Schmid, M., Thomann, P. A., Bienentreu, S. D., & Wolf, N. D. (2011) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.100150 · Cited by 130 · see citing works
Koch, S. B. J., van Zuiden, M., Nawijn, L., Frijling, J. L., Veltman, D. J., & Olff, M. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.11.018 · Cited by 123 · see citing works
Shou, H., Yang, Z., Satterthwaite, T. D., Cook, P. A., Bruce, S. E., Shinohara, R. T., Rosenberg, B., & Sheline, Y. I. (2017) · NeuroImage: Clinical · doi:10.1016/j.nicl.2017.01.030 · Cited by 108 · see citing works
Neural contributors to trauma resilience: a review of longitudinal neuroimaging studies
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Li, M.-Y., Huang, M.-M., Li, S.-Z., Tao, J., Zheng, G.-H., & Chen, L.-D. (2017) · International Journal of Neuroscience · doi:10.1080/00207454.2016.1212855 · Cited by 109 · see citing works
Thomaes, K., Dorrepaal, E., Draijer, N., de Ruiter, M. B., Elzinga, B. M., Sjoerds, Z., van Balkom, A. J., Smit, J. H., & Veltman, D. J. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsr084 · Cited by 103 · see citing works
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Engdahl, B., Leuthold, A. C., Tan, H.-R. M., Lewis, S. M., Winskowski, A. M., Dikel, T. N., & Georgopoulos, A. P. (2010) · Journal of Neural Engineering · doi:10.1088/1741-2560/7/6/066005 · Cited by 97 · see citing works
Qin, L.-D., Wang, Z., Sun, Y.-W., Wan, J.-Q., Su, S.-S., Zhou, Y., & Xu, J.-R. (2012) · Brain Research · doi:10.1016/j.brainres.2012.09.029 · Cited by 91 · see citing works
Zhou, Y., Wang, Z., Qin, L.-D., Wan, J.-Q., Sun, Y.-W., Su, S.-S., Ding, W.-N., & Xu, J.-R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046833 · Cited by 89 · see citing works
Early life stress is associated with default system integrity and emotionality during infancy
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Nardo, D., Högberg, G., Flumeri, F., Jacobsson, H., Larsson, S. A., Hällström, T., & Pagani, M. (2011) · Psychological Medicine · doi:10.1017/s0033291711000912 · Cited by 41 · see citing works
Monsa, R., Peer, M., & Arzy, S. (2018) · European Journal of Neurology · doi:10.1111/ene.13613 · Cited by 37 · see citing works
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Self-citationKearney, B. E., Corrigan, F. M., Frewen, P. A., Nevill, S., Harricharan, S., Andrews, K., Jetly, R., McKinnon, M. C., & Lanius, R. A. (2023) · European Journal of Psychotraumatology · doi:10.1080/20008066.2023.2240691 · Cited by 23 · see citing works
Self-citation
- Authors
- Lanius, R. A., Bluhm, R. L., Coupland, N. J., Hegadoren, K. M., Rowe, B., Théberge, J., Neufeld, R. W. J., Williamson, P. C., & Brimson, M.
- Affiliations
- Western University (CA)
- University of Alberta (CA)
- Corresponding author
- Lanius, R. A.
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 2009-12-14
- Volume
- 121
- Issue
- 1
- Pages
- 33-40
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W1779481146
- Cited by
- 273
- References
- 43
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 4 · 2023: 16 · 2022: 12 · 2021: 15 · 2020: 19 · 2019: 9 · 2018: 21 · 2017: 21 · 2016: 23 · 2015: 28 · 2014: 25 · 2013: 23 · 2012: 19
- FWCI
- 15.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Psychiatrica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Workplace Safety and Insurance Board
- Canadian Institutes of Health Research
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Keywords
- default mode network, post-traumatic stress disorder, PTSD symptom severity, acute trauma, resting-state functional connectivity, posterior cingulate cortex, precuneus, pregenual anterior cingulate cortex, amygdala, Clinician-Administered PTSD Scale
- MeSH terms
- Adult, Amygdala, Female, Gyrus Cinguli, Humans, Image Processing, Computer-Assisted, Functional Laterality, Life Change Events, Magnetic Resonance Imaging, Male, Neural Pathways, Probability, Prognosis, Psychiatric Status Rating Scales, Rest, Severity of Illness Index, Stress Disorders, Post-Traumatic
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