Cited by 40Non-Invasive Vital Sign MonitoringOptical Imaging and Spectroscopy TechniquesHeart Rate Variability and Autonomic Control

Reducing motion artifacts in photoplethysmograms by using relative sensor motion: Phantom study

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Wijshoff, Ralph W. C. G. R., Mischi, Massimo, Veen, Jeroen, Van Der Lee, Alexander M.·2012·Journal of Biomedical Optics

Abstract

Currently, photoplethysmograms (PPGs) are mostly used to determine a patient's blood oxygenation and pulse rate. However, PPG morphology conveys more information about the patient's cardiovascular status. Extracting this information requires measuring clean PPG waveforms that are free of artifacts. PPGs are highly susceptible to motion, which can distort the PPG-derived data. Part of the motion artifacts are considered to result from sensor-tissue motion and sensor deformation. It is hypothesized that these motion artifacts correlate with movement of the sensor with respect to the skin. This hypothesis has been proven true in a laboratory setup. In vitro PPGs have been measured in a skin perfusion phantom that is illuminated by a laser diode. Optical motion artifacts are generated in the PPG by translating the laser diode with respect to the PPG photodiode. The optical motion artifacts have been reduced significantly in vitro, by using a normalized least-mean-square algorithm with only a single coefficient that uses the laser's displacement as a reference for the motion artifacts. Laser displacement has been measured accurately via self-mixing interferometry by a compact laser diode with a ball lens integrated into the package, which can be easily integrated into a commercial sensor.

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Research works printed but not linked: 2

  1. J. Muehlsteff et al., "Phase-space representation of photoplethysmogra- phy signals as visualization concept," in Proc. BMT 2010, 44. Jahrestagung der Deutschen Gesellschaft für Biomedizinische Technik, De Gruyter, Rostock, Germany (2010).
  2. S. Kaestle, H. Block, and M. Block, "Method and apparatus for determin- ing the concentration of a component," U. S. Patent No. 6,122,535 (2000).

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Authors
Wijshoff, R. W. C. G. R., Mischi, M., Veen, J., & Van Der Lee, A. M.
Affiliations
  • Eindhoven University of Technology (NL)
  • Philips (Netherlands) (NL)
  • Philips Research
Venue
Journal of Biomedical Optics
Published
2012-11-29
Volume
17
Issue
11
Pages
1-15
ISSN
  • 1083-3668 (ISSN-L)
  • 1560-2281
OpenAlex
W2141505181
Cited by
40
References
51
Citations by year
2026: 3 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 5 · 2017: 5 · 2016: 6 · 2015: 2 · 2014: 2 · 2013: 3
FWCI
1.28
Type
journal article
Language
en
Open access
Locations
  • Journal of Biomedical Optics (publishedVersion)
  • PubMed (publishedVersion)
  • TU/e Research Portal (submittedVersion)
  • TU/e Research Portal (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Funders
IOP Photonic Devices (IPD083359)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Keywords
photoplethysmography, motion artifacts, laser displacement measurement, self-mixing interferometry, pulse rate monitoring, blood oxygenation
MeSH terms
Algorithms, Humans, Interferometry, Motion, Artifacts, Photoplethysmography, Phantoms, Imaging, Lasers, Semiconductor, Optical Phenomena, Signal-To-Noise Ratio

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