Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP

Lewis, Jada, Dickson, Dennis W., Lin, Wen-Lang, Chisholm, Louise, Corral, Anthony, Jones, Graham, Yen, Shu-Hui, Sahara, Naruhiko +6 more·2001·Science

Cited by (167)

Items 101–167 of 167

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  25. Down-regulation of WW Domain-containing Oxidoreductase Induces Tau Phosphorylation in Vitro
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  26. Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease: linkage of poorer cognitive performance to tau pathology in forebrain
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  27. Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology
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  28. Accumulation of Filamentous Tau in the Cerebral Cortex of Human Tau R406W Transgenic Mice
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  29. Disease-Modifying Therapies for Alzheimer’s Disease: More Questions than Answers
    Golde, Todd E. · 2022 · Neurotherapeutics
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  32. Phosphorylation of Tau at S422 is enhanced by Aβ in TauPS2APP triple transgenic mice
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    DeVos, Sarah L, Corjuc, Bianca T, Commins, Caitlin, Dujardin, Simon, Bannon, Riley N, Corjuc, Diana, Moore, Benjamin D, Bennett, Rachel E, Jorfi, Mehdi, Gonzales, Jose A et al. · 2018 · Brain
  35. Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity
    Ando, Kanae, Maruko-Otake, Akiko, Ohtake, Yosuke, Hayashishita, Motoki, Sekiya, Michiko, Iijima, Koichi M. · 2016 · PLOS Genetics
  36. Anti-Amyloid Therapies for Alzheimer’s Disease and the Amyloid Cascade Hypothesis
    Fedele, Ernesto · 2023 · International Journal of Molecular Sciences
  37. Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Aβ(1-42): Implications for Alzheimer’s Disease
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  38. In Vivo Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107: Preclinical Considerations in Alzheimer's Disease
    Bitner, R. Scott, Bunnelle, William H., Decker, Michael W., Drescher, Karla U., Kohlhaas, Kathy L., Markosyan, Stella, Marsh, Kennan C., Nikkel, Arthur L., Browman, Kaitlin, Radek, Rich et al. · 2010 · The Journal of Pharmacology and Experimental Therapeutics
  39. Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease
    Chabrier, Meredith A., Cheng, David, Castello, Nicholas A., Green, Kim N., LaFerla, Frank M. · 2014 · Neurobiology of Disease
  40. CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer’s Disease
    Shentu, Yang-Ping, Huo, Yuda, Feng, Xiao-Long, Gilbert, James, Zhang, Qing, Liuyang, Zhen-Yu, Wang, Xiu-Lian, Wang, Guan, Zhou, Huan, Wang, Xiao-Chuan et al. · 2018 · Cell Reports
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  45. Activation of PAR-1 Kinase and Stimulation of Tau Phosphorylation by Diverse Signals Require the Tumor Suppressor Protein LKB1
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  58. Selective vulnerability of different types of commissural neurons for amyloid  -protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology
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