Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

RNA granules

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Liquid-Liquid Phase Separation in Biology

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Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

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Coactivator condensation at super-enhancers links phase separation and gene control

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Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

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Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

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LNCcation: lncRNA localization and function

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The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

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Tau protein liquid–liquid phase separation can initiate tau aggregation

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A framework for understanding the functions of biomolecular condensates across scales

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RNA phase transitions in repeat expansion disorders

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α‐Synuclein aggregation nucleates through liquid‐liquid phase separation

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Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau

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Eukaryotic core promoters and the functional basis of transcription initiation

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A brief history of autophagy from cell biology to physiology and disease

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Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder

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Molecular interactions underlying liquid‐liquid phase separation of the FUS low‐complexity domain

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Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome

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Developmental enhancers and chromosome topology

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RNA transcription modulates phase transition-driven nuclear body assembly

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Phase separation and neurodegenerative diseases: a disturbance in the force

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Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

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Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity

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Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase

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Mechanisms of Selective Autophagy

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Relationship of sequence and phase separation in protein low-complexity regions

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Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors

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RNA-Based Coacervates as a Model for Membraneless Organelles: Formation, Properties, and Interfacial Liposome Assembly

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Active coacervate droplets as a model for membraneless organelles and protocells

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Phase separation at the synapse

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Spatiotemporal regulation of liquid-like condensates in epigenetic inheritance

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Suppression of Ostwald ripening in active emulsions

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Development and dynamics of cell polarity at a glance

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Conformational Dynamics of Intrinsically Disordered Proteins Regulate Biomolecular Condensate Chemistry

Abyzov, A., Blackledge, M., & Zweckstetter, M. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00774 · Cited by 215

Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli

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Reversible generation of coacervate droplets in an enzymatic network

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RNA transport and local translation in neurodevelopmental and neurodegenerative disease

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Twenty Years of SynGAP Research: From Synapses to Cognition

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Metabolic Inputs into the Epigenome

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Surface electrostatics govern the emulsion stability of biomolecular condensates

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Polyamine/Nucleotide Coacervates Provide Strong Compartmentalization of Mg 2+ , Nucleotides, and RNA

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Sustained enzymatic activity and flow in crowded protein droplets

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Making the Case for Disordered Proteins and Biomolecular Condensates in Bacteria

Cohan, M. C., & Pappu, R. V. (2020) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2020.04.011 · Cited by 104

Thermodynamic forces from protein and water govern condensate formation of an intrinsically disordered protein domain

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Chemical-Reaction-Controlled Phase Separated Drops: Formation, Size Selection, and Coarsening

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De-centralizing the Central Dogma: mRNA translation in space and time

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Disentangling the complexity of low complexity proteins

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C. elegans germ cells show temperature and age-dependent expression of Cer1, a Gypsy/Ty3-related retrotransposon

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Liquid-liquid phase separation of protein tau: An emerging process in Alzheimer's disease pathogenesis

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Integration of Data from Liquid–Liquid Phase Separation Databases Highlights Concentration and Dosage Sensitivity of LLPS Drivers

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Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function

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Complex coacervates as artificial membraneless organelles and protocells

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Homotypic RNA clustering accompanies a liquid-to-solid transition inside the core of multi-component biomolecular condensates

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GENESIS CGDYN: large-scale coarse-grained MD simulation with dynamic load balancing for heterogeneous biomolecular systems

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Nuclear speckle proteins form intrinsic and MALAT1-dependent microphases

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Aggregation and disaggregation features of the human proteome

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Liquid-liquid phase separation in Alzheimer’s disease

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Tau liquid–liquid phase separation: At the crossroads of tau physiology and tauopathy

Islam, M., Shen, F., Regmi, D., Petersen, K., Karim, M. R. U., & Du, D. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.30853 · Cited by 28

The Chromatin Regulator HMGA1a Undergoes Phase Separation in the Nucleus**

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Enzymatic control over coacervation

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Decoding Missense Variants by Incorporating Phase Separation via Machine Learning

Feng, M., Wei, X., Zheng, X., Liu, L., Lin, L., Xia, M., He, G., Shi, Y., & Lu, Q. (2024) · Nature Communications · doi:10.1038/s41467-024-52580-3 · Cited by 15

Fused in sarcoma undergoes cold denaturation: Implications for phase separation

Félix, S. S., Laurents, D. V., Oroz, J., & Cabrita, E. J. (2023) · Protein Science · doi:10.1002/pro.4521 · Cited by 12

Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo

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The Rous sarcoma virus Gag Polyprotein Forms Biomolecular Condensates Driven by Intrinsically-disordered Regions

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The synaptonemal complex aligns meiotic chromosomes by wetting

Gordon, S. G., Rodriguez, A. A., Gu, Y., Corbett, K. D., Lee, C. F., & Rog, O. (2025) · Science Advances · doi:10.1126/sciadv.adt5675 · Cited by 9

BR-bodies facilitate adaptive responses and survival during copper stress in Caulobacter crescentus

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Aurora A regulates the material property of spindle poles to orchestrate nuclear organization at mitotic exit

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The role of N-terminal acetylation on biomolecular condensation

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Decoding Missense Variants by Incorporating Phase Separation via Machine Learning

Feng, M., Wei, X., Zheng, X., Liu, L., Lin, L., Xia, M., He, G., Shi, Y., & Lu, Q. (2024) · doi:10.1101/2024.04.01.587546

Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegans

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