A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine
Wallace, Douglas C.·2005·Annual Review of Genetics
Cited by (159)
Items 101–159 of 159
- Stimulated Human Mast Cells Secrete Mitochondrial Components That Have Autocrine and Paracrine Inflammatory ActionsZhang, Bodi, Asadi, Shahrzad, Weng, Zuyi, Sismanopoulos, Nikolaos, Theoharides, Theoharis C. · 2012 · PLoS ONE
- Genetic Determinants of Human Health Span and Life Span: Progress and
New OpportunitiesMartin, George M, Bergman, Aviv, Barzilai, Nir · 2007 · PLoS Genetics
- <i>Drosophila</i>
Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activityRahman, Motiur, Nirala, Niraj K., Singh, Alka, Zhu, Lihua Julie, Taguchi, Kaori, Bamba, Takeshi, Fukusaki, Eiichiro, Shaw, Leslie M., Lambright, David G., Acharya, Jairaj K. et al. · 2014 · Journal of Cell Biology
- Metabolic features and regulation in cell senescenceKwon, So Mee, Hong, Sun Mi, Lee, Young-Kyoung, Min, Seongki, Yoon, Gyesoon · 2019 · BMB Reports
- Mitochondrial DNA haplogroups: Role in the prevalence and severity of knee osteoarthritisRego‐Pérez, Ignacio, Fernández‐Moreno, Mercedes, Fernández‐López, Carlos, Arenas, Joaquín, Blanco, Francisco J. · 2008 · Arthritis & Rheumatism
- Mitochondrial signaling, TOR, and life spanSchieke, Stefan M., Finkel, Toren · 2006 · Biological Chemistry
- Mouse models of age-related macular degenerationElizabeth Rakoczy, P., Yu, Meaghan J.T., Nusinowitz, Steven, Chang, Bo, Heckenlively, John R. · 2006 · Experimental Eye Research
- Hypersensitivity to oxygen and shortened lifespan in a
<i>Drosophila</i>
mitochondrial complex II mutantWalker, David W., Hájek, Petr, Muffat, Julien, Knoepfle, Dan, Cornelison, Stephanie, Attardi, Giuseppe, Benzer, Seymour · 2006 · Proceedings of the National Academy of Sciences
- Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restrictionFinley, Lydia W. S., Lee, Jaewon, Souza, Amanda, Desquiret-Dumas, Valérie, Bullock, Kevin, Rowe, Glenn C., Procaccio, Vincent, Clish, Clary B., Arany, Zoltan, Haigis, Marcia C. · 2012 · Proceedings of the National Academy of Sciences
- Prophylaxis of migraine headaches with riboflavin: A systematic reviewThompson, D. F., Saluja, H. S. · 2017 · Journal of Clinical Pharmacy and Therapeutics
- Defective Autophagy and mTORC1 Signaling in Myotubularin Null MiceFetalvero, Kristina M., Yu, Yenyen, Goetschkes, Margaret, Liang, Guiqing, Valdez, Reginald A., Gould, Ty, Triantafellow, Ellen, Bergling, Sebastian, Loureiro, Joseph, Eash, John et al. · 2013 · Molecular and Cellular Biology
- The Mitochondrial Permeability Transition Pore Regulates Nitric Oxide-Mediated Apoptosis of Neurons Induced by Target DeprivationMartin, Lee J., Adams, Neal A., Pan, Yan, Price, Ann, Wong, Margaret · 2011 · The Journal of Neuroscience
- Mitochondrial Dysfunctions: A Red Thread across Neurodegenerative DiseasesStanga, Serena, Caretto, Anna, Boido, Marina, Vercelli, Alessandro · 2020 · International Journal of Molecular Sciences
- Aup1-mediated regulation of Rtg3 during mitophagyJourno, Dikla, Mor, Angelika, Abeliovich, Hagai · 2009 · Journal of Biological Chemistry
- Mitochondrial Oxidative and Nitrosative Stress and Alzheimer DiseaseButterfield, D. Allan, Boyd-Kimball, Debra · 2020 · Antioxidants
- Mitochondrial Dysfunction in Skeletal Muscle PathologiesAbrigo, Johanna, Simon, Felipe, Cabrera, Daniel, Vilos, Cristian, Cabello-Verrugio, Claudio · 2019 · Current Protein & Peptide Science
- Mitochondrial dysfunction in CA1 hippocampal neurons of the UBE3A deficient mouse model for Angelman syndromeSu, Hailing, Fan, Weiwei, Coskun, Pinar E., Vesa, Jouni, Gold, June-Anne, Jiang, Yong-Hui, Potluri, Prasanth, Procaccio, Vincent, Acab, Allan, Weiss, John H. et al. · 2011 · Neuroscience Letters
- ABC transporter‐mediated release of a haem chaperone allows cytochrome <i>c</i> biogenesisFeissner, Robert E., Richard‐Fogal, Cynthia L., Frawley, Elaine R., Kranz, Robert G. · 2006 · Molecular Microbiology
- Complementary RNA and Protein Profiling Identifies Iron as a Key Regulator of Mitochondrial BiogenesisRensvold, Jarred W., Ong, Shao-En, Jeevananthan, Athavi, Carr, Steven A., Mootha, Vamsi K., Pagliarini, David J. · 2013 · Cell Reports
- Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progressionChaube, Balkrishna, Malvi, Parmanand, Singh, Shivendra Vikram, Mohammad, Naoshad, Meena, Avtar Singh, Bhat, Manoj Kumar · 2015 · Oncotarget
- Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseasesCai, Na, Gomez-Duran, Aurora, Yonova-Doing, Ekaterina, Kundu, Kousik, Burgess, Annette I., Golder, Zoe J., Calabrese, Claudia, Bonder, Marc J., Camacho, Marta, Lawson, Rachael A. et al. · 2021 · Nature Medicine
- Age-related neuronal loss in the rat brain starts at the end of adolescenceMorterá, Priscilla, Herculano-Houzel, Suzana · 2012 · Frontiers in Neuroanatomy
- Role of PGC-1α in sarcopenia: Etiology and potential intervention—A mini-reviewJi, Li Li, Kang, Chounghun · 2015 · Gerontology
- Mitochondrial function and mitochondrial DNA maintenance with advancing ageGaziev, Azhub I., Abdullaev, Serzh, Podlutsky, Andrej · 2014 · Biogerontology
- Women With Mitochondrial Haplogroup N9a Are Protected Against Metabolic SyndromeTanaka, Masashi, Fuku, Noriyuki, Nishigaki, Yutaka, Matsuo, Hitoshi, Segawa, Tomonori, Watanabe, Sachiro, Kato, Kimihiko, Yoko, Kiyoshi, Ito, Masafumi, Nozawa, Yoshinori et al. · 2007 · Diabetes
- Increased mitochondrial Ca 2+ and decreased sarcoplasmic reticulum Ca 2+ in mitochondrial myopathyAydin, Jan, Andersson, Daniel C., Hänninen, Sandra L., Wredenberg, Anna, Tavi, Pasi, Park, Chan Bae, Larsson, Nils-Göran, Bruton, Joseph D., Westerblad, Håkan · 2009 · Human Molecular Genetics
- Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperaturesAli, Sameh S., Marcondes, Maria-Cecilia Garibaldi, Bajova, Hilda, Dugan, Laura L., Conti, Bruno · 2010 · Journal of Biological Chemistry
- Increased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver diseaseSong, Byoung-Joon, Abdelmegeed, Mohamed A., Henderson, Lauren E., Yoo, Seong-Ho, Wan, Jie, Purohit, Vishnudutt, Hardwick, James P., Moon, Kwan-Hoon · 2013 · Oxidative Medicine and Cellular Longevity
- Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing PeptidesThai, Phung N., Seidlmayer, Lea K., Miller, Charles, Ferrero, Maura, Dorn, Gerald W., Schaefer, Saul, Bers, Donald M., Dedkova, Elena N. · 2019 · Frontiers in Physiology
- An Exploratory Analysis of the Effects of a Weight Loss Plus Exercise Program on Cellular Quality Control Mechanisms in Older Overweight WomenWohlgemuth, Stephanie E., Lees, Hazel A., Marzetti, Emanuele, Manini, Todd M., Aranda, Juan M., Daniels, Michael J., Pahor, Marco, Perri, Michael G., Leeuwenburgh, Christian, Anton, Stephen D. · 2011 · Rejuvenation Research
- Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistanceKenny, Helena C., Rudwill, Floriane, Breen, Laura, Salanova, Michele, Blottner, Dieter, Heise, Tim, Heer, Martina, Blanc, Stephane, O’Gorman, Donal J. · 2017 · Diabetologia
- Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolismPei, Liming, Mu, Yangling, Leblanc, Mathias, Alaynick, William, Barish, Grant D., Pankratz, Matthew, Tseng, Tiffany W., Kaufman, Samantha, Liddle, Christopher, Yu, Ruth T. et al. · 2015 · Cell Metabolism
- A Combination of Nutriments Improves Mitochondrial Biogenesis and Function in Skeletal Muscle of Type 2 Diabetic Goto–Kakizaki RatsShen, Weili, Hao, Jiejie, Tian, Chuan, Ren, Jinmin, Yang, Lu, Li, Xuesen, Luo, Cheng, Cotma, Carl W., Liu, Jiankang · 2008 · PLoS ONE
- Mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated mitochondrial dysfunction in rat liverMoon, Kwan‐Hoon, Upreti, Vijay V., Yu, Li‐Rong, Lee, Insong J., Ye, Xiaoying, Eddington, Natalie D., Veenstra, Timothy D., Song, Byoung‐Joon · 2008 · PROTEOMICS
- Nuclear and mitochondrial DNA oxidation in Alzheimer's diseaseSantos, Renato X., Correia, Sónia C., Zhu, Xiongwei, Lee, Hyoung-Gon, Petersen, Robert B., Nunomura, Akihiko, Smith, Mark A., Perry, George, Moreira, Paula I. · 2012 · Free Radical Research
- C. elegans as a model organism for human mitochondrial associated disordersMaglioni, Silvia, Ventura, Natascia · 2016 · Mitochondrion
- Engineering the alternative oxidase gene to better understand and counteract mitochondrial defects: state of the art and perspectivesEl‐Khoury, Riyad, Kemppainen, Kia K, Dufour, Eric, Szibor, Marten, Jacobs, Howard T, Rustin, Pierre · 2014 · British Journal of Pharmacology
- Actions of 17β-estradiol and testosterone in the mitochondria and their implications in agingVasconsuelo, Andrea, Milanesi, Lorena, Boland, Ricardo · 2013 · Ageing Research Reviews
- Prolonged exposure to insulin suppresses mitochondrial production in primary hepatocytes.Liu, Hui-Yu, Yehuda-Shnaidman, Einav, Hong, Tao, Han, Jianmin, Pi, Jingbo, Liu, Zhenqi, Cao, Wenhong · 2009 · Journal of Biological Chemistry
- Renal mitochondrial impairment is attenuated by AT
<sub>1</sub>
blockade in experimental Type I diabetesde Cavanagh, Elena M. V., Ferder, León, Toblli, Jorge E., Piotrkowski, Bárbara, Stella, Inés, Fraga, Cesar G., Inserra, Felipe · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
- Could mitochondrial efficiency explain the susceptibility to adiposity, metabolic syndrome, diabetes and cardiovascular diseases in South Asian populations?Bhopal, R. S, Rafnsson, S. B · 2009 · International Journal of Epidemiology
- Mitochondrial Chaperones in the Brain: Safeguarding Brain Health and Metabolism?Castro, José Pedro, Wardelmann, Kristina, Grune, Tilman, Kleinridders, André · 2018 · Frontiers in Endocrinology
- Mitochondria, motor neurons and agingGarcía, M.L., Fernández, A., Solas, M.T. · 2013 · Journal of the Neurological Sciences
- Effects of post-exercise recovery in a cold environment on muscle glycogen, PGC-1α, and downstream transcription factorsSlivka, Dustin, Heesch, Matthew, Dumke, Charles, Cuddy, John, Hailes, Walter, Ruby, Brent · 2013 · Cryobiology
- mtDNA mutations in human aging and longevity: controversies and new perspectives opened by high-throughput technologiesSevini, Federica, Giuliani, Cristina, Vianello, Dario, Giampieri, Enrico, Santoro, Aurelia, Biondi, Fiammetta, Garagnani, Paolo, Passarino, Giuseppe, Luiselli, Donata, Capri, Miriam et al. · 2014 · Experimental Gerontology
- Metabolic reprogramming: a bridge between aging and tumorigenesisDrapela, Stanislav, Ilter, Didem, Gomes, Ana P. · 2022 · Molecular Oncology
- Perinatal exposure to nicotine and implications for subsequent obstructive lung diseaseMaritz, Gert S. · 2013 · Paediatric Respiratory Reviews
- Endogenous Ovarian Hormones Affect Mitochondrial Efficiency in Cerebral Endothelium via Distinct Regulation of PGC-1 IsoformsKemper, Martin F, Zhao, Yuanzi, Duckles, Sue P, Krause, Diana N · 2013 · Journal of Cerebral Blood Flow & Metabolism
- Biallelic mutations in FDXR cause neurodegeneration associated with inflammationSlone, Jesse, Peng, Yanyan, Chamberlin, Adam, Harris, Belinda, Kaylor, Julie, McDonald, Marie T., Lemmon, Monica, El-Dairi, Mays Antonine, Tchapyjnikov, Dmitry, Gonzalez-Krellwitz, Laura A et al. · 2018 · Journal of Human Genetics
- Alteration of mtDNA copy number, mitochondrial gene expression and extracellular DNA content in mice after irradiation at lethal doseEvdokimovsky, Edward V., Ushakova, Tatjana E., Kudriavtcev, Andrej A., Gaziev, Ajub. I. · 2011 · Radiation and Environmental Biophysics
- Regulation of PPAR<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>γ</mml:mi></mml:math>Coactivator-1<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>α</mml:mi></mml:math>Function and Expression in Muscle: Effect of ExerciseUguccioni, Giulia, D'souza, Donna, Hood, David A. · 2010 · PPAR Research
- Mutations in Two Zinc-Cluster Proteins Activate Alternative Respiratory and Gluconeogenic Pathways and Restore Senescence in Long-Lived Respiratory Mutants of<i>Podospora anserina</i>Sellem, Carole H, Bovier, Elodie, Lorin, Séverine, Sainsard-Chanet, Annie · 2009 · Genetics
- Is the use of resveratrol in the treatment and prevention of obesity premature?van der Spuy, Wendy J., Pretorius, Etheresia · 2009 · Nutrition Research Reviews
- Behavioral effects of SQSTM1/p62 overexpression in mice: Support for a mitochondrial role in depression and anxietySeibenhener, M. Lamar, Zhao, Ting, Du, Yifeng, Calderilla-Barbosa, Luis, Yan, Jin, Jiang, Jianxiong, Wooten, Marie W., Wooten, Michael C. · 2013 · Behavioural Brain Research
- Diaminodiphenyl sulfone–induced parkin ameliorates age-dependent dopaminergic neuronal lossLee, Yun-Il, Kang, Hojin, Ha, Young Wan, Chang, Ki-Young, Cho, Sung-Chun, Song, Sang Ok, Kim, Hyein, Jo, Areum, Khang, Rin, Choi, Jeong-Yun et al. · 2016 · Neurobiology of Aging
- Thyroid Hormone Transport into Cellular TissueHoltorf, Kent · 2014 · Journal of Restorative Medicine
- Young Astrocytic Mitochondria Attenuate the Elevated Level of CCL11 in the Aged Mice, Contributing to Cognitive Function ImprovementTashiro, Ryosuke, Ozaki, Dan, Bautista-Garrido, Jesus, Sun, Guanghua, Obertas, Lidiya, Mobley, Alexis S., Kim, Gab Seok, Aronowski, Jaroslaw, Jung, Joo Eun · 2023 · International Journal of Molecular Sciences
- A transgenic model to study the pathogenesis of somatic mtDNA mutation accumulation in β‐cellsBensch, K. G., DeGraaf, W., Hansen, P. A., Zassenhaus, H. P., Corbett, J. A. · 2007 · Diabetes Obesity and Metabolism
- Multifunctional nanocomposites utilizing ruthenium (II) complex/manganese (IV) dioxide nanoparticle for synergistic reinforcing radioimmunotherapyPeng, Jian, Quan, Dong-Ling, Yang, Guang, Wei, Lin-Tao, Yang, Zhuan, Dong, Zhi-Ying, Zou, Yi-Ming, Hou, Ying-Ke, Chen, Jin-Xiang, Lv, Lin et al. · 2024 · Journal of Nanobiotechnology