A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Wallace, Douglas C.·2005·Annual Review of Genetics

Cited by (159)

Items 101–159 of 159

  1. Stimulated Human Mast Cells Secrete Mitochondrial Components That Have Autocrine and Paracrine Inflammatory Actions
    Zhang, Bodi, Asadi, Shahrzad, Weng, Zuyi, Sismanopoulos, Nikolaos, Theoharides, Theoharis C. · 2012 · PLoS ONE
  2. Genetic Determinants of Human Health Span and Life Span: Progress and New Opportunities
    Martin, George M, Bergman, Aviv, Barzilai, Nir · 2007 · PLoS Genetics
  3. <i>Drosophila</i> Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity
    Rahman, Motiur, Nirala, Niraj K., Singh, Alka, Zhu, Lihua Julie, Taguchi, Kaori, Bamba, Takeshi, Fukusaki, Eiichiro, Shaw, Leslie M., Lambright, David G., Acharya, Jairaj K. et al. · 2014 · Journal of Cell Biology
  4. Metabolic features and regulation in cell senescence
    Kwon, So Mee, Hong, Sun Mi, Lee, Young-Kyoung, Min, Seongki, Yoon, Gyesoon · 2019 · BMB Reports
  5. Mitochondrial DNA haplogroups: Role in the prevalence and severity of knee osteoarthritis
    Rego‐Pérez, Ignacio, Fernández‐Moreno, Mercedes, Fernández‐López, Carlos, Arenas, Joaquín, Blanco, Francisco J. · 2008 · Arthritis &amp; Rheumatism
  6. Mitochondrial signaling, TOR, and life span
    Schieke, Stefan M., Finkel, Toren · 2006 · Biological Chemistry
  7. Mouse models of age-related macular degeneration
    Elizabeth Rakoczy, P., Yu, Meaghan J.T., Nusinowitz, Steven, Chang, Bo, Heckenlively, John R. · 2006 · Experimental Eye Research
  8. Hypersensitivity to oxygen and shortened lifespan in a <i>Drosophila</i> mitochondrial complex II mutant
    Walker, David W., Hájek, Petr, Muffat, Julien, Knoepfle, Dan, Cornelison, Stephanie, Attardi, Giuseppe, Benzer, Seymour · 2006 · Proceedings of the National Academy of Sciences
  9. Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction
    Finley, Lydia W. S., Lee, Jaewon, Souza, Amanda, Desquiret-Dumas, Valérie, Bullock, Kevin, Rowe, Glenn C., Procaccio, Vincent, Clish, Clary B., Arany, Zoltan, Haigis, Marcia C. · 2012 · Proceedings of the National Academy of Sciences
  10. Prophylaxis of migraine headaches with riboflavin: A systematic review
    Thompson, D. F., Saluja, H. S. · 2017 · Journal of Clinical Pharmacy and Therapeutics
  11. Defective Autophagy and mTORC1 Signaling in Myotubularin Null Mice
    Fetalvero, Kristina M., Yu, Yenyen, Goetschkes, Margaret, Liang, Guiqing, Valdez, Reginald A., Gould, Ty, Triantafellow, Ellen, Bergling, Sebastian, Loureiro, Joseph, Eash, John et al. · 2013 · Molecular and Cellular Biology
  12. The Mitochondrial Permeability Transition Pore Regulates Nitric Oxide-Mediated Apoptosis of Neurons Induced by Target Deprivation
    Martin, Lee J., Adams, Neal A., Pan, Yan, Price, Ann, Wong, Margaret · 2011 · The Journal of Neuroscience
  13. Mitochondrial Dysfunctions: A Red Thread across Neurodegenerative Diseases
    Stanga, Serena, Caretto, Anna, Boido, Marina, Vercelli, Alessandro · 2020 · International Journal of Molecular Sciences
  14. Aup1-mediated regulation of Rtg3 during mitophagy
    Journo, Dikla, Mor, Angelika, Abeliovich, Hagai · 2009 · Journal of Biological Chemistry
  15. Mitochondrial Oxidative and Nitrosative Stress and Alzheimer Disease
    Butterfield, D. Allan, Boyd-Kimball, Debra · 2020 · Antioxidants
  16. Mitochondrial Dysfunction in Skeletal Muscle Pathologies
    Abrigo, Johanna, Simon, Felipe, Cabrera, Daniel, Vilos, Cristian, Cabello-Verrugio, Claudio · 2019 · Current Protein &amp; Peptide Science
  17. Mitochondrial dysfunction in CA1 hippocampal neurons of the UBE3A deficient mouse model for Angelman syndrome
    Su, Hailing, Fan, Weiwei, Coskun, Pinar E., Vesa, Jouni, Gold, June-Anne, Jiang, Yong-Hui, Potluri, Prasanth, Procaccio, Vincent, Acab, Allan, Weiss, John H. et al. · 2011 · Neuroscience Letters
  18. ABC transporter‐mediated release of a haem chaperone allows cytochrome <i>c</i> biogenesis
    Feissner, Robert E., Richard‐Fogal, Cynthia L., Frawley, Elaine R., Kranz, Robert G. · 2006 · Molecular Microbiology
  19. Complementary RNA and Protein Profiling Identifies Iron as a Key Regulator of Mitochondrial Biogenesis
    Rensvold, Jarred W., Ong, Shao-En, Jeevananthan, Athavi, Carr, Steven A., Mootha, Vamsi K., Pagliarini, David J. · 2013 · Cell Reports
  20. Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression
    Chaube, Balkrishna, Malvi, Parmanand, Singh, Shivendra Vikram, Mohammad, Naoshad, Meena, Avtar Singh, Bhat, Manoj Kumar · 2015 · Oncotarget
  21. Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases
    Cai, Na, Gomez-Duran, Aurora, Yonova-Doing, Ekaterina, Kundu, Kousik, Burgess, Annette I., Golder, Zoe J., Calabrese, Claudia, Bonder, Marc J., Camacho, Marta, Lawson, Rachael A. et al. · 2021 · Nature Medicine
  22. Age-related neuronal loss in the rat brain starts at the end of adolescence
    Morterá, Priscilla, Herculano-Houzel, Suzana · 2012 · Frontiers in Neuroanatomy
  23. Role of PGC-1α in sarcopenia: Etiology and potential intervention—A mini-review
    Ji, Li Li, Kang, Chounghun · 2015 · Gerontology
  24. Mitochondrial function and mitochondrial DNA maintenance with advancing age
    Gaziev, Azhub I., Abdullaev, Serzh, Podlutsky, Andrej · 2014 · Biogerontology
  25. Women With Mitochondrial Haplogroup N9a Are Protected Against Metabolic Syndrome
    Tanaka, Masashi, Fuku, Noriyuki, Nishigaki, Yutaka, Matsuo, Hitoshi, Segawa, Tomonori, Watanabe, Sachiro, Kato, Kimihiko, Yoko, Kiyoshi, Ito, Masafumi, Nozawa, Yoshinori et al. · 2007 · Diabetes
  26. Increased mitochondrial Ca 2+ and decreased sarcoplasmic reticulum Ca 2+ in mitochondrial myopathy
    Aydin, Jan, Andersson, Daniel C., Hänninen, Sandra L., Wredenberg, Anna, Tavi, Pasi, Park, Chan Bae, Larsson, Nils-Göran, Bruton, Joseph D., Westerblad, Håkan · 2009 · Human Molecular Genetics
  27. Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperatures
    Ali, Sameh S., Marcondes, Maria-Cecilia Garibaldi, Bajova, Hilda, Dugan, Laura L., Conti, Bruno · 2010 · Journal of Biological Chemistry
  28. Increased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver disease
    Song, Byoung-Joon, Abdelmegeed, Mohamed A., Henderson, Lauren E., Yoo, Seong-Ho, Wan, Jie, Purohit, Vishnudutt, Hardwick, James P., Moon, Kwan-Hoon · 2013 · Oxidative Medicine and Cellular Longevity
  29. Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides
    Thai, Phung N., Seidlmayer, Lea K., Miller, Charles, Ferrero, Maura, Dorn, Gerald W., Schaefer, Saul, Bers, Donald M., Dedkova, Elena N. · 2019 · Frontiers in Physiology
  30. An Exploratory Analysis of the Effects of a Weight Loss Plus Exercise Program on Cellular Quality Control Mechanisms in Older Overweight Women
    Wohlgemuth, Stephanie E., Lees, Hazel A., Marzetti, Emanuele, Manini, Todd M., Aranda, Juan M., Daniels, Michael J., Pahor, Marco, Perri, Michael G., Leeuwenburgh, Christian, Anton, Stephen D. · 2011 · Rejuvenation Research
  31. Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance
    Kenny, Helena C., Rudwill, Floriane, Breen, Laura, Salanova, Michele, Blottner, Dieter, Heise, Tim, Heer, Martina, Blanc, Stephane, O’Gorman, Donal J. · 2017 · Diabetologia
  32. Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism
    Pei, Liming, Mu, Yangling, Leblanc, Mathias, Alaynick, William, Barish, Grant D., Pankratz, Matthew, Tseng, Tiffany W., Kaufman, Samantha, Liddle, Christopher, Yu, Ruth T. et al. · 2015 · Cell Metabolism
  33. A Combination of Nutriments Improves Mitochondrial Biogenesis and Function in Skeletal Muscle of Type 2 Diabetic Goto–Kakizaki Rats
    Shen, Weili, Hao, Jiejie, Tian, Chuan, Ren, Jinmin, Yang, Lu, Li, Xuesen, Luo, Cheng, Cotma, Carl W., Liu, Jiankang · 2008 · PLoS ONE
  34. Mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated mitochondrial dysfunction in rat liver
    Moon, Kwan‐Hoon, Upreti, Vijay V., Yu, Li‐Rong, Lee, Insong J., Ye, Xiaoying, Eddington, Natalie D., Veenstra, Timothy D., Song, Byoung‐Joon · 2008 · PROTEOMICS
  35. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease
    Santos, Renato X., Correia, Sónia C., Zhu, Xiongwei, Lee, Hyoung-Gon, Petersen, Robert B., Nunomura, Akihiko, Smith, Mark A., Perry, George, Moreira, Paula I. · 2012 · Free Radical Research
  36. C. elegans as a model organism for human mitochondrial associated disorders
    Maglioni, Silvia, Ventura, Natascia · 2016 · Mitochondrion
  37. Engineering the alternative oxidase gene to better understand and counteract mitochondrial defects: state of the art and perspectives
    El‐Khoury, Riyad, Kemppainen, Kia K, Dufour, Eric, Szibor, Marten, Jacobs, Howard T, Rustin, Pierre · 2014 · British Journal of Pharmacology
  38. Actions of 17β-estradiol and testosterone in the mitochondria and their implications in aging
    Vasconsuelo, Andrea, Milanesi, Lorena, Boland, Ricardo · 2013 · Ageing Research Reviews
  39. Prolonged exposure to insulin suppresses mitochondrial production in primary hepatocytes.
    Liu, Hui-Yu, Yehuda-Shnaidman, Einav, Hong, Tao, Han, Jianmin, Pi, Jingbo, Liu, Zhenqi, Cao, Wenhong · 2009 · Journal of Biological Chemistry
  40. Renal mitochondrial impairment is attenuated by AT <sub>1</sub> blockade in experimental Type I diabetes
    de Cavanagh, Elena M. V., Ferder, León, Toblli, Jorge E., Piotrkowski, Bárbara, Stella, Inés, Fraga, Cesar G., Inserra, Felipe · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
  41. Could mitochondrial efficiency explain the susceptibility to adiposity, metabolic syndrome, diabetes and cardiovascular diseases in South Asian populations?
    Bhopal, R. S, Rafnsson, S. B · 2009 · International Journal of Epidemiology
  42. Mitochondrial Chaperones in the Brain: Safeguarding Brain Health and Metabolism?
    Castro, José Pedro, Wardelmann, Kristina, Grune, Tilman, Kleinridders, André · 2018 · Frontiers in Endocrinology
  43. Mitochondria, motor neurons and aging
    García, M.L., Fernández, A., Solas, M.T. · 2013 · Journal of the Neurological Sciences
  44. Effects of post-exercise recovery in a cold environment on muscle glycogen, PGC-1α, and downstream transcription factors
    Slivka, Dustin, Heesch, Matthew, Dumke, Charles, Cuddy, John, Hailes, Walter, Ruby, Brent · 2013 · Cryobiology
  45. mtDNA mutations in human aging and longevity: controversies and new perspectives opened by high-throughput technologies
    Sevini, Federica, Giuliani, Cristina, Vianello, Dario, Giampieri, Enrico, Santoro, Aurelia, Biondi, Fiammetta, Garagnani, Paolo, Passarino, Giuseppe, Luiselli, Donata, Capri, Miriam et al. · 2014 · Experimental Gerontology
  46. Metabolic reprogramming: a bridge between aging and tumorigenesis
    Drapela, Stanislav, Ilter, Didem, Gomes, Ana P. · 2022 · Molecular Oncology
  47. Perinatal exposure to nicotine and implications for subsequent obstructive lung disease
    Maritz, Gert S. · 2013 · Paediatric Respiratory Reviews
  48. Endogenous Ovarian Hormones Affect Mitochondrial Efficiency in Cerebral Endothelium via Distinct Regulation of PGC-1 Isoforms
    Kemper, Martin F, Zhao, Yuanzi, Duckles, Sue P, Krause, Diana N · 2013 · Journal of Cerebral Blood Flow &amp; Metabolism
  49. Biallelic mutations in FDXR cause neurodegeneration associated with inflammation
    Slone, Jesse, Peng, Yanyan, Chamberlin, Adam, Harris, Belinda, Kaylor, Julie, McDonald, Marie T., Lemmon, Monica, El-Dairi, Mays Antonine, Tchapyjnikov, Dmitry, Gonzalez-Krellwitz, Laura A et al. · 2018 · Journal of Human Genetics
  50. Alteration of mtDNA copy number, mitochondrial gene expression and extracellular DNA content in mice after irradiation at lethal dose
    Evdokimovsky, Edward V., Ushakova, Tatjana E., Kudriavtcev, Andrej A., Gaziev, Ajub. I. · 2011 · Radiation and Environmental Biophysics
  51. Regulation of PPAR<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>γ</mml:mi></mml:math>Coactivator-1<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>α</mml:mi></mml:math>Function and Expression in Muscle: Effect of Exercise
    Uguccioni, Giulia, D'souza, Donna, Hood, David A. · 2010 · PPAR Research
  52. Mutations in Two Zinc-Cluster Proteins Activate Alternative Respiratory and Gluconeogenic Pathways and Restore Senescence in Long-Lived Respiratory Mutants of<i>Podospora anserina</i>
    Sellem, Carole H, Bovier, Elodie, Lorin, Séverine, Sainsard-Chanet, Annie · 2009 · Genetics
  53. Is the use of resveratrol in the treatment and prevention of obesity premature?
    van der Spuy, Wendy J., Pretorius, Etheresia · 2009 · Nutrition Research Reviews
  54. Behavioral effects of SQSTM1/p62 overexpression in mice: Support for a mitochondrial role in depression and anxiety
    Seibenhener, M. Lamar, Zhao, Ting, Du, Yifeng, Calderilla-Barbosa, Luis, Yan, Jin, Jiang, Jianxiong, Wooten, Marie W., Wooten, Michael C. · 2013 · Behavioural Brain Research
  55. Diaminodiphenyl sulfone–induced parkin ameliorates age-dependent dopaminergic neuronal loss
    Lee, Yun-Il, Kang, Hojin, Ha, Young Wan, Chang, Ki-Young, Cho, Sung-Chun, Song, Sang Ok, Kim, Hyein, Jo, Areum, Khang, Rin, Choi, Jeong-Yun et al. · 2016 · Neurobiology of Aging
  56. Thyroid Hormone Transport into Cellular Tissue
    Holtorf, Kent · 2014 · Journal of Restorative Medicine
  57. Young Astrocytic Mitochondria Attenuate the Elevated Level of CCL11 in the Aged Mice, Contributing to Cognitive Function Improvement
    Tashiro, Ryosuke, Ozaki, Dan, Bautista-Garrido, Jesus, Sun, Guanghua, Obertas, Lidiya, Mobley, Alexis S., Kim, Gab Seok, Aronowski, Jaroslaw, Jung, Joo Eun · 2023 · International Journal of Molecular Sciences
  58. A transgenic model to study the pathogenesis of somatic mtDNA mutation accumulation in β‐cells
    Bensch, K. G., DeGraaf, W., Hansen, P. A., Zassenhaus, H. P., Corbett, J. A. · 2007 · Diabetes Obesity and Metabolism
  59. Multifunctional nanocomposites utilizing ruthenium (II) complex/manganese (IV) dioxide nanoparticle for synergistic reinforcing radioimmunotherapy
    Peng, Jian, Quan, Dong-Ling, Yang, Guang, Wei, Lin-Tao, Yang, Zhuan, Dong, Zhi-Ying, Zou, Yi-Ming, Hou, Ying-Ke, Chen, Jin-Xiang, Lv, Lin et al. · 2024 · Journal of Nanobiotechnology