Neuronal Polarity

Microtubule assembly, organization and dynamics in axons and dendrites

Conde, C., & Cáceres, A. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2631 · Cited by 1,086

Role of tau protein in both physiological and pathological conditions

AVILA, J., LUCAS, J. J., PÉREZ, M., & HERNÁNDEZ, F. (2004) · Physiological Reviews · doi:10.1152/physrev.00024.2003 · Cited by 1,005

Branching out: mechanisms of dendritic arborization

Jan, Y.-N., & Jan, L. Y. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2836 · Cited by 693

Actin Cytoskeleton Regulation in Neuronal Morphogenesis and Structural Plasticity

Luo, L. (2002) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.18.031802.150501 · Cited by 658

Neuronal polarity: from extracellular signals to intracellular mechanisms.

Arimura, N., & Kaibuchi, K. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2056 · Cited by 655

Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity

Shi, S.-H., Jan, L. Y., & Jan, Y.-N. (2003) · Cell · doi:10.1016/s0092-8674(02)01249-7 · Cited by 600

Microtubule stabilization specifies initial neuronal polarization

Witte, H., Neukirchen, D., & Bradke, F. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200707042 · Cited by 564

Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice

Dawson, H. N., Ferreira, A., Eyster, M. V., Ghoshal, N., Binder, L. I., & Vitek, M. P. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.6.1179 · Cited by 527

Establishment of axon-dendrite polarity in developing neurons.

Barnes, A. P., & Polleux, F. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125536 · Cited by 523

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

Ashrafi, G., Schlehe, J. S., LaVoie, M. J., & Schwarz, T. L. (2014) · Journal of Cell Biology · doi:10.1083/jcb.201401070 · Cited by 502

The dendritic tree and brain disorders

Kulkarni, V. A., & Firestein, B. L. (2012) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2012.03.005 · Cited by 390

Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway

Niu, S., Renfro, A., Quattrocchi, C. C., Sheldon, M., & D'Arcangelo, G. (2004) · Neuron · doi:10.1016/s0896-6273(03)00819-5 · Cited by 375

A selective filter for cytoplasmic transport at the axon initial segment

Song, A.-H., Wang, D., Chen, G., Li, Y., Luo, J., Duan, S., & Poo, M.-M. (2009) · Cell · doi:10.1016/j.cell.2009.01.016 · Cited by 322

Mixed microtubules steer dynein-driven cargo transport into dendrites

Kapitein, L. C., Schlager, M. A., Kuijpers, M., Wulf, P. S., van Spronsen, M., MacKintosh, F. C., & Hoogenraad, C. C. (2010) · Current Biology · doi:10.1016/j.cub.2009.12.052 · Cited by 320

Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity.

Nishimura, T., Kato, K., Yamaguchi, T., Fukata, Y., Ohno, S., & Kaibuchi, K. (2004) · Nature Cell Biology · doi:10.1038/ncb1118 · Cited by 289

TGF-β Signaling Specifies Axons during Brain Development

Yi, J. J., Barnes, A. P., Hand, R., Polleux, F., & Ehlers, M. D. (2010) · Cell · doi:10.1016/j.cell.2010.06.010 · Cited by 284

WNT signaling in neuronal maturation and synaptogenesis

Rosso, S. B., & Inestrosa, N. C. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00103 · Cited by 272

Cdc42 regulates cofilin during the establishment of neuronal polarity.

Garvalov, B. K., Flynn, K. C., Neukirchen, D., Meyn, L., Teusch, N., Wu, X., Brakebusch, C., Bamburg, J. R., & Bradke, F. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3322-07.2007 · Cited by 262

CRMP-2 Is Involved in Kinesin-1-Dependent Transport of the Sra-1/WAVE1 Complex and Axon Formation

Kawano, Y., Yoshimura, T., Tsuboi, D., Kawabata, S., Kaneko-Kawano, T., Shirataki, H., Takenawa, T., & Kaibuchi, K. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.22.9920-9935.2005 · Cited by 241

Dishevelled promotes axon differentiation by regulating atypical protein kinase C

Zhang, X., Zhu, J., Yang, G.-Y., Wang, Q.-J., Qian, L., Chen, Y.-M., Chen, F., Tao, Y., Hu, H.-S., Wang, T., et al. (2007) · Nature Cell Biology · doi:10.1038/ncb1603 · Cited by 220

The Rac Activator DOCK7 Regulates Neuronal Polarity through Local Phosphorylation of Stathmin/Op18

Watabe-Uchida, M., John, K. A., Janas, J. A., Newey, S. E., & Van Aelst, L. (2006) · Neuron · doi:10.1016/j.neuron.2006.07.020 · Cited by 208

AnkyrinG is required to maintain axo-dendritic polarity in vivo

Sobotzik, J.-M., Sie, J. M., Politi, C., Del Turco, D., Bennett, V., Deller, T., & Schultz, C. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909267106 · Cited by 185

Role of CRMP-2 in neuronal polarity

Arimura, N., Menager, C., Fukata, Y., & Kaibuchi, K. (2004) · Journal of Neurobiology · doi:10.1002/neu.10269 · Cited by 178

Selective Phosphorylation of Adult Tau Isoforms in Mature Hippocampal Neurons Exposed to Fibrillar Aβ

Ferreira, A., Lu, Q., Orecchio, L., & Kosik, K. S. (1997) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1997.0615 · Cited by 178

Control of neuronal polarity and plasticity – a renaissance for microtubules?

Hoogenraad, C. C., & Bradke, F. (2009) · Trends in Cell Biology · doi:10.1016/j.tcb.2009.08.006 · Cited by 173

Uncovering multiple axonal targeting pathways in hippocampal neurons

Wisco, D., Anderson, E. D., Chang, M. C., Norden, C., Boiko, T., Fölsch, H., & Winckler, B. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200307069 · Cited by 163

Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity.

Chen, Y. M., Wang, Q. J., Hu, H. S., Yu, P. C., Zhu, J., Drewes, G., Piwnica-Worms, H., & Luo, Z. G. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509955103 · Cited by 161

Pincher-Mediated Macroendocytosis Underlies Retrograde Signaling by Neurotrophin Receptors

Valdez, G., Akmentin, W., Philippidou, P., Kuruvilla, R., Ginty, D. D., & Halegoua, S. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.5104-04.2005 · Cited by 131

Cytoskeletal microdifferentiation: a mechanism for organizing morphological plasticity in dendrites

Kaech, S., Parmar, H., Roelandse, M., Bornmann, C., & Matus, A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111146798 · Cited by 124

The TC10–Exo70 Complex Is Essential for Membrane Expansion and Axonal Specification in Developing Neurons

Dupraz, S., Grassi, D., Bernis, M. E., Sosa, L., Bisbal, M., Gastaldi, L., Jausoro, I., Cáceres, A., Pfenninger, K. H., & Quiroga, S. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3907-09.2009 · Cited by 111

Identification of Sequence Motifs That Target Neuronal Nicotinic Receptors to Dendrites and Axons

Xu, J., Zhu, Y., & Heinemann, S. F. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0840-06.2006 · Cited by 96

Essential role of the nuclear isoform of RBFOX1, a candidate gene for autism spectrum disorders, in the brain development

Hamada, N., Ito, H., Nishijo, T., Iwamoto, I., Morishita, R., Tabata, H., Momiyama, T., & Nagata, K.-I. (2016) · Scientific Reports · doi:10.1038/srep30805 · Cited by 86

Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity.

Chen, S., Chen, J., Shi, H., Wei, M., Castaneda-Castellanos, D. R., Bultje, R. S., Pei, X., Kriegstein, A. R., Zhang, M., & Shi, S.-H. (2013) · Developmental Cell · doi:10.1016/j.devcel.2012.11.014 · Cited by 82

Hepatocyte growth factor and c-Met promote dendritic maturation during hippocampal neuron differentiation via the Akt pathway

Lim, C. S., & Walikonis, R. S. (2008) · Cellular Signalling · doi:10.1016/j.cellsig.2007.12.013 · Cited by 80

The Role of Mitophagy in Regulating Cell Death

Li, S., Zhang, J., Liu, C., Wang, Q., Yan, J., Hui, L., Jia, Q., Shan, H., Tao, L., & Zhang, M. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/6617256 · Cited by 76

Dendroaxonal transcytosis of transferrin in cultured hippocampal and sympathetic neurons

Hémar, A., Olivo, J.-C., Williamson, E., Saffrich, R., & Dotti, C. G. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-23-09026.1997 · Cited by 61

Mechanisms of trafficking in axons and dendrites: implications for development and neurodegeneration

Sheetz, M. P., Pfister, K. K., Bulinski, J. C., & Cotman, C. W. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00021-5 · Cited by 55

MET Receptor Tyrosine Kinase as an Autism Genetic Risk Factor

Peng, Y., Huentelman, M., Smith, C., & Qiu, S. (2013) · International Review of Neurobiology · doi:10.1016/b978-0-12-418700-9.00005-8 · Cited by 49

Faulty splicing and cytoskeleton abnormalities in Huntington's disease

Fernández‐Nogales, M., Santos‐Galindo, M., Hernández, I. H., Cabrera, J. R., & Lucas, J. J. (2016) · Brain Pathology · doi:10.1111/bpa.12430 · Cited by 41

The cytoplasmic localization of ADNP through 14-3-3 promotes sex-dependent neuronal morphogenesis, cortical connectivity, and calcium signaling

Bennison, S. A., Blazejewski, S. M., Liu, X., Hacohen-Kleiman, G., Sragovich, S., Zoidou, S., Touloumi, O., Grigoriadis, N., Gozes, I., & Toyo-oka, K. (2023) · Molecular Psychiatry · doi:10.1038/s41380-022-01939-3 · Cited by 42

Bisphenol-A impairs synaptic formation and function by RGS4-mediated regulation of BDNF signaling in the cerebral cortex

Hyun, S.-A., Ko, M. Y., Jang, S., Lee, B.-S., Rho, J., Kim, K. K., Kim, W.-Y., & Ka, M. (2022) · Disease Models & Mechanisms · doi:10.1242/dmm.049177 · Cited by 40

Rufy3, a protein specifically expressed in neurons, interacts with actin‐bundling protein Fascin to control the growth of axons

Wei, Z., Sun, M., Liu, X., Zhang, J., & Jin, Y. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12740 · Cited by 39

ERK2-mediated phosphorylation of Par3 regulates neuronal polarization.

Funahashi, Y., Namba, T., Fujisue, S., Itoh, N., Nakamuta, S., Kato, K., Shimada, A., Xu, C., Shan, W., Nishioka, T., et al. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.4210-12.2013 · Cited by 38