I NHIBITION OF C ARCINOGENESIS BY D IETARY P OLYPHENOLIC C OMPOUNDS

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

Jang, M., Cai, L., Udeani, G. O., Slowing, K. V., Thomas, C. F., Beecher, C. W. W., Fong, H. H. S., Farnsworth, N. R., Kinghorn, A. D., Mehta, R. G., et al. (1997) · Science · doi:10.1126/science.275.5297.218 · Cited by 4,935

Dietary Intake and Bioavailability of Polyphenols

Scalbert, A., & Williamson, G. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.8.2073s · Cited by 3,658

Antioxidant and Prooxidant Behavior of Flavonoids: Structure-Activity Relationships

Cao, G., Sofic, E., & Prior, R. L. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00351-6 · Cited by 2,415

Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers

Guido, S., Joy, D. C., Joseph, T., Majeed, M. A., Rajendran, R., & Srinivas, P. (1998) · Planta Medica · doi:10.1055/s-2006-957450 · Cited by 1,976

Soy intake and cancer risk: A review of the in vitro and in vivo data

Messina, M. J., Persky, V., Setchell, K. D. R., & Barnes, S. (1994) · Nutrition and Cancer · doi:10.1080/01635589409514310 · Cited by 1,315

Phyto-oestrogens and Western Diseases

Adlercreutz, H., & Mazur, W. (1997) · Annals of Medicine · doi:10.3109/07853899709113696 · Cited by 1,282

Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands

Hertog, M. G. L., Hollman, P. C. H., Katan, M. B., & Kromhout, D. (1993) · Nutrition and Cancer · doi:10.1080/01635589309514267 · Cited by 1,216

Tea and Cancer

Yang, C. S., & Wang, Z.-Y. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.13.1038 · Cited by 995

Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers

Hollman, P. C. H., de Vries, J., van Leeuwen, S., Mengelers, M. J. B., & Katan, M. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.6.1276 · Cited by 956

Phenol Antioxidant Quantity and Quality in Foods: Vegetables

Vinson, J. A., Hao, Y., Su, X., & Zubik, L. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf980295o · Cited by 948

Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters by tea and curcumin

Li, N., Chen, X. L., Liao, J., Yang, G., Wang, S., Josephson, Y., Han, C., Chen, J., Huang, M., & Yang, C. S. (2002) · Carcinogenesis · doi:10.1093/carcin/23.8.1307 · Cited by 217

Dietary Intake of Natural Antioxidants: Vitamins and Polyphenols

Landete, J. M. (2013) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2011.555018 · Cited by 229

Metabolic engineering of flavonoids in tomato (Solanum lycopersicum): the potential for metabolomics

Bovy, A. G., Schijlen, E. G. W. M., & Hall, R. D. (2007) · Metabolomics · doi:10.1007/s11306-007-0074-2 · Cited by 216

Epigenetic Alterations in the Gastrointestinal Tract: Current and Emerging Use for Biomarkers of Cancer

Grady, W. M., Yu, M., & Markowitz, S. D. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.09.058 · Cited by 219

Therapeutic potential and health benefits ofSargassumspecies

Yende, S. R., Chaugule, B. B., & Harle, U. N. (2014) · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review · doi:10.4103/0973-7847.125514 · Cited by 206

Epigenetics and its role in male infertility

Dada, R., Kumar, M., Jesudasan, R. A., Fernández, J. L., Gosálvez, J., & Agarwal, A. K. (2012) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-012-9715-0 · Cited by 217

Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo.

Naasani, I., Oh-hashi, F., Oh‐hara, T., Feng, W. Y., Johnston, J. S., Chan, K., & Tsuruo, T. (2003) · PubMed · Cited by 205

Absorption of kaempferol from endive, a source of kaempferol-3-glucuronide, in humans

DuPont, M. S., Day, A. J., Bennett, R. N., Mellon, F. A., & Kroon, P. A. (2004) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601916 · Cited by 206

Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis

Gossé, F., Guyot, S., Roussi, S., Lobstein, A., Fischer, B. E., Seiler, N., & Raul, F. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi074 · Cited by 205

Combinatorial Epigenetics Impact of Polyphenols and Phytochemicals in Cancer Prevention and Therapy

Arora, I., Sharma, M., & Tollefsbol, T. O. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20184567 · Cited by 206

Flavokawain A, a Novel Chalcone from Kava Extract, Induces Apoptosis in Bladder Cancer Cells by Involvement of Bax Protein-Dependent and Mitochondria-Dependent Apoptotic Pathway and Suppresses Tumor Growth in Mice

Zi, X., & Simoneau, A. R. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3803 · Cited by 202

Plant Flavone Apigenin: an Emerging Anticancer Agent

Shankar, E., Goel, A., Gupta, K., & Gupta, S. (2017) · Current Pharmacology Reports · doi:10.1007/s40495-017-0113-2 · Cited by 202

Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells

Li, Y., Yuan, Y.-Y., Meeran, S. M., & Tollefsbol, T. O. (2010) · Molecular Cancer · doi:10.1186/1476-4598-9-274 · Cited by 199

Hop Compounds: Extraction Techniques, Chemical Analyses, Antioxidative, Antimicrobial, and Anticarcinogenic Effects

Hrnčič, M. K., Španinger, E., Košir, I. J., Knez, Ž., & Bren, U. (2019) · Nutrients · doi:10.3390/nu11020257 · Cited by 205

Anthocyanin fraction from potato extracts is cytotoxic to prostate cancer cells through activation of caspase-dependent and caspase-independent pathways

Reddivari, L., Vanamala, J., Chintharlapalli, S. R., Safe, S. H., & Miller, J. C. (2007) · Carcinogenesis · doi:10.1093/carcin/bgm117 · Cited by 197

Dietary Polyphenols in Prevention and Treatment of Prostate Cancer

Lall, R. K., Syed, D. N., Adhami, V. M., Khan, M. I., & Mukhtar, H. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16023350 · Cited by 195

Phenolics as Antioxidants

Grace, S. C. (2005) · Wiley eBooks · doi:10.1002/9780470988565.ch6 · Cited by 192

Interaction of kaempferol with human serum albumin: A fluorescence and circular dichroism study

Matei, I., & Hillebrand, M. (2009) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2009.09.037 · Cited by 192

Dietary flavonols and flavonol‐rich foods intake and the risk of breast cancer

Adebamowo, C., Cho, E., Sampson, L., Katan, M., Spiegelman, D. L., Willett, W. C., & Holmes, M. D. (2004) · International Journal of Cancer · doi:10.1002/ijc.20741 · Cited by 191

Mechanisms of Inhibition of Tumor Angiogenesis and Vascular Tumor Growth by Epigallocatechin-3-Gallate

Fassina, G., Venè, R., Morini, M., Minghelli, S., Benelli, R., Noonan, D. M., & Albini, A. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-03-0672 · Cited by 188

Food Phenolic Compounds: Main Classes, Sources and Their Antioxidant Power

Giada, M. D. L. R. (2013) · InTech eBooks · doi:10.5772/51687 · Cited by 193

Anthocyanin-Rich Extract From Aronia meloncarpa E. Induces a Cell Cycle Block in Colon Cancer but Not Normal Colonic Cells

Malik, M., Zhao, C., Schoene, N. W., Guisti, M. M., Moyer, M. P., & Magnuson, B. A. (2003) · Nutrition and Cancer · doi:10.1207/s15327914nc4602_12 · Cited by 184

The Interaction between Epigenetics, Nutrition and the Development of Cancer

Bishop, K. S., & Ferguson, L. R. (2015) · Nutrients · doi:10.3390/nu7020922 · Cited by 188

Potential Therapeutic Targets of Quercetin, a Plant Flavonol, and Its Role in the Therapy of Various Types of Cancer through the Modulation of Various Cell Signaling Pathways

Almatroodi, S. A., Alsahli, M. A., Almatroudi, A., Verma, A. K., Aloliqi, A. A., Allemailem, K. S., Khan, A. A., & Rahmani, A. H. (2021) · Molecules · doi:10.3390/molecules26051315 · Cited by 194

Characterization of the Oxidase Activity in Mammalian Catalase

Vetrano, A. M., Heck, D. E., Mariano, T. M., Mishin, V. M., Laskin, D. L., & Laskin, J. D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503991200 · Cited by 183

Protective role of quercetin against lead-induced inflammatory response in rat kidney through the ROS-mediated MAPKs and NF-κB pathway

Liu, C., Sun, Y.-Z., Sun, J.-M., Ma, J., & Cheng, C. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2012.06.011 · Cited by 183

Of the Major Phenolic Acids Formed during Human Microbial Fermentation of Tea, Citrus, and Soy Flavonoid Supplements, Only 3,4-Dihydroxyphenylacetic Acid Has Antiproliferative Activity ,

Gao, K., Xu, A., Krul, C. A. M., Venema, K., Liu, Y., Niu, Y., Lu, J., Bensoussan, L., Seeram, N. P., Heber, D., et al. (2006) · Journal of Nutrition · doi:10.1093/jn/136.1.52 · Cited by 183

Curcumin inhibits hepatitis C virus replication via suppressing the Akt‐SREBP‐1 pathway

Kim, K., Kim, K. H., Kim, H. Y., Cho, H. K., Sakamoto, N., & Cheong, J. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.12.019 · Cited by 182

Diet and cancer prevention

McCullough, M. L., & Giovannucci, E. L. (2004) · Oncogene · doi:10.1038/sj.onc.1207716 · Cited by 185

Chrysin inhibits expression of hypoxia-inducible factor-1α through reducing hypoxia-inducible factor-1α stability and inhibiting its protein synthesis

Fu, B., Xue, J., Li, Z., Shi, X., Jiang, B., & Fang, J. S. (2007) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0526 · Cited by 183

Overview of polyphenols and their properties

Belščak‐Cvitanović, A., Durgo, K., Huđek, A., Bačun‐Družina, V., & Komes, D. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813572-3.00001-4 · Cited by 204

Cancer Prevention with Promising Natural Products: Mechanisms of Action and Molecular Targets

Pratheeshkumar, P., Sreekala, C., Zhang, Z., Budhraja, A., Ding, S., Son, Y., Wang, X., Hitron, J. A., Hyun-Jung, K., Wang, L., et al. (2012) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152012803833035 · Cited by 180

Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells

Xavier, C. P. R., Lima, C. F., Preto, A., Seruca, R., Fernandes‐Ferreira, M., & Pereira‐Wilson, C. (2009) · Cancer Letters · doi:10.1016/j.canlet.2009.02.041 · Cited by 175

Potential health enhancing properties of edible flowers from Thailand

Kaisoon, O., Konczak, I., & Siriamornpun, S. (2011) · Food Research International · doi:10.1016/j.foodres.2011.06.016 · Cited by 176

Phenolic profiles of Andean purple corn (Zea mays L.)

Pedreschi, R., & Cisneros‐Zevallos, L. (2005) · Food Chemistry · doi:10.1016/j.foodchem.2005.11.004 · Cited by 176

Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells

Chen, Z. (2004) · Carcinogenesis · doi:10.1093/carcin/bgh183 · Cited by 175

Proposed Criteria for Assessing the Efficacy of Cancer Reduction by Plant Foods Enriched in Carotenoids, Glucosinolates, Polyphenols and Selenocompounds

Finley, J. W. (2005) · Annals of Botany · doi:10.1093/aob/mci123 · Cited by 176

The Potential Role of Apigenin in Cancer Prevention and Treatment

Rahmani, A. H., Alsahli, M. A., Almatroudi, A., Almogbel, M. A., Khan, A. A., Anwar, S., & Almatroodi, S. A. (2022) · Molecules · doi:10.3390/molecules27186051 · Cited by 189

Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling

Scarlatti, F., Sala, G., Somenzi, G., Signorelli, P., Sacchi, N., & Ghidoni, R. (2003) · The FASEB Journal · doi:10.1096/fj.03-0292fje · Cited by 174

Rye phenolics in nutrition and health

Bondia‐Pons, I., Aura, A., Vuorela, S., Kolehmainen, M., Mykkänen, H. M., & Poutanen, K. S. (2009) · Journal of Cereal Science · doi:10.1016/j.jcs.2009.01.007 · Cited by 173

The antioxidant effect of tannic acid on the in vitro copper-mediated formation of free radicals

Andrade, R. G., Dalvi, L. T., Silva, J. M. C., Lopes, G. K. B., Alonso, A., & Hermes‐Lima, M. (2005) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2005.02.016 · Cited by 173

Antioxidant Profiling of Native Andean Potato Tubers (Solanum tuberosum L.) Reveals Cultivars with High Levels of β-Carotene, α-Tocopherol, Chlorogenic Acid, and Petanin

André, C. M., Oufir, M., Guignard, C., Hoffmann, L., Hausman, J.-F., Evers, D., & Larondelle, Y. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0726583 · Cited by 170

SIRT1 stimulation by polyphenols is affected by their stability and metabolism

de Boer, V. C. J., de Goffau, M. C., Arts, I. C. W., Hollman, P. C. H., & Keijer, J. (2006) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2006.02.007 · Cited by 168

Chemopreventive actions of polyphenolic compounds in cancer

Soobrattee, M. A., Bahorun, T., & Aruoma, O. I. (2006) · BioFactors · doi:10.1002/biof.5520270103 · Cited by 168

APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions

Thakur, S., Sarkar, B., Cholia, R. P., Gautam, N., Dhiman, M., & Mantha, A. K. (2014) · Experimental & Molecular Medicine · doi:10.1038/emm.2014.42 · Cited by 167

Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis

Hsu, Y., Kuo, P., Tzeng, W. S., & Lin, C. (2005) · Food and Chemical Toxicology · doi:10.1016/j.fct.2005.10.003 · Cited by 167

Brewers' spent grain; bioactivity of phenolic component, its role in animal nutrition and potential for incorporation in functional foods: a review

McCarthy, A. L., O’Callaghan, Y. C., Piggott, C. O., Fitzgerald, R. J., & O’Brien, N. M. (2012) · Proceedings of The Nutrition Society · doi:10.1017/s0029665112002820 · Cited by 167

The Hormetic Role of Dietary Antioxidants in Free Radical-Related Diseases

Calabrese, V., Cornelius, C., Salinaro, A. T., Cambria, M. T., Locascio, M., Rienzo, L., Condorelli, D. F., Mancuso, C., LORENZO, A. D., & Calabrese, E. J. (2010) · Current Pharmaceutical Design · doi:10.2174/138161210790883615 · Cited by 167

Antiangiogenic mechanisms of diet-derived polyphenols

Cao, Y., Cao, R., & Bråkenhielm, E. (2002) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(02)00204-8 · Cited by 166

Antioxidant flavonoids bind human serum albumin

Kanakis, C. D., Tarantilis, P. Α., Polissiou, M. G., Diamantoglou, S., & Tajmir‐Riahi, H. A. (2006) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2006.03.051 · Cited by 166

Green tea polyphenol (−)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells

Annabi, B., Lachambre, M., Bousquet-Gagnon, N., Pagé, M., Gingras, D., & Béliveau, R. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(01)00187-2 · Cited by 165

[6]-Gingerol Induces Cell Cycle Arrest and Cell Death of Mutant p53-expressing Pancreatic Cancer Cells

Park, Y. J., Wen, J., Bang, S., Park, S. W., & Song, S. Y. (2006) · Yonsei Medical Journal · doi:10.3349/ymj.2006.47.5.688 · Cited by 164

Events associated with apoptotic effect of p-Coumaric acid in HCT-15 colon cancer cells

Jaganathan, S. K. (2013) · World Journal of Gastroenterology · doi:10.3748/wjg.v19.i43.7726 · Cited by 163

Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer

Yang, C., Gundala, S. R., Mukkavilli, R., Vangala, S., Reid, M., & Aneja, R. (2015) · Carcinogenesis · doi:10.1093/carcin/bgv046 · Cited by 173

Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients

Brand, W., Schutte, M. E., Williamson, G., van Zanden, J. J., Cnubben, N. H. P., Groten, J. P., van BLADEREN, P. J., & Rietjens, I. M. C. M. (2006) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2006.07.081 · Cited by 161

Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel Inhibit growth of human lung cancer cells by apoptosis

Xiao, H., Yang, C. S., Li, S., Jin, H., Ho, C., & Patel, T. (2008) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200800057 · Cited by 161

Dietary Lignans: Potential Role in Cancer Prevention

Webb, A., & McCullough, M. L. (2005) · Nutrition and Cancer · doi:10.1207/s15327914nc5102_1 · Cited by 163

Antioxidant Activity of Some Jordanian Medicinal Plants Used Traditionally for Treatment of Diabetes

Al-Mustafa, A. H., & Al-Thuniba, O. Y. (2008) · Pakistan Journal of Biological Sciences · doi:10.3923/pjbs.2008.351.358 · Cited by 160

Association between Pterostilbene and Quercetin Inhibits Metastatic Activity of B16 Melanoma

Ferrer, P., Asensi, M. A., Segarra, R., Ortega, Á., Benlloch, M., Obrador, E., Varea, T., Asensio, G., Jordá, L., & Estrela, J. M. (2005) · Neoplasia · doi:10.1593/neo.04337 · Cited by 159

Dietary flavonoid intake and lung cancer—A population‐based case‐control study

Cui, Y., Morgenstern, H., Greenland, S., Tashkin, D. P., Mao, J. T., Cai, L., Cozen, W., Mack, T. M., Lu, Q., & Zhang, Z. (2008) · Cancer · doi:10.1002/cncr.23398 · Cited by 158

Development of novel cationic chitosan- and anionic alginate–coated poly(D,L-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol

Sechi, M., Vanna, S., Roggio, A. M., Siliani, Piccinini, M., Marceddu, S., & Mariani, A. (2012) · International Journal of Nanomedicine · doi:10.2147/ijn.s36684 · Cited by 158

Resveratrol is a potent inducer of apoptosis in human melanoma cells

Niles, R. M., McFarland, M., Weimer, M. B., Redkar, A., Fu, Y.-M., & Meadows, G. G. (2003) · Cancer Letters · doi:10.1016/s0304-3835(02)00676-6 · Cited by 156

Protective activity of tomato products on in vivo markers of lipid oxidation

Visioli, F., Riso, P., Grande, S., Galli, C., & Porrini, M. (2003) · European Journal of Nutrition · doi:10.1007/s00394-003-0415-5 · Cited by 155

Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells.

Jiang, H., Shang, X., Wu, H., Gautam, S. C., Al‐Holou, S. N., Li, C., Kuo, J., Zhang, L., & Chopp, M. (2009) · PubMed · Cited by 154

Antioxidant and Antiproliferative Activities of Loach (Misgurnus anguillicaudatus) Peptides Prepared by Papain Digestion

You, L., Zhao, M., Liu, R. H., & Regenstein, J. M. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf2016368 · Cited by 153

A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines

Li, Y., Gan, G., Zhang, H., Wu, H., Li, C., Huang, Y., Yan-wen, L., & Liu, J. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2007.05.016 · Cited by 151

Anticancer Properties of Flavonoids: Roles in Various Stages of Carcinogenesis

Clere, N., Faure, S., Martínez, M. C., & Andriantsitohaina, R. (2011) · Cardiovascular & Hematological Agents in Medicinal Chemistry · doi:10.2174/187152511796196498 · Cited by 153

The citrus flavonoid naringenin stimulates DNA repair in prostate cancer cells

Gao, K., Henning, S. M., Niu, Y., Youssefian, A. A., Seeram, N. P., Xu, A., & Heber, D. (2005) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2005.05.009 · Cited by 150

Nutraceuticals, apoptosis, and disease prevention

Gosslau, A., & Chen, K. Y. (2003) · Nutrition · doi:10.1016/j.nut.2003.09.017 · Cited by 149

Essential oil components of orange peels and antimicrobial activity

Geraci, A., Stefano, V. A. D., Martino, E. D., Schillaci, D., & Schicchi, R. (2016) · Natural Product Research · doi:10.1080/14786419.2016.1219860 · Cited by 150

Benefits of whole ginger extract in prostate cancer

Karna, P., Chagani, S., Gundala, S. R., Rida, P. C. G., Asif, G., Sharma, V., Gupta, M. V., & Aneja, R. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511003308 · Cited by 150

Apoptotic effect of 3,4‐dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation

Lin, H., Chen, J., Huang, C., & Wang, C. (2007) · International Journal of Cancer · doi:10.1002/ijc.22571 · Cited by 147

A combination of indole-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy

Nakamura, Y., Yogosawa, S., Izutani, Y., Watanabe, H., Otsuji, E., & Sakai, T. (2009) · Molecular Cancer · doi:10.1186/1476-4598-8-100 · Cited by 146

Structural and Functional Characterization of Polyphenols Isolated from Acerola ( Malpighia emarginata DC.) Fruit

Hanamura, T., Hagiwara, T., & Kawagishi, H. (2005) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.69.280 · Cited by 145

Phenolic Content and Antioxidant Properties of Soybean (Glycine max (L.) Merr.) Seeds

Malenčić, Đ., Popović, M., & Miladinović, J. (2007) · Molecules · doi:10.3390/12030576 · Cited by 144

Tomato and Soy Polyphenols Reduce Insulin-Like Growth Factor-I–Stimulated Rat Prostate Cancer Cell Proliferation and Apoptotic Resistance In Vitro via Inhibition of Intracellular Signaling Pathways Involving Tyrosine Kinase

Wang, S., DeGroff, V. L., & Clinton, S. K. (2003) · Journal of Nutrition · doi:10.1093/jn/133.7.2367 · Cited by 143

Metabolism of Flavonoids via Enteric Recycling: Mechanistic Studies of Disposition of Apigenin in the Caco-2 Cell Culture Model

Hu, M., Chen, J., & Lin, H. (2003) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.053496 · Cited by 140

Purification, characterisation and stability of an antioxidant peptide derived from sandfish ( Arctoscopus japonicus ) protein hydrolysates

Jang, H. L., Liceaga, A. M., & Yoon, K. Y. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.11.020 · Cited by 139

Quercetin promotes degradation of survivin and thereby enhances death-receptor–mediated apoptosis in glioma cells

Siegelin, M. D., Reuß, D., Habel, A., Rami, A., & von Deimling, A. (2008) · Neuro-Oncology · doi:10.1215/15228517-2008-085 · Cited by 138

Phytochemical screening and antimicrobial activity of root and stem extracts of wild Eurycoma longifolia Jack (Tongkat Ali)

Khanam, Z., Wen, C. S., & Bhat, I. U. H. (2014) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2014.04.006 · Cited by 136

Polyphenols, autophagy and doxorubicin-induced cardiotoxicity

Shabalala, S. C., Muller, C. J. F., Louw, J., & Johnson, R. (2017) · Life Sciences · doi:10.1016/j.lfs.2017.05.003 · Cited by 140

Punica granatum (Pomegranate) activity in health promotion and cancer prevention

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Beetroot ( Beta vulgaris L.) Extract Ameliorates Gentamicin-Induced Nephrotoxicity Associated Oxidative Stress, Inflammation, and Apoptosis in Rodent Model

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