Encoding of reward and space during a working memory task in the orbitofrontal cortex and anterior cingulate sulcus
Open accessAbstract
Several lines of research indicate that emotional and motivational information may be useful in guiding the allocation of attentional resources. Two areas of the frontal lobe that are particularly implicated in the encoding of motivational information are the orbital prefrontal cortex (PFo) and the dorsomedial region of prefrontal cortex, specifically the anterior cingulate sulcus (PFcs). However, it remains unclear whether these areas use this information to influence spatial attention. We used single-unit neurophysiology to examine whether, at the level of individual neurons, there was evidence for integration between reward information and spatial attention. We trained two subjects to perform a task that required them to attend to a spatial location across a delay under different expectancies of reward for correct performance. We balanced the order of presentation of spatial and reward information so we could assess the neuronal encoding of the two pieces of information independently and conjointly. We found little evidence for encoding of the spatial location in either PFo or PFcs. In contrast, both areas encoded the expected reward. Furthermore, PFo consistently encoded reward more quickly than PFcs, although reward encoding was subsequently more prevalent and stronger in PFcs. These results suggest a differential contribution of PFo and PFcs to reward encoding, with PFo potentially more important for initially determining the value of rewards predicted by sensory stimuli. They also suggest that neither PFo nor PFcs play a direct role in the control of spatial attention.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Recent studies in nonhuman primates identified the orbitofrontal cortex as a region that processes reward but not working memory-related information.
“Recent studies in nonhuman primates 1) identified the orbitofrontal cortex as a region that processes reward but not working memory-related information [70]”
From Linking ADHD to the Neural Circuitry of Attention (2017) · cites this paper as [70]
Cites
An Integrative Theory of Prefrontal Cortex Function
Miller, E. K., & Cohen, J. D. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.167 · Cited by 12,803 · see citing works
Cognitive and emotional influences in anterior cingulate cortex
Bush, G., Luu, P., & Posner, M. I. (2000) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01483-2 · Cited by 6,259 · see citing works
Insensitivity to future consequences following damage to human prefrontal cortex
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994) · Cognition · doi:10.1016/0010-0277(94)90018-3 · Cited by 6,128 · see citing works
Predictive reward signal of dopamine neurons
Schultz, W. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.1.1 · Cited by 4,564 · see citing works
Anterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance
Carter, C. S., Braver, T. S., Barch, D. M., Botvinick, M. M., Noll, D., & Cohen, J. D. (1998) · Science · doi:10.1126/science.280.5364.747 · Cited by 3,273 · see citing works
The role of the medial frontal cortex in cognitive control
Ridderinkhof, K. R., Ullsperger, M., Crone, E. A., & Nieuwenhuis, S. (2004) · Science · doi:10.1126/science.1100301 · Cited by 2,974 · see citing works
Anterior Cingulate Conflict Monitoring and Adjustments in Control
Kerns, J. G., Cohen, J. D., MacDonald, A. W., Cho, R. Y., Stenger, V. A., & Carter, C. S. (2004) · Science · doi:10.1126/science.1089910 · Cited by 2,891 · see citing works
A neural system for error detection and compensation
Gehring, W. J., Goss, B., Coles, M. G. H., Meyer, D. E., & Donchin, E. (1993) · Psychological Science · doi:10.1111/j.1467-9280.1993.tb00586.x · Cited by 2,862 · see citing works
Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex
Funahashi, S., Bruce, C. J., & Goldman-Rakic, P. S. (1989) · Journal of Neurophysiology · doi:10.1152/jn.1989.61.2.331 · Cited by 2,685 · see citing works
Ongur, D. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.206 · Cited by 2,627 · see citing works
Attentional bias in emotional disorders.
MacLeod, C., Mathews, A., & Tata, P. R. (1986) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.95.1.15 · Cited by 2,553 · see citing works
Common regions of the human frontal lobe recruited by diverse cognitive demands
Duncan, J., & Owen, A. M. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01633-7 · Cited by 2,498 · see citing works
Neurons in the orbitofrontal cortex encode economic value
Padoa-Schioppa, C., & Assad, J. A. (2006) · Nature · doi:10.1038/nature04676 · Cited by 1,598 · see citing works
Miltner, W. H. R., Braun, C. H., & Coles, M. G. H. (1997) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1997.9.6.788 · Cited by 1,530 · see citing works
Two types of dopamine neuron distinctly convey positive and negative motivational signals
Matsumoto, M., & Hikosaka, O. (2009) · Nature · doi:10.1038/nature08028 · Cited by 1,378 · see citing works
Relative reward preference in primate orbitofrontal cortex
Tremblay, L., & Schultz, W. (1999) · Nature · doi:10.1038/19525 · Cited by 1,314 · see citing works
Midbrain dopamine neurons encode a quantitative reward prediction error signal
Bayer, H. M., & Glimcher, P. W. (2005) · Neuron · doi:10.1016/j.neuron.2005.05.020 · Cited by 1,304 · see citing works
Overlapping mechanisms of attention and spatial working memory
Awh, E., & Jonides, J. (2001) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01593-x · Cited by 1,229 · see citing works
Eling, P. (1993) · Acta Psychologica · doi:10.1016/0001-6918(93)90027-o · Cited by 1,198 · see citing works
Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys
Carmichael, S. T., & Price, J. L. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903630408 · Cited by 1,197 · see citing works
Dynamic Shifts of Limited Working Memory Resources in Human Vision
Bays, P. M., & Husain, M. (2008) · Science · doi:10.1126/science.1158023 · Cited by 1,111 · see citing works
Mesulam, M.-M. (1999) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1999.0482 · Cited by 1,096 · see citing works
Action sets and decisions in the medial frontal cortex
RUSHWORTH, M., WALTON, M., KENNERLEY, S., & BANNERMAN, D. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.07.009 · Cited by 1,004 · see citing works
Self-citationOptimal decision making and the anterior cingulate cortex
Kennerley, S. W., Walton, M. E., Behrens, T. E. J., Buckley, M. J., & Rushworth, M. F. S. (2006) · Nature Neuroscience · doi:10.1038/nn1724 · Cited by 948 · see citing works
Self-citationOrbitofrontal cortex and its contribution to decision-making.
Wallis, J. D. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.30.051606.094334 · Cited by 938 · see citing works
Self-citationThe Anatomical Connections of the Macaque Monkey Orbitofrontal Cortex. A Review
Cavada, C. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.220 · Cited by 917 · see citing works
Integration of What and Where in the Primate Prefrontal Cortex
Rao, S. C., Rainer, G., & Miller, E. K. (1997) · Science · doi:10.1126/science.276.5313.821 · Cited by 877 · see citing works
An adaptive coding model of neural function in prefrontal cortex
Duncan, J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35097575 · Cited by 874 · see citing works
Sensory and premotor connections of the orbital and medial prefrontal cortex of macaque monkeys
Carmichael, S. T., & Price, J. L. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903630409 · Cited by 678 · see citing works
Wallis, J. D., & Miller, E. K. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02922.x · Cited by 628 · see citing works
Self-citationCingulate cortex of the rhesus monkey: I. Cytoarchitecture and thalamic afferents
Vogt, B. A., Pandya, D. N., & Rosene, D. L. (1987) · Journal of Comparative Neurology · doi:10.1002/cne.902620207 · Cited by 604 · see citing works
Roesch, M. R., Calu, D. J., & Schoenbaum, G. (2007) · Nature Neuroscience · doi:10.1038/nn2013 · Cited by 597 · see citing works
Motivation and cognitive control in the human prefrontal cortex
Kouneiher, F., Charron, S., & Koechlin, E. (2009) · Nature Neuroscience · doi:10.1038/nn.2321 · Cited by 590 · see citing works
Izquierdo, A., Suda, R. K., & Murray, E. A. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1921-04.2004 · Cited by 588 · see citing works
Selective representation of relevant information by neurons in the primate prefrontal cortex
Rainer, G., Asaad, W. F., & Miller, E. K. (1998) · Nature · doi:10.1038/31235 · Cited by 585 · see citing works
Baxter, M. G., Parker, A., Lindner, C. C. C., Izquierdo, A. D., & Murray, E. A. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-11-04311.2000 · Cited by 582 · see citing works
Funahashi, S., Bruce, C. J., & Goldman-Rakic, P. S. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-04-01479.1993 · Cited by 581 · see citing works
Neuronal Activity Related to Reward Value and Motivation in Primate Frontal Cortex
Roesch, M. R., & Olson, C. R. (2004) · Science · doi:10.1126/science.1093223 · Cited by 535 · see citing works
Anterior Cingulate: Single Neuronal Signals Related to Degree of Reward Expectancy
Shidara, M., & Richmond, B. J. (2002) · Science · doi:10.1126/science.1069504 · Cited by 515 · see citing works
LaBar, K. S., Gitelman, D. R., Parrish, T. B., & Mesulam, M. M. (1999) · NeuroImage · doi:10.1006/nimg.1999.0503 · Cited by 514 · see citing works
Midbrain dopamine neurons encode decisions for future action
Morris, G., Nevet, A., Arkadir, D., Vaadia, E., & Bergman, H. (2006) · Nature Neuroscience · doi:10.1038/nn1743 · Cited by 503 · see citing works
Dorsal anterior cingulate cortex shows fMRI response to internal and external error signals
Holroyd, C. B., Nieuwenhuis, S., Yeung, N., Nystrom, L. E., Mars, R. B., COLES, M. G. H., & Cohen, J. D. (2004) · Nature Neuroscience · doi:10.1038/nn1238 · Cited by 487 · see citing works
Ullsperger, M., & von Cramon, D. Y. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-10-04308.2003 · Cited by 484 · see citing works
Critchley, H., & Rolls, E. T. (1996) · Journal of Neurophysiology · doi:10.1152/jn.1996.75.4.1673 · Cited by 467 · see citing works
Covert Visual Spatial Orienting and Saccades: Overlapping Neural Systems
Nobre, A. C., Gitelman, D. R., Dias, E. C., & Mesulam, M. M. (2000) · NeuroImage · doi:10.1006/nimg.2000.0539 · Cited by 465 · see citing works
Paus, T., Koski, L. M., Caramanos, Z., & Westbury, C. F. (1998) · Neuroreport · doi:10.1097/00001756-199806220-00001 · Cited by 462 · see citing works
Mogg, K., Bradley, B. P., Field, M., & De Houwer, J. (2003) · Addiction · doi:10.1046/j.1360-0443.2003.00392.x · Cited by 455 · see citing works
Neurons in the frontal lobe encode the value of multiple decision variables
Kennerley, S. W., Dahmubed, A. F., Lara, A. H., & Wallis, J. D. (2009) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21100 · Cited by 453 · see citing works
Self-citationBachevalier, J., & Mishkin, M. (1986) · Behavioural Brain Research · doi:10.1016/0166-4328(86)90225-1 · Cited by 446 · see citing works
Medial prefrontal cell activity signaling prediction errors of action values
Matsumoto, M., Matsumoto, K., Abe, H., & Tanaka, K. (2007) · Nature Neuroscience · doi:10.1038/nn1890 · Cited by 440 · see citing works
Prefrontal connections of medial motor areas in the rhesus monkey
Bates, J. F., & Goldman, P. S. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903360205 · Cited by 432 · see citing works
Modulation of spatial attention by fear-conditioned stimuli: an event-related fMRI study
Armony, J. L. (2002) · Neuropsychologia · doi:10.1016/s0028-3932(01)00178-6 · Cited by 411 · see citing works
Croxson, P. L., Johansen-Berg, H., Behrens, T. E. J., Robson, M. D., Pinsk, M. A., Gross, C. G., Richter, W., Richter, M. C., Kastner, S., & Rushworth, M. F. S. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1311-05.2005 · Cited by 410 · see citing works
Neuronal correlates of goal-based motor selection in the prefrontal cortex.
Matsumoto, K., Suzuki, W., & Tanaka, K. (2003) · Science · doi:10.1126/science.1084204 · Cited by 384 · see citing works
Visual Selective Attention and the Effects of Monetary Rewards
Libera, C. D., & Chelazzi, L. (2006) · Psychological Science · doi:10.1111/j.1467-9280.2006.01689.x · Cited by 365 · see citing works
Functional organization of the medial frontal cortex
Rushworth, M. F., Buckley, M. J., Behrens, T. E., Walton, M. E., & Bannerman, D. M. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.03.001 · Cited by 353 · see citing works
Reward Encoding in the Monkey Anterior Cingulate Cortex
Amiez, C., Joseph, J., & Procyk, E. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhj046 · Cited by 351 · see citing works
Frontal cortex subregions play distinct roles in choices between actions and stimuli
Rudebeck, P. H., Behrens, T. E., Kennerley, S. W., Baxter, M. G., Buckley, M. J., Walton, M. E., & Rushworth, M. F. S. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.3541-08.2008 · Cited by 350 · see citing works
Self-citationMeunier, M. (1997) · Neuropsychologia · doi:10.1016/s0028-3932(97)00027-4 · Cited by 348 · see citing works
Arana, F. S., Parkinson, J. A., Hinton, E. C., Holland, A. J., Owen, A. M., & Roberts, A. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-29-09632.2003 · Cited by 342 · see citing works
Behavioral Shifts and Action Valuation in the Anterior Cingulate Cortex
Quilodran, R., Rothé, M., & Procyk, E. (2008) · Neuron · doi:10.1016/j.neuron.2007.11.031 · Cited by 335 · see citing works
Human anterior cingulate neurons and the integration of monetary reward with motor responses
Williams, Z. M., Bush, G., Rauch, S. L., Cosgrove, G. R., & Eskandar, E. N. (2004) · Nature Neuroscience · doi:10.1038/nn1354 · Cited by 332 · see citing works
Seo, H., & Lee, D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2369-07.2007 · Cited by 324 · see citing works
Mogg, K., Bradley, B. P., Hyare, H., & Lee, S. (1998) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(97)00062-4 · Cited by 308 · see citing works
Anterior cingulate activity during routine and non-routine sequential behaviors in macaques
Procyk, E., Tanaka, Y. L., & Joseph, J. (2000) · Nature Neuroscience · doi:10.1038/74880 · Cited by 290 · see citing works
Reward-Related Neuronal Activity During Go-Nogo Task Performance in Primate Orbitofrontal Cortex
Tremblay, L., & Schultz, W. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.4.1864 · Cited by 287 · see citing works
Williams, S. M., & Goldman-Rakic, P. S. (1993) · Cerebral Cortex · doi:10.1093/cercor/3.3.199 · Cited by 284 · see citing works
Attentional Biases for Emotional Faces
Bradley, B. P., Mogg, K., Millar, N., Bonham-Carter, C., Fergusson, E. C., Jenkins, J. J., & Parr, M. (1997) · Cognition & Emotion · doi:10.1080/026999397380014 · Cited by 282 · see citing works
Connections of the Monkey Cingulate Cortex
Hoesen, G. W. V., Morecraft, R. J., & Vogt, B. A. (1993) · Birkhäuser Boston eBooks · doi:10.1007/978-1-4899-6704-6_9 · Cited by 276 · see citing works
Convergence of Limbic Input to the Cingulate Motor Cortex in the Rhesus Monkey
Morecraft, R. J., & Hoesen, G. W. V. (1998) · Brain Research Bulletin · doi:10.1016/s0361-9230(97)00344-4 · Cited by 276 · see citing works
Representation of Attended Versus Remembered Locations in Prefrontal Cortex
Lebedev, M., Messinger, A., Kralik, J. D., & Wise, S. P. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020365 · Cited by 275 · see citing works
Sustained activity in the medial wall during working memory delays
Petit, L., Courtney, S. M., Ungerleider, L. G., & Haxby, J. V. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-22-09429.1998 · Cited by 274 · see citing works
Attentional bias to threat in clinical anxiety states
Mogg, K., Mathews, A., & Eysenck, M. W. (1992) · Cognition & Emotion · doi:10.1080/02699939208411064 · Cited by 256 · see citing works
Kondo, H., Saleem, K. S., & Price, J. L. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20796 · Cited by 236 · see citing works
Fictive Reward Signals in the Anterior Cingulate Cortex
Hayden, B. Y., Pearson, J. M., & Platt, M. L. (2009) · Science · doi:10.1126/science.1168488 · Cited by 235 · see citing works
The sensory nature of mnemonic representation in the primate prefrontal cortex
Constantinidis, C., Franowicz, M. N., & Goldman-Rakic, P. S. (2001) · Nature Neuroscience · doi:10.1038/85179 · Cited by 233 · see citing works
Filtering of neural signals by focused attention in the monkey prefrontal cortex
Everling, S., Tinsley, C. J., Gaffan, D., & Duncan, J. (2002) · Nature Neuroscience · doi:10.1038/nn874 · Cited by 224 · see citing works
Architecture and neurocytology of monkey cingulate gyrus
Vogt, B. A., Vogt, L., Farber, N. B., & Bush, G. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20512 · Cited by 223 · see citing works
Motivation sharpens exogenous spatial attention.
Engelmann, J. B., & Pessoa, L. (2007) · Emotion · doi:10.1037/1528-3542.7.3.668 · Cited by 221 · see citing works
Mohanty, A., Gitelman, D. R., Small, D. M., & Mesulam, M. M. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn021 · Cited by 221 · see citing works
Kennerley, S. W., & Wallis, J. D. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06743.x · Cited by 204 · see citing works
Self-citationThe Anterior Cingulate and Reward-Guided Selection of Actions
Hadland, K. A., Rushworth, M. F. S., Gaffan, D., & Passingham, R. E. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00634.2002 · Cited by 201 · see citing works
The role of the orbitofrontal cortex in the pursuit of happiness and more specific rewards
Burke, K. A., Franz, T. M., Miller, D. N., & Schoenbaum, G. M. (2008) · Nature · doi:10.1038/nature06993 · Cited by 181 · see citing works
Heterogeneity of cingulate contributions to spatial attention
Mesulam, M. M., Nobre, A. C., Kim, Y.-H., Parrish, T. B., & Gitelman, D. R. (2001) · NeuroImage · doi:10.1006/nimg.2001.0768 · Cited by 179 · see citing works
The Role of Working Memory Representations in the Control of Attention
Woodman, G. F., Luck, S. J., & Schall, J. D. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm065 · Cited by 177 · see citing works
Dum, R. P., & Strick, P. L. (1993) · Birkhäuser Boston eBooks · doi:10.1007/978-1-4899-6704-6_15 · Cited by 165 · see citing works
Emotion?attention network interactions during a visual oddball task
Fichtenholtz, H. M., Dean, H. L., Dillon, D. G., Yamasaki, H., McCarthy, G., & LaBar, K. S. (2004) · Cognitive Brain Research · doi:10.1016/j.cogbrainres.2004.01.006 · Cited by 161 · see citing works
Neuronal Activity in Macaque SEF and ACC During Performance of Tasks Involving Conflict
Nakamura, K., Roesch, M. R., & Olson, C. R. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00305.2004 · Cited by 160 · see citing works
Neuronal Activity in Primate Orbitofrontal Cortex Reflects the Value of Time
Roesch, M. R., & Olson, C. R. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00373.2005 · Cited by 155 · see citing works
Effects of lesions of the medial forebrain on alternation behavior of rhesus monkeys
Pribram, K. H., Wilson, W. A., & Connors, J. (1962) · Experimental Neurology · doi:10.1016/0014-4886(62)90013-4 · Cited by 147 · see citing works
The effect of cingulate cortex lesions on task switching and working memory
Rushworth, M. F. S., Hadland, K. A., Gaffan, D., & Passingham, R. E. (2003) · Journal of Cognitive Neuroscience · doi:10.1162/089892903321593072 · Cited by 138 · see citing works
Behavioral and Neural Changes after Gains and Losses of Conditioned Reinforcers
Seo, H., & Lee, D. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4726-08.2009 · Cited by 137 · see citing works
Expectations, gains, and losses in the anterior cingulate cortex
Sallet, J., Quilodran, R., Rothé, M., Vezoli, J., Joseph, J., & Procyk, E. (2007) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/cabn.7.4.327 · Cited by 136 · see citing works
Reward-Dependent Modulation of Working Memory in Lateral Prefrontal Cortex
Kennerley, S. W., & Wallis, J. D. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5353-08.2009 · Cited by 132 · see citing works
Self-citationCingulate unit activity and delayed response
Niki, H., & Watanabe, M. (1976) · Brain Research · doi:10.1016/0006-8993(76)90412-1 · Cited by 120 · see citing works
Enhanced Processing of Threat Stimuli under Limited Attentional Resources
Martino, B. D., Kalisch, R., Rees, G. E., & Dolan, R. J. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn062 · Cited by 89 · see citing works
Neuronal Activity Related to Anticipated Reward in Frontal Cortex
Roesch, M. R., & Olson, C. R. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1401.004 · Cited by 86 · see citing works
Dynamic Encoding of Responses and Outcomes by Neurons in Medial Prefrontal Cortex
Luk, C.-H., & Wallis, J. D. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0386-09.2009 · Cited by 81 · see citing works
Self-citationCharacterization of serial order encoding in the monkey anterior cingulate sulcus
Procyk, E., & Joseph, J. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01738.x · Cited by 54 · see citing works
Anxiety and the Processing of Threatening Information
Mathews, A. (1988) · Springer eBooks · doi:10.1007/978-94-009-2792-6_11 · Cited by 38 · see citing works
Ichihara‐Takeda, S., & Funahashi, S. (2007) · Experimental Brain Research · doi:10.1007/s00221-007-0941-0 · Cited by 37 · see citing works
An, X., Bandler, R., �ng�r, D., & Price, J. L. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19981130)401:4
Flagged first, then by citations
Cited by
Sorted by citations
Neurobiology of economic choice: a good-based model
Padoa-Schioppa, C. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113648 · Cited by 600 · see citing works
Dorsal Anterior Cingulate Cortex: A Bottom-Up View
Heilbronner, S. R., & Hayden, B. Y. (2016) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070815-013952 · Cited by 469 · see citing works
Double dissociation of value computations in orbitofrontal and anterior cingulate neurons
Kennerley, S. W., Behrens, T. E. J., & Wallis, J. D. (2011) · Nature Neuroscience · doi:10.1038/nn.2961 · Cited by 452 · see citing works
Self-citationRudebeck, P. H., & Murray, E. A. (2014) · Neuron · doi:10.1016/j.neuron.2014.10.049 · Cited by 405 · see citing works
Cross-species studies of orbitofrontal cortex and value-based decision-making
Wallis, J. D. (2011) · Nature Neuroscience · doi:10.1038/nn.2956 · Cited by 356 · see citing works
Self-citationOrbitofrontal Cortex: A Neural Circuit for Economic Decisions
Padoa‐Schioppa, C., & Conen, K. E. (2017) · Neuron · doi:10.1016/j.neuron.2017.09.031 · Cited by 296 · see citing works
Taste, olfactory, and food reward value processing in the brain
Rolls, E. T. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.03.002 · Cited by 287 · see citing works
Neurons in anterior cingulate cortex multiplex information about reward and action
Hayden, B. Y., & Platt, M. L. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4874-09.2010 · Cited by 236 · see citing works
Sustained Activity Encoding Working Memories: Not Fully Distributed
Leavitt, M. L., Mendoza-Halliday, D., & Martínez-Trujillo, J. (2017) · Trends in Neurosciences · doi:10.1016/j.tins.2017.04.004 · Cited by 232 · see citing works
Chase, H. W., Kumar, P., Eickhoff, S. B., & Dombrovski, A. Y. (2015) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-015-0338-7 · Cited by 225 · see citing works
Haber, S. N., & Behrens, T. E. J. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.031 · Cited by 230 · see citing works
Neuronal Encoding of Subjective Value in Dorsal and Ventral Anterior Cingulate Cortex
Cai, X., & Padoa‐Schioppa, C. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.3864-11.2012 · Cited by 205 · see citing works
Ubiquity and Specificity of Reinforcement Signals throughout the Human Brain
Vickery, T. J., Chun, M. M., & Lee, D. (2011) · Neuron · doi:10.1016/j.neuron.2011.08.011 · Cited by 185 · see citing works
Heterogeneous reward signals in prefrontal cortex
Wallis, J. D., & Kennerley, S. W. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.02.009 · Cited by 186 · see citing works
Self-citationKennerley, S. W., & Walton, M. E. (2011) · Behavioral Neuroscience · doi:10.1037/a0023575 · Cited by 179 · see citing works
Self-citationRudebeck, P. H., Saunders, R. C., Lundgren, D. A., & Murray, E. A. (2017) · Neuron · doi:10.1016/j.neuron.2017.07.042 · Cited by 170 · see citing works
Linking ADHD to the Neural Circuitry of Attention
Mueller, A., Hong, D. S., Shepard, S., & Moore, T. (2017) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2017.03.009 · Cited by 158 · see citing works
What Can Medical Education Learn From the Neurobiology of Learning?
Friedlander, M. J., Andrews, L., Armstrong, E. G., Aschenbrenner, C. A., Kass, J. S., Ogden, P. E., Schwartzstein, R. M., & Viggiano, T. R. (2011) · Academic Medicine · doi:10.1097/acm.0b013e31820dc197 · Cited by 160 · see citing works
Padoa‐Schioppa, C., & Cai, X. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06262.x · Cited by 157 · see citing works
Hillman, K. L., & Bilkey, D. K. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1273-10.2010 · Cited by 148 · see citing works
Reconciling persistent and dynamic hypotheses of working memory coding in prefrontal cortex
Cavanagh, S. E., Towers, J. P., Wallis, J. D., Hunt, L. T., & Kennerley, S. W. (2018) · Nature Communications · doi:10.1038/s41467-018-05873-3 · Cited by 162 · see citing works
Self-citationSocial error monitoring in macaque frontal cortex
Yoshida, K., Saito, N., Iriki, A., & Isoda, M. (2012) · Nature Neuroscience · doi:10.1038/nn.3180 · Cited by 150 · see citing works
Orbitofrontal Circuits Control Multiple Reinforcement-Learning Processes
Groman, S. M., Keistler, C., Keip, A. J., Hammarlund, E., Dileone, R., Pittenger, C., Lee, D., & Taylor, J. R. (2019) · Neuron · doi:10.1016/j.neuron.2019.05.042 · Cited by 142 · see citing works
Transient Inactivation of Orbitofrontal Cortex Blocks Reinforcer Devaluation in Macaques
West, E. A., DesJardin, J. T., Gale, K., & Málková, L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3295-11.2011 · Cited by 137 · see citing works
Neural Basis of Motivational and Cognitive Control
Mars, R., Sallet, J., Mfs., R., & Yeung, N. (2011) · The MIT Press eBooks · doi:10.7551/mitpress/9780262016438.001.0001 · Cited by 128 · see citing works
Kaping, D., Vinck, M. A., Hutchison, R. M., Everling, S., & Womelsdorf, T. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001224 · Cited by 120 · see citing works
Economic Choice as an Untangling of Options into Actions
Yoo, S. B. M., & Hayden, B. Y. (2018) · Neuron · doi:10.1016/j.neuron.2018.06.038 · Cited by 104 · see citing works
Models, movements, and minds: bridging the gap between decision making and action
Wispinski, N. J., Gallivan, J. P., & Chapman, C. S. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13973 · Cited by 105 · see citing works
Dissociating contributions of ACC and vmPFC in reward prediction, outcome, and choice
Vassena, E., Krebs, R. M., Silvetti, M., Fias, W., & Verguts, T. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.04.019 · Cited by 106 · see citing works
Orbitofrontal Cortical Neurons Encode Expectation-Driven Initiation of Reward-Seeking
Moorman, D. E., & Aston‐Jones, G. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3216-13.2014 · Cited by 99 · see citing works
Choice Coding in Frontal Cortex during Stimulus-Guided or Action-Guided Decision-Making
Luk, C.-H., & Wallis, J. D. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.4920-12.2013 · Cited by 96 · see citing works
Self-citationArulpragasam, A. R., Cooper, J. A., Nuutinen, M. R., & Treadway, M. T. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800444115 · Cited by 92 · see citing works
Individualized real-time fMRI neurofeedback to attenuate craving in nicotine-dependent smokers
Hartwell, K. J., Hanlon, C. A., Li, X., Borckardt, J. J., Canterberry, M., Prisciandaro, J. J., Maria, M. M. M., LeMatty, T., George, M. S., & Brady, K. T. (2015) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.140200 · Cited by 94 · see citing works
Vernon, A. C., Crum, W. R., Lerch, J. P., Chege, W., Natesan, S., Modo, M., Cooper, J. D., Williams, S., & Kapur, S. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.09.012 · Cited by 83 · see citing works
Marsh, B. T., Tarigoppula, V. S. A., Chen, C., & Francis, J. T. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.1802-14.2015 · Cited by 77 · see citing works
Reward Stability Determines the Contribution of Orbitofrontal Cortex to Adaptive Behavior
Riceberg, J. S., & Shapiro, M. L. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0776-12.2012 · Cited by 68 · see citing works
Comparison of Strategy Signals in the Dorsolateral and Orbital Prefrontal Cortex
Tsujimoto, S., Genovesio, A., & Wise, S. P. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.5816-10.2011 · Cited by 69 · see citing works
Bardi, L., Desmet, C., Nijhof, A. D., Wiersema, J. R., & Braß, M. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw143 · Cited by 68 · see citing works
Back to basics: Making predictions in the orbitofrontal–amygdala circuit
Sharpe, M. J., & Schoenbaum, G. M. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.04.009 · Cited by 61 · see citing works
Cingulate-Hippocampus Coherence and Trajectory Coding in a Sequential Choice Task
Remondes, M., & Wilson, M. A. (2013) · Neuron · doi:10.1016/j.neuron.2013.08.037 · Cited by 59 · see citing works
Covert shift of attention modulates the value encoding in the orbitofrontal cortex
Xie, Y., Nie, C., & Yang, T. (2018) · eLife · doi:10.7554/elife.31507 · Cited by 58 · see citing works
Event-based control of autonomic and emotional states by the anterior cingulate cortex
Seamans, J. K., & Floresco, S. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.12.026 · Cited by 58 · see citing works
Representations of appetitive and aversive information in the primate orbitofrontal cortex
Morrison, S. E., & Salzman, C. D. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06255.x · Cited by 57 · see citing works
Modulation of working memory function by motivation through loss‐aversion
Krawczyk, D. C., & D’Esposito, M. (2011) · Human Brain Mapping · doi:10.1002/hbm.21472 · Cited by 57 · see citing works
Stable and dynamic representations of value in the prefrontal cortex
Enel, P., Wallis, J. D., & Rich, E. L. (2020) · eLife · doi:10.7554/elife.54313 · Cited by 50 · see citing works
Self-citationWhite and Gray Matter Abnormalities in Narcolepsy with Cataplexy
Scherfler, C., Frauscher, B., Schocke, M. F. H., Nocker, M., Gschliesser, V., Ehrmann, L., Niederreiter, M., Esterhammer, R., Seppi, K., Brandauer, E., et al. (2012) · SLEEP · doi:10.5665/sleep.1692 · Cited by 53 · see citing works
Riceberg, J. S., & Shapiro, M. L. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.2951-16.2016 · Cited by 52 · see citing works
Guillem, K., & Ahmed, S. H. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw398 · Cited by 46 · see citing works
Anterior cingulate cortex encoding of effortful behavior
Porter, B. S., Hillman, K. L., & Bilkey, D. K. (2019) · Journal of Neurophysiology · doi:10.1152/jn.00654.2018 · Cited by 45 · see citing works
Remondes, M., & Wilson, M. A. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.10.005 · Cited by 49 · see citing works
Sucrose intensity coding and decision-making in rat gustatory cortices
Fonseca, E., de Lafuente, V., Simon, S. A., & Gutiérrez, R. (2018) · eLife · doi:10.7554/elife.41152 · Cited by 46 · see citing works
Attention as foraging for information and value
Manohar, S., & Husain, M. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00711 · Cited by 45 · see citing works
Reinforcement learning detuned in addiction: integrative and translational approaches
Groman, S. M., Thompson, S. L., Lee, D., & Taylor, J. R. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.11.007 · Cited by 39 · see citing works
Connecting Circuits with Networks in Addiction Neuroscience: A Salience Network Perspective
Cushnie, A. K., Tang, W., & Heilbronner, S. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24109083 · Cited by 43 · see citing works
Increased Firing to Cues That Predict Low-Value Reward in the Medial Orbitofrontal Cortex
Burton, A. C., Kashtelyan, V., Bryden, D. W., & Roesch, M. R. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht189 · Cited by 42 · see citing works
Reward Acts on the pFC to Enhance Distractor Resistance of Working Memory Representations
Fallon, S. J., & Cools, R. (2014) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00676 · Cited by 38 · see citing works
Ventral Striatum Encodes Past and Predicted Value Independent of Motor Contingencies
Goldstein, B. L., Barnett, B. R., Vásquez, G. V. M., Tobia, S. C., Kashtelyan, V., Burton, A. C., Bryden, D. W., & Roesch, M. R. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5349-11.2012 · Cited by 39 · see citing works
Challenges of Interpreting Frontal Neurons during Value-Based Decision-Making
Wallis, J. D., & Rich, E. L. (2011) · Frontiers in Neuroscience · doi:10.3389/fnins.2011.00124 · Cited by 40 · see citing works
Self-citationKuusinen, V., Cesnaite, E., Peräkylä, J., Ogawa, K. H., & Hartikainen, K. M. (2018) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2018.00437 · Cited by 37 · see citing works
The drive to strive: goal generation based on current needs
Murray, E. A., & Rudebeck, P. H. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00112 · Cited by 37 · see citing works
Valence processing in the PFC: Reconciling circuit-level and systems-level views
Coley, A. A., Padilla-Coreano, N., Patel, R. R., & Tye, K. M. (2021) · International review of neurobiology · doi:10.1016/bs.irn.2020.12.002 · Cited by 35 · see citing works
Absence of Spatial Tuning in the Orbitofrontal Cortex
Grattan, L. E., & Glimcher, P. W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112750 · Cited by 34 · see citing works
Robust Encoding of Spatial Information in Orbitofrontal Cortex and Striatum
Yoo, S. B. M., Sleezer, B. J., & Hayden, B. Y. (2018) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01259 · Cited by 32 · see citing works
Fujimoto, A., Murray, E. A., & Rudebeck, P. H. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2014781118 · Cited by 33 · see citing works
Anterior Cingulate Cortex Ablation Disrupts Affective Vigor and Vigilance
Bliss‐Moreau, E., Santistevan, A. C., Bennett, J., Moadab, G., & Amaral, D. G. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0673-21.2021 · Cited by 32 · see citing works
Prefrontal expectancy and reinforcement-driven antidepressant placebo effects
Peciña, M., Heffernan, J., Wilson, J., Zubieta, J., & Dombrovski, A. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0263-y · Cited by 28 · see citing works
Neural correlates of audio‐visual object recognition: Effects of implicit spatial congruency
Plank, T., Rosengarth, K., Song, W., Ellermeier, W., & Greenlee, M. W. (2011) · Human Brain Mapping · doi:10.1002/hbm.21254 · Cited by 28 · see citing works
Reinforcement Learning during Adolescence in Rats
Afshar, N. M., Keip, A. J., Taylor, J. R., Lee, D., & Groman, S. M. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0910-20.2020 · Cited by 23 · see citing works
Chokesuwattanaskul, A., Jiang, H., Bond, R. L., Jiménez, D., Russell, L. L., Sivasathiaseelan, H., Johnson, J. C. S., Benhamou, E., Agustus, J. L., van Leeuwen, J. E. P., et al. (2023) · Brain Communications · doi:10.1093/braincomms/fcad027 · Cited by 24 · see citing works
Hammer, R., Tennekoon, M., Cooke, G. E., Gayda, J., Stein, M. A., & Booth, J. R. (2015) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2015.06.002 · Cited by 21 · see citing works
Ott, T., Stein, A. M., & Nieder, A. (2023) · Nature Communications · doi:10.1038/s41467-023-43271-6 · Cited by 25 · see citing works
Toda, K., Sugase-Miyamoto, Y., Mizuhiki, T., Inaba, K., Richmond, B. J., & Shidara, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030190 · Cited by 21 · see citing works
Kärkkäinen, O. K., Kupila, J., Häkkinen, M. R., Laukkanen, V., Tupala, E., Kautiainen, H., Tiihonen, J., & Storvik, M. (2013) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2013.09.012 · Cited by 19 · see citing works
Guillem, K., & Ahmed, S. H. (2020) · Scientific Reports · doi:10.1038/s41598-020-64962-w · Cited by 17 · see citing works
Functional Interactions of Prefrontal Cortex and the Hippocampus in Learning and Memory
Shapiro, M. L., Riceberg, J. S., Seip-Cammack, K., & Guise, K. G. (2014) · Springer eBooks · doi:10.1007/978-3-7091-1292-2_19 · Cited by 18 · see citing works
Action selection in multi-effector decision making
Madlon‐Kay, S., Pesaran, B., & Daw, N. D. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.12.001 · Cited by 16 · see citing works
Viswanathan, P., & Nieder, A. (2017) · European Journal of Neuroscience · doi:10.1111/ejn.13740 · Cited by 17 · see citing works
González, V. V., Zhang, Y., Ashikyan, S. A., Rickard, A., Yassine, I., Romero-Sosa, J. L., Blaisdell, A. P., & Izquierdo, A. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae135 · Cited by 15 · see citing works
The anterior cingulate cortex and event-based modulation of autonomic states
Seamans, J. K. (2021) · International review of neurobiology · doi:10.1016/bs.irn.2020.11.006 · Cited by 10 · see citing works
Orbitofrontal cortex is selectively activated in a primate model of attentional bias to cocaine cues
Baeg, E., Jedema, H. P., & Bradberry, C. W. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-019-0499-0 · Cited by 10 · see citing works
Wallis, J. D. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-12-804281-6.00015-x · Cited by 7 · see citing works
Self-citationLiu, Y., Zhong, Z., Chen, J., Kuo, H., Chen, X., Wang, P., Shi, M., Yang, M., Liu, B., & Liu, G. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1419128 · Cited by 6 · see citing works
Koloski, M. F., Salimi, M., Hulyalkar, S., Tang, T., Barnes, S. A., Mishra, J., & Ramanathan, D. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.0858-25.2025 · Cited by 6 · see citing works
Aquino, T. G., Courellis, H. S., Mamelak, A. N., Rutishauser, U., & O’Doherty, J. P. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1628-23.2024 · Cited by 6 · see citing works
Sucrose intensity coding and decision-making in rat gustatory corticesPreprint
Fonseca, E., de Lafuente, V., Simon, S. A., & Gutiérrez, R. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/391342 · Cited by 5 · see citing works
“Heart Shots”: a classroom activity to instigate active learning
Abraham, R. R., Vashe, A., & Torke, S. (2015) · AJP Advances in Physiology Education · doi:10.1152/advan.00027.2015 · Cited by 4 · see citing works
Fidelity of the representation of value in decision-making
Bays, P. M., & Dowding, B. A. (2017) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005405 · Cited by 5 · see citing works
Anterior cingulate cortex monitors action state and action content in complex associative learningPreprint
Huang, W., Hall, A. F., Kawalec, N., Opalka, A. N., Liu, J., & Wang, D. V. (2025) · eLife · doi:10.7554/elife.105774 · Cited by 5 · see citing works
Pizzagalli, D. A. (2026) · Nature Mental Health · doi:10.1038/s44220-026-00631-7 · Cited by 3 · see citing works
Miranda, B., Butler, J. L., Malalasekera, W. M. N., Behrens, T. E. J., Dayan, P., & Kennerley, S. W. (2026) · eLife · doi:10.7554/elife.106032.3 · Cited by 2 · see citing works
Self-citationIsoda, M. (2017) · Springer eBooks · doi:10.1007/978-4-431-56508-6_8 · Cited by 2 · see citing works
Aquino, T. G., Courellis, H. S., Mamelak, A. N., Rutishauser, U., & O’Doherty, J. P. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.10.528055 · Cited by 2 · see citing works
The orbitofrontal cortex in adaptive behavior: Prediction, evaluation, and comparison
Murray, E. A., Fellows, L. K., & Rudebeck, P. H. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-820480-1.00088-7 · Cited by 2 · see citing works
Theory Change in Cognitive Neurobiology: The Case of the Orbitofrontal Cortex
Barack, D. L. (2025) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.70003 · Cited by 1 · see citing works
Paholpak, P., & Mendez, M. F. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800105-9.00021-4 · Cited by 1 · see citing works
Miranda, B., Butler, J. L., Malalasekera, W. M. N., Behrens, T. E. J., Dayan, P., & Kennerley, S. W. (2025) · eLife · doi:10.7554/elife.106032.1 · Cited by 1 · see citing works
Self-citationEntropic Decision MakingPreprint
Rebei, A. (2020) · RePEc: Research Papers in Economics · doi:10.48550/arxiv.2001.00122 · Cited by 2 · see citing works
Representational Drift Enables the Temporal Integration of Experiences in ACC Ensemble ActivityPreprint
Wirt, R. A., Ricci, R. M., Soluoku, T. K., Seamans, J. K., & Hyman, J. M. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4568527
- Authors
- Kennerley, S. W., & Wallis, J. D.
- Affiliations
- University of California, Berkeley (US)
- Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, California
- ORCID
- Kennerley, Steven W.
- Venue
- Journal of Neurophysiology
- Publisher
- American Physiological Society
- Published
- 2009-12
- Volume
- 102
- Issue
- 6
- Pages
- 3352-3364
- ISSN
- 0022-3077 (ISSN-L)
- 1522-1598
- PMC
- PMC2804408
- OpenAlex
- W1976273411
- Cited by
- 108
- References
- 102
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 4 · 2023: 5 · 2021: 6 · 2020: 4 · 2019: 5 · 2018: 10 · 2017: 8 · 2016: 5 · 2015: 7 · 2014: 7 · 2013: 8 · 2012: 8
- FWCI
- 4.19
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Neurophysiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- National Institutes of Health (5f32mh081521-02)
- National Institute of Mental Health (F32MH-081521)
- National Institute on Drug Abuse (R01-DA19028, R01DA019028)
- National Institute of Neurological Disorders and Stroke (P01NS040813)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- reward encoding, spatial attention, orbitofrontal cortex, working memory, single-unit recording, reward expectancy, prefrontal cortex, attentional control
- MeSH terms
- Action Potentials, Animals, Attention, Brain Mapping, Gyrus Cinguli, Macaca mulatta, Magnetic Resonance Imaging, Male, Memory, Short-Term, Neurons, Neuropsychological Tests, Regression Analysis, Reward, Space Perception, Time Factors, Prefrontal Cortex
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review