Centella asiatica(L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential

Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function

Howes, M. R., & Houghton, P. J. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(03)00128-x · Cited by 443

Phenolic contents and antioxidant activity of some food and medicinal plants

Bajpai, M., Pande, A., Tewari, S. K., & Prakash, D. (2005) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637480500146606 · Cited by 418

In vitro screening of five local medicinal plants for antibacterial activity using disc diffusion method.

Mr, Z., Rain, A. N., Ar, B., Adlin, A., Norazah, A., & Zakiah, I. (2005) · PubMed · Cited by 357

Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress in rats

Veerendra Kumar, M. H., & Gupta, Y. K. (2002) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(01)00394-4 · Cited by 261

Effect of Centella asiatica on pentylenetetrazole-induced kindling, cognition and oxidative stress in rats

Gupta, Y. K., Kumar, M., & Srivastava, A. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)01044-4 · Cited by 253

Effect of Centella asiatica on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer's disease in rats

Veerendra Kumar, M., & Gupta, Y. (2003) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2003.03842.x · Cited by 249

Screening of Indian medicinal plants for acetylcholinesterase inhibitory activity

Mukherjee, P. K., Venkatesan, K., & Houghton, P. J. (2007) · Phytotherapy Research · doi:10.1002/ptr.2224 · Cited by 228

Effects of Centella asiatica extract on dermal wound healing in rats.

Suguna, L., Sivakumar, P., & Chandrakasan, G. (1996) · PubMed · Cited by 183

Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica

Wattanathorn, J., Mator, L., Muchimapura, S., Tong-un, T., Pasurivong, O., Piyawatkul, N., Yimtae, K., Sripanidkulchai, B., & Singkhoraard, J. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2007.11.038 · Cited by 179

Centella asiatica extract selectively decreases amyloid β levels in hippocampus of Alzheimer's disease animal model

Dhanasekaran, M., Holcomb, L. A., Hitt, A. R., Tharakan, B., Porter, J. W., Young, K. A., & Manyam, B. V. (2009) · Phytotherapy Research · doi:10.1002/ptr.2405 · Cited by 175

Neuroprotective Herbs for the Management of Alzheimer’s Disease

Gregory, J., Vengalasetti, Y. V., Bredesen, D. E., & Rao, R. V. (2021) · Biomolecules · doi:10.3390/biom11040543 · Cited by 264

Chronic Stress and Oxidative Stress as Common Factors of the Pathogenesis of Depression and Alzheimer’s Disease: The Role of Antioxidants in Prevention and Treatment

Juszczyk, G., Mikulska, J., Kasperek, K., Pietrzak, D., Mrozek, W., & Herbet, M. (2021) · Antioxidants · doi:10.3390/antiox10091439 · Cited by 247

Green Synthesis of Metallic Nanoparticles Using Some Selected Medicinal Plants from Southern Africa and Their Biological Applications

Aboyewa, J. A., Sibuyi, N. R. S., Meyer, M., & Oguntibeju, O. O. (2021) · Plants · doi:10.3390/plants10091929 · Cited by 200

Prodrugs of triterpenoids and their derivatives

Zhou, M., Zhang, R., Wang, M., Xu, G., & Liao, S. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.03.005 · Cited by 120

Indian Medicinal Herbs and Formulations for Alzheimer’s Disease, from Traditional Knowledge to Scientific Assessment

Mehla, J., Gupta, P., Pahuja, M., Diwan, D., & Diksha, D. (2020) · Brain Sciences · doi:10.3390/brainsci10120964 · Cited by 108

Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency

Lichota, A., Gwoździński, Ł., & Gwoździński, K. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.04.075 · Cited by 109

In vitro and In vivo Antioxidant, Anti-hyperlipidemic Properties and Chemical Characterization of Centella asiatica (L.) Extract

Kumari, S., Deori, M., Elancheran, R., Kotoky, J., & Devi, R. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00400 · Cited by 105

Centella asiatica (Gotu kola) as a neuroprotectant and its potential role in healthy ageing

Sabaragamuwa, R., Perera, C. O., & Fedrizzi, B. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.07.024 · Cited by 112

High-Altitude Medicinal Plants as Promising Source of Phytochemical Antioxidants to Combat Lifestyle-Associated Oxidative Stress-Induced Disorders

Ashraf, M. V., Khan, S., Misri, S., Gaira, K. S., Rawat, S., Rawat, B., Khan, M. A. H., Shah, A. A., Asgher, M., & Ahmad, S. (2024) · Pharmaceuticals · doi:10.3390/ph17080975 · Cited by 102

Asiaticoside attenuates memory impairment induced by transient cerebral ischemia–reperfusion in mice through anti-inflammatory mechanism

Chen, S., Yin, Z.-J., Jiang, C., Ma, Z., Fu, Q., Qu, R., & Ma, S. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2014.03.004 · Cited by 96

Phytochemicals Bridging Autophagy Induction and Alpha-Synuclein Degradation in Parkinsonism

Limanaqi, F., Biagioni, F., Busceti, C. L., Ryskalin, L., Polzella, M., Frati, A., & Fornai, F. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133274 · Cited by 87

Ethnobotany, phytochemistry, pharmacology, and toxicity of Centella asiatica (L.) Urban: A comprehensive review

Biswas, D., Mandal, S., Chatterjee Saha, S., Tudu, C. K., Nandy, S., Batiha, G. E., Shekhawat, M. S., Pandey, D. K., & Dey, A. (2021) · Phytotherapy Research · doi:10.1002/ptr.7248 · Cited by 83

Centella asiatica attenuates the neurobehavioral, neurochemical and histological changes in transient focal middle cerebral artery occlusion rats

Tabassum, R., Vaibhav, K., Shrivastava, P., Khan, A., Ejaz Ahmed, M., Javed, H., Islam, F., Ahmad, S., Saeed Siddiqui, M., Safhi, M. M., et al. (2013) · Neurological Sciences · doi:10.1007/s10072-012-1163-1 · Cited by 82

Recent Updates in Neuroprotective and Neuroregenerative Potential of Centella asiatica.

Lokanathan, Y., Omar, N., Puzi, N. N. A., Saim, A. B., & Idrus, R. B. H. (2016) · Europe PMC (PubMed Central) · Cited by 82

Mitoprotective Effects of Centella asiatica (L.) Urb.: Anti-Inflammatory and Neuroprotective Opportunities in Neurodegenerative Disease

Wong, J. H., Barron, A. M., & Abdullah, J. M. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.687935 · Cited by 79

Centella asiatica: Secondary metabolites, biological activities and biomass sources

Kunjumon, R., Johnson, A. J., & Baby, S. (2022) · Phytomedicine Plus · doi:10.1016/j.phyplu.2021.100176 · Cited by 79

Biopharmaceutical and pharmacokinetic characterization of asiatic acid in Centella asiatica as determined by a sensitive and robust HPLC–MS method

Yuan, Y., Zhang, H., Feng-feng, S. U. N., Sun, S., Zhu, Z., & Chai, Y. (2015) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2015.01.006 · Cited by 79

Alzheimer Disease: Clues from traditional and complementary medicine

Cooper, E. L., & Ma, M. J. (2017) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2016.12.003 · Cited by 76

Modeling and optimization of microwave-assisted extraction of pentacyclic triterpenes from Centella asiatica leaves using response surface methodology

Yingngam, B., Chiangsom, A., & Brantner, A. H. (2020) · Industrial Crops and Products · doi:10.1016/j.indcrop.2020.112231 · Cited by 75

Asiatic Acid Prevents the Deleterious Effects of Valproic Acid on Cognition and Hippocampal Cell Proliferation and Survival

Welbat, J. U., Sirichoat, A., Chaijaroonkhanarak, W., Prachaney, P., Pannangrong, W., Pakdeechote, P., Sripanidkulchai, B., & Wigmore, P. M. (2016) · Nutrients · doi:10.3390/nu8050303 · Cited by 76

Effects of Asiatic Acid on Spatial Working Memory and Cell Proliferation in the Adult Rat Hippocampus

Sirichoat, A., Chaijaroonkhanarak, W., Prachaney, P., Pannangrong, W., Leksomboon, R., Chaichun, A., Wigmore, P. M., & Welbat, J. U. (2015) · Nutrients · doi:10.3390/nu7105401 · Cited by 69

Mitoprotective effect of Centella asiatica against aluminum-induced neurotoxicity in rats: possible relevance to its anti-oxidant and anti-apoptosis mechanism

Prakash, A. K., & Kumar, A. (2012) · Neurological Sciences · doi:10.1007/s10072-012-1252-1 · Cited by 67

Chitosan-based microneedle arrays for dermal delivery of Centella asiatica

Ryall, C., Chen, S., Duarah, S., & Wen, J. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.122221 · Cited by 65

Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via In Vitro and In Vivo

Hafiz, Z. Z., Amin, M. ‘. M., Johari James, R. M., Teh, L. K., Salleh, M. Z., & Adenan, M. I. (2020) · Molecules · doi:10.3390/molecules25040892 · Cited by 64

Asiatic acid protects against cognitive deficits and reductions in cell proliferation and survival in the rat hippocampus caused by 5-fluorouracil chemotherapy

Chaisawang, P., Sirichoat, A., Chaijaroonkhanarak, W., Pannangrong, W., Sripanidkulchai, B., Wigmore, P. M., & Welbat, J. U. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180650 · Cited by 61

Asiatic acid protects differentiated PC12 cells from Aβ25–35-induced apoptosis and tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β signaling

Cheng, W., Chen, W., Wang, P., & Chu, J. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.07.016 · Cited by 57

Effects of Medhya Rasayana and Yogic practices in improvement of short-term memory among school-going children

Rao, M., & Sarokte, A. (2013) · AYU (An International Quarterly Journal of Research in Ayurveda) · doi:10.4103/0974-8520.127720 · Cited by 56

Recent trends in extraction, identification and quantification methods of Centella asiatica phytochemicals with potential applications in food industry and therapeutic relevance: A review

Tripathy, S., Verma, D. K., Thakur, M., Chakravorty, N., Sıngh, S., & Srivastav, P. P. (2022) · Food Bioscience · doi:10.1016/j.fbio.2022.101864 · Cited by 57

Global Perspective of Plant-Based Cosmetic Industry and Possible Contribution of Sri Lanka to the Development of Herbal Cosmetics

Gamage, D. G. N. D., Dharmadasa, R. M., Abeysinghe, D. C., Wijesekara, R. G. S., Prathapasinghe, G. A., & Someya, T. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/9940548 · Cited by 53

Neuroprotective therapeutics from botanicals and phytochemicals against Huntington's disease and related neurodegenerative disorders

Dey, A., & De, J. N. (2015) · Journal of Herbal Medicine · doi:10.1016/j.hermed.2015.01.002 · Cited by 52

Bioactive Compounds and Bioactivities of Centella asiatica (L.) Urban Prepared by Different Drying Methods and Conditions

Niamnuy, C., Charoenchaitrakool, M., Mayachiew, P., & Devahastin, S. (2013) · Drying Technology · doi:10.1080/07373937.2013.839563 · Cited by 55

Safety and Pharmacokinetics of Standardized Extract of Centella asiatica (ECa 233) Capsules in Healthy Thai Volunteers: A Phase 1 Clinical Study

Songvut, P., Chariyavilaskul, P., Tantisira, M. H., & Khemawoot, P. (2019) · Planta Medica · doi:10.1055/a-0835-6671 · Cited by 50

Advances and emerging research trends for modulation of centelloside biosynthesis in Centella asiatica (L.) Urban- A review

Prasad, A., Mathur, A. K., & Mathur, A. (2019) · Industrial Crops and Products · doi:10.1016/j.indcrop.2019.111768 · Cited by 50

Plants and phytochemicals for treatment of peptic ulcer: An overview

Gupta, M., Kapoor, B., Gupta, R., & Singh, N. (2021) · South African Journal of Botany · doi:10.1016/j.sajb.2020.11.030 · Cited by 49

Ethnobotany, Phytochemistry and Pharmacological Features of Centella asiatica: A Comprehensive Review

Abedi, F., Ramezani, M., Dehghan, R., Amiri, M. S., Moghadam, A. T., Shakour, N., Elyasi, S., Sahebkar, A., & Emami, S. A. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-64872-5_25 · Cited by 49

Protective Effect of Centella asiatica against Aluminium-Induced Neurotoxicity in Cerebral Cortex, Striatum, Hypothalamus and Hippocampus of Rat Brain- Histopathological, and Biochemical Approach

Amjad, S. (2015) · Journal of Molecular Biomarkers & Diagnosis · doi:10.4172/2155-9929.1000212 · Cited by 49

Prospects in the development of natural radioprotective therapeutics with anti-cancer properties from the plants of Uttarakhand region of India

Painuli, S., & Kumar, N. (2016) · Journal of Ayurveda and Integrative Medicine · doi:10.1016/j.jaim.2015.09.001 · Cited by 45

Blood-Brain Barrier Permeability of Asiaticoside, Madecassoside and Asiatic Acid in Porcine Brain Endothelial Cell Model

Hanapi, N. A., Arshad, A. S. M., Abdullah, J. M., Muhammad, T. S. T., & Yusof, S. R. (2020) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2020.09.015 · Cited by 45

Antioxidative role of Traditional Chinese Medicine in Parkinson's disease

Muhammad, F., Liu, Y., Zhou, Y., Yang, H., & Li, H. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114821 · Cited by 47

Comparative studies on Turkish and Indian Centella asiatica (L.) Urban (gotu kola) samples for their enzyme inhibitory and antioxidant effects and phytochemical characterization

Orhan, I. E., Atasu, E., Senol, F. S., Ozturk, N., Demirci, B., Das, K., & Sekeroglu, N. (2013) · Industrial Crops and Products · doi:10.1016/j.indcrop.2013.03.022 · Cited by 44

Protective effect of centella triterpene saponins against cyclophosphamide-induced immune and hepatic system dysfunction in rats: its possible mechanisms of action

Duggina, P., Kalla, C. M., Varikasuvu, S. R., Bukke, S., & Tartte, V. (2015) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-015-0423-y · Cited by 44

Decreasing α-synuclein aggregation by methanolic extract of Centella asiatica in zebrafish Parkinson's model

Khotimah, H., Ali, M., Sumitro, S. B., & Widodo, M. A. (2015) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/j.apjtb.2015.07.024 · Cited by 46

Role of Flavonoids as Wound Healing Agent

Aslam, M. S., Ahmad, M. S., Riaz, H., Raza, S. A., Hussain, S., Qureshi, O. S., Maria, P., Hamzah, Z., & Javed, O. (2018) · InTech eBooks · doi:10.5772/intechopen.79179 · Cited by 40

Neuroprotective Effect for Cerebral Ischemia by Natural Products: A Review

Xie, Q., Li, H., Lu, D., Yuan, J., Ma, R., Li, J., Ren, M., Li, Y., Chen, H., Wang, J., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.607412 · Cited by 43

Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review

Bansal, K., Bhati, H., Vanshita, & Bajpai, M. (2024) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2024.100403 · Cited by 37

Protection of mouse brain from paracetamol-induced stress by Centella asiatica methanol extract

Viswanathan, G., Dan, V. M., Radhakrishnan, N., Nair, A. S., Nair, A. P. R., & Baby, S. (2019) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2019.03.017 · Cited by 37

Nanoemulsions: Summary of a Decade of Research and Recent Advances

Chavda, V. P., Balar, P. C., Bezbaruah, R., Vaghela, D. A., Rynjah, D., Bhattacharjee, B., Sugandhi, V. V., & Paiva‐Santos, A. C. (2024) · Nanomedicine · doi:10.2217/nnm-2023-0199 · Cited by 35

Centella asiatica: Advances in Extraction Technologies, Phytochemistry, and Therapeutic Applications

Hein, Z. M., Gopalakrishna, P. K., Kanuri, A. K., Thomas, W., Hussan, F., Naik, V. R., Shantakumari, N., Che Ramli, M. D., Mohd Moklas, M. A., Che Mohd Nassir, C. M. N., et al. (2025) · Life · doi:10.3390/life15071081 · Cited by 33

Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

Naidoo, D. B., Chuturgoon, A. A., Phulukdaree, A., Guruprasad, K. P., Satyamoorthy, K., & Sewram, V. (2018) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-018-2192-y · Cited by 32

Madecassoside protects BV2 microglial cells from oxygen-glucose deprivation/reperfusion-induced injury via inhibition of the toll-like receptor 4 signaling pathway

Luo, Y., Wang, C., Li, W.-H., Liu, J., He, H.-H., Long, J.-H., Yang, J., Sui, X., Wang, S., You, Z., et al. (2018) · Brain Research · doi:10.1016/j.brainres.2017.11.030 · Cited by 32

Natural Products for Improving Soft Tissue Healing: Mechanisms, Innovations, and Clinical Potential

Alberts, A., Lungescu, I. A., Niculescu, A.-G., & Grumezescu, A. M. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17060758 · Cited by 33

Induction, Multiplication, and Evaluation of Antioxidant Activity of Polyalthia bullata Callus, a Woody Medicinal Plant

Zaman, M. A. K., Azzeme, A. M., Ramle, I. K., Normanshah, N., Ramli, S. N., Shaharuddin, N. A., Ahmad, S., & Abdullah, S. N. A. (2020) · Plants · doi:10.3390/plants9121772 · Cited by 30

Edible freshwater macrophytes: a source of anticancer and antioxidative natural products—a mini-review

Chai, T., Ooh, K.-F., Quah, Y., & Wong, F. (2015) · Phytochemistry Reviews · doi:10.1007/s11101-015-9399-z · Cited by 30

The Multifaceted Role of Neuroprotective Plants in Alzheimer’s Disease Treatment

Zieneldien, T., Kim, J., & Cao, C. (2022) · Geriatrics · doi:10.3390/geriatrics7020024 · Cited by 29

Effects of SuperUlam on Supporting Concentration and Mood: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

Udani, J. K. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/238454 · Cited by 26

Differentiation of Three Centella Species in Australia as Inferred from Morphological Characteristics, ISSR Molecular Fingerprinting and Phytochemical Composition

Alqahtani, A. S., Cho, J., Wong, K. H., Li, K. M., Razmovski‐Naumovski, V., & Li, G. Q. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.01980 · Cited by 26

Hippocampal amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid GluA1 ( AMPA GluA1) receptor subunit involves in learning and memory improvement following treatment withCentella asiaticaextract in adolescent rats

Yeo, N. A. B. M. Y., Muthuraju, S., Wong, J. H., Mohammed, F. R., Senik, M. H., Zhang, J., Yusof, S. R., Jaafar, H., Adenan, M. L., Mohamad, H., et al. (2018) · Brain and Behavior · doi:10.1002/brb3.1093 · Cited by 27

Strategies for Improving Healing of the Gastric Epithelium Using Oral Solid Dispersions Loaded with Pentacyclic Triterpene–Rich Centella Extract

Wannasarit, S., Puttarak, P., Kaewkroek, K., & Wiwattanapatapee, R. (2019) · AAPS PharmSciTech · doi:10.1208/s12249-019-1488-7 · Cited by 26

Can Asiatic Acid from Centella asiatica Be a Potential Remedy in Cancer Therapy?—A Review

Wiciński, M., Fajkiel-Madajczyk, A., Kurant, Z., Gajewska, S., Kurant, D., Kurant, M., & Sousak, M. (2024) · Cancers · doi:10.3390/cancers16071317 · Cited by 29

Role of indigenous herbs in the management of Alzheimer′s disease

Nishteswar, K., Joshi, H., & Karra, R. (2014) · Ancient Science of Life · doi:10.4103/0257-7941.150763 · Cited by 28

Ethnic food culture of Chhattisgarh state of India

Shukla, A. (2021) · Journal of Ethnic Foods · doi:10.1186/s42779-021-00103-6 · Cited by 26

Medhya Rasayanas in Brain Function and Disease

Ray, S. (2015) · Medicinal Chemistry · doi:10.4172/2161-0444.1000309 · Cited by 26

The protective effect of Centella asiatica and its constituent, araliadiol on neuronal cell damage and cognitive impairment

Fujimori, H., Ohba, T., Mikami, M., Nakamura, S., Ito, K., Kojima, H., Takahashi, T., Iddamalgoda, A., Shimazawa, M., & Hara, H. (2021) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2021.11.001 · Cited by 24

Phytochemical and pharmacological evaluation of organic and non-organic cultivated nutritional Centella asiatica collected after different time intervals of harvesting

Bhattacharya, R., Parmar, K. M., Itankar, P. R., & Prasad, S. K. (2017) · South African Journal of Botany · doi:10.1016/j.sajb.2017.06.003 · Cited by 26

Neurotransmitter, Antioxidant and Anti-neuroinflammatory Mechanistic Potentials of Herbal Medicines in Ameliorating Autism Spectrum Disorder

Kardani, A., Soltani, A., Sewell, R. D. E., Shahrani, M., & Rafieian‐Kopaei, M. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666191112143940 · Cited by 23

Morphological Description and Ethnobotanical Review of the Orphan Crop Myin-Hkwa (Centella asiatica L.) From Myanmar

Shukurova, M. K., Myint, D., Yi, S. S., Ohm, M. S., & Watanabe, K. (2021) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2021.680862 · Cited by 23

Biomass and centellosides production in two elite Centella asiatica germplasms from India in response to seasonal variation

Prasad, A., Yadav, K. S., Yadav, N. P., Mathur, A., Sreedhar, R. V., Lal, R. K., & Mathur, A. K. (2016) · Industrial Crops and Products · doi:10.1016/j.indcrop.2016.09.022 · Cited by 23

Protective effects of asiatic acid in a spontaneous type 2 diabetic mouse model

Sun, W. C., Xu, G., Guo, X., Luo, G., Wu, L. J., Hou, Y., Guo, X., Zhou, J., Xu, T., Qin, L., et al. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.6684 · Cited by 23

An Investigation of the Differential Effects of Ursane Triterpenoids fromCentella asiatica, and Their Semisynthetic Analogues, on GABAA Receptors

Hamid, K., Ng, I. O., Tallapragada, V. J., Váradi, L., Hibbs, D. E., Hanrahan, J. R., & Groundwater, P. W. (2016) · Chemical Biology & Drug Design · doi:10.1111/cbdd.12766 · Cited by 23

Behavioral and neurochemical consequences of perinatal exposure to lead in adult male Wistar rats: protective effect by Centella asiatica

Chintapanti, S., Reddy, K. P., & Reddy, P. S. (2018) · Environmental Science and Pollution Research · doi:10.1007/s11356-018-1500-x · Cited by 22

Medicinal herbal remedies in neurodegenerative diseases: an update on antioxidant potential

Sarkar, B., Rana, N., Singh, C., & Singh, A. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03027-5 · Cited by 26

Asiatic acid, an active substance of Centella asiatica, presynaptically depresses glutamate release in the rat hippocampus

Lü, C.-W., Lin, T., Wang, S., & Huang, S.-K. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172781 · Cited by 22

Growth Increase in the Herbaceous Plant Centella asiatica by the Plant Growth-Promoting Rhizobacteria Priestia megaterium HyangYak-01

Jo, H., Lim, K., Ibal, J. C., Kim, M., Kim, H., Baek, C., Heo, Y. M., Lee, H. E., Kang, S., Lee, D., et al. (2023) · Plants · doi:10.3390/plants12132398 · Cited by 20

Study of ameliorating effects of ethanolic extract of Centella asiatica on learning and memory deficit in animal models.

Doknark, S., Mingmalairak, S., Vattanajun, A., Tantisira, B., & Tantisira, M. H. (2014) · PubMed · Cited by 19

Centella asiatica modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

Naidoo, D. B., Chuturgoon, A. A., Phulukdaree, A., Guruprasad, K. P., Satyamoorthy, K., & Sewram, V. (2017) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-017-1865-2 · Cited by 19

A Comparative Study of the Hepatoprotective Effect of Centella asiatica Extract (CA-HE50) on Lipopolysaccharide/d-galactosamine-Induced Acute Liver Injury in C57BL/6 Mice

Hong, W., Hwang‐Bo, J., Jeon, H., Ko, M., Choi, J., Jeong, Y.-J., Park, J.-H., Kim, I., Kim, T., Kim, H., et al. (2021) · Nutrients · doi:10.3390/nu13114090 · Cited by 18

Evaluation of antimicrobial, anticancer potential and Flippase induced leakage in model membrane of Centella asiatica fabricated MgONPs

Khatua, A., Prasad, A., Behuria, H. G., Patel, A. K., Singh, M. K., Madhavan, Y., Saravanan, M., & Meena, R. (2022) · Biomaterials Advances · doi:10.1016/j.bioadv.2022.212855 · Cited by 18

Diabetes mellitus and Alzheimer's disease: Understanding disease mechanisms, their correlation, and promising dual activity of selected herbs

Pramanik, R., Dey, A., Chakrabarty, A. K., Banerjee, D., Narwaria, A., Sharma, S. K., Rai, R. K., Katiyar, C. K., & Dubey, S. K. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118402 · Cited by 18

Antioxidant Activities of Methanol Extracts from Selected Taiwanese Herbaceous Plants

Lin, K., Yeh, H., Lin, S.-Y., Yang, C., Tsai, H.-J., Tsai, J.-J., & Chao, P.-Y. (2014) · Journal of Food and Nutrition Research · doi:10.12691/jfnr-2-8-2 · Cited by 17

Ameliorative Role of Nutraceuticals on Neurodegenerative Diseases Using theDrosophila melanogasteras a Discovery Model to Define Bioefficacy

Himalian, R., Singh, S. K., & Singh, M. P. (2021) · Journal of the American Nutrition Association · doi:10.1080/07315724.2021.1904305 · Cited by 17

Ethno-medicinal plants used for herbal medication of jaundice by the indigenous community of Tripura, India

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Medicinal Plants - Chemical, Biochemical, and Pharmacological Approaches

de Oliveira, M. S., Andrade, E. H. D. A., Kumar, R., & Mali, S. N. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.107682 · Cited by 17

Characterisation of indigenous plants for herbal formulations preparation based on pharmacognostic and physiochemical data

Mochahary, B., Brahma, S., Kalita, M., & Goyal, A. K. (2022) · Plant Science Today · doi:10.14719/pst.1709 · Cited by 16

Centella asiatica and Its Fractions Reduces Lipid Peroxidation Induced by Quinolinic Acid and Sodium Nitroprusside in Rat Brain Regions

Marques, N. F., Stefanello, S. T., Froeder, A. L. F., Busanello, A., Boligon, A. A., Athayde, M. L., Soares, F. A. A., & Fachinetto, R. (2015) · Neurochemical Research · doi:10.1007/s11064-015-1582-5 · Cited by 16

Rice-Based Alcoholic Fermented Beverages of North-East India: Insight into Ethnic Preparation, Microbial Intervention, Ethnobotany, and Health Benefits

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Neuroprotective prospectives of triterpenoids

Bankar, A. A., Nagulwar, V. P., Kotagale, N. R., & Inamdar, N. (2024) · Exploration of neuroscience · doi:10.37349/en.2024.00047 · Cited by 17

Consumption of fresh Centella asiatica improves short term alertness and contentedness in healthy females

Lawal, O. M., Wakel, F., & Dekker, M. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104337 · Cited by 15

The recovery and protective effects of asiatic acid on differentiated human neuroblastoma SH-SY5Y cells cytotoxic-induced by cholesterol

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Synthesis of madecassic acid derivatives and their cytotoxic activity

Lộc, T. V., Như, V. T. Q., Chiến, T. V., Hà, L. T. T., Thảo, T. T. P., & Sung, T. V. (2018) · Zeitschrift für Naturforschung B · doi:10.1515/znb-2017-0172 · Cited by 14

LC-ESI/MS and GC-MS Methanol Extract Analysis, Phytochemical and Antimicrobial Activity Studies of Centella asiatica

Ondeko, D. A., Juma, B. F., Baraza, L. D., & Nyongesa, P. K. (2020) · Asian Journal of Chemical Sciences · doi:10.9734/ajocs/2020/v8i319046 · Cited by 14

Investigation of the in vitro antibacterial, cytotoxic and in vivo analgesic effects of silver nanoparticles coated with Centella asiatica plant extract

Bozkaya, O., Ekici, H., Gök, Z. G., Bozkaya, E., Ekici, S., Yiğitoğlu, M., & Vargel, İ. (2022) · Ankara Üniversitesi Veteriner Fakültesi Dergisi · doi:10.33988/auvfd.1014802 · Cited by 14

Centella asiatica (L.) Urb. attenuates cardiac hypertrophy and improves heart function through multi-level mechanisms revealed by systems pharmacology

Ding, B., Niu, W., Wang, S., Zhang, F., Wang, H., Chen, X., Chen, S., Ma, S., Kang, W., Wang, M., et al. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115106 · Cited by 14

The protective effect of asiatic acid on podocytes in the kidney of diabetic rats.

Chen, Y.-N., Wu, C., Shi, B., Qian, K., & Ding, Y. (2018) · Europe PMC (PubMed Central) · Cited by 14

Exploring aryl hydrocarbon receptor (AhR) as a target for Bisphenol-A (BPA)-induced pancreatic islet toxicity and impaired glucose homeostasis: Protective efficacy of ethanol extract of Centella asiatica

Banerjee, O., Singh, S., Prasad, S. K., Bhattacharjee, A., Seal, T., Mandal, J., Sinha, S., Banerjee, A., Maji, B. K., & Mukherjee, S. (2023) · Toxicology · doi:10.1016/j.tox.2023.153693 · Cited by 13

Centella asiatica Extract Attenuates Kidney Fibrosis Through Reducing Mesenchymal Transition and Inflammation in Ureteral Ligation Model in Mice

Sari, D. C. R., Budiharjo, S., Afifah, H., Jasmin, D., Kokasih, O., Putri, T., Arifiani, K., Setyaningsih, W. A. W., & Arfian, N. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.621894 · Cited by 15

Exploiting Medicinal Plants as Possible Treatments for Acne Vulgaris

Lambrechts, I. A., Canha, M. N. D., & Lall, N. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812475-8.00004-4 · Cited by 13

Screening of different extraction methods for maximum production of total flavonoids, tannins, and antioxidants from Centella asiatica

Hossain, M. A., Ahmad, N., Alam, M., Hossain, M. M., & Sarkar, A. (2024) · Food Research · doi:10.26656/fr.2017.8(1).057 · Cited by 15

Synthesis of asiatic acid derivatives and their cytotoxic activity

Van, L. T., Thi, Q. N. V., Van, C. T., Thi, P. T. T., Thi, N. P., Tuan, T. N., Thi, T. H. L., Thị, N. N., Thi, T. D., & Van, S. T. (2018) · Medicinal Chemistry Research · doi:10.1007/s00044-018-2176-y · Cited by 12

A review of antioxidant and anti-acetylcholinesterase activities of Centella asiatica (L.) Urb. for the treatment of Alzheimer’s disease

Abbas, S., Latif, M. S., Shafie, N. S., Ghazali, M. I., Abidin, N. A. Z., Mustafa, M. K., & Kormin, F. B. (2021) · Food Research · doi:10.26656/fr.2017.5(2).355 · Cited by 13

Analysis of antibacterial, anti-inflammatory, and skin-whitening effect of Centella asiatica (L.) Urban

Goo, Y., Kil, Y. S., Sin, S. M., Lee, D. Y., Jeong, W. M., Ko, K., Yang, K. J., Kim, Y., & Lee, S.-W. (2018) · Journal of Plant Biotechnology · doi:10.5010/jpb.2018.45.2.117 · Cited by 13

doi:10.1155/2012/946259 Review Article Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential

Orhan, I. E. (2016)

Potential neurological applications of Centella asiatica: a brief review

Gofir, A., Wibowo, S., & Hakimi, M. (2021) · Indonesian Journal of Pharmacology and Therapy · doi:10.22146/ijpther.1693 · Cited by 8

Centella asiatica (Gotu kola) as a neuroprotectant and its potential role in healthy ageing

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Gotu Kola (Centella asiatica)

Belwal, T., Andola, H. C., Atanassova, M., Joshi, B., Suyal, R., Thakur, S., Bisht, A., Jantwal, A., BHATT, I. D., & Rawal, R. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812491-8.00038-2 · Cited by 40

Recent Updates in Neuroprotective and Neuroregenerative Potential of Centella asiatica.

Lokanathan, Y., Omar, N., Puzi, N. N. A., Saim, A. B., & Idrus, R. B. H. (2016) · Europe PMC (PubMed Central) · Cited by 82