Neural control of maternal behaviour and olfactory recognition of offspring
Abstract
In terms of reproductive success the quality and duration of maternal care exhibited by any particular species is of paramount importance, and yet compared with the amount of research studying the control of reproductive cycles, sexual behaviour, and fertility, it has historically received considerably less attention. However, we are now beginning to understand how the brain is organised to mediate this complex behaviour and how its expression is orchestrated by different hormonal and neurochemical factors. This review summarises a series of neuroanatomical, electrophysiological, in vivo sampling and behavioural neuropharmacological experiments carried out in sheep. These have attempted to define the neural circuitry and hormonal neurotransmitter systems involved both in the control of maternal behaviour per se and in the selective olfactory recognition of lambs, which is the basis of an exclusive emotional bond between mother and offspring.
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Many sites of action have been implicated for OT in rat social recognition, including the ventral hippocampus, septum, medial preoptic area, and olfactory bulb.
“There have been many sites of action implicated for OT in rat social recognition, including the ventral hippocampus, septum, medial preoptic area, and olfactory bulb [71-74].”
From Oxytocin and the Neural Mechanisms Regulating Social Cognition and Affiliative Behavior (2009) · cites this paper as [73]
Oxytocin, released by the hypothalamic paraventricular nucleus (PVN), is a critical maternal hormone.
“Oxytocin1,2,9–15, which is released by the hypothalamic paraventricular nucleus (PVN), is a critical maternal hormone.”
From Oxytocin neurons enable social transmission of maternal behaviour (2021) · cites this paper as [13]
Oxytocin acts in the brain to increase the salience of social information and enable alloparenting in mice.
“Oxytocin also acts in the brain to increase the salience of social information and enable alloparenting in mice1,9,12–14.”
From Oxytocin neurons enable social transmission of maternal behaviour (2021) · cites this paper as [13]
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“OT promotes maternal care behavior (Pedersen et al., 1982; Fahrbach et al., 1984) and bonding to the offspring (Kendrick et al., 1986, 1997; Keverne and Kendrick, 1992) as well as pair bonding (Carter et al., 1995).”
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- Authors
- Kendrick, K. M., Da Costa, A. P. C., Broad, K. D., Ohkura, S., Guevara, R., Lévy, F., & Keverne, E. B.
- Affiliations
- Babraham Institute (GB)
- University of Cambridge (GB)
- Kyoto University (JP)
- Universidad Nacional Autónoma de México (MX)
- Corresponding author
- Kendrick, Keith M
- Venue
- Brain Research Bulletin
- Publisher
- Elsevier BV
- Published
- 1997
- Volume
- 44
- Issue
- 4
- Pages
- 383-395
- ISSN
- 0361-9230 (ISSN-L)
- OpenAlex
- W2009625337
- Cited by
- 311
- References
- 105
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 6 · 2023: 5 · 2022: 9 · 2021: 9 · 2020: 21 · 2019: 8 · 2018: 5 · 2017: 10 · 2016: 15 · 2015: 16 · 2014: 11 · 2013: 13 · 2012: 16
- FWCI
- 10.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain Research Bulletin (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Human-Animal Interaction Studies
- Keywords
- maternal behavior, olfactory recognition, mother-offspring recognition, sheep, neural circuits, maternal care, neuroanatomy, electrophysiology, reproductive behavior
- MeSH terms
- Animals, Brain, Female, Fertility, Maternal Behavior, Neurons, Olfactory Pathways, Oxytocin, Pregnancy, Reproduction, Sexual Behavior, Animal, Sheep, Smell, Neurotransmitter Agents
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