The DOI matches its Crossref record; 73 of the 85 references it cites were found in a registry or an index, and 1 are not checked yet.
Habitual versus Goal-directed Action Control in Parkinson Disease
Open accessAbstract
This study presents the first direct investigation of the hypothesis that dopamine depletion of the dorsal striatum in mild Parkinson disease leads to impaired stimulus-response habit formation, thereby rendering behavior slow and effortful. However, using an instrumental conflict task, we show that patients are able to rely on direct stimulus-response associations when a goal-directed strategy causes response conflict, suggesting that habit formation is not impaired. If anything our results suggest a disease severity-dependent deficit in goal-directed behavior. These results are discussed in the context of Parkinson disease and the neurobiology of habitual and goal-directed behavior.
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In the citing paper
“one attempt to test this found results that indicated it was goal-directed learning that appeared to be impaired in patients with this neurodegenerative disease (Nelson and Killcross, 2006, de Wit et al., 2011).”
From The role of habit in compulsivity (2016) · cites this paper as de Wit et al., 2011
In the citing paper
“Briefly, the instrumental learning task was developed to distinguish between goal-directed and habit-based learning,19 and has been used successfully in studies to establish habits in both animals and humans.24,41, 42, 43, 44”
From Behavioral and neuroimaging evidence for overreliance on habit learning in alcohol-dependent patients (2013) · cites this paper as [42]
In the citing paper
“Indeed, previous studies have demonstrated that both humans and animals adopt an S–R habitual learning strategy to solve this incongruent trial type.19,41, 42, 43, 44”
From Behavioral and neuroimaging evidence for overreliance on habit learning in alcohol-dependent patients (2013) · cites this paper as [42]
In the citing paper
“In these trials, goal-directed learning is disadvantageous, and performance relies solely on habitual control via direct S–R associations.”
From Behavioral and neuroimaging evidence for overreliance on habit learning in alcohol-dependent patients (2013) · cites this paper as [42]
In the citing paper
“For example, patients with Parkinson's disease show an imbalance between goal-directed and habit learning.42”
From Behavioral and neuroimaging evidence for overreliance on habit learning in alcohol-dependent patients (2013) · cites this paper as [42]
In the citing paper
“They also showed that (goal-directed) performance in a posttraining devaluation test covaried negatively with disease severity, arguing that model-based influences were impaired.”
From Goals and Habits in the Brain (2013) · cites this paper as de Wit et al., 2011
In the citing paper
“They showed that subjects with the disease could solve the task, arguing that habit formation may not have been eliminated.”
From Goals and Habits in the Brain (2013) · cites this paper as de Wit et al., 2011
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Citations
Cites
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
James, W. (1891) · Personality Culture Society · doi:10.1037/11059-000 · Cited by 25,876
Studies of interference in serial verbal reactions
Stroop, J. R. (1935) · Journal of Experimental Psychology · doi:10.1037/h0054651 · Cited by 18,622
Parkinsonism: onset, progression, and mortality
Hoehn, M. M., & Yahr, M. D. (1967) · Neurology · doi:10.1212/wnl.17.5.427 · Cited by 12,107
Dopamine, learning and motivation.
Wise, R. A. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1406 · Cited by 3,379 · cited 2×
“crucially involved in this process (Wise, 2004), and the dopaminergic projection from the substantia nigra to the dorsal striatum has been implicated in the reinforcement”
Unified Parkinson's Disease Rating Scale
(2012) · Springer eBooks · doi:10.1007/springerreference_184495 · Cited by 3,071
Daw, N. D., Niv, Y., & Dayan, P. (2005) · Nature Neuroscience · doi:10.1038/nn1560 · Cited by 2,533
Purposive Behavior in Animals and Men
Rodhom, C., & Tolman, E. C. (1950) · The American Journal of Psychology · doi:10.2307/1418946 · Cited by 2,455
The role of the basal ganglia in habit formation
Yin, H. H., & Knowlton, B. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1919 · Cited by 2,402
Recent developments in Parkinson's disease
Fahn, S., Elton, R., MARSDEN, C. D., Calne, D. B., & Goldstein, M. (1986) · Raven Press eBooks · Cited by 2,306
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning
O'Doherty, J., Dayan, P., Schultz, J., Deichmann, R., Friston, K., & Dolan, R. J. (2004) · Science · doi:10.1126/science.1094285 · Cited by 2,088
By Carrot or by Stick: Cognitive Reinforcement Learning in Parkinsonism
Frank, M. J., Seeberger, L. C., & O'Reilly, R. C. (2004) · Science · doi:10.1126/science.1102941 · Cited by 1,964
Uneven Pattern of Dopamine Loss in the Striatum of Patients with Idiopathic Parkinson's Disease
Kish, S. J., Shannak, K. S., & Hornykiewicz, O. (1988) · New England Journal of Medicine · doi:10.1056/nejm198804073181402 · Cited by 1,945
A neostriatal habit learning system in humans
Knowlton, B. J., Mangels, J. A., & Squire, L. R. (1996) · Science · doi:10.1126/science.273.5280.1399 · Cited by 1,777
Learning and Memory Functions of the Basal Ganglia
Packard, M. G., & Knowlton, B. J. (2002) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.112701.142937 · Cited by 1,717
Differential behavioral effects in frontal lobe disease
Benton, A. (1968) · Neuropsychologia · doi:10.1016/0028-3932(68)90038-9 · Cited by 1,575
Goal-directed instrumental action: contingency and incentive learning and their cortical substrates
Balleine, B. W., & Dickinson, A. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00033-1 · Cited by 1,541
Self-citationYin, H. H., Knowlton, B. J., & Balleine, B. W. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03095.x · Cited by 1,226
Actions and habits: The development of behavioural autonomy
Dickinson, A. (1985) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1985.0010 · Cited by 1,217
Self-citationHold Your Horses: Impulsivity, Deep Brain Stimulation, and Medication in Parkinsonism
Frank, M. J., Samanta, J., Moustafa, A. A., & Sherman, S. J. (2007) · Science · doi:10.1126/science.1146157 · Cited by 1,162
Animal intelligence; experimental studies
Thorndike, E. L. (1911) · doi:10.5962/bhl.title.55072 · Cited by 1,100
Reinforcement, expectancy, and learning.
Bolles, R. C. (1972) · Psychological Review · doi:10.1037/h0033120 · Cited by 1,091
Neurobiology of learning and memory
Delacour, J. (1985) · Neuropsychologia · doi:10.1016/0028-3932(85)90073-9 · Cited by 1,026
Dolan, R. J., & Dayan, P. (2013) · Neuron · doi:10.1016/j.neuron.2013.09.007 · Cited by 977
FRONTAL LOBE DYSFUNCTION IN PARKINSON'S DISEASE
TAYLOR, A. E., Saint‐Cyr, J. A., & Lang, A. E. (1986) · Brain · doi:10.1093/brain/109.5.845 · Cited by 887
A cellular mechanism of reward-related learning
Reynolds, J. N. J., Hyland, B. I., & Wickens, J. R. (2001) · Nature · doi:10.1038/35092560 · Cited by 879
FRONTO-STRIATAL COGNITIVE DEFICITS AT DIFFERENT STAGES OF PARKINSON'S DISEASE
Owen, A. M., James-Galton, M., Leigh, P. N., Summers, B. A., MARSDEN, C. D., Quinn, N. P., Lange, K. W., & Robbins, T. W. (1992) · Brain · doi:10.1093/brain/115.6.1727 · Cited by 876
Animal Intelligence. Experimental Studies
Thorndike, E. L., & Jelliffe (1912) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-191205000-00016 · Cited by 824
A specific role for posterior dorsolateral striatum in human habit learning
Tricomi, E., Balleine, B. W., & O’Doherty, J. P. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06796.x · Cited by 769
Coordination of Actions and Habits in the Medial Prefrontal Cortex of Rats
Killcross, S. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.4.400 · Cited by 748
SAHAKIAN, B. J., MORRIS, R. G., EVENDEN, J. L., HEALD, A., LEVY, R., PHILPOT, M., & ROBBINS, T. W. (1988) · Brain · doi:10.1093/brain/111.3.695 · Cited by 666
Variations in the Sensitivity of Instrumental Responding to Reinforcer Devaluation
Adams, C. D. (1982) · The Quarterly Journal of Experimental Psychology Section B · doi:10.1080/14640748208400878 · Cited by 635
Joel, D., & Weiner, I. (2000) · Neuroscience · doi:10.1016/s0306-4522(99)00575-8 · Cited by 614
INTERNAL VERSUS EXTERNAL CUES AND THE CONTROL OF ATTENTION IN PARKINSON'S DISEASE
BROWN, R. G., & MARSDEN, C. D. (1988) · Brain · doi:10.1093/brain/111.2.323 · Cited by 552
Determining the neural substrates of goal-directed learning in the human brain
Valentin, V. V., Dickinson, A., & O'Doherty, J. P. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.0564-07.2007 · Cited by 529
Self-citationCognitive function in Parkinson's disease: From description to theory
Brown, R. G., & Marsden, C. D. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90058-i · Cited by 475
Yin, H. H., Knowlton, B. J., & Balleine, B. W. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04219.x · Cited by 447
Recent Developments in Parkinson's Disease
Pearce, J. (1986) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.49.7.850-c · Cited by 435
Associative theories of goal-directed behaviour: a case for animal–human translational models
Wit, S., & Dickinson, A. (2009) · Psychological Research Psychologische Forschung · doi:10.1007/s00426-009-0230-6 · Cited by 424
Self-citationThe role of prelimbic cortex in instrumental conditioning
Corbit, L. H., & Balleine, B. W. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.09.023 · Cited by 423
Lesion to the nigrostriatal dopamine system disrupts stimulus-response habit formation
Faure, A., Haberland, U., Condé, F., & Massioui, N. E. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3894-04.2005 · Cited by 402
The ubiquity of model-based reinforcement learning
Doll, B. B., Simon, D. A., & Daw, N. D. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.08.003 · Cited by 380
Cognitive and motor shifting aptitude disorder in Parkinson's disease.
Cools, A. R., van den Bercken, J. H., Horstink, M. W. I. M., van Spaendonck, K. P. M., & Berger, H. J. C. (1984) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.47.5.443 · Cited by 371
Daphna Shohamy, A. (2004) · Brain · doi:10.1093/brain/awh100 · Cited by 355
Brown, R. G., & Marsden, C. D. (1991) · Brain · doi:10.1093/oxfordjournals.brain.a101858 · Cited by 343
A dual operator view of habitual behavior reflecting cortical and striatal dynamics
Smith, K. S., & Graybiel, A. M. (2013) · Neuron · doi:10.1016/j.neuron.2013.05.038 · Cited by 324
Sjoerds, Z., de Wit, S., van den Brink, W., Robbins, T. W., Beekman, A. T. F., Penninx, B. W. J. H., & Veltman, D. J. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.107 · Cited by 312
Self-citationDopamine-dependent frontostriatal planning deficits in early Parkinson's disease.
Owen, A. M., Sahakian, B. J., Hodges, J. R., Summers, B. A., Polkey, C. E., & Robbins, T. W. (1995) · Neuropsychology · doi:10.1037/0894-4105.9.1.126 · Cited by 294
Kimble, G. A., & Perlmuter, L. C. (1970) · Psychological Review · doi:10.1037/h0029782 · Cited by 280
Calculating Consequences: Brain Systems That Encode the Causal Effects of Actions
Tanaka, S. C., Balleine, B. W., & O'Doherty, J. P. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1808-08.2008 · Cited by 268
Purposive Behavior in Animals and Man
Young, P. T., & Tolman, E. C. (1933) · The American Journal of Psychology · doi:10.2307/1414208 · Cited by 250
Smittenaar, P., FitzGerald, T. H. B., Romei, V., Wright, N. D., & Dolan, R. J. (2013) · Neuron · doi:10.1016/j.neuron.2013.08.009 · Cited by 244
Cognitive deficits in Parkinson's disease: A cognitive neuroscience perspective
Robbins, T. W., & Cools, R. (2014) · Movement Disorders · doi:10.1002/mds.25853 · Cited by 235
Self-citationBasal ganglia and dopamine contributions to probabilistic category learning
Shohamy, D., Myers, C. E., Kalanithi, J., & Gluck, M. A. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.07.008 · Cited by 227
de Wit, S., Corlett, P. R., Aitken, M. R., Dickinson, A., & Fletcher, P. C. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1639-09.2009 · Cited by 200
Self-citationRole of the Basal Ganglia in Category Learning: How Do Patients With Parkinson's Disease Learn?
Shohamy, D., Myers, C. E., Onlaor, S., & Gluck, M. A. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.4.676 · Cited by 186
Praamstra, P. (1998) · Brain · doi:10.1093/brain/121.1.167 · Cited by 182
An Implicit Learning Task Activates Medial Temporal Lobe in Patients With Parkinson's Disease.
Moody, T. D., Bookheimer, S. Y., Vanek, Z. F., & Knowlton, B. J. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.2.438 · Cited by 178
The Factors that Induce or Overcome Freezing of Gait in Parkinson’s Disease
Rahman, S., Griffin, H. J., Quinn, N. P., & Jahanshahi, M. (2008) · Behavioural Neurology · doi:10.1155/2008/456298 · Cited by 163
Dopamine and performance in a reinforcement learning task: evidence from Parkinson’s disease
Shiner, T., Seymour, B., Wunderlich, K., Hill, C. S., Bhatia, K. P., Dayan, P., & Dolan, R. J. (2012) · Brain · doi:10.1093/brain/aws083 · Cited by 157
Behavioral and associative effects of differential outcomes in discrimination learning
Urcuioli, P. J. (2005) · Learning & Behavior · doi:10.3758/bf03196047 · Cited by 141
Are dopaminergic neurons selectively vulnerable to Parkinson's disease?
Agid, Y., Ruberg, M., Javoy-Agid, F., Hirsch, É. C., Raisman‐Vozari, R., Vyas, S., Faucheux, B. A., Michel, P. P., Kästner, A., & Blanchard, V. (1993) · PubMed · Cited by 127
Reliance on habits at the expense of goal-directed control following dopamine precursor depletion
de Wit, S., Standing, H. R., DeVito, E. E., Robinson, O. J., Ridderinkhof, K. R., Robbins, T. W., & Sahakian, B. J. (2012) · Psychopharmacology · doi:10.1007/s00213-011-2563-2 · Cited by 105
Stimulus-outcome interactions during instrumental discrimination learning by rats and humans.
de Wit, S., Niry, D., Wariyar, R., Aitken, M. R. F., & Dickinson, A. (2007) · Journal of Experimental Psychology: Animal Behavior Processes · doi:10.1037/0097-7403.33.1.1 · Cited by 93
Self-citationSchad, D. J., Obst, E., Sebold, M., Garbusow, M., Bernhardt, N. R., Javadi, A., Zimmermann, U. S., Smolka, M. N., Heinz, A., Rapp, M. A., et al. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.01450 · Cited by 92
Devaluation and sequential decisions: linking goal-directed and model-based behavior
Friedel, E., Koch, S., Wendt, J., Heinz, A., Deserno, L., & Schlagenhauf, F. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00587 · Cited by 85
Dorsomedial Prefrontal Cortex Resolves Response Conflict in Rats
de Wit, S., Kosaki, Y., Balleine, B. W., & Dickinson, A. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.5175-05.2006 · Cited by 67
Self-citationAcute alcohol impairs human goal-directed action
Hogarth, L., Attwood, A. S., Bate, H. A., & Munafò, M. R. (2012) · Biological Psychology · doi:10.1016/j.biopsycho.2012.02.016 · Cited by 58
Chersi, F., Mirolli, M., Pezzulo, G., & Baldassarre, G. (2012) · Neural Networks · doi:10.1016/j.neunet.2012.11.009 · Cited by 57
Striatum in stimulus–response learning via feedback and in decision making
Hiebert, N. M., Vo, A., Hampshire, A., Owen, A. M., Seergobin, K. N., & MacDonald, P. A. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.07.013 · Cited by 56
Hogarth, L., Field, M., & Rose, A. K. (2012) · Addiction Biology · doi:10.1111/adb.12009 · Cited by 43
Impaired acquisition of goal-directed action in healthy aging
de Wit, S., van de Vijver, I., & Ridderinkhof, K. R. (2014) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/s13415-014-0288-5 · Cited by 41
Self-citationvan Spaendonck, K. P. M., Berger, H. J. C., Horstink, M. W. I. M., Borm, G. F., & Cools, A. R. (1995) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/01688639508402440 · Cited by 39
Griffiths, O., Langdon, R. A., Pelley, M. E. L., & Coltheart, M. (2014) · Cognitive Neuropsychiatry · doi:10.1080/13546805.2014.897601 · Cited by 38
Witt, K., Daniels, C., Daniel, V., Schmitt-Eliassen, J., Volkmann, J., & Deuschl, G. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.04.013 · Cited by 35
Dasgupta, S., Wörgötter, F., & Manoonpong, P. (2014) · Frontiers in Neural Circuits · doi:10.3389/fncir.2014.00126 · Cited by 34
Swainson, R., SENGUPTA, D., Shetty, T., Watkins, L. D., Summers, B. L., Sahakian, B. J., Polkey, C. E., Barker, R., & Robbins, T. W. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.01.028 · Cited by 33
Self-citationDopaminergic modulation of the updating of stimulus–response episodes in Parkinson's disease
Colzato, L. S., van Wouwe, N. C., Hommel, B., Zmigrod, S., Ridderinkhof, K. R., & Wylie, S. A. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.11.034 · Cited by 31
Preservation of function in Parkinson's disease: What's learning got to do with it?
Beeler, J. A. (2011) · Brain Research · doi:10.1016/j.brainres.2011.09.040 · Cited by 29
The Interaction between Discriminative Stimuli and Outcomes during Instrumental Learning
Dickinson, A., & de Wit, S. (2003) · The Quarterly Journal of Experimental Psychology Section B · doi:10.1080/02724990244000223 · Cited by 26
Self-citationResolution of outcome-induced response conflict by humans after extended training
de Wit, S., Ridderinkhof, K. R., Fletcher, P. C., & Dickinson, A. (2012) · Psychological Research · doi:10.1007/s00426-012-0467-3 · Cited by 24
Self-citationColzato, L. S., Zmigrod, S., & Hommel, B. (2013) · Experimental Brain Research · doi:10.1007/s00221-013-3553-x · Cited by 24
Resolution of conflict between goal-directed actions: Outcome encoding and neural control processes.
de Wit, S., Ostlund, S. B., Balleine, B. W., & Dickinson, A. (2009) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/a0014793 · Cited by 19
Self-citationMaudsley, H. (2007) · Cited by 14
Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible?
Lelos, M. J., Dowd, E., & Dunnett, S. B. (2012) · Progress in brain research · doi:10.1016/b978-0-444-59575-1.00006-5 · Cited by 12
Research works printed but not linked: 2
- Mishkin, 1984, Memories and habits: Two neural systems., 65
- Nelson, 1982, National Adult Reading Test (NART) test manual.
Cited by
Sorted by citations
Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease
Redgrave, P., Rodriguez, M., Smith, Y., Rodriguez-Oroz, M. C., Lehericy, S., Bergman, H., Agid, Y., DeLong, M. R., & Obeso, J. A. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2915 · Cited by 1,134
“The importance of formal testing is also highlighted by a recent report that habit formation in an instrumental conflict task was preserved in patients with Parkinson's diseas”
Dolan, R. J., & Dayan, P. (2013) · Neuron · doi:10.1016/j.neuron.2013.09.007 · Cited by 977
Gillan, C. M., Papmeyer, M., Morein-Zamir, S., Sahakian, B. J., Fineberg, N. A., Robbins, T. W., & de Wit, S. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10071062 · Cited by 609
de Wit, S., Watson, P., Harsay, H. A., Cohen, M. X., van de Vijver, I., & Ridderinkhof, K. R. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.1088-12.2012 · Cited by 373
The ubiquity of model-based reinforcement learning
Doll, B. B., Simon, D. A., & Daw, N. D. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.08.003 · Cited by 380
Metadata
- Authors
- de Wit, S., Barker, R. A., Dickinson, A. D., & Cools, R.
- Affiliations
- 1University of Amsterdam, The Netherlands
- University of Cambridge (GB)
- Radboud University Medical Center (NL)
- Venue
- Journal of Cognitive Neuroscience
- Publisher
- MIT Press - Journals
- Published
- 2011-05-01
- Volume
- 23
- Issue
- 5
- Pages
- 1218-1229
- ISSN
- 0898-929X (ISSN-L)
- 1530-8898
- OpenAlex
- W2136439930
- Cited by
- 116
- References
- 74
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 3 · 2023: 4 · 2022: 7 · 2021: 6 · 2020: 7 · 2019: 4 · 2018: 15 · 2017: 11 · 2016: 5 · 2015: 6 · 2014: 13 · 2013: 8 · 2012: 10
- FWCI
- 5.42
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Cognitive Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- UvA-DARE (University of Amsterdam) (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- Fast Grants
- Parkinson's UK (K-0610)
- Universiteit van Amsterdam
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- Parkinson's disease, habitual behavior, goal-directed behavior, dopamine depletion, dorsal striatum, stimulus-response associations, response conflict, disease severity, action control
- MeSH terms
- Aged, Analysis of Variance, Association Learning, Conditioning, Operant, Discrimination Learning, Dopamine, Goals, Habits, Humans, Male, Middle Aged, Parkinson Disease, Reaction Time, Reference Values, Severity of Illness Index, Dopamine Agents, Case-Control Studies, Matched-Pair Analysis, Neostriatum
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