The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity
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“MiR-146a deficiency is also associated with a more severe EAE phenotype (18).”
From Absence of miRNA-146a Differentially Alters Microglia Function and Proteome (2020) · cites this paper as [18]
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“We have previously identified TRAF6 and IRAK1, two adaptor molecules involved in the NF-κB activation pathway, as targets of miR-146a in mouse T cells that mediate miR-146a control of the resolution of T cell acute and chronic inflammatory responses (23, 30).”
BackgroundInfluentialSelf-citationIL-23 drives a pathogenic T cell population that induces autoimmune inflammation
Langrish, C. L., Chen, Y., Blumenschein, W. M., Mattson, J., Basham, B., Sedgwick, J. D., McClanahan, T., Kastelein, R. A., & Cua, D. J. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041257 · Cited by 4,099
Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M., & Stockinger, B. (2006) · Immunity · doi:10.1016/j.immuni.2006.01.001 · Cited by 3,605 · cited 1×
“In particular, multiple genes involved in inducing Th17 differentiation were upregulated in the 2D2-KO effector T cells, especially the genes in the IL-6–mediated Th17 induction pathway (Figure 5B) (27, 28).”
BackgroundTransforming growth factor-β induces development of the TH17 lineage
Mangan, P. R., Harrington, L. E., O'Quinn, D. B., Helms, W. S., Bullard, D. C., Elson, C. O., Hatton, R. D., Wahl, S. M., Schoeb, T. R., & Weaver, C. T. (2006) · Nature · doi:10.1038/nature04754 · Cited by 3,087
Crosstalk in NF-κB Signaling Pathways
Oeckinghaus, A., Hayden, M. S., & Ghosh, S. (2011) · Nature Immunology · doi:10.1038/ni.2065 · Cited by 1,942
Plasticity of CD4+ T Cell Lineage Differentiation
Zhou, L., Chong, M. M. W., & Littman, D. R. (2009) · Immunity · doi:10.1016/j.immuni.2009.05.001 · Cited by 1,551
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
Nurieva, R., Yang, X. O., Martinez, G., Zhang, Y., Panopoulos, A. D., Ma, L., Schluns, K., Tian, Q., Watowich, S. S., Jetten, A. M., et al. (2007) · Nature · doi:10.1038/nature05969 · Cited by 1,466
TH17 cells in development: an updated view of their molecular identity and genetic programming
Dong, C. (2008) · Nature reviews. Immunology · doi:10.1038/nri2295 · Cited by 1,064
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Cited by
Sorted by citations
Creatine uptake regulates CD8 T cell antitumor immunity
Di Biase, S., Ma, X., Wang, X., Yu, J., Wang, Y.-C., Smith, D. J., Zhou, Y., Li, Z., Kim, Y. J., Clarke, N., et al. (2019) · Journal of Experimental Medicine · doi:10.1084/jem.20182044 · Cited by 132
Th17 cell pathogenicity in autoimmune disease
Park, E., & Ciofani, M. (2025) · Experimental & Molecular Medicine · doi:10.1038/s12276-025-01535-9 · Cited by 75
Absence of miRNA-146a Differentially Alters Microglia Function and Proteome
Martin, N. A., Hyrlov, K. H., Elkjaer, M. L., Thygesen, E. K., Wlodarczyk, A., Elbaek, K. J., Aboo, C., Okarmus, J., Benedikz, E., Reynolds, R., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01110 · Cited by 36
Metadata
- Authors
- Li, B., Wang, X., Choi, I. Y., Wang, Y.-C., Liu, S., Pham, A. T., Moon, H., Smith, D. J., Rao, D. S., Boldin, M. P., & Yang, L.
- Venue
- Journal of Clinical Investigation
- Published
- 2017-09-05
- Volume
- 127
- Issue
- 10
- Pages
- 3702-3716
- ISSN
- 0021-9738
- 1558-8238
- Cited by
- 132
- References
- 12
- Language
- en
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