Cited by 366Mindfulness and Compassion InterventionsNeural and Behavioral Psychology StudiesAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index; none of the 72 sources its claims cite is checked for support yet.

The Mindful Brain and Emotion Regulation in Mood Disorders

Open access
Farb, Norman A S, Anderson, Adam K, Segal, Zindel V·2012·The Canadian Journal of Psychiatry

Abstract

Mindfulness involves nonjudgmental attention to present-moment experience. In its therapeutic forms, mindfulness interventions promote increased tolerance of negative affect and improved well-being. However, the neural mechanisms underlying mindful mood regulation are poorly understood. Mindfulness training appears to enhance focused attention, supported by the anterior cingulate cortex and the lateral prefrontal cortex (PFC). In emotion regulation, these PFC changes promote the stable recruitment of a nonconceptual sensory pathway, an alternative to conventional attempts to cognitively reappraise negative emotion. In neural terms, the transition to nonconceptual awareness involves reducing evaluative processing, supported by midline structures of the PFC. Instead, attentional resources are directed toward a limbic pathway for present-moment sensory awareness, involving the thalamus, insula, and primary sensory regions. In patients with affective disorders, mindfulness training provides an alternative to cognitive efforts to control negative emotion, instead directing attention toward the transitory nature of momentary experience. Limiting cognitive elaboration in favour of momentary awareness appears to reduce automatic negative self-evaluation, increase tolerance for negative affect and pain, and help to engender self-compassion and empathy in people with chronic dysphoria.

Overview

Integrity signals

Registry

Crossref · 10.1177/070674371205700203

Cites

77 of 77 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

49 Not checked yet · 35 Own interpretation

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Show all 43 claims

  • Probably not a substantial claim. 8
  • It may state two separate claims as one. 36
41 of 41
  • The paper relies on this without support.

    The neural mechanisms by which mindfulness improves mood regulation are not well understood.

    “However, the neural mechanisms underlying mindful mood regulation are poorly understood.”
    “our understanding of the mechanisms underlying adaptive affect regulation through the practice of mindfulness is still nascent.”
  • The paper relies on this without support.

    Recent clinical studies have validated the efficacy of mindfulness-based interventions.

    “While recent clinical studies have validated the efficacy of these interventions”
2 of 2

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Citations

Cites

Research works printed but not linked: 2

  1. Opsina MB, 2007, Evid Rep Technol Assess, 155, 1
  2. Chambers CD, 2006, J Cogn Neurosci, 18, 444

Cited by

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Metadata

Authors
Farb, N. A. S., Anderson, A. K., & Segal, Z. V.
Affiliations
  • Rotman Research Institute (CA)
  • University of Toronto (CA)
Corresponding author
Farb, Norman A S
Venue
The Canadian Journal of Psychiatry
Published
2012-02
Volume
57
Issue
2
Pages
70-77
ISSN
  • 0706-7437 (ISSN-L)
  • 1497-0015
OpenAlex
W2184525448
Cited by
366
References
77
Citations by year
2026: 18 · 2025: 28 · 2024: 17 · 2023: 34 · 2022: 17 · 2021: 31 · 2020: 31 · 2019: 28 · 2018: 23 · 2017: 22 · 2016: 31 · 2015: 34 · 2014: 21 · 2013: 28 · 2012: 3
FWCI
3.97
Type
journal article
Language
en
Open access
Locations
  • The Canadian Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health
  • Health Canada
  • Canadian Institutes of Health Research (MT81164)
  • National Institute of Mental Health (R34MH087723, R01MH066992, MH 087723)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
mindfulness, emotion regulation, mood disorders, neural mechanisms, anterior cingulate cortex, lateral prefrontal cortex, cognitive reappraisal, self-compassion, empathy, pain tolerance, insula, thalamus
MeSH terms
Attention, Awareness, Brain Mapping, Emotions, Empathy, Humans, Limbic System, Cognitive Behavioral Therapy, Prefrontal Cortex, Meditation, Mood Disorders

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