The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review

Oxytocin increases trust in humans

Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690 · see citing works

The oxytocin receptor system: structure, function, and regulation

Gimpl, G., & Fahrenholz, F. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.629 · Cited by 3,089 · see citing works

Perceptions of epigenetics

Bird, A. (2007) · Nature · doi:10.1038/nature05913 · Cited by 3,011 · see citing works

Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children

Boyd, A., Golding, J., Macleod, J., Lawlor, D. A., Fraser, A., Henderson, J., Molloy, L., Ness, A., Ring, S., & Davey Smith, G. (2013) · International Journal of Epidemiology · doi:10.1093/ije/dys064 · Cited by 2,996 · see citing works

Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress

Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091 · see citing works

Attachment, exploration, and separation: illustrated by the behavior of one-year-olds in a strange situation

Ainsworth, M. D. S., & Bell, S. M. (1970) · Child Development · doi:10.2307/1127388 · Cited by 1,764 · see citing works

Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine

Meyer-Lindenberg, A., Domes, G., Kirsch, P., & Heinrichs, M. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3044 · Cited by 1,688 · see citing works

An integrated model of emotion processes and cognition in social information processing

Lemerise, E. A., & Arsenio, W. F. (2000) · Child Development · doi:10.1111/1467-8624.00124 · Cited by 1,518 · see citing works

Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders.

Guastella, A. J., Einfeld, S. L., Gray, K. M., Rinehart, N. J., Tonge, B. J., Lambert, T. J., & Hickie, I. B. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.020 · Cited by 962 · see citing works

Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors

Neumann, I. D., & Landgraf, R. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.08.004 · Cited by 954 · see citing works

Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans

Rodrigues, S. M., Saslow, L. R., Garcia, N., John, O. P., & Keltner, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909579106 · Cited by 812 · see citing works

Oxytocin attenuates amygdala responses to emotional faces regardless of valence

Domes, G., Heinrichs, M., Gläscher, J., Büchel, C., Braus, D. F., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.03.025 · Cited by 774 · cited 1× · see citing works

Adult attachment predicts maternal brain and oxytocin response to infant cues.

Strathearn, L., Fonagy, P., Amico, J., & Montague, P. R. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.103 · Cited by 773 · see citing works

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

Bell, J., Tsai, P.-C., Yang, T.-P., Pidsley, R., Nisbet, J. P., Glass, D., Mangino, M., Zhai, G., Zhang, F., Valdes, A., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002629 · Cited by 722 · see citing works

Oxytocin Increases Retention of Social Cognition in Autism

Hollander, E., Bartz, J., Chaplin, W., Phillips, A., Sumner, J., Soorya, L., Anagnostou, E., & Wasserman, S. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.030 · Cited by 693 · see citing works

Structure and expression of a human oxytocin receptor

Kimura, T., Tanizawa, O., Mori, K., Brownstein, M., & Okayama, H. (1992) · Nature · doi:10.1038/356526a0 · Cited by 631 · see citing works

Introduction to Research Topic – Binocular Rivalry: A Gateway to Studying Consciousness

Maier, A., Panagiotaropoulos, T. I., Tsuchiya, N., & Keliris, G. A. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00263 · Cited by 629 · see citing works

Developmental origins of disease paradigm: A mechanistic and evolutionary perspective

Gluckman, P. D., & Hanson, M. A. (2004) · Pediatric Research · doi:10.1203/01.pdr.0000135998.08025.fb · Cited by 607 · see citing works

Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

Gregory, S. G., Connelly, J. J., Towers, A. J., Johnson, J., Biscocho, D., Markunas, C. A., Lintas, C., Abramson, R. K., Wright, H. H., Ellis, P., et al. (2009) · BMC Medicine · doi:10.1186/1741-7015-7-62 · Cited by 576 · see citing works

Oxytocin receptor (<i>OXTR</i>) and serotonin transporter (<i>5-HTT</i>) genes associated with observed parenting

Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2008) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsn004 · Cited by 474 · see citing works

Oxytocin and the development of parenting in humans

Gordon, I., Zagoory-Sharon, O., Leckman, J. F., & Feldman, R. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.02.005 · Cited by 469 · see citing works

Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism

Jacob, S., Brune, C. W., Carter, C. S., Leventhal, B. L., Lord, C., & Cook, E. H. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.02.001 · Cited by 425 · see citing works

Sensitive Parenting Is Associated with Plasma Oxytocin and Polymorphisms in the OXTR and CD38 Genes

Feldman, R., Zagoory-Sharon, O., Weisman, O., Schneiderman, I., Gordon, I., Maoz, R., Shalev, I., & Ebstein, R. P. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.12.025 · Cited by 393 · see citing works

Effects of suckling on hypothalamic-pituitary-adrenal axis responses to psychosocial stress in postpartum lactating women

Heinrichs, M., Meinlschmidt, G., Neumann, I., Wagner, S., Kirschbaum, C., Ehlert, U., & Hellhammer, D. H. (2001) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jcem.86.10.7919 · Cited by 386 · see citing works

Oxytocin Pathway Genes: Evolutionary Ancient System Impacting on Human Affiliation, Sociality, and Psychopathology

Feldman, R., Monakhov, M., Pratt, M., & Ebstein, R. P. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.08.008 · Cited by 352 · see citing works

The oxytocin receptor gene (OXTR) is associated with autism spectrum disorder: a meta-analysis

LoParo, D., & Waldman, I. D. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.77 · Cited by 343 · see citing works

Oxytocin enhances the experience of attachment security

Buchheim, A., Heinrichs, M., George, C., Pokorny, D., Koops, E., Henningsen, P., O’Connor, M.-F., & Gündel, H. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.04.002 · Cited by 277 · see citing works

The association of posttraumatic stress disorder and metabolic syndrome: a study of increased health risk in veterans

Heppner, P. S., Crawford, E. F., Haji, U. A., Afari, N., Hauger, R. L., Dashevsky, B. A., Horn, P. S., Nunnink, S. E., & Baker, D. G. (2009) · BMC Medicine · doi:10.1186/1741-7015-7-1 · Cited by 274 · see citing works

Oxytocin receptor gene ( <i>OXTR</i> ) is related to psychological resources

Saphire-Bernstein, S., Way, B. M., Kim, H. S., Sherman, D. K., & Taylor, S. E. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113137108 · Cited by 262 · see citing works

Impact of Maternal Depression Across the First 6 Years of Life on the Child’s Mental Health, Social Engagement, and Empathy: The Moderating Role of Oxytocin

Apter-Levy, Y., Feldman, M., Vakart, A., Ebstein, R. P., & Feldman, R. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12121597 · Cited by 260 · see citing works

Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF) after acute psychosocial stress

Unternaehrer, E., Luers, P., Mill, J., Dempster, E., Meyer, A. H., Staehli, S., Lieb, R., Hellhammer, D. H., & Meinlschmidt, G. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.77 · Cited by 250 · see citing works

Prospects for epigenetic epidemiology

Foley, D. L., Craig, J. M., Morley, R., Olsson, C. J., Dwyer, T., Smith, K., & Saffery, R. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn380 · Cited by 244 · see citing works

Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type

Smith, A. K., Kilaru, V., Kocak, M., Almli, L. M., Mercer, K. B., Ressler, K. J., Tylavsky, F. A., & Conneely, K. N. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-145 · Cited by 239 · see citing works

Methylation of the oxytocin receptor gene and oxytocin blood levels in the development of psychopathy

Dadds, M. R., Moul, C., Cauchi, A., Dobson-Stone, C., Hawes, D. J., Brennan, J., & Ebstein, R. E. (2014) · Development and Psychopathology · doi:10.1017/s0954579413000497 · Cited by 230 · cited 7× · see citing works

Intranasal oxytocin increases fathers’ observed responsiveness during play with their children: A double-blind within-subject experiment

Naber, F., van IJzendoorn, M. H., Deschamps, P., van Engeland, H., & Bakermans-Kranenburg, M. J. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.04.007 · Cited by 222 · see citing works

Evidence of dysregulated peripheral oxytocin release among depressed women

Cyranowski, J. M., Hofkens, T. L., Frank, E., Seltman, H., Cai, H.-M., & Amico, J. A. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318188ade4 · Cited by 220 · see citing works

Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain

Puglia, M. H., Lillard, T. S., Morris, J. P., & Connelly, J. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1422096112 · Cited by 216 · see citing works

Common polymorphism in the oxytocin receptor gene ( <i>OXTR</i> ) is associated with human social recognition skills

Skuse, D. H., Lori, A., Cubells, J. F., Lee, I., Conneely, K. N., Puura, K., Lehtimäki, T., Binder, E. B., & Young, L. J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1302985111 · Cited by 207 · see citing works

Maternal brain response to own baby‐cry is affected by cesarean section delivery

Swain, J. E., Tasgin, E., Mayes, L. C., Feldman, R., Todd Constable, R., & Leckman, J. F. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01963.x · Cited by 206 · see citing works

Oxytocin, ein Vermittler von Antistress, Wohlbefinden, sozialer Interaktion, Wachstum und Heilung/ Oxytocin, a mediator of anti-stress, well-being, social interaction, growth and healing

Uvnäs‐Moberg, K., & Petersson, M. (2005) · Zeitschrift für psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2005.51.1.57 · Cited by 200 · see citing works

DNA Methylation of the Human Oxytocin Receptor Gene Promoter Regulates Tissue-Specific Gene Suppression

Kusui, C., Kimura, T., Ogita, K., Nakamura, H., Matsumura, Y., Koyama, M., Azuma, C., & Murata, Y. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.6024 · Cited by 196 · see citing works

Cerebrospinal fluid and plasma oxytocin concentrations are positively correlated and negatively predict anxiety in children

Carson, D. S., Berquist, S. W., Trujillo, T. H., Garner, J. P., Hannah, S. L., Hyde, S. A., Sumiyoshi, R. D., Jackson, L. P., Moss, J. K., Strehlow, M. C., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.132 · Cited by 196 · see citing works

Oxytocin receptor gene methylation: converging multilevel evidence for a role in social anxiety

Ziegler, C., Dannlowski, U., Bräuer, D., Stevens, S., Laeger, I., Wittmann, H., Kugel, H., Dobel, C., Hurlemann, R., Reif, A., et al. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.2 · Cited by 193 · see citing works

DNA methylation of the oxytocin receptor gene predicts neural response to ambiguous social stimuli

Jack, A., Connelly, J. J., & Morris, J. P. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00280 · Cited by 192 · cited 3× · see citing works

Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study

Cecil, C. A. M., Lysenko, L., Jaffee, S. R., Pingault, J., Smith, R. G., Relton, C. L., Woodward, G., McArdle, W. L., Mill, J. S., & Barker, E. D. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.95 · Cited by 187 · see citing works

Childhood maternal care is associated with DNA methylation of the genes for brain-derived neurotrophic factor ( <i>BDNF</i> ) and oxytocin receptor ( <i>OXTR</i> ) in peripheral blood cells in adult men and women

Unternaehrer, E., Meyer, A. H., Burkhardt, S. C. A., Dempster, E., Staehli, S., Theill, N., Lieb, R., & Meinlschmidt, G. (2015) · Stress · doi:10.3109/10253890.2015.1038992 · Cited by 181 · see citing works

Oxytocin receptor genetic and epigenetic variations: Association with child abuse and adult psychiatric symptoms

Smearman, E. L., Almli, L. M., Conneely, K. N., Brody, G. H., Sales, J. M., Bradley, B., Ressler, K. J., & Smith, A. K. (2016) · Child Development · doi:10.1111/cdev.12493 · Cited by 173 · see citing works

Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies

Lowe, R., Gemma, C., Beyan, H., Hawa, M. I., Bazeos, A., Leslie, R. D., Montpetit, A., Rakyan, V. K., & Ramagopalan, S. V. (2013) · Epigenetics · doi:10.4161/epi.24362 · Cited by 160 · see citing works

Variant in oxytocin receptor gene is associated with amygdala volume

Furman, D. J., Chen, M. C., & Gotlib, I. H. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.12.004 · Cited by 151 · see citing works

Interaction between oxytocin receptor DNA methylation and genotype is associated with risk of postpartum depression in women without depression in pregnancy

Bell, A. F., Carter, C. S., Steer, C. D., Golding, J., Davis, J. M., Steffen, A. D., Rubin, L. H., Lillard, T. S., Gregory, S., Harris, J. C., et al. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00243 · Cited by 124 · see citing works

Oxytocin indexes relational distress following interpersonal harms in women

Tabak, B. A., McCullough, M. E., Szeto, A., Mendez, A. J., & McCabe, P. M. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.07.004 · Cited by 116 · see citing works

Oxytocin receptor DNA methylation in postpartum depression

Kimmel, M., Clive, M. L., Gispen, F. E., Guintivano, J., Brown, T., Cox, O., Beckmann, M. W., Kornhuber, J., Fasching, P. A., Osborne, L. M., et al. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.04.008 · Cited by 111 · see citing works

Polymorphisms in the oxytocin receptor gene are associated with the development of psychopathy

Dadds, M. R., Moul, C., Cauchi, A., Dobson‐Stone, C., Hawes, D. J., Brennan, J., Urwin, R., & Ebstein, R. P. (2013) · Development and Psychopathology · doi:10.1017/s0954579413000485 · Cited by 108 · see citing works

DNA Methylation of Specific CpG Sites in the Promoter Region Regulates the Transcription of the Mouse Oxytocin Receptor

Mamrut, S., Harony‐Nicolas, H., Sood, R., Shahar-Gold, H., Gainer, H., Shi, Y.-J., Barki‐Harrington, L., & Wagner, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056869 · Cited by 102 · see citing works

Differential Methylation of the Oxytocin Receptor Gene in Patients with Anorexia Nervosa: A Pilot Study

Kim, Y.-R., Kim, J.-H., Kim, M. J., & Treasure, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088673 · Cited by 97 · see citing works

The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities

Ng, J. W. Y., Barrett, L. M., Wong, A., Kuh, D. J., Smith, G. D., & Relton, C. L. (2012) · Genome biology · doi:10.1186/gb-2012-13-6-246 · Cited by 97 · see citing works

DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women

Chagnon, Y. C., Potvin, O., Hudon, C., & Préville, M. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00230 · Cited by 96 · see citing works

Prenatal stress exposure, oxytocin receptor gene (OXTR) methylation, and child autistic traits: The moderating role of OXTR rs53576 genotype

Rijlaarsdam, J., van IJzendoorn, M. H., Verhulst, F. C., Jaddoe, V. W. V., Felix, J. F., Tiemeier, H. W., & Bakermans‐Kranenburg, M. J. (2016) · Autism Research · doi:10.1002/aur.1681 · Cited by 89 · see citing works

Epigenetic evidence for involvement of the oxytocin receptor gene in obsessive–compulsive disorder

Cappi, C., Diniz, J. B., Requena, G. D. L., Lourenço, T., Lisbôa, B. C. G., Batistuzzo, M. C., Marques, A. H., Hoexter, M. Q., Pereira, C. A. D. B., Miguel, E. C., et al. (2016) · BMC Neuroscience · doi:10.1186/s12868-016-0313-4 · Cited by 84 · see citing works

Methylation of the oxytocin receptor gene in clinically depressed patients compared to controls: The role of OXTR rs53576 genotype

Reiner, I., Van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., Bleich, S., Beutel, M., & Frieling, H. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.03.012 · Cited by 83 · see citing works

A genomic element within the third intron of the human oxytocin receptor gene may be involved in transcriptional suppression

Mizumoto, Y., Kimura, T., & Ivell, R. (1997) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(97)00195-0 · Cited by 79 · see citing works

Maternal adversities during pregnancy and cord blood oxytocin receptor (<i>OXTR</i>) DNA methylation

Unternaehrer, E., Bolten, M., Nast, I., Staehli, S., Meyer, A. H., Dempster, E., Hellhammer, D. H., Lieb, R., & Meinlschmidt, G. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw051 · Cited by 75 · see citing works

Sex and Diagnosis-Specific Associations Between DNA Methylation of the Oxytocin Receptor Gene With Emotion Processing and Temporal-Limbic and Prefrontal Brain Volumes in Psychotic Disorders

Rubin, L. H., Connelly, J. J., Reilly, J. L., Carter, C. S., Drogos, L. L., Pournajafi‐Nazarloo, H., Ruocco, A. C., Keedy, S., Matthew, I., Tandon, N., et al. (2015) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2015.10.003 · Cited by 72 · see citing works

Oxytocin receptor genotype modulates ventral striatal activity to social cues and response to stressful life events

Loth, E., Poline, J.-B., Thyreau, B., Jia, T., Tao, C., Lourdusamy, A., Stacey, D., Cattrell, A., Desrivières, S., Ruggeri, B., et al. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.07.043 · Cited by 65 · see citing works

The altered promoter methylation of oxytocin receptor gene in autism

Yüksel, M. E., Yücetürk, B., Karataş, Ö. F., Özen, M., & Doğangün, B. (2016) · Journal of Neurogenetics · doi:10.1080/01677063.2016.1202951 · Cited by 64 · see citing works

Brain region-specific methylation in the promoter of the murine oxytocin receptor gene is involved in its expression regulation

Harony-Nicolas, H., Mamrut, S., Brodsky, L., Shahar-Gold, H., Barki-Harrington, L., & Wagner, S. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.10.004 · Cited by 61 · see citing works

The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities

Ng, J., Barrett, L. M., Wong, A., et al. (2012) · Genome biology · doi:10.1186/gb4029 · Cited by 48 · see citing works

Understanding the Oxytocin System and Its Relevance to Psychiatry

Shamay‐Tsoory, S., & Young, L. J. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.10.014 · Cited by 39 · see citing works

Endocrinologic Control of Food Intake

Uvnäs‐Moberg, K. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1990.tb02906.x · Cited by 13 · see citing works

DNA methylation and regulation of gene expression: Guardian of our health

Dhar, G. A., Saha, S., Mitra, P., & Chaudhuri, R. N. (2021) · The Nucleus · doi:10.1007/s13237-021-00367-y · Cited by 252 · see citing works

Childhood maltreatment and DNA methylation: A systematic review

Cecil, C. A. M., Zhang, Y., & Nolte, T. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.02.019 · Cited by 171 · see citing works

Advances in human oxytocin measurement: challenges and proposed solutions

Tabak, B. A., Leng, G., Szeto, A., Parker, K. J., Verbalis, J. G., Ziegler, T. E., Lee, M. R., Neumann, I. D., & Mendez, A. J. (2023) · Molecular Psychiatry · doi:10.1038/s41380-022-01719-z · Cited by 170 · see citing works

Oxytocin and the Neurobiology of Prosocial Behavior

Marsh, N., Marsh, A. A., Lee, M. R., & Hurlemann, R. (2020) · The Neuroscientist · doi:10.1177/1073858420960111 · Cited by 149 · see citing works

The physiology and pharmacology of oxytocin in labor and in the peripartum period

Uvnäs-Moberg, K. (2024) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2023.04.011 · Cited by 118 · see citing works

Developmental programming of oxytocin through variation in early-life stress: Four meta-analyses and a theoretical reinterpretation

Ellis, B. J., Horn, A. J., Carter, C. S., van IJzendoorn, M. H., & Bakermans‐Kranenburg, M. J. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.101985 · Cited by 103 · see citing works

Glucocorticoid Signaling and Epigenetic Alterations in Stress-Related Disorders

Mourtzi, N., Sertedaki, A., & Charmandari, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115964 · Cited by 87 · see citing works

Deciphering and Targeting the ESR2–miR-10a-5p–BDNF Axis in the Prefrontal Cortex: Advancing Postpartum Depression Understanding and Therapeutics

Luo, F., Liu, L., Guo, M., Liang, J., Chen, L., Shi, X., Liu, H., Cheng, Y., & Du, Y. (2024) · Research · doi:10.34133/research.0537 · Cited by 63 · see citing works

Maternal caregiving and DNA methylation in human infants and children: systematic review

Provenzi, L., Brambilla, M., Scotto di Minico, G., Montirosso, R., & Borgatti, R. (2020) · Genes, Brain and Behavior · doi:10.1111/gbb.12616 · Cited by 60 · see citing works

Roles of the Oxytocin Receptor (OXTR) in Human Diseases

Pierzynowska, K., Gaffke, L., Żabińska, M., Cyske, Z., Rintz, E., Wiśniewska, K., Podlacha, M., & Węgrzyn, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043887 · Cited by 61 · see citing works

Oxytocin as Treatment for Social Cognition, Not There Yet

Erdozain, A. M., & Peñagarikano, O. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00930 · Cited by 61 · see citing works

Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies

Kraaijenvanger, E. J., He, Y., Spencer, H., Smith, A. K., Bos, P. A., & Boks, M. P. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.11.016 · Cited by 57 · see citing works

Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: A systematic narrative review

Kohlhoff, J. R., Cibralic, S., Hawes, D. J., & Eapen, V. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104573 · Cited by 50 · see citing works

On social health: history, conceptualization, and population patterning

Doyle, D. M., & Link, B. G. (2024) · Health Psychology Review · doi:10.1080/17437199.2024.2314506 · Cited by 59 · see citing works

DNA methylation differences associated with social anxiety disorder and early life adversity

Wiegand, A., Kreifelts, B., Munk, M. H. J., Geiselhart, N., Ramadori, K. E., MacIsaac, J. L., Fallgatter, A. J., Kobor, M. S., & Nieratschker, V. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01225-w · Cited by 50 · see citing works

Risk Factors for Postpartum Depression Based on Genetic and Epigenetic Interactions

Luo, F., Zhu, Z., Du, Y., Chen, L., & Cheng, Y. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03313-y · Cited by 56 · see citing works

Genetic and peripheral markers of the oxytocin system and parental care jointly support the cross-generational transmission of bonding across three generations

Fujiwara, T., Weisman, O., Ochi, M., Shirai, K., Matsumoto, K., Noguchi, E., & Feldman, R. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.12.004 · Cited by 46 · see citing works

Early life stress and brain plasticity: from molecular alterations to aberrant memory and behavior

Lopatina, O. L., Panina, Y. A., Malinovskaya, N. A., & Salmina, A. B. (2020) · Reviews in the Neurosciences · doi:10.1515/revneuro-2020-0077 · Cited by 44 · see citing works

The Role of Stress in Obsessive-Compulsive Disorder: A Narrative Review

Raposo-Lima, C., & Morgado, P. (2020) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000274 · Cited by 37 · see citing works

Oxytocin receptor gene methylation in male and female PTSD patients and trauma-exposed controls

Nawijn, L., Krzyzewska, I. M., van Zuiden, M., Henneman, P., Koch, S. B. J., Mul, A. N. P. M., Frijling, J. L., Veltman, D. J., Mannens, M. M. A. M., & Olff, M. (2018) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.10.006 · Cited by 38 · see citing works

Reduced DNA methylation of the oxytocin receptor gene is associated with obsessive-compulsive disorder

Park, C. I., Kim, H. W., Jeon, S., Kang, J. I., & Kim, S. J. (2020) · Clinical Epigenetics · doi:10.1186/s13148-020-00890-w · Cited by 38 · see citing works

DNA Methylation of the Oxytocin Receptor Across Neurodevelopmental Disorders

Siu, M. T., Goodman, S. J., Yellan, I., Butcher, D. T., Jangjoo, M., Grafodatskaya, D., Rajendram, R., Lou, Y., Zhang, R., Zhao, C., et al. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04792-x · Cited by 36 · see citing works

Methylation of the OXTR gene in women with anorexia nervosa: Relationship to social behavior

Thaler, L., Brassard, S. L., Booij, L., Kahan, E., McGregor, K., Labbe, A., Israël, M., & Steiger, H. (2019) · European Eating Disorders Review · doi:10.1002/erv.2703 · Cited by 35 · see citing works

Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits – A systematic review

Moerkerke, M., Bonte, M.-L., Daniëls, N., Chubar, V., Alaerts, K., Steyaert, J. G., & Boets, B. (2021) · Research in Autism · doi:10.1016/j.rasd.2021.101785 · Cited by 33 · see citing works

Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders

Towers, A. J., Tremblay, M. W., Chung, L., Li, X.-L., Bey, A. L., Zhang, W., Cao, X., Wang, X., Wang, P., Duffney, L. J., et al. (2018) · JCI Insight · doi:10.1172/jci.insight.120592 · Cited by 34 · see citing works

Genetic and epigenetic architecture of Obsessive-Compulsive Disorder: In search of possible diagnostic and prognostic biomarkers

Bellia, F., Vismara, M. E. M., Annunzi, E., Cifani, C., Benatti, B., Dell’Osso, B. M., & D’Addario, C. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.10.040 · Cited by 32 · see citing works

Dysregulation of the oxytocin receptor gene in Williams syndrome

Kimura, R., Tomiwa, K., Inoüe, R., Suzuki, S., Nakata, M., Awaya, T., Kato, T., Okazaki, S., Heike, T., & Hagiwara, M. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104631 · Cited by 33 · see citing works

Early Life Stress Induced DNA Methylation of Monoamine Oxidases Leads to Depressive-Like Behavior

Xu, Q., Jiang, M. C., Gu, S., Wang, F., & Yuan, B. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.582247 · Cited by 33 · see citing works

Oxytocin inhibits methamphetamine‐associated learning and memory alterations by regulating DNA methylation at the Synaptophysin promoter

Fan, X., Yang, J., Dong, Y., Hou, Y., Liu, S., & Wu, C. (2018) · Addiction Biology · doi:10.1111/adb.12697 · Cited by 33 · see citing works

Nature and nurture? A review of the literature on childhood maltreatment and genetic factors in the pathogenesis of borderline personality disorder

Wilson, N., Robb, E., Gajwani, R., & Minnis, H. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.12.025 · Cited by 29 · see citing works

Childhood Trauma and Epigenetics: State of the Science and Future

Gladish, N., Merrill, S. M., & Kobor, M. S. (2022) · Current Environmental Health Reports · doi:10.1007/s40572-022-00381-5 · Cited by 30 · see citing works

Therapeutic uses of oxytocin in stress-related neuropsychiatric disorders

Zhang, S., Zhang, Y., Shi, D., & Wang, Z. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01173-6 · Cited by 28 · see citing works

Childhood Adversity, Socioeconomic Instability, Oxytocin-Receptor-Gene Methylation, and Romantic-Relationship Support Among Young African American Men

Kogan, S. M., Bae, D., Cho, J., Smith, A. K., & Nishitani, S. (2019) · Psychological Science · doi:10.1177/0956797619854735 · Cited by 25 · see citing works

Low-level lead exposure during development differentially affects neurobehavioral responses in male and female mouse offspring: A longitudinal study

Dinçkol, Ö., Fuentes, B., Tartaglione, A. M., Pino, A., Calamandrei, G., & Ricceri, L. (2022) · NeuroToxicology · doi:10.1016/j.neuro.2022.05.007 · Cited by 25 · see citing works

The Role of Oxytocin in Alzheimer’s Disease and Its Relationship with Social Interaction

Takahashi, J., Yamada, D., Nagano, W., & Saitoh, A. (2023) · Cells · doi:10.3390/cells12202426 · Cited by 25 · see citing works

Peripheral Blood Mononuclear Cell Oxytocin and Vasopressin Receptor Expression Positively Correlates with Social and Behavioral Function in Children with Autism

Voinsky, I., Bennuri, S. C., Svigals, J., Frye, R. E., Rose, S., & Gurwitz, D. (2019) · Scientific Reports · doi:10.1038/s41598-019-49617-9 · Cited by 25 · see citing works

Attachment-related dimensions in the epigenetic era: A systematic review of the human research

Craig, F., Tenuta, F., Rizzato, V., Costabile, A., Trabacca, A., & Montirosso, R. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.03.006 · Cited by 23 · see citing works

Social Environment and Epigenetics

Merrill, S. M., Gladish, N., & Kobor, M. S. (2019) · Current topics in behavioral neurosciences · doi:10.1007/7854_2019_114 · Cited by 23 · see citing works

The role of oxytocin signaling in depression and suicidality in returning war veterans

Warrener, C., Valentin, E. M., Gallin, C., Richey, L., Ross, D. B., Hood, C. J., Lori, A., Cubells, J. F., Rauch, S. A. M., & Rilling, J. K. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.105085 · Cited by 19 · see citing works

Genetic and Epigenetic Alterations in Autism Spectrum Disorder

Oztenekecioglu, B., Mavis, M., Osum, M., & Kalkan, R. (2021) · Global Medical Genetics · doi:10.1055/s-0041-1735540 · Cited by 24 · see citing works

Maternal Diabetes-Induced Suppression of Oxytocin Receptor Contributes to Social Deficits in Offspring

Liu, J., Liang, Y., Jiang, X., Xu, J., Sun, Y., Wang, Z., Lin, L., Niu, Y., Song, S., Zhang, H., et al. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.634781 · Cited by 20 · see citing works

The promiscuity of the oxytocin–vasopressin systems and their involvement in autism spectrum disorder

Borie, A. M., Theofanopoulou, C., & Andari, E. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819973-2.00009-5 · Cited by 18 · see citing works

The impact of the early environment on oxytocin receptor epigenetics and potential therapeutic implications

Nance, M. G., Sullivan, K. M., & Puglia, M. H. (2024) · Pediatric Research · doi:10.1038/s41390-024-03563-z · Cited by 18 · see citing works

Roles of Epigenetics and Glial Cells in Drug-Induced Autism Spectrum Disorder

Csoka, A. B., Kouhen, N. E., Bennani, S., Getachew, B., Aschner, M., & Tizabi, Y. (2024) · Biomolecules · doi:10.3390/biom14040437 · Cited by 16 · see citing works

Pathways linking adverse environments to emerging adults’ substance abuse and depressive symptoms: A prospective analysis of rural African American men

Kogan, S., Bae, D., Cho, J., Smith, A. K., & Nishitani, S. (2020) · Development and Psychopathology · doi:10.1017/s0954579420000632 · Cited by 13 · see citing works

Oxytocin Prevents the Development of 3-NP-Induced Anxiety and Depression in Male and Female Rats: Possible Interaction of OXTR and mGluR2

Khodagholi, F., Maleki, A., Motamedi, F., Mousavi, M. A., Rafiei, S., & Moslemi, M. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-01003-0 · Cited by 17 · see citing works

Aberrant Early in Life Stimulation of the Stress-Response System Affects Emotional Contagion and Oxytocin Regulation in Adult Male Mice

Giovanni Laviola, A., Busdraghi, L. M., Meschino, G. J., Petrella, C., & Fiore, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22095039 · Cited by 17 · see citing works

Cardinal role of the environment in stress induced changes across life stages and generations

Pang, T. Y., Yaeger, J. D. W., Summers, C. H., & Mitra, R. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.01.012 · Cited by 16 · see citing works

Methylation of oxytocin related genes and early life trauma together shape the N170 response to human faces

Lesemann, F. H. P., Spencer, H., Montoya, E. R., Kraaijenvanger, E. J., He, Y., Branje, S., Boks, M. P., & Bos, P. A. (2020) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2020.08.008 · Cited by 14 · see citing works

The role of maternal touch in the association between SLC6A4 methylation and stress response in very preterm infants

Wigley, I. L. C. M., Mascheroni, E., Fontana, C., Giorda, R., Morandi, F., Bonichini, S., McGlone, F., Fumagalli, M., & Montirosso, R. (2021) · Developmental Psychobiology · doi:10.1002/dev.22218 · Cited by 15 · see citing works

Examining the immunoepigenetic-gut microbiome axis in the context of self-esteem among Native Hawaiians and other Pacific Islanders

Becerra, C. Y., Wells, R. K., Kunihiro, B. P., Lee, R. H., Umeda, L., Allan, N. P., Rubas, N. C., McCracken, T., Nunokawa, C. K. L., Lee, M.-H., et al. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1125217 · Cited by 14 · see citing works

A dog's life: Early life histories influence methylation of glucocorticoid (NR3C1) and oxytocin (OXTR) receptor genes, cortisol levels, and attachment styles

Awalt, S. L., Boghean, L., Klinkebiel, D. L., & Strasser, R. (2024) · Developmental Psychobiology · doi:10.1002/dev.22482 · Cited by 13 · see citing works

The association of oxytocin with major depressive disorder: role of confounding effects of antidepressants

Xie, S., Hu, Y., Fang, L., Chen, S., Botchway, B. O. A., Tan, X., Fang, M., & Hu, Z. (2021) · Reviews in the Neurosciences · doi:10.1515/revneuro-2020-0128 · Cited by 14 · see citing works

The interaction between OXTR rs2268493 and perceived maternal care is associated with amygdala–dorsolateral prefrontal effective connectivity during explicit emotion processing

Antonucci, L. A., Pergola, G., Passiatore, R., Taurisano, P., Quarto, T., Dispoto, E., Rampino, A., Bertolino, A., Cassibba, R., & Blasi, G. (2019) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-019-01062-5 · Cited by 12 · see citing works

Cannabidiol improves maternal obesity-induced behavioral, neuroinflammatory and neurochemical dysfunctions in the juvenile offspring

Rodrigues, F. D. S., Jantsch, J., Fraga, G. D. F., Milczarski, V. L. D. C., Dias, V. S., Scheid, C., Merib, J. D. O., Giovernardi, M., & Guedes, R. P. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.04.010 · Cited by 13 · see citing works

Psychopathic Genes: A Multi-level Adaptive Dynamic Modelling Approach

Augustinus, F., Hendrikse, S. C. F., & Jan Treur, A. (2025) · Lecture notes in networks and systems · doi:10.1007/978-3-031-94770-4_38 · Cited by 12 · see citing works

Autism and Williams syndrome: Dissimilar socio-cognitive profiles with similar patterns of abnormal gene expression in the blood

Niego, A., & Benítez‐Burraco, A. (2020) · Autism · doi:10.1177/1362361320965074 · Cited by 12 · see citing works

Epigenetics, Resilience, Protective Factors and Factors Promoting Positive Outcomes: A Scoping Review

de Assis, S. G., Tavares, P. H., Oliveira, N. C. D. S., Serpeloni, F., & Avanci, J. Q. (2025) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.70042 · Cited by 15 · see citing works

Candidate biomarkers from the integration of methylation and gene expression in discordant autistic sibling pairs

Perini, S., Filosi, M., The Italian Autism Network, Allibrio, G., Basadonne, I., Benvenuto, A., Buono, S., Bravaccio, C., Casonato, C., Ceppi, E., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02407-4 · Cited by 12 · see citing works

Epigenetics and Pharmacoepigenetics of Neurodevelopmental and Neuropsychiatric Disorders

Cacabelos, R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813939-4.00022-x · Cited by 11 · see citing works

Oxytocin Receptor Gene Polymorphism in Lactating Dogs

Ogi, A., Naef, V., Santorelli, F. M., Mariti, C., & Gazzano, A. (2021) · Animals · doi:10.3390/ani11113099 · Cited by 11 · see citing works

Effects of human-animal interaction on salivary and urinary oxytocin in children and dogs

Gnanadesikan, G. E., King, K. M., Carranza, E., Flyer, A. C., Ossello, G., Smith, P. G., Steklis, N. G., Steklis, H. D., Carter, C. S., Connelly, J. J., et al. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2024.107147 · Cited by 10 · see citing works

Sex-dependent association between variability in infants’ OXTR methylation at birth and negative affectivity at 3 months

Nazzari, S., Grumi, S., Villa, M., Mambretti, F., Biasucci, G., Decembrino, L., Giacchero, R., Magnani, M. L., Nacinovich, R., Prefumo, F., et al. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105920 · Cited by 10 · see citing works

The Interaction Effect of Parental Rejection and Oxytocin Receptor Gene Polymorphism on Depression: A Cross-Cultural Study in Non-Clinical Samples

Senese, V. P., Shinohara, K., Venuti, P., Bornstein, M. H., Rosanio, V., Nasti, C., Neoh, M. J. Y., Maresca, M., & Esposito, G. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19095566 · Cited by 9 · see citing works

Epigenetics of Aggression

Duclot, F., & Kabbaj, M. (2021) · Current topics in behavioral neurosciences · doi:10.1007/7854_2021_252 · Cited by 9 · see citing works

Effects of Prenatal Phthalate Exposure and Childhood Exercise on Maternal Behaviors in Female Rats at Postpartum: A Role of Oxtr Methylation in the Hypothalamus

Lee, Y.-J., Lin, H., Chaudhary, M. A., Lee, Y., & Wang, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189847 · Cited by 8 · see citing works

OXTR Gene DNA Methylation Levels Are Associated with Discounting Behavior with Untrustworthy Proposers

Anzani, S., Cannito, L., Bellia, F., Domenico, A. D., Dell’Osso, B. M., Palumbo, R., & D’Addario, C. (2022) · Brain Sciences · doi:10.3390/brainsci12010098 · Cited by 8 · see citing works

Vasopressin, and not oxytocin, receptor gene methylation is associated with individual differences in receptive joint attention in chimpanzees ( Pan troglodytes )

Hopkins, W. D., Staes, N., Guevara, E. E., Mulholland, M. M., Sherwood, C. C., & Bradley, B. J. (2023) · Autism Research · doi:10.1002/aur.2895 · Cited by 8 · see citing works

Music's context-dependent influence on oxytocin, social bonding, and emotion regulation: a systematic review

Chu, T.-H., & Tsai, C.-G. (2026) · Frontiers in cognition · doi:10.3389/fcogn.2025.1678665 · Cited by 8 · see citing works

Epigenetic modification of the oxytocin receptor gene is associated with child-parent neural synchrony during competition

Marzoratti, A., Liu, M. E., Krol, K. M., Sjobeck, G. R., Lipscomb, D., Hofkens, T. L., Boker, S. M., Pelphrey, K. A., Connelly, J. J., & Evans, T. M. (2023) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2023.101302 · Cited by 7 · see citing works

Maternal outcomes related to Genetic and epigenetic Variation in the oxytocin system: A scoping review

Weinstein, S. R., Erickson, E. N., Molina, R., & Bell, A. F. (2023) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2023.100209 · Cited by 6 · see citing works

Perspectives of Pitocin administration on behavioral outcomes in the pediatric population: recent insights and future implications

Torres, G., Mourad, M., & Leheste, J. R. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e04047 · Cited by 7 · see citing works

Oxytocin receptor gene methylation as a molecular marker for severity of depressive symptoms in affective disorder patients

Ludwig, B., Carlberg, L., Kienesberger, K., Swoboda, P., Swoboda, M. M. M., Bernegger, A., Koller, R., Inaner, M., Fuxjäger, M., Zotter, M., et al. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-04031-w · Cited by 7 · see citing works

The Role of Epigenetics in OCD: A Multi-order Adaptive Network Model for DNA-Methylation Pathways and the Development of OCD

Huisman, L., Ong, C., van de Werken, M., & Jan Treur, A. (2024) · IFIP advances in information and communication technology · doi:10.1007/978-3-031-63211-2_18 · Cited by 7 · see citing works

The epigenetic regulation of synaptic genes contributes to the etiology of autism

Srančíková, A., Bačová, Z., & Bakoš, J. (2021) · Reviews in the Neurosciences · doi:10.1515/revneuro-2021-0014 · Cited by 7 · see citing works

Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques

Leon, D. D., Nishitani, S., Walum, H., McCormack, K. M., Wilson, M. E., Smith, A. K., Young, L. J., & Sánchez, M. M. (2020) · Hormones and Behavior · doi:10.1016/j.yhbeh.2020.104856 · Cited by 7 · see citing works

Genetic-epigenetic-neuropeptide associations in mood and anxiety disorders: Toward personalized medicine

Gilani, M., Abak, N., & Saberian, M. (2024) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2024.173897 · Cited by 6 · see citing works

Peripheral mRNA Expression and Prognostic Significance of Emotional Stress Biomarkers in Metastatic Breast Cancer Patients

Fiaz, T., Nadeem, M. S., Afzal, O., Altamimi, A. S. A., Alzarea, S. I., Almalki, W. H., Khan, H. A., Ul‐Haq, I., Hanook, S., Kazmi, I. A., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232214097 · Cited by 6 · see citing works

Effects of the Prenatal Administration of Tetanus Toxoid on the Sociability and Explorative Behaviors of Rat Offspring: A Preliminary Study

Sünnetçi, E., Durankuş, F., Albayrak, Y., Erdoğan, M. A., Atasoy, Ö., & Erbaş, O. (2021) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2021.19.1.84 · Cited by 6 · see citing works

Associations between alcohol use and peripheral, genetic, and epigenetic markers of oxytocin in a general sample of young and older adults

Rung, J. M., Kidder, Q. A., Horta, M., Pournajafi‐Nazarloo, H., Carter, C. S., Berry, M. S., & Ebner, N. C. (2022) · Brain and Behavior · doi:10.1002/brb3.2425 · Cited by 6 · see citing works

The potentialities of oxytocin receptor inhibitors for endometriosis therapy

Yarmolinskaya, M. I., Khobets, V. V., Tral, T. G., & Tkachenko, N. N. (2020) · Gynecological Endocrinology · doi:10.1080/09513590.2020.1816722 · Cited by 6 · see citing works

On social health: Conceptualization, Correlates and PatterningPreprint

Doyle, D. M., & Link, B. G. (2022) · doi:10.31234/osf.io/m2ypw · Cited by 6 · see citing works

Integration of epigenomic and genomic data to predict residual feed intake and the feed conversion ratio in dairy sheep via machine learning algorithms

Fonseca, P. A. D. S., Suárez‐Vega, A., Esteban‐Blanco, C., Marina, H., Pelayo, R., Gutiérrez‐Gil, B., & Arranz, J.-J. (2025) · BMC Genomics · doi:10.1186/s12864-025-11520-1 · Cited by 6 · see citing works

Dissecting the heterogeneity of autism spectrum disorder with sensory behavior, brain, and epigenetic factors

Cheong, Y., Bae, J., Lee, S., Ro, J., Okazawa, H., Kosaka, H., & Jung, M. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03566-2 · Cited by 5 · see citing works

Tactile stimulation reverses painful stimuli outcomes via PVN-VTA oxytocin circuitry and dopaminergic regulation

Sun, Y., Qian, W., Zhang, L., Niu, H., Li, L., Li, L., Zhu, Y., Xiao, J., Liu, J., Han, X., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-09208-z · Cited by 5 · see citing works

The role of protective caregiving in epigenetic regulation in human infants

Montirosso, R., Provenzi, L., & Mascheroni, E. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819262-7.00008-8 · Cited by 5 · see citing works

Distinct promoter regions of the oxytocin receptor gene are hypomethylated in Prader-Willi syndrome and in Prader-Willi syndrome associated psychosis

Heseding, H. M., Jahn, K., Eberlein, C. K., Wieting, J., Maier, H. B., Proskynitopoulos, P. J., Glahn, A., Bleich, S., Frieling, H., & Deest, M. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02014-9 · Cited by 5 · see citing works

Acute intranasal oxytocin dose enhances social preference for parents over peers in male but not female peri-adolescent California mice (Peromyscus californicus)

Guoynes, C. D., & Marler, C. A. (2022) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2023.114230 · Cited by 5 · see citing works

Epigenetics of Stress in Farmed Fish

Guinand, B., & Σαμαράς, Α. (2023) · Wiley eBooks · doi:10.1002/9781119821946.ch12 · Cited by 5 · see citing works

Functional characterization of OXTR -associated enhancers

Cintrón, D. L., Sheng, R. R., & Ahituv, N. (2025) · Human Molecular Genetics · doi:10.1093/hmg/ddaf022 · Cited by 4 · see citing works

Exploring the role of OXTR gene methylation in attachment development: A longitudinal study

Cuyvers, B., Ein‐Dor, T., Houbrechts, M., Freson, K., Goossens, L., Noortgate, W. V. D., Leeuwen, K. G. V., Bijttebier, P., Claes, S. J., Turner, J. D., et al. (2024) · Developmental Psychobiology · doi:10.1002/dev.22496 · Cited by 4 · see citing works

Maternal care is associated with neural and behavioral effects of oxytocin administration during empathic accuracy in schizophrenia and controls

Brown, C. K., Coster, L. D., Lee, J., Lin, L. D., Mathalon, D. H., & Woolley, J. D. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2024.107228 · Cited by 4 · see citing works

Oxytocin Receptor Exon III Methylation in the Umbilical Cord Blood of Newborns With Prenatal Exposure to Crack Cocaine

Baptista, T., de Azeredo, L. A., Zaparte, A., Viola, T., Coral, S. C., Nagai, M., Mangone, F. R., Pavanelli, A., Schuch, J., Mardini, V., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.639287 · Cited by 3 · see citing works

Child DNA methylation in a randomised controlled trial of a video-feedback intervention to promote positive parenting and sensitive discipline (VIPP-SD)

Braithwaite, E., Cole, J., Murgatroyd, C., Wright, N., O’Farrelly, C., Barker, B., & Ramchandani, P. G. (2023) · Frontiers in Child and Adolescent Psychiatry · doi:10.3389/frcha.2023.1175299 · Cited by 4 · see citing works

Oxytocin’s impact on the social brain: Individual differences and context shape a core amygdala-mediated mechanism

Leong, I. L., Wang, X., & Wu, H. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106566 · Cited by 4 · see citing works

Oxytocin and Social Function

Wu, W. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.107645 · Cited by 3 · see citing works

Autism and Williams syndrome: dissimilar socio-cognitive profiles with similar patterns of abnormal gene expression in the bloodPreprint

Niego, A., & Benítez‐Burraco, A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.15.992479 · Cited by 2 · see citing works

Understanding face processing in autism spectrum disorder: insights from cognitive neuroscience

Zhang, L., Guan, X., Wang, D., Wang, J., Liu, X., Liu, S., & Ming, D. (2025) · Cognitive Neurodynamics · doi:10.1007/s11571-025-10321-2 · Cited by 2 · see citing works

Revisiting the case for ‘feral’ humans under the light of the human self-domestication hypothesis: Focusing on language

Niego, A., & Benítez‐Burraco, A. (2022) · Biolinguistics · doi:10.5964/bioling.9319 · Cited by 2 · see citing works

Modifications épigénétiques et effets protecteurs de l’environnement socio-affectif de l’enfant : une revue

Soussignan, R. (2023) · Enfance · doi:10.3917/enf2.233.0265 · Cited by 2 · see citing works

Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits – A systematic review

Moerkerke, M., Bonte, M.-L., Daniëls, N., Chubar, V., Alaerts, K., Steyaert, J. G., & Boets, B. (2021) · Research in Autism · doi:10.1016/j.rasd.2021.101785 · Cited by 33 · see citing works

Exploring the relationship between OXTR DNA methylation and temperament in children with neurodevelopmental disabilities

Mascheroni, E., Butti, N., Mambretti, F., Cordolcini, L., Castagna, A., Maucci, V., Citterio, A., Bettinelli, A., & Montirosso, R. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1763938 · Cited by 1 · see citing works

Oxytocin Receptors and Neurobehavior

Kumsta, R., Zang, J. C. S., & Moser, D. (2016) · Epigenetics and human health · doi:10.1007/978-3-319-29901-3_10

Variation in DNA methylation of the oxytocin gene is associated with prosocial, reward-related, decision-making

Kroll, C., Leibold, N. K., Vingerhoets, C., Kenis, G., van den Hove, D., Riedl, A. M., Schruers, K. R. J., & Hernaus, D. (2026) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2026.107815

Epigenetic regulation of the oxytocin receptor gene: implications for behavioral neuroscience

Kumsta, R., Hummel, E., Chen, F. S., & Heinrichs, M. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00083 · Cited by 207 · see citing works