Prenatal Bisphenol A Exposure and Child Behavior in an Inner-City Cohort
Open accessAbstract
Background: Experimental laboratory evidence suggests that bisphenol A (BPA), an endocrine disruptor, is a neurodevelopmental toxicant. However, there have been limited and inconclusive results with respect to sex-specific BPA effects on child behavior. Objective: We examined the association between prenatal BPA exposure and child behavior, adjusting for postnatal BPA exposure and hypothesizing sex-specific effects. Methods: We followed African-American and Dominican women and their children from pregnancy to child’s age 5 years, collecting spot urine samples from the mothers during pregnancy (34 weeks on average) and from children between 3 and 4 years of age to estimate BPA exposure. We assessed child behavior between 3 and 5 years of age using the Child Behavior Checklist (CBCL) and used generalized linear models to test the association between BPA exposure and child behavior, adjusting for potential confounders. Results: The analysis was conducted on 198 children (87 boys and 111 girls). Among boys, high prenatal BPA exposure (highest quartile vs. the lowest three quartiles) was associated with significantly higher CBCL scores (more problems) on Emotionally Reactive [1.62 times greater; 95% confidence interval (CI): 1.13, 2.32] and Aggressive Behavior syndromes (1.29 times greater; 95% CI: 1.09, 1.53). Among girls, higher exposure was associated with lower scores on all syndromes, reaching statistical significance for Anxious/Depressed (0.75 times as high; 95% CI: 0.57, 0.99) and Aggressive Behavior (0.82 times as high; 95% CI: 0.70, 0.97). Conclusion: These results suggest that prenatal exposure to BPA may affect child behavior, and differently among boys and girls.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In a cohort of 198 children ages 3-5, high levels of maternal BPA were associated with altered emotional reactivity including increased aggressive behavior in boys.
“In a cohort of 198 children ages 3–5, high levels of maternal BPA were associated with altered emotional reactivity including increased aggressive behavior in boys [ 136 ].”
From DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders? (2016) · cites this paper as [136]
These boys at 3-5 years of age displayed increased aggressive behavior and their emotionally reactive symptom scores were 1.62 times higher compared with boys with low prenatal BPA concentrations.
“Intriguingly, these boys at 3–5 years of age displayed increased aggressive behavior and their emotionally reactive symptom scores were 1.62 times higher compared with boys with low prenatal BPA concentrations [ 136 ].”
From DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders? (2016) · cites this paper as [136]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
No adjustments are needed for multiple comparisons.
Rothman, K. J. (1990) · Epidemiology · doi:10.1097/00001648-199001000-00010 · Cited by 5,965 · see citing works
Human exposure to bisphenol A (BPA)
Vandenberg, L. N., Hauser, R. B., Marcus, M., Olea, N., & Welshons, W. V. (2007) · Reproductive Toxicology · doi:10.1016/j.reprotox.2007.07.010 · Cited by 2,897 · see citing works
Exposure of the U.S. Population to Bisphenol A and 4- <i>tertiary</i> -Octylphenol: 2003–2004
Calafat, A. M., Ye, X., Wong, L.-Y., Reidy, J. A., & Needham, L. L. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10753 · Cited by 1,743 · see citing works
Self-citationHinshaw, S. P. (1992) · Psychological Bulletin · doi:10.1037/0033-2909.111.1.127 · Cited by 1,636 · see citing works
Bisphenol-A and the Great Divide: A Review of Controversies in the Field of Endocrine Disruption
Vandenberg, L. N., Maffini, M. V., Sonnenschein, C., Rubin, B. S., & Soto, A. M. (2009) · Endocrine Reviews · doi:10.1210/er.2008-0021 · Cited by 1,407 · see citing works
Exemplification of a Method for Scaling Life Events: The PERI Life Events Scale
Dohrenwend, B. S., Askenasy, A. R., Krasnoff, L., & Dohrenwend, B. P. (1978) · Journal of Health and Social Behavior · doi:10.2307/2136536 · Cited by 1,211 · see citing works
In vivo effects of bisphenol A in laboratory rodent studies
Richter, C. A., Birnbaum, L. S., Farabollini, F., Newbold, R. R., Rubin, B. S., Talsness, C. E., Vandenbergh, J. G., Walser-Kuntz, D. R., & vom Saal, F. S. (2007) · Reproductive Toxicology · doi:10.1016/j.reprotox.2007.06.004 · Cited by 1,147 · see citing works
In vitro molecular mechanisms of bisphenol A action.
Wetherill, Y. B., Akingbemi, B. T., Kanno, J., McLachlan, J. A., Nadal, A., Sonnenschein, C., Watson, C. S., Zoeller, R. T., & Belcher, S. M. (2007) · Reproductive Toxicology · doi:10.1016/j.reprotox.2007.05.010 · Cited by 920 · see citing works
Estradiol and the Developing Brain
McCARTHY, M. M. (2008) · Physiological Reviews · doi:10.1152/physrev.00010.2007 · Cited by 885 · see citing works
Perera, F. P., Rauh, V., Tsai, W.-Y., Kinney, P., Camann, D., Barr, D., Bernert, T., Garfinkel, R., Tu, Y.-H., Diaz, D., et al. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.5742 · Cited by 625 · see citing works
Self-citationImpact of Early-Life Bisphenol A Exposure on Behavior and Executive Function in Children
Braun, J. M., Kalkbrenner, A. E., Calafat, A. M., Yolton, K. A., Ye, X., Dietrich, K. N., & Lanphear, B. P. (2011) · PEDIATRICS · doi:10.1542/peds.2011-1335 · Cited by 565 · see citing works
Self-citationNTP‐CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A
Chapin, R. E., Adams, J., Boekelheide, K., Gray, L. E., Hayward, S. W., Lees, P. S. J., Mcintyre, B., Portier, K. M., Schnorr, T. M., Selevan, S. G., et al. (2008) · Birth Defects Research Part B Developmental and Reproductive Toxicology · doi:10.1002/bdrb.20147 · Cited by 504 · see citing works
Zoeller, R. T., Bansal, R., & Parris, C. (2004) · Endocrinology · doi:10.1210/en.2004-1018 · Cited by 501 · see citing works
Prenatal bisphenol A exposure and early childhood behavior.
Braun, J. M., Yolton, K., Dietrich, K. N., Hornung, R., Ye, X., Calafat, A. M., & Lanphear, B. P. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0900979 · Cited by 481 · see citing works
Self-citationTemporal Variability of Urinary Phthalate Metabolite Levels in Men of Reproductive Age
Hauser, R. B., Meeker, J. D., Park, S., Silva, M. J., & Calafat, A. M. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.7212 · Cited by 475 · see citing works
Self-citationEndocrine disruptors and childhood social impairment
Miodovnik, A., Engel, S. M., Zhu, C., Ye, X., Soorya, L. V., Silva, M. J., Calafat, A. M., & Wolff, M. S. (2011) · NeuroToxicology · doi:10.1016/j.neuro.2010.12.009 · Cited by 423 · see citing works
Self-citationYe, X., Kuklenyik, Z., Needham, L. L., & Calafat, A. M. (2005) · Analytical Chemistry · doi:10.1021/ac050390d · Cited by 412 · see citing works
Self-citationTeitelbaum, S. L., Britton, J. A., Calafat, A. M., Ye, X., Silva, M. J., Reidy, J. A., Galvez, M. P., Brenner, B. L., & Wolff, M. S. (2007) · Environmental Research · doi:10.1016/j.envres.2007.09.010 · Cited by 355 · see citing works
Self-citationVariability and predictors of urinary bisphenol A concentrations during pregnancy
Braun, J. M., Kalkbrenner, A. E., Calafat, A. M., Bernert, J. T., Ye, X., Silva, M. J., Barr, D. B., Sathyanarayana, S., & Lanphear, B. P. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1002366 · Cited by 352 · see citing works
Self-citationTemporal Variability and Predictors of Urinary Bisphenol A Concentrations in Men and Women
Mahalingaiah, S., Meeker, J. D., Pearson, K. R., Calafat, A. M., Ye, X., Petrozza, J. C., & Hauser, R. B. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10605 · Cited by 300 · see citing works
Self-citationYe, X., Wong, L.-Y., Bishop, A. M., & Calafat, A. M. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1002701 · Cited by 291 · see citing works
Self-citationSimilarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice: Relevance for Human Exposure
Taylor, J. A., Saal, F. S. V., Welshons, W. V., Drury, B. E., Rottinghaus, G. E., Hunt, P. A., Toutain, P., Laffont, C. M., & VandeVoort, C. A. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.1002514 · Cited by 277 · see citing works
Effects of developmental exposure to bisphenol A on brain and behavior in mice
Palanza, P., Gioiosa, L., Saal, F. S. V., & Parmigiani, S. (2008) · Environmental Research · doi:10.1016/j.envres.2008.07.023 · Cited by 276 · see citing works
Effect of anxiety reduction on children's school performance and social adjustment.
Wood, J. J. (2006) · Developmental Psychology · doi:10.1037/0012-1649.42.2.345 · Cited by 218 · see citing works
The Home Inventory: Review and Reflections
Bradley, R. H. (1994) · Advances in child development and behavior · doi:10.1016/s0065-2407(08)60054-3 · Cited by 214 · see citing works
Tian, Y., Baek, J., Lee, S., & Jang, C. (2010) · Synapse · doi:10.1002/syn.20746 · Cited by 197 · see citing works
Naciff, J. M. (2002) · Toxicological Sciences · doi:10.1093/toxsci/68.1.184 · Cited by 185 · see citing works
Perinatal Exposure to the Estrogenic Pollutant Bisphenol A Affects Behavior in Male and Female Rats
Farabollini, F. (1999) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(99)00136-7 · Cited by 183 · see citing works
Developmental exposure to environmental estrogens alters anxiety and spatial memory in female mice
Ryan, B. C., & Vandenbergh, J. G. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.01.007 · Cited by 180 · see citing works
Poimenova, A., Markaki, E., Rahiotis, C., & Kitraki, E. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.02.051 · Cited by 174 · see citing works
Kawai, K., Nozaki, T., Hiroaki, N., Aou, S., Takii, M., & Kubo, C. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.5440 · Cited by 171 · see citing works
Gross, D. A., Fogg, L., Young, M. A., Ridge, A., Cowell, J. M., Richardson, R., & Sivan, A. B. (2006) · Psychological Assessment · doi:10.1037/1040-3590.18.3.313 · Cited by 168 · see citing works
Prenatal Di(2-ethylhexyl)Phthalate Exposure and Length of Gestation Among an Inner-City Cohort
Whyatt, R. M., Adibi, J. J., Calafat, A. M., Camann, D., Rauh, V., Bhat, H. K., Perera, F. P., Andrews, H., Just, A. C., Hoepner, L., et al. (2009) · PEDIATRICS · doi:10.1542/peds.2009-0325 · Cited by 142 · see citing works
Self-citationPharmacokinetics of bisphenol A in neonatal and adult rhesus monkeys
Doerge, D. R., Twaddle, N. C., Woodling, K. A., & Fisher, J. W. (2010) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2010.07.009 · Cited by 109 · see citing works
Miyagawa, K., Narita, M., Narita, M., Akama, H., & Suzuki, T. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.01.088 · Cited by 108 · see citing works
Nakagami, A., Negishi, T., Kawasaki, K., Imai, N., Nishida, Y., Ihara, T., Kuroda, Y., Yoshikawa, Y., & Koyama, T. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.03.005 · Cited by 63 · see citing works
Xu, X.-H., Wang, Y.-M., Zhang, J., Luo, Q.-Q., Ye, Y.-P., & Ruan, Q. (2010) · Environmental Toxicology and Chemistry · doi:10.1002/etc.18 · Cited by 53 · see citing works
Nakamura, K., Itoh, K., Yoshimoto, K., Sugimoto, T., & Fushiki, S. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.08.021 · Cited by 53 · see citing works
Mizuo, K., Narita, M., Miyagawa, K., Narita, M., Okuno, E., & Suzuki, T. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2003.11.027 · Cited by 42 · see citing works
Myers, C. L., Bour, J. L., Sidebottom, K. J., Murphy, S., & Hakman, M. (2010) · Psychology in the Schools · doi:10.1002/pits.20465 · Cited by 25 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Bisphenol A and human health: A review of the literature
Rochester, J. R. (2013) · Reproductive Toxicology · doi:10.1016/j.reprotox.2013.08.008 · Cited by 2,018 · see citing works
Perera, F. P. (2017) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15010016 · Cited by 1,284 · see citing works
Self-citationEFSA Panel on Food Contact Materials, E. (2015) · EFSA Journal · doi:10.2903/j.efsa.2015.3978 · Cited by 1,026 · see citing works
Early Life Exposure to Endocrine Disrupting Chemicals and Childhood Obesity and Neurodevelopment
Braun, J. M. (2016) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.186 · Cited by 837 · see citing works
The adverse health effects of bisphenol A and related toxicity mechanisms
Ya, M., Liu, H., Wu, J., Yuan, L., Wang, Y., Du, X., Wang, R., Marwa, P. W., Petlulu, P., Chen, X., et al. (2019) · Environmental Research · doi:10.1016/j.envres.2019.108575 · Cited by 829 · see citing works
Endocrine-disrupting chemicals: Implications for human health
Kahn, L. G., Philippat, C., Nakayama, S. F., Slama, R., & Trasande, L. (2020) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(20)30129-7 · Cited by 797 · see citing works
Housing as a determinant of health equity: A conceptual model
Swope, C. B., & Hernández, D. (2019) · Social Science & Medicine · doi:10.1016/j.socscimed.2019.112571 · Cited by 545 · see citing works
Bisphenol A: Food Exposure and Impact on Human Health
Almeida, S., Raposo, A., Almeida‐González, M., & Carrascosa, C. (2018) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12388 · Cited by 518 · see citing works
Kundakovic, M., Gudsnuk, K., Franks, B., Madrid, J., Miller, R. L., Perera, F. P., & Champagne, F. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1214056110 · Cited by 490 · see citing works
Self-citationThe Minderoo-Monaco Commission on Plastics and Human Health
Landrigan, P. J., Raps, H., Cropper, M., Bald, C., Brunner, M., Canonizado, E. M., Charles, D., Chiles, T. C., Donohue, M. J., Enck, J., et al. (2023) · Annals of Global Health · doi:10.5334/aogh.4056 · Cited by 557 · see citing works
Kinch, C. D., Ibhazehiebo, K., Jeong, J.-H., Habibi, H. R., & Kurrasch, D. M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1417731112 · Cited by 485 · see citing works
DNA methylation of BDNF as a biomarker of early-life adversity
Kundakovic, M., Gudsnuk, K., Herbstman, J. B., Tang, D., Perera, F. P., & Champagne, F. A. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408355111 · Cited by 426 · see citing works
Self-citationEnvironmental Endocrine-Disrupting Chemical Exposure: Role in Non-Communicable Diseases
Kumar, M., Sarma, D. K., Shubham, S., Kumawat, M., Verma, V., Prakash, A., & Tiwari, R. R. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.553850 · Cited by 400 · see citing works
Meeker, J. D., Cantonwine, D. E., Rivera-González, L. O., Ferguson, K. K., Mukherjee, B., Calafat, A. M., Ye, X., Toro, L. V. A. D., Crespo-Hernández, N., Jiménez-Velez, B. D., et al. (2013) · Environmental Science & Technology · doi:10.1021/es400510g · Cited by 377 · see citing works
Self-citationThe gestational foundation of sex differences in development and vulnerability
DiPietro, J. A., & Voegtline, K. M. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2015.07.068 · Cited by 316 · see citing works
Prenatal and early childhood bisphenol A concentrations and behavior in school-aged children
Harley, K. G., Gunier, R. B., Kogut, K. R., Johnson, C. B., Bradman, A., Calafat, A. M., & Eskenazi, B. (2013) · Environmental Research · doi:10.1016/j.envres.2013.06.004 · Cited by 314 · see citing works
Self-citationNeuro-toxic and Reproductive Effects of BPA
Santoro, A., Chianese, R., Troisi, J., Richards, S. M., Nori, S. L., Fasano, S., Guida, M., Plunk, E. C., Viggiano, A., Pierantoni, R., et al. (2019) · Current Neuropharmacology · doi:10.2174/1570159x17666190726112101 · Cited by 281 · see citing works
Mustieles, V., D’Cruz, S. C., Couderq, S., Rodríguez‐Carrillo, A., Fini, J., Hofer, T., Steffensen, I., Dirven, H. A. A. M., Barouki, R., Olea, N., et al. (2020) · Environment International · doi:10.1016/j.envint.2020.105811 · Cited by 269 · see citing works
Street, M. E., Angelini, S., Bernasconi, S., Burgio, E., Cassio, A., Catellani, C., Cirillo, F., Deodati, A., Fabbrizi, E., Fanos, V., et al. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19061647 · Cited by 261 · see citing works
Environmental exposures and depression: biological mechanisms and epidemiological evidence
van den Bosch, M., & Meyer-Lindenberg, A. (2019) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-040218-044106 · Cited by 254 · see citing works
Low dose effects of bisphenol A
Vandenberg, L. N., Ehrlich, S., Belcher, S. M., Ben‐Jonathan, N., Dolinoy, D. C., Hugo, E. R., Hunt, P. A., Newbold, R. R., Rubin, B. S., Saili, K. S., et al. (2013) · Endocrine Disruptors · doi:10.4161/endo.26490 · Cited by 238 · see citing works
The Epigenetic Link between Prenatal Adverse Environments and Neurodevelopmental Disorders
Kundaković, M., & Jarić, I. (2017) · Genes · doi:10.3390/genes8030104 · Cited by 227 · see citing works
Prenatal Exposures to Environmental Chemicals and Children’s Neurodevelopment: An Update
Bellinger, D. C. (2013) · Safety and Health at Work · doi:10.5491/shaw.2013.4.1.1 · Cited by 208 · see citing works
Elucidating the links between endocrine disruptors and neurodevelopment
Schug, T. T., Blawas, A. M., Gray, K., Heindel, J. J., & Lawler, C. P. (2015) · Endocrinology · doi:10.1210/en.2014-1734 · Cited by 204 · see citing works
Bisphenol A: Human exposure and neurobehavior
Mustieles, V., Pérez‐Lobato, R., Olea, N., & Fernández, M. F. (2015) · NeuroToxicology · doi:10.1016/j.neuro.2015.06.002 · Cited by 203 · see citing works
Phthalate and bisphenol A exposure among pregnant women in Canada — Results from the MIREC study
Arbuckle, T. E., Davis, K. A., Marro, L., Fisher, M. M., Legrand, M., LeBlanc, A., Gaudreau, É., Foster, W. G., Choeurng, V., & Fraser, W. D. (2014) · Environment International · doi:10.1016/j.envint.2014.02.010 · Cited by 195 · see citing works
Ghassabian, A., & Trasande, L. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00204 · Cited by 194 · see citing works
Consumer Product Chemicals in Indoor Dust: A Quantitative Meta-analysis of U.S. Studies
Mitro, S. D., Dodson, R. E., Singla, V., Adamkiewicz, G., Elmi, A. F., Tilly, M. K., & Zota, A. R. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.6b02023 · Cited by 183 · see citing works
Neurodevelopmental Disorders and Environmental Toxicants: Epigenetics as an Underlying Mechanism
Tran, N. Q. V., & Miyake, K. (2017) · International Journal of Genomics · doi:10.1155/2017/7526592 · Cited by 183 · see citing works
Bisphenol A exposure and children’s behavior: A systematic review
Ejaredar, M., Lee, Y., Roberts, D. J., Sauve, R. S., & Dewey, D. (2016) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/jes.2016.8 · Cited by 170 · see citing works
Perera, F. P., Nolte, E. L. R., Wang, Y., Margolis, A. E., Calafat, A. M., Wang, S., Garcia, W. E., Hoepner, L., Peterson, B. S., Rauh, V., et al. (2016) · Environmental Research · doi:10.1016/j.envres.2016.07.028 · Cited by 171 · see citing works
Self-citationThyroid-disrupting chemicals and brain development: an update
Mughal, B. B., Fini, J., & DEMENEIX, B. A. (2018) · Endocrine Connections · doi:10.1530/ec-18-0029 · Cited by 170 · see citing works
Keil, K. P., & Lein, P. J. (2016) · Environmental Epigenetics · doi:10.1093/eep/dvv012 · Cited by 167 · see citing works
Early-Life Exposure to Polycyclic Aromatic Hydrocarbons and ADHD Behavior Problems
Perera, F. P., Chang, H.-W., Tang, D. L., Roen, E. L., Herbstman, J. B., Margolis, A. E., Huang, T.-J., Miller, R. L., Wang, S., & Rauh, V. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111670 · Cited by 165 · see citing works
Self-citationBisphenol A Metabolites and Bisphenol S in Paired Maternal and Cord Serum
Liu, J., Li, J., Wu, Y., Zhao, Y., Luo, F., Li, S., Yang, L., Moez, E. K., Dinu, I. A., & Martin, J. W. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.6b05718 · Cited by 162 · see citing works
Prenatal Exposure to Nonpersistent Endocrine Disruptors and Behavior in Boys at 3 and 5 Years
Philippat, C., Nakiwala, D., Calafat, A. M., Botton, J., Agostini, M. D., Heude, B., Slama, R., & the EDEN Mother–Child Study Group (2017) · Environmental Health Perspectives · doi:10.1289/ehp1314 · Cited by 162 · see citing works
Self-citationPrenatal influences on temperament development: the role of environmental epigenetics
Gartstein, M. A., & Skinner, M. K. (2018) · Development and Psychopathology · doi:10.1017/s0954579417001730 · Cited by 161 · see citing works
Bisphenol A exposure and behavioral problems among inner city children at 7–9 years of age
Roen, E. L., Wang, Y., Calafat, A. M., Wang, S., Margolis, A. E., Herbstman, J. B., Hoepner, L., Rauh, V., & Perera, F. P. (2015) · Environmental Research · doi:10.1016/j.envres.2015.01.014 · Cited by 163 · see citing works
Self-citationPrenatal bisphenol A exposure and maternally reported behavior in boys and girls
Evans, S. F., Kobrosly, R. W., Barrett, E. S., Thurston, S. W., Calafat, A. M., Weiss, B., Stahlhut, R. W., Yolton, K. A., & Swan, S. H. (2014) · NeuroToxicology · doi:10.1016/j.neuro.2014.10.003 · Cited by 159 · see citing works
Self-citationNeurological Effects of Bisphenol A and its Analogues
Inadera, H. (2015) · International Journal of Medical Sciences · doi:10.7150/ijms.13267 · Cited by 159 · see citing works
Bisphenol-A: Epigenetic Reprogramming and Effects on Reproduction and Behavior
Mileva, G. R., Baker, S., Konkle, A. T. M., & Bielajew, C. H. (2014) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph110707537 · Cited by 160 · see citing works
Arbuckle, T. E., Marro, L., Davis, K. A., Fisher, M. M., Ayotte, P., Bélanger, P., Dumas, P., LeBlanc, A., Bérubé, R., Gaudreau, É., et al. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1408187 · Cited by 152 · see citing works
Mikołajewska, K., Stragierowicz, J., & Gromadzińska, J. (2015) · International Journal of Occupational Medicine and Environmental Health · doi:10.13075/ijomeh.1896.00343 · Cited by 153 · see citing works
Impact of Environmental Pollutants on Gut Microbiome and Mental Health via the Gut–Brain Axis
Singh, S., Sharma, P., Pal, N., Kumawat, M., Shubham, S., Sarma, D. K., Tiwari, R. R., Kumar, M., & Nagpal, R. (2022) · Microorganisms · doi:10.3390/microorganisms10071457 · Cited by 157 · see citing works
ALL OUR SONS: THE DEVELOPMENTAL NEUROBIOLOGY AND NEUROENDOCRINOLOGY OF BOYS AT RISK
Schore, A. N. (2017) · Infant Mental Health Journal · doi:10.1002/imhj.21616 · Cited by 144 · see citing works
Current concepts in neuroendocrine disruption
León‐Olea, M., Martyniuk, C. J., Orlando, E. F., Ottinger, M. A., Rosenfeld, C. S., Wolstenholme, J. T., & Trudeau, V. L. (2014) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2014.02.005 · Cited by 144 · see citing works
Braun, J. M., Muckle, G., Arbuckle, T. E., Bouchard, M. F., Fraser, W. D., Ouellet, E., Séguin, J. R., Oulhote, Y., Webster, G. M., & Lanphear, B. P. (2017) · Environmental Health Perspectives · doi:10.1289/ehp984 · Cited by 141 · see citing works
Human Infancy...and the Rest of the Lifespan
Bornstein, M. H. (2011) · Annual Review of Psychology · doi:10.1146/annurev-psych-120710-100359 · Cited by 133 · see citing works
The association of environmental toxicants and autism spectrum disorders in children
Ye, B. S., Leung, A. O. W., & Wong, M. H. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2017.04.039 · Cited by 133 · see citing works
Mortensen, M. E., Calafat, A. M., Ye, X., Wong, L.-Y., Wright, D. J., Pirkle, J. L., Merrill, L. S., & Moye, J. (2014) · Environmental Research · doi:10.1016/j.envres.2013.12.004 · Cited by 130 · see citing works
Self-citationRochester, J. R., Bolden, A. L., & Kwiatkowski, C. F. (2018) · Environment International · doi:10.1016/j.envint.2017.12.028 · Cited by 130 · see citing works
Developmental neurotoxicity of persistent organic pollutants: an update on childhood outcome
Berghuis, S. A., Bos, A. F., Sauer, P. J. J., & Roze, E. (2015) · Archives of Toxicology · doi:10.1007/s00204-015-1463-3 · Cited by 128 · see citing works
Ashrap, P., Watkins, D. J., Calafat, A. M., Ye, X., Rosario, Z., Brown, P., Vélez-Vega, C. M., Alshawabkeh, A. N., Cordero, J. F., & Meeker, J. D. (2018) · Environment International · doi:10.1016/j.envint.2018.08.020 · Cited by 127 · see citing works
Self-citationMatsuda, S., Matsuzawa, D., Ishii, D., Tomizawa, H., Sutoh, C., Nakazawa, K., Amano, K., Sajiki, J., & Shimizu, E. (2012) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.06.016 · Cited by 122 · see citing works
Casas, M., Forns, J., Martinez, D. R., Avella-García, C. B., Valvi, D., Ballesteros‐Gómez, A., Luque, N., Rubio, S., Júlvez, J., Sunyer, J., et al. (2015) · Environmental Research · doi:10.1016/j.envres.2015.07.024 · Cited by 122 · see citing works
Bisphenol A and phthalate endocrine disruption of parental and social behaviors
Rosenfeld, C. S. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00057 · Cited by 119 · see citing works
Castro, B., Sánchez, P., Torres, J. M., & Ortega, E. (2015) · Environmental Research · doi:10.1016/j.envres.2015.07.001 · Cited by 119 · see citing works
Prenatal exposure to bisphenol A and its alternatives and child neurodevelopment at 2 years
Jiang, Y., Li, J., Xu, S., Zhou, Y. R., Zhao, H., Li, Y., Xiong, C., Sun, X., Liu, H., Liu, W., et al. (2019) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2019.121774 · Cited by 120 · see citing works
Bisphenol A in relation to behavior and learning of school‐age children
Hong, S., Hong, Y., Kim, J., Park, E. J., Shin, M., Kim, B., Yoo, H., Cho, I., Bhang, S., & Cho, S.-C. (2013) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12050 · Cited by 111 · see citing works
Kern, J. K., Geier, D. A., Homme, K. G., King, P. G., Bjørklund, G., Chirumbolo, S., & Geier, M. R. (2017) · Acta Neurobiologiae Experimentalis · doi:10.21307/ane-2017-061 · Cited by 111 · see citing works
Urinary Bisphenol A Levels during Pregnancy and Risk of Preterm Birth
Cantonwine, D. E., Ferguson, K. K., Mukherjee, B., McElrath, T. F., & Meeker, J. D. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1408126 · Cited by 106 · see citing works
Gerona, R. R. L., Pan, J., Zota, A. R., Schwartz, J. M., Friesen, M. W., Taylor, J. A., Hunt, P. A., & Woodruff, T. J. (2016) · Environmental Health · doi:10.1186/s12940-016-0131-2 · Cited by 106 · see citing works
Perinatal exposure to low-dose bisphenol A affects the neuroendocrine stress response in rats
Panagiotidou, E., Zerva, S., Mitsiou, D. J., Alexis, Μ. N., & Kitraki, E. (2013) · Journal of Endocrinology · doi:10.1530/joe-13-0416 · Cited by 105 · see citing works
How does sex matter? Behavior, stress and animal models of neurobehavioral disorders
Palanza, P., & Parmigiani, S. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.037 · Cited by 101 · see citing works
the APrON Study Team, Grohs, M. N., Reynolds, J. E., Liu, J., Martin, J. W., Pollock, T., Lebel, C. A., & Dewey, D. (2019) · Environmental Health · doi:10.1186/s12940-019-0528-9 · Cited by 100 · see citing works
Arbuckle, T. E., Davis, K. A., Boylan, K., Fisher, M. M., & Fu, J. (2016) · NeuroToxicology · doi:10.1016/j.neuro.2016.03.014 · Cited by 99 · see citing works
Stacy, S. L., Papandonatos, G. D., Calafat, A. M., Chen, A., Yolton, K. A., Lanphear, B. P., & Braun, J. M. (2017) · Environment International · doi:10.1016/j.envint.2017.07.021 · Cited by 100 · see citing works
Self-citationBjörnsdotter, M. K., Jonker, W., Legradi, J., Kool, J., & Ballesteros‐Gómez, A. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.05.171 · Cited by 97 · see citing works
Tewar, S., Auinger, P., Braun, J. M., Lanphear, B. P., Yolton, K. A., Epstein, J. N., Ehrlich, S., & Froehlich, T. E. (2016) · Environmental Research · doi:10.1016/j.envres.2016.05.040 · Cited by 99 · see citing works
Perinatal exposure to endocrine disruptors: sex, timing and behavioral endpoints
Palanza, P., Nagel, S. C., Parmigiani, S., & Saal, F. S. V. (2015) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2015.11.017 · Cited by 96 · see citing works
Kaur, K., Chauhan, V. P. S., Gu, F., & Chauhan, A. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.07.030 · Cited by 96 · see citing works
Prolonged Exposure to Bisphenol A from Single Dermal Contact Events
Liu, J., & Martin, J. W. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b03093 · Cited by 95 · see citing works
Guo, Y., Chen, L., Wu, J., Hua, J., Yang, L., Wang, Q., Zhang, W., Lee, J., & Zhou, B. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.09.007 · Cited by 93 · see citing works
Nesan, D., Sewell, L., & Kurrasch, D. M. (2018) · Hormones and Behavior · doi:10.1016/j.yhbeh.2017.12.001 · Cited by 92 · see citing works
Genome–wide microRNA expression profiling in placentas from pregnant women exposed to BPA
Felice, B. D., Manfellotto, F., Palumbo, A., Troisi, J., Zullo, F., Carlo, C. D., Sardo, A. D. S., Stefano, N. D., Ferbo, U., Guida, M., et al. (2015) · BMC Medical Genomics · doi:10.1186/s12920-015-0131-z · Cited by 91 · see citing works
Williams, S. A., Jasarevic, E., Vandas, G. M., Warzak, D. A., Geary, D. C., Ellersieck, M. R., Roberts, R. M., & Rosenfeld, C. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055698 · Cited by 86 · see citing works
Maternal and infant exposure to environmental phenols as measured in multiple biological matrices
Arbuckle, T. E., Weiss, L., Fisher, M. M., Hauser, R. B., Dumas, P., Bérubé, R., Neisa, A., LeBlanc, A., Lang, C., Ayotte, P., et al. (2014) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2014.10.107 · Cited by 86 · see citing works
Exposure to bisphenol A and behavior in school-age children
Pérez‐Lobato, R., Mustieles, V., Calvente, I., Jiménez-Díaz, I., Ramos, R., Caballero‐Casero, N., López-Jiménez, F. J., Rubio, S., Olea, N., & Fernández, M. F. (2015) · NeuroToxicology · doi:10.1016/j.neuro.2015.12.001 · Cited by 84 · see citing works
Hansen, J. B., Bilenberg, N., Timmermann, C. A. G., Jensen, R., Frederiksen, H., Andersson, A., Kyhl, H., & Jensen, T. K. (2021) · Environmental Health · doi:10.1186/s12940-021-00709-y · Cited by 70 · see citing works
Li, Y., Zhang, H., Kuang, H., Fan, R., Cha, C., Li, G., Luo, Z., & Pang, Q. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2017.12.056 · Cited by 80 · see citing works
Prenatal and postnatal bisphenol A exposure and social impairment in 4-year-old children
Lim, Y.-H., Bae, S., Kim, B.-N., Shin, C. H., Lee, Y. A., Kim, J. I., & Hong, Y. (2017) · Environmental Health · doi:10.1186/s12940-017-0289-2 · Cited by 77 · see citing works
Exposures to Endocrine Disrupting Chemicals in Consumer Products—A Guide for Pediatricians
Wong, K. H., & Durrani, T. S. (2017) · Current problems in pediatric and adolescent health care · doi:10.1016/j.cppeds.2017.04.002 · Cited by 77 · see citing works
Guidry, V. T., Longnecker, M. P., Aase, H., Eggesbø, M. Å., Zeiner, P., Reichborn‐Kjennerud, T., Knudsen, G. P., Bertelsen, R. J., Ye, X., Calafat, A. M., et al. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1408325 · Cited by 76 · see citing works
Self-citationAchieving <scp>CLARITY</scp> on bisphenol A, brain and behaviour
Patisaul, H. B. (2020) · Journal of Neuroendocrinology · doi:10.1111/jne.12730 · Cited by 76 · see citing works
Determinants of urinary bisphenol A concentrations in Mexican/Mexican–American pregnant women
Quirós-Alcalá, L., Eskenazi, B., Bradman, A., Ye, X., Calafat, A. M., & Harley, K. G. (2013) · Environment International · doi:10.1016/j.envint.2013.05.016 · Cited by 75 · see citing works
Self-citationCowell, W., Bellinger, D. C., Coull, B. A., Gennings, C., Wright, R. O., & Wright, R. J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0142492 · Cited by 75 · see citing works
Plasma phthalate and bisphenol a levels and oxidant-antioxidant status in autistic children
Kondolot, M., Ozmert, E. N., Ascı, A., Erkekoglu, P., Oztop, D. B., Gumus, H., Kocer-Gumusel, B., & Yurdakok, K. (2016) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2016.03.006 · Cited by 74 · see citing works
Estrogen Signaling as a Therapeutic Target in Neurodevelopmental Disorders
Crider, A., & Pillai, A. (2016) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.116.237412 · Cited by 74 · see citing works
Ji, H., Liang, H., Wang, Z., Miao, M., Wang, X., Zhang, X., Wen, S., Chen, A., Sun, X., & Yuan, W. (2019) · Environment International · doi:10.1016/j.envint.2019.105010 · Cited by 74 · see citing works
Nesan, D., & Kurrasch, D. M. (2019) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021119-034555 · Cited by 73 · see citing works
Salazar, P. L., Villaseca, P., Cisternas, P., & Inestrosa, N. C. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111345 · Cited by 70 · see citing works
Ghassabian, A., Bell, E. M., Ma, W.-L., Sundaram, R., Kannan, K., Louis, G. M. B., & Yeung, E. H. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.09.107 · Cited by 67 · see citing works
Guilbert, A., Rolland, M., Pin, I., Thomsen, C., Sakhi, A. K., Sabaredzovic, A., Slama, R., Guichardet, K., & Philippat, C. (2021) · Environment International · doi:10.1016/j.envint.2021.106697 · Cited by 65 · see citing works
Symeonides, C., Vacy, K., Thomson, S., Tanner, S., Chua, H. K., Dixit, S., Mansell, T., O’Hely, M., Novakovic, B., Herbstman, J. B., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-48897-8 · Cited by 66 · see citing works
Self-citationPrenatal phenolic compounds exposure and neurobehavioral development at 2 and 7years of age
Lin, C., Chien, C.-J., Tsai, M., Hsieh, C., Hsieh, W., & Chen, P. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.06.160 · Cited by 66 · see citing works
Bisphenol A in Chronic Kidney Disease
González‐Parra, E., Herrero, J. A., Elewa, U., Bosch, R. J., Ortíz, A., & Egido, J. (2013) · International Journal of Nephrology · doi:10.1155/2013/437857 · Cited by 65 · see citing works
Rebuli, M. E., Camacho, L., Adonay, M. E., Reif, D. M., Aylor, D. L., & Patisaul, H. B. (2015) · Toxicological Sciences · doi:10.1093/toxsci/kfv163 · Cited by 64 · see citing works
Li, F., Yang, F., Li, D., Tian, Y., Miao, M., Zhang, Y., Ji, H., Yuan, W., & Liang, H. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.137887 · Cited by 63 · see citing works
Rosenfeld, C. S., Sieli, P. T., Warzak, D. A., Ellersieck, M. R., Pennington, K. A., & Roberts, R. M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1220230110 · Cited by 63 · see citing works
Weber, D. N., Hoffmann, R. G., Hoke, E. S., & Tanguay, R. L. (2014) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2015.958419 · Cited by 63 · see citing works
- Authors
- Perera, F., Vishnevetsky, J., Herbstman, J. B., Calafat, A. M., Xiong, W., Rauh, V., & Wang, S.
- Affiliations
- Columbia University (US)
- Centers for Disease Control and Prevention (US)
- Corresponding author
- Perera, Frederica
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-04-27
- Volume
- 120
- Issue
- 8
- Pages
- 1190-1194
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- PMC
- PMC3440080
- OpenAlex
- W2059905660
- Cited by
- 332
- References
- 40
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 20 · 2023: 14 · 2022: 14 · 2021: 22 · 2020: 55 · 2019: 24 · 2018: 24 · 2017: 35 · 2016: 22 · 2015: 38 · 2014: 17 · 2013: 26 · 2012: 3
- FWCI
- 18.55
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- public-domain
- creativecommons.org/licenses/by/4.0/ (vor, 2072 d)
- Locations
- Environmental Health Perspectives (publishedVersion, public-domain)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- Funders
- U.S. Environmental Protection Agency (P30 ES009089, RD832141, R827027, RD834509)
- New York Community Trust
- Educational Foundation of America
- Blanchette Hooker Rockefeller Fund
- Centers for Disease Control and Prevention (ES009089)
- National Institute of Environmental Health Sciences (P01ES009600, R00ES017051, R01ES008977, P30ES009089)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Keywords
- bisphenol A, prenatal exposure, endocrine disruptors, child behavior, sex differences, developmental neurotoxicity, aggression, emotional reactivity, urinary BPA, inner-city children, African American women, Dominican women
- MeSH terms
- Bisphenol A Compounds, Benzhydryl Compounds, Child Behavior, Child, Preschool, Female, Hispanic or Latino, Humans, Male, Phenols, Pregnancy, Prenatal Exposure Delayed Effects, Urban Population, Cohort Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review