Prenatal influences on temperament development: the role of environmental epigenetics
Open accessAbstract
This review summarizes current knowledge and outlines future directions relevant to questions concerning environmental epigenetics and the processes that contribute to temperament development. Links between prenatal adversity, epigenetic programming, and early manifestations of temperament are important in their own right, also informing our understanding of biological foundations for social–emotional development. In addition, infant temperament attributes represent key etiological factors in the onset of developmental psychopathology, and studies elucidating their prenatal foundations expand our understanding of developmental origins of health and disease. Prenatal adversity can take many forms, and this overview is focused on the environmental effects of stress, toxicants, substance use/psychotropic medication, and nutrition. Dysregulation associated with attention-deficit/hyperactivity–disruptive disorders was noted in the context of maternal substance use and toxicant exposures during gestation, as well as stress. Although these links can be made based on the existing literature, currently few studies directly connect environmental influences, epigenetic programming, and changes in brain development/behavior. The chain of events starting with environmental inputs and resulting in alterations to gene expression, physiology, and behavior of the organism is driven by epigenetics. Epigenetics provides the molecular mechanism of how environmental factors impact development and subsequent health and disease, including early brain and temperament development.
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Maternal smoking in pregnancy is associated with epigenetic modifications, including DNA methylation, implicated in deleterious changes to gene expression and processes related to growth and development.
“Maternal smoking in pregnancy has also been associated with epigenetic modifications, including DNA methylation, that are implicated in deleterious changes to gene expression and processes related to growth and development”
From Prenatal nicotine exposure during pregnancy results in adverse neurodevelopmental alterations and neurobehavioral deficits (2023) · cites this paper as [48]
In §III, “Substance Use and Effects of Psychotropic Medication” (page unavailable), the paper reports DNA methylation differences associated with prenatal tobacco exposure. It discusses methylation-mediated gene-expression and developmental changes for prenatal substance exposure more generally, but does not establish that the tobacco-associated methylation changes cause deleterious changes to gene expression or growth and development; it says their clinical significance remains uncertain. (LLM, conf=0.84)
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Cites
High-Resolution Profiling of Histone Methylations in the Human Genome
Barski, A., Cuddapah, S., Cui, K., Roh, T.-Y., Schones, D. E., Wang, Z., Wei, G., Chepelev, I., & Zhao, K. (2007) · Cell · doi:10.1016/j.cell.2007.05.009 · Cited by 6,845 · see citing works
Epigenetic programming by maternal behavior
Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177 · see citing works
(2008) · doi:10.1038/nrg2290 · Cited by 5,199 · see citing works
Handbook of Competence and Motivation
Elliot, A. J., & Dweck, C. S. (2013) · Cited by 4,671 · see citing works
The attention system of the human brain: 20 years after
Petersen, S. E., & Posner, M. I. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062111-150525 · Cited by 3,439 · see citing works
Porges, S. W. (2007) · Biological Psychology · doi:10.1016/j.biopsycho.2006.06.009 · Cited by 3,415 · see citing works
Persistent epigenetic differences associated with prenatal exposure to famine in humans
Heijmans, B. T., Tobi, E. W., Stein, A. D., Putter, H., Blauw, G. J., Susser, E. S., Slagboom, P. E., & Lumey, L. H. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806560105 · Cited by 3,082 · see citing works
Beyond diathesis stress: differential susceptibility to environmental influences
Belsky, J., & Pluess, M. (2009) · Psychological Bulletin · doi:10.1037/a0017376 · Cited by 3,039 · see citing works
Hammen, C. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.143938 · Cited by 2,979 · see citing works
INFANT MORTALITY, CHILDHOOD NUTRITION, AND ISCHAEMIC HEART DISEASE IN ENGLAND AND WALES
BARKER, D. (1986) · The Lancet · doi:10.1016/s0140-6736(86)91340-1 · Cited by 2,892 · see citing works
Gartstein, M. A., & Desmarais, E. (2016) · The SAGE Encyclopedia of Contemporary Early Childhood Education · doi:10.4135/9781483340333.n409 · Cited by 2,188 · see citing works
Self-citationBOYCE, W. T., & ELLIS, B. J. (2005) · Development and Psychopathology · doi:10.1017/s0954579405050145 · Cited by 2,078 · see citing works
Depue, R. A., & Collins, P. F. (1999) · Behavioral and Brain Sciences · doi:10.1017/s0140525x99002046 · Cited by 2,046 · see citing works
Endocrinology of the stress response
Charmandari, E., Tsigos, C., & Chrousos, G. (2005) · Annual Review of Physiology · doi:10.1146/annurev.physiol.67.040403.120816 · Cited by 1,799 · see citing works
Advances in developmental psychology
Lamb, M. E., Brown, A. L., & Rogoff, B. (1981) · Lawrence Erlbaum Associates eBooks · Cited by 1,686 · see citing works
Frontal EEG asymmetry as a moderator and mediator of emotion
Coan, J. A., & Allen, J. J. B. (2004) · Biological Psychology · doi:10.1016/j.biopsycho.2004.03.002 · Cited by 1,426 · see citing works
Behavior Problems in Preschool Children: A Review of Recent Research
Campbell, S. B. (1995) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1995.tb01657.x · Cited by 1,356 · see citing works
Studying infant temperament via the Revised Infant Behavior Questionnaire
Gartstein, M. A., & Rothbart, M. K. (2003) · Infant Behavior and Development · doi:10.1016/s0163-6383(02)00169-8 · Cited by 1,345 · see citing works
Self-citationKohnstamm, G. A., Bates, J. E., & Rothbart, M. K. (1989) · Medical Entomology and Zoology · Cited by 1,299 · see citing works
Prefrontal Brain Asymmetry: A Biological Substrate of the Behavioral Approach and Inhibition Systems
Sutton, S. K., & Davidson, R. J. (1997) · Psychological Science · doi:10.1111/j.1467-9280.1997.tb00413.x · Cited by 1,263 · see citing works
Translating developmental time across mammalian species
Clancy, B., Darlington, R. B., & Finlay, B. L. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00171-3 · Cited by 1,221 · see citing works
Development of individual differences in temperament
Rothbart, M. K., & Derryberry, D. (1981) · Cited by 1,164 · see citing works
Hyde, J. S., Mezulis, A. H., & Abramson, L. Y. (2008) · Psychological Review · doi:10.1037/0033-295x.115.2.291 · Cited by 1,146 · see citing works
The Dutch Famine and Its Long-Term Consequences for Adult Health
Roseboom, T., de Rooij, S., & Painter, R. (2006) · Early Human Development · doi:10.1016/j.earlhumdev.2006.07.001 · Cited by 1,137 · see citing works
Post-Traumatic Stress Disorder
Yehuda, R. (2002) · New England Journal of Medicine · doi:10.1056/nejmra012941 · Cited by 1,134 · see citing works
Wadhwa, P. D., Buß, C., Entringer, S., & Swanson, J. (2009) · Seminars in Reproductive Medicine · doi:10.1055/s-0029-1237424 · Cited by 986 · see citing works
Culpin, M. (1934) · The Lancet · Cited by 971 · see citing works
Putnam, S. P., Gartstein, M. A., & Rothbart, M. K. (2006) · Infant Behavior and Development · doi:10.1016/j.infbeh.2006.01.004 · Cited by 911 · see citing works
Self-citationGUNNAR, M. R., & VAZQUEZ, D. M. (2001) · Development and Psychopathology · doi:10.1017/s0954579401003066 · Cited by 900 · see citing works
Nutrition and the developing brain: nutrient priorities and measurement
Georgieff, M. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.614s · Cited by 885 · see citing works
Early-Life Blockade of the 5-HT Transporter Alters Emotional Behavior in Adult Mice
Ansorge, M. S., Zhou, M., Lira, A., Hen, R., & Gingrich, J. A. (2004) · Science · doi:10.1126/science.1101678 · Cited by 817 · see citing works
Developing a model for adult temperament
Evans, D. E., & Rothbart, M. K. (2007) · Journal of Research in Personality · doi:10.1016/j.jrp.2006.11.002 · Cited by 807 · see citing works
Duffy, J. C. (1977) · American Journal of Psychiatry · doi:10.1176/ajp.134.12.1455-b · Cited by 744 · see citing works
Yehuda, R., Engel, S. M., Brand, S. R., Seckl, J., Marcus, S. M., & Berkowitz, G. S. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0550 · Cited by 711 · see citing works
Buss, C., Davis, E. P., Shahbaba, B., Pruessner, J. C., Head, K., & Sandman, C. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1201295109 · Cited by 652 · see citing works
Davidson, R. J. (1998) · Psychophysiology · doi:10.1017/s0048577298000134 · Cited by 646 · see citing works
Temperament and the development of personality.
Rothbart, M. K., & Ahadi, S. A. (1994) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.103.1.55 · Cited by 635 · see citing works
Child Health, Developmental Plasticity, and Epigenetic Programming
Hochberg, Z., Feil, R., Constância, M., Fraga, M. F., Junien, C., Carel, J., Boileau, P., Bouc, Y. L., Deal, C., Lillycrop, K. A., et al. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0039 · Cited by 631 · see citing works
Self-citationDNA methylation signatures link prenatal famine exposure to growth and metabolism
Tobi, E. W., Goeman, J. J., Monajemi, R., Gu, H., Putter, H., Zhang, Y., Slieker, R. C., Stok, A. P., Thijssen, P. E., Müller, F., et al. (2014) · Nature Communications · doi:10.1038/ncomms6592 · Cited by 630 · see citing works
Prenatal exposure to maternal depression and cortisol influences infant temperament
DAVIS, E. P., GLYNN, L. M., SCHETTER, C. D., HOBEL, C., CHICZ-DEMET, A., & SANDMAN, C. A. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e318047b775 · Cited by 628 · see citing works
Mattson, S. N., & Riley, E. P. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03651.x · Cited by 608 · see citing works
Boys live dangerously in the womb
Eriksson, J. G., Kajantie, E., Osmond, C., Thornburg, K., & Barker, D. J. P. (2010) · American Journal of Human Biology · doi:10.1002/ajhb.20995 · Cited by 590 · see citing works
Neurodevelopment of Children Exposed in Utero to Antidepressant Drugs
Nulman, I., ROVET, J. F., Stewart, D. E., Wolpin, J., Gardner, H. A., Theis, J. G. W., Kulin, N. A., & Koren, G. (1997) · New England Journal of Medicine · doi:10.1056/nejm199701233360404 · Cited by 572 · see citing works
Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related Genes
Vucetic, Z., Kimmel, J. N., Totoki, K., Hollenbeck, E., & Reyes, T. M. (2010) · Endocrinology · doi:10.1210/en.2010-0505 · Cited by 556 · see citing works
The sensitive hare: sublethal effects of predator stress on reproduction in snowshoe hares
Sheriff, M. J., Krebs, C. J., & Boonstra, R. (2009) · Journal of Animal Ecology · doi:10.1111/j.1365-2656.2009.01552.x · Cited by 546 · see citing works
Prenatal stress and long-term consequences: implications of glucocorticoid hormones
Maccari, S., Darnaudéry, M., Morley‐Fletcher, S., Zuena, A. R., Cinque, C., & Reeth, O. V. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(03)00014-9 · Cited by 529 · see citing works
Targeting long non-coding RNA to therapeutically upregulate gene expression
Wahlestedt, C. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd4018 · Cited by 524 · see citing works
Babenko, O., Kovalchuk, I., & Metz, G. A. S. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.11.013 · Cited by 513 · see citing works
Internalizing Disorders in Childhood
Kovács, M., & Devlin, B. (1998) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00303 · Cited by 499 · see citing works
Kundakovic, M., Gudsnuk, K., Franks, B., Madrid, J., Miller, R. L., Perera, F. P., & Champagne, F. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1214056110 · Cited by 490 · see citing works
Genomic imprinting determines methylation of parental alleles in transgenic mice
Reik, W., Collick, A., Norris, M., Barton, S., & Surani, M. (1987) · Nature · doi:10.1038/328248a0 · Cited by 486 · see citing works
Mattson, S. N., & Riley, E. P. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-199804000-00001 · Cited by 486 · see citing works
Early exposure to lead and juvenile delinquency
Dietrich, K. N., Douglas, R. M., Succop, P., Berger, O. G., & Bornschein, R. L. (2001) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(01)00184-2 · Cited by 461 · see citing works
Manikkam, M., Guerrero‐Bosagna, C., Tracey, R., Haque, M. M., & Skinner, M. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031901 · Cited by 451 · see citing works
Self-citationDiethylstilbestrol Revisited: A Review of the Long-Term Health Effects
Giusti, R. M., Iwamoto, K., & Hatch, E. E. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-122-10-199505150-00008 · Cited by 451 · see citing works
Effortful Control: Factor Structure and Relation to Externalizing and Internalizing Behaviors
Murray, K. T., & Kochanska, G. (2002) · Research on Child and Adolescent Psychopathology · doi:10.1023/a:1019821031523 · Cited by 450 · see citing works
Maternal prenatal anxiety and downregulation of placental 11β-HSD2
O’Donnell, K. J., Bugge Jensen, A., Freeman, L., Khalife, N., O’Connor, T. G., & Glover, V. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.09.014 · Cited by 449 · see citing works
A psychobiological approach to the development of temperament.
Rothbart, M. K., Derryberry, D., & Posner, M. I. (1994) · American Psychological Association eBooks · doi:10.1037/10149-003 · Cited by 445 · see citing works
Temperament and the development of personality.
Rothbart, M. K., & Ahadi, S. A. (1994) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.103.1.55 · Cited by 442 · see citing works
Nulman, I., ROVET, J. F., Stewart, D. E., Wolpin, J., Pace‐Asciak, P., Shuhaiber, S., & Koren, G. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.11.1889 · Cited by 440 · see citing works
Nutrition in early life and the programming of adult disease: a review.
Langley-Evans, S. (2015) · Journal of human nutrition and dietetics (Print) · doi:10.1111/jhn.12212 · Cited by 438 · see citing works
The Role of Temperament in the Etiology of Child Psychopathology
Muris, P., & Ollendick, T. H. (2005) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-005-8809-y · Cited by 436 · see citing works
Buss, C., Davis, E. P., Muftuler, L. T., Head, K., & Sandman, C. A. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.07.010 · Cited by 435 · see citing works
Van den Bergh, B. R. H., Van Calster, B., Smits, T., Van Huffel, S., & Lagae, L. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301450 · Cited by 434 · see citing works
Noncoding RNAs and Gene Silencing
Zaratiegui, M., Irvine, D. V., & Martienssen, R. A. (2007) · Cell · doi:10.1016/j.cell.2007.02.016 · Cited by 427 · see citing works
Transgenerational epigenetic imprints on mate preference
Crews, D., Gore, A. C., Hsu, T. S., Dangleben, N. L., Spinetta, M., Schallert, T., Anway, M. D., & Skinner, M. K. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610410104 · Cited by 418 · see citing works
Self-citationTemperament: Individual differences at the interface of biology and behavior.
(1994) · American Psychological Association eBooks · doi:10.1037/10149-000 · Cited by 402 · see citing works
Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation
Lock, L. F., Takagi, N., & Martin, G. R. (1987) · Cell · doi:10.1016/0092-8674(87)90353-9 · Cited by 375 · see citing works
Further Evidence of Relation Between Prenatal Famine and Major Affective Disorder
Brown, A. S., van Os, J., Driessens, C., Hoek, H. W., & Susser, E. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.2.190 · Cited by 371 · see citing works
Effects of prenatal marijuana exposure on child behavior problems at age 10
Goldschmidt, L., Day, N. L., & Richardson, G. A. (2000) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(00)00066-0 · Cited by 361 · see citing works
The functional role of long non-coding RNAs and epigenetics
Cao, J. (2014) · Biological Procedures Online · doi:10.1186/1480-9222-16-11 · Cited by 359 · see citing works
Prenatal Bisphenol A Exposure and Child Behavior in an Inner-City Cohort
Perera, F., Vishnevetsky, J., Herbstman, J. B., Calafat, A. M., Xiong, W., Rauh, V., & Wang, S. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104492 · Cited by 332 · see citing works
Sullivan, E. L., Grayson, B. E., Takahashi, D. L., Robertson, N. D., Maier, A., Bethea, C. L., Smith, M. S., Coleman, K., & Grove, K. L. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5560-09.2010 · Cited by 324 · see citing works
Putnam, S. P., Rothbart, M. K., & Gartstein, M. A. (2008) · Infant and Child Development · doi:10.1002/icd.582 · Cited by 324 · see citing works
Self-citationBeijers, R., Buitelaar, J. K., & de Weerth, C. (2014) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-014-0566-3 · Cited by 321 · see citing works
Maternal Psychological Distress, Prenatal Cortisol, and Fetal Weight
Diego, M. A., Jones, N. A., Field, T., Hernandez-Reif, M., Schanberg, S., Kuhn, C., & Gonzalez-Garcia, A. (2006) · Psychosomatic Medicine · doi:10.1097/01.psy.0000238212.21598.7b · Cited by 302 · see citing works
Neonatal Antidepressant Exposure has Lasting Effects on Behavior and Serotonin Circuitry
Maciąg, D., Simpson, K. L., Coppinger, D., Lu, Y., Wang, Y., Lin, R. C. S., & Paul, I. A. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300823 · Cited by 302 · see citing works
Transgenerational Epigenetic Programming of the Brain Transcriptome and Anxiety Behavior
Skinner, M. K., Anway, M. D., Savenkova, M. I., Gore, A. C., & Crews, D. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003745 · Cited by 293 · see citing works
Self-citationLonigan, C. J., Phillips, B. M., & Hooe, E. S. (2003) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.71.3.465 · Cited by 284 · see citing works
Jacka, F. N., Ystrøm, E., Brantsæter, A. L., Karevold, E., Roth, C., Haugen, M. A., Meltzer, H. M., Schjølberg, S., & Berk, M. (2013) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2013.07.002 · Cited by 284 · see citing works
Maternal Selective Serotonin Reuptake Inhibitor Use During Pregnancy and Newborn Neurobehavior
Zeskind, P. S., & Stephens, L. E. (2004) · PEDIATRICS · doi:10.1542/peds.113.2.368 · Cited by 279 · see citing works
Maternal Cannabis Use Alters Ventral Striatal Dopamine D2 Gene Regulation in the Offspring
DiNieri, J. A., Wang, X., Szutorisz, H., Spano, S., Kaur, J., Casaccia, P., Dow-Edwards, D. L., & Hurd, Y. L. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.06.027 · Cited by 279 · see citing works
Minireview: Stress-related psychiatric disorders with low cortisol levels: A metabolic hypothesis
Yehuda, R., & Seckl, J. (2011) · Endocrinology · doi:10.1210/en.2011-1218 · Cited by 276 · see citing works
Chen, T., Tsujimoto, N., & Li, E. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.20.9048-9058.2004 · Cited by 273 · see citing works
Hompes, T., Izzi, B., Gellens, E., Morreels, M., Fieuws, S., Pexsters, A., Schops, G., Dom, M., Van Bree, R., Freson, K., et al. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.03.009 · Cited by 262 · see citing works
Monk, C. E., Georgieff, M., & Osterholm, E. A. (2012) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12000 · Cited by 260 · see citing works
Giesing, E. R., Suski, C. D., Warner, R. E., & Bell, A. M. (2010) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2010.1819 · Cited by 253 · see citing works
DNA methylation: A mechanism for embedding early life experiences in the genome
Szyf, M., & Bick, J. (2013) · Child Development · doi:10.1111/j.1467-8624.2012.01793.x · Cited by 251 · see citing works
Biochemical effects of corticosteroids on neural tissues
Meyer, J. S. (1985) · Physiological Reviews · doi:10.1152/physrev.1985.65.4.946 · Cited by 247 · see citing works
Maternal posttraumatic stress symptoms and infant emotional reactivity and emotion regulation
Enlow, M. B., Kitts, R. L., Blood, E., Bizarro, A. M., Hofmeister, M., & Wright, R. J. (2011) · Infant Behavior and Development · doi:10.1016/j.infbeh.2011.07.007 · Cited by 242 · see citing works
Behavioral reactivity and approach-withdrawal bias in infancy.
Hane, A. A., Fox, N. A., Henderson, H. A., & Marshall, P. J. (2008) · Developmental Psychology · doi:10.1037/a0012855 · Cited by 242 · see citing works
Sagiv, S. K., Thurston, S. W., Bellinger, D. C., Tolbert, P. E., Altshul, L., & Korrick, S. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwp427 · Cited by 240 · see citing works
Endocrine disruptor induction of epigenetic transgenerational inheritance of disease
Skinner, M. K. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.07.019 · Cited by 239 · see citing works
Self-citationde Vries, A., Holmes, M. C., Heijnis, A., Seier, J. V., van Heerden, J., Louw, J., Wolfe‐Coote, S. A., Meaney, M. J., Levitt, N. S., & Seckl, J. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci30982 · Cited by 238 · see citing works
Association of tobacco and lead exposures with attention-deficit/hyperactivity disorder
Froehlich, T. E., Lanphear, B. P., Auinger, P., Hornung, R., Epstein, J. N., Braun, J., & Kahn, R. S. (2009) · Pediatrics · doi:10.1542/peds.2009-0738 · Cited by 234 · see citing works
The neurobiological basis of temperament: Towards a better understanding of psychopathology
Whittle, S., Allen, N. B., Lubman, D. I., & Yücel, M. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.09.003 · Cited by 224 · see citing works
Sheriff, M. J., Krebs, C. J., & Boonstra, R. (2010) · Ecology · doi:10.1890/09-1108.1 · Cited by 220 · see citing works
Maternal high fat diet consumption during the perinatal period programs offspring behavior
Sullivan, E. L., Nousen, E. K., & Chamlou, K. A. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.07.014 · Cited by 217 · see citing works
The Relationship between Prenatal PCB Exposure and Intelligence (IQ) in 9-Year-Old Children
Stewart, P. W., Lonky, E., Reihman, J., Pagano, J., Gump, B. B., & Darvill, T. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11058 · Cited by 214 · see citing works
Control networks and neuromodulators of early development.
Posner, M. I., Rothbart, M. K., Sheese, B. E., & Voelker, P. (2011) · Developmental Psychology · doi:10.1037/a0025530 · Cited by 212 · see citing works
Ward, H. E. (2000) · Physiology & Behavior · doi:10.1016/s0031-9384(00)00270-5 · Cited by 196 · see citing works
Perinatal high fat diet alters glucocorticoid signaling and anxiety behavior in adulthood
Sasaki, A., de Vega, W. C., St-Cyr, S., Pan, P., & McGowan, P. O. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.02.044 · Cited by 194 · see citing works
Infant Stress Reactivity and Prenatal Alcohol Exposure
Haley, D. W., Handmaker, N. S., & Lowe, J. R. (2006) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00251.x · Cited by 192 · see citing works
Lonigan, C. J., Carey, M. P., & Finch, A. J., Jr. (1994) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.62.5.1000 · Cited by 185 · see citing works
Perinatal Exposure to High-Fat Diet Programs Energy Balance, Metabolism and Behavior in Adulthood
Sullivan, E. L., Smith, M. S., & Grove, K. L. (2010) · Neuroendocrinology · doi:10.1159/000322038 · Cited by 178 · see citing works
A motivational theory of psychopathology.
Fowles, D. C. (1994) · PubMed · Cited by 175 · see citing works
Does moderate drinking harm the fetal brain? Insights from animal models
Valenzuela, C. F., Morton, R. A., Diaz, M. R., & Topper, L. A. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.01.006 · Cited by 172 · see citing works
Prenatal marijuana exposure: Effect on child depressive symptoms at ten years of age
Gray, K. A., Day, N. L., Leech, S. L., & Richardson, G. A. (2005) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2005.03.010 · Cited by 172 · see citing works
Nonhuman Primate Models to Study Anxiety, Emotion Regulation, and Psychopathology
Kalin, N. H., & SHELTONA, S. E. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1301.021 · Cited by 171 · see citing works
Anway, M. D., & Skinner, M. K. (2008) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60553-6 · Cited by 167 · see citing works
Self-citationMaternal high-fat diet in mice programs emotional behavior in adulthood
Peleg-Raibstein, D., Luca, E., & Wolfrum, C. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.05.027 · Cited by 167 · see citing works
Keil, K. P., & Lein, P. J. (2016) · Environmental Epigenetics · doi:10.1093/eep/dvv012 · Cited by 167 · see citing works
DNA methylation signature of human fetal alcohol spectrum disorder
Portales-Casamar, É., Lussier, A. A., Jones, M. J., MacIsaac, J. L., Edgar, R. D., Mah, S. M., Barhdadi, A., Provost, S., Perreault, L. L., Cynader, M. S., et al. (2016) · Epigenetics & Chromatin · doi:10.1186/s13072-016-0074-4 · Cited by 167 · see citing works
Predation risk affects offspring growth via maternal effects
Coslovsky, M., & Richner, H. (2011) · Functional Ecology · doi:10.1111/j.1365-2435.2011.01834.x · Cited by 164 · see citing works
Impact of Prenatal Cocaine Exposure on Child Behavior Problems Through School Age
Bada, H. S., Das, A., Bauer, C. R., Shankaran, S., Lester, B. M., LaGasse, L. L., Hammond, J. A., Wright, L. L., & Higgins, R. D. (2007) · PEDIATRICS · doi:10.1542/peds.2006-1404 · Cited by 160 · see citing works
Abe, H., Hidaka, N., Kawagoe, C., Odagiri, K., Watanabe, Y., Ikeda, T., Ishizuka, Y., Hashiguchi, H., Takeda, R., Nishimori, T., et al. (2007) · Neuroscience Research · doi:10.1016/j.neures.2007.06.1465 · Cited by 157 · see citing works
Breast Cancer in Mothers Given Diethylstilbestrol in Pregnancy
Er, G., Ab, B., Resseguie, L. J., et al. (1984) · New England Journal of Medicine · doi:10.1056/nejm198411293112201 · Cited by 156 · see citing works
Marroun, H. E., Hudziak, J. J., Tiemeier, H. W., Creemers, H. E., Steegers, E. A. P., Jaddoe, V. W. V., Albert Hofman, D., Verhulst, F. C., van den Brink, W., & Huizink, A. C. (2011) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2011.03.004 · Cited by 152 · see citing works
Psychosocial Influences in Dietary Patterns During Pregnancy
Hurley, K. M., Caulfield, L. E., Sacco, L., Costigan, K. A., & DiPietro, J. A. (2005) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2005.03.007 · Cited by 152 · see citing works
Xu, H. J., Bai, L., Collins, J. F., et al. (1999) · Genomics · doi:10.1006/geno.1999.6009 · Cited by 149 · see citing works
Khulan, B., Cooper, W. N., Skinner, B. M., Bauer, J., Owens, S., Prentice, A. M., Bélteki, G., Constância, M., Dunger, D. B., & Affara, N. A. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds026 · Cited by 148 · see citing works
Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring
Olivier, J. D. A., Vallès, A., van Heesch, F., Afrasiab-Middelman, A., Roelofs, J. J. P. M., Jonkers, M., Peeters, E. J., Korte-Bouws, G. A. H., Dederen, J., Kiliaan, A. J., et al. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2299-z · Cited by 148 · see citing works
Gartstein, M. A., & Fagot, B. I. (2003) · Journal of Applied Developmental Psychology · doi:10.1016/s0193-3973(03)00043-1 · Cited by 146 · see citing works
Self-citationLong-term cognitive sequelae of antenatal maternal anxiety: involvement of the orbitofrontal cortex
Mennes, M., Stiers, P. L. J., Lagae, L. G., & den Bergh, B. R. H. V. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.04.003 · Cited by 146 · see citing works
Genomic imprinting in mammals: an interplay between chromatin and DNA methylation?
Feil, R. (1999) · Trends in Genetics · doi:10.1016/s0168-9525(99)01822-3 · Cited by 145 · see citing works
Breast Cancer in Mothers Given Diethylstilbestrol in Pregnancy
(1985) · New England Journal of Medicine · doi:10.1056/nejm198504183121612 · Cited by 143 · see citing works
Novikova, S. I., He, F., Bai, J., Cutrufello, N. J., Lidow, M. S., & Undieh, A. S. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001919 · Cited by 140 · see citing works
Lisboa, S. F. D. S., de Oliveira, P. E. C., Costa, L. C., Venâncio, E. J., & Moreira, E. G. (2007) · Pharmacology · doi:10.1159/000103097 · Cited by 139 · see citing works
Hanley, G. E., Brain, U. M., & Oberlander, T. F. (2013) · Early Human Development · doi:10.1016/j.earlhumdev.2012.12.012 · Cited by 135 · see citing works
Maternal prenatal stress and infant emotional reactivity six months postpartum
Nolvi, S., Karlsson, L., Bridgett, D. J., Korja, R., Huizink, A. C., Kataja, E., & Karlsson, H. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.04.020 · Cited by 135 · see citing works
Cannabis and the developing brain: Insights from behavior
Trezza, V., Cuomo, V., & Vanderschuren, L. J. M. J. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.01.058 · Cited by 131 · see citing works
Prolonged Prenatal Psychotropic Medication Exposure Alters Neonatal Acute Pain Response
Oberlander, T. F., GRUNAU, R. E., Fitzgerald, C., Ellwood, A.-L., Misri, S. K., Rurak, D. W., & Riggs, K. W. (2002) · Pediatric Research · doi:10.1203/00006450-200204000-00008 · Cited by 131 · see citing works
Lonigan, C. J., Carey, M. P., & Finch, A. J., Jr. (1994) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.62.5.1000 · Cited by 131 · see citing works
Lifestyle, Pregnancy and Epigenetic Effects
Barua, S., & Junaid, M. A. (2015) · Epigenomics · doi:10.2217/epi.14.71 · Cited by 129 · see citing works
Leasure, J. L., Giddabasappa, A., Chaney, S., Johnson, J. E., Pothakos, K., Lau, Y., & Fox, D. A. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10862 · Cited by 128 · see citing works
Prenatal exposure to environmental contaminants and behavioural problems at age 7-8years.
Sioen, I., den Hond, E., Nelen, V., van de Mieroop, E., Croes, K., van Larebeke, N., Nawrot, T., & Schoeters, G. (2013) · Environment International · doi:10.1016/j.envint.2013.06.014 · Cited by 128 · see citing works
O’Loan, J., Eyles, D. W., Kesby, J. P., Ko, P., McGrath, J. J., & Burne, T. H. J. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2006.12.006 · Cited by 126 · see citing works
Mutant huntingtin‐impaired degradation of β‐catenin causes neurotoxicity in Huntington's disease
Godin, J. D., Poizat, G., Hickey, M. A., Maschat, F., & Humbert, S. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.117 · Cited by 126 · see citing works
Casas, M., Forns, J., Martinez, D. R., Avella-García, C. B., Valvi, D., Ballesteros‐Gómez, A., Luque, N., Rubio, S., Júlvez, J., Sunyer, J., et al. (2015) · Environmental Research · doi:10.1016/j.envres.2015.07.024 · Cited by 122 · see citing works
The Yugoslavia Prospective Study of Environmental Lead Exposure
Factor-Litvak, P. R., Wasserman, G. A., Kline, J. K., & Graziano, J. N. (1999) · Environmental Health Perspectives · doi:10.1289/ehp.991079 · Cited by 122 · see citing works
Prenatal maternal stress predicts stress reactivity at 2½ years of age: The Iowa Flood Study
Ping, E. Y., Laplante, D. P., Elgbeili, G., Hillerer, K. M., Brunet, A., O’Hara, M. W., & King, S. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.02.015 · Cited by 120 · see citing works
Oberlander, T. F., GRUNAU, R. E., Mayes, L. C., Riggs, W. K., Rurak, D. W., Papsdorf, M., Misri, S. K., & Weinberg, J. (2008) · Early Human Development · doi:10.1016/j.earlhumdev.2008.06.008 · Cited by 120 · see citing works
Response inhibition at 8 and 9 1/2 years of age in children prenatally exposed to PCBs
Stewart, P., Reihman, J., Gump, B. B., Lonky, E., Darvill, T., & Pagano, J. J. (2005) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2005.07.003 · Cited by 119 · see citing works
Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment
Morris, C. V., DiNieri, J. A., Szutorisz, H., & Hurd, Y. L. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07884.x · Cited by 111 · see citing works
DO PEERS AFFECT STUDENT ACHIEVEMENT? EVIDENCE FROM CANADA USING GROUP SIZE VARIATION
Boucher, V., Bramoullé, Y., Djebbari, H., et al. (2012) · Journal of Applied Econometrics · doi:10.1002/jae.2299 · Cited by 110 · see citing works
Sado, T., Okano, M., Li, E., et al. (2004) · Development · doi:10.1242/dev.00995 · Cited by 108 · see citing works
Vessey, M. P., Fairweather, D. V. I., Norman-Smith, B., & Buckley, J. D. (1983) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1983.tb06438.x · Cited by 106 · see citing works
Presence of an epigenetic signature of prenatal cigarette smoke exposure in childhood
Ladd‐Acosta, C., Shu, C., Lee, B. K., Gidaya, N. B., Singer, A. B., Schieve, L. A., Schendel, D., Jones, N., Daniels, J. L., Windham, G. C., et al. (2015) · Environmental Research · doi:10.1016/j.envres.2015.11.014 · Cited by 106 · see citing works
van den Heuvel, M. I., Johannes, M. A., Henrichs, J., & Van den Bergh, B. R. H. (2015) · Early Human Development · doi:10.1016/j.earlhumdev.2014.12.003 · Cited by 105 · see citing works
Prenatal Smoke Exposure and Genomic DNA Methylation in a Multiethnic Birth Cohort
Flom, J. D., Ferris, J. S., Liao, Y., Tehranifar, P., Belessiotis‐Richards, C., Cho, Y. H., González, K., Santella, R. M., & Terry, M. B. (2011) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-11-0553 · Cited by 104 · see citing works
Maccari, S., Polese, D., Reynaert, M., Amici, T., Morley‐Fletcher, S., & Fagioli, F. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.05.042 · Cited by 101 · see citing works
Murawski, N. J. (2015) · Alcohol research · doi:10.35946/arcr.v37.1.07 · Cited by 100 · see citing works
Introduction to the Special Section on Epigenetics
Lester, B. M., Conradt, E. D., & Marsit, C. J. (2016) · Child Development · doi:10.1111/cdev.12489 · Cited by 100 · see citing works
Trofimova, I., & Robbins, T. (2016) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.03.008 · Cited by 98 · see citing works
Associative DNA Methylation Changes in Children with Prenatal Alcohol Exposure
Laufer, B. I., Kapalanga, J., Castellani, C. A., Chater‐Diehl, E., Yan, L., & Singh, S. M. (2015) · Epigenomics · doi:10.2217/epi.15.60 · Cited by 97 · see citing works
Prenatal stress and depression associated neuronal development in neonates
Fatima, M., Srivastav, S., & Mondal, A. C. (2017) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2017.04.001 · Cited by 97 · see citing works
Selective Serotonin Reuptake Inhibitors Affect Neurobehavioral Development in the Human Fetus
Mulder, E. J. H., Ververs, T. F., de Heus, R., & Visser, G. H. A. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.67 · Cited by 96 · see citing works
Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat
Colciago, A., Casati, L., Mornati, O., Vergoni, A. V., Santagostino, A., Celotti, F., & Negri‐Cesi, P. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.04.023 · Cited by 95 · see citing works
Deppermann, S., Storchak, H., Fallgatter, A. J., & Ehlis, A. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.08.037 · Cited by 95 · see citing works
Barua, S., Chadman, K. K., Kuizon, S., Buenaventura, D. F., Stapley, N. W., Felicia, R., Begum, U. A. M., Guariglia, S. R., Brown, W. T., & Junaid, M. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101674 · Cited by 94 · see citing works
Palanza, P., Parmigiani, S., & Saal, F. S. V. (2001) · Hormones and Behavior · doi:10.1006/hbeh.2001.1697 · Cited by 94 · see citing works
Non‐coding RNAs and their epigenetic regulatory mechanisms
Zhou, H., Hu, H., & Lai, M. (2010) · Biology of the Cell · doi:10.1042/bc20100029 · Cited by 94 · see citing works
DNA methylation patterns in newborns exposed to tobacco in utero
Ivorra, C., Fraga, M. F., Bayón, G. F., Fernández, A. F., García-Vicent, C., Chaves, F. J., Redón, J., & Lurbe, E. (2015) · Journal of Translational Medicine · doi:10.1186/s12967-015-0384-5 · Cited by 93 · see citing works
Delaney‐Black, V., Covington, C. Y., NORDSTROM, B., Ager, J. W., Janisse, J. J., Hannigan, J. H., Chiodo, L. M., & Sokol, R. J. (2004) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200408000-00005 · Cited by 92 · see citing works
Alpár, A., Marzo, V. D., & Harkany, T. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.09.009 · Cited by 91 · see citing works
Epigenetic modification of <i>OXT</i> and human sociability
Haas, B. W., Filkowski, M. M., Cochran, R. N., Denison, L., Ishak, A., Nishitani, S., & Smith, A. K. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1602809113 · Cited by 91 · see citing works
Transplacental and Lactational Transfer of p,p′-DDE in Sprague–Dawley Rats
Li, Y., Gazi, E., Archibeque-Engle, S., et al. (1999) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1999.8673 · Cited by 90 · see citing works
Ostlund, B. D., Conradt, E. D., Crowell, S. E., Tyrka, A. R., Marsit, C. J., & Lester, B. M. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00147 · Cited by 89 · see citing works
Fetal Serotonin Signaling: Setting Pathways for Early Childhood Development and Behavior
Oberlander, T. F. (2012) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2012.04.009 · Cited by 88 · see citing works
Hurricane Katrina-Related Maternal Stress, Maternal Mental Health, and Early Infant Temperament
Tees, M. T., Harville, E. W., Xiong, X., Buekens, P. M., Pridjian, G. C., & Elkind-Hirsch, K. E. (2009) · Maternal and Child Health Journal · doi:10.1007/s10995-009-0486-x · Cited by 87 · see citing works
Epigenetic histone modification regulates developmental lead exposure induced hyperactivity in rats.
Luo, M., Xu, Y., Cai, R., Tang, Y., Ge, M.-M., Liu, Z.-H., Xu, L., Hu, F., Ruan, D.-Y., & Wang, H.-L. (2014) · Toxicology Letters · doi:10.1016/j.toxlet.2013.11.025 · Cited by 85 · see citing works
Fuemmeler, B. F., Lee, C.-T., Soubry, A., Iversen, E. S., Huang, Z., Murtha, A. P., Schildkraut, J. M., Jirtle, R. L., Murphy, S. K., & Hoyo, C. (2016) · Genetics & Epigenetics · doi:10.4137/geg.s40538 · Cited by 85 · see citing works
Nieratschker, V., Massart, R., Gilles, M., Luoni, A., Suderman, M. J., Krumm, B., Meier, S., Witt, S. H., Nöthen, M. M., Suomi, S. J., et al. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.75 · Cited by 84 · see citing works
Effects of famine on placental size and efficiency
Roseboom, T. J., Painter, R. C., de Rooij, S. R., van Abeelen, A. F. M., Veenendaal, M. V. E., Osmond, C., & Barker, D. J. P. (2011) · Placenta · doi:10.1016/j.placenta.2011.03.001 · Cited by 84 · see citing works
Diaz, A., Eisenberg, N., Valiente, C., VanSchyndel, S. K., Spinrad, T. L., Berger, R. H., Hernández, M. M., Silva, K. M., & Southworth, J. (2015) · Journal of Research in Personality · doi:10.1016/j.jrp.2015.11.002 · Cited by 83 · see citing works
Montirosso, R., Provenzi, L., Fumagalli, M., Sirgiovanni, I., Giorda, R., Pozzoli, U., Beri, S., Menozzi, G., Tronick, E., Morandi, F., et al. (2016) · Child Development · doi:10.1111/cdev.12492 · Cited by 83 · see citing works
Acute and chronic effects of developmental iron deficiency on mRNA expression patterns in the brain
Clardy, S. L., Wang, X., Zhao, W., Liu, W., Chase, G. A., Beard, J. L., Felt, B. T., & Connor, J. R. (2006) · Springer eBooks · doi:10.1007/978-3-211-33328-0_19 · Cited by 82 · see citing works
Smit‐Rigter, L. A., Noorlander, C. W., von Oerthel, L., Chameau, P. J. P., Smidt, M. P., & van Hooft, J. A. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.09.015 · Cited by 81 · see citing works
Social learning of antipredator behaviour in a marsupial
Griffin, A. S., & Evans, C. S. (2003) · Animal Behaviour · doi:10.1006/anbe.2003.2207 · Cited by 81 · see citing works
Miyagawa, K., Tsuji, M., Fujimori, K., Saito, Y., & Takeda, H. (2011) · Neuroscience Research · doi:10.1016/j.neures.2011.02.002 · Cited by 81 · see citing works
Pawluski, J. L., Brain, U. M., Underhill, C., Hammond, G. L., & Oberlander, T. F. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.11.011 · Cited by 81 · see citing works
Origins of Effortful Control: Infant and Parent Contributions
Gartstein, M. A., Bridgett, D. J., Young, B. N., Panksepp, J., & Power, T. G. (2012) · Infancy · doi:10.1111/j.1532-7078.2012.00119.x · Cited by 80 · see citing works
Self-citationEmotional stress in pregnancy predicts human infant reactivity
Möhler, E., Parzer, P., Brunner, R., Wiebel, A., & Resch, F. (2006) · Early Human Development · doi:10.1016/j.earlhumdev.2006.02.010 · Cited by 80 · see citing works
Effect of Prenatal Exposure to Tobacco Smoke on Inhibitory Control
Holz, N. E., Boecker, R., Baumeister, S., Hohm, E., Zohsel, K., Buchmann, A. F., Blomeyer, D., Jennen-Steinmetz, C., Hohmann, S., Wolf, I., et al. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.343 · Cited by 78 · see citing works
Rodriguez, J. S., Rodríguez‐González, G. L., Reyes‐Castro, L. A., Ibáñez, C., Ramírez, A., Chavira, R., Larrea, F., Nathanielsz, P. W., & Zambrano, E. (2012) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2011.12.012 · Cited by 77 · see citing works
Endocrine disrupters: the new players able to affect the epigenome
Casati, L., Sendra, R., Sibilia, V., & Celotti, F. (2015) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2015.00037 · Cited by 76 · see citing works
O’Leary, C., Leonard, H., Bourke, J., et al. (2012) · Developmental Medicine & Child Neurology · doi:10.1111/dmcn.12029 · Cited by 76 · see citing works
Moshe Szyf, A., Tang, Y.-Y., Hemphill, S. A., & Musci, R. J. (2016) · Translational Behavioral Medicine · doi:10.1007/s13142-016-0387-7 · Cited by 76 · see citing works
Prenatal antidepressant exposure associated withCYP2E1DNA methylation change in neonates
Gurnot, C., Martin-Subero, I., Mah, S. M., Weikum, W., Goodman, S. J., Brain, U. M., Werker, J. F., Kobor, M. S., Esteller, M., Oberlander, T. F., et al. (2015) · Epigenetics · doi:10.1080/15592294.2015.1026031 · Cited by 74 · see citing works
Marjonen, H., Sierra, A., Nyman, A., Rogojin, V., Gröhn, O. H. J., Linden, A.-M., Hautaniemi, S., & Kaminen‐Ahola, N. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124931 · Cited by 73 · see citing works
Hamilton, D. A., Barto, D., Rodriguez, C. I., Magcalas, C. M., Fink, B. C., Rice, J. P., Bird, C. W., Davies, S., & Savage, D. D. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.04.029 · Cited by 73 · see citing works
Pérez‐Edgar, K. E., Schmidt, L. A., Henderson, H. A., Schulkin, J. A., & Fox, N. A. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.03.018 · Cited by 72 · see citing works
Temperament and common disruptive behavior problems in preschool
Martel, M. M., Gremillion, M. L., & Roberts, B. (2012) · Personality and Individual Differences · doi:10.1016/j.paid.2012.07.011 · Cited by 72 · see citing works
Alcohol modulates cytokine secretion and synthesis in human fetus: an in vivo and in vitro study
Ahluwalia, B. S., Wesley, B. D., Adeyiga, O., et al. (2000) · Alcohol · doi:10.1016/s0741-8329(00)00076-8 · Cited by 70 · see citing works
Reed, M. N., Paletz, E. M., & Newland, M. C. (2006) · NeuroToxicology · doi:10.1016/j.neuro.2006.03.022 · Cited by 69 · see citing works
Trezza, V., Campolongo, P., Manduca, A., Morena, M., Palmery, M., Vanderschuren, L. J. M. J., & Cuomo, V. (2012) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2012.00002 · Cited by 68 · see citing works
Temperament and the development of competence and motivation
Rothbart, M. K., & Hwang, J. (2005) · Cited by 67 · see citing works
Alvik, A., Torgersen, A. M., Aalen, O. O., & Lindemann, R. (2011) · Early Human Development · doi:10.1016/j.earlhumdev.2011.06.009 · Cited by 67 · see citing works
Behavioural outcomes of perinatal maternal fluoxetine treatment
McAllister, B. B., Kiryanova, V., & Dyck, R. H. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.09.024 · Cited by 66 · see citing works
Effects of iron deficiency on neonatal behavior at different stages of pregnancy
Hernández‐Martínez, C., Canals, J., Aranda, N., Ribot, B., Escribano, J., & Arija, V. (2011) · Early Human Development · doi:10.1016/j.earlhumdev.2010.12.006 · Cited by 66 · see citing works
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Cerritelli, F., Frasch, M. G., Antonelli, M. C., Viglione, C., Vecchi, S., Chiera, M., & Manzotti, A. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.721605 · Cited by 108 · see citing works
Provenzi, L., Grumi, S., Altieri, L., Bensi, G., Bertazzoli, E., Biasucci, G., Cavallini, A., Decembrino, L., Falcone, R., Freddi, A., et al. (2023) · Development and Psychopathology · doi:10.1017/s0954579421000766 · Cited by 99 · see citing works
A developmental cascade from prenatal stress to child internalizing and Externalizing problems
Hentges, R. F., Graham, S. A., Plamondon, A., Tough, S., & Madigan, S. (2019) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsz044 · Cited by 94 · see citing works
Cell-type-specific epigenetic effects of early life stress on the brain
Rahman, M. F., & McGowan, P. O. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02076-9 · Cited by 75 · see citing works
Wells, A. C., & Lotfipour, S. (2023) · Advances in Drug and Alcohol Research · doi:10.3389/adar.2023.11628 · Cited by 50 · see citing works
de Waal, N., Lodder, P., Nyklíček, I., Hulsbosch, L. P., van den Heuvel, M. I., van der Gucht, K., de Caluwé, E., Pop, V. J. M., & Boekhorst, M. G. B. M. (2024) · Early Human Development · doi:10.1016/j.earlhumdev.2024.106082 · Cited by 10 · see citing works
- Authors
- Gartstein, M. A., & Skinner, M. K.
- Affiliations
- Washington State University (US)
- Corresponding author
- Gartstein, Maria A.
- Skinner, Michael K.
- Venue
- Development and Psychopathology
- Publisher
- Cambridge University Press (CUP)
- Published
- 2017-12-12
- Volume
- 30
- Issue
- 4
- Pages
- 1269-1303
- ISSN
- 0954-5794 (ISSN-L)
- 1469-2198
- PMC
- PMC5997513
- OpenAlex
- W2773730878
- Cited by
- 161
- References
- 263
- Citations by year
- 2026: 9 · 2025: 14 · 2024: 9 · 2023: 10 · 2022: 19 · 2021: 28 · 2020: 54 · 2019: 12 · 2018: 6
- FWCI
- 3.20
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Development and Psychopathology (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- John Templeton Foundation
- National Institutes of Health
- National Institute of Environmental Health Sciences (R01ES012974)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- prenatal influences, infant temperament, environmental epigenetics, epigenetic programming, prenatal adversity, maternal stress, toxic exposure, maternal substance use, prenatal nutrition, attention deficit hyperactivity disorder, developmental origins of health and disease, social-emotional development, early brain development
- MeSH terms
- Attention Deficit Disorder with Hyperactivity, Child Development, Female, Humans, Infant, Learning, Pregnancy, Prenatal Exposure Delayed Effects, Temperament, Epigenesis, Genetic
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