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Health benefits of physical activity: the evidence
Open accessAbstract
The primary purpose of this narrative review was to evaluate the current literature and to provide further insight into the role physical inactivity plays in the development of chronic disease and premature death. We confirm that there is irrefutable evidence of the effectiveness of regular physical activity in the primary and secondary prevention of several chronic diseases (e.g., cardiovascular disease, diabetes, cancer, hypertension, obesity, depression and osteoporosis) and premature death. We also reveal that the current Health Canada physical activity guidelines are sufficient to elicit health benefits, especially in previously sedentary people. There appears to be a linear relation between physical activity and health status, such that a further increase in physical activity and fitness will lead to additional improvements in health status.
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“It is well documented that physical activity has considerable beneficial ef fects on overall health, protecting against individual physical morbid ities and improving psychological well-being by reducing stress, anxiety, and depression (Warburton et al., 2006).”
From Psychosocial risk and protective factors associated with burnout in police officers: A systematic review (2023) · cites this paper as Warburton et al., 2006
In the citing paper
“Thus, it is unsurprising that physical fitness, which ultimately is related to total PA levels, is generally regarded as the single best predictor of all-cause mortality, independent of disease state.12”
From Reduced physical activity in young and older adults: Metabolic and musculoskeletal implications (2019) · cites this paper as [12]
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“Regular physical activity and/or exercise that is tailored to improve cardiorespiratory fitness, such as walking, dancing, or cycling, has significant health benefits such as reducing the risk of cardiovascular disease, diabetes, and obesity (28).”
From Exercise Intervention in PTSD: A Narrative Review and Rationale for Implementation (2019) · cites this paper as [28]
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“Aerobic exercise is a low-cost, widely accessible activity known to provide multiple health benefits, including cardiovascular health and musculoskeletal health, as well as reduced rates of co-morbidity and mortality”
From Exercise Intervention in PTSD: A Narrative Review and Rationale for Implementation (2019) · cites this paper as [28]
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Cites
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011
Tuomilehto, J., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Laakso, M., Louheranta, A., Rastas, M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105033441801 · Cited by 10,873
Exercise capacity and mortality among men referred for exercise testing
Myers, J., Prakash, M., Froelicher, V., Do, D., Partington, S., & Atwood, J. E. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa011858 · Cited by 4,114
Healthy People 2000: National Health Promotion and Disease Prevention Objectives.
Heidel, R. E. (1991) · Population and Development Review · doi:10.2307/1971966 · Cited by 3,162
Physical Activity, All-Cause Mortality, and Longevity of College Alumni
Paffenbarger, R. S., Hyde, R., Wing, A. L., & Hsieh, C.-C. (1986) · New England Journal of Medicine · doi:10.1056/nejm198603063141003 · Cited by 2,742
Physical Fitness and All-Cause Mortality: A Prospective Study of Healthy Men and Women
Blair, S. N. (1989) · JAMA · doi:10.1001/jama.1989.03430170057028 · Cited by 2,658
Taylor, R. S., Brown, A., Ebrahim, S., Jolliffe, J., Noorani, H., Rees, K., Skidmore, B., Stone, J. A., Thompson, D. R., & Oldridge, N. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.01.009 · Cited by 2,239
Tinetti, M. E., Baker, D. I., McAvay, G., Claus, E. B., Garrett, P., Gottschalk, M., Koch, M. L., Trainor, K. M., & Horwitz, R. I. (1994) · New England Journal of Medicine · doi:10.1056/nejm199409293311301 · Cited by 2,160
Paffenbarger, R. S., Hyde, R. T., Wing, A. L., Lee, I.-M., Jung, D. L., & Kampert, J. B. (1993) · New England Journal of Medicine · doi:10.1056/nejm199302253280804 · Cited by 1,972
Boulé, N. G., Haddad, E., Kenny, G. P., Wells, G. A., & Sigal, R. J. (2001) · JAMA · doi:10.1001/jama.286.10.1218 · Cited by 1,889
Research works printed but not linked: 4
- [72]72. Courneya KS, Jones LW, Fairey AS, et al. Physical activity in cancer survivors: impli- cations for recurrence and mortality. Cancer Therapy 2004;2:1-12.
- [112]112. Brown JP, Josse RG. 2002 clinical practice guidelines for the diagnosis and man- agement of osteoporosis in Canada [published errata in CMAJ 2003;168(4):400, 2003;168(6):676 and 2003;168(5):544]. CMAJ 2002;167(10 Suppl):S1-34.
- [137]137. Warburton DER, Gledhill N, Jamnik V, et al. Induced hypervolemia, cardiac func- tion, VO 2max and performance of elite cyclists. Med Sci Sports Exerc 1999;31:800-8.
- [145]145. Ferreira I, Twisk JW, Stehouwer CD, et al. Longitudinal changes in VO 2max : associa- tions with carotid IMT and arterial stiffness. Med Sci Sports Exerc 2003;35:1670-8.
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Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.190811 · Cited by 2,068
Migueles, J. H., Cadenas‐Sánchez, C., Ekelund, U., Nyström, C. D., Mora-González, J., Löf, M., Labayen, I., Ruiz, J. R., & Ortega, F. B. (2017) · Sports Medicine · doi:10.1007/s40279-017-0716-0 · Cited by 2,022
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Wen, C. P., Wai, J. P. M., Tsai, M. K., Yang, Y. C., Cheng, T. Y. D., Lee, M.-C., Chan, H. T., Tsao, C. K., Tsai, S. P., & Wu, X. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60749-6 · Cited by 1,908
Twohig-Bennett, C., & Jones, A. (2018) · Environmental Research · doi:10.1016/j.envres.2018.06.030 · Cited by 1,766
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Hertzog, C., Kramer, A. F., Wilson, R. S., & Lindenberger, U. (2008) · Psychological Science in the Public Interest · doi:10.1111/j.1539-6053.2009.01034.x · Cited by 1,495
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Anderson, E., & Durstine, J. L. (2019) · Sports Medicine and Health Science · doi:10.1016/j.smhs.2019.08.006 · Cited by 1,162
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McCormack, G. R., Rock, M. J., Toohey, A. M., & Hignell, D. (2010) · Health & Place · doi:10.1016/j.healthplace.2010.03.003 · Cited by 1,094
Nocon, M., Hiemann, T., Müller-Riemenschneider, F., Thalau, F., Roll, S., & Willich, S. N. (2008) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e3282f55e09 · Cited by 1,080
Mikkelsen, K., Stojanovska, L., Polenakovic, M., Bosevski, M., & Apostolopoulos, V. (2017) · Maturitas · doi:10.1016/j.maturitas.2017.09.003 · Cited by 1,072
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Owen, N. G., Sugiyama, T., Eakin, E., Gardiner, P. A., Tremblay, M. S., & Sallis, J. F. (2011) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2011.05.013 · Cited by 944
The impact of physical activity on psychological health during Covid-19 pandemic in Italy
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Warburton, D. E., Charlesworth, S., Ivey, A., Nettlefold, L., & Bredin, S. S. (2010) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-7-39 · Cited by 902
Self-citationKarlsson, J., Taft, C., Rydén, A., Sjöström, L., & Sullivan, M. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803573 · Cited by 887
Loef, M., & Walach, H. (2012) · Preventive Medicine · doi:10.1016/j.ypmed.2012.06.017 · Cited by 883
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Cairney, J., Dudley, D. A., KWAN, M. Y. W., Bulten, R., & Kriellaars, D. J. (2019) · Sports Medicine · doi:10.1007/s40279-019-01063-3 · Cited by 879
Rhodes, R. E., & Kates, A. (2015) · Annals of Behavioral Medicine · doi:10.1007/s12160-015-9704-5 · Cited by 852
Gomez-Cabrera, M.-C., Domenech, E., Romagnoli, M., Arduini, A., Borras, C., Pallardo, F. V., Sastre, J., & Viña, J. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.1.142 · Cited by 844
Samitz, G., Egger, M., & Zwahlen, M. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr112 · Cited by 836
Dunstan, D. W., Barr, E. L. M., Healy, G. N., Salmon, J., Shaw, J. E., Balkau, B., Magliano, D. J., Cameron, A. J., Zimmet, P. Z., & Owen, N. (2010) · Circulation · doi:10.1161/circulationaha.109.894824 · Cited by 825
Position statement on physical activity and exercise intensity terminology.
Norton, K., Norton, L., & Sadgrove, D. (2010) · Journal of Science and Medicine in Sport · doi:10.1016/j.jsams.2009.09.008 · Cited by 804
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Quach, A., Levine, M. E., Tanaka, T., Lu, A. T., Chen, B. H., Ferrucci, L., Ritz, B., Bandinelli, S., Neuhouser, M. L., Beasley, J. M., et al. (2017) · Aging · doi:10.18632/aging.101168 · Cited by 801
Ristow, M., & Zarse, K. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.03.014 · Cited by 789
Anderson, T. J., Grégoire, J. C., Hegele, R. A., Couture, P., Mancini, G. B. J., McPherson, R., Francis, G. A., Poirier, P., Lau, D. C. W., Grover, S. A., et al. (2013) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2012.11.032 · Cited by 780
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Hidaka, B. H. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.12.036 · Cited by 769
Curriculum, K. (2006) · Cited by 768
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Schulz, R., Beach, S. R., Czaja, S. J., Martire, L. M., & Monin, J. K. (2020) · Annual Review of Psychology · doi:10.1146/annurev-psych-010419-050754 · Cited by 754
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Buchman, A. S., Boyle, P. A., Yu, L., Shah, R. C., Wilson, R. S., & Bennett, D. A. (2012) · Neurology · doi:10.1212/wnl.0b013e3182535d35 · Cited by 730
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Edwards, L. C., Bryant, A. S., Keegan, R. J., Morgan, K., & Jones, A. M. (2016) · Sports Medicine · doi:10.1007/s40279-016-0560-7 · Cited by 730
Mishra, S. I., Scherer, R. W., Snyder, C. F., Geigle, P. M., Berlanstein, D. R., & Topaloglu, Ö. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008465.pub2 · Cited by 729
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Winters, S., Martin, C., Murphy, D. E., & Shokar, N. K. (2017) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2017.07.002 · Cited by 721
Grant, P., Ryan, C. G., Tigbe, W. W., & Granat, M. H. (2006) · British Journal of Sports Medicine · doi:10.1136/bjsm.2006.030262 · Cited by 711
Little, J. P., Safdar, A., Wilkin, G. P., Tarnopolsky, M. A., & Gibala, M. J. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2009.181743 · Cited by 708
Ruegsegger, G. N., & Booth, F. W. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a029694 · Cited by 690
Brickwood, K.-J., Watson, G., O'Brien, J., & Williams, A. D. (2019) · JMIR mHealth and uHealth · doi:10.2196/11819 · Cited by 689
Lauersen, J. B., Bertelsen, D. M., & Andersen, L. B. (2013) · British Journal of Sports Medicine · doi:10.1136/bjsports-2013-092538 · Cited by 688
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Self-citationVerburgh, L., Königs, M., Scherder, E. J. A., & Oosterlaan, J. (2014) · British Journal of Sports Medicine · doi:10.1136/bjsports-2012-091441 · Cited by 617
Lumba‐Brown, A., Yeates, K. O., Sarmiento, K., Breiding, M. J., Haegerich, T. M., Gioia, G. A., Turner, M., Benzel, E. C., Suskauer, S. J., Giza, C. C., et al. (2018) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2018.2853 · Cited by 603
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Romero, C., Rodríguez‐Almagro, J., Zafra, M. D. O., Parra-Fernández, M. L., Prado-Laguna, M. D. C., & Hernández‐Martínez, A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186567 · Cited by 587
Health benefits of physical activity in older patients: a review
Vogel, T., Bréchat, P.-H., Leprêtre, P., Kaltenbach, G., Berthel, M., & Lonsdorfer, J. (2009) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2008.01957.x · Cited by 575
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Cherkas, L. F. (2008) · Archives of Internal Medicine · doi:10.1001/archinternmed.2007.39 · Cited by 572
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Slater, A., & Tiggemann, M. (2010) · Journal of Adolescence · doi:10.1016/j.adolescence.2010.06.007 · Cited by 551
Stout, K., Daniels, C. J., Aboulhosn, J., Bozkurt, B., Broberg, C. S., Colman, J. M., Crumb, S. R., Dearani, J. A., Fuller, S., Gurvitz, M. Z., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000602 · Cited by 548
The Antidepressive Effects of Exercise: A Meta-Analysis of Randomized Trials
Rethorst, C. D., Wipfli, B. M., & Landers, D. M. (2009) · Sports Medicine · doi:10.2165/00007256-200939060-00004 · Cited by 541
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Ristow, M., & Schmeisser, K. (2014) · Dose-Response · doi:10.2203/dose-response.13-035.ristow · Cited by 534
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Clark, A. M., DesMeules, M., Luo, W., Duncan, A. S., & Wielgosz, A. (2009) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2009.163 · Cited by 533
Beck, L. F., Dellinger, A. M., & O’Neil, M. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwm064 · Cited by 532
Rhodes, R. E., Mark, R. S., & Temmel, C. S. D. (2012) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2011.10.020 · Cited by 529
Deliens, T., Deforche, B. I., Bourdeaudhuij, I. D., & Clarys, P. (2015) · BMC Public Health · doi:10.1186/s12889-015-1553-4 · Cited by 525
Mailing, L. J., Allen, J. M., Buford, T. W., Fields, C. J., & Woods, J. A. (2019) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000183 · Cited by 521
Tabacof, L., Tosto-Mancuso, J., Wood, J., Cortes, M., Kontorovich, A., McCarthy, D., Rizk, D., Rozanski, G., Breyman, E., Nasr, L., et al. (2021) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000001910 · Cited by 517
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Contrepois, K., Wu, S., Moneghetti, K. J., Hornburg, D., Ahadi, S., Tsai, M.-S., Metwally, A. A., Wei, E., Lee-McMullen, B., Quijada, J. V., et al. (2020) · Cell · doi:10.1016/j.cell.2020.04.043 · Cited by 502
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Romeo, A., Edney, S., Plotnikoff, R., Curtis, R., Ryan, J., Sanders, I., Crozier, A., & Maher, C. (2019) · Journal of Medical Internet Research · doi:10.2196/12053 · Cited by 487
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Smith, A. D., Crippa, A., Woodcock, J., & Brage, S. (2016) · Diabetologia · doi:10.1007/s00125-016-4079-0 · Cited by 430
Zarse, K., Schmeisser, S., Groth, M., Priebe, S., Beuster, G., Kuhlow, D., Guthke, R., Platzer, M., Kahn, C. R., & Ristow, M. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.02.013 · Cited by 430
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Metadata
- Authors
- Warburton, D. E. R.
- Affiliations
- University of British Columbia (CA)
- Corresponding author
- Warburton, D. E.R.
- ORCID
- Warburton, D. E.R.
- Venue
- Canadian Medical Association Journal
- Publisher
- CMA Joule Inc.
- Published
- 2006-03-14
- Volume
- 174
- Issue
- 6
- Pages
- 801-809
- ISSN
- 0820-3946 (ISSN-L)
- 1488-2329
- PMC
- PMC1402378
- OpenAlex
- W2128621051
- Cited by
- 8,007
- References
- 181
- Citations by year
- 2026: 275 · 2025: 437 · 2024: 486 · 2023: 479 · 2022: 482 · 2021: 623 · 2020: 539 · 2019: 566 · 2018: 575 · 2017: 487 · 2016: 510 · 2015: 473 · 2014: 414 · 2013: 411 · 2012: 319
- FWCI
- 15.21
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Canadian Medical Association Journal (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Michael Smith Health Research BC
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Social Sciences › Life-span and Life-course Studies › Recreational Sport and Physical Activity
- Keywords
- physical activity, physical inactivity, chronic disease prevention, premature mortality, cardiovascular disease, diabetes mellitus, cancer, hypertension, obesity, depression, osteoporosis, physical activity guidelines, sedentary individuals, dose-response relationship, health benefits
- MeSH terms
- Cardiovascular Diseases, Chronic Disease, Diabetes Mellitus, Health Status, Humans, Life Expectancy, Neoplasms, Physical Fitness, Health Behavior, Exercise
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