The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Theoretically, combining probiotics with omega-3 fatty acids may offer a promising nutritional strategy to counteract metabolic challenges associated with aging via the gut microbiota, especially relevant for older people that suffer from anabolic resistance, systemic inflammation, and mood disorders (through the gut–brain axis) [279,294,295].”
From Nutrition for Older Athletes: Focus on Sex-Differences (2021) · cites this paper as [294]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
Kim, D., Pertea, G., Trapnell, C., Pimentel, H., Kelley, R., & Salzberg, S. L. (2013) · Genome Biology · doi:10.1186/gb-2013-14-4-r36 · Cited by 12,668
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Franceschi, C., & Campisi, J. (2014) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glu057 · Cited by 3,891
Oh, D. Y., Talukdar, S., Bae, E. J., Imamura, T., Morinaga, H., Fan, W., Li, P., Lu, W. J., Watkins, S. M., & Olefsky, J. M. (2010) · Cell · doi:10.1016/j.cell.2010.07.041 · Cited by 2,428
Human aging, muscle mass, and fiber type composition.
Evans, W. J., & Lexell, J. (1995) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/50a.special_issue.11 · Cited by 1,308
Kregel, K. C., & Zhang, H. J. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00327.2006 · Cited by 883
Kumar, V., Selby, A., Rankin, D., Patel, R., Atherton, P., Hildebrandt, W., Williams, J., Smith, K., Seynnes, O., Hiscock, N., et al. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2008.164483 · Cited by 740 · cited 2×
“There is convincing evidence that anabolic responses to nutrition or exercise stimuli are blunted with aging [24-26].”
BackgroundOxidative capacity and ageing in human muscle
Conley, K. E., Jubrias, S. A., & Esselman, P. C. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.t01-1-00203.x · Cited by 651 · cited 1×
“Sarcopenia has multifactorial origins, and its negative influence on healthspan is compounded by other related hallmarks of aging, which include reduced whole-body peak oxygen uptake (VO2 peak) [4], neurodegenerative changes, increased adiposity [5, 6], decreased regenerative potential of the muscle stem cell niche [7…”
BackgroundEndurance Exercise as a Countermeasure for Aging
Lanza, I. R., Short, D. K., Short, K. R., Raghavakaimal, S., Basu, R., Joyner, M. J., McConnell, J. P., & Nair, K. S. (2008) · Diabetes · doi:10.2337/db08-0349 · Cited by 582
Self-citationAmino acid ingestion improves muscle protein synthesis in the young and elderly
Paddon-Jones, D., Sheffield-Moore, M., Zhang, X.-J., Volpi, E., Wolf, S. E., Aarsland, A., Ferrando, A. A., & Wolfe, R. R. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00368.2003 · Cited by 467 · cited 1×
“The precedent literature is mixed concerning the effects of aging on muscle protein synthesis under postabsorptive conditions with some investigators reporting reductions in FSR with age [45, 46], while others do not [47, 48].”
BackgroundResistance exercise decreases skeletal muscle tumor necrosis factor α in frail elderly humans
GREIWE, J. S., CHENG, B., RUBIN, D. C., YARASHESKI, K. E., & SEMENKOVICH, C. F. (2001) · The FASEB Journal · doi:10.1096/fj.00-0274com · Cited by 454
Collerton, J., Martin-Ruiz, C., Davies, K., Hilkens, C. M., Isaacs, J., Kolenda, C., Parker, C., Dunn, M., Catt, M., Jagger, C., et al. (2012) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2012.05.005 · Cited by 420
Smith, G. I., Atherton, P., Reeds, D. N., Mohammed, B. S., Rankin, D., Rennie, M. J., & Mittendorfer, B. (2011) · Clinical Science · doi:10.1042/cs20100597 · Cited by 372
Aging impairs contraction-induced human skeletal muscle mtorc1 signaling and protein synthesis
Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Dhanani, S., Volpi, E., & Rasmussen, B. B. (2011) · Skeletal Muscle · doi:10.1186/2044-5040-1-11 · Cited by 351
Hasten, D. L., Pak-Loduca, J., Obert, K. A., & Yarasheski, K. E. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.278.4.e620 · Cited by 294
TNF-α impairs heart and skeletal muscle protein synthesis by altering translation initiation
Lang, C. H., Frost, R. A., Nairn, A. C., MacLean, D. A., & Vary, T. C. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00366.2001 · Cited by 265
Mayhew, D. L., Kim, J.-S., Cross, J. M., Ferrando, A. A., & Bamman, M. M. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.91234.2008 · Cited by 215
Large energetic adaptations of elderly muscle to resistance and endurance training
Jubrias, S. A., Esselman, P. C., Price, L. B., Cress, M. E., & Conley, K. E. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.5.1663 · Cited by 213
Da Boit, M., Sibson, R., Sivasubramaniam, S., Meakin, J. R., Greig, C. A., Aspden, R. M., Thies, F., Jeromson, S., Hamilton, D. L., Speakman, J. R., et al. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.140780 · Cited by 185
Browning, L. M., Krebs, J. D., Moore, C. S., Mishra, G. D., O’Connell, M. A., & Jebb, S. A. (2007) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2006.00576.x · Cited by 162
McGlory, C., Wardle, S. L., Macnaughton, L. S., Witard, O. C., Scott, F., Dick, J., Bell, J. G., Phillips, S. M., Galloway, S. D. R., Hamilton, D. L., et al. (2016) · Physiological Reports · doi:10.14814/phy2.12715 · Cited by 103
Effect of dietary n-3 PUFA supplementation on the muscle transcriptome in older adults
Yoshino, J., Smith, G. I., Kelly, S. C., Julliand, S., Reeds, D. N., & Mittendorfer, B. (2016) · Physiological Reports · doi:10.14814/phy2.12785 · Cited by 76
Lalia, A. Z., Johnson, M. L., Jensen, M. D., Hames, K. C., Port, J. D., & Lanza, I. R. (2015) · Diabetes Care · doi:10.2337/dc14-3101 · Cited by 73
Self-citationJohnson, M. L., Lalia, A. Z., Dasari, S., Pallauf, M., Fitch, M., Hellerstein, M. K., & Lanza, I. R. (2015) · Aging Cell · doi:10.1111/acel.12352 · Cited by 66
Self-citationRobinson, M. M., Soop, M., Sohn, T. S., Morse, D. M., Schimke, J. M., Klaus, K. A., & Nair, K. S. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-2736 · Cited by 59
Self-citation
Research works printed but not linked: 44
- Evans, 1991, A cross-sectional study of muscle strength and mass in 45- to 78-yr-old men and women., J Appl Physiol (1985), 7, 644
- Wallace, 1995, Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability., N Engl J Med, 33, 556, 10.1056/NEJM199503023320902 · DOI · Paper page
- Nair, 2010, Mitochondrial DNA alterations and reduced mitochondrial function in aging., Mech Ageing Dev, 13, 451, 10.1016/j.mad.2010.03.007 · DOI
- Cassidy, 2014, Dietary fat and fatty acid profile are associated with indices of skeletal muscle mass in women aged 18-79 years., J Nutr, 14, 327, 10.3945/jn.113.185256 · DOI
- Lanza, 2016, Predictors of whole-body insulin sensitivity across ages and adiposity in adult humans., J Clin Endocrinol Metab, 10, 626, 10.1210/jc.2015-2892 · DOI
- Mouly, 2002, Regenerative potential of human skeletal muscle during aging., Aging Cell, 1, 132, 10.1046/j.1474-9728.2002.00017.x · DOI · Paper page
- Rando, 2005, Aging, stem cells and tissue regeneration: lessons from muscle., Cell Cycle, 4, 407, 10.4161/cc.4.3.1518 · DOI · Paper page
- Shulman, 2003, Mitochondrial dysfunction in the elderly: possible role in insulin resistance., Science, 30, 1140, 10.1126/science.1082889 · DOI · Paper page
- Nair, 2005, Decline in skeletal muscle mitochondrial function with aging in humans., Proc Natl Acad Sci USA, 10, 5618, 10.1073/pnas.0501559102 · DOI · Paper page
- Holloszy, 1984, Effects of endurance training on glucose tolerance and plasma lipid levels in older men and women., JAMA, 25, 645, 10.1001/jama.1984.03350050033022 · DOI · Paper page
- van Loon, 2013, Elderly men and women benefit equally from prolonged resistance-type exercise training., J Gerontol A Biol Sci Med Sci, 6, 769, 10.1093/gerona/gls241 · DOI · Paper page
- Nair, 2001, Age effect on transcript levels and synthesis rate of muscle MHC and response to resistance exercise., Am J Physiol Endocrinol Metab, 28, E203
- Goodpaster, 2006, Effects of exercise on mitochondrial content and function in aging human skeletal muscle., J Gerontol A Biol Sci Med Sci, 6, 534, 10.1093/gerona/61.6.534 · DOI · Paper page
- van Loon, 2009, Skeletal muscle hypertrophy following resistance training is accompanied by a fiber type-specific increase in satellite cell content in elderly men., J Gerontol A Biol Sci Med Sci, 6, 332, 10.1093/gerona/gln050 · DOI · Paper page
- Holloszy, 1992, Skeletal muscle adaptations to endurance training in 60- to 70-yr-old men and women., J Appl Physiol (1985), 7, 1780
- Nair, 2003, Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity., Diabetes, 5, 1888, 10.2337/diabetes.52.8.1888 · DOI · Paper page
- Bamman, 2008, Modulation of the dystrophin-associated protein complex in response to resistance training in young and older men., J Appl Physiol (1985), 10, 1476, 10.1152/japplphysiol.00708.2007 · DOI
- Bamman, 2006, Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults., J Appl Physiol (1985), 10, 531, 10.1152/japplphysiol.01474.2005 · DOI · Paper page
- Rennie, 2009, Anabolic resistance: the effects of aging, sexual dimorphism, and immobilization on human muscle protein turnover., Appl Physiol Nutr Metab, 3, 377, 10.1139/H09-012 · DOI
- Health, 2009, Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength., J Gerontol A Biol Sci Med Sci, 6, 1183, 10.1093/gerona/glp097 · DOI · Paper page
- Previs, 2005, Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activation., Am J Physiol Endocrinol Metab, 28, E883, 10.1152/ajpendo.00353.2004 · DOI
- Dardevet, 2009, Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats., J Physiol, 58, 5483, 10.1113/jphysiol.2009.178319 · DOI
- Mittendorfer, 2011, Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial., Am J Clin Nutr, 9, 402, 10.3945/ajcn.110.005611 · DOI · Paper page
- Hollon, 2011, Influence of acetaminophen and ibuprofen on skeletal muscle adaptations to resistance exercise in older adults., Am J Physiol Regul Integr Comp Physiol, 30, R655, 10.1152/ajpregu.00611.2010 · DOI
- Fernandes, 2012, Fish-oil supplementation enhances the effects of strength training in elderly women., Am J Clin Nutr, 9, 428, 10.3945/ajcn.111.021915 · DOI · Paper page
- Valcárcel-Ares, 2013, Mitochondrial dysfunction and the inflammatory response., Mitochondrion, 1, 106, 10.1016/j.mito.2013.01.003 · DOI · Paper page
- Kern, 2013, Omega-3 fatty acids reduce adipose tissue macrophages in human subjects with insulin resistance., Diabetes, 6, 1709, 10.2337/db12-1042 · DOI
- Zabielski, 2013, Influence of fish oil on skeletal muscle mitochondrial energetics and lipid metabolites during high-fat diet., Am J Physiol Endocrinol Metab, 30, E1391, 10.1152/ajpendo.00584.2012 · DOI · Paper page
- Nair, 1996, Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle., Proc Natl Acad Sci USA, 9, 15364, 10.1073/pnas.93.26.15364 · DOI · Paper page
- Bier, 1993, Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women., Am J Physiol, 26, E210
- Wolfe, 2001, Basal muscle amino acid kinetics and protein synthesis in healthy young and older men., JAMA, 28, 1206, 10.1001/jama.286.10.1206 · DOI · Paper page
- Holloway, 2014, Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle., J Physiol, 59, 1341, 10.1113/jphysiol.2013.267336 · DOI · Paper page
- Visioli, 2008, Polyunsaturated fatty acids as antioxidants., Pharmacol Res, 5, 451, 10.1016/j.phrs.2008.05.002 · DOI · Paper page
- Goto, 2008, Caloric restriction optimizes the proteasome pathway with aging in rat plantaris muscle: implications for sarcopenia., Am J Physiol Regul Integr Comp Physiol, 29, R1231, 10.1152/ajpregu.90478.2008 · DOI
- Jakaitis, 2012, Chronic caloric restriction preserves mitochondrial function in senescence without increasing mitochondrial biogenesis., Cell Metab, 1, 777, 10.1016/j.cmet.2012.11.003 · DOI · Paper page
- Attardi, 1999, Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication., Science, 28, 774, 10.1126/science.286.5440.774 · DOI · Paper page
- Fearon, 2000, Effect of oral eicosapentaenoic acid on weight loss in patients with pancreatic cancer., Nutr Cancer, 3, 177, 10.1207/S15327914NC3602_6 · DOI · Paper page
- Ristic, 2007, Effects of N-3 PUFAs supplementation on insulin resistance and inflammatory biomarkers in hemodialysis patients., Ren Fail, 2, 321, 10.1080/08860220601184092 · DOI
- Nair, 2009, Functional assessment of isolated mitochondria in vitro., Methods Enzymol, 45, 349, 10.1016/S0076-6879(09)05020-4 · DOI
- Nair, 2013, Comparison of different mass spectrometry techniques in the measurement of L-[ring-(13)C6]phenylalanine incorporation into mixed muscle proteins., J Mass Spectrom, 4, 269, 10.1002/jms.3120 · DOI
- Schmittgen, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method., Methods, 2, 402, 10.1006/meth.2001.1262 · DOI · Paper page
- Thompson, 2014, MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing., BMC Bioinformatics, 1, 224, 10.1186/1471-2105-15-224 · DOI · Paper page
- Smyth, 2010, edgeR: a Bioconductor package for differential expression analysis of digital gene expression data., Bioinformatics, 2, 139, 10.1093/bioinformatics/btp616 · DOI · Paper page
- Jensen, 2010, Rapid measurement of plasma free fatty acid concentration and isotopic enrichment using LC/MS., J Lipid Res, 5, 2761, 10.1194/jlr.M008011 · DOI
Cited by
Nutrition and Sarcopenia—What Do We Know?
Ganapathy, A., & Nieves, J. W. (2020) · Nutrients · doi:10.3390/nu12061755 · Cited by 355
Huang, Y., Zhu, X., Chen, K., Lang, H., Zhang, Y., Hou, P., Ran, L., Zhou, M., Zheng, J., Yi, L., et al. (2019) · Aging · doi:10.18632/aging.101910 · Cited by 167
Cruz-Jentoft, A. J., Dawson Hughes, B., Scott, D., Sanders, K. M., & Rizzoli, R. (2020) · Maturitas · doi:10.1016/j.maturitas.2019.11.007 · Cited by 144
Huang, Y.-H., Chiu, W.-C., Hsu, Y.-P., Lo, Y.-L., & Wang, Y.-H. (2020) · Nutrients · doi:10.3390/nu12123739 · Cited by 142
Potential Roles of n-3 PUFAs during Skeletal Muscle Growth and Regeneration
Tachtsis, B., Camera, D., & Lacham-Kaplan, O. (2018) · Nutrients · doi:10.3390/nu10030309 · Cited by 104
Metadata
- Authors
- Lalia, A. Z., Dasari, S., Robinson, M. M., Abid, H., Morse, D. M., Klaus, K. A., & Lanza, I. R.
- Affiliations
- Division of Endocrinology and Metabolism, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
- Venue
- Aging
- Publisher
- Impact Journals, LLC
- Published
- 2017-04-05
- Volume
- 9
- Issue
- 4
- Pages
- 1096-1129
- ISSN
- 1945-4589
- Cited by
- 140
- References
- 25
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.