Cited by 343Genetic Associations and EpidemiologyAssisted Reproductive Technology and Twin PregnancyAdvanced Causal Inference Techniques

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Critical Need for Family-Based, Quasi-Experimental Designs in Integrating Genetic and Social Science Research

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D’Onofrio, Brian M., Lahey, Benjamin B., Turkheimer, Eric, Lichtenstein, Paul·2013·American Journal of Public Health

DOI 10.2105/ajph.2013.301252PMC PMC3778076

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Abstract

Researchers have identified environmental risks that predict subsequent psychological and medical problems. Based on these correlational findings, researchers have developed and tested complex developmental models and have examined biological moderating factors (e.g., gene-environment interactions). In this context, we stress the critical need for researchers to use family-based, quasi-experimental designs when trying to integrate genetic and social science research involving environmental variables because these designs rigorously examine causal inferences by testing competing hypotheses. We argue that sibling comparison, offspring of twins or siblings, in vitro fertilization designs, and other genetically informed approaches play a unique role in bridging gaps between basic biological and social science research. We use studies on maternal smoking during pregnancy to exemplify these principles.

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Untitled work
(2002) · Cited by 13,211
Methodology for Genetic Studies of Twins and Families
Neale, M. C., & Cardon, L. R. (1992) · doi:10.1007/978-94-015-8018-2 · Cited by 4,005
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
Gluckman, P. D., Hanson, M. A., Cooper, C., & Thornburg, K. L. (2008) · New England Journal of Medicine · doi:10.1056/nejmra0708473 · Cited by 3,898
Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).
Spielman, R. S., McGinnis, R. E., & Ewens, W. J. (1993) · PubMed · Cited by 3,679
How People Make Their Own Environments: A Theory of Genotype Environment Effects
Scarr, S., & McCartney, K. (1983) · Child Development · doi:10.1111/j.1467-8624.1983.tb03884.x · Cited by 2,895
Untitled work
(2009) · Cited by 2,013
Genotype-environment interaction and correlation in the analysis of human behavior.
Plomin, R., DeFries, J. C., & Loehlin, J. C. (1977) · Psychological Bulletin · doi:10.1037/0033-2909.84.2.309 · Cited by 1,685
Gene–environment interactions in psychiatry: joining forces with neuroscience
Caspi, A., & Moffitt, T. E. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1925 · Cited by 1,300
The science of prevention. A conceptual framework and some directions for a national research program
Coie, J. D., Watt, N. F., West, S. G., Hawkins, J. D., Asarnow, J. R., Markman, H. J., Ramey, S. L., Shure, M. B., & Long, B. (1993) · American Psychologist · doi:10.1037/0003-066x.48.10.1013 · Cited by 1,253
The science of prevention: A conceptual framework and some directions for a national research program.
Coie, J. D., Watt, N. F., West, S. G., Hawkins, J. D., Asarnow, J. R., Markman, H. J., Ramey, S. L., Shure, M. B., & Long, B. (1993) · American Psychologist · doi:10.1037//0003-066x.48.10.1013 · Cited by 1,247
Developmental cascades: Linking academic achievement and externalizing and internalizing symptoms over 20 years
Masten, A. S., Roisman, G. I., Long, J. D., Burt, K. B., Obradović, J., Riley, J. R., Boelcke-Stennes, K., & Tellegen, A. (2005) · Developmental Psychology · doi:10.1037/0012-1649.41.5.733 · Cited by 1,152
The epidemiology of smoking during pregnancy: smoking prevalence, maternal characteristics, and pregnancy outcomes
Cnattingius, S. (2004) · Nicotine & Tobacco Research · doi:10.1080/14622200410001669187 · Cited by 1,126
Gene-environment interplay and psychopathology: multiple varieties but real effects
Rutter, M., Moffitt, T. E., & Caspi, A. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2005.01557.x · Cited by 1,058
A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry
Duncan, L. E., & Keller, M. C. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.11020191 · Cited by 1,032
Early Life Programming and Neurodevelopmental Disorders
Bale, T. L., Baram, T. Z., Brown, A. S., Goldstein, J. M., Insel, T. R., McCarthy, M. M., Nemeroff, C. B., Reyes, T. M., Simerly, R. B., Susser, E. S., et al. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.05.028 · Cited by 961
Epidemiology Faces Its Limits: The search for subtle links between diet, lifestyle, or environmental factors and disease is an unending source of fear—but often yields little certainty
Taubes, G. (1995) · Science · doi:10.1126/science.7618077 · Cited by 841
Strategy for Investigating Interactions Between Measured Genes and Measured Environments
Moffitt, T. E., Caspi, A., & Rutter, M. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.5.473 · Cited by 784
Translational and Clinical Science — Time for a New Vision
Zerhouni, E. A. (2005) · New England Journal of Medicine · doi:10.1056/nejmsb053723 · Cited by 729
Genetic influences on measures of the environment: a systematic review
KENDLER, K. S., & BAKER, J. H. (2007) · Psychological Medicine · doi:10.1017/s0033291706009524 · Cited by 725
Genes and behavior: Nature-nurture interplay explained
Rose, R. J., & Rutter, M. L. (2007) · European Psychologist · doi:10.1027/1016-9040.12.3.240 · Cited by 654
Gene–environment correlations: a review of the evidence and implications for prevention of mental illness
Jaffee, S. R., & Price, T. S. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001950 · Cited by 596
Behavioral and Neural Consequences of Prenatal Exposure to Nicotine
ERNST, M., MOOLCHAN, E. T., & ROBINSON, M. L. (2001) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200106000-00007 · Cited by 590
The Nature of Nurture: Genetic Influence on “Environmental” Measures
Plomin, R., & Bergeman, C. S. (1991) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00070278 · Cited by 556
Sibling Comparison Designs: Bias From Non-Shared Confounders and Measurement Error
Frisell, T., Öberg, S., Kuja-Halkola, R., & Sjölander, A. (2012) · Epidemiology · doi:10.1097/ede.0b013e31825fa230 · Cited by 551
Developmental Psychopathology: Reactions, Reflections, Projections
Cicchetti, D. (1993) · Developmental Review · doi:10.1006/drev.1993.1021 · Cited by 535
Causal Inference and Observational Research: The Utility of Twins
McGue, M., Osler, M., & Christensen, K. (2010) · Perspectives on Psychological Science · doi:10.1177/1745691610383511 · Cited by 529
Testing hypotheses on specific environmental causal effects on behavior.
Rutter, M. L., Pickles, A. R., Murray, R. M., & Eaves, L. J. (2001) · Psychological Bulletin · doi:10.1037/0033-2909.127.3.291 · Cited by 515
Prenatal Stress and Risk for Psychopathology: Specific Effects or Induction of General Susceptibility?
Huizink, A. C., Mulder, E. J. H., & Buitelaar, J. K. (2004) · Psychological Bulletin · doi:10.1037/0033-2909.130.1.115 · Cited by 473
Maternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring
Huizink, A. C., & Mulder, E. J. H. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.04.005 · Cited by 468
Model-fitting approaches to the analysis of human behaviour
Eaves, L. J., Last, K. A., Young, P. A., & Martin, N. G. (1978) · Heredity · doi:10.1038/hdy.1978.101 · Cited by 457
Confirming Unexpressed Genotypes for Schizophrenia
Gottesman, I. I. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810100009002 · Cited by 449
Combined Linkage and Association Sib-Pair Analysis for Quantitative Traits
Fulker, D. W., Cherny, S. S., Sham, P. C., & Hewitt, J. K. (1999) · The American Journal of Human Genetics · doi:10.1086/302193 · Cited by 443
Physical and mental health outcomes of prenatal maternal stress in human and animal studies: a review of recent evidence
Beydoun, H. A., & Saftlas, A. F. (2008) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.2008.00951.x · Cited by 431
Proceeding From Observed Correlation to Causal Inference: The Use of Natural Experiments
Rutter, M. L. (2007) · Perspectives on Psychological Science · doi:10.1111/j.1745-6916.2007.00050.x · Cited by 409
Maternal smoking during pregnancy and severe antisocial behavior in offspring: a review
Wakschlag, L. S., Pickett, K. E., Cook, E., Benowitz, N. L., & Leventhal, B. L. (2002) · American Journal of Public Health · doi:10.2105/ajph.92.6.966 · Cited by 371
GENES, BEHAVIOR, AND THE SOCIAL ENVIRONMENT: MOVING BEYOND THE NATURE/NURTURE DEBATE
Hernandez, L. M., & Blazer, D. G. (2006) · doi:10.13016/tt5y-fgvl · Cited by 351
Gene-Environment Interaction in Psychological Traits and Disorders
Dick, D. M. (2011) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032210-104518 · Cited by 311
Prenatal Smoking Might Not Cause Attention-Deficit/Hyperactivity Disorder: Evidence from a Novel Design
Thapar, A., Rice, F., Hay, D., Boivin, J., Langley, K., van den Bree, M. V. D., Rutter, M., & Harold, G. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.05.032 · Cited by 308
Are animal models relevant to key aspects of human parturition?
Mitchell, B. F., & Taggart, M. J. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00153.2009 · Cited by 270
Smoking during pregnancy and offspring externalizing problems: An exploration of genetic and environmental confounds
D'Onofrio, B. M., Hulle, C. A. V., Waldman, I. D., Rodgers, J. L., Harden, K. P., Rathouz, P. J., & Lahey, B. B. (2008) · Development and Psychopathology · doi:10.1017/s0954579408000072 · Cited by 267
Self-citation
Maternal Smoking During Pregnancy and Child Outcomes: Real or Spurious Effect?
Knopik, V. S. (2009) · Developmental Neuropsychology · doi:10.1080/87565640802564366 · Cited by 261
Assessing Intrauterine Influences on Offspring Health Outcomes: Can Epidemiological Studies Yield Robust Findings?
Smith, G. D. (2008) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2007.00191.x · Cited by 257
A progressive approach to non‐additivity and genotype‐environmental covariance in the analysis of human differences
Eaves, L. J., Last, K., Martin, N. G., & Jinks, J. (1977) · British Journal of Mathematical and Statistical Psychology · doi:10.1111/j.2044-8317.1977.tb00722.x · Cited by 253
The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact
Khoury, M. J., GWINN, M. L., & Ioannidis, J. P. A. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq211 · Cited by 249
Prenatal Smoking and Early Childhood Conduct Problems
Maughan, B., Taylor, A. W., Caspi, A., & Moffitt, T. E. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.8.836 · Cited by 247
Genetics and the Social Science Explanation of Individual Outcomes
Jeremy Freese, A. (2008) · American Journal of Sociology · doi:10.1086/592208 · Cited by 239
Stress, Corticotropin‐releasing Factor, and Drug Addiction
Koob, G. F. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb07876.x · Cited by 234
The role of the Children of Twins design in elucidating causal relations between parent characteristics and child outcomes
D'Onofrio, B. M., Turkheimer, E. N., Eaves, L. J., Corey, L. A., Berg, K., Solaas, M. H., & Emery, R. E. (2003) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00196 · Cited by 219
Self-citation
Testing hypotheses about direction of causation using cross-sectional family data
Heath, A. C., Kessler, R. C., Neale, M. C., Hewitt, J. K., Eaves, L. J., & Kendler, K. S. (1993) · Behavior Genetics · doi:10.1007/bf01067552 · Cited by 218
All in the family: Comparing siblings to test causal hypotheses regarding environmental influences on behavior
Lahey, B. B., & D’Onofrio, B. M. (2010) · Current Directions in Psychological Science · doi:10.1177/0963721410383977 · Cited by 207
Self-citation
Cigarette smoking during pregnancy
Shea, A. K., & Steiner, M. S. (2008) · Nicotine & Tobacco Research · doi:10.1080/14622200701825908 · Cited by 207
Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk: a female twin study
Knopik, V. S., Sparrow, E. P., Madden, P. A. F., Bucholz, K. K., Hudziak, J. J., Reich, W., Slutske, W. S., Grant, J. D., McLaughlin, T., Todorov, A. A., et al. (2005) · Psychological Medicine · doi:10.1017/s0033291704004155 · Cited by 200
Maternal Smoking during Pregnancy and Children's Cognitive and Physical Development: A Causal Risk Factor?
Gilman, S. E., Gardener, H. E., & Buka, S. L. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn175 · Cited by 172
Children of the National Longitudinal Survey of Youth: A unique research opportunity.
Chase-Lansdale, P. L., Mott, F. L., Jeanne Brooks-gunn, B., & Phillips, D. A. (1991) · Developmental Psychology · doi:10.1037/0012-1649.27.6.918 · Cited by 167
Developmental plasticity and human disease: research directions
Gluckman, P. D., & Hanson, M. A. (2007) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2007.01802.x · Cited by 167
Prenatal tobacco effects on neuropsychological outcomes among preadolescents
CORNELIUS, M. D., RYAN, C. M., DAY, N. L., GOLDSCHMIDT, L., & WILLFORD, J. A. (2001) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200108000-00002 · Cited by 163
Commentary: Advent of sibling designs
Donovan, S. J., & Susser, E. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr057 · Cited by 161
Do prenatal risk factors cause psychiatric disorder? Be wary of causal claims
Thapar, A., & Rutter, M. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.109.062828 · Cited by 155
Psychiatric Genetics: A Methodologic Critique
Kendler, K. S. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.1.3 · Cited by 143
Interaction of dopamine transporter genotype with prenatal smoke exposure on ADHD symptoms
Becker, K., El-Faddagh, M., Schmidt, M. H., Esser, G., & Laucht, M. (2008) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2007.07.004 · Cited by 142
The resolution of cultural and biological inheritance: Informativeness of different relationships
Heath, A. C., Kendler, K. S., Eaves, L. J., & Markell, D. (1985) · Behavior Genetics · doi:10.1007/bf01066238 · Cited by 141
A Genetically Informed Study of Marital Instability and Its Association With Offspring Psychopathology.
D'Onofrio, B. M., Turkheimer, E. N., Emery, R. E., Slutske, W. S., Heath, A. C., Madden, P. A. F., & Martin, N. G. (2005) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.114.4.570 · Cited by 140
Self-citation
Disentangling prenatal and inherited influences in humans with an experimental design
Rice, F. J., Harold, G. T., Boivin, J., Hay, D. F., van den Bree, M. B. M., & Thapar, A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808798106 · Cited by 137
Interaction of prenatal exposure to cigarettes and MAOA genotype in pathways to youth antisocial behavior
Wakschlag, L. S., Kistner, E. O., Pine, D. S., Biesecker, G., Pickett, K. E., Skol, A. D., Dukić, V., Blair, J., LEVENTHAL, B. L., Cox, N. J., et al. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.22 · Cited by 133
GENETIC MODELS FOR THE ANALYSIS OF DATA FROM THE FAMILIES OF IDENTICAL TWINS
Nance, W. E., & Corey, L. A. (1976) · Genetics · doi:10.1093/genetics/83.4.811 · Cited by 131
Maternal smoking during pregnancy and school performance at age 15
Lambe, M., Hultman, C., Torr??ng, A., MacCabe, J., & Cnattingius, S. (2006) · Epidemiology · doi:10.1097/01.ede.0000231561.49208.be · Cited by 124
Is maternal smoking during pregnancy a risk factor for Hyperkinetic disorder?--findings from a sibling design
Obel, C., Olsen, J. H., Henriksen, T. B., Rodriguez, A., Järvelin, M., Moilanen, I., Parner, E. T., Línnet, K., Taanila, A. M., Ebeling, H., et al. (2010) · International Journal of Epidemiology · doi:10.1093/ije/dyq185 · Cited by 118
The relationship code: Deciphering genetic and social patterns in adolescent development
Reiss, D., Neiderhiser, J. M., Hetherington, E. M., & Plomin, R. J. (2000) · Cited by 114
Family matters
Lawlor, D. A., & Mishra, G. D. (2009) · doi:10.1093/acprof:oso/9780199231034.001.0001 · Cited by 113
Effect of Maternal Smoking During Pregnancy on Offspring's Cognitive Ability: Empirical Evidence for Complete Confounding in the US National Longitudinal Survey of Youth
Batty, G., Der, G., & Deary, I. (2006) · Pediatrics · doi:10.1542/peds.2006-0168 · Cited by 104
Familial Confounding of the Association Between Maternal Smoking During Pregnancy and Offspring Criminality
D'Onofrio, B. M., Singh, A. L., Iliadou, A. N., Lambe, M. P., Hultman, C. M., Grann, M., Neiderhiser, J. M., & Lichtenstein, P. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.33 · Cited by 102
Self-citation
Orbitofrontal Cortex and Drug Use During Adolescence: Role of Prenatal Exposure to Maternal Smoking and BDNF Genotype
Lotfipour, S., Ferguson, E., Leonard, G., Perron, M., Pike, B., Richer, L., Séguin, J. R., Toro, R., Veillette, S., Pausova, Z., et al. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.124 · Cited by 102
Maternal smoking during pregnancy and risk to boys’ conduct disturbance: an examination of the causal hypothesis
Silberg, J. L., Parr, T. L. S., Neale, M. C., Rutter, M. L., Angold, A. C., & Eaves, L. J. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01477-4 · Cited by 95
Invited Commentary: The Use of Sibship Studies to Detect Familial Confounding
Susser, E., Eide, M. G., & Begg, M. D. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq196 · Cited by 85
Analysing the contributions of genes and parent–child interaction to childhood behavioural and emotional problems: a model for the children of twins
Silberg, J. L., & Eaves, L. J. (2004) · Psychological Medicine · doi:10.1017/s0033291703008948 · Cited by 84
Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects
Thapar, A., Harold, G. T., Rice, F. J., Ge, X., Boivin, J., Hay, D. F., van den Bree, M. B. M., & Lewis, A. (2007) · BMC Medical Research Methodology · doi:10.1186/1471-2288-7-25 · Cited by 82
A Quasi-Experimental Study of Maternal Smoking During Pregnancy and Offspring Academic Achievement
D'Onofrio, B. M., Singh, A. L., Iliadou, A. N., Lambe, M. P., Hultman, C. M., Neiderhiser, J. M., Långström, N., & Lichtenstein, P. (2010) · Child Development · doi:10.1111/j.1467-8624.2009.01382.x · Cited by 82
Self-citation
Analysis and Interpretation of Twin Studies Including Measures of the Shared Environment
Turkheimer, E. N., D'Onofrio, B. M., MAES, H. H. M., & Eaves, L. J. (2005) · Child Development · doi:10.1111/j.1467-8624.2005.00845.x-i1 · Cited by 81
Self-citation
Familial Confounding of the Association Between Maternal Smoking During Pregnancy and Offspring Substance Use and Problems
D'Onofrio, B. M., Rickert, M. E., Långström, N., Donahue, K., Coyne, C. A., Larsson, H., Ellingson, J. M., Hulle, C. A. V., Iliadou, A. N., Rathouz, P. J., et al. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.2107 · Cited by 73
Self-citation
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Harden, K. P., Lynch, S. K., Turkheimer, E. N., Emery, R. E., D'Onofrio, B. M., Slutske, W. S., Waldron, M., Heath, A. C., Statham, D. J., & Martin, N. G. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.4.667 · Cited by 73
Self-citation
Correlates of cigarette smoking during pregnancy and its genetic and environmental overlap with nicotine dependence
Arpana Agrawal, A., Knopik, V. S., Pergadia, M. L., Waldron, M., Bucholz, K. K., Martin, N. G., Heath, A. C., & Madden, P. A. F. (2008) · Nicotine & Tobacco Research · doi:10.1080/14622200801978672 · Cited by 70
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D'Onofrio, B. M., & Lahey, B. B. (2010) · Journal of Marriage and the Family · doi:10.1111/j.1741-3737.2010.00729.x · Cited by 70
Self-citation
Prenatal Origins of Neurological Development
Glynn, L. M., & Sandman, C. A. (2011) · Current Directions in Psychological Science · doi:10.1177/0963721411422056 · Cited by 69
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Jaffee, S. R., & Price, T. S. (2012) · Development and Psychopathology · doi:10.1017/s0954579412000685 · Cited by 67
Maternal smoking during pregnancy and intellectual performance in young adult Swedish male offspring
Lundberg, F. E., Cnattingius, S., D'Onofrio, B. M., Altman, D., Lambe, M. P., Hultman, C. M., & Iliadou, A. N. (2009) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.2009.01073.x · Cited by 67
Self-citation
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Kendler, K. S., Jaffee, S. R., & Römer, D. (2011) · Medical Entomology and Zoology · Cited by 63
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Purcell, S., & Koenen, K. C. (2005) · Behavior Genetics · doi:10.1007/s10519-004-1484-9 · Cited by 58
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Fergusson, D. M. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.3.223 · Cited by 56
Prenatal drug exposure effects on subsequent vulnerability to drug abuse
Glantz, M. D., & Chambers, J. C. (2006) · Development and Psychopathology · doi:10.1017/s0954579406060445 · Cited by 55
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Eaves, L. J., Silberg, J. L., & MAES, H. H. M. (2005) · Twin Research and Human Genetics · doi:10.1375/1832427054936736 · Cited by 54
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Meyer, K. A., Williams, P. L., Hernández–Dı́az, S., & Cnattingius, S. (2004) · Epidemiology · doi:10.1097/01.ede.0000142148.51230.60 · Cited by 52
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D'Onofrio, B. M., Hulle, C. A. V., Goodnight, J. A., Rathouz, P. J., & Lahey, B. B. (2011) · Psychological Medicine · doi:10.1017/s0033291711002443 · Cited by 52
Self-citation
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Iliadou, A. N., Koupil, I., Villamor, E., Altman, D., Hultman, C. M., Långström, N., & Cnattingius, S. (2010) · International Journal of Epidemiology · doi:10.1093/ije/dyq064 · Cited by 49
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Schermerhorn, A. C., D'Onofrio, B. M., Turkheimer, E. N., Ganiban, J. M., Spotts, E. L., Lichtenstein, P., Reiss, D., & Neiderhiser, J. M. (2010) · Developmental Psychology · doi:10.1037/a0021362 · Cited by 46
Self-citation
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Lahey, B. B., D’Onofrio, B. M., & Waldman, I. D. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01980.x · Cited by 45
Self-citation
The Early Growth and Development Study: Using the Prospective Adoption Design to Examine Genotype–Environment Interplay
Leve, L. D., Neiderhiser, J. M., Scaramella, L. V., & Reiss, D. (2010) · Behavior Genetics · doi:10.1007/s10519-010-9353-1 · Cited by 43
Translational Epidemiology in Psychiatry
Weissman, M. M., Brown, A. S., & Talati, A. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.47 · Cited by 43
Maternal Cigarette Smoking during Pregnancy and Offspring Externalizing Behavioral Problems: A Propensity Score Matching Analysis
Boutwell, B. B., & Beaver, K. M. (2010) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph7010146 · Cited by 42
Maternal Smoking and Infant Mortality
Johansson, A. L. V., Dickman, P. W., Kramer, M. S., & Cnattingius, S. (2009) · Epidemiology · doi:10.1097/ede.0b013e31819dcc6a · Cited by 40
Genome Wide Association Studies of Behavior are Social Science
Turkheimer, E. (2012) · Boston studies in the philosophy of science · doi:10.1007/978-94-007-1951-4_3 · Cited by 38
Self-citation
The hunt for gene effects pertinent to behavioral traits and psychiatric disorders: From mouse to human
Wahłsten, D. (2012) · Developmental Psychobiology · doi:10.1002/dev.21043 · Cited by 38
Genetic Interactions with Prenatal Social Environment
Conley, D., & Rauscher, E. A. (2013) · Journal of Health and Social Behavior · doi:10.1177/0022146512473758 · Cited by 34
Give Us This Day Our Daily Breadth
Duncan, G. J. (2012) · Child Development · doi:10.1111/j.1467-8624.2011.01679.x · Cited by 33
Disentangling the relationships between maternal smoking during pregnancy and co-occurring risk factors
Ellingson, J. M., Rickert, M. E., Lichtenstein, P., Långström, N., & D'Onofrio, B. M. (2011) · Psychological Medicine · doi:10.1017/s0033291711002534 · Cited by 31
Self-citation
Prenatal smoking exposure and offspring stress coping in late adolescence: no causal link
Kuja‐Halkola, R., D'Onofrio, B. M., Iliadou, A. N., Långström, N., & Lichtenstein, P. (2010) · International Journal of Epidemiology · doi:10.1093/ije/dyq133 · Cited by 28
Self-citation
Invited Commentary: The Epicenter of Translational Science
Hiatt, R. A. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq212 · Cited by 26
The Evolution of Population Science
Gaziano, J. M. (2010) · JAMA · doi:10.1001/jama.2010.1691 · Cited by 24
Maternal smoking during pregnancy and risks of suicidal acts in young offspring
Cnattingius, S., Svensson, T., Granath, F. N., & Iliadou, A. N. (2011) · European Journal of Epidemiology · doi:10.1007/s10654-011-9556-7 · Cited by 22
Genetic Interactions with Prenatal Social Environment: Effects on Academic and Behavioral Outcomes
Conley, D., & Rauscher, E. A. (2010) · National Bureau of Economic Research · doi:10.3386/w16026 · Cited by 19
Impact of addictive and harmful substances on fetal brain development
Ferriero, D. M., & Dempsey, D. A. (1999) · Current Opinion in Neurology · doi:10.1097/00019052-199904000-00006 · Cited by 17
Fetal Genotype for the Xenobiotic Metabolizing Enzyme NQO1 Influences Intrauterine Growth Among Infants Whose Mothers Smoked During Pregnancy
Price, T. S., Großer, T., Plomin, R. J., & Jaffee, S. R. (2010) · Child Development · doi:10.1111/j.1467-8624.2009.01383.x · Cited by 15
In Utero Smoking Exposure Warrants Further Investigation
Talati, A., & Weissman, M. M. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.119 · Cited by 12
Feasibility of half‐sibling designs for detecting a genetic component to a disease
Tierney, C., Merikangas, K. R., & RISCH, N. J. (1994) · Genetic Epidemiology · doi:10.1002/gepi.1370110608 · Cited by 10

Research works printed but not linked: 11

Barker DJP, 1998, Mothers, Babies and Health in Later Life
Masten AS, 2010, Dev Psychopathol
Kendler K, 2010, The Dynamic Genome and Mental Health: The Role of Genes and Environments in Development
Plomin R, 2008, Behavioral Genetics
Scarr S, 1983, Child Dev, 54, 424
Turkheimer E, Handbook of Research Methods in Personality and Social Psychology
10.1375/twin.8.4.283 · DOI
Spielman RS, 1993, Am J Hum Genet, 52, 506
Baker P, 1989, NLSY Child Handbook
Academy of Medical Sciences Working Group, 2007, Identifying the Environmental Causes of Disease: How Should We Decide What to Believe and When to Take Action?
British Academy of Science Working Group, 2010, Social Science and Family Policy

Sorted by citations

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A hierarchical causal taxonomy of psychopathology across the life span.
Lahey, B. B., Krueger, R. F., Rathouz, P. J., Waldman, I. D., & Zald, D. H. (2017) · Psychological Bulletin · doi:10.1037/bul0000069 · Cited by 443
Self-citation
Annual Research Review: Interparental conflict and youth psychopathology: an evidence review and practice focused update
Harold, G. T., & Sellers, R. (2018) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12893 · Cited by 383
Preterm Birth and Mortality and Morbidity
D'Onofrio, B. M., Class, Q. A., Rickert, M. E., Larsson, H., Långström, N., & Lichtenstein, P. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.2107 · Cited by 300
Self-citation
Paternal Age at Childbearing and Offspring Psychiatric and Academic Morbidity
D’Onofrio, B. M., Rickert, M. E., Frans, E., Kuja-Halkola, R., Almqvist, C., Sjölander, A., Larsson, H., & Lichtenstein, P. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.4525 · Cited by 282
Self-citation

See all 343

Authors: D’Onofrio, B. M., Lahey, B. B., Turkheimer, E., & Lichtenstein, P.
Affiliations: Brian M. D’Onofrio is with Indiana University, Bloomington. Benjamin B. Lahey is with the University of Chicago, Chicago, IL. Eric Turkheimer is with the University of Virginia, Charlottesville. Paul Lichtenstein is with the Karolinska Institutet, Solna, Sweden.
Karolinska Institutet (SE)
ORCID: Lahey, Benjamin B.
Turkheimer, Eric
Lichtenstein, Paul
Venue: American Journal of Public Health
Publisher: American Public Health Association
Published: 2013-10
Volume: 103
Issue: S1
Pages: S46-S55
ISSN: 0090-0036 (ISSN-L)
1541-0048
DOI: 10.2105/ajph.2013.301252
PMC: PMC3778076
OpenAlex: W2077233956
Cited by: 343
References: 114
Citations by year: 2026: 12 · 2025: 23 · 2024: 20 · 2023: 15 · 2022: 29 · 2021: 29 · 2020: 29 · 2019: 32 · 2018: 27 · 2017: 36 · 2016: 31 · 2015: 24 · 2014: 26 · 2013: 10
FWCI: 20.10
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: American Journal of Public Health (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
RePEc: Research Papers in Economics (submittedVersion)
Funders: Vetenskapsrådet
National Institutes of Health
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD061817, R01HD061384, HD061384, HD061817)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Assisted Reproductive Technology and Twin Pregnancy
Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
Keywords: genetically informed designs, family-based designs, quasi-experimental design, gene-environment interaction, environmental risk factors, causal inference, sibling comparison, in vitro fertilization, smoking during pregnancy
MeSH terms: Environmental Exposure, Family Health, Female, Humans, Pregnancy, Pregnancy Complications, Research Design, Risk Factors, Smoking, Social Sciences, Confounding Factors, Epidemiologic, Behavioral Research, Genetic Research, Gene-Environment Interaction

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Critical Need for Family-Based, Quasi-Experimental Designs in Integrating Genetic and Social Science Research

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