Clarifying the Concept of Adherence to eHealth Technology: Systematic Review on When Usage Becomes Adherence
Open accessAbstract
BACKGROUND: In electronic health (eHealth) evaluations, there is increasing attention for studying the actual usage of a technology in relation to the outcomes found, often by studying the adherence to the technology. On the basis of the definition of adherence, we suggest that the following three elements are necessary to determine adherence to eHealth technology: (1) the ability to measure the usage behavior of individuals; (2) an operationalization of intended use; and (3) an empirical, theoretical, or rational justification of the intended use. However, to date, little is known on how to operationalize the intended usage of and the adherence to different types of eHealth technology. OBJECTIVE: The study aimed to improve eHealth evaluations by gaining insight into when, how, and by whom the concept of adherence has been used in previous eHealth evaluations and finding a concise way to operationalize adherence to and intended use of different eHealth technologies. METHODS: A systematic review of eHealth evaluations was conducted to gain insight into how the use of the technology was measured, how adherence to different types of technologies was operationalized, and if and how the intended use of the technology was justified. Differences in variables between the use of the technology and the operationalization of adherence were calculated using a chi-square test of independence. RESULTS: In total, 62 studies were included in this review. In 34 studies, adherence was operationalized as "the more use, the better," whereas 28 studies described a threshold for intended use of the technology as well. Out of these 28, only 6 reported a justification for the intended use. The proportion of evaluations of mental health technologies reporting a justified operationalization of intended use is lagging behind compared with evaluations of lifestyle and chronic care technologies. The results indicated that a justification of intended use does not require extra measurements to determine adherence to the technology. CONCLUSIONS: The results of this review showed that to date, justifications for intended use are often missing in evaluations of adherence. Evidently, it is not always possible to estimate the intended use of a technology. However, such measures do not meet the definition of adherence and should therefore be referred to as the actual usage of the technology. Therefore, it can be concluded that adherence to eHealth technology is an underdeveloped and often improperly used concept in the existing body of literature. When defining the intended use of a technology and selecting valid measures for adherence, the goal or the assumed working mechanisms should be leading. Adherence can then be standardized, which will improve the comparison of adherence rates to different technologies with the same goal and will provide insight into how adherence to different elements contributed to the outcomes.
AI snapshot
Written from the paper’s full text.
TL;DR
This systematic review of 62 eHealth evaluations finds that adherence is often operationalized as “the more use, the better” without an intended-use threshold, and even when a threshold is given, justification is usually missing. The authors argue adherence should be defined against a justified intended use tied to the technology’s goal or assumed working mechanisms.
Key findings
- Of 62 included studies, 34 used Category A (“more use, the better”), 23 provided an intended-use threshold without justification (Category B), and 5 provided a justified threshold (Category C); the abstract reports 6 justified among 28 threshold studies.
- Mental health technologies lagged: 20/31 had Category A operationalizations, while Category C was more equally distributed across mental health, lifestyle, and chronic care.
- Most operationalizations used ≤2 measures (49/62); 10/13 with ≥3 measures were Category A. Adherence to unstructured technologies more often used logins/sessions (P=.03), features accessed/used (P<.001), and time spent (P<.001); structured technologies used modules/lessons completed (P<.001).
- Technologies were mostly Web-based (51/62); 29 were structured, 18 unstructured, and 15 hybrid, with half targeting mental health.
Methods
- Systematic review; searched Scopus, Web of Science, ScienceDirect, and PsycINFO; 7005 records identified, 62 full texts included after title, abstract, and full-text screening.
- Included health-related technologies intended for repeated use, with objective quantifiable usage measures and an adherence operationalization; excluded offline treatment adherence, protocol adherence, simple information-exchange tools, conference abstracts, and unavailable full texts.
- Data were extracted and adherence operationalizations categorized as A/B/C; differences were tested with chi-square test of independence, using Monte Carlo correction when expected counts were low, at alpha .05.
Limitations
- Stated: only studies using adherence as an outcome or explicitly stating a proxy were included, so studies using related terms (nonusage attrition, engagement, drop-out, [non]usage) may have been missed.
- Stated: adherence operationalizations were categorized per study, not per technology, though the same technology could have different operationalizations across studies.
- Evident from the text: the abstract and results differ on the number of justified operationalizations (6 vs 5), and the review is descriptive/categorical without meta-analytic synthesis.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
0 of 34 cited sources checked · 0 supported · 0 flagged
- Findingown data
Most Category A operationalizations contain a measure for the number of modules that the users accessed or completed (19/34).
“Most Category A operationalizations contain a measure for the number of modules that the users accessed or completed (19/34)”
Quote in the paperNot a substantial claim - Findingown data
Category C definitions are mostly based on the number of accessed or completed modules (3/5 operationalizations).
“Category C definitions are mostly based on the number of accessed or completed modules (3/5 operationalizations).”
Quote in the paperNot a substantial claim - Findingown data
Justifications of intended use are often based on the goal of the technology and/or the assumed working mechanisms, leading to more focused operationalizations that do not require additional measurements to evaluate adherence to the technology.
“In contrast, the results indicated that justifications of intended use are often based on the goal of the technology and/or the assumed working mechanisms, leading to more focused operationalizations that do not require additional measurements to evaluate adherence to the technology.”
Quote in the paperSubstantial claim - Findingown data
In 34 studies, adherence was operationalized as "the more use, the better" (Category A).
“In 34 studies, adherence was operationalized as “the more use, the better,””
- Also stated in: § Operationalization of the Adherence Definition · plain
“Out of the 62 included articles, 34 reported adherence only in terms of how often the technology was used (Category A operationalization)”
Quote in the paperSubstantial claim - Also stated in: § Operationalization of the Adherence Definition · plain
- Findingown data
Out of the 28 studies that described a threshold for intended use, only 6 reported a justification for the intended use.
“Out of these 28, only 6 reported a justification for the intended use.”
Quote in the paperSubstantial claim
- Findingown data
Most Category B operationalizations contain the number of logins or sessions (4/23).
“and the number of logins or sessions (4/23).”
Quote in the paperNot a substantial claim - Findingnone given
To date, little is known about how to operationalize the intended usage of and thus the adherence to different types of eHealth technology.
“However, to date, little is known on how to operationalize the intended usage of and the adherence to different types of eHealth technology.”
- Also stated in: § Determining Adherence · plain
“However, to date, little is known about how to operationalize the intended usage of and thus the adherence to different types of eHealth technology.”
Quote in the paperSubstantial claim - Also stated in: § Determining Adherence · plain
- Findingown data
Most Category B operationalizations contain the number of days, weeks, or months that people used the technology (11/23).
“Most Category B operationalizations contain the number of days, weeks, or months that people used the technology (11/23)”
Quote in the paperNot a substantial claim - Findingown data
The number of logins and the number of days, weeks, or months that people used the technology were used in 2 out of 5 Category C operationalizations.
“The number of logins and the number of days, weeks, or months that people used the technology were used in 2 out of 5 operationalizations.”
Quote in the paperNot a substantial claim - Findingown data
Most Category C operationalizations consist of one or two measures.
“whereas most Category C operationalizations consist of one or two measures.”
Quote in the paperSubstantial claim - Findingown data
Adherence to unstructured technologies was mostly operationalized using the number of features accessed or used (P<.001).
“Adherence to unstructured technologies was mostly operationalized using the number of logins or sessions (P=.03), the number of features accessed or used (P<.001), and the time spent using the technology (P<.001).”
Quote in the paperNot a substantial claim - Findingown data
Most Category A operationalizations contain a measure for the time spent on the technology (11/34).
“and the time spent on the technology and number of features accessed and used (both 11/34).”
Quote in the paperNot a substantial claim - Findingown data
Most of the unstructured technologies were aimed at lifestyle support (13/18).
“Most of the unstructured technologies were aimed at lifestyle support (13/18).”
Quote in the paperNot a substantial claim - Findingown data
Most Category A operationalizations contain a measure for the number of features accessed and used (11/34).
“and the time spent on the technology and number of features accessed and used (both 11/34).”
Quote in the paperNot a substantial claim - Findingown data
Justifications for intended use are often missing in evaluations of adherence.
“The results of this review showed that to date, justifications for intended use are often missing in evaluations of adherence.”
Quote in the paperSubstantial claim - Findingown data
Most operationalizations of adherence are based on a maximum of two different measures, regardless of the category (49/62).
“Most operationalizations of adherence are based on a maximum of two different measures, regardless of the category (49/62).”
Quote in the paperNot a substantial claim - Findingnone given
A justification of intended use does not require extra measurements to determine adherence to the technology.
“The results indicated that a justification of intended use does not require extra measurements to determine adherence to the technology.”
Quote in the paperNot a substantial claim - Findingown data
In 28 studies, a threshold for intended use of the technology was described as well.
“whereas 28 studies described a threshold for intended use of the technology as well.”
- Also stated in: § Operationalization of the Adherence Definition · plain
“In 23 studies, the intended usage was described as well (Category B operationalization) [51-73], and 5 studies reported the intended usage with a justification for this threshold (Category C operationalization) [74-78].”
Quote in the paperNot a substantial claim - Also stated in: § Operationalization of the Adherence Definition · plain
- Findingown data
When the operationalization of adherence consists of a combination of four or more measures, it is most likely a Category A operationalization.
“When the operationalization of adherence consists of a combination of four or more measures, it is most likely a Category A operationalization”
Quote in the paperSubstantial claim - Findingown data
The number of publications reporting Category C operationalizations has increased since 2015.
“The number of publications reporting Category C operationalizations has increased since 2015 (Figure 2).”
- Also stated in: § Principal Findings · plain
“we were still able to observe a small increase in Category C operationalizations since 2015.”
Quote in the paperNot a substantial claim - Also stated in: § Principal Findings · plain
- Findingown data
Out of the 62 included articles, 5 studies reported the intended usage with a justification for this threshold (Category C operationalization).
“and 5 studies reported the intended usage with a justification for this threshold (Category C operationalization)”
Quote in the paperNot a substantial claim - Findingown data
Ten out of 13 operationalizations that feature 3 or more measures are categorized as Category A.
“Ten out of 13 operationalizations that feature 3 or more measures are categorized as Category A.”
Quote in the paperNot a substantial claim - Findingown data
Adherence to structured technologies was most often operationalized using the number of modules or lessons completed (P<.001).
“Adherence to structured technologies was most often operationalized using the number of modules or lessons completed (P<.001).”
Quote in the paperNot a substantial claim - Findingown data
The proportion of evaluations of mental health technologies reporting a justified operationalization of intended use is lagging behind compared with evaluations of lifestyle and chronic care technologies.
“The proportion of evaluations of mental health technologies reporting a justified operationalization of intended use is lagging behind compared with evaluations of lifestyle and chronic care technologies.”
- Also stated in: § Principal Findings · plain
“Remarkably, the proportion of evaluations of mental health technologies reporting a justified (Category C) operationalization of intended use is lagging behind compared with evaluations of lifestyle and chronic care technologies.”
Quote in the paperSubstantial claim - Also stated in: § Principal Findings · plain
- Findingown data
Adherence to unstructured technologies was mostly operationalized using the number of logins or sessions (P=.03).
“Adherence to unstructured technologies was mostly operationalized using the number of logins or sessions (P=.03)”
Quote in the paperNot a substantial claim - Findingown data
We did not find a justification of intended use based on existing models for behavior change.
“The fact that we did not find a justification of intended use based on existing models for behavior change was unexpected.”
Quote in the paperSubstantial claim - Findingown data
When the intended use for the technology was reported, only a minority of all included studies featured justified Category C operationalizations.
“When the intended use for the technology was reported, only a minority of all included studies featured justified Category C operationalizations”
Quote in the paperSubstantial claim - Findingreasoning
Category C or justified operationalizations are more often defined by the number of days, weeks, or months that the technology is used by people.
“Category C or justified operationalizations are more often defined by the number of days, weeks, or months that the technology is used by people.”
Quote in the paperSubstantial claim - Findingnone given
No significant differences were found between the kinds of measures used for the three levels of operationalizations.
“No significant differences could be found between the kinds of measures that are used for all three levels of operationalizations.”
Quote in the paperNot a substantial claim - Findingreasoning
Category C operationalizations are used for a large proportion of unstructured and hybrid technologies.
“Category C operationalizations are used for a large proportion of unstructured and hybrid technologies.”
Quote in the paperSubstantial claim - Findingreasoning
Category A operationalizations are mostly used for structured or hybrid mental health interventions consisting of different modules that users have to follow.
“this level of operationalization is mostly used for structured or hybrid mental health interventions consisting of different modules that users have to follow.”
Quote in the paperNot a substantial claim - Findingcitation
There is a growing number of studies that studied adherence to eHealth technologies since Eysenbach's plea for reporting the levels of nonusage attrition with eHealth technology in 2005.
“We observed a growing number of studies that studied adherence to eHealth technologies since Eysenbach’s plea for reporting the levels of nonusage attrition with eHealth technology in 2005 [9].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [9] source
Not checked in the free run.
- Findingreasoning
The included Category C operationalizations showed that knowledge of the working mechanisms of the technology is not a prerequisite for defining the intended use.
“the included Category C operationalizations did show that knowledge of the working mechanisms of the technology is not a prerequisite for defining the intended use.”
Quote in the paperSubstantial claim - Findingreasoning
Category A operationalizations most often contain the number of modules started or completed, the number of features accessed or used, and the time spent online.
“Category A operationalizations most often contain the number of modules that a user started or completed, the number of features accessed or used, and the time spent online.”
Quote in the paperNot a substantial claim - Findingown data
Category A and B operationalizations of adherence often do not take the characteristics of the technology (eg, goal, persuasiveness, and user-friendliness) into account.
“the results of this review indicate that Category A and B operationalizations of adherence often do not take the characteristics of the technology (eg, goal, persuasiveness, and user-friendliness) into account.”
Quote in the paperSubstantial claim - Findingnone given
When the intended use of a technology was defined, the goal of the technology and/or the assumed working mechanisms often formed the starting point for selecting valid measures.
“When the intended use of a technology was defined, the goal of the technology and/or the assumed working mechanisms often formed the starting point for selecting valid measures (eg, number of logins, number of completed modules).”
Quote in the paperSubstantial claim - Findingnone given
All of the measures for adherence in this review are based on data regarding technology usage.
“All of the measures for adherence in this review are based on data regarding technology usage.”
Quote in the paperSubstantial claim - Findingown data
A limited but deliberate set of only one or two different measures in accordance with the goal of the technology can also be used for operationalizing intended use.
“the results of this review show that a limited but deliberate set of only one or two different measures in accordance with the goal of the technology can also be used for operationalizing intended use.”
Quote in the paperSubstantial claim - Interpretationreasoning
For many Category A operationalizations, a scattershot approach was used when it comes to measuring adherence.
“This implies that for many Category A operationalizations, a scattershot approach was used when it comes to measuring adherence.”
Quote in the paperSubstantial claim - Premisecitation
A meta-analysis by Van Ballegooijen et al revealed that participants complete approximately 84% of their CBT program in both offline and online treatment.
“However, a meta-analysis of Van Ballegooijen et al revealed that participants complete approximately 84% of their CBT program in both offline and online treatment.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Van Ballegooijen et al
Not checked in the free run.
- Interpretationreasoning
More measures are not necessarily the key to knowledge if they are not sufficiently specific.
“In other words, more measures are not necessarily the key to knowledge if they are not sufficiently specific.”
Quote in the paperNot a substantial claim - Interpretationcitation
Users do not necessarily need to finish the complete CBT program to experience reduction of their complaints.
“this still implies that users do not necessarily need to finish the complete program to experience reduction of their complaints”
Quote in the paperSubstantial claim - Interpretationnone given
It is not always possible to estimate the intended use of a technology.
“Evidently, it is not always possible to estimate the intended use of a technology.”
Quote in the paperSubstantial claim - Premisecitation
The amount of use that is needed to obtain the desired outcomes may vary a lot across different user groups.
“Furthermore, the amount of use that is needed to obtain the desired outcomes may vary a lot across different user groups [6].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [6] source
Not checked in the free run.
- Premisecitation
A group of users dropped out from an intervention for reducing depressive complaints after a lesson that focused on applying newly acquired skills in practice, as doing so can be confrontational.
“Kelders et al who found that a group of users dropped out from an intervention for reducing depressive complaints after a lesson that focused on applying newly acquired skills in practice, as doing so can be confrontational [56].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [56] source
Not checked in the free run.
- Interpretationreasoning
The development of use over time would probably provide more information regarding adherence than use of the technology's content at fixed points in time only.
“the development of use over time would probably provide more information regarding adherence than use of the technology’s content at fixed points in time only.”
Quote in the paperNot a substantial claim - Premisecitation
The intended use has been operationalized by linking the positive outcomes of individual users to their usage patterns to find the most effective patterns.
“the intended use has also been operationalized by linking the (positive) outcomes of individual users to their usage patterns to find the most effective patterns [78].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [78] source
Not checked in the free run.
- Interpretationown data
The comparison of adherence across different eHealth technologies is made more complicated by the lack of justified Category C operationalizations.
“making the comparison of adherence across different eHealth technologies more complicated.”
Quote in the paperSubstantial claim - Premisecitation
Individuals may stop using the technology because they have reached their personal goals (early completers or e-attainers).
“Moreover, individuals may also stop using the technology because they have reached their personal goals (early completers or e-attainers) [11,15]”
Quote in the paperSubstantial claim0 of 2 sources checked - Interpretationreasoning
These reviews fail to provide insight into how adherence and intended use have been operationalized.
“These reviews therefore fail to provide insight into how adherence and intended use have been operationalized.”
Quote in the paperSubstantial claim - Premisecitation
Many systematic reviews gaining insight into adherence to eHealth technology focus on the extent to which individuals use different types of technology and what the reasons for nonadherence are, without a proper operationalization of intended use and adherence.
“Many systematic reviews gaining insight into adherence to eHealth technology focus on the extent to which individuals use different types of technology and what the reasons for nonadherence are, without a proper operationalization of intended use and adherence [1,6,11,16,17].”
Quote in the paperSubstantial claim0 of 5 sources checked - Interpretationreasoning
Adherence and nonusage attrition do not refer to the same or inverse concepts.
“Although adherence is related to other measures such as engagement or nonusage attrition, these terms do not refer to the same or inverse concepts.”
Quote in the paperSubstantial claim - Interpretationreasoning
Nonusage dropout is not always a consequence of losing interest.
“and nonusage dropout is thus not always a consequence of losing interest (as stated by Eysenbach) [9].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [9] source
Not checked in the free run.
- Interpretationcitation
Not using the technology as defined or implied by its creators does not necessarily mean that a participant is not using the technology at all.
“After all, not using the technology as defined or implied by its creators does not necessarily mean that a participant is not using the technology at all (as implied by the definition of nonusage attrition) [9].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [9] source
Not checked in the free run.
- Premisecitation
Adherence is a multidimensional concept, influenced by a range of technological, environmental, and individual factors altogether that cannot be evaluated by technology usage alone.
“the results of a recent literature review of theoretical perspectives on adherence showed that adherence is a multidimensional concept, influenced by a range of technological, environmental, and individual factors altogether that cannot be evaluated by technology usage alone [8,84].”
Quote in the paperSubstantial claim0 of 2 sources checked - Interpretationreasoning
When using Category B or Category C operationalizations, the actual usage of each individual can be compared with the technology's intended usage.
“When using Category B or (preferably) Category C operationalizations, the actual usage of each individual can be compared with the technology’s intended usage.”
Quote in the paperSubstantial claim - Interpretationreasoning
Dose-response relationships might become more apparent when the measures used to operationalize adherence match the goal of the technology.
“It is thus very possible that dose-response relationships might become more apparent when the measures used to operationalize adherence match the goal of the technology [82,83].”
Quote in the paperSubstantial claim0 of 2 sources checked
- Classified as probably not a substantial claim. 28
- May combine two claims. 20
- The quote only partly states this claim. 2
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataAlmost half of the technologies (29/62) were structured technologies, 18 were unstructured technologies, and 15 had a hybrid nature.
“Almost half of the technologies (29/62) were structured technologies, 18 were unstructured technologies, and 15 had a hybrid nature.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataMost of the structured technologies (17/29) and almost all hybrid technologies (12/15) were aimed at improving mental health (P<.001).
“Most of the structured technologies (17/29) and almost all hybrid technologies (12/15) were aimed at improving mental health (P<.001).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe technologies described in most of the articles are Web-based (51/62).
“The technologies described in most of the articles are Web-based (51/62).”
Quote in the paperNot a substantial claimThe quote only partly states this claim.
Findingown dataAdherence to unstructured technologies was mostly operationalized using the time spent using the technology (P<.001).
“Adherence to unstructured technologies was mostly operationalized using the number of logins or sessions (P=.03), the number of features accessed or used (P<.001), and the time spent using the technology (P<.001).”
Quote in the paperNot a substantial claimThe quote only partly states this claim.
Findingown dataMost Category B operationalizations contain the number of accessed or completed modules (8/23).
“the number of accessed or completed modules (8/23)”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataIn total, 62 studies were included in this review.
“In total, 62 studies were included in this review.”
- Also stated in: § Study Selection · plain
“After screening of the titles, abstracts, and full texts, 62 full texts were included in this review.”
Quote in the paperNot a substantial claim- Also stated in: § Study Selection · plain
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataHalf of all included articles reported adherence to mental health technologies.
“Half of all included articles reported adherence to mental health technologies.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S1 (asserted), S3 (load-bearing).
FindingcitationCarolan et al describe a protocol for a study to be conducted to understand the optimum adherence to the technology in relation to the outcomes.
“Carolan et al describe a protocol for a study to be conducted to understand the optimum adherence to the technology in relation to the outcomes [78].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [78] source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
FindingreasoningThe included Category C operationalizations provided justification in various ways.
“The included Category C operationalizations provided justification in various ways.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
FindingcitationBeatty et al considered a user to be highly adherent when a therapeutic dose of 66% of the intervention was received, and this threshold was obtained from previous studies.
“Beatty et al considered a user to be highly adherent when a therapeutic dose of 66% of the intervention was received [76]. This threshold for a therapeutic dose was obtained from previous studies.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [76] source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
FindingcitationIn the study by Mertens et al, users were seen as adherent when the technology was used in accordance with the recommendations for medication use.
“In the study by Mertens et al, technology use was represented in relation to medication use, and users were therefore seen as adherent when the technology was used in accordance with the recommendations for medication use [77].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [77] Mertens, A, 2017, Advances in Human Factors and Ergonomics in Healthcare source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
FindingcitationIn the study by Zeng et al, the technology consisted of different elements that were all evaluated as effective in other studies, and users were considered adherent if they used all elements.
“In the study by Zeng et al, the technology consisted of different elements that were all evaluated as effective in other studies [75]. Users were considered adherent if they used all elements.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [75] source
Not checked in the free run.
May combine two claims.
Findingown dataThe majority of the technologies described in the included studies were structured or hybrid Web-based interventions targeting mental health (mostly CBT interventions) or unstructured technologies for lifestyle support.
“The majority of the technologies described in these studies were structured or hybrid Web-based interventions targeting mental health (mostly cognitive behavioral therapy [CBT] interventions) or unstructured technologies for lifestyle support.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataHalf of all operationalizations are based on the assumption of "the more use, the better" and do not include a threshold for intended use.
“half of all operationalizations are based on the assumption of “the more use, the better” and do not include a threshold for intended use.”
Quote in the paperSubstantial claimMay combine two claims.
Findingnone giveneHealth evaluations often fail to demonstrate the dose-response relationship or simply define it as "the more use, the better."
“eHealth evaluations often fail to demonstrate the dose-response relationship (the usage that is minimally needed to experience certain effects) or simply define it as “the more use, the better.””
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe operationalization of intended use is mostly based on the assumption of "the more use, the better" and when a threshold of intended use is provided, justification is often missing.
“the results of this review show that the operationalization of intended use is mostly based on the assumption of “the more use, the better” and that when a threshold of intended use is provided, justification is often missing.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationcitationThere should be a threshold for intended use of a CBT technology.
“and that there should be a threshold for intended use.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningAdherence to eHealth technology is an underdeveloped and often improperly used concept in the existing body of literature.
“Therefore, it can be concluded that adherence to eHealth technology is an underdeveloped and often improperly used concept in the existing body of literature.”
- Also stated in: § Conclusions · plain
“it can be concluded that adherence to eHealth technology is an underdeveloped and often improperly used concept in the existing body of literature.”
Quote in the paperNot a substantial claim- Also stated in: § Conclusions · plain
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe majority of mental health technologies is based on (principles of) cognitive behavioral therapy (CBT), which is the most studied treatment for depression and has proven effective in many studies.
“This is unexpected because the majority of mental health technologies is based on (principles of) CBT, which is the most studied treatment for depression and has proven effective in many studies [79].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [79] Cuijpers, P, 2013, Can J Psychiatry source
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
InterpretationreasoningMeasures that do not include an operationalization of intended use do not meet the definition of adherence and should be referred to as the actual usage of the technology.
“However, such measures do not meet the definition of adherence and should therefore be referred to as the actual usage of the technology.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim. May combine two claims.
InterpretationreasoningThree elements are necessary to determine adherence to eHealth technology: (1) the ability to measure the usage behavior of individuals; (2) an operationalization of intended use; and (3) an empirical, theoretical, or rational justification of the intended use.
“On the basis of the definition of adherence, we suggest that the following three elements are necessary to determine adherence to eHealth technology: (1) the ability to measure the usage behavior of individuals; (2) an operationalization of intended use; and (3) an empirical, theoretical, or rational justification of the intended use.”
- Also stated in: § Determining Adherence · hedged
“To summarize, based on the definition of adherence, we suggest that the following three elements are necessary to determine adherence to eHealth technology: (1) the ability to measure the usage behavior of individuals; (2) an operationalization of intended use; and (3) an empirical, theoretical, or rational justification of the intended use.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [10] Sabaté, E, 2003, Adherence to long-term therapies: evidence for action
Not checked in the free run.
- Also stated in: § Determining Adherence · hedged
Classified as probably not a substantial claim.
InterpretationreasoningAccording to the definitions, the intended use is the minimum use to establish adherence.
“According to these definitions, the intended use is thus the minimum use to establish adherence.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
InterpretationcitationAn important reason for the lack of justifications for the intended use of eHealth technologies might be a lack of knowledge regarding the working mechanisms of technology-based applications.
“An important reason for the lack of justifications for the intended use of eHealth technologies might be that there is a lack of knowledge regarding the working mechanisms of technology-based applications [8].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [8] source
Not checked in the free run.
May combine two claims.
PremisecitationAdherence is mostly based on measures for usage behavior, whereas definitions of engagement usually incorporate subjective attributes of challenge, positive affect, endurability, and aesthetic and sensory appeals.
“Moreover, definitions of engagement usually incorporate the more subjective attributes of challenge, positive affect, endurability, and aesthetic and sensory appeals [12], whereas adherence is mostly based on measures for usage behavior.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [12] SmithWPlodererBWadleyGWebberSBorlandRTrajectories of Engagement and Disengagement with a Story-Based Smoking Cessation App20172017 CHI Conference on Human Factors in Computing SystemsMay 6-11, 2017Denver, ColoradoACM304556
Not checked in the free run.
May combine two claims.
InterpretationreasoningUsers do not always have to experience all of the available elements of a technology or have to use the same elements because usage goals may differ across users.
“This implies that users do not always have to experience all of the available elements of a technology or have to use the same elements because usage goals may differ across users as well.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationA technology can be designed for multiple target groups and, depending on the individual user goals and the desired outcomes, technology can be used in many different ways in terms of the features that are used, as well as the frequency, time, and place of use.
“However, a technology can be designed for multiple target groups and, depending on the individual user goals and the desired outcomes, technology can be used in many different ways in terms of the features that are used, as well as the frequency, time, and place of use [13,14].”
Quote in the paperSubstantial claim0 of 2 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationExercising for at least four times per week for 6 weeks is a minimal requirement for establishing exercise habits.
“Kaushal and Rhodes found that exercising for at least four times per week for 6 weeks is a minimal requirement for establishing exercise habits [81].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [81] source
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
PremisecitationThe intended use or therapeutic dose can be justified using existing guidelines for healthy living and medication use or using previous research regarding other technologies.
“the intended use or the “therapeutic dose” can be justified just as well using existing guidelines for healthy living and medication use [74,77] or using previous research regarding other technologies [75,76].”
Quote in the paperSubstantial claim0 of 4 sources checkedProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningA justified threshold for intended use in accordance with the goal of the technology provides information for a concise evaluation of adherence and the working mechanisms of a technology.
“A justified threshold for intended use in accordance with the goal of the technology provides information for a concise evaluation of adherence and the working mechanisms of a technology.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningJustified operationalization can be used to standardize adherence to different eHealth technologies, making it easier to compare the adherence rates of different technologies.
“Subsequently, justified operationalization (comprising multidimensional measures or not) can be used to standardize adherence to different eHealth technologies, making it easier to compare the adherence rates of different technologies.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Premisenone givenPrevious research has shown that users do not always have to experience all of the elements of a technology and that effective usage patterns might differ across users.
“Previous research has shown that users do not always have to experience all of the elements of a technology and that effective usage patterns might differ across users.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningThis approach simplifies the comparison of adherence across technologies with the same goal but different technology characteristics and a different operationalization of intended use.
“This approach simplifies the comparison of adherence across technologies with the same goal (eg, improving physical activity) but different technology characteristics (eg, features of the technology, persuasiveness, and user-friendliness) and a different operationalization of intended use.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
InterpretationreasoningDonkin et al's statement that it is difficult to compare adherence with different technologies when measures vary is based on Category A operationalizations of adherence where more use is better.
“this statement is based on Category A operationalizations of adherence where more use is better.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
InterpretationreasoningFollowing the critical lesson can be seen as an important precondition for gaining effects from using the intervention.
“following this lesson can also be seen as an important precondition for gaining effects from using the intervention.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
Interpretationnone givenAdherence and intended use can be defined in many different ways, and it is very possible for different operationalizations to be used for different studies regarding the same technology.
“adherence and intended use can be defined in many different ways, and it is very possible for different operationalizations to be used for different studies regarding the same technology.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).
InterpretationreasoningThis approach also simplifies the comparison of adherence of different users of a specific technology.
“At the same time, this approach also simplifies the comparison of adherence of different users of a specific technology.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationcitationUsing Category B or C operationalizations allows calculation of the percentage of people who adhered to the intervention, making adherence a more objective and standardized concept.
“In turn, the percentage of people who adhered to the intervention can be calculated, making adherence a more objective and standardized concept [1].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [1] source
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
Study design and conductreasoningWe only included studies that used adherence as an outcome measure or studies that explicitly stated how other outcome measures are used as a proxy for adherence.
“we only included studies that used adherence as an outcome measure or studies that explicitly stated how other outcome measures are used as a proxy for adherence.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningWe may have missed relevant studies that formulated the intended use of a technology but used other related terms for adherence.
“we may have missed relevant studies that formulated the intended use of a technology, but used other related terms for adherence (eg, nonusage attrition, engagement, drop-out, or [non]usage).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningWe defined the categories of adherence operationalizations for every study, instead of every type of technology.
“we defined the categories of adherence operationalizations for every study, instead of every type of technology.”
Quote in the paperNot a substantial claim
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Low adherence is a common challenge in web-based interventions, particularly in self-guided interventions.
“Adherence is a common challenge in web-based interventions (Sieverink et al., 2017), particularly in self-guided interventions (Karyotaki et al., 2015).”
From Efficacy of a web-based psychoeducational intervention, Fex-can sex, for young adult childhood cancer survivors with sexual dysfunction: A randomized controlled trial (2024) · cites this paper as Sieverink et al., 2017
Adherence to internet-based treatments is measured through various methods, including the number of logins.
“Adherence to internet‐based treatments is measured through various methods, including the number of logins (Sieverink et al. 2017).”
From Internet‐Based Acceptance and Commitment Therapy With Interoceptive Exposure for Panic Disorder: A Randomized Controlled Trial and Working Alliance Analysis. (2026) · cites this paper as Sieverink et al. 2017
50% seems to be an average adherence rate for eHealth interventions, and program completion rates at 20% to 40% are not uncommon.
“In addition, even though the completion rate in this study may appear relatively low, 50% seems to be an average adherence rate for eHealth interventions [69], and program completion rates at 20% to 40% are not uncommon [70].”
From Short-Term Findings From Testing EPIO, a Digital Self-Management Program for People Living With Chronic Pain: Randomized Controlled Trial (2023) · cites this paper as [70]
The citation to this paper [69] attaches to the claim that average adherence to eHealth interventions is about 50%; the 20%–40% completion-rate claim has a separate citation [70]. The Results (Study Selection and Operationalization of the Adherence Definition; page unavailable) describe 62 studies and how they defined adherence, but do not report a 50% average adherence rate. Searches for “50%” and average adherence rates found no passage establishing that figure. (LLM, conf=0.73)
Experimental — accuracy not yet measuredSieverink et al reviewed 62 papers, of which 7 were on smartphone-based interventions; 5 of those 7 were published after 2016 and 2 in 2013.
“The systematic review on usage-based adherence to eHealth interventions conducted by Sieverink et al reviewed 62 papers, of which 7 were on smartphone-based interventions [17]. Of those 7 papers, 5 were published after 2016, and the other 2 were both published in 2013.”
From A Library of Analytic Indicators to Evaluate Effective Engagement with Consumer mHealth Apps for Chronic Conditions: Scoping Review (2019) · cites this paper as [17]
Sieverink et al concluded that a limited but deliberate set of only one of 2 different indicators in accordance with the goal of the technology is sufficient to operationalize adherence.
“The authors conclude that a limited but deliberate set of only one of 2 different indicators in accordance with the goal of the technology is sufficient to operationalize adherence.”
From A Library of Analytic Indicators to Evaluate Effective Engagement with Consumer mHealth Apps for Chronic Conditions: Scoping Review (2019) · cites this paper as [17]
Sieverink et al found that over half of all reviewed studies measured adherence to eHealth interventions using a single analytic indicator, and a quarter used 2 indicators.
“In their systematic review, Sieverink et al found that over half of all reviewed studies measured adherence to eHealth interventions using a single analytic indicator, and a quarter used 2 indicators [17].”
From A Library of Analytic Indicators to Evaluate Effective Engagement with Consumer mHealth Apps for Chronic Conditions: Scoping Review (2019) · cites this paper as [17]
Sieverink et al found that the majority of studies reported adherence only in terms of how an intervention was used.
“On reviewing how researchers were operationalizing adherence, they found that the majority reported adherence only in terms of how an intervention was used.”
From A Library of Analytic Indicators to Evaluate Effective Engagement with Consumer mHealth Apps for Chronic Conditions: Scoping Review (2019) · cites this paper as [17]
Our identification of the number of measures recorded on an app as an analytic indicator of engagement deviates from previous research by Sieverink et al, which found no evidence that researchers were operationalizing constructs in this way.
“Our identification of the number of measures recorded on an app as an analytic indicator of engagement deviates from previous research by Sieverink et al on usage and adherence to eHealth interventions [17], which found no evidence that researchers were operationalizing constructs in this way.”
From A Library of Analytic Indicators to Evaluate Effective Engagement with Consumer mHealth Apps for Chronic Conditions: Scoping Review (2019) · cites this paper as [17]
The outcomes of eHealth self-management interventions seem to depend on patients' motivation and adherence.
“The outcomes of eHealth self-management interventions seem to depend on patients’ motivation and adherence [7,25,64,67].”
From Digital Self-Management in Support of Patients Living With Chronic Pain: Feasibility Pilot Study (2020) · cites this paper as [67]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Abstract reports six justified studies, but results report five
MinorThe abstract says 6 studies justified their intended-use threshold, whereas the results identify 5 Category C studies. This changes the reported number meeting the paper's justification criterion.
“Out of these 28, only 6 reported a justification for the intended use.”
“and 5 studies reported the intended usage with a justification for this threshold (Category C operationalization) [74-78].”
Category A and B denominator is one too low
MinorThere are 34 Category A and 23 Category B operationalizations, totaling 57 rather than the stated 56.
Reported 56 · recomputed 57
“Furthermore, 48 out of 56 Category A and Category B operationalizations are for Web-based technologies (whether or not in combination with other devices)”
Chronic-care percentage in Category C is incorrect
MinorTable 4 gives one chronic-care study among five Category C studies, which is 20%, not 40%.
Reported 40 · recomputed 20
“| | Chronic care (n=6) | 1 (3) | 4 (17) | 1 (40) |”
Claim of no measure differences conflicts with Table 4
MinorThe discussion says no significant differences were found between the kinds of measures used across the three categories, but Table 4 marks the days/weeks/months measure as significant (aP<.05).
“No significant differences could be found between the kinds of measures that are used for all three levels of operationalizations.”
“| | Number of days/weeks/months (n=19)a | 6 (18) | 11 (48) | 2 (40) |”
Time-spent percentage in Category C is incorrect
MinorTable 4 gives one study using time spent among five Category C studies, which is 20%, not 17%.
Reported 17 · recomputed 20
“| | Time spent (n=14) | 11 (32) | 2 (9) | 1 (17) |”
Smartphone-app count differs between prose and Table 3
MinorThe prose reports five smartphone apps, but Table 3 reports six, distributed as 3 structured, 2 unstructured, and 1 hybrid.
“Furthermore, five are smartphone apps and five are Web-based or smartphone technologies combined with other devices such as wearables.”
“| | Smartphone app (n=6) | 3 (10) | 2 (11) | 1 (7) |”
Cites
Adherence to Long‐Term Therapies: Evidence for Action
Burkhart, P. V., & Sabaté, E. (2003) · Journal of Nursing Scholarship · doi:10.1111/j.1547-5069.2003.tb00001.x · Cited by 2,526 · see citing works
Eysenbach, G. (2005) · Journal of Medical Internet Research · doi:10.2196/jmir.7.1.e11 · Cited by 2,524 · see citing works
Persuasive System Design Does Matter: a Systematic Review of Adherence to Web-based Interventions
Kelders, S. M., Kok, R. N., Ossebaard, H. C., & Van Gemert-Pijnen, J. E. (2012) · Journal of Medical Internet Research · doi:10.2196/jmir.2104 · Cited by 1,308 · see citing works
Self-citationAdherence in Internet Interventions for Anxiety and Depression
Christensen, H., Griffiths, K. M., & Farrer, L. (2009) · Journal of Medical Internet Research · doi:10.2196/jmir.1194 · Cited by 1,133 · see citing works
Cuijpers, P., Berking, M., Andersson, G., Quigley, L., Kleiboer, A., & Dobson, K. S. (2013) · The Canadian Journal of Psychiatry · doi:10.1177/070674371305800702 · Cited by 1,066 · see citing works
A Systematic Review of the Impact of Adherence on the Effectiveness of e-Therapies
Donkin, L., Christensen, H., Naismith, S. L., Neal, B., Hickie, I. B., & Glozier, N. (2011) · Journal of Medical Internet Research · doi:10.2196/jmir.1772 · Cited by 876 · see citing works
Michie, S., Yardley, L., West, R., Patrick, K., & Greaves, F. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7126 · Cited by 865 · see citing works
Zachariae, R., Lyby, M. S., Ritterband, L. M., & O'Toole, M. S. (2016) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.10.004 · Cited by 704 · cited 1× · see citing works
“Although a longer treatment duration is associated with better effects [80], this still implies that users do not necessarily need to finish the complete program to experience reduction of their complaints, and that there should be a threshold for intended use.”
BackgroundCarter, M. C., Burley, V. J., Nykjaer, C., & Cade, J. E. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2283 · Cited by 666 · see citing works
van Ballegooijen, W., Cuijpers, P., van Straten, A., Karyotaki, E., Andersson, G., Smit, J. H., & Riper, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100674 · Cited by 409 · see citing works
Titov, N., Dear, B. F., Johnston, L., Lorian, C., Zou, J., Wootton, B., Spence, J., McEvoy, P. M., & Rapee, R. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062873 · Cited by 364 · see citing works
Elbert, N. J., van Os‐Medendorp, H., van Renselaar, W., Ekeland, A. G., Roijen, L. H., Raat, H., Nijsten, T. E. C., & Pasmans, S. G. M. A. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.2790 · Cited by 350 · see citing works
Beatty, L., & Binnion, C. (2016) · International Journal of Behavioral Medicine · doi:10.1007/s12529-016-9556-9 · Cited by 347 · see citing works
Exercise habit formation in new gym members: a longitudinal study
Kaushal, N., & Rhodes, R. E. (2015) · Journal of Behavioral Medicine · doi:10.1007/s10865-015-9640-7 · Cited by 285 · see citing works
Richardson, C. R., Buis, L. R., Janney, A. W., Goodrich, D. E., Sen, A., Hess, M. L., Mehari, K. S., Fortlage, L. A., Resnick, P. J., Zikmund-Fisher, B. J., et al. (2010) · Journal of Medical Internet Research · doi:10.2196/jmir.1338 · Cited by 239 · see citing works
Adherence in Internet-based interventions.
(2008) · PubMed Central · Cited by 215 · see citing works
Agile science: creating useful products for behavior change in the real world
Hekler, E. B., Klasnja, P., Riley, W. T., Buman, M. P., Huberty, J., Rivera, D. E., & Martin, C. A. (2016) · Translational Behavioral Medicine · doi:10.1007/s13142-016-0395-7 · Cited by 208 · see citing works
Christensen, H., Griffiths, K., Groves, C., & Korten, A. (2006) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2006.01743.x · Cited by 201 · see citing works
Nijland, N., van Gemert-Pijnen, J. E., Kelders, S. M., Brandenburg, B. J., & Seydel, E. R. (2011) · Journal of Medical Internet Research · doi:10.2196/jmir.1603 · Cited by 175 · see citing works
Self-citationThe Law of Attrition Revisited
Christensen, H., & Mackinnon, A. (2006) · Journal of Medical Internet Research · doi:10.2196/jmir.8.3.e20 · Cited by 161 · see citing works
Mohr, D., Duffecy, J., Ho, J., Kwasny, M., Cai, X., Burns, M., & Begale, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070086 · Cited by 156 · see citing works
Neil, A. L., Batterham, P., Christensen, H., Bennett, K., & Griffiths, K. M. (2009) · Journal of Medical Internet Research · doi:10.2196/jmir.1050 · Cited by 152 · cited 1× · see citing works
“Out of the 62 included articles, 34 reported adherence only in terms of how often the technology was used (Category A operationalization) [7,18-50].”
BackgroundMoller, A. C., Merchant, G., Conroy, D. E., West, R., Hekler, E., Kugler, K. C., & Michie, S. (2017) · Journal of Behavioral Medicine · doi:10.1007/s10865-016-9818-7 · Cited by 151 · see citing works
Lillevoll, K. R., Vangberg, H. C. B., Griffiths, K. M., Waterloo, K., & Eisemann, M. R. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-14 · Cited by 150 · cited 1× · see citing works
“Out of the 62 included articles, 34 reported adherence only in terms of how often the technology was used (Category A operationalization) [7,18-50].”
BackgroundPredictors of adherence among community users of a cognitive behavior therapy website.
(2008) · PubMed Central · Cited by 142 · see citing works
Neve, M. J., Collins, C. E., & Morgan, P. J. (2010) · Journal of Medical Internet Research · doi:10.2196/jmir.1640 · Cited by 137 · see citing works
Attrition Revisited: Adherence and Retention in a Web-Based Alcohol Trial
Murray, E., White, I. R., Varagunam, M., Godfrey, C., Khadjesari, Z., & McCambridge, J. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2336 · Cited by 131 · see citing works
Beishuizen, C. R., Stephan, B. C., van Gool, W. A., Brayne, C., Peters, R. J., Andrieu, S., Kivipelto, M., Soininen, H., Busschers, W. B., Moll van Charante, E. P., et al. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5218 · Cited by 128 · see citing works
Alfonsson, S., Olsson, E., & Hursti, T. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5352 · Cited by 118 · see citing works
Get with the program: Adherence to a smartphone app for smoking cessation
Zeng, E. Y., Heffner, J. L., Copeland, W. K., Mull, K. E., & Bricker, J. B. (2016) · Addictive Behaviors · doi:10.1016/j.addbeh.2016.07.007 · Cited by 117 · see citing works
Zarski, A.-C., Lehr, D., Berking, M., Riper, H., Cuijpers, P., & Ebert, D. D. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.4493 · Cited by 114 · cited 1× · see citing works
“In 23 studies, the intended usage was described as well (Category B operationalization) [51-73], and 5 studies reported the intended usage with a justification for this threshold (Category C operationalization) [74-78].”
BackgroundExperiences of non-adherence to Internet-delivered cognitive behavior therapy: a qualitative study
Johansson, O., Michel, T., Andersson, G., & Paxling, B. (2015) · Internet Interventions · doi:10.1016/j.invent.2015.02.006 · Cited by 99 · cited 1× · see citing works
“Out of the 62 included articles, 34 reported adherence only in terms of how often the technology was used (Category A operationalization) [7,18-50].”
BackgroundEl Alaoui, S., Ljótsson, B., Hedman, E., Kaldo, V., Andersson, E., Rück, C., Andersson, G., & Lindefors, N. (2015) · PLOS ONE · doi:10.1371/journal.pone.0124258 · Cited by 98 · see citing works
The Ins and Outs of an Online Bipolar Education Program: A Study of Program Attrition
Nicholas, J., Proudfoot, J., Parker, G., Gillis, I., Burckhardt, R., Manicavasagar, V., & Smith, M. (2010) · Journal of Medical Internet Research · doi:10.2196/jmir.1450 · Cited by 97 · see citing works
Wanner, M., Martin‐Diener, E., Bauer, G. F., Braun‐Fahrländer, C., & Martin, B. W. (2010) · Journal of Medical Internet Research · doi:10.2196/jmir.1361 · Cited by 95 · see citing works
Mattila, E., Orsama, A.-L., Ahtinen, A., Hopsu, L., Leino, T., & Korhonen, I. (2013) · JMIR mhealth and uhealth · doi:10.2196/mhealth.2557 · Cited by 93 · see citing works
Kooistra, L. C., Ruwaard, J., Wiersma, J. E., van Oppen, P., van der Vaart, R., van Gemert-Pijnen, J. E. W. C., & Riper, H. (2016) · Internet Interventions · doi:10.1016/j.invent.2016.01.003 · Cited by 92 · see citing works
Kelders, S. M., Bohlmeijer, E. T., & Van Gemert-Pijnen, J. E. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2258 · Cited by 88 · see citing works
Self-citationOpening the Black Box of Electronic Health: Collecting, Analyzing, and Interpreting Log Data
Sieverink, F., Kelders, S., Poel, M., & van Gemert-Pijnen, L. (2017) · JMIR Research Protocols · doi:10.2196/resprot.6452 · Cited by 88 · see citing works
Self-citationAttrition in web-based treatment for problem drinkers
Postel, M. G., de Haan, H. A., ter Huurne, E. D., van der Palen, J., Becker, E. S., & de Jong, C. A. (2011) · Journal of Medical Internet Research · doi:10.2196/jmir.1811 · Cited by 87 · see citing works
Ho, F. Y., Chung, K., Yeung, W., Ng, T. H., & Cheng, S. K.-W. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.10.002 · Cited by 86 · see citing works
Theoretical Perspectives of Adherence to Web-Based Interventions: a Scoping Review
Ryan, C., Bergin, M., & Wells, J. S. (2018) · International Journal of Behavioral Medicine · doi:10.1007/s12529-017-9678-8 · Cited by 86 · see citing works
Van Gemert-Pijnen, J. E., Kelders, S. M., & Bohlmeijer, E. T. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.2991 · Cited by 84 · cited 1× · see citing works
“It is thus very possible that dose-response relationships might become more apparent when the measures used to operationalize adherence match the goal of the technology [82,83].”
BackgroundSelf-citationNoone, C., & Hogan, M. (2016) · BMC Psychology · doi:10.1186/s40359-016-0122-7 · Cited by 81 · see citing works
Jander, A., Crutzen, R., Mercken, L. A. G., Candel, M. J. J. M., & de Vries, H. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.4708 · Cited by 75 · see citing works
Do adherence variables predict outcome in an online program for the prevention of eating disorders?
Manwaring, J. L., Bryson, S. W., Goldschmidt, A. B., Winzelberg, A. J., Luce, K. H., Cunning, D., Wilfley, D. E., & Taylor, C. B. (2008) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.76.2.341 · Cited by 73 · see citing works
Ware, L. J., Hurling, R., Bataveljic, O., Fairley, B. W., HURST, T. L., Murray, P., Rennie, K. L., Tomkins, C. E., Finn, A., Cobain, M. R., et al. (2008) · Journal of Medical Internet Research · doi:10.2196/jmir.1108 · Cited by 65 · see citing works
Alley, S., Jennings, C. A., Plotnikoff, R. C., & Vandelanotte, C. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5664 · Cited by 63 · see citing works
Hadjiconstantinou, M., Byrne, J. L., Bodicoat, D. H., Robertson, N., Eborall, H., Khunti, K. K., & Davies, M. J. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5991 · Cited by 63 · see citing works
Self-managed eHealth Disease Monitoring in Children and Adolescents with Inflammatory Bowel Disease
Carlsen, K., Jakobsen, C., Houen, G., Kallemose, T., Pærregaard, A., Riis, L. B., Munkholm, P., & Wewer, V. (2017) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000001026 · Cited by 63 · see citing works
Reinwand, D. A., Schulz, D. N., Crutzen, R., Kremers, S. P., & de Vries, H. (2015) · Journal of Medical Internet Research · doi:10.2196/jmir.3932 · Cited by 62 · see citing works
Web-based depression treatment: Associations of clients׳ word use with adherence and outcome
van der Zanden, R. A., Curie, K., van Londen, M., Kramer, J., Steen, G. J., & Cuijpers, P. J. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.01.005 · Cited by 60 · see citing works
Schulz, A., Stolz, T., Vincent, A., Krieger, T., Andersson, G., & Berger, T. (2016) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.07.001 · Cited by 59 · see citing works
Strategies for increasing adherence to an online smoking cessation intervention for college students
An, L. C., Perry, C. L., Lein, E., Klatt, C. M., Farley, D. M., Bliss, R., Hennrikus, D. J., Pallonen, U. E., Lando, H. A., Ahluwalia, J. S., et al. (2006) · Nicotine & Tobacco Research · doi:10.1080/14622200601039881 · Cited by 58 · see citing works
Kooij, L., Groen, W. G., & van Harten, W. H. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7405 · Cited by 56 · see citing works
van den Berg, S. W., Peters, E. J., Kraaijeveld, J. F., Gielissen, M. F., & Prins, J. B. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2566 · Cited by 53 · see citing works
Graham, A. L., Papandonatos, G. D., Cha, S., Erar, B., Amato, M. S., Cobb, N. K., NIAURA, R. S., & Abrams, D. B. (2016) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntw282 · Cited by 52 · see citing works
Price, M., Gros, D. F., McCauley, J. L., Gros, K. S., & Ruggiero, K. J. (2012) · Psychiatry: Interpersonal and Biological Processes · doi:10.1521/psyc.2012.75.3.267 · Cited by 49 · see citing works
Farrer, L. M., Griffiths, K. M., Christensen, H., Mackinnon, A. J., & Batterham, P. J. (2014) · Cognitive Therapy and Research · doi:10.1007/s10608-013-9589-1 · Cited by 47 · cited 1× · see citing works
“In 23 studies, the intended usage was described as well (Category B operationalization) [51-73], and 5 studies reported the intended usage with a justification for this threshold (Category C operationalization) [74-78].”
BackgroundBeatty, L., Kemp, E., Binnion, C., Turner, J., Milne, D., Butow, P., Lambert, S., Yates, P., Yip, D., & Koczwara, B. (2017) · Supportive Care in Cancer · doi:10.1007/s00520-017-3591-1 · Cited by 46 · see citing works
Cruz, V. T., Pais, J. L., Alves, I., Ruano, L., Mateus, C., Barreto, R. D., Bento, V., Colunas, M., Rocha, N. P., & Coutinho, P. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3377 · Cited by 43 · see citing works
Schuster, R., Leitner, I., Carlbring, P., & Laireiter, A.-R. (2017) · Internet Interventions · doi:10.1016/j.invent.2017.04.001 · Cited by 42 · see citing works
Hayman, M., Reaburn, P. R. J., Browne, M., Vandelanotte, C., Alley, S., & Short, C. E. (2017) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-017-1277-9 · Cited by 39 · see citing works
Improving adherence to web-based cessation programs: a randomized controlled trial study protocol
Graham, A. L., Cha, S., Papandonatos, G. D., Cobb, N. K., Mushro, A., Fang, Y., NIAURA, R. S., & Abrams, D. B. (2013) · Trials · doi:10.1186/1745-6215-14-48 · Cited by 38 · see citing works
Nordin, C. A., Michaelson, P., Gard, G., & Eriksson, M. K. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5634 · Cited by 38 · see citing works
Individual and Household Predictors of Adolescents’ Adherence to a Web-Based Intervention
Mâsse, L. C., Watts, A. W., Barr, S. I., Tu, A. W., Panagiotopoulos, C., Geller, J., & Chanoine, J. (2014) · Annals of Behavioral Medicine · doi:10.1007/s12160-014-9658-z · Cited by 34 · see citing works
Program Use and Outcome Change in a Web-Based Trauma Intervention: Individual and Social Factors
Wang, Z., Wang, J., & Maercker, A. R. A. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5839 · Cited by 32 · see citing works
A comparison of MOVE! versus TeleMOVE programs for weight loss in Veterans with obesity
Rutledge, T. R., Skoyen, J. A., Wiese, J. A., Ober, K. M., & Woods, G. N. (2016) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2016.11.005 · Cited by 32 · see citing works
Price, M., Davidson, T. M., Andrews, J. O., & Ruggiero, K. J. (2013) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x13476230 · Cited by 28 · see citing works
Tu, A. W., Watts, A. W., Chanoine, J., Panagiotopoulos, C., Geller, J., Brant, R., Barr, S. I., & Mâsse, L. C. (2017) · BMC Public Health · doi:10.1186/s12889-017-4220-0 · Cited by 28 · see citing works
Graham, A. L., Jacobs, M. A., Cohn, A. M., Cha, S., Abroms, L. C., Papandonatos, G. D., & Whittaker, R. (2016) · BMJ Open · doi:10.1136/bmjopen-2015-010687 · Cited by 26 · see citing works
Fernandes‐Taylor, S., Gunter, R. L., Bennett, K. M., Awoyinka, I., Rahman, S., Greenberg, C. C., & Kent, K. C. (2017) · JMIR Research Protocols · doi:10.2196/resprot.6819 · Cited by 26 · see citing works
Alfonsson, S., Olsson, E. M. G., Linderman, S., Winnerhed, S., & Hursti, T. J. (2016) · Computers in Human Behavior · doi:10.1016/j.chb.2016.01.035 · Cited by 25 · see citing works
Joseph, R. P., Dutton, G. R., Cherrington, A., Fontaine, K. R., Baskin, M. L., Casazza, K., Lorch, D., Allison, J. J., & Durant, N. H. (2015) · BMC Research Notes · doi:10.1186/s13104-015-1159-z · Cited by 24 · see citing works
Mañanes, G., & Vallejo, M. Á. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3091 · Cited by 23 · see citing works
Grossert, A., Urech, C., Alder, J., Gaab, J., Berger, T., & Hess, V. (2016) · BMC Cancer · doi:10.1186/s12885-016-2866-0 · Cited by 21 · see citing works
McCabe, M. P., & Price, E. (2009) · Journal of Sex & Marital Therapy · doi:10.1080/00926230903065963 · Cited by 20 · see citing works
Beintner, I., Jacobi, C., & Taylor, C. B. (2014) · Internet Interventions · doi:10.1016/j.invent.2014.03.001 · Cited by 19 · see citing works
Graham, A. L., Cha, S., Cobb, N. K., Ye, F., NIAURA, R. S., & Mushro, A. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2880 · Cited by 18 · see citing works
Rodgers, R. F., Franko, D. L., Shiyko, M. P., Intille, S. S., Wilson, K., O’Carroll, D., Lovering, M. E., Matsumoto, A., Iannuccilli, A., Luk, S., et al. (2015) · Health Informatics Journal · doi:10.1177/1460458214565950 · Cited by 15 · see citing works
Blake, H., Quirk, H., Leighton, P. A., Randell, T. L., Greening, J. E., Guo, B., & Glazebrook, C. (2016) · Trials · doi:10.1186/s13063-016-1719-0 · Cited by 15 · see citing works
Carolan, S., Harris, P. R., Greenwood, K., & Cavanagh, K. (2016) · Trials · doi:10.1186/s13063-016-1733-2 · Cited by 9 · cited 3× · see citing works
“In 23 studies, the intended usage was described as well (Category B operationalization) [51-73], and 5 studies reported the intended usage with a justification for this threshold (Category C operationalization) [74-78].”
BackgroundMertens, A., Becker, S., Theis, S., Rasche, P., Wille, M., Bröhl, C., Finken, L., & Schlick, C. (2017) · Advances in Intelligent Systems and Computing · doi:10.1007/978-3-319-41652-6_28 · Cited by 5 · see citing works
Flagged first, then by citations
1 of the 84 references couldn’t be matched to a known paper.
Research works printed but not linked: 4
- SmithWPlodererBWadleyGWebberSBorlandRTrajectories of Engagement and Disengagement with a Story-Based Smoking Cessation App20172017 CHI Conference on Human Factors in Computing SystemsMay 6-11, 2017Denver, ColoradoACM304556
- Batterham, PJ, 2008, Patient Prefer Adherence, 2, 97
- An, LC, 2006, Nicotine Tob Res, 8, S7
- Wangberg, SC, 2008, Patient Prefer Adherence, 2, 57
Cited by
Sorted by citations
Jakob, R., Harperink, S., Rudolf, A. M., Fleisch, E., Haug, S., Mair, J. L., Salamanca-Sanabria, A., & Kowatsch, T. (2022) · Journal of Medical Internet Research · doi:10.2196/35371 · Cited by 446 · see citing works
Short, C. E., DeSmet, A., Woods, C., Williams, S. L., Maher, C., Middelweerd, A., Müller, A. M., Wark, P. A., Vandelanotte, C., Poppe, L., et al. (2018) · Journal of Medical Internet Research · doi:10.2196/jmir.9397 · Cited by 400 · see citing works
Digital interventions for the treatment of depression: a meta-analytic review
Moshe, I., Terhorst, Y., Philippi, P., Domhardt, M., Cuijpers, P., Cristea, I., Pulkki-Råback, L., Baumeister, H., & Sander, L. B. (2021) · Psychological Bulletin · doi:10.1037/bul0000334 · Cited by 390 · see citing works
Simblett, S., Greer, B., Matcham, F., Curtis, H., Polhemus, A., Ferrão, J., Gamble, P., & Wykes, T. (2018) · Journal of Medical Internet Research · doi:10.2196/10480 · Cited by 270 · see citing works
Hauser-Ulrich, S., Künzli, H., Meier-Peterhans, D., & Kowatsch, T. (2020) · JMIR mHealth and uHealth · doi:10.2196/15806 · Cited by 210 · see citing works
Kelders, S. M., van Zyl, L. E., & Ludden, G. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.00926 · Cited by 207 · see citing works
Self-citationPatel, M. L., Wakayama, L. N., & Bennett, G. G. (2021) · Obesity · doi:10.1002/oby.23088 · Cited by 206 · see citing works
Warrington, L., Absolom, K. L., Conner, M. T., Kellar, I., Clayton, B., Ayres, M., & Velikova, G. (2018) · Journal of Medical Internet Research · doi:10.2196/10875 · Cited by 200 · see citing works
Sommers-Spijkerman, M., Austin, J., Bohlmeijer, E., & Pots, W. (2021) · JMIR Mental Health · doi:10.2196/28168 · Cited by 179 · see citing works
Richards, D., Enrique, A., Eilert, N., Franklin, M., Palacios, J., Duffy, D., Earley, C., Chapman, J., Jell, G., Sollesse, S., et al. (2020) · npj Digital Medicine · doi:10.1038/s41746-020-0293-8 · Cited by 154 · see citing works
Asbjørnsen, R. A., Smedsrød, M. L., Solberg Nes, L., Wentzel, J., Varsi, C., Hjelmesæth, J., & van Gemert-Pijnen, J. E. (2019) · Journal of Medical Internet Research · doi:10.2196/14265 · Cited by 150 · see citing works
Pham, Q., Graham, G., Carrion, C., Morita, P. P., Seto, E., Stinson, J. N., & Cafazzo, J. A. (2019) · JMIR mHealth and uHealth · doi:10.2196/11941 · Cited by 131 · see citing works
Challenges and solutions for N-of-1 design studies in health psychology
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Crafoord, M.-T., Fjell, M., Sundberg, K. K., Nilsson, M. I., & Langius‐Eklöf, A. (2020) · Journal of Medical Internet Research · doi:10.2196/17058 · Cited by 114 · see citing works
Kelders, S. M., Sommers‐Spijkerman, M., & Goldberg, J. M. (2018) · Journal of Medical Internet Research · doi:10.2196/jmir.9923 · Cited by 113 · see citing works
Self-citationWare, P., Dorai, M., Ross, H. J., Cafazzo, J. A., Laporte, A., Boodoo, C., & Seto, E. (2019) · JMIR mhealth and uhealth · doi:10.2196/13259 · Cited by 95 · see citing works
Forbes, A., Keleher, M. R., Venditto, M., & DiBiasi, F. (2023) · Journal of Medical Internet Research · doi:10.2196/43727 · Cited by 94 · see citing works
Leung, C., Pei, J., Hudec, K., Shams, F., Munthali, R., & Vigo, D. (2022) · Journal of Medical Internet Research · doi:10.2196/36004 · Cited by 94 · see citing works
Enrique, A., Palacios, J. E., Ryan, H., & Richards, D. (2019) · Journal of Medical Internet Research · doi:10.2196/12775 · Cited by 81 · see citing works
Beintner, I., Vollert, B., Zarski, A.-C., Bolinski, F., Musiat, P., Görlich, D., Ebert, D. D., & Jacobi, C. (2019) · Journal of Medical Internet Research · doi:10.2196/14181 · Cited by 89 · see citing works
Kelders, S. M., Kip, H., & Greeff, J. (2020) · Journal of Medical Internet Research · doi:10.2196/17757 · Cited by 88 · see citing works
Self-citationAsbjørnsen, R. A., Wentzel, J., Smedsrød, M. L., Hjelmesæth, J., Clark, M. M., Solberg Nes, L., & Van Gemert-Pijnen, J. E. W. C. (2020) · Journal of Medical Internet Research · doi:10.2196/22598 · Cited by 84 · see citing works
Salamanca-Sanabria, A., Richards, D., Timulak, L., Connell, S., Mojica Perilla, M., Parra-Villa, Y., & Castro-Camacho, L. (2020) · JMIR Mental Health · doi:10.2196/13392 · Cited by 83 · see citing works
Patients’ Needs and Requirements for eHealth Pain Management Interventions: Qualitative Study
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Achilles, M. R., Anderson, M., Li, S., Subotic-Kerry, M., Parker, B., & O’Dea, B. (2020) · Digital Health · doi:10.1177/2055207620926064 · Cited by 77 · see citing works
Arsenijevic, J., Tummers, L. G., & Bosma, N. S. (2019) · Journal of Medical Internet Research · doi:10.2196/11613 · Cited by 75 · see citing works
Winter, N., Russell, L., Ugalde, A., WHITE, V. M., & Livingston, P. M. (2022) · Journal of Medical Internet Research · doi:10.2196/30026 · Cited by 80 · see citing works
Perski, O., BLANDFORD, A. E., Garnett, C. V., Crane, D., West, R., & Michie, S. (2019) · Translational Behavioral Medicine · doi:10.1093/tbm/ibz039 · Cited by 70 · see citing works
Hardy, A., Wojdecka, A. B., West, J., Matthews, E., Golby, C., Ward, T., Lopez, N. D., Freeman, D. H., Waller, H., Kuipers, E., et al. (2018) · JMIR Mental Health · doi:10.2196/11222 · Cited by 72 · see citing works
Loeckx, M., Rabinovich, R., Demeyer, H., Louvaris, Z., Tanner, R., Rubio, N., Frei, A. L., de Jong, C., Gimeno‐Santos, E., Rodrigues, F. M. M., et al. (2018) · JMIR mhealth and uhealth · doi:10.2196/mhealth.9774 · Cited by 72 · see citing works
Engagement and attrition in digital mental health: current challenges and potential solutions
Smith, K., Ward, T., Lambe, S., Ostinelli, E. G., Blease, C., Gant, T., Gold, S. M., Holmes, E. A., Paccoud, I., Vinnikova, A., et al. (2025) · npj Digital Medicine · doi:10.1038/s41746-025-01778-w · Cited by 71 · see citing works
Miller, S., Ainsworth, B., Yardley, L., Milton, A., Weal, M. J., Smith, P. W. F., & Morrison, L. G. (2018) · Journal of Medical Internet Research · doi:10.2196/10966 · Cited by 66 · see citing works
Tighe, S. A., Ball, K., Kensing, F., Kayser, L., Rawstorn, J. C., & Maddison, R. (2020) · Journal of Medical Internet Research · doi:10.2196/16774 · Cited by 68 · see citing works
Jabir, A. I., Martinengo, L., Lin, X., Torous, J., Subramaniam, M., & Tudor Car, L. (2023) · Journal of Medical Internet Research · doi:10.2196/44548 · Cited by 63 · see citing works
“Systematic reviews on user adherence and engagement to DHIs also strongly suggested a more unified operationalization of engagement measures and their relationship with other subjectively reported outcomes [10,56].”
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Daniore, P., Nittas, V., & von Wyl, V. (2022) · Journal of Medical Internet Research · doi:10.2196/39910 · Cited by 60 · see citing works
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Stubberud, A., & Linde, M. (2018) · Current Pain and Headache Reports · doi:10.1007/s11916-018-0718-0 · Cited by 49 · see citing works
van de Graaf, D. L., Trompetter, H. R., Smeets, T., & Mols, F. (2021) · Internet Interventions · doi:10.1016/j.invent.2021.100465 · Cited by 49 · see citing works
A pilot evaluation of a smartphone application for workplace depression
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“Further investigation is required to determine the minimum intervention dosage required to achieve positive change, in order to operationalise “adherence” to the Anchored intervention [43].”
BackgroundEvaluating Patient-Centered Mobile Health Technologies: Definitions, Methodologies, and Outcomes
Bruce, C. R., Harrison, P., Giammattei, C., Desai, S.-N., Sol, J. R., Jones, S. L., & Schwartz, R. L. (2020) · JMIR mhealth and uhealth · doi:10.2196/17577 · Cited by 42 · see citing works
Wiegel, J., Seppen, B. F., van der Leeden, M., van der Esch, M., de Vries, R., & Bos, W. H. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph181910161 · Cited by 43 · see citing works
Lappalainen, P., Lappalainen, R., Keinonen, K., Kaipainen, K., Puolakanaho, A., Muotka, J., & Kiuru, N. (2023) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2022.12.001 · Cited by 41 · see citing works
Adhärenz digitaler Interventionen im Gesundheitswesen: Definitionen, Methoden und offene Fragen
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Radomski, A. D., Wozney, L., McGrath, P., Huguet, A., Hartling, L., Dyson, M. P., Bennett, K., & Newton, A. S. (2019) · Journal of Medical Internet Research · doi:10.2196/11128 · Cited by 40 · see citing works
“Adoption of a recent standardized definition and calculation of adherence [118] can clarify what is meant by specific program use terms and allow for comparisons of outcomes across programs. iCBT programs’ widespread implementation and ability to meet the health goals of users will involve an…”
BackgroundMorgiève, M., Genty, C., Azé, J., Dubois, J., Leboyer, M., Vaïva, G., Berrouiguet, S., & Courtet, P. (2020) · JMIR mhealth and uhealth · doi:10.2196/15741 · Cited by 40 · see citing works
Kip, H., Jong, N. B.-D., van Gemert‐Pijnen, J. E. W. C., & Kelders, S. M. (2024) · Journal of Medical Internet Research · doi:10.2196/59601 · Cited by 41 · see citing works
Self-citationUlrich, S., Gantenbein, A. R., Zuber, V., Von Wyl, A., Kowatsch, T., & Künzli, H. (2024) · Journal of Medical Internet Research · doi:10.2196/50132 · Cited by 36 · see citing works
“This procedure offers flexibility in line with the recommended mHealth intervention strategies [82,83] and is similar to the dose-response rate in pharmaceutical research, where medication dosage can vary depending on the patient’s condition and characteristics.”
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Melchiorre, M. G., Lamura, G., & Barbabella, F. (2018) · PLoS ONE · doi:10.1371/journal.pone.0207292 · Cited by 35 · see citing works
The peril of self-reported adherence in digital interventions: A brief example
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Dissemination Strategies for mHealth Apps: Systematic Review
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Sanatkar, S., Baldwin, P. A., Huckvale, K., Clarke, J., Christensen, H. M., Harvey, S. B., & Proudfoot, J. G. (2019) · Journal of Medical Internet Research · doi:10.2196/14728 · Cited by 35 · see citing works
Hermosa, J. L. R., Gomila, A. F., Puente‐Maestu, L., Diago, C. A. A., González, F. J. C., de Molina, R. M., Fuentes, M. E., Álvarez-Sala, J. L., & Rubio, M. C. (2020) · JMIR mhealth and uhealth · doi:10.2196/15699 · Cited by 36 · see citing works
Digital stress management in cancer: testing StressProffen in a 12-month randomized controlled trial
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Croon, R. D., Geuens, J., Verbert, K., & Abeele, V. V. (2021) · Lecture notes in computer science · doi:10.1007/978-3-030-77277-2_14 · Cited by 35 · see citing works
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Bostrøm, K., Børøsund, E., Varsi, C., Eide, H., Flakk Nordang, E., Schreurs, K. M., Waxenberg, L. B., Weiss, K. E., Morrison, E. J., Cvancarova Småstuen, M., et al. (2020) · JMIR Formative Research · doi:10.2196/23893 · Cited by 34 · see citing works
van Lotringen, C. M., Lusi, B., Westerhof, G. J., Ludden, G., Kip, H., Kelders, S. M., & Noordzij, M. L. (2023) · JMIR Mental Health · doi:10.2196/42403 · Cited by 34 · see citing works
Self-citationEşer, A. K., & Ayaz‐Alkaya, S. (2021) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2021.101969 · Cited by 33 · see citing works
Costa‐Brito, A. R., Bovolini, A., Rúa-Alonso, M., Vaz, C., Morán, J. F. O., Pagador, J. B., & Vila-Chã, C. J. F. (2023) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2023.105287 · Cited by 29 · see citing works
Adu, M. D., Malabu, U. H., Malau‐Aduli, A. E. O., Drovandi, A. D., & Malau‐Aduli, B. S. (2020) · JMIR mhealth and uhealth · doi:10.2196/17802 · Cited by 32 · see citing works
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Micaux, C., Wiklander, M., Eriksson, L. E., Wettergren, L., & Lampic, C. (2022) · JMIR Cancer · doi:10.2196/33239 · Cited by 31 · see citing works
Forman‐Hoffman, V. L., Flom, M., Mariano, T. Y., Chiauzzi, E. J., Williams, A. A. A., Kirvin-Quamme, A., Pajarito, S., Durden, E., & Perski, O. (2023) · Journal of Medical Internet Research · doi:10.2196/47198 · Cited by 36 · see citing works
Lifestyle interventions to maternal weight loss after birth: a systematic review
Christiansen, P. K., Skjøth, M. M., Rothmann, M. J., Vinter, C. A., Lamont, R., & Draborg, E. (2019) · Systematic Reviews · doi:10.1186/s13643-019-1186-2 · Cited by 31 · see citing works
Kahl, B. L., Miller, H. M., Cairns, K., Giniunas, H., & Nicholas, M. (2020) · JMIR Mental Health · doi:10.2196/21280 · Cited by 31 · see citing works
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Hardy, A., Ward, T., Emsley, R., Greenwood, K., Freeman, D. H., Fowler, D. G., Kuipers, E., Bebbington, P., & Garety, P. A. (2022) · JMIR Human Factors · doi:10.2196/29725 · Cited by 31 · see citing works
Montalescot, L., Baussard, L., & Charbonnier, É. (2024) · Journal of Medical Internet Research · doi:10.2196/52542 · Cited by 33 · see citing works
van der Hout, A., van Uden-Kraan, C. F., Holtmaat, K., Jansen, F., Lissenberg-Witte, B. I., Nieuwenhuijzen, G. A. P., Hardillo, J. A., Baatenburg de Jong, R. J., Tiren-Verbeet, N. L., Sommeijer, D. W., et al. (2021) · Internet Interventions · doi:10.1016/j.invent.2021.100429 · Cited by 29 · see citing works
Effectiveness trial of an online self-help intervention for sexual problems after cancer
Schover, L. R., Strollo, S., Stein, K., Fallon, E., & Smith, T. (2020) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2020.1762813 · Cited by 29 · see citing works
Lenhard, F., Mitsell, K., Jolstedt, M., Vigerland, S., Wahlund, T., Nord, M., Bjureberg, J., Sahlin, H., Andrén, P., Aspvall, K., et al. (2019) · Journal of Medical Internet Research · doi:10.2196/13602 · Cited by 30 · see citing works
Ramos, L. A., Blankers, M., van Wingen, G. A., de Bruijn, T., Pauws, S. C., & Goudriaan, A. E. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.734633 · Cited by 30 · see citing works
White, K. M., Williamson, C., Bergou, N., Oetzmann, C., de Angel, V., Matcham, F., Henderson, C., & Hotopf, M. H. (2022) · npj Digital Medicine · doi:10.1038/s41746-022-00624-7 · Cited by 30 · see citing works
Moshe, I., Terhorst, Y., Paganini, S., Schlicker, S., Pulkki-Råback, L., Baumeister, H., Sander, L. B., & Ebert, D. D. (2022) · Journal of Medical Internet Research · doi:10.2196/38261 · Cited by 28 · see citing works
“Finally, although dropout in this study was operationalized according to the usage intended by the clinicians who developed the intervention [76], it is important to highlight that it is not always necessary for patients to complete the full per-protocol treatment to benefit clinically [30].”
A systematic review and meta analysis on digital mental health interventions in inpatient settings
Diel, A., Schröter, I. C., Frewer, A.-L., Jansen, C., Robitzsch, A., Gradl-Dietsch, G., Teufel, M., & Bäuerle, A. (2024) · npj Digital Medicine · doi:10.1038/s41746-024-01252-z · Cited by 31 · see citing works
Graffigna, G., Bosio, C., Pagnini, F., Volpato, E., Previtali, E., Leone, S., D’Amico, F., Armuzzi, A., & Danese, S. (2021) · BMC Psychology · doi:10.1186/s40359-021-00692-6 · Cited by 28 · see citing works
Hanano, M., Rith-Najarian, L., Boyd, M., & Chavira, D. (2022) · JMIR Mental Health · doi:10.2196/30754 · Cited by 26 · see citing works
Lehmann, M., Jones, L., & Schirmann, F. (2024) · Journal of Medical Internet Research · doi:10.2196/45469 · Cited by 26 · see citing works
Sieverink, F., Kelders, S. M., Braakman‐Jansen, A., & van Gemert-Pijnen, J. (2019) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-019-0969-7 · Cited by 26 · see citing works
Self-citationRonteltap, A., Bukman, A. J., Nagelhout, G. E., Hermans, R. C. J., Hosper, K., Haveman‐Nies, A., Lupker, R., & Bolman, C. A. W. (2022) · BMC Nutrition · doi:10.1186/s40795-022-00635-3 · Cited by 28 · see citing works
Yeager, C. M., Shoji, K., Łuszczyńska, A., & Benight, C. C. (2018) · JMIR Mental Health · doi:10.2196/mental.9449 · Cited by 27 · see citing works
Murray, J., French, D., Patterson, C., Kee, F., Gough, A., Tang, J., & Hunter, R. F. (2019) · Journal of Medical Internet Research · doi:10.2196/11394 · Cited by 25 · see citing works
Hemmings, N. R., Kawadler, J. M., Whatmough, R., Ponzo, S., Rossi, A., Morelli, D., Bird, G., & Plans, D. (2021) · JMIR Formative Research · doi:10.2196/21737 · Cited by 19 · see citing works
“Consistent reporting of these variables remains an issue in the literature [38-40].”
BackgroundSchuster, R., Kalthoff, I., Walther, A., Köhldorfer, L., Partinger, E., Berger, T., & Laireiter, A.-R. (2019) · Journal of Medical Internet Research · doi:10.2196/11860 · Cited by 25 · see citing works
Jackson, H. M., Calear, A. L., Batterham, P. J., Ohan, J. L., Farmer, G. M., & Farrer, L. M. (2023) · Journal of Medical Internet Research · doi:10.2196/44673 · Cited by 25 · see citing works
Côté, J., Rouleau, G., Ramirez-Garcìa, P., Auger, P., Thomas, R., & Leblanc, J. (2020) · JMIR Public Health and Surveillance · doi:10.2196/17733 · Cited by 25 · see citing works
Wright, H., Martin, F., Clyne, W., Clark, C. C. T., Matouskova, G., McGillion, M. H., & Turner, A. (2021) · Journal of Medical Internet Research · doi:10.2196/28322 · Cited by 22 · see citing works
Almodóvar, A. S., Surve, S., Axon, D. R., Cooper, D., & Nahata, M. C. (2018) · JMIR mhealth and uhealth · doi:10.2196/mhealth.9612 · Cited by 25 · see citing works
Seewer, N., Skoko, A., Käll, A., Andersson, G., Luhmann, M., Berger, T., & Krieger, T. (2024) · Scientific Reports · doi:10.1038/s41598-024-57254-0 · Cited by 26 · see citing works
Understanding Adherence to Digital Health Technologies: Systematic Review of Predictive Factors
Figueiredo, T., Alcântara, L., Carrilho, J., Paúl, C., & Costa, E. M. (2025) · Journal of Medical Internet Research · doi:10.2196/77362 · Cited by 27 · see citing works
Vehı́, J., Isern, J. R., Parcerisas, A., Calm, R., & Contreras, I. (2019) · JMIR mhealth and uhealth · doi:10.2196/11933 · Cited by 24 · see citing works
Schuster, R., Laireiter, A., Berger, T., Moritz, S., Meyer, B., Hohagen, F., & Klein, J. P. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.05.122 · Cited by 22 · see citing works
Haug, S., Castro, R. P., Wenger, A., & Schaub, M. P. (2020) · BMC Public Health · doi:10.1186/s12889-020-09995-6 · Cited by 24 · see citing works
van de Wiel, H. J., Stuiver, M. M., May, A. M., van Grinsven, S., Aaronson, N. K., Oldenburg, H. S. A., van der Poel, H. G., Koole, S. N., Retèl, V. P., van Harten, W. H., et al. (2021) · Cancers · doi:10.3390/cancers13153665 · Cited by 25 · see citing works
Perski, O., Lumsden, J., Garnett, C. V., BLANDFORD, A. E., West, R., & Michie, S. (2019) · Journal of Medical Internet Research · doi:10.2196/16197 · Cited by 23 · see citing works
Zhu, H., Chen, X., Yang, J., Wu, Q., Zhu, J., & Chan, S. W. (2020) · JMIR mhealth and uhealth · doi:10.2196/18896 · Cited by 23 · see citing works
van der Kamp, M., Reimering Hartgerink, P., Driessen, J., Thio, B., Hermens, H., & Tabak, M. (2021) · JMIR Formative Research · doi:10.2196/24634 · Cited by 19 · see citing works
- Authors
- Sieverink, F., Kelders, S. M., & van Gemert-Pijnen, J. E.
- Affiliations
- University of Twente (NL)
- North-West University (ZA)
- Corresponding author
- Sieverink, Floor
- Venue
- Journal of Medical Internet Research
- Publisher
- JMIR Publications Inc.
- Published
- 2017-12-06
- Volume
- 19
- Issue
- 12
- Pages
- e402
- ISSN
- 1438-8871 (ISSN-L)
- PMC
- PMC5738543
- OpenAlex
- W2774320409
- Semantic Scholar
- a1db2bb515ffdc128b4290c1c2d3f04a5b280310
- Cited by
- 331
- References
- 84
- Citations by year
- 2026: 28 · 2025: 33 · 2024: 35 · 2023: 38 · 2022: 45 · 2021: 51 · 2020: 48 · 2019: 31 · 2018: 21 · 2017: 1
- FWCI
- 4.86
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Journal of Medical Internet Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- University of Twente Research Information (publishedVersion, cc-by)
- University of Twente Research Information (submittedVersion, cc-by)
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Keywords
- eHealth technologies, technology adherence, intended use, mental health technology, eHealth evaluation, operating mechanism
- MeSH terms
- Humans, Patient Compliance, Telemedicine, Biomedical Technology
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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