CoChat
Sign Up
Cited by 156Sleep and Wakefulness ResearchCircadian rhythm and melatoninNeuroscience of respiration and sleep

The interrelationship between sleep regulation and thermoregulation

Open access
Krauchi, Kurt·2010·Frontiers in bioscience
DOI 10.2741/3636
Open this paper in CoChat — free accountOpen PDF

Abstract

The circadian distribution of vigilance states and body temperature changes are tightly coupled. The increase in heat loss at the end of the day is associated with increased ease to fall asleep. Experimental data show that warming the skin or the brain can increase sleep propensity, sleep consolidation, and the duration of sleep. Anatomical and neurophysiological studies show that the pre-optic-anterior-hypothalamus (POAH) is the main integrator of sleep and thermoregulatory information. It integrates information on vigilance states, body temperature, and environmental temperature and influences vigilance states and body temperature in response. Animals that display daily torpor may be a valuable model to investigate the relationship between sleep and thermoregulation. During torpor these animals seem to apply similar strategies and physiological processes as humans during entrance into sleep, but in a more extreme way, providing an excellent opportunity to investigate these processes in more detail. More systematic investigations are needed to further our understanding of the relationship between sleep and thermoregulation, and may provide the basis to treat sleep disturbances with thermal strategies.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.2741/3636

Cites

187 of 187 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Thermoregulatory changes preceded by a melatonin rise are robust findings related to psychological cues of relaxation, not time-bound to the evening hours.

    “These thermoregulatory changes preceded by a melatonin rise are robust findings related to psychological cues of relaxation (e.g., supine body posture) [53,54] not time-bound to the evening hours, as they are also reported preceding an afternoon nap [31,53,55].”

    From Preliminary Results: The Impact of Smartphone Use and Short-Wavelength Light during the Evening on Circadian Rhythm, Sleep and Alertness (2021) · cites this paper as [54]

    Section 6.1 (page unavailable) describes robust thermoregulatory effects of relaxing behavior, including lying supine, and says similar changes occur before an afternoon nap. It does not say an afternoon nap is preceded by a melatonin rise. Section 4 instead describes nocturnal melatonin secretion and notes that endogenous melatonin levels are low in the afternoon. (LLM, conf=0.86)

    Experimental — accuracy not yet measured

  • The circadian rhythm of proximal skin temperature follows that of core body temperature.

    “The circadian rhythm of proximal skin temperature (e.g. forehead, thigh), on the other hand, follows that of core body temperature; the distal – proximal skin temperature gradient, therefore, is useful in determining body heat loss via the extremities [10].”

    From Temperature regulation in women: Effects of the menstrual cycle (2020) · cites this paper as [10]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

1 of the 188 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

  1. Hales, J. R. S.: Skin arteriovenous anastomoses, their control and role in thermoregulation. In: Cardiovascular Shunts. Alfred Benzon Symposium 21. Eds: K. Johansen&W. W. Burggren. Munksgaard, Copenhagen (1985)
  2. Horne, J.: Human slow-wave sleep: A review and appraisal of recent finding, with implications for sleep functions, and psychiatric illness. Experientia, 48, 941-954 (1992) 121.
  3. Malan, A.: pH as a control factor in hibernation. In: Living in the cold. Eds: H. C. Heller, X. J. Musacchia&L. C. H. Wang. Elsevier, New York (1986) 185.
  4. Fisher, K. C. & J. F. Manery: Water and electrolyte metabolism in heterotherms. In: Mammalian hibernation II. Eds: K. C. Fisher, A. R. Dawe, C. P. Lyman, E. Schonbaum&F. E. South. Elsevier, New York (1964) 211.

Cited by

Sorted by citations

Related

Authors
Krauchi, K.
Venue
Frontiers in bioscience
Publisher
IMR Press
Published
2010
Volume
15
Issue
1
Pages
604
ISSN
  • 1093-4715 (ISSN-L)
  • 1093-9946
DOI
10.2741/3636
OpenAlex
W2046753384
Cited by
156
References
188
Citations by year
2026: 18 · 2025: 15 · 2024: 8 · 2023: 7 · 2022: 9 · 2021: 18 · 2020: 8 · 2019: 11 · 2018: 9 · 2017: 7 · 2016: 10 · 2015: 9 · 2014: 6 · 2013: 10 · 2012: 4
FWCI
0.28
Type
journal article
Language
en
Open access
Locations
  • Frontiers in bioscience (publishedVersion)
  • PubMed (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Leiden Repository (Leiden University) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
Keywords
sleep regulation, thermoregulation, preoptic anterior hypothalamus, circadian rhythm, sleep-wake states, body temperature, sleep propensity, sleep consolidation, daily torpor, skin warming, sleep disorders
MeSH terms
Animals, Body Temperature, Body Temperature Regulation, Brain, Circadian Rhythm, Humans, Sleep, Sleep Wake Disorders, Sleep Stages, Temperature

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review