Cited by 48Probiotics and Fermented FoodsGut microbiota and healthMicrobial Metabolites in Food Biotechnology

Interactions between prebiotics, probiotics, polyunsaturated fatty acids and polyphenols: diet or supplementation for metabolic syndrome prevention?

Peluso, Ilaria, Romanelli, Luca, Palmery, Maura·2014·International Journal of Food Sciences and Nutrition

Abstract

The metabolic syndrome can be prevented by the Mediterranean diet, characterized by fiber, omega-3 polyunsaturated fatty acids and polyphenols. However, the composition of the Mediterranean diet, which can be viewed as a natural multiple supplement, is poorly controlled, and its beneficial effects poorly predictable. The metabolic syndrome is associated with intestinal dysbiosis and the gut microbioma seems to be the main target and player in the interactions occurring between probiotics, prebiotics, omega 3 polyunsaturated fatty acids, and polyphenols. From the reviewed evidence, it is reasonable to manage growth and metabolism of gut microflora with specific prebiotics and polyphenols. Even though the healthy properties of functional foods and nutraceuticals still need to be fully elucidated, available data suggest that well-designed supplements, containing the better ratio of omega-3 polyunsaturated fatty acids and antioxidants, specific probiotic strains, and selected polyphenols and prebiotics, could be useful in metabolic syndrome prevention and treatment.

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Crossref · 10.3109/09637486.2014.880670

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Authors
Peluso, I., Romanelli, L., & Palmery, M.
Affiliations
Sapienza University of Rome (IT)
Corresponding author
Palmery, Maura
Venue
International Journal of Food Sciences and Nutrition
Published
2014-01-28
Volume
65
Issue
3
Pages
259-267
ISSN
  • 0963-7486 (ISSN-L)
  • 1465-3478
OpenAlex
W2019340711
Cited by
48
References
136
Citations by year
2026: 3 · 2025: 2 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 6 · 2020: 5 · 2019: 3 · 2018: 6 · 2017: 8 · 2016: 2 · 2015: 6 · 2013: 1
FWCI
7.65
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Food Sciences and Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
Keywords
metabolic syndrome, prebiotics, probiotics, omega-3 polyunsaturated fatty acids, polyphenols, Mediterranean diet, gut microbiota, gut dysbiosis, nutraceuticals, functional foods, dietary supplementation, antioxidants
MeSH terms
Diet, Humans, Intestines, Fatty Acids, Omega-3, Dietary Supplements, Probiotics, Metabolic Syndrome, Prebiotics, Polyphenols, Microbiota, Dysbiosis

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