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Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study

Open access
Gabel, Kelsey, Hoddy, Kristin K., Haggerty, Nicole, Song, Jeehee, Kroeger, Cynthia M., Trepanowski, John F., Panda, Satchidananda, Varady, Krista A.·2018·Nutrition and Healthy Aging

Abstract

BACKGROUND: Time restricted feeding decreases energy intake without calorie counting and may be a viable option for weight loss. However, the effect of this diet on body weight in obese subjects has never been examined. OBJECTIVE: This study investigated the effects of 8-h time restricted feeding on body weight and metabolic disease risk factors in obese adults. DESIGN: Obese subjects ( n = 23) participated in an 8-h time restricted feeding intervention (ad libitum feeding between 10:00 to 18:00 h, water fasting between 18:00 to 10:00 h) for 12 weeks. Weight loss and other outcomes were compared to a matched historical control group ( n = 23). RESULTS: Body weight and energy intake decreased in the time restricted group (–2.6% ± 0.5; –341 ± 53 kcal/d) relative to controls over 12 weeks ( P < 0.05). Systolic blood pressure decreased in the time restricted feeding group (–7 ± 2 mm Hg) versus controls ( P < 0.05). Fat mass, lean mass, visceral fat mass, diastolic blood pressure, LDL cholesterol, HDL cholesterol, triglycerides, fasting glucose, fasting insulin, HOMA-IR, and homocysteine were not significantly different from controls after 12 weeks (no group×time interaction). CONCLUSION: These findings suggest that 8-h time restricted feeding produces mild caloric restriction and weight loss, without calorie counting. It may also offer clinical benefits by reducing blood pressure.

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Crossref · 10.3233/nha-170036

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Metadata

Authors
Gabel, K., Hoddy, K. K., Haggerty, N., Song, J., Kroeger, C. M., Trepanowski, J. F., Panda, S., & Varady, K. A.
Venue
Nutrition and Healthy Aging
Published
2018-05-11
Volume
4
Issue
4
Pages
345-353
ISSN
  • 2451-9480 (ISSN-L)
  • 2451-9502
OpenAlex
W2799962683
Cited by
626
References
13
FWCI
36.97
Type
journal article
Language
en
Open access
hybrid

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