Fucoidans from Brown Alga Fucus evanescens: Structure and Biological Activity
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Brown alga Fucus evanescens, widespread in the Far Eastern seas of Russia, is valuable source of sulfated polysaccharides – fucoidans with beneficial biological activities. The most homogenous fraction of fucoidan from F. evanescens was shown to be molecule containing linear main chain of alternating 2-sulfated 1,3- and 1,4-linked α-L-fucose residues. Few sulfate groups were found in position 4 of some 1,3-linked fucose residues. Acetyl groups occupied free C-3 of 1,4-linked residues and/or the C-4 of 1,3-linked fucose residues. Enzymatic hydrolysis, mild acid hydrolysis and autohydrolysis of native fucoidan were used for elucidation of the fine structural characteristics of fucoidan from F. evanescens. The aim of this review to summarize published data on biological activities of fucoidan from F. evanescens: antiviral, anticoagulant, thrombolytic, hepatoprotective, immunomodulatory, anticancer, and their practical application.
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Many compounds from macroalgae have antiinflammatory, antimutagenic, antitumor, antidiabetic, hepatoprotective, free radical scavenger, anticoagulant, thrombolytic, and antihypertensive properties.
“Many of these compounds have well-established antiinflammatory, antimutagenic, antitumor, antidiabetic, hepatoprotective, free radical scavengers, anticoagulants, thrombolytic, and antihyperthensive properties [108,109].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [109]
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The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value
Gomez-Zavaglia, A., Prieto Lage, M. A., Jimenez-Lopez, C., Mejuto, J. C., & Simal-Gandara, J. (2019) · Antioxidants · doi:10.3390/antiox8090406 · Cited by 280 · see citing works
- Authors
- Menshova, R. V., Shevchenko, N. M., Imbs, T. I., Zvyagintseva, T. N., Malyarenko, O. S., Zaporoshets, T. S., Besednova, N. N., & Ermakova, S. P.
- Affiliations
- Russian Academy of Sciences (RU)
- Corresponding author
- Ermakova, Svetlana P.
- Venue
- Frontiers in Marine Science
- Publisher
- Frontiers Media SA
- Published
- 2016-08-03
- Volume
- 3
- ISSN
- 2296-7745 (ISSN-L)
- OpenAlex
- W2484612807
- Cited by
- 85
- References
- 64
- Citations by year
- 2026: 3 · 2025: 10 · 2024: 5 · 2023: 14 · 2022: 8 · 2021: 13 · 2020: 20 · 2019: 6 · 2018: 1 · 2017: 5
- FWCI
- 5.78
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Marine Science (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Russian Foundation for Basic Research (15-04-01004, 16-54-540004)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- fucoidan, Fucus evanescens, sulfated polysaccharides, brown algae, polysaccharide structure, antiviral activity, anticoagulant activity, thrombolytic activity, hepatoprotection, immunomodulatory activity, anticancer activity, marine natural products
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