Cited by 48Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMind wandering and attentionMental Health Research Topics

Rumination as a Transdiagnostic Phenomenon in the 21st Century: The Flow Model of Rumination

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Wong, Stephanie M. Y., Chen, Eric Y. H., Lee, Michelle C. Y., Suen, Y. N., Hui, Christy L. M.·2023·Brain Sciences

Abstract

Rumination and its related mental phenomena share associated impairments in cognition, such as executive functions and attentional processes across different clinical conditions (e.g., in psychotic disorders). In recent decades, however, the notion of rumination has been increasingly narrowed to the “self-focused” type in depressive disorders. A closer review of the literature shows that rumination may be construed as a broader process characterized by repetitive thoughts about certain mental contents that interfere with one’s daily activities, not only limited to those related to “self”. A further examination of the construct of rumination beyond the narrowly focused depressive rumination would help expand intervention opportunities for mental disorders in today’s context. We first review the development of the clinical construct of rumination with regard to its historical roots and its roles in psychopathology. This builds the foundation for the introduction of the “Flow Model of Rumination (FMR)”, which conceptualizes rumination as a disruption of a smooth flow of mental contents in conscious experience that depends on the coordinated interactions between intention, memory, affect, and external events. The conceptual review concludes with a discussion of the impact of rapid technological advances (such as smartphones) on rumination. Particularly in contemporary societies today, a broader consideration of rumination not only from a cognition viewpoint, but also incorporating a human–device interaction perspective, is necessitated. The implications of the FMR in contemporary mental health practice are discussed.

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Crossref · 10.3390/brainsci13071041

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  • Perseverative cognitive processes such as worry and rumination are linked to extended cortisol activation.

    “This bidirectional relationship has been demonstrated in multiple studies, with perseverative cognitive processes such as worry and rumination linked to extended cortisol activation [28].”

    From Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice. (2026) · cites this paper as [28]

    Section 2.2.3 discusses stress-reactive rumination and depressive symptoms, while Section 2.2.5 discusses neural mechanisms of perseveration. Neither addresses cortisol activation. Searches for cortisol activation, the HPA axis, and prolonged endocrine responses found no passage linking worry or rumination to extended cortisol activation. (LLM, conf=0.72)

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  • The interaction between HPA axis activity and cognitive arousal is bidirectional: rising cortisol amplifies cognitive arousal, and heightened cognitive arousal increases cortisol levels.

    “The interaction between HPA axis activity and cognitive arousal is bidirectional: rising cortisol amplifies cognitive arousal, and heightened cognitive arousal in turn increases cortisol levels, creating a self-perpetuating cycle of anxiety and sleep disturbance.”

    From Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice. (2026) · cites this paper as [28]

    Section 3.2 discusses how affect and attention can perpetuate ruminative thoughts, but it does not address cortisol or HPA-axis activity. Searches for “HPA axis,” “cortisol,” and their interaction with cognitive arousal found no passage supporting the claimed bidirectional mechanism or its proposed link to sleep disturbance. (LLM, conf=0.76)

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Research works printed but not linked: 7

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  6. [40]Clark D.M. Wells A. A cognitive model of social phobia Social Phobia: Diagnosis, Assessment, and Treatment Heimberg R.G. Liebowitz M.R. Hope D.A. Schneier F.R. Guilford Press New York, NY, USA 1995 69 91
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Authors
Wong, S. M. Y., Chen, E. Y. H., Lee, M. C. Y., Suen, Y. N., & Hui, C. L. M.
Affiliations
University of Hong Kong (HK)
Corresponding author
Chen, Eric Y. H.
Venue
Brain Sciences
Publisher
MDPI AG
Published
2023-07-08
Volume
13
Issue
7
Pages
1041
ISSN
2076-3425 (ISSN-L)
OpenAlex
W4383817969
Cited by
48
References
186
Citations by year
2026: 14 · 2025: 25 · 2024: 8 · 2023: 1
FWCI
2.03
Type
journal article
Language
en
Open access
Locations
  • Brain Sciences (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Keywords
rumination, transdiagnostic mechanisms, depressive rumination, executive function, attention, psychosis, smartphone use, human-device interaction, mental health interventions

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