Rumination as a Transdiagnostic Phenomenon in the 21st Century: The Flow Model of Rumination
Open accessAbstract
Rumination and its related mental phenomena share associated impairments in cognition, such as executive functions and attentional processes across different clinical conditions (e.g., in psychotic disorders). In recent decades, however, the notion of rumination has been increasingly narrowed to the “self-focused” type in depressive disorders. A closer review of the literature shows that rumination may be construed as a broader process characterized by repetitive thoughts about certain mental contents that interfere with one’s daily activities, not only limited to those related to “self”. A further examination of the construct of rumination beyond the narrowly focused depressive rumination would help expand intervention opportunities for mental disorders in today’s context. We first review the development of the clinical construct of rumination with regard to its historical roots and its roles in psychopathology. This builds the foundation for the introduction of the “Flow Model of Rumination (FMR)”, which conceptualizes rumination as a disruption of a smooth flow of mental contents in conscious experience that depends on the coordinated interactions between intention, memory, affect, and external events. The conceptual review concludes with a discussion of the impact of rapid technological advances (such as smartphones) on rumination. Particularly in contemporary societies today, a broader consideration of rumination not only from a cognition viewpoint, but also incorporating a human–device interaction perspective, is necessitated. The implications of the FMR in contemporary mental health practice are discussed.
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Perseverative cognitive processes such as worry and rumination are linked to extended cortisol activation.
“This bidirectional relationship has been demonstrated in multiple studies, with perseverative cognitive processes such as worry and rumination linked to extended cortisol activation [28].”
From Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice. (2026) · cites this paper as [28]
Section 2.2.3 discusses stress-reactive rumination and depressive symptoms, while Section 2.2.5 discusses neural mechanisms of perseveration. Neither addresses cortisol activation. Searches for cortisol activation, the HPA axis, and prolonged endocrine responses found no passage linking worry or rumination to extended cortisol activation. (LLM, conf=0.72)
Experimental — accuracy not yet measuredThe interaction between HPA axis activity and cognitive arousal is bidirectional: rising cortisol amplifies cognitive arousal, and heightened cognitive arousal increases cortisol levels.
“The interaction between HPA axis activity and cognitive arousal is bidirectional: rising cortisol amplifies cognitive arousal, and heightened cognitive arousal in turn increases cortisol levels, creating a self-perpetuating cycle of anxiety and sleep disturbance.”
From Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice. (2026) · cites this paper as [28]
Section 3.2 discusses how affect and attention can perpetuate ruminative thoughts, but it does not address cortisol or HPA-axis activity. Searches for “HPA axis,” “cortisol,” and their interaction with cognitive arousal found no passage supporting the claimed bidirectional mechanism or its proposed link to sleep disturbance. (LLM, conf=0.76)
Experimental — accuracy not yet measured
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Effects of antipsychotics on rumination in patients with first-episode psychosis.
Lee, Y., Kang, N.-I., Lee, K.-H., Piao, Y.-H., Cui, Y., Kim, S.-W., Lee, B., Kim, J. J., Yu, J.-C., Lee, K. Y., et al. (2020) · Progress in Neuro-psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.109983 · Cited by 6 · see citing works
Ricarte, J. J., Ros, L., Latorre, J. M., & Barry, T. J. (2020) · PLoS ONE · doi:10.1371/journal.pone.0235378 · Cited by 6 · see citing works
Selective Attention to Threat is Specific to Delusions in First-Episode Psychosis
Bendall, S., Lim, M. H., Álvarez‐Jiménez, M., Hulbert, C. A., McGorry, P. D., & Jackson, H. J. (2014) · Journal of Experimental Psychopathology · doi:10.5127/jep.034613 · Cited by 4 · see citing works
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Cited by
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Le, G. H., Wong, S., Au, H. C. T., Badulescu, S., Gill, H., Vasudeva, S., Teopiz, K. M., Rhee, T. G., Ho, R., Kwan, A. T. H., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.09.118 · Cited by 36 · see citing works
Self-citationGlimpse on 21st century new phobias; a predictive model of nomophobia
Ceobanu, C., Marian, A., & Apostolache, R. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1252099 · Cited by 30 · see citing works
Research progress on the neural circuits mechanisms of anxiety
Gong, W. (2025) · Frontiers in Neural Circuits · doi:10.3389/fncir.2025.1609145 · Cited by 13 · see citing works
“However, translating preclinical findings faces unique challenges due to the complexity of human cognitive processes, such as rumination, which engage cortical circuits underrepresented in rodent models (Wong et al., 2023).”
López-Montón, M., Aonso-Diego, G., & Estévez, A. (2024) · Behavioral Science · doi:10.3390/bs14070580 · Cited by 13 · see citing works
“These findings are consistent with previous studies showing that rumination [76] and catastrophizing [77] are transdiagnostic variables observed in multiple psychopathologies, such as post-traumatic stress disorder, obsessive-compulsive disorder, anxiety disorders, depressive disorders, and body…”
ResultDERELİOĞLU, M., Vural, M., ÇİMEN, E., SAKİ, Ü., Saraçoğlu, Y. Y., Karataş, B., SAÇ, A., Yamaner, E., Halmatov, M., Yılmaz, C., et al. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1665882 · Cited by 11 · see citing works
Fazio, L., Raio, A., Banaschewski, T., Bokde, A. L. W., Desriviéres, S., Flor, H., Garavan, H., Gowland, P., Grigis, A., Heinz, A., et al. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1434470 · Cited by 11 · see citing works
The Potential of Wearable Sensors for Detecting Cognitive Rumination: A Scoping Review
Arnold, V. X., & Young, S. D. (2025) · Sensors · doi:10.3390/s25030654 · Cited by 9 · see citing works
“…significant given that rumination manifests as a transdiagnostic symptom across mental health conditions, including depression, generalized anxiety, post-traumatic stress disorder, social anxiety disorder, obsessive–compulsive disorder, bipolar disorder, and psychosis spectrum disorder [7,29–33].”
Scaffolded Rumination: The Case of Problematic Smartphone Use
Rovetta, F. F. (2024) · Topoi · doi:10.1007/s11245-024-10140-w · Cited by 7 · see citing works
Hasani, M., Zenoozian, S., Ahmadi, R., Khakpoor, S., Saberi, S., Pirzeh, R., & Saed, O. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07065-y · Cited by 8 · see citing works
Levinson, C. A., Kapadia, A., Sandoval-Araujo, L. E., Vanzhula, I. A., & Machry, K. (2025) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-081423-020831 · Cited by 6 · see citing works
Cotton, S., Menssink, J. M., Rickwood, D., Filia, K., Watson, A., Hasty, M. K., Herrman, H., Parker, A. G., Hetrick, S. E., Hickie, I. B., et al. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.120188 · Cited by 5 · see citing works
Imperatori, C., Rossi, E. D., Allegrini, G., Carbone, G. A., Benvenuti, S. M., Adenzato, M., Dell’Acqua, C., Presti, A. L., Ardito, R. B., & Farina, B. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.120535 · Cited by 5 · see citing works
“…a transdiagnostic process involved in the development and maintenance of psychopathology in both clinical and non-clinical individuals (Cano-L ´ opez et al., 2022; Clancy et al., 2020; Ehring, 2021; Grierson et al., 2016; Luca, 2019; Rood et al., 2009; Snyder et al., 2019; Wong et al., 2023).”
Zou, H.-Y., Ma, X.-H., Li, X., & Zhang, W. (2025) · International Journal of Cognitive Behavioral Therapy · doi:10.1007/s41811-025-00252-5 · Cited by 8 · see citing works
“The relationship between them may exhibit a cumulative effect of symptoms (Wong et al., 2023).”
Zhong, X. B., Li, S., & Zhou, W. (2025) · Acta Psychologica · doi:10.1016/j.actpsy.2025.105272 · Cited by 4 · see citing works
Şentürk, E., Geniş, B., Zorbozan, E., & Selcan, A. (2024) · Medical Bulletin of Haseki · doi:10.4274/haseki.galenos.2024.9393 · Cited by 4 · see citing works
“Rumination, defined as repetitive thinking about one’s feelings and concerns, contributes to distorted thoughts and unhealthy coping mechanisms that reinforce overshining patterns (29).”
BackgroundWoodyatt, L., de Vel‐Palumbo, M., Barron, A., Harous, C., Wenzel, M., & de Silva, S. (2025) · Self and Identity · doi:10.1080/15298868.2025.2513878 · Cited by 4 · see citing works
“2008; Luca, 2019; S. M. Wong et al., 2023).”
Aydın, E. F., Özcan, H., Yılmaz, S., Aşkın, S., Laçin, T. K., & Donbaloğlu, E. N. (2024) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2024.2347633 · Cited by 4 · see citing works
Guo, Y., Xiong, Q., Tan, Y., Zhao, J., Liu, S., Jia, J., Zhang, Z., Zhang, Y., & Ren, Z. (2025) · Psychological Medicine · doi:10.1017/s0033291725101505 · Cited by 3 · see citing works
Wong, S. M. Y., Choi, O., Suen, Y. N., Hui, C. L. M., Lee, E. H. M., Chan, S. K. W., & Chen, E. Y. H. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1574119 · Cited by 3 · see citing works
Self-citationLiu, J., Chen, T., Cui, J., Lai, W., Zhang, Q., Ye, J., Yang, T., Wang, Y., & Chan, R. C. K. (2024) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2024.104083 · Cited by 3 · see citing works
Tran, T., & Liu, Q. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.02.029 · Cited by 2 · see citing works
Li, J. H., Qiu, L. S., Wong, J., Lau, W., Bryant, R. A., Lies, J., Liddell, B. J., & Jobson, L. (2025) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2025.100924 · Cited by 2 · see citing works
Latent profile analysis of rumination subtypes and associations with suicidal ideation and behavior
Ha, H., & Shim, E. (2025) · Death Studies · doi:10.1080/07481187.2025.2591318 · Cited by 2 · see citing works
Chu, J., Yang, Y., & Wu, J. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1815526 · Cited by 2 · see citing works
“Emotional rumination refers to the reflection and in-depth thinking of past negative experiences, which makes individuals indulge in a vicious circle of negative emotional processing (Wong et al., 2023).”
Wong, S. M. Y., So, M. M., Suen, Y. N., Hui, C. L. M., & Chen, E. Y. H. (2025) · International Journal of Environmental Health Research · doi:10.1080/09603123.2025.2455991 · Cited by 2 · see citing works
Self-citationSo, M. M., Wong, S. M. Y., Hui, C. L. M., Suen, Y. N., Chan, S. K. W., Lee, E. H. M., & Chen, E. Y. H. (2025) · Journal of Loss and Trauma · doi:10.1080/15325024.2025.2493954 · Cited by 1 · see citing works
“…including depression and anxiety, as well as PTSD, are characterized by heightened stress reactivity, excessive attention toward the self and the traumatic event, and difficulties in emotion regulation (Badour & Feldner, 2013; Clark et al., 1994; Nolen-Hoeksema & Morrow, 1991; Wong et al., 2023).”
InfluentialSelf-citationBavi, S., Salar, A. R., Talayeri, A., & Bahmaei, H. (2025) · Journal of Contemporary Psychotherapy · doi:10.1007/s10879-025-09676-8 · Cited by 1 · see citing works
“These thoughts hinder adaptive problem-solving and exacerbate negative thoughts in obsessive-compulsive disorder patients (Wong et al., 2023).”
Asadi, H., Kivi, H. G., & Samarein, Z. A. (2025) · BMC Women s Health · doi:10.1186/s12905-025-03690-7 · Cited by 1 · see citing works
“Despite the growing recognition of these mechanisms, few interventions specifically target these cognitive dimensions, particularly in adolescent populations [31, 32].”
García-Pérez, L., González, M. D. M. C., & Mota, J. A. P. S. (2025) · Youth · doi:10.3390/youth5040116 · Cited by 1 · see citing works
“Common mechanisms, such as cognitive rumination (Wong et al., 2023), emotional hypervigilance (Meng et al., 2020), and difficulties in emotion regulation (Menefee et al., 2022), contribute to their interconnection.”
Huang, Q., Yue, F., Shi, W., Lei, Y., & Jiang, T. (2025) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1710386 · Cited by 1 · see citing works
Августюк, М. М., Балашов, Е. М., Pasichnyk, I., & Kalamazh, R. (2025) · East European Journal of Psycholinguistics · doi:10.29038/avh · Cited by 1 · see citing works
Neural correlates of rumination in psychiatric disorders: A systematic review of fMRI evidence
Carneiro, A. M., da Silva, V. A., Razza, L. B., Vanderhasselt, M., Brunoni, A. R., & da Silva, P. H. R. (2026) · Behavioural Brain Research · doi:10.1016/j.bbr.2026.116181 · Cited by 1 · see citing works
Gonzales, C. B. A., Rosales, M. G., Mista, C., Arévalo, D. A. (., Tabernig, C. B., & Manresa, J. A. B. (2026) · Cortex · doi:10.1016/j.cortex.2026.03.020 · Cited by 1 · see citing works
Aprile, S. F., Avanzato, C., Alù, F., Concerto, C., Cutrufelli, P., Mineo, L., Privitera, G., Petralia, A., Rodolico, A., Caraci, F., et al. (2026) · Brain Sciences · doi:10.3390/brainsci16060620 · Cited by 1 · see citing works
“This pattern aligns with contemporary transdiagnostic models that conceptualize repetitive negative thinking as a central mechanism cutting across internalizing symptom clusters and related complaints such as somatic distress [33].”
Homayoon, M., Damirchi, E. S., & Abdoli, A. (2026) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2026.101137 · Cited by 1 · see citing works
Tang, S., Yu, M., 张向晖, & Zhang, Z. (2026) · Computers in Human Behavior Reports · doi:10.1016/j.chbr.2026.101301 · Cited by 1 · see citing works
Individual Rumination in Adult Cancer Care: A Concept Analysis
Cao, J., & Üzar‐Özçetin, Y. S. (2025) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2024.151802 · Cited by 1 · see citing works
Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice.
Song, S., Irfan, M., Tahir, Z., Garrison, K. A., & Ziskind, S. (2026) · Current Sleep Medicine Reports · doi:10.1007/s40675-026-00370-2
Research Progress on the Psychopathological Mechanism of Bodily Distress Disorder
应, 修. (2024) · Advances in Psychology · doi:10.12677/ap.2024.148574
Rusconi, P., Ales, F., Giromini, L., & Ando, A. M. C. (2025) · Journal of Cognitive Psychology · doi:10.1080/20445911.2025.2449725
“…about one’s negative emotions and the events that caused them (e.g. Ferguson et al., 2024; Nolen-Hoeksema, 1991; Nolen-Hoeksema et al., 2008; Wong et al., 2023), often associated with avoidance (e.g. Ferguson et al., 2024; Wong et al., 2023) and usually viewed as a maladaptive emotion…”
Jiang, W., Shi, Z., & Zhang, X. (2025) · European Eating Disorders Review · doi:10.1002/erv.3207
Kumari, N., Mishra, N., & Shivani, S. (2026) · International Journal of Pharmaceutical and Healthcare Marketing · doi:10.1108/ijphm-06-2025-0121
Wang, Z., Ding, N., Ye, H., & Lin, L. (2026) · Applied Research in Quality of Life · doi:10.1007/s11482-026-10588-5
“For instance, the flow model of rumination posits that self-rumination highlights a psychological process that disrupts individual thinking (Wong et al., 2023).”
InfluentialCognitive–Discursive Organisation of Ruminative Narratives in Military Personnel
Августюк, М. М., Балашов, Е. М., Pasichnyk, I., & Borysenko, V. A. (2026) · PSYCHOLINGUISTICS · doi:10.31470/2309-1797-2026-39-1-6-34
Wu, P., Hu, D., Tian, S., Chen, S. H., & Pan, Y. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1817291
Coping with chaos: relationships between rumination, stress, and resilience in physicians
Erdoğan, N. O., & Erdoğan, İ. M. (2026) · Current Psychology · doi:10.1007/s12144-026-09582-9
“Over time, rumination has been increasingly recognized as a transdiagnostic cognitive feature, implicated in a broad spectrum of psychiatric disorders such as depression, anxiety, and psychosis (Kim et al., 2025; Luca, 2019; Moulds & McEvoy, 2025; Wong et al., 2023).”
Effectiveness of Paradox Therapy on Rumination and Ego Strength in Patients with Panic Disorder
Biabani, Y., Khademi, A., & Tabatabaei, S. M. (2026) · North Khorasan University of Medical Sciences · doi:10.66224/nkums.18.2.67
AI-Enhanced AR Wearable Technology for Memory and Cognitive Support in Dementia Care
Maheswari.S, Kalpana., S., Ranganathan, S., Venkatesan, S., & Subramanian, S. (2026) · International Conference on Trends in Quantum Computing and Emerging Business Technologies (TQCEBT) · doi:10.1109/tqcebt67648.2026.11681407
- Authors
- Wong, S. M. Y., Chen, E. Y. H., Lee, M. C. Y., Suen, Y. N., & Hui, C. L. M.
- Affiliations
- University of Hong Kong (HK)
- Corresponding author
- Chen, Eric Y. H.
- Venue
- Brain Sciences
- Publisher
- MDPI AG
- Published
- 2023-07-08
- Volume
- 13
- Issue
- 7
- Pages
- 1041
- ISSN
- 2076-3425 (ISSN-L)
- PMC
- PMC10377138
- OpenAlex
- W4383817969
- Cited by
- 48
- References
- 186
- Citations by year
- 2026: 14 · 2025: 25 · 2024: 8 · 2023: 1
- FWCI
- 2.03
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Brain Sciences (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- rumination, transdiagnostic mechanisms, depressive rumination, executive function, attention, psychosis, smartphone use, human-device interaction, mental health interventions
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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