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Prebiotics and the Health Benefits of Fiber: Current Regulatory Status, Future Research, and Goals,

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Brownawell, Amy M., Caers, Wim, Gibson, Glenn R., Kendall, Cyril W.C., Lewis, Kara D., Ringel, Yehuda, Slavin, Joanne L.·2012·The Journal of Nutrition
DOI 10.3945/jn.112.158147
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  1. Slavin, 2008, Position of the American Dietetic Association: health implications of dietary fiber., J Am Diet Assoc., 108, 1716, 10.1016/j.jada.2008.08.007 · DOI · Paper page
  2. Eshak, 2010, Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women., J Nutr., 140, 1445, 10.3945/jn.110.122358 · DOI · Paper page
  3. Mozaffarian, 2003, Cereal, fruit, and vegetable fiber intake and the risk of cardiovascular disease in elderly individuals., JAMA., 289, 1659, 10.1001/jama.289.13.1659 · DOI · Paper page
  4. Pietinen, 1996, Intake of dietary fiber and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study., Circulation., 94, 2720, 10.1161/01.CIR.94.11.2720 · DOI · Paper page
  5. Rimm, 1996, Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men., JAMA., 275, 447, 10.1001/jama.1996.03530300031036 · DOI · Paper page
  6. Wolk, 1999, Long-term intake of dietary fiber and decreased risk of coronary heart disease among women., JAMA., 281, 1998, 10.1001/jama.281.21.1998 · DOI · Paper page
  7. Fraser, 1992, A possible protective effect of nut consumption on risk of coronary heart disease. The Adventist Health Study., Arch Intern Med., 152, 1416, 10.1001/archinte.1992.00400190054010 · DOI · Paper page
  8. Jacobs, 1998, Whole-grain intake may reduce the risk of ischemic heart disease death in postmenopausal women: the Iowa Women's Health Study., Am J Clin Nutr., 68, 248, 10.1093/ajcn/68.2.248 · DOI · Paper page
  9. Morris, 1977, Diet and heart: a postscript., BMJ., 2, 1307, 10.1136/bmj.2.6098.1307 · DOI · Paper page
  10. Bolton-Smith, 1992, The Scottish Heart Health Study. Dietary intake by food frequency questionnaire and odds ratios for coronary heart disease risk. II. The antioxidant vitamins and fibre., Eur J Clin Nutr., 46, 85
  11. Todd, 1999, Dietary antioxidant vitamins and fiber in the etiology of cardiovascular disease and all-causes mortality: results from the Scottish Heart Health Study., Am J Epidemiol., 150, 1073, 10.1093/oxfordjournals.aje.a009931 · DOI
  12. Bazzano, 2003, Dietary fiber intake and reduced risk of coronary heart disease in US men and women: the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study., Arch Intern Med., 163, 1897, 10.1001/archinte.163.16.1897 · DOI · Paper page
  13. Jensen, 2004, Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men., Am J Clin Nutr., 80, 1492, 10.1093/ajcn/80.6.1492 · DOI · Paper page
  14. Khaw, 1987, Dietary fiber and reduced ischemic heart disease mortality rates in men and women: a 12-year prospective study., Am J Epidemiol., 126, 1093, 10.1093/oxfordjournals.aje.a114748 · DOI · Paper page
  15. Liu, 2002, A prospective study of dietary fiber intake and risk of cardiovascular disease among women., J Am Coll Cardiol., 39, 49, 10.1016/S0735-1097(01)01695-3 · DOI · Paper page
  16. Davis, 2006, Normal-weight adults consume more fiber and fruit than their age- and height-matched overweight/obese counterparts., J Am Diet Assoc., 106, 833, 10.1016/j.jada.2006.03.013 · DOI
  17. Howarth, 2005, Dietary fiber and fat are associated with excess weight in young and middle-aged US adults., J Am Diet Assoc., 105, 1365, 10.1016/j.jada.2005.06.001 · DOI
  18. Maskarinec, 2006, Trends and dietary determinants of overweight and obesity in a multiethnic population., Obesity (Silver Spring)., 14, 717, 10.1038/oby.2006.82 · DOI
  19. Tucker, 2009, Increasing total fiber intake reduces risk of weight and fat gains in women., J Nutr., 139, 576, 10.3945/jn.108.096685 · DOI · Paper page
  20. Ludwig, 1999, Dietary fiber, weight gain, and cardiovascular disease risk factors in young adults., JAMA., 282, 1539, 10.1001/jama.282.16.1539 · DOI · Paper page
  21. Schulze, 2007, Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis., Arch Intern Med., 167, 956, 10.1001/archinte.167.9.956 · DOI · Paper page
  22. Giacco, 2000, Long-term dietary treatment with increased amounts of fiber-rich low-glycemic index natural foods improves blood glucose control and reduces the number of hypoglycemic events in type 1 diabetic patients., Diabetes Care., 23, 1461, 10.2337/diacare.23.10.1461 · DOI · Paper page
  23. Kaline, 2007, The importance and effect of dietary fiber in diabetes prevention with particular consideration of whole grain products., Horm Metab Res., 39, 687, 10.1055/s-2007-985811 · DOI
  24. Simpson, 1981, A high carbohydrate leguminous fibre diet improves all aspects of diabetic control., Lancet., 1, 1, 10.1016/S0140-6736(81)90112-4 · DOI · Paper page
  25. Hopping, 2010, Dietary fiber, magnesium, and glycemic load alter risk of type 2 diabetes in a multiethnic cohort in Hawaii., J Nutr., 140, 68, 10.3945/jn.109.112441 · DOI
  26. Aldoori, 2002, Preventing diverticular disease. Review of recent evidence on high-fibre diets., Can Fam Physician., 48, 1632
  27. Gibson, 2010, Dietary prebiotics: current status and new definition., Food Science and Technology Bulletin: Functional Foods., 7, 1
  28. Cummings, 1991, The control and consequences of bacterial fermentation in the human colon., J Appl Bacteriol., 70, 443, 10.1111/j.1365-2672.1991.tb02739.x · DOI · Paper page
  29. Eckburg, 2005, Diversity of the human intestinal microbial flora., Science., 308, 1635, 10.1126/science.1110591 · DOI · Paper page
  30. Flint, 2007, Interactions and competition within the microbial community of the human colon: links between diet and health., Environ Microbiol., 9, 1101, 10.1111/j.1462-2920.2007.01281.x · DOI · Paper page
  31. Hague, 1997, Butyrate acts as a survival factor for colonic epithelial cells: further fuel for the in vivo versus in vitro debate., Gastroenterology., 112, 1036, 10.1053/gast.1997.v112.agast971036 · DOI
  32. Barcenilla, 2000, Phylogenetic relationships of butyrate-producing bacteria from the human gut., Appl Environ Microbiol., 66, 1654, 10.1128/AEM.66.4.1654-1661.2000 · DOI · Paper page
  33. Juhlin-Dannfelt, 1977, Ethanol effects of substrate utilization by the human brain., Scand J Clin Lab Invest., 37, 443, 10.3109/00365517709091505 · DOI
  34. Lindeneg, 1964, Myocardial utilization of acetate, lactate and free fatty acids after ingestion of ethanol., Clin Sci., 27, 427
  35. Lundquist, 1973, Utilization of acetate in the human forearm during exercise after ethanol ingestion., J Clin Invest., 52, 3231, 10.1172/JCI107523 · DOI
  36. Landau, 1993, 14C-labeled propionate metabolism in vivo and estimates of hepatic gluconeogenesis relative to Krebs cycle flux., Am J Physiol., 265, E636
  37. Topping, 2001, Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides., Physiol Rev., 81, 1031, 10.1152/physrev.2001.81.3.1031 · DOI · Paper page
  38. Smith, 1996, Enumeration of human colonic bacteria producing phenolic and indolic compounds: effects of pH, carbohydrate availability and retention time on dissimilatory aromatic amino acid metabolism., J Appl Bacteriol., 81, 288, 10.1111/j.1365-2672.1996.tb04331.x · DOI · Paper page
  39. Thornton, 1981, High colonic pH promotes colorectal cancer., Lancet., 1, 1081, 10.1016/S0140-6736(81)92244-3 · DOI · Paper page
  40. Field, 1999, The fermentable fiber content of the diet alters the function and composition of canine gut associated lymphoid tissue., Vet Immunol Immunopathol., 72, 325, 10.1016/S0165-2427(99)00148-8 · DOI
  41. Pierre, 1997, Short-chain fructo-oligosaccharides reduce the occurrence of colon tumors and develop gut-associated lymphoid tissue in Min mice., Cancer Res., 57, 225
  42. Gaskins, 1996, Dietary fructo-oligosaccharide modulates large intestinal inflammatory responses to Clostridium difficile in antibiotic-compromised mice., Microb Ecol Health Dis., 9, 157, 10.1002/(SICI)1234-987X(199607)9:4<157::AID-MEH424>3.3.CO;2-M · doi:10.1002/(sici)1234-987x(199607)9:4<157::aid-meh424>3.3.co;2-m
  43. Abreu, 2003, Immunologic regulation of toll-like receptors in gut epithelium., Curr Opin Gastroenterol., 19, 559, 10.1097/00001574-200311000-00008 · DOI
  44. Gibson, 1995, Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics., J Nutr., 125, 1401, 10.1093/jn/125.6.1401 · DOI · Paper page
  45. Gibson, 2004, Dietary modulation of the human colonic microbiota: updating the concept of prebiotics., Nutr Res Rev., 17, 259, 10.1079/NRR200479 · DOI · Paper page
  46. van Loo, 1995, On the presence of inulin and oligofructose as natural ingredients in the western diet., Crit Rev Food Sci Nutr., 35, 525, 10.1080/10408399509527714 · DOI · Paper page
  47. Moshfegh, 1999, Presence of inulin and oligofructose in the diets of Americans., J Nutr., 129, S1407, 10.1093/jn/129.7.1407S · DOI · Paper page
  48. Coussement, 1999, Inulin and oligofructose: safe intakes and legal status., J Nutr., 129, S1412, 10.1093/jn/129.7.1412S · DOI · Paper page
  49. Speigel, 1994, Safety and benefits of fructooligosaccharides as food ingredients., Food Technol., 48, 85
  50. Briet, 1995, Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly., Eur J Clin Nutr., 49, 501
  51. Livesey, 2001, Tolerance of low-digestible carbohydrates: a general view., Br J Nutr., 85, S7, 10.1079/BJN2000257 · DOI
  52. Rogosa, 1974, Genus III. Bifidobacterium Orla-Fensen 1924, 472, 669
  53. Livesey, 1992, The energy values of dietary fibre and sugar alcohols for man., Nutr Res Rev., 5, 61, 10.1079/NRR19920007 · DOI
  54. Roberfroid, 1993, The biochemistry of oligofructose, a nondigestible fiber: an approach to calculate its caloric value., Nutr Rev., 51, 137, 10.1111/j.1753-4887.1993.tb03090.x · DOI · Paper page
  55. Roberfroid, 1999, Caloric value of inulin and oligofructose., J Nutr., 129, S1436, 10.1093/jn/129.7.1436S · DOI · Paper page
  56. 1999, Scientific concepts of functional foods in Europe. Consensus document., Br J Nutr., 81, S1
  57. Cummings, 2001, A study of fructo oligosaccharides in the prevention of travellers' diarrhoea., Aliment Pharmacol Ther., 15, 1139, 10.1046/j.1365-2036.2001.01043.x · DOI · Paper page
  58. Lewis, 2005, Effect of the prebiotic oligofructose on relapse of Clostridium difficile-associated diarrhea: a randomized, controlled study., Clin Gastroenterol Hepatol., 3, 442, 10.1016/S1542-3565(04)00677-9 · DOI · Paper page
  59. Welters, 2002, Effect of dietary inulin supplementation on inflammation of pouch mucosa in patients with an ileal pouch-anal anastomosis., Dis Colon Rectum., 45, 621, 10.1007/s10350-004-6257-2 · DOI · Paper page
  60. Furrie, 2005, Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial., Gut., 54, 242, 10.1136/gut.2004.044834 · DOI · Paper page
  61. Casellas, 2007, Oral oligofructose-enriched inulin supplementation in acute ulcerative colitis is well tolerated and associated with lowered faecal calprotectin., Aliment Pharmacol Ther., 25, 1061, 10.1111/j.1365-2036.2007.03288.x · DOI · Paper page
  62. Boutron-Ruault, 2005, Effects of a 3-mo consumption of short-chain fructo-oligosaccharides on parameters of colorectal carcinogenesis in patients with or without small or large colorectal adenomas., Nutr Cancer., 53, 160, 10.1207/s15327914nc5302_5 · DOI
  63. Rafter, 2007, Dietary synbiotics reduce cancer risk factors in polypectomized and colon cancer patients., Am J Clin Nutr., 85, 488, 10.1093/ajcn/85.2.488 · DOI · Paper page
  64. Limburg, 2011, Randomized phase II trial of sulindac, atorvastatin, and prebiotic dietary fiber for colorectal cancer chemoprevention., Cancer Prev Res (Phila)., 4, 259, 10.1158/1940-6207.CAPR-10-0215 · DOI
  65. Fuchs, 1999, Dietary fiber and the risk of colorectal cancer and adenoma in women., N Engl J Med., 340, 169, 10.1056/NEJM199901213400301 · DOI · Paper page
  66. Coudray, 1998, Do oligosaccharides affect the intestinal absorption of calcium in humans?, Am J Clin Nutr., 68, 921, 10.1093/ajcn/68.4.921 · doi:10.1093/ajcn/68.4.921
  67. van den Heuvel, 2000, Transgalactooligosaccharides stimulate calcium absorption in postmenopausal women., J Nutr., 130, 2938, 10.1093/jn/130.12.2938 · DOI · Paper page
  68. Tahiri, 2003, Effect of short-chain fructooligosaccharides on intestinal calcium absorption and calcium status in postmenopausal women: a stable-isotope study., Am J Clin Nutr., 77, 449, 10.1093/ajcn/77.2.449 · DOI
  69. Demigné, 2008, Comparison of native or reformulated chicory fructans, or non-purified chicory, on rat cecal fermentation and mineral metabolism., Eur J Nutr., 47, 366, 10.1007/s00394-008-0736-5 · DOI
  70. Abrams, 2005, A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents., Am J Clin Nutr., 82, 471, 10.1093/ajcn/82.2.471 · DOI · Paper page
  71. Abrams, 2007, Effect of prebiotic supplementation and calcium intake on body mass index., J Pediatr., 151, 293, 10.1016/j.jpeds.2007.03.043 · DOI
  72. Jenkins, 2001, Effect of a very-high-fiber vegetable, fruit, and nut diet on serum lipids and colonic function., Metabolism., 50, 494, 10.1053/meta.2001.21037 · DOI · Paper page
  73. Jenkins, 2003, Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein., JAMA., 290, 502, 10.1001/jama.290.4.502 · DOI · Paper page
  74. Davidson, 1999, Effects of dietary inulin on serum lipids., J Nutr., 129, S1474, 10.1093/jn/129.7.1474S · DOI
  75. Forcheron, 2007, Long-term administration of inulin-type fructans has no significant lipid-lowering effect in normolipidemic humans., Metabolism., 56, 1093, 10.1016/j.metabol.2007.03.019 · DOI
  76. Wong, 2010, The effect on the blood lipid profile of soy foods combined with a prebiotic: a randomized controlled trial., Metabolism., 59, 1331, 10.1016/j.metabol.2009.12.017 · DOI
  77. Nadal, 2009, Shifts in clostridia, bacteroides and immunoglobulin-coating fecal bacteria associated with weight loss in obese adolescents., Int J Obes (Lond)., 33, 758, 10.1038/ijo.2008.260 · DOI · Paper page
  78. Turnbaugh, 2009, A core gut microbiome in obese and lean twins., Nature., 457, 480, 10.1038/nature07540 · DOI · Paper page
  79. Duncan, 2008, Human colonic microbiota associated with diet, obesity and weight loss., Int J Obes (Lond)., 32, 1720, 10.1038/ijo.2008.155 · DOI · Paper page
  80. Santacruz, 2009, Interplay between weight loss and gut microbiota composition in overweight adolescents., Obesity (Silver Spring)., 17, 1906, 10.1038/oby.2009.112 · DOI · Paper page
  81. Santacruz, 2010, Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women., Br J Nutr., 104, 83, 10.1017/S0007114510000176 · DOI · Paper page
  82. Peters, 2009, No effect of added β-glucan or of fructooligosaccharide on appetite or energy intake., Am J Clin Nutr., 89, 58, 10.3945/ajcn.2008.26701 · DOI
  83. Archer, 2004, Effect of fat replacement by inulin or lupin-kernel fibre on sausage patty acceptability, post-meal perceptions of satiety and food intake in men., Br J Nutr., 91, 591, 10.1079/BJN20031088 · DOI · Paper page
  84. Parnell, 2009, Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults., Am J Clin Nutr., 89, 1751, 10.3945/ajcn.2009.27465 · DOI · Paper page
  85. Cani, 2009, Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal., Am J Clin Nutr., 90, 1236, 10.3945/ajcn.2009.28095 · DOI · Paper page
  86. Cani, 2006, Oligofructose promotes satiety in healthy human: a pilot study., Eur J Clin Nutr., 60, 567, 10.1038/sj.ejcn.1602350 · DOI · Paper page
  87. Hess, 2011, Effects of short-chain fructooligosaccharides on satiety responses in healthy men and women., Appetite., 56, 128, 10.1016/j.appet.2010.12.005 · DOI
  88. Food and Drug Administration Thailand. Prebiotics [in Thai]. Medical and health product bulletin; 2011 [cited 2011 Mar 8]. 5:1–31. Available from: http://www.fda.moph.go.th/fda-net/html/product/apr/about/bulletin%205–4.pdf.
  89. Southeast Asia Region ILSI. Seminar and Workshop on Nutrition Labeling, Claims and Communication Strategies for the Consumer, Sept 20–21; 2010, Kuala Lumpur, Malaysia, Meeting Summary. ILSI Southeast Asia Region 2010 [cited 2011 Mar 9]. Available from: http://www.ilsi.org/SEA_Region/Documents/Nutrition%20Labeling%20Claim%20Meeting%20Summary%20Sept2010.pdf.
  90. 2010, 9th Vahouny Fibre Symposium: Session 10: implementation Issues of the Codex definition of dietary fibre. Part 2.
  91. Howlett, 2010, The definition of dietary fiber: discussions at the Ninth Vahouny Fiber Symposium: building scientific agreement., Food Nutr Res., 54, 5750, 10.3402/fnr.v54i0.5750 · DOI
  92. Pineiro, 2008, FAO Technical meeting on prebiotics., J Clin Gastroenterol., 42, S156, 10.1097/MCG.0b013e31817f184e · DOI · Paper page
  93. Geier, 2007, Prebiotic and synbiotic fructooligosaccharide administration fails to reduce the severity of experimental colitis in rats., Dis Colon Rectum., 50, 1061, 10.1007/s10350-007-0213-x · doi:10.1007/s10350-007-0213-x
  94. Life Sciences Research Organization. Workshop on Prebiotics and the Health Benefits of Fiber: future research and goals. Life Sciences Research Organization; 2011 [cited 2011 Feb 18]. Available from: http://www.lsro.org/prebiotics/prebiotics_summary4wkshp.html.

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Metadata

Authors
Brownawell, A. M., Caers, W., Gibson, G. R., Kendall, C. W. C., Lewis, K. D., Ringel, Y., & Slavin, J. L.
Venue
The Journal of Nutrition
Publisher
Elsevier BV
Published
2012-05
Volume
142
Issue
5
Pages
962-974
ISSN
0022-3166 (ISSN-L)
DOI
10.3945/jn.112.158147
OpenAlex
W2170886805
Cited by
248
References
18
FWCI
18.16
Type
journal article
Language
en
Open access
bronze
Licence

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Brownawell, A. M., Caers, W., Gibson, G. R., Kendall, C. W. C., Lewis, K. D., Ringel, Y., & Slavin, J. L. (2012). Prebiotics and the Health Benefits of Fiber: Current Regulatory Status, Future Research, and Goals,. The Journal of Nutrition. https://doi.org/10.3945/jn.112.158147

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