Keaney, John F.

The clinical implications of endothelial dysfunction

Widlansky, M. E., Gokce, N., Keaney, J. F., & Vita, J. A. (2003) · Journal of the American College of Cardiology

Cardiovascular Health and Disease PreventionNitric Oxide and Endothelin Effects

Cited by 1,749

Obesity and Systemic Oxidative Stress: Clinical Correlates of Oxidative Stress in The Framingham Study

Keaney, J. F., Larson, M. G., Vasan, R. S., Wilson, P. W. F., Lipinska, I., Corey, D., Massaro, J. M., Sutherland, P., Vita, J. A., & Benjamin, E. J. (2003) · Arteriosclerosis, Thrombosis, and Vascular Biology

Antioxidant Activity and Oxidative StressNitric Oxide and Endothelin Effects

Cited by 1,304

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

Stamler, J. S., Jaraki, O., Osborne, J., Simon, D. I., Keaney, J., Vita, J., Singel, D., Valeri, C. R., & Loscalzo, J. (1992) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 1,238

Reactive oxygen species in cardiovascular disease

Sugamura, K., & Keaney (2011) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsAntioxidant Activity and Oxidative Stress

Cited by 769

Ascorbic Acid Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease

Levine, G. N., Frei, B., Koulouris, S. N., Gerhard, M. D., Keaney, J. F., & Vita, J. A. (1996) · Circulation

Cardiovascular Health and Disease PreventionNitric Oxide and Endothelin Effects

Cited by 582

Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study

Demissie, S., Levy, D., Benjamin, E. J., Cupples, L. A., Gardner, J. P., Herbert, A., Kimura, M., Larson, M. G., Meigs, J. B., Keaney, J. F., et al. (2006) · Aging Cell

Telomeres, Telomerase, and SenescenceCardiovascular Health and Disease Prevention

Cited by 508

Physical Inactivity Rapidly Induces Insulin Resistance and Microvascular Dysfunction in Healthy Volunteers

Hamburg, N. M., McMackin, C. J., Huang, A. L., Shenouda, S. M., Widlansky, M. E., Schulz, E., Gokce, N., Ruderman, N. B., Keaney, J. F., & Vita, J. A. (2007) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cardiovascular and exercise physiologyCardiovascular Health and Disease Prevention

Cited by 474

Association of Nitrotyrosine Levels With Cardiovascular Disease and Modulation by Statin Therapy

Shishehbor, M. H., Aviles, R. J., Brennan, M.-L., Fu, X., Goormastic, M., Pearce, G. L., Gokce, N., Keaney, J. F., Penn, M. S., Sprecher, D. L., et al. (2003) · JAMA

Nitric Oxide and Endothelin EffectsLipoproteins and Cardiovascular Health

Cited by 464

Ascorbate prevents the interaction of superoxide and nitric oxide only at very high physiological concentrations

Jackson, T. S., Xu, A., Vita, J. A., & Keaney, J. F. (1998) · Circulation Research

Nitric Oxide and Endothelin EffectsAntioxidant Activity and Oxidative Stress

Cited by 400

Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications

Münzel, T., Gori, T., Keaney, J. F., Maack, C., & Daiber, A. (2015) · European Heart Journal

Nitric Oxide and Endothelin EffectsCardiovascular Function and Risk Factors

Cited by 394

Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease

Gokce, N., Keaney, J. F., Frei, B., Holbrook, M., Olesiak, M., Zachariah, B. J., Leeuwenburgh, C., Heinecke, J. W., & Vita, J. A. (1999) · Circulation

Cardiovascular Health and Disease PreventionNitric Oxide and Endothelin Effects

Cited by 387

Hydrogen Peroxide Activates Endothelial Nitric-oxide Synthase through Coordinated Phosphorylation and Dephosphorylation via a Phosphoinositide 3-Kinase-dependent Signaling Pathway

Thomas, S. R., Chen, K., & Keaney, J. F. (2002) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 381

Vitamin K and vitamin D status: associations with inflammatory markers in the Framingham Offspring Study

Shea, M. K., Booth, S. L., Massaro, J. M., Jacques, P. F., D'Agostino, R. B., Dawson-Hughes, B., Ordovas, J. M., O'Donnell, C. J., Kathiresan, S., Keaney, J. F., et al. (2007) · American Journal of Epidemiology

Vitamin K Research StudiesVitamin D Research Studies

Cited by 316

Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance

Sydow, K., Daiber, A., Oelze, M., Chen, Z., August, M., Wendt, M., Ullrich, V., Mülsch, A., Schulz, E., Keaney, J. F., et al. (2004) · Journal of Clinical Investigation

Nitric Oxide and Endothelin EffectsMitochondrial Function and Pathology

Cited by 300

NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation

Craige, S. M., Chen, K., Pei, Y., Li, C., Huang, X., Chen;, C., Shibata, R., Sato, K., Walsh, K., & Keaney, J. F. (2011) · Circulation

Nitric Oxide and Endothelin EffectsAngiogenesis and VEGF in Cancer

Cited by 283

Iron Chelation Improves Endothelial Function in Patients With Coronary Artery Disease

Duffy, S. J., Biegelsen, E. S., Holbrook, M., Russell, J. D., Gokce, N., Keaney, J. F., & Vita, J. A. (2001) · Circulation

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 271

Association of Oxidative Stress, Insulin Resistance, and Diabetes Risk Phenotypes

Meigs, J. B., Larson, M. G., Fox, C. S., Keaney, J. F., Vasan, R. S., & Benjamin, E. J. (2007) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsAntioxidant Activity and Oxidative Stress

Cited by 220

New insights on oxidative stress in the artery wall

STOCKER, R., & KEANEY, J. F. (2005) · Journal of Thrombosis and Haemostasis

Atherosclerosis and Cardiovascular DiseasesNitric Oxide and Endothelin Effects

Cited by 188

Effects of black tea consumption on plasma catechins and markers of oxidative stress and inflammation in patients with coronary artery disease

Widlansky, M. E., Duffy, S. J., Hamburg, N. M., Gokce, N., Warden, B. A., Wiseman, S., Keaney, J. F., Frei, B., & Vita, J. A. (2005) · Free Radical Biology and Medicine

Tea Polyphenols and EffectsPhytochemicals and Antioxidant Activities

Cited by 162

Activation of Endothelial Nitric-oxide Synthase by the p38 MAPK in Response to Black Tea Polyphenols

Anter, E., Thomas, S. R., Schulz, E., Shapira, O. M., Vita, J. A., & Keaney, J. F. (2004) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsTea Polyphenols and Effects

Cited by 142

Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4

Wendt, M. C., Daiber, A., Kleschyov, A. L., Mülsch, A., Sydow, K., Schulz, E., Chen, K., Keaney, J. F., Lassègue, B., Walter, U., et al. (2005) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 122

Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study)

McManus, D. D., Tanriverdi, K., Lin, H., Esa, N., Kinno, M., Mandapati, D., Tam, S., Okike, O. N., Ellinor, P. T., Keaney, J. F., et al. (2015) · Heart Rhythm

Atrial Fibrillation Management and OutcomesMicroRNA in disease regulation

Cited by 116

Activation of p53 by Oxidative Stress Involves Platelet-derived Growth Factor-β Receptor-mediated Ataxia Telangiectasia Mutated (ATM) Kinase Activation

Chen, K., Albano, A., Ho, A., & Keaney, J. F. (2003) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysRedox biology and oxidative stress

Cited by 95

Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesions

Craige, S. M., Kant, S., Reif, M., Chen, K., Pei, Y., Angoff, R., Sugamura, K., Fitzgibbons, T., & Keaney, J. F. (2015) · Free Radical Biology and Medicine

Atherosclerosis and Cardiovascular DiseasesNitric Oxide and Endothelin Effects

Cited by 85