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Cited by 32Substance Abuse Treatment and OutcomesOpioid Use Disorder TreatmentHIV, Drug Use, Sexual Risk

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Psychosocial interventions for stimulant use disorder

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Minozzi, Silvia, Saulle, Rosella, Amato, Laura, Traccis, Francesco, Agabio, Roberta·2024·Cochrane Database of Systematic Reviews
DOI 10.1002/14651858.cd011866.pub3PMC PMC10867898
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Abstract

BACKGROUND: Stimulant use disorder is a continuously growing medical and social burden without approved medications available for its treatment. Psychosocial interventions could be a valid approach to help people reduce or cease stimulant consumption. This is an update of a Cochrane review first published in 2016. OBJECTIVES: To assess the efficacy and safety of psychosocial interventions for stimulant use disorder in adults. SEARCH METHODS: We searched the Cochrane Drugs and Alcohol Group Specialised Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, three other databases, and two trials registers in September 2023. All searches included non-English language literature. We handsearched the references of topic-related systematic reviews and the included studies. SELECTION CRITERIA: We included randomised controlled trials (RCTs) comparing any psychosocial intervention with no intervention, treatment as usual (TAU), or a different intervention in adults with stimulant use disorder. DATA COLLECTION AND ANALYSIS: We used the standard methodological procedures expected by Cochrane. MAIN RESULTS: We included a total of 64 RCTs (8241 participants). Seventy-three percent of studies included participants with cocaine or crack cocaine use disorder; 3.1% included participants with amphetamine use disorder; 10.9% included participants with methamphetamine use disorder; and 12.5% included participants with any stimulant use disorder. In 18 studies, all participants were in methadone maintenance treatment. In our primary comparison of any psychosocial treatment to no intervention, we included studies which compared a psychosocial intervention plus TAU to TAU alone. In this comparison, 12 studies evaluated cognitive behavioural therapy (CBT), 27 contingency management, three motivational interviewing, one study looked at psychodynamic therapy, and one study evaluated CBT plus contingency management. We also compared any psychosocial intervention to TAU. In this comparison, seven studies evaluated CBT, two contingency management, two motivational interviewing, and one evaluated a combination of CBT plus motivational interviewing. Seven studies compared contingency management reinforcement related to abstinence versus contingency management not related to abstinence. Finally, seven studies compared two different psychosocial approaches. We judged 65.6% of the studies to be at low risk of bias for random sequence generation and 19% at low risk for allocation concealment. Blinding of personnel and participants was not possible for the type of intervention, so we judged all the studies to be at high risk of performance bias for subjective outcomes but at low risk for objective outcomes. We judged 22% of the studies to be at low risk of detection bias for subjective outcomes. We judged most of the studies (69%) to be at low risk of attrition bias. When compared to no intervention, we found that psychosocial treatments: reduce the dropout rate (risk ratio (RR) 0.82, 95% confidence interval (CI) 0.74 to 0.91; 30 studies, 4078 participants; high-certainty evidence); make little to no difference to point abstinence at the end of treatment (RR 1.15, 95% CI 0.94 to 1.41; 12 studies, 1293 participants; high-certainty evidence); make little to no difference to point abstinence at the longest follow-up (RR 1.22, 95% CI 0.91 to 1.62; 9 studies, 1187 participants; high-certainty evidence); probably increase continuous abstinence at the end of treatment (RR 1.89, 95% CI 1.20 to 2.97; 12 studies, 1770 participants; moderate-certainty evidence); may make little to no difference in continuous abstinence at the longest follow-up (RR 1.14, 95% CI 0.89 to 1.46; 4 studies, 295 participants; low-certainty evidence); reduce the frequency of drug intake at the end of treatment (standardised mean difference (SMD) -0.35, 95% CI -0.50 to -0.19; 10 studies, 1215 participants; high-certainty evidence); and increase the longest period of abstinence (SMD 0.54, 95% CI 0.41 to 0.68; 17 studies, 2118 participants; high-certainty evidence). When compared to TAU, we found that psychosocial treatments reduce the dropout rate (RR 0.79, 95% CI 0.65 to 0.97; 9 studies, 735 participants; high-certainty evidence) and may make little to no difference in point abstinence at the end of treatment (RR 1.67, 95% CI 0.64 to 4.31; 1 study, 128 participants; low-certainty evidence). We are uncertain whether they make any difference in point abstinence at the longest follow-up (RR 1.31, 95% CI 0.86 to 1.99; 2 studies, 124 participants; very low-certainty evidence). Compared to TAU, psychosocial treatments may make little to no difference in continuous abstinence at the end of treatment (RR 1.18, 95% CI 0.92 to 1.53; 1 study, 128 participants; low-certainty evidence); probably make little to no difference in the frequency of drug intake at the end of treatment (SMD -1.17, 95% CI -2.81 to 0.47, 4 studies, 479 participants, moderate-certainty ev

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  1. Crits-Christoph, 1999, Psychosocial treatments for cocaine dependence: National Institute of Drug Abuse Collaborative Cocaine Treatment Study, Archives of General Psychiatry, 56, 493, 10.1001/archpsyc.56.6.493 · DOI
  2. Higgins, 1995, Outpatient behavioral treatment for cocaine dependence. one-year outcome, Experimental and Clinical Psychopharmacology, 3, 205, 10.1037/1064-1297.3.2.205 · DOI
  3. Farabee, 2002, Adoption of drug avoidance activities among patients in contingency management and cognitive-behavioral treatments, Journal of Substance Abuse Treatment, 23, 343, 10.1016/S0740-5472(02)00297-0 · DOI · Paper page
  4. Farabee, 2002, Adoption of drug avoidance activities among patients in contingency management and cognitive-behavioral treatments, Journal of Substance Abuse Treatment, 23, 343, 10.1016/S0740-5472(02)00297-0 · DOI · Paper page
  5. Farabee, 2002, Adoption of drug avoidance activities among patients in contingency management and cognitive-behavioral treatments, Journal of Substance Abuse Treatment, 23, 343, 10.1016/S0740-5472(02)00297-0 · DOI · Paper page
  6. Sanchez-Hervas, 2008, Psychological treatment for cocaine addicts in public health services, Trastornos adictivos, 10, 275
  7. Sanchez-Hervas, 2008, Community reinforcement approach (CRA) for cocaine addicts: establishment in a public health setting, Anales de Psiquiatria, 24, 153
  8. Shoptaw, 2005, Behavioral treatment approaches for methamphetamine dependence and HIV-related sexual risk behaviors among urban gay and bisexual men, Drug and Alcohol Dependence, 78, 125, 10.1016/j.drugalcdep.2004.10.004 · DOI · Paper page
  9. Shoptaw, 2005, Behavioral treatment approaches for methamphetamine dependence and HIV-related sexual risk behaviors among urban gay and bisexual men., Drug and Alcohol Dependence, 78, 125, 10.1016/j.drugalcdep.2004.10.004 · DOI · Paper page
  10. Kalapatapu R Cognitive rehabilitation for cocaine use disorder Dissertation submitted in partial satisfaction of the requirements for degree of Doctor of Philosophy 2021
  11. Beck, 1996, Manual for the Beck Depression Inventory-II
  12. Committee on developing evidence-based standards for psychosocial interventions for Mental Disorders, 2015, Psychosocial interventions for mental and substance use disorders: a framework for establishing evidence-based standards
  13. Deeks JJ Higgins JP Altman DG on behalf of the Cochrane Statistical Methods Group Chapter 10: Analysing data and undertaking meta-analyses. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022 Available from www.training.cochrane.org/handbook
  14. Higgins JPT Eldridge S Chapter 23: Including variants on randomized trials. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane, 2023 Available from www.training.cochrane.org/handbook
  15. Lefebvre C Manheimer E Glanville J Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org
  16. Miller, 1992, Motivational enhancement therapy manual: a clinical research guide for therapists treating individuals with alcohol abuse and dependence
  17. United Nations Office on Drugs and Crime, 2022, World Drug Report

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Metadata

Authors
Minozzi, S., Saulle, R., Amato, L., Traccis, F., & Agabio, R.
Affiliations
  • Regione Lazio (IT)
  • University of Cagliari (IT)
ORCID
Venue
Cochrane Database of Systematic Reviews
Publisher
Wiley
Published
2024-02-15
Volume
2024
Issue
2
Pages
CD011866-CD011866
ISSN
  • 1361-6137 (ISSN-L)
  • 1465-1858
DOI
10.1002/14651858.cd011866.pub3
PMC
PMC10867898
OpenAlex
W4391840511
Cited by
32
References
280
Citations by year
2026: 6 · 2025: 19 · 2024: 6
FWCI
2.04
Type
journal article
Language
en
Open access
Locations
  • Cochrane Database of Systematic Reviews (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion)
Funders
  • National Institutes of Health (AA03510)
  • National Institute on Drug Abuse (DA09241., P50DA009241, P50-DA-0-9241, R01DA013444)
  • National Center for Research Resources (M01RR006192)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
  • Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
Keywords
stimulant use disorder, psychosocial interventions, cocaine dependence, crack cocaine, amphetamine use disorder, methamphetamine, cognitive behavioral therapy, contingency management, motivational interviewing, psychodynamic psychotherapy, methadone maintenance treatment, treatment efficacy, treatment safety, relapse, treatment discontinuation, medication adherence, treatment acceptability
MeSH terms
Psychosocial Intervention, Adult, Counseling, Humans, Cognitive Behavioral Therapy, Substance-Related Disorders, Motivational Interviewing

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