Cited by 121Neuroscience and Music PerceptionInfant Health and DevelopmentTactile and Sensory Interactions

FMRI activations of amygdala, cingulate cortex, and auditory cortex by infant laughing and crying

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Sander, Kerstin, Frome, Yvonne, Scheich, Henning·2007·Human Brain Mapping

Abstract

One of the functions of emotional vocalizations is the regulation of social relationships like those between adults and children. Listening to infant vocalizations is known to engage amygdala as well as anterior and posterior cingulate cortices. But, the functional relationships between these structures still need further clarification. Here, nonparental women and men listened to laughing and crying of preverbal infants and to vocalization-derived control stimuli, while performing a pure tone detection task during low-noise functional magnetic resonance imaging. Infant vocalizations elicited stronger activation in amygdala and anterior cingulate cortex (ACC) of women, whereas the alienated control stimuli elicited stronger activation in men. Independent of listeners' gender, auditory cortex (AC) and posterior cingulate cortex (PCC) were more strongly activated by the control stimuli than by infant laughing or crying. The gender-dependent correlates of neural activity in amygdala and ACC may reflect neural predispositions in women for responses to preverbal infant vocalizations, whereas the gender-independent similarity of activation patterns in PCC and AC may reflect more sensory-based and cognitive levels of neural processing. In comparison to our previous work on adult laughing and crying, the infant vocalizations elicited manifold higher amygdala activation.

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  • Infant laughing and crying stimuli versus a control sound activated the amygdala and anterior cingulate of women, while the control stimuli elicited stronger activations in men.

    “Sander and colleagues also report a striking gender effect with infant laughing and crying stimuli vs. a control sound activating the amygdala and anterior cingulate of women, while the control stimuli elicited stronger activations in men.”

    From The human parental brain: In vivo neuroimaging (2011) · cites this paper as Sander et al., 2007

  • Independent of listeners' gender, auditory cortex and posterior cingulate were more strongly activated by the control stimuli than by infant laughing or crying.

    “Independent of listeners’ gender, auditory cortex and posterior cingulate were more strongly activated by the control stimuli than by infant laughing or crying”

    From The human parental brain: In vivo neuroimaging (2011) · cites this paper as Sander et al., 2007

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Research works printed but not linked: 2

  1. Frodi A (1985): Variations in parental and nonparental response to early infant communication. In: Reite M, Field T, editors. The Psychobiology of Attachment and Separation. Orlando: Aca- demic Press. pp 351-367
  2. Gaschler B, Schindler F, Scheich H (1996): KHORFu: A KHOROS- based functional image post processing system. A statistical software package for functional magnetic resonance imaging and other neuroimage data sets. In: Prat A, editor. COMPSTAT 1996: Proceedings in Computational Statistics. Twelth Sympo- sium held in Barcelona, Spain, 1996. Heidelberg: Physica-Verlag. pp 57-58.

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Authors
Sander, K., Frome, Y., & Scheich, H.
Affiliations
Leibniz Institute for Neurobiology (DE)
Venue
Human Brain Mapping
Publisher
Wiley
Published
2007-03-14
Volume
28
Issue
10
Pages
1007-1022
ISSN
  • 1065-9471 (ISSN-L)
  • 1097-0193
OpenAlex
W2085444152
Cited by
121
References
77
Citations by year
2026: 2 · 2025: 3 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 5 · 2020: 6 · 2019: 5 · 2018: 5 · 2017: 5 · 2016: 9 · 2015: 7 · 2014: 16 · 2013: 7 · 2012: 11
FWCI
4.16
Type
journal article
Language
en
Open access
Locations
  • Human Brain Mapping (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
Deutsche Forschungsgemeinschaft (SFB 426)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
  • Health Sciences › Health Professions › Pharmacy › Infant Health and Development
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
Keywords
infant vocalizations, infant laughter, infant crying, preverbal infants, amygdala, anterior cingulate cortex, posterior cingulate cortex, auditory cortex, gender differences, emotional vocalizations, neural correlates of emotion
MeSH terms
Acoustic Stimulation, Adult, Amygdala, Auditory Cortex, Auditory Perception, Brain, Brain Mapping, Cognition, Crying, Emotions, Female, Gyrus Cinguli, Humans, Infant, Functional Laterality, Laughter, Magnetic Resonance Imaging, Male, Maternal Behavior, Neuropsychological Tests, Paternal Behavior, Sex Characteristics, Social Behavior

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