Action of thyroid hormone in brain

Principles of neural science

(1982) · Trends in Neurosciences · doi:10.1016/0166-2236(82)90076-5 · Cited by 9,089

Williams Textbook of Endocrinology

(2016) · Elsevier eBooks · doi:10.1016/c2013-0-15980-6 · Cited by 3,711

Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child

Haddow, J. E., Palomaki, G. E., Allan, W. C., Williams, J. R., Knight, G. J., Gagnon, J., O'Heir, C. E., Mitchell, M. L., Hermos, R. J., Waisbren, S. E., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908193410801 · Cited by 2,558

The Thyroid Gland.

Ingbar, S. H. (1965) · Archives of Internal Medicine · doi:10.1001/archinte.1965.03870060154035 · Cited by 1,743

The Regulation of Thyroid Function in Pregnancy: Pathways of Endocrine Adaptation from Physiology to Pathology

Glinoer, D. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.3.0300 · Cited by 1,364

Williams Textbook of Endocrinology

Stoffer, S. S. (1999) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.281.9.851 · Cited by 1,253

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

Milbrandt, J. (1987) · Science · doi:10.1126/science.3672127 · Cited by 1,172

Fundamental Neuroscience

Arbuthnott, G. W. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01495-2 · Cited by 1,113

Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy

Pop, V. J., Kuijpens, J. L., van Baar, A. L., Verkerk, G., van Son, M. M., de Vijlder, J. J., Vulsma, T., Wiersinga, W. M., Drexhage, H. A., & Vader, H. L. (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00639.x · Cited by 1,009

Metabolic coupling between glia and neurons

Tsacopoulos, M., & Magistretti, P. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-03-00877.1996 · Cited by 1,006

Type I iodothyronine deiodinase is a selenocysteine-containing enzyme

Berry, M. J., Banu, L., & Larsen, P. R. (1991) · Nature · doi:10.1038/349438a0 · Cited by 883

Maternal-Fetal Transfer of Thyroxine in Congenital Hypothyroidism Due to a Total Organification Defect or Thyroid Agenesis

Vulsma, T., Gons, M. H., & de Vijlder, J. J. M. (1989) · New England Journal of Medicine · doi:10.1056/nejm198907063210103 · Cited by 795

Principles of Neural Science

Rothwell, J. (1982) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.45.5.476 · Cited by 744

Maternal and Fetal Thyroid Function

Epstein, F. H., Burrow, G. N., Fisher, D. A., & Larsen, P. R. (1994) · New England Journal of Medicine · doi:10.1056/nejm199410203311608 · Cited by 720

The role of thyroid hormones in prenatal and neonatal neurological development--current perspectives

Porterfield, S. P. (1993) · Endocrine Reviews · doi:10.1210/er.14.1.94 · Cited by 672

Relationships between Circulating and Intracellular Thyroid Hormones: Physiological and Clinical Implications*

LARSEN, P. R., SILVA, J. E., & KAPLAN, M. M. (1981) · Endocrine Reviews · doi:10.1210/edrv-2-1-87 · Cited by 546

Spatial and temporal expression of alpha- and beta-thyroid hormone receptor mRNAs, including the beta 2-subtype, in the developing mammalian nervous system

Bradley, D., Towle, H., & Young, W. (1992) · The Journal of Neuroscience · doi:10.1523/jneurosci.12-06-02288.1992 · Cited by 538

Is Neuropsychological Development Related to Maternal Hypothyroidism or to Maternal Hypothyroxinemia?1

Morreale de Escobar, G., Jesús Obregón, M., & Escobar del Rey, F. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.11.6961 · Cited by 538

Molecular Basis of Thyroid Hormone-Dependent Brain Development*

Oppenheimer, J. H., & Schwartz, H. L. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.4.0309 · Cited by 517

The Ca2+–calmodulin-dependent protein kinase cascade

Soderling, T. R. (1999) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(99)01383-3 · Cited by 509

Disruption of the nuclear hormone receptor RORα in staggerer mice

Hamilton, B. A., Frankel, W. N., Kerrebrock, A. W., Hawkins, T. L., FitzHugh, W., Kusumi, K., Russell, L. B., Mueller, K. L., van Berkel, V., Birren, B. W., et al. (1996) · Nature · doi:10.1038/379736a0 · Cited by 492

Functional and structural diversity of the human Dickkopf gene family

Krupnik, V. E., Sharp, J. D., Jiang, C., Robison, K., Chickering, T. W., Amaravadi, L., Brown, D. E., Guyot, D., Mays, G., Leiby, K., et al. (1999) · Gene · doi:10.1016/s0378-1119(99)00365-0 · Cited by 489

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors.

Giguère, V, Tini, M., Flock, G., Ong, E., Evans, R. M., & Otulakowski, G. (1994) · Genes & Development · doi:10.1101/gad.8.5.538 · Cited by 486

NEUROLOGICAL DAMAGE TO THE FETUS RESULTING FROM SEVERE IODINE DEFICIENCY DURING PREGNANCY

Pharoah, P. O. D., Buttfield, I. H., & Hetzel, B. S. (1971) · The Lancet · doi:10.1016/s0140-6736(71)91040-3 · Cited by 467

Thyroid hormone metabolism

HENNEMANN, G. (1986) · M. Dekker eBooks · Cited by 453

Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation

Gothe, S., Wang, Z., Ng, L., Kindblom, J. M., Barros, A. C., Ohlsson, C., Vennstrom, B., & Forrest, D. (1999) · Genes & Development · doi:10.1101/gad.13.10.1329 · Cited by 445

Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function.

Forrest, D., Hanebuth, E., Smeyne, R. J., Everds, N., Stewart, C. L., Wehner, J. M., & Curran, T. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00664.x · Cited by 440

Abnormal Cerebellar Development and Foliation in BDNF−/− Mice Reveals a Role for Neurotrophins in CNS Patterning

Schwartz, P. M., Borghesani, P. R., Levy, R. L., Pomeroy, S. L., & Segal, R. A. (1997) · Neuron · doi:10.1016/s0896-6273(00)80938-1 · Cited by 437

Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing

Koenig, R. J., Lazar, M. A., Hodin, R. A., Brent, G. A., Larsen, P. R., Chin, W. W., & Moore, D. D. (1989) · Nature · doi:10.1038/337659a0 · Cited by 430

Thyroid hormone receptor α isoforms generated by alternative splicing differentially activate myosin HC gene transcription

Izumo, S., & Mahdavi, V. (1988) · Nature · doi:10.1038/334539a0 · Cited by 420

Thyroid hormones and brain development

Bernal, J., & Nunez, J. (1995) · European Journal of Endocrinology · doi:10.1530/eje.0.1330390 · Cited by 418

Maturation of the Secretion of Thyroid Hormone and Thyroid-Stimulating Hormone in the Fetus

Thorpe-Beeston, J. G., Nicolaides, K. H., Felton, C. V., Butler, J., & McGregor, A. M. (1991) · New England Journal of Medicine · doi:10.1056/nejm199102213240805 · Cited by 406

Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues.

Croteau, W., Davey, J. C., Galton, V. A., & St Germain, D. L. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118806 · Cited by 378

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

Sap, J., Muñoz, A., Schmitt, J., Stunnenberg, H., & Vennström, B. (1989) · Nature · doi:10.1038/340242a0 · Cited by 378

Targeted Disruption of the Type 2 Selenodeiodinase Gene (DIO 2) Results in a Phenotype of Pituitary Resistance to T4

Schneider, M. J., Fiering, S. N., Pallud, S. E., Parlow, A. F., St. Germain, D. L., & Galton, V. A. (2001) · Molecular Endocrinology · doi:10.1210/mend.15.12.0740 · Cited by 376

The type 2 iodothyronine deiodinase is expressed primarily in glial cells in the neonatal rat brain

Guadaño-Ferraz, A., Obregón, M. J., Germain, D. L. S., & Bernal, J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10391 · Cited by 372

Brain-endocrine interaction

Knigge, K. M., Scott, D. E., & Weindl, A. (1972) · KARGER eBooks · Cited by 372

The Relation of Transient Hypothyroxinemia in Preterm Infants to Neurologic Development at Two Years of Age

Reuss, M. L., Paneth, N., Pinto-Martin, J. A., Lorenz, J. M., & Susser, M. (1996) · New England Journal of Medicine · doi:10.1056/nejm199603283341303 · Cited by 369

Effects of Maternal Hypothyroidism on the Weight and Thyroid Hormone Content of Rat Embryonic Tissues, before and after Onset of Fetal Thyroid Function*

ESCOBAR, G. M. D., PASTOR, R., OBREGON, M. J., & REY, F. E. D. (1985) · Endocrinology · doi:10.1210/endo-117-5-1890 · Cited by 361

The T3Ralpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production

Fraichard, A. (1997) · The EMBO Journal · doi:10.1093/emboj/16.14.4412 · Cited by 349

Neuronal migration disorders: from genetic diseases to developmental mechanisms

Gleeson, J. G., & Walsh, C. A. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01607-6 · Cited by 344

The Deiodinase Family of Selenoproteins

GERMAIN, D. L. S., & GALTON, V. A. (1997) · Thyroid · doi:10.1089/thy.1997.7.655 · Cited by 342

An Analysis of the Sources and Quantity of 3,5,3′-Triiodothyronine Specifically Bound to Nuclear Receptors in Rat Cerebral Cortex and Cerebellum*

CRANTZ, F. R., SILVA, J. E., & LARSEN, P. R. (1982) · Endocrinology · doi:10.1210/endo-110-2-367 · Cited by 340

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit.

Lazar, M. A., Hodin, R. A., Darling, D. S., & Chin, W. W. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.3.1128 · Cited by 316

Five mouse tubulin isotypes and their regulated expression during development.

Lewis, S. A., Lee, M. G., & Cowan, N. J. (1985) · The Journal of cell biology · doi:10.1083/jcb.101.3.852 · Cited by 314

Neurobehavioral teratology

Dobbing, J. (1984) · Early Human Development · doi:10.1016/0378-3782(84)90130-0 · Cited by 306

Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone

Tu, H. M., Kim, S.-W., Salvatore, D., Bartha, T., Legradi, G., Larsen, P. R., & Lechan, R. M. (1997) · Endocrinology · doi:10.1210/endo.138.8.5318 · Cited by 302

Prostaglandin D synthase: Structure and function

(2000) · Vitamins & Hormones · doi:10.1016/s0083-6729(00)58022-4 · Cited by 299

Functions of Thyroid Hormone Receptors in Mice

Forrest, D., & Vennström, B. (2000) · Thyroid · doi:10.1089/thy.2000.10.41 · Cited by 299

Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats.

Strait, K. A., Schwartz, H. L., Perez-Castillo, A., & Oppenheimer, J. H. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)86977-0 · Cited by 293

Effects of Thyroxine Supplementation on Neurologic Development in Infants Born at Less Than 30 Weeks' Gestation

van Wassenaer, A. G., Kok, J. H., de Vijlder, J. J. M., Briët, J. M., Smit, B. J., Tamminga, P., van Baar, A., Dekker, F. W., & Vulsma, T. (1997) · New England Journal of Medicine · doi:10.1056/nejm199701023360104 · Cited by 292

Cloning and Characterization of Two Novel Thyroid Hormone Receptor β Isoforms

Williams, G. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.22.8329-8342.2000 · Cited by 284

The Role of Thyroid Hormones in Prenatal and Neonatal Neurological Development—Current Perspectives

PORTERFIELD, S. P., & HENDRICH, C. E. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-1-94 · Cited by 283

The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype.

Wang, D., Villasante, A., Lewis, S. A., & Cowan, N. J. (1986) · The Journal of cell biology · doi:10.1083/jcb.103.5.1903 · Cited by 279

ONTOGENESIS OF THE NUCLEAR 3,5,3′-TRIIODOTHYRONINE RECEPTOR IN THE HUMAN FETAL BRAIN

BERNAL, J., & PEKONEN, F. (1984) · Endocrinology · doi:10.1210/endo-114-2-677 · Cited by 275

Involvement of neurogranin in the modulation of calcium/calmodulin-dependent protein kinase II, synaptic plasticity, and spatial learning: A study with knockout mice

Pak, J. H., Huang, F. L., Li, J., Balschun, D., Reymann, K. G., Chiang, C., Westphal, H., & Huang, K.-P. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.210184697 · Cited by 269

Thyroid Hormone Metabolism

Kaptein, E. M., Hays, M. T., & Ferguson, D. C. (1994) · Veterinary Clinics of North America: Small Animal Practice · doi:10.1016/s0195-5616(94)50051-2 · Cited by 267

Congenital Hypothyroidism: Etiologies, Diagnosis, and Management

LaFRANCHI, S. (1999) · Thyroid · doi:10.1089/thy.1999.9.735 · Cited by 259

Components of a Calmodulin-dependent Protein Kinase Cascade

Anderson, K. A., Means, R. L., Huang, Q.-H., Kemp, B. E., Goldstein, E. G., Selbert, M. A., Edelman, A. M., Fremeau, R. T., & Means, A. R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.48.31880 · Cited by 253

Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus

Miyajima, N., Horiuchi, R., Shibuya, Y., Fukushige, S.-I., Matsubara, K.-I., Toyoshima, K., & Yamamoto, T. (1989) · Cell · doi:10.1016/0092-8674(89)90169-4 · Cited by 249

Expression Profiles of the Three Iodothyronine Deiodinases, D1, D2, and D3, in the Developing Rat1

Bates, J. M., St. Germain, D. L., & Galton, V. A. (1999) · Endocrinology · doi:10.1210/endo.140.2.6537 · Cited by 243

Detection of thyroid hormones in human embryonic cavities during the first trimester of pregnancy.

Contempré, B., Jauniaux, E., Calvo, R., Jurkovic, D., Campbell, S., & de Escobar, G. M. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.77.6.8263162 · Cited by 241

Frontiers in Thyroidology: Volume 1

(1986) · Springer eBooks · doi:10.1007/978-1-4684-5260-0 · Cited by 234

Neonatal Screening for Congenital Hypothyroidism Results and Perspectives

Delange, F. (1997) · Hormone Research · doi:10.1159/000185485 · Cited by 221

The Relation between Neonatal Thyroxine Levels and Neurodevelopmental Outcome at Age 5 and 9 Years in a National Cohort of Very Preterm and/or Very Low Birth Weight Infants

Den Ouden, A. L., Kok, J. H., Verkerk, P. H., Brand, R., & Verloove-Vanhorick, S. P. (1996) · Pediatric Research · doi:10.1203/00006450-199601000-00021 · Cited by 219

The multitubulin hypothesis revisited: what have we learned?

Cleveland, D. W. (1987) · The Journal of cell biology · doi:10.1083/jcb.104.3.381 · Cited by 214

RC3/neurogranin, a postsynaptic calpacitin for setting the response threshold to calcium influxes

Gerendasy, D. D., & Gregor Sutcliffe, J. (1997) · Molecular Neurobiology · doi:10.1007/bf02740632 · Cited by 212

Alpha and beta thyroid hormone receptor (TR) gene expression during auditory neurogenesis: evidence for TR isoform-specific transcriptional regulation in vivo.

Bradley, D. J., Towle, H. C., & Young, W. S. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.2.439 · Cited by 212

Timing of Neuroblast Multiplication in Developing Human Brain

DOBBING, J., & SANDS, J. (1970) · Nature · doi:10.1038/226639a0 · Cited by 207

Cerebral cortex responds rapidly to thyroid hormones

Leonard, J. L., Kaplan, M. M., Visser, T. J., Silva, J. E., & Larsen, P. R. (1981) · Science · doi:10.1126/science.7291997 · Cited by 206

Neurotrophins promote the survival and development of neurons in the cerebellum of hypothyroid rats in vivo.

Neveu, I., & Arenas, E. (1996) · The Journal of cell biology · doi:10.1083/jcb.133.3.631 · Cited by 206

Regional Expression of the Type 3 Iodothyronine Deiodinase Messenger Ribonucleic Acid in the Rat Central Nervous System and Its Regulation by Thyroid Hormone

Tu, H. M., Légrádi, G., Bartha, T., Salvatore, D., Lechan, R. M., & Larsen, P. R. (1999) · Endocrinology · doi:10.1210/en.140.2.784 · Cited by 198

The effect of neonatal thyroidectomy on myelination in the rat brain

Balázs, R., Brooksbank, B. W. L., Davison, A. N., Eayrs, J. T., & Wilson, D. A. (1969) · Brain Research · doi:10.1016/0006-8993(69)90321-7 · Cited by 197

Outcome of severe congenital hypothyroidism: closing the developmental gap with early high dose levothyroxine treatment

Dubuis, J. M. (1996) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.81.1.222 · Cited by 194

Independent Expression of the α and β c-erb A Genes in Developing Rat Brain

Mellström, B., Naranjo, J. R., Santos, A., Gonzalez, A. M., & Bernal, J. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-9-1339 · Cited by 193

Thyroid Hormone-Responsive Genes in Developing Cerebellum Include a Novel Synaptotagmin and a hairless Homolog

Thompson, C. C. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-24-07832.1996 · Cited by 191

Type 3 lodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme.

Salvatore, D., Low, S. C., Berry, M., Maia, A. L., Harney, J. W., Croteau, W., St Germain, D. L., & Larsen, P. R. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118299 · Cited by 187

The type 2 and type 3 iodothyronine deiodinases play important roles in coordinating development in rana catesbeiana tadpoles

Becker, K. B., Stephens, K. C., Davey, J. C., Schneider, M. J., & Galton, V. A. (1997) · Endocrinology · doi:10.1210/endo.138.7.5272 · Cited by 185

l-THYROXINE AND 3,5,3’-TRII000-l-THYRONINE IN RAT EMBRYOS BEFORE ONSET OF FETAL THYROID FUNCTION.

OBREGON, M. J., MALLOL, J., PASTOR, R., ESCOBAR, G. M. D., & REY, F. E. D. (1984) · Endocrinology · doi:10.1210/endo-114-1-305 · Cited by 184

Expression of Type 2 Iodothyronine Deiodinase in Hypothyroid Rat Brain Indicates an Important Role of Thyroid Hormone in the Development of Specific Primary Sensory Systems

Guadaño-Ferraz, A., Escámez, M. J., Rausell, E., & Bernal, J. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-09-03430.1999 · Cited by 183

Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation

Lindholm, D., Castrén, E., Tsoulfas, P., Kolbeck, R., Berzaghi, M. D. P., Leingärtner, A., Heisenberg, C., Tessarollo, L., Parada, L., Thoenen, H., et al. (1993) · The Journal of cell biology · doi:10.1083/jcb.122.2.443 · Cited by 181

The Early Ontogenesis of Thyroid Hormone Receptor in the Rat Fetus*

PEREZ-CASTILLO, A., BERNAL, J., FERREIRO, B., & PANS, T. (1985) · Endocrinology · doi:10.1210/endo-117-6-2457 · Cited by 177

Identification of Transcripts Initiated from an Internal Promoter in the c-erbAα Locus That Encode Inhibitors of Retinoic Acid Receptor-α and Triiodothyronine Receptor Activities

Chassande, O., Fraichard, A., Gauthier, K., Flamant, F., Legrand, C., Savatier, P., Laudet, V., & Samarut, J. (1997) · Molecular Endocrinology · doi:10.1210/mend.11.9.9972 · Cited by 177

Thyroxine transport in choroid plexus.

Dickson, P. W., Aldred, A. R., Menting, J. G., Marley, P. D., Sawyer, W. H., & Schreiber, G. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47880-5 · Cited by 175

Nutritional and Hormonal Regulation of Thyroid Hormone Deiodinases

Larsen, P. R., & Berry, M. J. (1995) · Annual Review of Nutrition · doi:10.1146/annurev.nu.15.070195.001543 · Cited by 175

Thyroid Hormone Regulates reelin and dab1 Expression During Brain Development

Alvarez-Dolado, M., Ruiz, M., Del Rı́o, J. A., Alcántara, S., Burgaya, F., Sheldon, M., Nakajima, K., Bernal, J., Howell, B. W., Curran, T., et al. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-16-06979.1999 · Cited by 171

Neonatal hypothyroidism affects the timely expression of myelin-associated glycoprotein in the rat brain.

Rodriguez-Peña, A., Ibarrola, N., Iñiguez, M. A., Muñoz, A., & Bernal, J. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116301 · Cited by 167

Ontogenesis of 3,5,3′-Triiodothyronine Receptors in Neonatal Rat Brain: Dissociation between Receptor Concentration and Stimulation of Oxygen Consumption by 3,5,3′-Triiodothyronine*

SCHWARTZ, H. L., & OPPENHEIMER, J. H. (1978) · Endocrinology · doi:10.1210/endo-103-3-943 · Cited by 164

Asymmetric Growth and Development of the Xenopus laevis Retina during Metamorphosis Is Controlled by Type III Deiodinase

Marsh-Armstrong, N., Huang, H., Remo, B. F., Liu, T. T., & Brown, D. D. (1999) · Neuron · doi:10.1016/s0896-6273(00)81034-x · Cited by 162

Metamorphosis is inhibited in transgenic Xenopus laevis tadpoles that overexpress type III deiodinase

Huang, H., Marsh-Armstrong, N., & Brown, D. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.3.962 · Cited by 162

TRANSFER OF THYROID HORMONE ACROSS THE HUMAN PLACENTA AT TERM*

WERNER, S. C. (1956) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-16-10-1392 · Cited by 161

NEUROLOGICAL SIGNS IN CONGENITAL IODINE‐DEFICIENCY DISORDER (ENDEMIC CRETINISM)

DeLong, G. R., Stanbury, J. B., & FIERRO-BENITEZ, R. (1985) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1985.tb04542.x · Cited by 156

Distinct functions for thyroid hormone receptors alpha and beta in brain development indicated by differential expression of receptor genes.

Forrest, D., Hallböök, F., Persson, H., & Vennström, B. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07947.x · Cited by 154

Ontogeny of Iodothyronine Deiodinases in Human Liver

Richard, K., Hume, R., Kaptein, E., Sanders, J. P., van Toor, H., de Herder, W. W., den Hollander, J. C., Krenning, E. P., & Visser, T. J. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.8.5032 · Cited by 154

Pregnant rat uterus expresses high levels of the type 3 iodothyronine deiodinase

Galton, V. A., Martinez, E., Hernández, A., Germain, E. A. S., Bates, J. M., & Germain, D. L. S. (1999) · Journal of Clinical Investigation · doi:10.1172/jci6073 · Cited by 152

Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing

Campos‐Barros, Á., Amma, L. L., Faris, J. S., Shailam, R., Kelley, M. W., & Forrest, D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1287 · Cited by 149

Effects of Neonatal Hypothyroidism on Rat Brain Gene Expression

Múñoz, A., Rodríguez‐Peña, A., Pérez‐Castillo, A., Ferreiro, B., Sutcliffe, J. G., & Bernal, J. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-2-273 · Cited by 148

Type II and type III deiodinase activity in human placenta as a function of gestational age

Koopdonk-Kool, J. M., de Vijlder, J. J. M., Veenboer, G. J. M., Ris‐Stalpers, C., Kok, J. H., Vulsma, T., Boer, K., & Visser, T. J. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.6.8964844 · Cited by 146

The prenatal role of thyroid hormone evidenced by fetomaternal Pit-1 deficiency

de Zegher, F., Pernasetti, F. M., Vanhole, C., Devlieger, H., den Berghe, G. V., & MARTIAL, J. A. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.11.7593413 · Cited by 146

Neonatal Hypothyroxinemia: Effects of Iodine Intake and Premature Birth1

Segura, S. A., Escobar-Morreale, H. F., Quero, J., Durán, S., Presas, M. J., Herruzo, R., & de Escobar, G. M. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.6.4019 · Cited by 141

Thyroxine transport to the brain: role of protein synthesis by the choroid plexus

Southwell, B. R. (1993) · Endocrinology · doi:10.1210/en.133.5.2116 · Cited by 140

Cell-specific effects of thyroid hormone on RC3/neurogranin expression in rat brain

Iñiguez, M. A., de Lecea, L., Guadaño‐Ferraz, A., Morte, B., Gerendasy, D. D., Sutcliffe, J. G., & Bernal, J. (1996) · Endocrinology · doi:10.1210/endo.137.3.8603571 · Cited by 137

Role of transthyretin in the transport of thyroxine from the blood to the choroid plexus, the cerebrospinal fluid, and the brain

Chanoine, J., Alex, S., Fang, S. L., Stone, S., Leonard, J. L., Köhrle, J., & Braverman, L. E. (1992) · Endocrinology · doi:10.1210/endo.130.2.1733735 · Cited by 136

Developmental Changes in Rat Brain 5′-Deiodinase and Thyroid Hormones during the Fetal Period: The Effects of Fetal Hypothyroidism and Maternal Thyroid Hormones

de Oña, C. R., Obregón, M.-J., del Rey, F. E., & de Escobar, G. M. (1988) · Pediatric Research · doi:10.1203/00006450-198811000-00010 · Cited by 132

Maturational Patterns of Iodothyronine Phenolic and Tyrosyl Ring Deiodinase Activities in Rat Cerebrum, Cerebellum, and Hypothalamus

Kaplan, M. M., & Yaskoski, K. A. (1981) · Journal of Clinical Investigation · doi:10.1172/jci110136 · Cited by 129

Three‐dimensional structural organization of layer I of the human cerebral cortex: A golgi study

Marín‐Padilla, M. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902990107 · Cited by 128

Regulation of thyroid hormone metabolism during fetal development

Darras, V., Hume, R., & Visser, T. J. (1999) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(99)00088-x · Cited by 128

Basic Transcription Element-binding Protein (BTEB) Is a Thyroid Hormone-regulated Gene in the Developing Central Nervous System

Denver, R. J., Ouellet, L., Furling, D., Kobayashi, A., Fujii‐Kuriyama, Y., & Puymirat, J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23128 · Cited by 128

Human carboxyl-terminal variant of alpha-type c-erbA inhibits trans-activation by thyroid hormone receptors without binding thyroid hormone.

Lazar, M. A., Hodin, R. A., & Chin, W. W. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.20.7771 · Cited by 127

Maternal Hypothyroidism and Fetal Development

Utiger, R. D. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908193410809 · Cited by 127

Thyroid hormones, the brain, and affective disorders.

Joffe, R. T., & Sokolov, S. T. H. (1994) · PubMed · Cited by 126

Hypothyroidism coordinately and transiently affects myelin protein gene expression in most rat brain regions during postnatal development

Ibarrola, N., & Rodríguez‐Peña, A. (1997) · Brain Research · doi:10.1016/s0006-8993(96)01480-1 · Cited by 124

Thyroid Hormone Receptor Gene Expression in First Trimester Human Fetal Brain

Iskaros, J., Pickard, M. R., Evans, I. M., Sinha, A., Hardiman, P., & Ekins, R. P. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6766 · Cited by 123

The Expression Pattern of Thyroid Hormone Response Genes in Remodeling Tadpole Tissues Defines Distinct Growth and Resorption Gene Expression Programs

Berry, D. L., Rose, C. S., Remo, B. F., & Brown, D. D. (1998) · Developmental Biology · doi:10.1006/dbio.1998.8975 · Cited by 122

Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbAα orphan receptor

Chomez, P., Neveu, I., Mansén, A., Kiesler, E., Larsson, L., Vennström, B., & Arenas, E. (2000) · Development · doi:10.1242/dev.127.7.1489 · Cited by 118

Transport of iodothyronines from bloodstream to brain: contributions by blood:brain and choroid plexus:cerebrospinal fluid barriers

Dratman, M. B., Crutchfield, F. L., & Schoenhoff, M. B. (1991) · Brain Research · doi:10.1016/0006-8993(91)90194-z · Cited by 117

CONTRIBUTION OF MATERNAL THYROXINE TO FETAL THYROXINE POOLS IN NORMAL RATS NEAR TERM

de Escobar, G. M., Calvo, R. M., Obregón, M.-J., & del Rey, F. E. (1990) · Endocrinology · doi:10.1210/endo-126-5-2765 · Cited by 116

Rhes: A striatal-specific Ras homolog related to Dexras1

Falk, J. D., Vargiu, P., Foye, P. E., Usui, H., Perez, J., Danielson, P. E., Lerner, D. L., Bernal, J., & Sutcliffe, J. G. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990915)57:6<782::aid-jnr3>3.0.co;2-9 · Cited by 115

Developing cholinergic basal forebrain neurons are sensitive to thyroid hormone

Gould, E., & Ll, B. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-09-03347.1989 · Cited by 114

Maternal Autoimmunization to Thyroid as a Probable Cause of Athyrotic Cretinism

Blizzard, R. M., Chandler, R. W., Landing, B. H., Pettit, M. D., & West, C. D. (1960) · New England Journal of Medicine · doi:10.1056/nejm196008182630702 · Cited by 114

Beta 1 isoform-specific regulation of a triiodothyronine-induced gene during cerebellar development.

Strait, K. A., Zou, L., & Oppenheimer, J. H. (1992) · Molecular Endocrinology · doi:10.1210/mend.6.11.1282672 · Cited by 111

Estimation of Nuclear Thyroid Hormone Receptor Saturation in Human Fetal Brain and Lung During Early Gestation*

Ferreiro, B., Bernal, J., GOODYER, G., & BRANCHARD, C. L. (1988) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-67-4-853 · Cited by 111

Congenital Hypothyroidism

Hughes, I. A. (1984) · Archives of Disease in Childhood · doi:10.1136/adc.59.7.697-a · Cited by 110

Fetal and Maternal Thyroid Hormones

de Escobar, G. M., Obregón, M. J., & del Rey, F. E. (1987) · Hormone Research · doi:10.1159/000180681 · Cited by 109

Dendritic spine density of adult hippocampal pyramidal cells is sensitive to thyroid hormone

Gould, E., Allan, M. D., & McEwen, B. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90884-e · Cited by 109

Thyroid hormone and estrogen interact to regulate behavior.

Dellovade, T. L., Zhu, Y. S., Krey, L., & Pfaff, D. W. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.22.12581 · Cited by 108

Cellular organization of the lateral and postinfundibular regions of the median eminence in the rat

Rodr�guez, E. M., Gonz�lez, C. B., & Delannoy, L. (1979) · Cell and Tissue Research · doi:10.1007/bf00236998 · Cited by 108

Thyroid hormone regulation of RC3, a brain-specific gene encoding a protein kinase-C substrate

Iñiguez, M. A., Rodríguez‐Peña, A., Ibarrola, N., Aguilera, M., Múñoz, A., & Bernal, J. (1993) · Endocrinology · doi:10.1210/endo.133.2.8344193 · Cited by 107

Thyroid Hormones and the Developing Brain

de Escobar, G. M. (1986) · Springer eBooks · doi:10.1007/978-1-4684-5260-0_2 · Cited by 107

Thyroxine transport to the brain: role of protein synthesis by the choroid plexus

Southwell, B. R., Duan, W., Alcorn, D., Brack, C., Richardson, S. J., Köhrle, J., & Schreiber, G. (1993) · Endocrinology · doi:10.1210/endo.133.5.8404661 · Cited by 105

Maternal to fetal thyroxine transmission in the human term placenta is limited by inner ring deiodination

Mortimer, R. H., Galligan, J., Cannell, G. R., Addison, R. S., & Roberts, M. S. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.6.8964859 · Cited by 105

Expression of neurotrophins and the trk family of neurotrophin receptors in normal and hypothyroid rat brain

Álvarez‐Dolado, M., Iglesias, T., Rodríguez‐Peña, A., Bernal, J., & Múñoz, A. (1994) · Molecular Brain Research · doi:10.1016/0169-328x(94)90007-8 · Cited by 102

Adult rat brain is sensitive to thyroid hormone. Regulation of RC3/neurogranin mRNA.

Iñiguez, M. A., Rodríguez‐Peña, A., Ibarrola, N., de Escobar, G. M., & Bernal, J. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115894 · Cited by 101

Maturation of the corpus callosum of the rat: II. Influence of thyroid hormones on the number and maturation of axons

Gravel, C., Sasseville, R., & Hawkes, R. B. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902910110 · Cited by 100

Selenium deficiency and thyroid fibrosis. A key role for macrophages and transforming growth factor β (TGF-β)

Contempré, B., Moine, O. L., Dumont, J. E., Denef, J., & Many, M. (1996) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(96)03921-4 · Cited by 100

Effects of selenium deficiency on thyroid necrosis, fibrosis and proliferation: a possible role in myxoedematous cretinism

Contempré, B., Dumont, J. E., Denel, J.-F., & Many, M. (1995) · European Journal of Endocrinology · doi:10.1530/eje.0.1330099 · Cited by 100

Role of thyroid hormones in the maturation of interhemispheric connections in rats

Berbel, P. J., Guadaño‐Ferraz, A., Jeréz, A. A., & Cerezo, J. R. (1994) · Behavioural Brain Research · doi:10.1016/0166-4328(94)90114-7 · Cited by 96

The regional hypothalamic distribution of type II 5′-monodeiodinase in euthyroid and hypothyroid rats

Riskind, P. N., Kolodny, J. M., & Reed Larsen, P. (1987) · Brain Research · doi:10.1016/0006-8993(87)90260-5 · Cited by 92

Thyroid hormone metabolism in a transthyretin-null mouse strain

Palha, J. A., Episkopou, V., Maeda, S., 島田, 和., Gottesman, M. E., & Saraiva, M. J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)30107-1 · Cited by 91

The Human RC3 Gene Homolog, NRGN Contains a Thyroid Hormone-Responsive Element Located in the First Intron

de Arrieta, C. M., Morte, B., Coloma, A., & Bernal, J. (1999) · Endocrinology · doi:10.1210/endo.140.1.6461 · Cited by 91

Organization of Auditory Callosal Connections in Hypothyroid Adult Rats

Berbel, P. J., Guadaño‐Ferraz, A., Martínez, M., Quiles, J. A., Balboa, R., & Innocenti, G. M. (1993) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1993.tb00214.x · Cited by 90

Overexpression of the beta 1 thyroid receptor induces differentiation in neuro-2a cells.

Lebel, J., Dussault, J. H., & Puymirat, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.7.2644 · Cited by 89

Outer Ring Iodothyronine Deiodinases and Thyroid Hormone Economy: Responses to Iodine Deficiency in the Rat Fetus and Neonate

Obregón, M.-J., de Oña, C. R., CALVO, R., del Rey, F. E., & de Escobar, G. M. (1991) · Endocrinology · doi:10.1210/endo-129-5-2663 · Cited by 89

Promoter-Specific Regulation of the Brain-Derived Neurotropic Factor Gene by Thyroid Hormone in the Developing Rat Cerebellum1

Koibuchi, N., Fukuda, H., & Chin, W. W. (1999) · Endocrinology · doi:10.1210/endo.140.9.6997 · Cited by 87

Hormone synthesis and storage in the thyroid of human preterm and term newborns: Effect of thyroxine treatment

van den Hove, M.-F., Beckers, C., Devlieger, H., de Zegher, F., & Nayer, P. D. (1999) · Biochimie · doi:10.1016/s0300-9084(99)80111-4 · Cited by 85

Immunocytochemical delineation of thyroid hormone receptor beta 2-like immunoreactivity in the rat central nervous system.

Lechan, R. M., Qi, Y., Berrodin, T. J., Davis, K. D., Schwartz, H. L., Strait, K. A., Oppenheimer, J. H., & Lazar, M. A. (1993) · Endocrinology · doi:10.1210/endo.132.6.7684976 · Cited by 85

The Cyclin-dependent Kinase Inhibitor p27Kip1 Is Involved in Thyroid Hormone-mediated Neuronal Differentiation

Pérez-Juste, G., & Aranda, A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.8.5026 · Cited by 84

Thyroid Hormone Regulates the Expression of Laminin in the Developing Rat Cerebellum1

Farwell, A. P., & Dubord, S. (1999) · Endocrinology · doi:10.1210/endo.140.9.7007 · Cited by 83

Investigations on myelination in vitro. Regulation of sulfolipid synthesis by thyroid hormone in cultures of dissociated brain cells from embryonic mice.

Bhat, N. R., Rao, G. S., & Pieringer, R. A. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69944-8 · Cited by 82

Effects of Maternal Iodine Deficiency on the L-Thyroxine and 3,5,3′-Triiodo-L-Thyronine Contents of Rat Embryonic Tissues before and after Onset of Fetal Thyroid Function*

del Rey, F. E., PASTOR, R., Mallol, J., & de Escobar, G. M. (1986) · Endocrinology · doi:10.1210/endo-118-4-1259 · Cited by 82

Splicing of juvenile and adult tau mRNA variants is regulated by thyroid hormone.

Aniello, F., Couchie, D., Bridoux, A.-M., Gripois, D., & Nunez, J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.9.4035 · Cited by 82

Thyroxine treatment and recovery of hypothyroidism-induced pyramidal cell damage

Ruiz‐Marcos, A., Sánchez-Toscano, F., Obregón, M.-J., del Rey, F. E., & de Escobar, G. M. (1982) · Brain Research · doi:10.1016/0006-8993(82)90530-3 · Cited by 81

Cortical development: Receiving Reelin

Gilmore, E. C., & Herrup, K. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00332-8 · Cited by 81

Biological activities of thyroid hormone receptors

Munoz, A., & Bernal, J. (1997) · European Journal of Endocrinology · doi:10.1530/eje.0.1370433 · Cited by 81

Thyroid hormone‐dependent transcriptional repression of neural cell adhesion molecule during brain maturation.

Iglesias, T., Caubín, J., Stunnenberg, H. G., Zaballos, Á., Bernal, J., & Múñoz, A. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00805.x · Cited by 80

Transcriptional induction of RC3/neurogranin by thyroid hormone: differential neuronal sensitivity is not correlated with thyroid hormone receptor distribution in the brain

Guadaño‐Ferraz, A., Escamez, M. J., Morte, B., Vargiu, P., & Bernal, J. (1997) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00119-8 · Cited by 79

Reversible morphological alterations of cortical neurons in juvenile and adult hypothyroidism in the rat

Ruiz‐Marcos, A., Sánchez-Toscano, F., Escobar, F., Rey, D., & de Escobar, G. M. (1980) · Brain Research · doi:10.1016/0006-8993(80)90674-5 · Cited by 79

Hormone delivery systems to the brain - transthyretin

Schreiber, G., Southwell, B. R., & Richardson, S. J. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1211332 · Cited by 79

Hypothyroxinemia in Premature Infants: Is Thyroxine Treatment Necessary?

Fisher, D. A. (1999) · Thyroid · doi:10.1089/thy.1999.9.715 · Cited by 77

B Cell Antigen Receptor Signaling Induces the Formation of Complexes Containing the Crk Adapter Proteins

Ingham, R. J., Krebs, D. L., Barbazuk, S. M., Turck, C. W., Hirai, H., Matsuda, M., & Gold, M. R. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.50.32306 · Cited by 76

Type 3 Iodothyronine Deiodinase Is Selectively Expressed in Areas Related to Sexual Differentiation in the Newborn Rat Brain

Escamez, M. J., Guadaño‐Ferraz, A., Cuadrado, A., & Bernal, J. (1999) · Endocrinology · doi:10.1210/endo.140.11.7244 · Cited by 76

Thyroid Hormones Regulate -Amyloid Gene Splicing and Protein Secretion in Neuroblastoma Cells

Latasa, M. J., Belandia, B., & Pascual, A. (1998) · Endocrinology · doi:10.1210/endo.139.6.6033 · Cited by 76

Thyroid Hormone-independent Interaction between the Thyroid Hormone Receptor β2 Amino Terminus and Coactivators

Grasemann, C., Zanger, K., Hashimoto, K., Cohen, R., Hollenberg, A. N., & Wondisford, F. E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.3.1787 · Cited by 76

Differential expression of thyroid hormone receptor isoforms in neurons and astroglial cells

Leonard, J. L., Farwell, A. P., Yen, P. M., Chin, W. W., & Stula, M. (1994) · Endocrinology · doi:10.1210/endo.135.2.8033801 · Cited by 75

The 3′-Untranslated Region of Human Type 2 Iodothyronine Deiodinase mRNA Contains a Functional Selenocysteine Insertion Sequence Element

Buettner, C., Harney, J. W., & Larsen, P. R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.50.33374 · Cited by 74

ROR Gene Expression in the Perinatal Rat Cerebellum: Ontogeny and Thyroid Hormone Regulation

Koibuchi, N., & Chin, W. W. (1998) · Endocrinology · doi:10.1210/endo.139.5.6013 · Cited by 73

Acidosis has no effect on the ATP cost of contraction in cat fast- and slow-twitch skeletal muscles

Harkema, S. J., Adams, G. R., & Meyer, R. A. (1997) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1997.272.2.c485 · Cited by 73

Gene expression in the developing cerebellum during perinatal hypo- and hyperthyroidism

de Figueiredo, B. C., Almazán, G., Ma, Y., Tetzlaff, W., Miller, F. D., & Cuello, A. C. (1993) · Molecular Brain Research · doi:10.1016/0169-328x(93)90010-m · Cited by 72

Type II Iodothyronine 5'-Deiodination by Human and Rat Placenta in Vitro*

Kaplan, M. M., & Shaw, E. A. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-59-2-253 · Cited by 71

Maturation of the corpus callosum of the rat: I. Influence of thyroid hormones on the topography of callosal projections

Gravel, C., & Hawkes, R. B. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902910109 · Cited by 70

Transthyretin is not essential for thyroxine to reach the brain and other tissues in transthyretin-null mice

Palha, J. A., Hays, M. T., de Escobar, G. M., Episkopou, V., Gottesman, M. E., & Saraiva, M. J. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.3.e485 · Cited by 70

Thyroid hormone treatment alters phospholipid composition and membrane fluidity of rat brain mitochondria

Bangur, C. S., Howland, J. L., & Katyare, S. S. (1995) · Biochemical Journal · doi:10.1042/bj3050029 · Cited by 67

Thyroid hormone-regulated brain mitochondrial genes revealed by differential cDNA cloning.

Vega-Núñez, E., Menéndez-Hurtado, A., Garesse, R., Santos, Á., & Pérez‐Castillo, A. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118136 · Cited by 67

The Hypothyroxinemia of Prematurity

de Escobar, G. M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.2.4587-3 · Cited by 67

Uptake and Metabolism of Thyroid Hormones by the Rat Foetus in Early Pregnancy

Woods, R. J., Sinha, A., & Ekins, R. P. (1984) · Clinical Science · doi:10.1042/cs0670359 · Cited by 66

Developmental expression of tenascin-C is altered by hypothyroidism in the rat brain

Álvarez‐Dolado, M., González‐Sancho, J. M., Bernal, J., & Múñoz, A. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00511-3 · Cited by 65

Effects of thyroid hormone on synaptogenesis in the molecular layer of the developing rat cerebellum.

Vincent, J., Legrand, C., Rabié, A., & Legrand, J. (1982) · PubMed · Cited by 65

The development of auditory callosal connections in normal and hypothyroid rats

Lucio, R. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.4.303 · Cited by 62

Immunofluorescent localization of thyroid hormone receptor isoforms in glial cells of rat brain

Carlson, D. J., Strait, K. A., Schwartz, H. L., & Oppenheimer, J. H. (1994) · Endocrinology · doi:10.1210/endo.135.5.7525253 · Cited by 62

Thyroid Function in Premature Infants: The Hypothyroxinemia of Prematurity

Fisher, D. A. (1998) · Clinics in Perinatology · doi:10.1016/s0095-5108(18)31344-7 · Cited by 61

Rapid effects of adult-onset hypothyroidism on dendritic spines of pyramidal cells of the rat cerebral cortex

Ruiz‐Marcos, A., Abella, P. C., Garc�a, A. G., del Rey, F. E., & de Escobar, G. M. (1988) · Experimental Brain Research · doi:10.1007/bf00406617 · Cited by 60

Thyroxine values from newborn screening of 919 infants born before 29 weeks' gestation.

Reuss, M. L., Leviton, A., Paneth, N., & Susser, M. W. (1997) · American Journal of Public Health · doi:10.2105/ajph.87.10.1693 · Cited by 59

Regulation of the L1 Cell Adhesion Molecule by Thyroid Hormone in the Developing Brain

Álvarez‐Dolado, M., Cuadrado, A., Navarro‐Yubero, C., Sonderegger, P., Furley, A. J., Bernal, J., & Múñoz, A. (2000) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2000.0879 · Cited by 59

Investigations on Myelination In Vitro: Regulation of 2′,3′‐Cyclic Nucleotide 3′‐Phosphohydrolase by Thyroid Hormone in Cultures of Dissociated Brain Cells from Embryonic Mice

Bhat, N. R., Shanker, G., & Pieringer, R. A. (1982) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1982.tb12543.x · Cited by 58

Induction of 5‐Deiodinase Activity in Astroglial Cells by 12‐O‐Tetradecanoylphorbol 13‐Acetate and Fibroblast Growth Factors

Courtin, F., Liva, P., Gavaret, J. M., Toru‐Delbauffe, D., & Pierre, M. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb11399.x · Cited by 58

Differential effect of thyroid hormone on NGFI-A gene expression in developing rat brain

Mellström, B., Pipaón, C., Naranjo, J. R., Pérez‐Castillo, A., & Santos, Á. (1994) · Endocrinology · doi:10.1210/endo.135.2.8033806 · Cited by 58

Regulation by thyroid hormone of microtubule assembly and neuronal differentiation

Nunez, J., Couchie, D., Aniello, F., & Bridoux, A. M. (1991) · Neurochemical Research · doi:10.1007/bf00965840 · Cited by 56

Induction of type III‐deiodinase activity in astroglial cells by retinoids

Esfandiari, A., Gagelin, C., Gavaret, J., Pavelka, S., Lennon, A., Pierre, M., & Courtin, F. (1994) · Glia · doi:10.1002/glia.440110306 · Cited by 55

Effects of maternal iodine supplementation during pregnancy.

Pharoah, P. O. D., & Connolly, K. (1991) · Archives of Disease in Childhood · doi:10.1136/adc.66.1.145 · Cited by 55

Identification of the Mitochondrial NADH Dehydrogenase Subunit-3 as a Thyroid Hormone-Regulated Gene by Whole Genome PCR Analysis

Iglesias, T., Caubín, J., Zaballos, Á., et al. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1755 · Cited by 54

Maternal Hypothyroidism Selectively Affects the Expression of Neuroendocrine-Specific Protein A Messenger Ribonucleic Acid in the Proliferative Zone of the Fetal Rat Brain Cortex

Dowling, A. L. S., Iannacone, E. A., & Zoeller, R. T. (2001) · Endocrinology · doi:10.1210/endo.142.1.7871 · Cited by 53

Beta receptor isoforms are not essential for thyroid hormone-dependent acceleration of PCP-2 and myelin basic protein gene expression in the developing brains of neonatal mice

Sandhofer, C. R., Schwartz, H. L., Mariash, C. N., et al. (1998) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(98)00005-7 · Cited by 52

Tissue iodothyronine levels in fetuses of control and hypothyroid rats at 13 and 16 days gestation.

Porterfield, S. P., & Hendrich, C. E. (1992) · Endocrinology · doi:10.1210/endo.131.1.1611997 · Cited by 51

Chicken Ovalbumin Upstream Promoter-Transcription Factor (COUP-TF) Modulates Expression of the Purkinje Cell Protein-2 Gene

Anderson, G. W., Larson, R. J., Oas, D. R., Sandhofer, C. R., Schwartz, H. L., Mariash, C. N., & Oppenheimer, J. H. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.26.16391 · Cited by 51

Contribution from local conversion of thyroxine to 3,5,3'-triiodothyronine to intracellular 3,5,3'-triiodothyronine in several organs in hypothyroid rats at isotope equilibrium

van Doom, J., Roelfsema, F., & van der Heide, D. (1982) · Acta Endocrinologica · doi:10.1530/acta.0.1010386 · Cited by 50

Iodothyronine Deiodinase Activities in Fetal Rat Tissues at Several Levels of Iodine Deficiency: A Role for the Skin in 3,5,3'-Triiodothyronine Economy?

der Elst, J. P. S.-V., van der Heide, D., de Escobar, G. M., & Obregón, M.-J. (1998) · Endocrinology · doi:10.1210/endo.139.5.6002 · Cited by 50

Cloning of a 5.8 kb cDNA for a Mouse Type 2 Deiodinase

Davey, J. C., Schneider, M. J., Becker, K., & Galton, V. A. (1999) · Endocrinology · doi:10.1210/endo.140.2.6678 · Cited by 49

Orphan nuclear receptor RORα gene: isoform-specific spatiotemporal expression during postnatal development of brain

Sashihara, S., Felts, P. A., Waxman, S. G., & Matsui, T. (1996) · Molecular Brain Research · doi:10.1016/s0169-328x(96)00118-0 · Cited by 48

RORα Augments Thyroid Hormone Receptor-Mediated Transcriptional Activation*

Koibuchi, N., Liu, Y., Fukuda, H., et al. (1999) · Endocrinology · doi:10.1210/endo.140.3.6562 · Cited by 48

Studies of Nuclear 3,5,3′-Triiodothyronine Binding in Primary Cultures of Rat Brain*

KOLODNY, J. M., Leonard, J. L., Larsen, P. R., & Silva, J. E. (1985) · Endocrinology · doi:10.1210/endo-117-5-1848 · Cited by 45

Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation

Friesema, E. C., Grueters, A., Biebermann, H., Krude, H., von Moers, A., Reeser, M., Barrett, T. G., Mancilla, E. E., Svensson, J., Kester, M. H., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17226-7 · Cited by 709

A Novel Syndrome Combining Thyroid and Neurological Abnormalities Is Associated with Mutations in a Monocarboxylate Transporter Gene

Dumitrescu, A. M., Liao, X.-H., Best, T. B., Brockmann, K., & Refetoff, S. (2004) · The American Journal of Human Genetics · doi:10.1086/380999 · Cited by 706

Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings

Zoeller, R. T., & Rovet, J. (2004) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2004.01243.x · Cited by 605

The Thyroid‐Brain Interaction in Thyroid Disorders and Mood Disorders

Bauer, M., Goetz, T., Glenn, T., & Whybrow, P. C. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01774.x · Cited by 438

Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice

Dumitrescu, A. M., Liao, X.-H., Weiss, R. E., Millen, K., & Refetoff, S. (2006) · Endocrinology · doi:10.1210/en.2006-0390 · Cited by 318