Cited by 63Gut microbiota and healthProbiotics and Fermented FoodsMicrobial Metabolites in Food Biotechnology

Gut microbiome approaches to treat obesity in humans

Open access
Bianchi, Fernanda, Duque, Ana Luiza Rocha Faria, Saad, Susana Marta Isay, Sivieri, Katia·2019·Applied Microbiology and Biotechnology

Abstract

The rising worldwide prevalence of obesity has become a major concern having many implications for the public health and the economy. It is well known that many factors such as lifestyle, increased intake of foods high in fat and sugar and a host's genetic profile can lead to obesity. Besides these factors, recent studies have pointed to the gut microbiota composition as being responsible for the development of obesity. Since then, many efforts have been made to understand the link between the gut microbiota composition and obesity, as well as the role of food ingredients, such as pro- and prebiotics, in the modulation of the gut microbiota. Studies involving the gut microbiota composition of obese individuals are however still controversial, making it difficult to treat obesity. In this sense, this mini-review deals with obesity and the relationship with gut microbiota, summarising the principal findings on gut microbiome approaches for treating obesity in humans.

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Crossref · 10.1007/s00253-018-9570-8

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114 of 114 references verified0 citation errors · 0 not checkable

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Authors
Bianchi, F., Duque, A. L. R. F., Saad, S. M. I., & Sivieri, K.
Affiliations
  • Universidade Estadual Paulista (Unesp) (BR)
  • Universidade de São Paulo (BR)
Venue
Applied Microbiology and Biotechnology
Published
2018-12-16
Volume
103
Issue
3
Pages
1081-1094
ISSN
  • 0175-7598 (ISSN-L)
  • 1432-0614
OpenAlex
W2904810196
Cited by
63
References
114
Citations by year
2025: 8 · 2024: 8 · 2023: 9 · 2022: 11 · 2021: 14 · 2020: 10 · 2019: 3
FWCI
0.66
Type
journal article
Language
en
Open access
Locations
  • Applied Microbiology and Biotechnology (publishedVersion)
  • PubMed (publishedVersion)
  • UNESP Institutional Repository (São Paulo State University) (submittedVersion, other-oa)
Funders
Fundação de Amparo à Pesquisa do Estado de São Paulo ((2013/50506-8; 2015/13965-0; 2015/08228-6))
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
Keywords
obesity, gut microbiota, obesity treatment, prebiotics, probiotics, food ingredients, microbiota composition, obesity risk factors
MeSH terms
Gastrointestinal Microbiome, Fecal Microbiota Transplantation, Humans, Obesity, Exercise, Probiotics, Gastrointestinal Tract, Prebiotics

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