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Cited by 303

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Effects of β-alanine supplementation on exercise performance: a meta-analysis

Open access
Hobson, R. M., Saunders, B., Ball, G., Harris, R. C., Sale, C.·2012·Amino Acids
DOI 10.1007/s00726-011-1200-z
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Abstract

Due to the well-defined role of β-alanine as a substrate of carnosine (a major contributor to H+ buffering during high-intensity exercise), β-alanine is fast becoming a popular ergogenic aid to sports performance. There have been several recent qualitative review articles published on the topic, and here we present a preliminary quantitative review of the literature through a meta-analysis. A comprehensive search of the literature was employed to identify all studies suitable for inclusion in the analysis; strict exclusion criteria were also applied. Fifteen published manuscripts were included in the analysis, which reported the results of 57 measures within 23 exercise tests, using 18 supplementation regimes and a total of 360 participants [174, β-alanine supplementation group (BA) and 186, placebo supplementation group (Pla)]. BA improved (P=0.002) the outcome of exercise measures to a greater extent than Pla [median effect size (IQR): BA 0.374 (0.140-0.747), Pla 0.108 (-0.019 to 0.487)]. Some of that effect might be explained by the improvement (P=0.013) in exercise capacity with BA compared to Pla; no improvement was seen for exercise performance (P=0.204). In line with the purported mechanisms for an ergogenic effect of β-alanine supplementation, exercise lasting 60-240 s was improved (P=0.001) in BA compared to Pla, as was exercise of >240 s (P=0.046). In contrast, there was no benefit of β-alanine on exercise lasting <60 s (P=0.312). The median effect of β-alanine supplementation is a 2.85% (-0.37 to 10.49%) improvement in the outcome of an exercise measure, when a median total of 179 g of β-alanine is supplemented.

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Metadata

Authors
Hobson, R. M., Saunders, B., Ball, G., Harris, R. C., & Sale, C.
Venue
Amino Acids
Publisher
Springer Science and Business Media LLC
Published
2012-01-24
Volume
43
Issue
1
Pages
25-37
ISSN
  • 0939-4451 (ISSN-L)
  • 1438-2199
DOI
10.1007/s00726-011-1200-z
OpenAlex
W2113762370
Cited by
303
References
12
FWCI
2.84
Type
journal article
Language
en
Open access
hybrid

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