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Gene expression hallmarks of cellular ageing

Frenk, Stephen, Houseley, Jonathan·2018·Biogerontology
DOI 10.1007/s10522-018-9750-zPMC PMC6223719
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  • Age-associated epigenomic alterations can induce significant transcriptional drift and initiate cellular aging processes, implicating altered epigenetic signatures in aging pathophysiology and aging-related diseases.

    “In particular, age-associated epigenomic alterations can induce significant transcriptional drift and initiate cellular aging processes, implicating altered epigenetic signatures in aging pathophysiology and aging-related diseases.4,5”

    From TERT activation targets DNA methylation and multiple aging hallmarks (2024) · cites this paper as [4]

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Metadata

Authors
Frenk, S., & Houseley, J.
ORCID
Houseley, Jonathan
Venue
Biogerontology
Publisher
Springer Science and Business Media LLC
Published
2018-02-28
Volume
19
Issue
6
Pages
547-566
ISSN
  • 1389-5729
  • 1573-6768
DOI
10.1007/s10522-018-9750-z
PMC
PMC6223719
Cited by
181
References
43
Language
en
Licence
Funders
  • Wellcome Trust (110216)
  • Biotechnology and Biological Sciences Research Council ([BI Epigenetics ISP: BBS/E/B/000C0423])
  • National Institutes of Health (GM083048)

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